1SGEI

Glu 18 variant of turkey ovomucoid inhibitor third domain complexed with streptomyces griseus proteinase b at ph 6.5
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
51
structure length
51
Chain Sequence
VDCSEYPKPACTEEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pHs
rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Meleagris gallopavo
molecule keywords Streptogrisin B
total genus 13
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 1999-03-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1sgeI00
1HPTA 1TUSA 2JXDA 2QQCA 1CT4I 1LR9A 3SEKC 2NU3I 2V53A 1BUSA 1R0RI 1LR8A 1Y1CA 3OVOA 3B4VC 1TBRR 1SGEI 2KMRA 1SGYI 4SGBI 1SGDI 2GKVA 3TJQA 1TGSI 1CE3A 1UVFA 2XRCA 4OVOA 1SGQI 1TBQR 2P6AC 1YTPA 1HDLA 1AN1I 1CGJI 2NU2I 2LEOA 2SGDI 1NUBA 2F3CI 2GKRI 1H0ZA 2NU4I 1LR7A 2GKTI 1SGPI 1CGII 1TURA 1BMOA 1N13A 1IY6A 1M8CA 3QTLD 1PJUA 2BUSA 2JYYA 5JHWC 2OVOA 2M5XA 1M8BA 1FYBA 1TIHA 1Z7KB 2ERWA 2NU1I 1DS3I 1YU6C 2KMPA 2SGEI 1MT1A 2QQDA 2B0UC 5DAEA 2NU0I 1CT2I 1OMUA 1UVGA 2N71A 1OMTA 1SGNI 3SGQI 1PPFI 1IW4A 1DS2I 4HGUA 2SGQI 1CT0I 1HJAI 2N52A 2JZMA 1OVOA 1KMAA 1IY5A 2KMQA 2SGFI 1SGRI 3HH2C 1OYVI 2WCYA 1Y1BA 2N17A 2ARPF 2KMOA 1PCEA 2SGPI 1CSOI 4GI3C 3SGBI 1UUCA 1CHOI 2KCXA
chains in the Genus database with same CATH superfamily
1HPTA 2ENNA 3VDPA 4UXIA 2W0TA 2ORVA 1TUSA 1Q9BA 1NXUA 1FAQA 2V1CC 2JXDA 2QQCA 1CT4I 3TOAA 2RIJA 1LR9A 4AMLA 2WVJA 2OD1A 1W3SA 2J9RA 4JCVE 4A24A 5FUWA 3FSXA 3R5BA 3SEKC 2NU3I 2V53A 5FUXA 5EX0A 5E3QA 1PTRA 1BUSA 3UEYA 1R0RI 1LR8A 3UGDA 3R5CA 5CCMA 2A20A 2LUYA 4UXJA 1Y1CA 3OVOA 3B4VC 1TBRR 4DNCA 5HQ8A 1SGEI 2KMRA 4UXHA 1SGYI 4SGBI 1SGDI 2GKVA 2ROWA 3QAHA 3TJQA 2PQ8A 1TGSI 1CE3A 3UOEA 3CXLA 2K9HA 1UVFA 2CJSC 5J8CA 2XRCA 4OVOA 1SGQI 1MJAA 2JW6A 2OU2A 5EX3A 1MJ9A 1TBQR 5E3RA 2P6AC 1TBOA 1YTPA 3R5AA 1AN1I 1CGJI 1VDDA 3UGLA 1HDLA 1KBFA 5FUYA 2NU2I 1ULKA 2LEOA 2SGDI 1NUBA 1ULMA 2F3CI 2GKRI 2L7XA 2L8EA 2ODDA 4FKDA 3TO6A 1H0ZA 2CWFA 2GKTI 1LR7A 2GVIA 2NU4I 3D00A 1SGPI 3UEJA 7WGAA 2N1AB 3RU0A 2VRWB 2B8TA 1CGII 1TURA 1BMOA 2OZUA 1N13A 