1FAQA

Raf-1 cysteine rich domain, nmr, 27 structures
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
52
structure length
52
Chain Sequence
LTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site.
pubmed doi rcsb
molecule tags Serine/threonine protein kinase
source organism Homo sapiens
molecule keywords RAF-1
total genus 4
structure length 52
sequence length 52
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 1996-09-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00130 C1_1 Phorbol esters/diacylglycerol binding domain (C1 domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.20 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1faqA00
1FARA 1TBOA 2QQEA 1W4RA 1R79A 3KY9A 2QQ0A 2WVJA 1FAQA 1KBFA 5FUVA 2J87A 3UEJA 3UGIA 2FNFX 2ELIA 4L9MA 4B6DA 1PTQA 1TBNA 1Y8FA 1RFHA 1XBTA 2DB6A 2GVIA 2VRWB 5FUXA 2B8TA 2JA1A 2YUUA 2ORWA 4FKDA 4UXIA 4UXJA 4UXHA 3UGLA 3UFFA 2QPOA 3UEYA 1XA6A 5FUWA 2ENNA 3E2IA 3BJIA 1XX6A 2E73A 2ORVA 1PTRA 5FUYA 2J9RA 1KBEA 2UZ3A 3UGDA 2ENZA 2ROWA 3CXLA
chains in the Genus database with same CATH superfamily
2SGEI 1YU6C 3SEKC 1KMAA 1N13A 2QQEA 2L7XA 2N71A 3FSYA 4E1RA 2CWHA 2M5XA 2ARPF 3VDUA 2J87A 1OMUA 2JYYA 1SGNI 5E3PA 4E1PA 1HPTA 1Y8FA 5HQ8A 1XBTA 1UVGA 1Z7KB 1WGTA 2XRCA 1MJBA 1SGEI 1UUCA 1W3SA 2YUUA 4UXIA 5E3QA 3OL0A 3UGLA 2B0UC 2X3TA 3RU0A 1BMOA 2OZUA 2K9HA 2ERWA 1P9ZA 2KCXA 1PJUA 3UEYA 3VDPA 1S20A 3TOBA 3TJQA 5FUWA 2JXDA 1M8CA 2ENNA 2NU1I 2V1CC 1WGCA 1CSOI 1OMTA 2UVOA 2V53A 3E2IA 2JW6A 3TO9A 3OXGA 1MJ9A 1TURA 2UZ3A 2ENZA 1HJAI 2V1CA 3R5CA 3CXLA 4L9MA 5J8CA 1FARA 1CE3A 1DS2I 1TBOA 2NU3I 1IY6A 1TUSA 1W4RA 1R0RI 1R79A 2QQ0A 2N17A 3R5AA 5FUVA 2CJSC 1FYBA 1ULKA 2FNFX 1CGII 4B6DA 1V1IA 2VRWB 1CT0I 5J8FA 1LR8A 1SGQI 1TBRR 2KMPA 3B4VC 3QAHA 5JHWC 2PQ8A 1LR7A 1MT1A 2B8TA 1K7VA 2DIPA 2E5RA 4UXJA 3R5DA 4SGBI 2RC4A 1LR9A 9WGAA 3D00A 3SGQI 1IY5A 1CT4I 1NUBA 5EX0A 1VDDA 3TO6A 2OU2A 3BJIA 3E59A 2GKVA 2A20A 2L8EA 3OVOA 1SGRI 3SGBI 4AMLA 3FC3A 1IW4A 1TOTA 3UOEA 2LEOA 3PDNA 2Y0MA 1YTPA 3VE5A 1OVOA 2KMOA 1PPFI 3MEKA 3OXFA 5E3RA 2JZMA 1DS3I 2RIJA 2KMQA 1SGYI 3UEJA 1FY7A 3OXLA 1CGJI 1TBNA 1RFHA 1SGDI 2DB6A 2QQDA 3R5BA 3GOXA 2ORWA 4GI3C 1SGPI 2OVOA 2WGCA 4JCVE 1U5KA 2ODDA 2SGDI 2QPOA 5DAEA 1NXUA 3UFFA 2N1AB 2N52A 7WGAA 1OYVI 2LUYA 2P6AC 2LB7A 1ULNA 1PCEA 1Y1CA 3TOAA 4DNCA 1H0ZA 1HDLA 2YQPA 3HH2C 2GKTI 1UVFA 1CT2I 1P9GA 2QQCA 1TBQR 2E73A 1WTJA 1PTRA 1HEVA 4WP4A 