1IW4A

Solution structure of ascidian trypsin inhibitor
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
55
structure length
55
Chain Sequence
AHMDCTEFNPLCRCNKMLGDLICAVIGDAKEEHRNMCALCCEHPGGFEYSNGPCE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of ascidian trypsin inhibitor determined by nuclear magnetic resonance spectroscopy.
pubmed doi rcsb
molecule tags Protein binding
molecule keywords trypsin inhibitor
total genus 8
structure length 55
sequence length 55
ec nomenclature
pdb deposition date 2002-04-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1iw4A00
1CGII 2OVOA 2BUSA 1SGNI 3HH2C 1SGRI 3SEKC 1TUSA 2GKRI 2SGFI 1CT0I 2QQDA 4HGUA 1FYBA 1OYVI 2N71A 1CT4I 1CGJI 1CT2I 1TGSI 2N17A 1KMAA 1NUBA 1DS2I 1H0ZA 1OMTA 3SGQI 2SGPI 1SGPI 2KMQA 1BMOA 2ERWA 1PJUA 2SGQI 2B0UC 1SGQI 1LR7A 1PCEA 2WCYA 2NU0I 5DAEA 1AN1I 1HDLA 2JXDA 2V53A 3TJQA 1OMUA 2KCXA 2F3CI 2P6AC 2M5XA 1LR9A 1BUSA 1TIHA 2GKTI 1Z7KB 4GI3C 1TURA 1TBQR 1PPFI 1MT1A 1M8CA 2KMRA 2N52A 1SGYI 2NU3I 1UVGA 1N13A 4SGBI 1IW4A 1Y1BA 2LEOA 3OVOA 1OVOA 1Y1CA 1HJAI 1SGEI 1HPTA 1UUCA 2KMPA 1LR8A 4OVOA 2SGEI 2NU1I 1R0RI 1CSOI 2NU4I 2NU2I 1TBRR 1YU6C 2SGDI 1YTPA 1IY5A 1CHOI 5JHWC 1UVFA 3SGBI 2JYYA 3QTLD 2JZMA 1IY6A 2XRCA 2KMOA 1M8BA 1CE3A 1SGDI 2QQCA 1DS3I 3B4VC 2GKVA 2ARPF
chains in the Genus database with same CATH superfamily
1VDDA 1CGII 1W4RA 3R5BA 5CCMA 2OVOA 2BUSA 1SGNI 3HH2C 1KBFA 1SGRI 2FNFX 3UEJA 2WVJA 3D00A 1W3SA 3GOXA 3SEKC 1WGTA 1XX6A 2J87A 2K9HA 1TUSA 2YQPA 2GKRI 2SGFI 7WGAA 1CT0I 3E59A 1FARA 2QQDA 3OL0A 2ELIA 4WP4A 2B8TA 4L9MA 1WKXA 4HGUA 4UXIA 1FYBA 5E3PA 1HEVA 1OYVI 1P9GA 2Y0MA 1FAQA 3UGDA 2N71A 1CT4I 4B6DA 1CGJI 1XBTA 2UZ3A 5HQ8A 1CT2I 1TGSI 2N17A 3VE5A 1RFHA 1NUBA 1Q9BA 1DS2I 2ROWA 2WGCA 3FSXA 3QAHA 3R5DA 5E3QA 1H0ZA 1OMTA 3TO6A 3SGQI 3QWPA 2SGPI 1SGPI 2KMQA 1BMOA 1TOTA 2L7XA 2ERWA 1PJUA 2SGQI 1P9ZA 2B0UC 1SGQI 2ORVA 1LR7A 1NXUA 1PCEA 2ORWA 2NU0I 2WCYA 3R5AA 5DAEA 2JA1A 3UEYA 4E1PA 1AN1I 2UVOA 3RU0A 1HDLA 2JXDA 1K7VA 1Y8FA 2QQEA 2X52A 2ENNA 2V53A 3TOAA 2V1CA 5EX0A 3TJQA 1R79A 3UOEA 1OMUA 2KCXA 1MJBA 