1R0RI

1.1 angstrom resolution structure of the complex between the protein inhibitor, omtky3, and the serine protease, subtilisin carlsberg
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
51
structure length
51
Chain Sequence
VDCSEYPKPACTLEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and energetics of protein-protein interactions: the role of conformational heterogeneity in OMTKY3 binding to serine proteases
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords subtilisin carlsberg
total genus 14
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 2003-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1r0rI00
4SGBI 1LR8A 2NU2I 2P6AC 1TBQR 2QQDA 2JYYA 1OYVI 2F3CI 1CGII 3QTLD 1NUBA 1HDLA 1MT1A 2N17A 2SGFI 2KMPA 1TIHA 1DS2I 1SGRI 1Y1CA 1IY5A 1PCEA 2JZMA 2SGQI 2OVOA 1M8CA 1R0RI 2M5XA 2SGEI 1KMAA 1H0ZA 2KMRA 1SGPI 2GKRI 1CT4I 1SGNI 2QQCA 3SGBI 2WCYA 1HJAI 1SGYI 1TUSA 2KCXA 3B4VC 3SGQI 1IY6A 1TBRR 1CGJI 1LR9A 2ERWA 2SGPI 2B0UC 1BUSA 1DS3I 1BMOA 5JHWC 1UVFA 1OMUA 1AN1I 2KMOA 4OVOA 1OVOA 2V53A 4HGUA 1SGDI 1CT2I 2ARPF 1YTPA 3OVOA 1M8BA 1TGSI 2NU4I 2NU0I 1CHOI 1FYBA 1TURA 1CSOI 2N71A 1Z7KB 2NU1I 1CE3A 1N13A 2XRCA 1Y1BA 2SGDI 2GKTI 1CT0I 3TJQA 4GI3C 1LR7A 1UUCA 2JXDA 2N52A 2BUSA 1SGQI 1IW4A 3HH2C 1YU6C 2LEOA 5DAEA 3SEKC 2GKVA 1OMTA 2KMQA 1HPTA 2NU3I 1UVGA 1SGEI 1PJUA 1PPFI
chains in the Genus database with same CATH superfamily
4SGBI 1PTQA 1NXUA 1R79A 2GIVA 2N1AB 2ODDA 5EX0A 3OXLA 2LB7A 2JA1A 2OD1A 1FAQA 1TBNA 4L9MA 2E5RA 5CCLA 2Y0MA 1LR8A 2NU2I 2P6AC 1TBQR 2RC4A 2DB6A 2QQDA 1ULMA 1OYVI 2JYYA 2A20A 2F3CI 1CGII 3QTLD 1NUBA 1HDLA 1MT1A 2B8TA 3UEJA 2N17A 1ULKA 2KMPA 2SGFI 3VE5A 1TIHA 1DS2I 1PTRA 2FNFX 1SGRI 4FKDA 1WKXA 1Y1CA 3TO9A 1HEVA 2DIPA 1IY5A 1PCEA 2JZMA 2SGQI 2YUUA 2WGCA 2OVOA 1M8CA 1R0RI 2WVJA 3FSXA 1XX6A 2M5XA 1K7VA 2SGEI 2UZ3A 2LUYA 1KMAA 1P9ZA 1X74A 1H0ZA 1V1HA 4B6DA 2KMRA 2QPOA 1SGPI 2CWGA 3D00A 2GKRI 1CT4I 1SGNI 2QQCA 2X52A 3SGBI 3R5AA 1Z2IA 1HJAI 2WCYA 5HI7A 1SGYI 4E1PA 1TUSA 2L7XA 5E3PA 2GVIA 2KCXA 3TOBA 3UGDA 2OU2A 2CJSC 3B4VC 3SGQI 1K7UA 1IY6A 1XA6A 1TBRR 