1R0RI

1.1 angstrom resolution structure of the complex between the protein inhibitor, omtky3, and the serine protease, subtilisin carlsberg
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
51
structure length
51
Chain Sequence
VDCSEYPKPACTLEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
publication title Structure and energetics of protein-protein interactions: the role of conformational heterogeneity in OMTKY3 binding to serine proteases
pubmed doi rcsb
molecule keywords subtilisin carlsberg
total genus 14
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 2003-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1r0rI00
2GKTI 2KMRA 1BUSA 1DS3I 5JHWC 1LR7A 2V53A 3SGBI 2NU0I 2QQDA 1DS2I 1CGII 2ARPF 1BMOA 4OVOA 2GKRI 1SGRI 4GI3C 1CT4I 4HGUA 1FYBA 1OMUA 2NU2I 1YU6C 1LR8A 2F3CI 1Z7KB 2KMQA 3HH2C 1R0RI 2BUSA 1CSOI 1OYVI 4SGBI 1TGSI 2LEOA 1TBQR 2JXDA 1PJUA 1TUSA 2KMOA 1SGNI 2XRCA 1HPTA 1TBRR 2B0UC 1CE3A 1SGQI 1Y1CA 3QTLD 3TJQA 1TIHA 1UVFA 2GKVA 1OMTA 1CT0I 2M5XA 2SGQI 2SGDI 1MT1A 1M8CA 5DAEA 3OVOA 1IW4A 2WCYA 1H0ZA 1IY6A 2N71A 1SGDI 1UUCA 2N17A 1HDLA 2JZMA 3B4VC 1SGEI 1M8BA 2KCXA 2N52A 1SGPI 2SGEI 1NUBA 1UVGA 2NU3I 1PCEA 1CGJI 1OVOA 1SGYI 2NU4I 1YTPA 1CT2I 2SGPI 1KMAA 2QQCA 2P6AC 1HJAI 2ERWA 1TURA 1Y1BA 1CHOI 2OVOA 2JYYA 1N13A 3SEKC 2NU1I 1IY5A 1PPFI 3SGQI 2KMPA 2SGFI 1LR9A 1AN1I
chains in the Genus database with same CATH superfamily
2GKTI 2QQ0A 2N1AB 2KMRA 2OD1A 3VDUA 7WGAA 1FAQA 1BUSA 2V1CC 2RIJA 4DNCA 3TOBA 1KBEA 2FNFX 1DS3I 2ELIA 1LR7A 3RU0A 2OZUA 3UGLA 1WKXA 2UZ3A 2V53A 3SGBI 5JHWC 2NU0I 1P9ZA 1VDDA 2QQDA 2X52A 3CXLA 2CWFA 2PQ8A 1V1HA 5E3RA 1DS2I 1CGII 2ARPF 3OXLA 2QPOA 1BMOA 2VRWB 4OVOA 2GKRI 1SGRI 2LB7A 1PTQA 4GI3C 1CT4I 4HGUA 3MEKA 3UEJA 1OMUA 2NU2I 2V1CA 1FYBA 1YU6C 1LR8A 3TOAA 3UFFA 2GVIA 4E1PA 2OU2A 2F3CI 2UVOA 3QWPA 1Z7KB 1WGTA 2ORWA 3R5BA 4JCVE 4FKDA 4UXJA 2KMQA 1PTRA 1X4SA 1V1IA 3BJIA 4MPIA 5FUWA 3KY9A 5J8FA 1RFHA 1R0RI 3HH2C 3E2IA 2RC4A 3VE5A 2BUSA 1Q9BA 3OXFA 5CCLA 1CSOI 1OYVI 5J8CA 4SGBI 1TGSI 1MJAA 4WP4A 1Z2IA 2LEOA 3R5DA 1TBQR 2JXDA 1PJUA 1TUSA 4AMLA 