2F3CI 2P6AC 2W0TA 3VDPA 2M5XA 1LR9A 1BUSA 1TIHA 1X74A 2GKTI 1Z7KB 2E73A 4GI3C 1TURA 1TBQR 3FSYA 2J9RA 3OVOA 1PPFI 1V1HA 2LUYA 4E1RA 1MT1A 1U5KA 2N1AB 1M8CA 2KMRA 2N52A 2QPOA 1SGYI 2NU3I 2JW6A 3UFFA 1TBOA 5FUWA 2E5RA 3TO7A 1UVGA 1N13A 1V1IA 2A20A 1Y1BA 2GVIA 2LB7A 1OVOA 2LEOA 2QQ0A 3CXLA 1Y1CA 2ENZA 2OU2A 2OD1A 1HJAI 1SGEI 3BJIA 3R5CA 1HPTA 1S20A 5FUYA 1UUCA 2KMPA 4DNCA 1FY7A 1LR8A 4OVOA 1K7UA 2SGEI 2NU1I 1R0RI 2PQ8A 1CSOI 2NU4I 2CWFA 5HI7A 2RC4A 2CWHA 2NU2I 1ULMA 4MPIA 1TBRR 1TBNA 1YU6C 3MEKA 2SGDI 2CJSC 5FUVA 1YTPA 3TO9A 9WGAA 1IY5A 5FUXA 1ULNA 5J8CA 3UGIA 1CHOI 2CWGA 3UGLA 2OZUA 5JHWC 1UVFA 1WTJA 2VRWB 1WGCA 4JCVE 3SGBI 4AMLA 4UXHA 2JYYA 2X3TA 1Z2IA 3QTLD 4UXJA 5E3RA 3FC3A 3OXLA 1KMAA 3E2IA 2JZMA 3KY9A 2GIVA 2XRCA 1IY6A 2DKVA 1KBEA 1M8BA 2KMOA 2V1CC 3VDUA 1PTQA 2RIJA 3OXFA 1CE3A 5EX3A 1SGDI 5CCLA 1PTRA 2QQCA 5J8FA 1MJ9A 2ODDA 1DS3I 1X4SA 4SGBI 4A24A 1ULKA 4FKDA 1MJAA 2L8EA 3TOBA 1K7TA 3PDNA 1UHAA 1XA6A 2DIPA 3B4VC 2DB6A 2GKVA 3OXGA 2YUUA 2ARPF 1IW4A
chains in the Genus database with same CATH topology
1VDDA 1CGII 1W4RA 5CCMA 2OVOA 2BUSA 1SGNI 3HH2C 1KBFA 1SGRI 2FNFX 3UEJA 2WVJA 3D00A 1W3SA 3GOXA 3SEKC 1XX6A 2J87A 2K9HA 1TUSA 2YQPA 2GKRI 2SGFI 1CT0I 3E59A 1FARA 2QQDA 3OL0A 2ELIA 2B8TA 4L9MA 4HGUA 4UXIA 1FYBA 1OYVI 1FAQA 3UGDA 2N71A 1CT4I 4B6DA 1CGJI 1XBTA 2UZ3A 5HQ8A 1CT2I 1TGSI 2N17A 3VE5A 1RFHA 1NUBA 1DS2I 2ROWA 1KMAA 1H0ZA 1OMTA 3SGQI 3QWPA 2SGPI 1SGPI 2KMQA 1BMOA 1TOTA 2L7XA 2ERWA 1PJUA 2SGQI 2B0UC 1SGQI 2ORVA 1LR7A 1PCEA 2ORWA 2WCYA 2NU0I 5DAEA 2JA1A 3UEYA 4E1PA 1AN1I 1HDLA 3RU0A 2JXDA 1Y8FA 2QQEA 2ENNA 2V53A 2V1CA 5EX0A 3TJQA 1R79A 1OMUA 2KCXA 2F3CI 2P6AC 2W0TA 3VDPA 2M5XA 1LR9A 1BUSA 1TIHA 1X74A 2GKTI 1Z7KB 2E73A 4GI3C 1TURA 1TBQR 2J9RA 1PPFI 1V1HA 2LUYA 4E1RA 1MT1A 1U5KA 2N1AB 1M8CA 2KMRA 2N52A 2QPOA 1SGYI 2NU3I 2JW6A 3UFFA 1TBOA 5FUWA 2E5RA 1UVGA 1N13A 1V1IA 2A20A 1Y1BA 2GVIA 2LEOA 1OVOA 2QQ0A 3CXLA 3OVOA 1Y1CA 2ENZA 3VDUA 2OD1A 1HJAI 1SGEI 3BJIA 1HPTA 5FUYA 1UUCA 2KMPA 1LR8A 4OVOA 2SGEI 2NU1I 1R0RI 1CSOI 2NU4I 5HI7A 2NU2I 1TBRR 1TBNA 1YU6C 3MEKA 2SGDI 2CJSC 