1CGJI 2DKVA 2ELIA 1LR9A 2ERWA 2SGPI 2YQPA 2QQEA 5HQ8A 2ORWA 2B0UC 2ROWA 5J8CA 1K7TA 2VRWB 5CCMA 1BUSA 2W0TA 1DS3I 1BMOA 1TBOA 3UFFA 1UVFA 5JHWC 1OMUA 1RFHA 4DNCA 1FY7A 2CWFA 1VDDA 3UOEA 4AMLA 1AN1I 2PQ8A 2E73A 2KMOA 2QQ0A 3QWPA 4OVOA 1P9GA 2ORVA 1FARA 1OVOA 2V53A 2K9HA 4HGUA 4UXHA 9WGAA 2CWHA 3R5BA 1SGDI 2J9RA 1WGTA 2V1CC 1CT2I 1W4RA 3R5DA 4UXIA 2X3TA 2ARPF 1YTPA 3OVOA 4WP4A 5FUWA 3OXFA 1M8BA 3FSYA 2JW6A 3UGIA 1TGSI 1TOTA 2NU4I 2UVOA 5FUXA 1MJAA 2NU0I 1CHOI 2RIJA 1FYBA 1Q9BA 1TURA 1CSOI 2N71A 1UHAA 1Z7KB 2NU1I 3OXGA 3TO6A 1CE3A 1MJ9A 5EX3A 5FUVA 1N13A 2OZUA 4MPIA 2XRCA 3MEKA 3CXLA 1MJBA 1Y1BA 2ENNA 2SGDI 3BJIA 1CT0I 2GKTI 3TJQA 5FUYA 1U5KA 1KBEA 2J87A 3UEYA 4GI3C 5J8FA 3PDNA 1LR7A 3VDUA 4E1RA 1UUCA 2JXDA 2N52A 1Y8FA 2BUSA 2ENZA 3E59A 1X4SA 1SGQI 4JCVE 1IW4A 3RU0A 3HH2C 4UXJA 5E3QA 2L8EA 3KY9A 1YU6C 5E3RA 1W3SA 2LEOA 5DAEA 1WGCA 3FC3A 3SEKC 2V1CA 1ULNA 1XBTA 3GOXA 3TO7A 1V1IA 3R5CA 2GKVA 1OMTA 2KMQA 3TOAA 1HPTA 2NU3I 7WGAA 3OL0A 1KBFA 1UVGA 1SGEI 3UGLA 1PJUA 3QAHA 1S20A 4A24A 1PPFI 3E2IA 1WTJA 3VDPA
chains in the Genus database with same CATH topology
4SGBI 1PTQA 1R79A 2N1AB 2ODDA 5EX0A 3OXLA 2JA1A 2OD1A 1FAQA 1TBNA 4L9MA 2E5RA 5CCLA 1LR8A 2NU2I 2P6AC 1TBQR 2DB6A 2QQDA 2JYYA 1OYVI 2A20A 2F3CI 1CGII 3QTLD 1NUBA 1HDLA 1MT1A 2B8TA 3UEJA 2N17A 2SGFI 2KMPA 3VE5A 1TIHA 1DS2I 1PTRA 2FNFX 1SGRI 4FKDA 1Y1CA 2DIPA 1IY5A 1PCEA 2JZMA 2SGQI 2YUUA 2OVOA 1M8CA 1R0RI 2WVJA 1XX6A 2M5XA 2SGEI 2UZ3A 2LUYA 1KMAA 1X74A 1H0ZA 1V1HA 4B6DA 2KMRA 2QPOA 1SGPI 3D00A 2GKRI 1CT4I 1SGNI 2QQCA 3SGBI 2WCYA 1HJAI 5HI7A 1SGYI 4E1PA 1TUSA 2L7XA 2GVIA 2KCXA 3UGDA 2CJSC 3B4VC 3SGQI 1IY6A 1XA6A 1TBRR 1CGJI 2ELIA 1LR9A 2ERWA 2SGPI 2YQPA 2QQEA 5HQ8A 2ORWA 2B0UC 2ROWA 3GOXA 2VRWB 5CCMA 1BUSA 2W0TA 1DS3I 1BMOA 1TBOA 3UFFA 1UVFA 5JHWC 1OMUA 1RFHA 1VDDA 1AN1I 2E73A 2KMOA 2QQ0A 3QWPA 4OVOA 2ORVA 1FARA 1OVOA 2V53A 2K9HA 4HGUA 4UXHA 1SGDI 2J9RA 2V1CC 1CT2I 1W4RA 4UXIA 2ARPF 1YTPA 3OVOA 5FUWA 3OXFA 1M8BA 2JW6A 3UGIA 1TGSI 1TOTA 2NU4I 5FUXA 2NU0I 1CHOI 1FYBA 1TURA 1CSOI 2N71A 1Z7KB 2NU1I 3OXGA 1CE3A 5EX3A 5FUVA 1N13A 2XRCA 3MEKA 