1WKXA 1X4SA 1IY6A 1K7TA 1M8CA 1TBNA 2J87A 3QTLD 3R5DA 1PJUA 1XA6A 2CWGA 2X3TA 1FY7A 2YUUA 2ELIA 2BUSA 2JYYA 3OXFA 5JHWC 1ULNA 2ORWA 3KY9A 2OVOA 3MEKA 1HEVA 2M5XA 1V1IA 1M8BA 1WTJA 1FARA 4E1PA 1TIHA 1FYBA 2GIVA 1P9ZA 1Z7KB 2ERWA 2ENZA 3E59A 2NU1I 1DS3I 2WGCA 1XX6A 3TO7A 3PDNA 1YU6C 2KMPA 2SGEI 2Y0MA 1MT1A 1P9GA 2B0UC 2QQDA 1W4RA 5DAEA 1CT2I 2NU0I 1OMUA 1UVGA 1X74A 2N71A 4MPIA 1OMTA 2JA1A 4B6DA 2UVOA 1K7UA 1WGTA 1SGNI 1TOTA 2LB7A 3SGQI 1PPFI 1PTQA 3VDUA 3UFFA 3BJIA 5FUVA 9WGAA 1IW4A 1DS2I 3VE5A 4HGUA 2DIPA 2SGQI 1MJBA 2DKVA 3GOXA 1CT0I 1HJAI 3FC3A 3TO9A 1KBEA 2N52A 1U5KA 2RC4A 2JZMA 1OVOA 1KMAA 1RFHA 3OXLA 2QQEA 3OXGA 1WGCA 1XBTA 2UZ3A 2V1CA 5E3PA 5J8FA 1IY5A 2QQ0A 3TOBA 3E2IA 1UHAA 3QWPA 2KMQA 2SGFI 2QPOA 5HI7A 1SGRI 1K7VA 3HH2C 4L9MA 3OL0A 4E1RA 1OYVI 2YQPA 1R79A 2X52A 2DB6A 2WCYA 3UGIA 1Y1BA 2FNFX 1Y8FA 1Z2IA 2CWHA 3FSYA 2E5RA 2N17A 2ARPF 2KMOA 4WP4A 1V1HA 1PCEA 2SGPI 1CSOI 4GI3C 3SGBI 5CCLA 1S20A 1UUCA 1CHOI 2KCXA 2E73A
chains in the Genus database with same CATH topology
1HPTA 2ENNA 3VDPA 4UXIA 2W0TA 2ORVA 1TUSA 1FAQA 2V1CC 2JXDA 2QQCA 1CT4I 1LR9A 2WVJA 2OD1A 1W3SA 2J9RA 4JCVE 4A24A 5FUWA 3SEKC 2NU3I 2V53A 5FUXA 5EX0A 1PTRA 1BUSA 3UEYA 1R0RI 1LR8A 3UGDA 5CCMA 2A20A 2LUYA 4UXJA 1Y1CA 3OVOA 3B4VC 1TBRR 1SGEI 2KMRA 4UXHA 1SGYI 4SGBI 1SGDI 2GKVA 2ROWA 3TJQA 1TGSI 1CE3A 3CXLA 2K9HA 1UVFA 2CJSC 2XRCA 4OVOA 1SGQI 2JW6A 5EX3A 1TBQR 2P6AC 1TBOA 1YTPA 1HDLA 1AN1I 1CGJI 1VDDA 3UGLA 1KBFA 5FUYA 2NU2I 2LEOA 2SGDI 1NUBA 2F3CI 2L7XA 2GKRI 2L8EA 2ODDA 4FKDA 5HQ8A 1H0ZA 2GKTI 1LR7A 2GVIA 2NU4I 3D00A 1SGPI 3UEJA 2N1AB 3RU0A 2VRWB 2B8TA 1CGII 1TURA 1BMOA 1N13A 1X4SA 1IY6A 1M8CA 1TBNA 2J87A 3QTLD 1PJUA 1XA6A 2YUUA 2ELIA 2BUSA 2JYYA 3OXFA 5JHWC 2ORWA 3KY9A 2OVOA 3MEKA 2M5XA 1V1IA 1M8BA 1FARA 4E1PA 1TIHA 1FYBA 1Z7KB 2ERWA 2ENZA 3E59A 2NU1I 1DS3I 1XX6A 3PDNA 1YU6C 2KMPA 2SGEI 1MT1A 2QQDA 2B0UC 1W4RA 5DAEA 1CT2I 2NU0I 1OMUA 1UVGA 1X74A 2N71A 1OMTA 2JA1A 4B6DA 1SGNI 1TOTA 3SGQI 1PPFI 1PTQA 3VDUA 3UFFA 3BJIA 5FUVA 1IW4A 1DS2I 3VE5A 4HGUA 2DIPA 2SGQI 3GOXA 1CT0I 1HJAI 3FC3A 