1SGEI

Glu 18 variant of turkey ovomucoid inhibitor third domain complexed with streptomyces griseus proteinase b at ph 6.5
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
51
structure length
51
Chain Sequence
VDCSEYPKPACTEEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pHs
rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Meleagris gallopavo
molecule keywords Streptogrisin B
total genus 13
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 1999-03-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1sgeI00
2WCYA 1CHOI 3SGBI 2B0UC 1KMAA 1BUSA 1DS3I 1SGDI 1IW4A 2NU0I 1PJUA 2NU2I 1PPFI 1FYBA 2N71A 2SGDI 2KCXA 1SGNI 1UUCA 1DS2I 1N13A 1SGPI 4OVOA 1TIHA 1UVFA 1SGRI 1HJAI 2NU3I 1IY5A 2V53A 2N52A 2ERWA 1HDLA 1OMTA 2KMPA 4HGUA 1YU6C 2JYYA 4GI3C 1CGII 1CT0I 2ARPF 2JXDA 1M8BA 1SGYI 2JZMA 1UVGA 1OYVI 1LR7A 3SGQI 3SEKC 3B4VC 2NU4I 4SGBI 2GKVA 2F3CI 1IY6A 5JHWC 1CT4I 3TJQA 1R0RI 2QQCA 3OVOA 1CT2I 1Y1CA 2M5XA 2SGPI 2KMQA 1M8CA 1AN1I 3HH2C 1LR9A 2NU1I 1YTPA 1NUBA 1TBRR 2KMOA 1BMOA 2N17A 2SGFI 1CE3A 1TUSA 2BUSA 1SGQI 2GKTI 2SGEI 1H0ZA 1OMUA 1TURA 2P6AC 2LEOA 1SGEI 2SGQI 1Z7KB 1Y1BA 1MT1A 2QQDA 2KMRA 1HPTA 2OVOA 2GKRI 1OVOA 1CGJI 2XRCA 1TGSI 1LR8A 1CSOI 1PCEA 1TBQR 3QTLD 5DAEA
chains in the Genus database with same CATH superfamily
2WCYA 1CHOI 2K9HA 3SGBI 2B0UC 1K7UA 2UVOA 1KMAA 1BUSA 2VRWB 1ULNA 1DS3I 1SGDI 3UEYA 1IW4A 2NU0I 1PJUA 3UEJA 4E1PA 2B8TA 1PTRA 2QQEA 2NU2I 2X3TA 2X52A 4L9MA 1PPFI 2WGCA 2N71A 2ENNA 2OD1A 2SGDI 2KCXA 3UGLA 1FYBA 2W0TA 2ORVA 1FARA 4UXJA 1SGNI 1KBFA 1UUCA 5E3PA 1Y8FA 1NXUA 1U5KA 1DS2I 1N13A 2JA1A 5E3QA 2J87A 1WTJA 5J8FA 2L8EA 5J8CA 3FSYA 1SGPI 4OVOA 1TIHA 1UVFA 2WVJA 4FKDA 3BJIA 3FSXA 3R5DA 1TOTA 3R5AA 4JCVE 4UXIA 1SGRI 1X4SA 1RFHA 1WGCA 2ENZA 1HJAI 2OU2A 2NU3I 3OXLA 1IY5A 2YUUA 2V53A 2N52A 1Z2IA 1MJ9A 3GOXA 4E1RA 3VE5A 2ERWA 3QAHA 1HDLA 2A20A 4DNCA 1OMTA 1MJAA 2KMPA 2L7XA 2LB7A 4HGUA 3UOEA 2DB6A 1WGTA 1YU6C 2JYYA 1V1IA 2CJSC 2GVIA 4GI3C 1CGII 3VDUA 3E59A 2PQ8A 1CT0I 1X74A 2ARPF 3MEKA 2JXDA 4UXHA 1FY7A 1M8BA 1SGYI 2JZMA 1XX6A 2RIJA 3E2IA 3OXGA 3TOBA 