5FUVA 1YTPA 1IY5A 5FUXA 3UGIA 1CHOI 3UGLA 5JHWC 1UVFA 2VRWB 3SGBI 4JCVE 4UXHA 2JYYA 3QTLD 4UXJA 3FC3A 3OXLA 3E2IA 2JZMA 3KY9A 1IY6A 2XRCA 2KMOA 1KBEA 1M8BA 2V1CC 1PTQA 3OXFA 1CE3A 5EX3A 1SGDI 5CCLA 1PTRA 2QQCA 2ODDA 1DS3I 1X4SA 4SGBI 4A24A 4FKDA 2L8EA 3PDNA 1XA6A 2DIPA 3B4VC 2DB6A 2GKVA 3OXGA 2YUUA 2ARPF 1IW4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CGI I;  2OVO A;  2BUS A;  1SGN I;  3HH2 C;  1SGR I;  3SEK C;  1TUS A;  2GKR I;  2SGF I;  1CT0 I;  2QQD A;  4HGU A;  1FYB A;  1OYV I;  2N71 A;  1CT4 I;  1CGJ I;  1CT2 I;  1TGS I;  2N17 A;  1KMA A;  1NUB A;  1DS2 I;  1H0Z A;  1OMT A;  3SGQ I;  2SGP I;  1SGP I;  2KMQ A;  1BMO A;  2ERW A;  1PJU A;  2SGQ I;  2B0U C;  1SGQ I;  1LR7 A;  1PCE A;  2WCY A;  2NU0 I;  5DAE A;  1AN1 I;  1HDL A;  2JXD A;  2V53 A;  3TJQ A;  1OMU A;  2KCX A;  2F3C I;  2P6A C;  2M5X A;  1LR9 A;  1BUS A;  1TIH A;  2GKT I;  1Z7K B;  4GI3 C;  1TUR A;  1TBQ R;  1PPF I;  1MT1 A;  1M8C A;  2KMR A;  2N52 A;  1SGY I;  2NU3 I;  1UVG A;  1N13 A;  4SGB I;  1IW4 A;  1Y1B A;  2LEO A;  3OVO A;  1OVO A;  1Y1C A;  1HJA I;  1SGE I;  1HPT A;  1UUC A;  2KMP A;  1LR8 A;  4OVO A;  2SGE I;  2NU1 I;  1R0R I;  1CSO I;  2NU4 I;  2NU2 I;  1TBR R;  1YU6 C;  2SGD I;  1YTP A;  1IY5 A;  1CHO I;  5JHW C;  1UVF A;  3SGB I;  2JYY A;  3QTL D;  2JZM A;  1IY6 A;  2XRC A;  2KMO A;  1M8B A;  1CE3 A;  1SGD I;  2QQC A;  1DS3 I;  3B4V C;  2GKV A;  2ARP F; 
#chains in the Genus database with same CATH topology
 1VDD A;  1CGI I;  1W4R A;  3R5B A;  5CCM A;  2OVO A;  2BUS A;  1SGN I;  3HH2 C;  1KBF A;  1SGR I;  2FNF X;  3UEJ A;  2WVJ A;  3D00 A;  1W3S A;  3GOX A;  3SEK C;  1WGT A;  1XX6 A;  2J87 A;  2K9H A;  1TUS A;  2YQP A;  2GKR I;  2SGF I;  7WGA A;  1CT0 I;  3E59 A;  1FAR A;  2QQD A;  3OL0 A;  2ELI A;  4WP4 A;  2B8T A;  4L9M A;  1WKX A;  4HGU A;  4UXI A;  1FYB A;  5E3P A;  1HEV A;  1OYV I;  1P9G A;  2Y0M A;  1FAQ A;  3UGD A;  2N71 A;  1CT4 I;  4B6D A;  1CGJ I;  1XBT A;  2UZ3 A;  5HQ8 A;  1CT2 I;  1TGS I;  2N17 A;  3VE5 A;  1RFH A;  1NUB A;  1Q9B A;  1DS2 I;  2ROW A;  2WGC A;  3FSX A;  3QAH