2CWFA 5EX3A 1Q9BA 1X4SA 2ROWA 4UXHA 1M8BA 1BUSA 3TO7A 1X74A 5CCMA 5CCLA 1MJAA 1TIHA 1ULMA 2OD1A 3KY9A 2WVJA 1K7UA 1FAQA 2NU2I 1KBFA 1UHAA 2GIVA 3UGIA 2BUSA 5HI7A 3FSXA 2ELIA 2X52A 1PTQA 5FUXA 1K7TA 2DKVA 2GVIA 2SGPI 1Z2IA 4HGUA 2JA1A 2SGFI 4FKDA 2KMRA 3QTLD 3QWPA 2SGQI 1TGSI 2GKRI 4OVOA 1AN1I 2F3CI 4MPIA 1XA6A 2NU0I 1CHOI 2WCYA 4A24A 1XX6A 1Y1BA 2ORVA 5FUYA 2J9RA 1WKXA 2CWGA 2NU4I 1KBEA 1V1HA 3UGDA 2W0TA
chains in the Genus database with same CATH topology
2SGEI 1YU6C 3SEKC 1KMAA 1N13A 2QQEA 2L7XA 2N71A 4E1RA 2M5XA 2ARPF 3VDUA 2J87A 1OMUA 2JYYA 1SGNI 4E1PA 1HPTA 1Y8FA 5HQ8A 1XBTA 1UVGA 1Z7KB 2XRCA 1SGEI 1UUCA 1W3SA 2YUUA 4UXIA 3OL0A 3UGLA 2B0UC 3RU0A 1BMOA 2K9HA 2ERWA 2KCXA 1PJUA 3UEYA 3VDPA 3TJQA 5FUWA 2JXDA 1M8CA 2ENNA 2NU1I 2V1CC 3E2IA 1CSOI 1OMTA 2V53A 2JW6A 3OXGA 1TURA 2UZ3A 2V1CA 2ENZA 1HJAI 4L9MA 3CXLA 1FARA 1CE3A 1DS2I 1TBOA 2NU3I 1IY6A 1TUSA 1W4RA 1R0RI 1R79A 2QQ0A 2N17A 5FUVA 2CJSC 1FYBA 2FNFX 1CGII 4B6DA 1V1IA 2VRWB 1CT0I 1LR8A 1SGQI 1TBRR 2KMPA 3B4VC 5JHWC 1LR7A 1MT1A 2B8TA 2DIPA 2E5RA 4UXJA 4SGBI 1LR9A 3D00A 3SGQI 1IY5A 1CT4I 1NUBA 5EX0A 1VDDA 3BJIA 3E59A 2GKVA 2A20A 2L8EA 3OVOA 1SGRI 3SGBI 3FC3A 1IW4A 1TOTA 2LEOA 3PDNA 1YTPA 3VE5A 1OVOA 2KMOA 1PPFI 3MEKA 3OXFA 2JZMA 1DS3I 2KMQA 1SGYI 3UEJA 3OXLA 1CGJI 1TBNA 1RFHA 1SGDI 2DB6A 2QQDA 3GOXA 2ORWA 4GI3C 1SGPI 2OVOA 4JCVE 1U5KA 2ODDA 2SGDI 2QPOA 5DAEA 3UFFA 2N1AB 2N52A 1OYVI 2LUYA 2P6AC 1PCEA 1Y1CA 1H0ZA 1HDLA 2YQPA 3HH2C 2GKTI 1UVFA 1CT2I 2QQCA 1TBQR 2E73A 1PTRA 5EX3A 1X4SA 4UXHA 2ROWA 1M8BA 1BUSA 1X74A 5CCMA 5CCLA 1TIHA 2OD1A 3KY9A 2WVJA 1FAQA 2NU2I 1KBFA 3UGIA 2BUSA 5HI7A 2ELIA 1PTQA 5FUXA 2GVIA 2SGPI 4HGUA 2JA1A 2SGFI 4FKDA 2KMRA 3QTLD 3QWPA 2SGQI 1TGSI 2GKRI 4OVOA 1AN1I 2F3CI 1XA6A 2NU0I 1CHOI 2WCYA 4A24A 1XX6A 1Y1BA 2ORVA 5FUYA 2J9RA 2NU4I 1KBEA 1V1HA 3UGDA 2W0TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FAR A;  1TBO A;  2QQE A;  1W4R A;  1R79 A;  3KY9 A;  2QQ0 A;  2WVJ A;  1FAQ A;  1KBF A;  5FUV A;  2J87 A;  3UEJ A;  3UGI A;  2FNF X;  2ELI A;  4L9M A;  4B6D A;  1PTQ A;  1TBN A;  1Y8F A;  1RFH A;  1XBT A;  2DB6 A;  2GVI A;  2VRW B;  5FUX A;  2B8T A;  2JA1 A;  2YUU A;  2ORW A;  4FKD A;  4UXI A;  4UXJ A;  4UXH A;  3UGL A;  3UFF A;  2QPO A;  3UEY A;  1XA6 A;  5FUW A;  2ENN A;  3E2I A;  3BJI A;  1XX6 A;  2E73 A;  2ORV A;  1PTR A;  5FUY A;  2J9R A;  1KBE A;  2UZ3 A;  3UGD A;  2ENZ A;  2ROW A;  3CXL A; 