3TO9A 5CCMA 2A20A 1NXUA 2KMOA 1SGNI 2XRCA 2YUUA 1HPTA 1TBRR 2ENZA 2B0UC 1XX6A 1TBNA 2ROWA 2ENNA 3FSXA 1UHAA 1SGQI 2QQEA 5EX0A 5FUYA 1Y1CA 1CE3A 3QTLD 3TJQA 1R79A 1Y8FA 1S20A 1WTJA 3QAHA 2K9HA 1TIHA 1UVFA 2GKVA 4A24A 1OMTA 3UGDA 5FUXA 1U5KA 1CT0I 2M5XA 2E5RA 2SGQI 3TO6A 3UEYA 1FARA 2SGDI 2E73A 1MT1A 2WGCA 1M8CA 5DAEA 2JA1A 1TBOA 3OVOA 1IW4A 1W3SA 2J9RA 2WCYA 1H0ZA 2Y0MA 5FUVA 2N71A 1SGDI 3R5AA 1IY6A 1TOTA 2CWGA 1ULMA 1UUCA 2N17A 1HDLA 2JZMA 1K7UA 1MJBA 1SGEI 3B4VC 2WVJA 2GIVA 1HEVA 1M8BA 5EX3A 2YQPA 1X74A 1KBFA 2KCXA 2LUYA 3OXGA 2CWHA 2L7XA 2N52A 2JW6A 1SGPI 2SGEI 1NUBA 1K7VA 1UVGA 1PCEA 1CGJI 2NU3I 1OVOA 5E3PA 2ORVA 3D00A 2W0TA 5E3QA 1SGYI 2NU4I 1ULKA 1YTPA 3UOEA 1CT2I 2SGPI 1KMAA 2QQCA 1MJ9A 2CJSC 2J87A 2P6AC 4B6DA 1HJAI 4E1RA 1WGCA 2ERWA 5HI7A 1TURA 1Y1BA 3FC3A 3R5CA 3TO7A 4L9MA 1CHOI 2OVOA 2X3TA 5HQ8A 4UXHA 2JYYA 2DKVA 1FY7A 2DB6A 1N13A 1XBTA 3E59A 1K7TA 3SEKC 2NU1I 1IY5A 1PPFI 3OL0A 2DIPA 3SGQI 3PDNA 1P9GA 4UXIA 9WGAA 3UGIA 2B8TA 1ULNA 2KMPA 2L8EA 1W4RA 2ODDA 3GOXA 1XA6A 2SGFI 1LR9A 3FSYA 1AN1I 3VDPA
chains in the Genus database with same CATH topology
2GKTI 2QQ0A 2N1AB 2KMRA 2OD1A 3VDUA 1FAQA 1BUSA 2V1CC 1KBEA 2FNFX 1DS3I 2ELIA 1LR7A 3RU0A 5JHWC 3UGLA 2UZ3A 2V53A 3SGBI 2NU0I 1VDDA 2QQDA 3CXLA 1V1HA 1DS2I 1CGII 2ARPF 3OXLA 2QPOA 1BMOA 2VRWB 4OVOA 2GKRI 1SGRI 4GI3C 1PTQA 1CT4I 4HGUA 3MEKA 3UEJA 1OMUA 2NU2I 2V1CA 1FYBA 1YU6C 1LR8A 3UFFA 2GVIA 4E1PA 2F3CI 3QWPA 1Z7KB 2ORWA 4JCVE 4FKDA 4UXJA 2KMQA 1PTRA 1X4SA 1V1IA 3BJIA 5FUWA 3KY9A 1RFHA 1R0RI 3HH2C 3E2IA 3VE5A 2BUSA 5CCLA 3OXFA 1CSOI 1OYVI 4SGBI 1TGSI 2LEOA 1TBQR 2JXDA 1PJUA 1TUSA 5CCMA 2A20A 2KMOA 1SGNI 2XRCA 2YUUA 1HPTA 1TBRR 2ENZA 2B0UC 1XX6A 1TBNA 2ROWA 2ENNA 1CE3A 1SGQI 2QQEA 5EX0A 5FUYA 1Y1CA 3QTLD 3TJQA 1R79A 1Y8FA 2K9HA 1TIHA 1UVFA 2GKVA 4A24A 1OMTA 3UGDA 1U5KA 1CT0I 2M5XA 2E5RA 2SGQI 3UEYA 1FARA 2SGDI 2E73A 1MT1A 1M8CA 5DAEA 2JA1A 1TBOA 3OVOA 1IW4A 1W3SA 2J9RA 2WCYA 1H0ZA 5FUVA 2N71A 1SGDI 1IY6A 1TOTA 1UUCA 2N17A 1HDLA 2JZMA 3B4VC 1SGEI 2WVJA 1M8BA 5EX3A 2YQPA 1X74A 1KBFA 2KCXA 2LUYA 3OXGA 2L7XA 2N52A 2JW6A 1SGPI 2SGEI 1NUBA 