1W4RA 2JW6A 1UVGA 1ULKA 2CWFA 3R5CA 3FC3A 2QQ0A 1P9ZA 1OYVI 1LR7A 2ELIA 3SGQI 3SEKC 3B4VC 2NU4I 4SGBI 4WP4A 2FNFX 2YQPA 3TO6A 4B6DA 1PTQA 3QWPA 2GKVA 2ROWA 2F3CI 1IY6A 7WGAA 2J9RA 3TO7A 5JHWC 5FUYA 1FAQA 1CT4I 1W3SA 2LUYA 3TJQA 1R0RI 2QQCA 5CCLA 3PDNA 3OVOA 3CXLA 1ULMA 1CT2I 1Y1CA 2M5XA 2SGPI 5FUXA 2KMQA 5FUWA 3RU0A 1M8CA 1AN1I 1TBOA 3D00A 2UZ3A 1LR9A 2NU1I 2DKVA 3HH2C 1KBEA 2CWGA 1YTPA 1NUBA 1TBRR 1V1HA 2V1CC 3TO9A 2E5RA 1WKXA 5EX0A 1R79A 5EX3A 2KMOA 1BMOA 2N17A 3OXFA 4MPIA 5CCMA 1XBTA 2SGFI 2Y0MA 3OL0A 1TBNA 5E3RA 3TOAA 2E73A 2GIVA 2ORWA 1CE3A 1TUSA 1HEVA 2DIPA 2BUSA 1SGQI 2GKTI 2RC4A 2SGEI 3UGDA 1OMUA 1TURA 1H0ZA 1VDDA 2P6AC 1K7VA 2LEOA 1SGEI 2QPOA 2SGQI 1Z7KB 3VDPA 2OZUA 2CWHA 1K7TA 1MJBA 1Y1BA 1MT1A 1UHAA 5FUVA 5HQ8A 2QQDA 2KMRA 4AMLA 3UFFA 1HPTA 1Q9BA 2OVOA 2GKRI 5HI7A 1OVOA 1XA6A 1CGJI 3R5BA 4A24A 2XRCA 1TGSI 2ODDA 1LR8A 3UGIA 3KY9A 1P9GA 1CSOI 1PCEA 1S20A 9WGAA 1TBQR 2V1CA 2N1AB 3QTLD 5DAEA
chains in the Genus database with same CATH topology
2WCYA 1CHOI 2K9HA 3SGBI 2B0UC 1KMAA 1BUSA 2VRWB 1DS3I 1SGDI 3UEYA 1IW4A 2NU0I 1PJUA 3UEJA 4E1PA 2B8TA 1PTRA 2QQEA 2NU2I 4L9MA 1PPFI 1FYBA 2N71A 2ENNA 2OD1A 2SGDI 2KCXA 3UGLA 2W0TA 2ORVA 1FARA 4UXJA 1SGNI 1KBFA 1UUCA 1Y8FA 1U5KA 1DS2I 1N13A 2JA1A 2J87A 2L8EA 1SGPI 4OVOA 1TIHA 1UVFA 2WVJA 4FKDA 3BJIA 4UXIA 1TOTA 4JCVE 1SGRI 1X4SA 1RFHA 2ENZA 1HJAI 2NU3I 3OXLA 1IY5A 2YUUA 2V53A 2N52A 3GOXA 4E1RA 3VE5A 2ERWA 1HDLA 2A20A 1OMTA 2KMPA 2L7XA 4HGUA 2DB6A 1YU6C 2JYYA 1V1IA 2CJSC 2GVIA 4GI3C 1CGII 3VDUA 3E59A 1CT0I 1X74A 2ARPF 3MEKA 2JXDA 4UXHA 1M8BA 1SGYI 2JZMA 1XX6A 3E2IA 3OXGA 1W4RA 2JW6A 1UVGA 3FC3A 2QQ0A 1OYVI 1LR7A 2ELIA 3SGQI 3SEKC 3B4VC 2NU4I 4SGBI 2FNFX 2YQPA 4B6DA 1PTQA 3QWPA 2GKVA 2ROWA 2F3CI 1IY6A 2J9RA 5JHWC 5FUYA 1FAQA 1CT4I 1W3SA 2LUYA 3TJQA 1R0RI 2QQCA 5CCLA 3PDNA 3OVOA 3CXLA 1CT2I 1Y1CA 2M5XA 2SGPI 5FUXA 2KMQA 5FUWA 3RU0A 1M8CA 1AN1I 1TBOA 3D00A 2UZ3A 1LR9A 2NU1I 3HH2C 1KBEA 1YTPA 1NUBA 1TBRR 1V1HA 2V1CC 2E5RA 5EX0A 1R79A 5EX3A 2KMOA 1BMOA 2N17A 3OXFA 5CCMA 1XBTA 2SGFI 3OL0A 1TBNA 2E73A 2ORWA 1CE3A 1TUSA 2DIPA 2BUSA 1SGQI 2GKTI 