#chains in the Genus database with same CATH topology
 2SGE I;  1YU6 C;  3SEK C;  1KMA A;  1N13 A;  2QQE A;  2L7X A;  2N71 A;  3FSY A;  4E1R A;  2CWH A;  2M5X A;  2ARP F;  3VDU A;  2J87 A;  1OMU A;  2JYY A;  1SGN I;  5E3P A;  4E1P A;  1HPT A;  1Y8F A;  5HQ8 A;  1XBT A;  1UVG A;  1Z7K B;  1WGT A;  2XRC A;  1MJB A;  1SGE I;  1UUC A;  1W3S A;  2YUU A;  4UXI A;  5E3Q A;  3OL0 A;  3UGL A;  2B0U C;  2X3T A;  3RU0 A;  1BMO A;  2OZU A;  2K9H A;  2ERW A;  1P9Z A;  2KCX A;  1PJU A;  3UEY A;  3VDP A;  1S20 A;  3TOB A;  3TJQ A;  5FUW A;  2JXD A;  1M8C A;  2ENN A;  2NU1 I;  2V1C C;  1WGC A;  1CSO I;  1OMT A;  2UVO A;  2V53 A;  3E2I A;  2JW6 A;  3TO9 A;  3OXG A;  1MJ9 A;  1TUR A;  2UZ3 A;  2ENZ A;  1HJA I;  2V1C A;  3R5C A;  3CXL A;  4L9M A;  5J8C A;  1FAR A;  1CE3 A;  1DS2 I;  1TBO A;  2NU3 I;  1IY6 A;  1TUS A;  1W4R A;  1R0R I;  1R79 A;  2QQ0 A;  2N17 A;  3R5A A;  5FUV A;  2CJS C;  1FYB A;  1ULK A;  2FNF X;  1CGI I;  4B6D A;  1V1I A;  2VRW B;  1CT0 I;  5J8F A;  1LR8 A;  1SGQ I;  1TBR R;  2KMP A;  3B4V C;  3QAH A;  5JHW C;  2PQ8 A;  1LR7 A;  1MT1 A;  2B8T A;  1K7V A;  2DIP A;  2E5R A;  4UXJ A;  3R5D A;  4SGB I;  2RC4 A;  1LR9 A;  9WGA A;  3D00 A;  3SGQ I;  1IY5 A;  1CT4 I;  1NUB A;  5EX0 A;  1VDD A;  3TO6 A;  2OU2 A;  3BJI A;  3E59 A;  2GKV A;  2A20 A;  2L8E A;  3OVO A;  1SGR I;  3SGB I;  4AML A;  3FC3 A;  1IW4 A;  1TOT A;  3UOE A;  2LEO A;  3PDN A;  2Y0M A;  1YTP A;  3VE5 A;  1OVO A;  2KMO A;  1PPF I;  3MEK A;  3OXF A;  5E3R A;  2JZM A;  1DS3 I;  2RIJ A;  2KMQ A;  1SGY I;  3UEJ A;  1FY7 A;  3OXL A;  1CGJ I;  1TBN A;  1RFH A;  1SGD I;  2DB6 A;  2QQD A;  3R5B A;  3GOX A;  2ORW A;  4GI3 C;  1SGP I;  2OVO A;  2WGC A;  4JCV E;  1U5K A;  2ODD A;  2SGD I;  2QPO A;  5DAE A;  1NXU A;  3UFF A;  2N1A B;  2N52 A;  7WGA A;  1OYV I;  2LUY A;  2P6A C;  2LB7 A;  1ULN A;  1PCE A;  1Y1C A;  3TOA A;  4DNC A;  1H0Z A;  1HDL A;  2YQP A;  3HH2 C;  2GKT I;  1UVF A;  1CT2 I;  1P9G A;  2QQC A;  1TBQ R;  2E73 A;  1WTJ A;  1PTR A;  1HEV A;  4WP4 A;  2CWF A;  5EX3 A;  1Q9B A;  1X4S A;  2ROW A;  4UXH A;  1M8B A;  1BUS A;  3TO7 A;  1X74 A;  5CCM A;  5CCL A;  1MJA A;  1TIH A;  1ULM A;  2OD1 A;  3KY9 A;  2WVJ A;  1K7U A;  1FAQ A;  2NU2 I;  1KBF A;  1UHA A;  2GIV A;  3UGI A;  2BUS A;  5HI7 A;  3FSX A;  2ELI A;  2X52 A;  1PTQ A;  5FUX A;  1K7T A;  2DKV A;  2GVI A;  2SGP I;  1Z2I A;  4HGU A;  2JA1 A;  2SGF I;  4FKD A;  2KMR A;  3QTL D;  3QWP A;  2SGQ I;  1TGS I;  2GKR I;  4OVO A;  1AN1 I;  2F3C I;  4MPI A;  1XA6 A;  2NU0 I;  1CHO I;  2WCY A;  4A24 A;  1XX6 A;  1Y1B A;  2ORV A;  5FUY A;  2J9R A;  1WKX A;  2CWG A;  2NU4 I;  1KBE A;  1V1H A;  3UGD A;  2W0T A; 