3CXLA 1Y1BA 2ENNA 2SGDI 3BJIA 1CT0I 2GKTI 3TJQA 5FUYA 1U5KA 1KBEA 2J87A 3UEYA 4GI3C 3PDNA 1LR7A 3VDUA 4E1RA 1UUCA 2JXDA 2N52A 1Y8FA 2BUSA 2ENZA 3E59A 1X4SA 1SGQI 4JCVE 1IW4A 3RU0A 3HH2C 4UXJA 2L8EA 3KY9A 1YU6C 1W3SA 2LEOA 5DAEA 3FC3A 3SEKC 2V1CA 1XBTA 1V1IA 2GKVA 1OMTA 2KMQA 1HPTA 2NU3I 3OL0A 1KBFA 1UVGA 1SGEI 3UGLA 1PJUA 4A24A 1PPFI 3E2IA 3VDPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4SGB I;  1LR8 A;  2NU2 I;  2P6A C;  1TBQ R;  2QQD A;  2JYY A;  1OYV I;  2F3C I;  1CGI I;  3QTL D;  1NUB A;  1HDL A;  1MT1 A;  2N17 A;  2SGF I;  2KMP A;  1TIH A;  1DS2 I;  1SGR I;  1Y1C A;  1IY5 A;  1PCE A;  2JZM A;  2SGQ I;  2OVO A;  1M8C A;  1R0R I;  2M5X A;  2SGE I;  1KMA A;  1H0Z A;  2KMR A;  1SGP I;  2GKR I;  1CT4 I;  1SGN I;  2QQC A;  3SGB I;  2WCY A;  1HJA I;  1SGY I;  1TUS A;  2KCX A;  3B4V C;  3SGQ I;  1IY6 A;  1TBR R;  1CGJ I;  1LR9 A;  2ERW A;  2SGP I;  2B0U C;  1BUS A;  1DS3 I;  1BMO A;  5JHW C;  1UVF A;  1OMU A;  1AN1 I;  2KMO A;  4OVO A;  1OVO A;  2V53 A;  4HGU A;  1SGD I;  1CT2 I;  2ARP F;  1YTP A;  3OVO A;  1M8B A;  1TGS I;  2NU4 I;  2NU0 I;  1CHO I;  1FYB A;  1TUR A;  1CSO I;  2N71 A;  1Z7K B;  2NU1 I;  1CE3 A;  1N13 A;  2XRC A;  1Y1B A;  2SGD I;  2GKT I;  1CT0 I;  3TJQ A;  4GI3 C;  1LR7 A;  1UUC A;  2JXD A;  2N52 A;  2BUS A;  1SGQ I;  1IW4 A;  3HH2 C;  1YU6 C;  2LEO A;  5DAE A;  3SEK C;  2GKV A;  1OMT A;  2KMQ A;  1HPT A;  2NU3 I;  1UVG A;  1SGE I;  1PJU A;  1PPF I; 
#chains in the Genus database with same CATH topology
 4SGB I;  1PTQ A;  1NXU A;  1R79 A;  2GIV A;  2N1A B;  2ODD A;  5EX0 A;  3OXL A;  2LB7 A;  2JA1 A;  2OD1 A;  1FAQ A;  1TBN A;  4L9M A;  2E5R A;  5CCL A;  2Y0M A;  1LR8 A;  2NU2 I;  2P6A C;  1TBQ R;  2RC4 A;  2DB6 A;  2QQD A;  1ULM A;  1OYV I;  2JYY A;  2A20 A;  2F3C I;  1CGI I;  3QTL D;  1NUB A;  1HDL A;  1MT1 A;  2B8T A;  3UEJ A;  2N17 A;  1ULK A;  2KMP A;  2SGF I;  3VE5 A;  1TIH A;  1DS2 I;  1PTR A;  2FNF X;  1SGR I;  4FKD A;  1WKX A;  1Y1C A;  3TO9 A;  1HEV A;  2DIP A;  1IY5 A;  1PCE A;  2JZM A;  2SGQ I;  2YUU A;  2WGC A;  2OVO A;  1M8C A;  1R0R I;  2WVJ A;  