1KBEA 2N52A 1U5KA 2JZMA 1OVOA 1KMAA 1RFHA 3OXLA 2QQEA 3OXGA 2V1CA 1XBTA 2UZ3A 1IY5A 2QQ0A 3E2IA 3QWPA 5HI7A 2KMQA 2SGFI 2QPOA 1SGRI 3HH2C 4L9MA 3OL0A 4E1RA 1OYVI 2YQPA 1R79A 2DB6A 2WCYA 3UGIA 1Y1BA 2FNFX 1Y8FA 2E5RA 2N17A 2ARPF 2KMOA 1V1HA 1PCEA 2SGPI 1CSOI 4GI3C 3SGBI 5CCLA 1UUCA 1CHOI 2KCXA 2E73A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HPT A;  1TUS A;  2JXD A;  2QQC A;  1CT4 I;  1LR9 A;  3SEK C;  2NU3 I;  2V53 A;  1BUS A;  1R0R I;  1LR8 A;  1Y1C A;  3OVO A;  3B4V C;  1TBR R;  1SGE I;  2KMR A;  1SGY I;  4SGB I;  1SGD I;  2GKV A;  3TJQ A;  1TGS I;  1CE3 A;  1UVF A;  2XRC A;  4OVO A;  1SGQ I;  1TBQ R;  2P6A C;  1YTP A;  1HDL A;  1AN1 I;  1CGJ I;  2NU2 I;  2LEO A;  2SGD I;  1NUB A;  2F3C I;  2GKR I;  1H0Z A;  2NU4 I;  1LR7 A;  2GKT I;  1SGP I;  1CGI I;  1TUR A;  1BMO A;  1N13 A;  1IY6 A;  1M8C A;  3QTL D;  1PJU A;  2BUS A;  2JYY A;  5JHW C;  2OVO A;  2M5X A;  1M8B A;  1FYB A;  1TIH A;  1Z7K B;  2ERW A;  2NU1 I;  1DS3 I;  1YU6 C;  2KMP A;  2SGE I;  1MT1 A;  2QQD A;  2B0U C;  5DAE A;  2NU0 I;  1CT2 I;  1OMU A;  1UVG A;  2N71 A;  1OMT A;  1SGN I;  3SGQ I;  1PPF I;  1IW4 A;  1DS2 I;  4HGU A;  2SGQ I;  1CT0 I;  1HJA I;  2N52 A;  2JZM A;  1OVO A;  1KMA A;  1IY5 A;  2KMQ A;  2SGF I;  1SGR I;  3HH2 C;  1OYV I;  2WCY A;  1Y1B A;  2N17 A;  2ARP F;  2KMO A;  1PCE A;  2SGP I;  1CSO I;  4GI3 C;  3SGB I;  1UUC A;  1CHO I;  2KCX A; 
#chains in the Genus database with same CATH topology
 1HPT A;  2ENN A;  3VDP A;  4UXI A;  2W0T A;  2ORV A;  1TUS A;  1Q9B A;  1NXU A;  1FAQ A;  2V1C C;  2JXD A;  2QQC A;  1CT4 I;  3TOA A;  2RIJ A;  1LR9 A;  4AML A;  2WVJ A;  2OD1 A;  1W3S A;  2J9R A;  4JCV E;  4A24 A;  5FUW A;  3FSX A;  3R5B A;  3SEK C;  2NU3 I;  2V53 A;  5FUX A;  5EX0 A;  5E3Q A;  1PTR A;  1BUS A;  3UEY A;  1R0R I;  1LR8 A;  3UGD A;  3R5C A;  5CCM A;  2A20 A;  2LUY A;  4UXJ A;  1Y1C A;  3OVO A;  3B4V C;  1TBR R;  4DNC A;  5HQ8 A;  1SGE I;  2KMR A;  4UXH A;  1SGY I;  4SGB I;  1SGD I;  2GKV A;  2ROW A;  3QAH A;  3TJQ A;  2PQ8 A;  1TGS I;  1CE3 A;  3UOE A;  3CXL