#chains in the Genus database with same CATH homology
 2SGE I;  1YU6 C;  3SEK C;  1KMA A;  1N13 A;  2QQE A;  2L7X A;  2N71 A;  4E1R A;  2M5X A;  2ARP F;  3VDU A;  2J87 A;  1OMU A;  2JYY A;  1SGN I;  4E1P A;  1HPT A;  1Y8F A;  5HQ8 A;  1XBT A;  1UVG A;  1Z7K B;  2XRC A;  1SGE I;  1UUC A;  1W3S A;  2YUU A;  4UXI A;  3OL0 A;  3UGL A;  2B0U C;  3RU0 A;  1BMO A;  2K9H A;  2ERW A;  2KCX A;  1PJU A;  3UEY A;  3VDP A;  3TJQ A;  5FUW A;  2JXD A;  1M8C A;  2ENN A;  2NU1 I;  2V1C C;  3E2I A;  1CSO I;  1OMT A;  2V53 A;  2JW6 A;  3OXG A;  1TUR A;  2UZ3 A;  2V1C A;  2ENZ A;  1HJA I;  4L9M A;  3CXL A;  1FAR A;  1CE3 A;  1DS2 I;  1TBO A;  2NU3 I;  1IY6 A;  1TUS A;  1W4R A;  1R0R I;  1R79 A;  2QQ0 A;  2N17 A;  5FUV A;  2CJS C;  1FYB A;  2FNF X;  1CGI I;  4B6D A;  1V1I A;  2VRW B;  1CT0 I;  1LR8 A;  1SGQ I;  1TBR R;  2KMP A;  3B4V C;  5JHW C;  1LR7 A;  1MT1 A;  2B8T A;  2DIP A;  2E5R A;  4UXJ A;  4SGB I;  1LR9 A;  3D00 A;  3SGQ I;  1IY5 A;  1CT4 I;  1NUB A;  5EX0 A;  1VDD A;  3BJI A;  3E59 A;  2GKV A;  2A20 A;  2L8E A;  3OVO A;  1SGR I;  3SGB I;  3FC3 A;  1IW4 A;  1TOT A;  2LEO A;  3PDN A;  1YTP A;  3VE5 A;  1OVO A;  2KMO A;  1PPF I;  3MEK A;  3OXF A;  2JZM A;  1DS3 I;  2KMQ A;  1SGY I;  3UEJ A;  3OXL A;  1CGJ I;  1TBN A;  1RFH A;  1SGD I;  2DB6 A;  2QQD A;  3GOX A;  2ORW A;  4GI3 C;  1SGP I;  2OVO A;  4JCV E;  1U5K A;  2ODD A;  2SGD I;  2QPO A;  5DAE A;  3UFF A;  2N1A B;  2N52 A;  1OYV I;  2LUY A;  2P6A C;  1PCE A;  1Y1C A;  1H0Z A;  1HDL A;  2YQP A;  3HH2 C;  2GKT I;  1UVF A;  1CT2 I;  2QQC A;  1TBQ R;  2E73 A;  1PTR A;  5EX3 A;  1X4S A;  4UXH A;  2ROW A;  1M8B A;  1BUS A;  1X74 A;  5CCM A;  5CCL A;  1TIH A;  2OD1 A;  3KY9 A;  2WVJ A;  1FAQ A;  2NU2 I;  1KBF A;  3UGI A;  2BUS A;  5HI7 A;  2ELI A;  1PTQ A;  5FUX A;  2GVI A;  2SGP I;  4HGU A;  2JA1 A;  2SGF I;  4FKD A;  2KMR A;  3QTL D;  3QWP A;  2SGQ I;  1TGS I;  2GKR I;  4OVO A;  1AN1 I;  2F3C I;  1XA6 A;  2NU0 I;  1CHO I;  2WCY A;  4A24 A;  1XX6 A;  1Y1B A;  2ORV A;  5FUY A;  2J9R A;  2NU4 I;  1KBE A;  1V1H A;  3UGD A;  2W0T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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