5FUXA 1UVGA 1PCEA 1CGJI 2NU3I 1OVOA 5HQ8A 2ORVA 3D00A 2W0TA 1SGYI 2NU4I 1YTPA 1CT2I 2SGPI 1KMAA 2QQCA 2CJSC 2J87A 2P6AC 4B6DA 1HJAI 4E1RA 2ERWA 5HI7A 1TURA 1Y1BA 3FC3A 4L9MA 1CHOI 2OVOA 4UXHA 2JYYA 2DB6A 1N13A 1XBTA 3E59A 3SEKC 2NU1I 1IY5A 1PPFI 3OL0A 2DIPA 3SGQI 3PDNA 4UXIA 3UGIA 2B8TA 2KMPA 2L8EA 1W4RA 2ODDA 3GOXA 1XA6A 2SGFI 1LR9A 1AN1I 3VDPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GKT I;  2KMR A;  1BUS A;  1DS3 I;  5JHW C;  1LR7 A;  2V53 A;  3SGB I;  2NU0 I;  2QQD A;  1DS2 I;  1CGI I;  2ARP F;  1BMO A;  4OVO A;  2GKR I;  1SGR I;  4GI3 C;  1CT4 I;  4HGU A;  1FYB A;  1OMU A;  2NU2 I;  1YU6 C;  1LR8 A;  2F3C I;  1Z7K B;  2KMQ A;  3HH2 C;  1R0R I;  2BUS A;  1CSO I;  1OYV I;  4SGB I;  1TGS I;  2LEO A;  1TBQ R;  2JXD A;  1PJU A;  1TUS A;  2KMO A;  1SGN I;  2XRC A;  1HPT A;  1TBR R;  2B0U C;  1CE3 A;  1SGQ I;  1Y1C A;  3QTL D;  3TJQ A;  1TIH A;  1UVF A;  2GKV A;  1OMT A;  1CT0 I;  2M5X A;  2SGQ I;  2SGD I;  1MT1 A;  1M8C A;  5DAE A;  3OVO A;  1IW4 A;  2WCY A;  1H0Z A;  1IY6 A;  2N71 A;  1SGD I;  1UUC A;  2N17 A;  1HDL A;  2JZM A;  3B4V C;  1SGE I;  1M8B A;  2KCX A;  2N52 A;  1SGP I;  2SGE I;  1NUB A;  1UVG A;  2NU3 I;  1PCE A;  1CGJ I;  1OVO A;  1SGY I;  2NU4 I;  1YTP A;  1CT2 I;  2SGP I;  1KMA A;  2QQC A;  2P6A C;  1HJA I;  2ERW A;  1TUR A;  1Y1B A;  1CHO I;  2OVO A;  2JYY A;  1N13 A;  3SEK C;  2NU1 I;  1IY5 A;  1PPF I;  3SGQ I;  2KMP A;  2SGF I;  1LR9 A;  1AN1 I; 
#chains in the Genus database with same CATH topology
 2GKT I;  2QQ0 A;  2N1A B;  2KMR A;  2OD1 A;  3VDU A;  7WGA A;  1FAQ A;  1BUS A;  2V1C C;  2RIJ A;  4DNC A;  3TOB A;  1KBE A;  2FNF X;  1DS3 I;  2ELI A;  1LR7 A;  3RU0 A;  2OZU A;  3UGL A;  1WKX A;  2UZ3 A;  2V53 A;  3SGB I;  5JHW C;  2NU0 I;  1P9Z A;  1VDD A;  2QQD A;  2X52 A;  3CXL A;  2CWF A;  2PQ8 A;  1V1H A;  5E3R A;  1DS2 I;  1CGI I;  2ARP F;  3OXL A;  2QPO A;  1BMO A;  2VRW B;  4OVO A;  2GKR I;  1SGR I;  2LB7 A;  1PTQ A;  4GI3 C;  1CT4 I;  4HGU A;  3MEK A;  3UEJ A;  1OMU A;  2NU2 I;  2V1C A;  1FYB A;  1YU6 C;  1LR8 A;  3TOA A;  3UFF A;  2GVI A;  4E1P A;  