A;  2K9H A;  1UVF A;  2CJS C;  5J8C A;  2XRC A;  4OVO A;  1SGQ I;  1MJA A;  2JW6 A;  2OU2 A;  5EX3 A;  1MJ9 A;  1TBQ R;  5E3R A;  2P6A C;  1TBO A;  1YTP A;  3R5A A;  1AN1 I;  1CGJ I;  1VDD A;  3UGL A;  1HDL A;  1KBF A;  5FUY A;  2NU2 I;  1ULK A;  2LEO A;  2SGD I;  1NUB A;  1ULM A;  2F3C I;  2GKR I;  2L7X A;  2L8E A;  2ODD A;  4FKD A;  3TO6 A;  1H0Z A;  2CWF A;  2GKT I;  1LR7 A;  2GVI A;  2NU4 I;  3D00 A;  1SGP I;  3UEJ A;  7WGA A;  2N1A B;  3RU0 A;  2VRW B;  2B8T A;  1CGI I;  1TUR A;  1BMO A;  2OZU A;  1N13 A;  1WKX A;  1X4S A;  1IY6 A;  1K7T A;  1M8C A;  1TBN A;  2J87 A;  3QTL D;  3R5D A;  1PJU A;  1XA6 A;  2CWG A;  2X3T A;  1FY7 A;  2YUU A;  2ELI A;  2BUS A;  2JYY A;  3OXF A;  5JHW C;  1ULN A;  2ORW A;  3KY9 A;  2OVO A;  3MEK A;  1HEV A;  2M5X A;  1V1I A;  1M8B A;  1WTJ A;  1FAR A;  4E1P A;  1TIH A;  1FYB A;  2GIV A;  1P9Z A;  1Z7K B;  2ERW A;  2ENZ A;  3E59 A;  2NU1 I;  1DS3 I;  2WGC A;  1XX6 A;  3TO7 A;  3PDN A;  1YU6 C;  2KMP A;  2SGE I;  2Y0M A;  1MT1 A;  1P9G A;  2B0U C;  2QQD A;  1W4R A;  5DAE A;  1CT2 I;  2NU0 I;  1OMU A;  1UVG A;  1X74 A;  2N71 A;  4MPI A;  1OMT A;  2JA1 A;  4B6D A;  2UVO A;  1K7U A;  1WGT A;  1SGN I;  1TOT A;  2LB7 A;  3SGQ I;  1PPF I;  1PTQ A;  3VDU A;  3UFF A;  3BJI A;  5FUV A;  9WGA A;  1IW4 A;  1DS2 I;  3VE5 A;  4HGU A;  2DIP A;  2SGQ I;  1MJB A;  2DKV A;  3GOX A;  1CT0 I;  1HJA I;  3FC3 A;  3TO9 A;  1KBE A;  2N52 A;  1U5K A;  2RC4 A;  2JZM A;  1OVO A;  1KMA A;  1RFH A;  3OXL A;  2QQE A;  3OXG A;  1WGC A;  1XBT A;  2UZ3 A;  2V1C A;  5E3P A;  5J8F A;  1IY5 A;  2QQ0 A;  3TOB A;  3E2I A;  1UHA A;  3QWP A;  2KMQ A;  2SGF I;  2QPO A;  5HI7 A;  1SGR I;  1K7V A;  3HH2 C;  4L9M A;  3OL0 A;  4E1R A;  1OYV I;  2YQP A;  1R79 A;  2X52 A;  2DB6 A;  2WCY A;  3UGI A;  1Y1B A;  2FNF X;  1Y8F A;  1Z2I A;  2CWH A;  3FSY A;  2E5R A;  2N17 A;  2ARP F;  2KMO A;  4WP4 A;  1V1H A;  1PCE A;  2SGP I;  1CSO I;  4GI3 C;  3SGB I;  5CCL A;  1S20 A;  1UUC A;  1CHO I;  2KCX A;  2E73 A; 
#chains in the Genus database with same CATH homology