A;  3R5D A;  5E3Q A;  1H0Z A;  1OMT A;  3TO6 A;  3SGQ I;  3QWP A;  2SGP I;  1SGP I;  2KMQ A;  1BMO A;  1TOT A;  2L7X A;  2ERW A;  1PJU A;  2SGQ I;  1P9Z A;  2B0U C;  1SGQ I;  2ORV A;  1LR7 A;  1NXU A;  1PCE A;  2ORW A;  2NU0 I;  2WCY A;  3R5A A;  5DAE A;  2JA1 A;  3UEY A;  4E1P A;  1AN1 I;  2UVO A;  3RU0 A;  1HDL A;  2JXD A;  1K7V A;  1Y8F A;  2QQE A;  2X52 A;  2ENN A;  2V53 A;  3TOA A;  2V1C A;  5EX0 A;  3TJQ A;  1R79 A;  3UOE A;  1OMU A;  2KCX A;  1MJB A;  2F3C I;  2P6A C;  2W0T A;  3VDP A;  2M5X A;  1LR9 A;  1BUS A;  1TIH A;  1X74 A;  2GKT I;  1Z7K B;  2E73 A;  4GI3 C;  1TUR A;  1TBQ R;  3FSY A;  2J9R A;  3OVO A;  1PPF I;  1V1H A;  2LUY A;  4E1R A;  1MT1 A;  1U5K A;  2N1A B;  1M8C A;  2KMR A;  2N52 A;  2QPO A;  1SGY I;  2NU3 I;  2JW6 A;  3UFF A;  1TBO A;  5FUW A;  2E5R A;  3TO7 A;  1UVG A;  1N13 A;  1V1I A;  2A20 A;  1Y1B A;  2GVI A;  2LB7 A;  1OVO A;  2LEO A;  2QQ0 A;  3CXL A;  1Y1C A;  2ENZ A;  2OU2 A;  2OD1 A;  1HJA I;  1SGE I;  3BJI A;  3R5C A;  1HPT A;  1S20 A;  5FUY A;  1UUC A;  2KMP A;  4DNC A;  1FY7 A;  1LR8 A;  4OVO A;  1K7U A;  2SGE I;  2NU1 I;  1R0R I;  2PQ8 A;  1CSO I;  2NU4 I;  2CWF A;  5HI7 A;  2RC4 A;  2CWH A;  2NU2 I;  1ULM A;  4MPI A;  1TBR R;  1TBN A;  1YU6 C;  3MEK A;  2SGD I;  2CJS C;  5FUV A;  1YTP A;  3TO9 A;  9WGA A;  1IY5 A;  5FUX A;  1ULN A;  5J8C A;  3UGI A;  1CHO I;  2CWG A;  3UGL A;  2OZU A;  5JHW C;  1UVF A;  1WTJ A;  2VRW B;  1WGC A;  4JCV E;  3SGB I;  4AML A;  4UXH A;  2JYY A;  2X3T A;  1Z2I A;  3QTL D;  4UXJ A;  5E3R A;  3FC3 A;  3OXL A;  1KMA A;  3E2I A;  2JZM A;  3KY9 A;  2GIV A;  2XRC A;  1IY6 A;  2DKV A;  1KBE A;  1M8B A;  2KMO A;  2V1C C;  3VDU A;  1PTQ A;  2RIJ A;  3OXF A;  1CE3 A;  5EX3 A;  1SGD I;  5CCL A;  1PTR A;  2QQC A;  5J8F A;  1MJ9 A;  2ODD A;  1DS3 I;  1X4S A;  4SGB I;  4A24 A;  1ULK A;  4FKD A;  1MJA A;  2L8E A;  3TOB A;  1K7T A;  3PDN A;  1UHA A;  1XA6 A;  2DIP A;  3B4V C;  2DB6 A;  2GKV A;  3OXG A;  2YUU A;  2ARP F;  1IW4 A; 
#chains in the Genus database with same CATH homology