2OU2 A;  2F3C I;  2UVO A;  3QWP A;  1Z7K B;  1WGT A;  2ORW A;  3R5B A;  4JCV E;  4FKD A;  4UXJ A;  2KMQ A;  1PTR A;  1X4S A;  1V1I A;  3BJI A;  4MPI A;  5FUW A;  3KY9 A;  5J8F A;  1RFH A;  1R0R I;  3HH2 C;  3E2I A;  2RC4 A;  3VE5 A;  2BUS A;  1Q9B A;  3OXF A;  5CCL A;  1CSO I;  1OYV I;  5J8C A;  4SGB I;  1TGS I;  1MJA A;  4WP4 A;  1Z2I A;  2LEO A;  3R5D A;  1TBQ R;  2JXD A;  1PJU A;  1TUS A;  4AML A;  3TO9 A;  5CCM A;  2A20 A;  1NXU A;  2KMO A;  1SGN I;  2XRC A;  2YUU A;  1HPT A;  1TBR R;  2ENZ A;  2B0U C;  1XX6 A;  1TBN A;  2ROW A;  2ENN A;  3FSX A;  1UHA A;  1SGQ I;  2QQE A;  5EX0 A;  5FUY A;  1Y1C A;  1CE3 A;  3QTL D;  3TJQ A;  1R79 A;  1Y8F A;  1S20 A;  1WTJ A;  3QAH A;  2K9H A;  1TIH A;  1UVF A;  2GKV A;  4A24 A;  1OMT A;  3UGD A;  5FUX A;  1U5K A;  1CT0 I;  2M5X A;  2E5R A;  2SGQ I;  3TO6 A;  3UEY A;  1FAR A;  2SGD I;  2E73 A;  1MT1 A;  2WGC A;  1M8C A;  5DAE A;  2JA1 A;  1TBO A;  3OVO A;  1IW4 A;  1W3S A;  2J9R A;  2WCY A;  1H0Z A;  2Y0M A;  5FUV A;  2N71 A;  1SGD I;  3R5A A;  1IY6 A;  1TOT A;  2CWG A;  1ULM A;  1UUC A;  2N17 A;  1HDL A;  2JZM A;  1K7U A;  1MJB A;  1SGE I;  3B4V C;  2WVJ A;  2GIV A;  1HEV A;  1M8B A;  5EX3 A;  2YQP A;  1X74 A;  1KBF A;  2KCX A;  2LUY A;  3OXG A;  2CWH A;  2L7X A;  2N52 A;  2JW6 A;  1SGP I;  2SGE I;  1NUB A;  1K7V A;  1UVG A;  1PCE A;  1CGJ I;  2NU3 I;  1OVO A;  5E3P A;  2ORV A;  3D00 A;  2W0T A;  5E3Q A;  1SGY I;  2NU4 I;  1ULK A;  1YTP A;  3UOE A;  1CT2 I;  2SGP I;  1KMA A;  2QQC A;  1MJ9 A;  2CJS C;  2J87 A;  2P6A C;  4B6D A;  1HJA I;  4E1R A;  1WGC A;  2ERW A;  5HI7 A;  1TUR A;  1Y1B A;  3FC3 A;  3R5C A;  3TO7 A;  4L9M A;  1CHO I;  2OVO A;  2X3T A;  5HQ8 A;  4UXH A;  2JYY A;  2DKV A;  1FY7 A;  2DB6 A;  1N13 A;  1XBT A;  3E59 A;  1K7T A;  3SEK C;  2NU1 I;  1IY5 A;  1PPF I;  3OL0 A;  2DIP A;  3SGQ I;  3PDN A;  1P9G A;  4UXI A;  9WGA A;  3UGI A;  2B8T A;  1ULN A;  2KMP A;  2L8E A;  1W4R A;  2ODD A;  3GOX A;  1XA6 A;  2SGF I;  1LR9 A;  3FSY A;  1AN1 I;  3VDP A; 
#chains in the Genus database with same CATH homology