 1HPT A;  2ENN A;  3VDP A;  4UXI A;  2W0T A;  2ORV A;  1TUS A;  1FAQ A;  2V1C C;  2JXD A;  2QQC A;  1CT4 I;  1LR9 A;  2WVJ A;  2OD1 A;  1W3S A;  2J9R A;  4JCV E;  4A24 A;  5FUW A;  3SEK C;  2NU3 I;  2V53 A;  5FUX A;  5EX0 A;  1PTR A;  1BUS A;  3UEY A;  1R0R I;  1LR8 A;  3UGD A;  5CCM A;  2A20 A;  2LUY A;  4UXJ A;  1Y1C A;  3OVO A;  3B4V C;  1TBR R;  1SGE I;  2KMR A;  4UXH A;  1SGY I;  4SGB I;  1SGD I;  2GKV A;  2ROW A;  3TJQ A;  1TGS I;  1CE3 A;  3CXL A;  2K9H A;  1UVF A;  2CJS C;  2XRC A;  4OVO A;  1SGQ I;  2JW6 A;  5EX3 A;  1TBQ R;  2P6A C;  1TBO A;  1YTP A;  1HDL A;  1AN1 I;  1CGJ I;  1VDD A;  3UGL A;  1KBF A;  5FUY A;  2NU2 I;  2LEO A;  2SGD I;  1NUB A;  2F3C I;  2L7X A;  2GKR I;  2L8E A;  2ODD A;  4FKD A;  5HQ8 A;  1H0Z A;  2GKT I;  1LR7 A;  2GVI A;  2NU4 I;  3D00 A;  1SGP I;  3UEJ A;  2N1A B;  3RU0 A;  2VRW B;  2B8T A;  1CGI I;  1TUR A;  1BMO A;  1N13 A;  1X4S A;  1IY6 A;  1M8C A;  1TBN A;  2J87 A;  3QTL D;  1PJU A;  1XA6 A;  2YUU A;  2ELI A;  2BUS A;  2JYY A;  3OXF A;  5JHW C;  2ORW A;  3KY9 A;  2OVO A;  3MEK A;  2M5X A;  1V1I A;  1M8B A;  1FAR A;  4E1P A;  1TIH A;  1FYB A;  1Z7K B;  2ERW A;  2ENZ A;  3E59 A;  2NU1 I;  1DS3 I;  1XX6 A;  3PDN A;  1YU6 C;  2KMP A;  2SGE I;  1MT1 A;  2QQD A;  2B0U C;  1W4R A;  5DAE A;  1CT2 I;  2NU0 I;  1OMU A;  1UVG A;  1X74 A;  2N71 A;  1OMT A;  2JA1 A;  4B6D A;  1SGN I;  1TOT A;  3SGQ I;  1PPF I;  1PTQ A;  3VDU A;  3UFF A;  3BJI A;  5FUV A;  1IW4 A;  1DS2 I;  3VE5 A;  4HGU A;  2DIP A;  2SGQ I;  3GOX A;  1CT0 I;  1HJA I;  3FC3 A;  1KBE A;  2N52 A;  1U5K A;  2JZM A;  1OVO A;  1KMA A;  1RFH A;  3OXL A;  2QQE A;  3OXG A;  2V1C A;  1XBT A;  2UZ3 A;  1IY5 A;  2QQ0 A;  3E2I A;  3QWP A;  5HI7 A;  2KMQ A;  2SGF I;  2QPO A;  1SGR I;  3HH2 C;  4L9M A;  3OL0 A;  4E1R A;  1OYV I;  2YQP A;  1R79 A;  2DB6 A;  2WCY A;  3UGI A;  1Y1B A;  2FNF X;  1Y8F A;  2E5R A;  2N17 A;  2ARP F;  2KMO A;  1V1H A;  1PCE A;  2SGP I;  1CSO I;  4GI3 C;  3SGB I;  5CCL A;  1UUC A;  1CHO I;  2KCX A;  2E73 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...