3FSX A;  1XX6 A;  2M5X A;  1K7V A;  2SGE I;  2UZ3 A;  2LUY A;  1KMA A;  1P9Z A;  1X74 A;  1H0Z A;  1V1H A;  4B6D A;  2KMR A;  2QPO A;  1SGP I;  2CWG A;  3D00 A;  2GKR I;  1CT4 I;  1SGN I;  2QQC A;  2X52 A;  3SGB I;  3R5A A;  1Z2I A;  1HJA I;  2WCY A;  5HI7 A;  1SGY I;  4E1P A;  1TUS A;  2L7X A;  5E3P A;  2GVI A;  2KCX A;  3TOB A;  3UGD A;  2OU2 A;  2CJS C;  3B4V C;  3SGQ I;  1K7U A;  1IY6 A;  1XA6 A;  1TBR R;  1CGJ I;  2DKV A;  2ELI A;  1LR9 A;  2ERW A;  2SGP I;  2YQP A;  2QQE A;  5HQ8 A;  2ORW A;  2B0U C;  2ROW A;  5J8C A;  1K7T A;  2VRW B;  5CCM A;  1BUS A;  2W0T A;  1DS3 I;  1BMO A;  1TBO A;  3UFF A;  1UVF A;  5JHW C;  1OMU A;  1RFH A;  4DNC A;  1FY7 A;  2CWF A;  1VDD A;  3UOE A;  4AML A;  1AN1 I;  2PQ8 A;  2E73 A;  2KMO A;  2QQ0 A;  3QWP A;  4OVO A;  1P9G A;  2ORV A;  1FAR A;  1OVO A;  2V53 A;  2K9H A;  4HGU A;  4UXH A;  9WGA A;  2CWH A;  3R5B A;  1SGD I;  2J9R A;  1WGT A;  2V1C C;  1CT2 I;  1W4R A;  3R5D A;  4UXI A;  2X3T A;  2ARP F;  1YTP A;  3OVO A;  4WP4 A;  5FUW A;  3OXF A;  1M8B A;  3FSY A;  2JW6 A;  3UGI A;  1TGS I;  1TOT A;  2NU4 I;  2UVO A;  5FUX A;  1MJA A;  2NU0 I;  1CHO I;  2RIJ A;  1FYB A;  1Q9B A;  1TUR A;  1CSO I;  2N71 A;  1UHA A;  1Z7K B;  2NU1 I;  3OXG A;  3TO6 A;  1CE3 A;  1MJ9 A;  5EX3 A;  5FUV A;  1N13 A;  2OZU A;  4MPI A;  2XRC A;  3MEK A;  3CXL A;  1MJB A;  1Y1B A;  2ENN A;  2SGD I;  3BJI A;  1CT0 I;  2GKT I;  3TJQ A;  5FUY A;  1U5K A;  1KBE A;  2J87 A;  3UEY A;  4GI3 C;  5J8F A;  3PDN A;  1LR7 A;  3VDU A;  4E1R A;  1UUC A;  2JXD A;  2N52 A;  1Y8F A;  2BUS A;  2ENZ A;  3E59 A;  1X4S A;  1SGQ I;  4JCV E;  1IW4 A;  3RU0 A;  3HH2 C;  4UXJ A;  5E3Q A;  2L8E A;  3KY9 A;  1YU6 C;  5E3R A;  1W3S A;  2LEO A;  5DAE A;  1WGC A;  3FC3 A;  3SEK C;  2V1C A;  1ULN A;  1XBT A;  3GOX A;  3TO7 A;  1V1I A;  3R5C A;  2GKV A;  1OMT A;  2KMQ A;  3TOA A;  1HPT A;  2NU3 I;  7WGA A;  3OL0 A;  1KBF A;  1UVG A;  1SGE I;  3UGL A;  1PJU A;  3QAH A;  1S20 A;  4A24 A;  1PPF I;  3E2I A;  1WTJ A;  3VDP A; 
#chains in the Genus database with same CATH homology