 2GKT I;  2QQ0 A;  2N1A B;  2KMR A;  2OD1 A;  3VDU A;  1FAQ A;  1BUS A;  2V1C C;  1KBE A;  2FNF X;  1DS3 I;  2ELI A;  1LR7 A;  3RU0 A;  5JHW C;  3UGL A;  2UZ3 A;  2V53 A;  3SGB I;  2NU0 I;  1VDD A;  2QQD A;  3CXL A;  1V1H A;  1DS2 I;  1CGI I;  2ARP F;  3OXL A;  2QPO A;  1BMO A;  2VRW B;  4OVO A;  2GKR I;  1SGR I;  4GI3 C;  1PTQ A;  1CT4 I;  4HGU A;  3MEK A;  3UEJ A;  1OMU A;  2NU2 I;  2V1C A;  1FYB A;  1YU6 C;  1LR8 A;  3UFF A;  2GVI A;  4E1P A;  2F3C I;  3QWP A;  1Z7K B;  2ORW A;  4JCV E;  4FKD A;  4UXJ A;  2KMQ A;  1PTR A;  1X4S A;  1V1I A;  3BJI A;  5FUW A;  3KY9 A;  1RFH A;  1R0R I;  3HH2 C;  3E2I A;  3VE5 A;  2BUS A;  5CCL A;  3OXF A;  1CSO I;  1OYV I;  4SGB I;  1TGS I;  2LEO A;  1TBQ R;  2JXD A;  1PJU A;  1TUS A;  5CCM A;  2A20 A;  2KMO A;  1SGN I;  2XRC A;  2YUU A;  1HPT A;  1TBR R;  2ENZ A;  2B0U C;  1XX6 A;  1TBN A;  2ROW A;  2ENN A;  1CE3 A;  1SGQ I;  2QQE A;  5EX0 A;  5FUY A;  1Y1C A;  3QTL D;  3TJQ A;  1R79 A;  1Y8F A;  2K9H A;  1TIH A;  1UVF A;  2GKV A;  4A24 A;  1OMT A;  3UGD A;  1U5K A;  1CT0 I;  2M5X A;  2E5R A;  2SGQ I;  3UEY A;  1FAR A;  2SGD I;  2E73 A;  1MT1 A;  1M8C A;  5DAE A;  2JA1 A;  1TBO A;  3OVO A;  1IW4 A;  1W3S A;  2J9R A;  2WCY A;  1H0Z A;  5FUV A;  2N71 A;  1SGD I;  1IY6 A;  1TOT A;  1UUC A;  2N17 A;  1HDL A;  2JZM A;  3B4V C;  1SGE I;  2WVJ A;  1M8B A;  5EX3 A;  2YQP A;  1X74 A;  1KBF A;  2KCX A;  2LUY A;  3OXG A;  2L7X A;  2N52 A;  2JW6 A;  1SGP I;  2SGE I;  1NUB A;  5FUX A;  1UVG A;  1PCE A;  1CGJ I;  2NU3 I;  1OVO A;  5HQ8 A;  2ORV A;  3D00 A;  2W0T A;  1SGY I;  2NU4 I;  1YTP A;  1CT2 I;  2SGP I;  1KMA A;  2QQC A;  2CJS C;  2J87 A;  2P6A C;  4B6D A;  1HJA I;  4E1R A;  2ERW A;  5HI7 A;  1TUR A;  1Y1B A;  3FC3 A;  4L9M A;  1CHO I;  2OVO A;  4UXH A;  2JYY A;  2DB6 A;  1N13 A;  1XBT A;  3E59 A;  3SEK C;  2NU1 I;  1IY5 A;  1PPF I;  3OL0 A;  2DIP A;  3SGQ I;  3PDN A;  4UXI A;  3UGI A;  2B8T A;  2KMP A;  2L8E A;  1W4R A;  2ODD A;  3GOX A;  1XA6 A;  2SGF I;  1LR9 A;  1AN1 I;  3VDP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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