 1VDD A;  1CGI I;  1W4R A;  5CCM A;  2OVO A;  2BUS A;  1SGN I;  3HH2 C;  1KBF A;  1SGR I;  2FNF X;  3UEJ A;  2WVJ A;  3D00 A;  1W3S A;  3GOX A;  3SEK C;  1XX6 A;  2J87 A;  2K9H A;  1TUS A;  2YQP A;  2GKR I;  2SGF I;  1CT0 I;  3E59 A;  1FAR A;  2QQD A;  3OL0 A;  2ELI A;  2B8T A;  4L9M A;  4HGU A;  4UXI A;  1FYB A;  1OYV I;  1FAQ A;  3UGD A;  2N71 A;  1CT4 I;  4B6D A;  1CGJ I;  1XBT A;  2UZ3 A;  5HQ8 A;  1CT2 I;  1TGS I;  2N17 A;  3VE5 A;  1RFH A;  1NUB A;  1DS2 I;  2ROW A;  1KMA A;  1H0Z A;  1OMT A;  3SGQ I;  3QWP A;  2SGP I;  1SGP I;  2KMQ A;  1BMO A;  1TOT A;  2L7X A;  2ERW A;  1PJU A;  2SGQ I;  2B0U C;  1SGQ I;  2ORV A;  1LR7 A;  1PCE A;  2ORW A;  2WCY A;  2NU0 I;  5DAE A;  2JA1 A;  3UEY A;  4E1P A;  1AN1 I;  1HDL A;  3RU0 A;  2JXD A;  1Y8F A;  2QQE A;  2ENN A;  2V53 A;  2V1C A;  5EX0 A;  3TJQ A;  1R79 A;  1OMU A;  2KCX A;  2F3C I;  2P6A C;  2W0T A;  3VDP A;  2M5X A;  1LR9 A;  1BUS A;  1TIH A;  1X74 A;  2GKT I;  1Z7K B;  2E73 A;  4GI3 C;  1TUR A;  1TBQ R;  2J9R A;  1PPF I;  1V1H A;  2LUY A;  4E1R A;  1MT1 A;  1U5K A;  2N1A B;  1M8C A;  2KMR A;  2N52 A;  2QPO A;  1SGY I;  2NU3 I;  2JW6 A;  3UFF A;  1TBO A;  5FUW A;  2E5R A;  1UVG A;  1N13 A;  1V1I A;  2A20 A;  1Y1B A;  2GVI A;  2LEO A;  1OVO A;  2QQ0 A;  3CXL A;  3OVO A;  1Y1C A;  2ENZ A;  3VDU A;  2OD1 A;  1HJA I;  1SGE I;  3BJI A;  1HPT A;  5FUY A;  1UUC A;  2KMP A;  1LR8 A;  4OVO A;  2SGE I;  2NU1 I;  1R0R I;  1CSO I;  2NU4 I;  5HI7 A;  2NU2 I;  1TBR R;  1TBN A;  1YU6 C;  3MEK A;  2SGD I;  2CJS C;  5FUV A;  1YTP A;  1IY5 A;  5FUX A;  3UGI A;  1CHO I;  3UGL A;  5JHW C;  1UVF A;  2VRW B;  3SGB I;  4JCV E;  4UXH A;  2JYY A;  3QTL D;  4UXJ A;  3FC3 A;  3OXL A;  3E2I A;  2JZM A;  3KY9 A;  1IY6 A;  2XRC A;  2KMO A;  1KBE A;  1M8B A;  2V1C C;  1PTQ A;  3OXF A;  1CE3 A;  5EX3 A;  1SGD I;  5CCL A;  1PTR A;  2QQC A;  2ODD A;  1DS3 I;  1X4S A;  4SGB I;  4A24 A;  4FKD A;  2L8E A;  3PDN A;  1XA6 A;  2DIP A;  3B4V C;  2DB6 A;  2GKV A;  3OXG A;  2YUU A;  2ARP F;  1IW4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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