 4SGB I;  1PTQ A;  1R79 A;  2N1A B;  2ODD A;  5EX0 A;  3OXL A;  2JA1 A;  2OD1 A;  1FAQ A;  1TBN A;  4L9M A;  2E5R A;  5CCL A;  1LR8 A;  2NU2 I;  2P6A C;  1TBQ R;  2DB6 A;  2QQD A;  2JYY A;  1OYV I;  2A20 A;  2F3C I;  1CGI I;  3QTL D;  1NUB A;  1HDL A;  1MT1 A;  2B8T A;  3UEJ A;  2N17 A;  2SGF I;  2KMP A;  3VE5 A;  1TIH A;  1DS2 I;  1PTR A;  2FNF X;  1SGR I;  4FKD A;  1Y1C A;  2DIP A;  1IY5 A;  1PCE A;  2JZM A;  2SGQ I;  2YUU A;  2OVO A;  1M8C A;  1R0R I;  2WVJ A;  1XX6 A;  2M5X A;  2SGE I;  2UZ3 A;  2LUY A;  1KMA A;  1X74 A;  1H0Z A;  1V1H A;  4B6D A;  2KMR A;  2QPO A;  1SGP I;  3D00 A;  2GKR I;  1CT4 I;  1SGN I;  2QQC A;  3SGB I;  2WCY A;  1HJA I;  5HI7 A;  1SGY I;  4E1P A;  1TUS A;  2L7X A;  2GVI A;  2KCX A;  3UGD A;  2CJS C;  3B4V C;  3SGQ I;  1IY6 A;  1XA6 A;  1TBR R;  1CGJ I;  2ELI A;  1LR9 A;  2ERW A;  2SGP I;  2YQP A;  2QQE A;  5HQ8 A;  2ORW A;  2B0U C;  2ROW A;  3GOX A;  2VRW B;  5CCM A;  1BUS A;  2W0T A;  1DS3 I;  1BMO A;  1TBO A;  3UFF A;  1UVF A;  5JHW C;  1OMU A;  1RFH A;  1VDD A;  1AN1 I;  2E73 A;  2KMO A;  2QQ0 A;  3QWP A;  4OVO A;  2ORV A;  1FAR A;  1OVO A;  2V53 A;  2K9H A;  4HGU A;  4UXH A;  1SGD I;  2J9R A;  2V1C C;  1CT2 I;  1W4R A;  4UXI A;  2ARP F;  1YTP A;  3OVO A;  5FUW A;  3OXF A;  1M8B A;  2JW6 A;  3UGI A;  1TGS I;  1TOT A;  2NU4 I;  5FUX A;  2NU0 I;  1CHO I;  1FYB A;  1TUR A;  1CSO I;  2N71 A;  1Z7K B;  2NU1 I;  3OXG A;  1CE3 A;  5EX3 A;  5FUV A;  1N13 A;  2XRC A;  3MEK A;  3CXL A;  1Y1B A;  2ENN A;  2SGD I;  3BJI A;  1CT0 I;  2GKT I;  3TJQ A;  5FUY A;  1U5K A;  1KBE A;  2J87 A;  3UEY A;  4GI3 C;  3PDN A;  1LR7 A;  3VDU A;  4E1R A;  1UUC A;  2JXD A;  2N52 A;  1Y8F A;  2BUS A;  2ENZ A;  3E59 A;  1X4S A;  1SGQ I;  4JCV E;  1IW4 A;  3RU0 A;  3HH2 C;  4UXJ A;  2L8E A;  3KY9 A;  1YU6 C;  1W3S A;  2LEO A;  5DAE A;  3FC3 A;  3SEK C;  2V1C A;  1XBT A;  1V1I A;  2GKV A;  1OMT A;  2KMQ A;  1HPT A;  2NU3 I;  3OL0 A;  1KBF A;  1UVG A;  1SGE I;  3UGL A;  1PJU A;  4A24 A;  1PPF I;  3E2I A;  3VDP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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