2SGEI 3UGDA 1H0ZA 1OMUA 1TURA 1VDDA 2P6AC 2QPOA 2LEOA 1SGEI 2SGQI 1Z7KB 3VDPA 1Y1BA 1MT1A 5FUVA 5HQ8A 2QQDA 2KMRA 3UFFA 1HPTA 2OVOA 2GKRI 5HI7A 1OVOA 1XA6A 1CGJI 4A24A 2XRCA 1TGSI 2ODDA 1LR8A 3UGIA 3KY9A 1CSOI 1PCEA 1TBQR 2V1CA 2N1AB 3QTLD 5DAEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WCY A;  1CHO I;  3SGB I;  2B0U C;  1KMA A;  1BUS A;  1DS3 I;  1SGD I;  1IW4 A;  2NU0 I;  1PJU A;  2NU2 I;  1PPF I;  1FYB A;  2N71 A;  2SGD I;  2KCX A;  1SGN I;  1UUC A;  1DS2 I;  1N13 A;  1SGP I;  4OVO A;  1TIH A;  1UVF A;  1SGR I;  1HJA I;  2NU3 I;  1IY5 A;  2V53 A;  2N52 A;  2ERW A;  1HDL A;  1OMT A;  2KMP A;  4HGU A;  1YU6 C;  2JYY A;  4GI3 C;  1CGI I;  1CT0 I;  2ARP F;  2JXD A;  1M8B A;  1SGY I;  2JZM A;  1UVG A;  1OYV I;  1LR7 A;  3SGQ I;  3SEK C;  3B4V C;  2NU4 I;  4SGB I;  2GKV A;  2F3C I;  1IY6 A;  5JHW C;  1CT4 I;  3TJQ A;  1R0R I;  2QQC A;  3OVO A;  1CT2 I;  1Y1C A;  2M5X A;  2SGP I;  2KMQ A;  1M8C A;  1AN1 I;  3HH2 C;  1LR9 A;  2NU1 I;  1YTP A;  1NUB A;  1TBR R;  2KMO A;  1BMO A;  2N17 A;  2SGF I;  1CE3 A;  1TUS A;  2BUS A;  1SGQ I;  2GKT I;  2SGE I;  1H0Z A;  1OMU A;  1TUR A;  2P6A C;  2LEO A;  1SGE I;  2SGQ I;  1Z7K B;  1Y1B A;  1MT1 A;  2QQD A;  2KMR A;  1HPT A;  2OVO A;  2GKR I;  1OVO A;  1CGJ I;  2XRC A;  1TGS I;  1LR8 A;  1CSO I;  1PCE A;  1TBQ R;  3QTL D;  5DAE A; 
#chains in the Genus database with same CATH topology
 2WCY A;  1CHO I;  2K9H A;  3SGB I;  2B0U C;  1K7U A;  2UVO A;  1KMA A;  1BUS A;  2VRW B;  1ULN A;  1DS3 I;  1SGD I;  3UEY A;  1IW4 A;  2NU0 I;  1PJU A;  3UEJ A;  4E1P A;  2B8T A;  1PTR A;  2QQE A;  2NU2 I;  2X3T A;  2X52 A;  4L9M A;  1PPF I;  2WGC A;  2N71 A;  2ENN A;  2OD1 A;  2SGD I;  2KCX A;  3UGL A;  1FYB A;  2W0T A;  2ORV A;  1FAR A;  4UXJ A;  1SGN I;  1KBF A;  1UUC A;  5E3P A;  1Y8F A;  1NXU A;  1U5K A;  1DS2 I;  1N13 A;  2JA1 A;  5E3Q A;  2J87 A;  1WTJ A;  5J8F A;  2L8E A;  5J8C A;  3FSY A;  1SGP I;  4OVO A;  1TIH A;  1UVF A;  2WVJ A;  4FKD A;  3BJI A;  3FSX A;  3R5D A;  1TOT A;  3R5A A;  4JCV E;  4UXI A;  1SGR I;  1X4S A;  1RFH A;  1WGC A;  2ENZ A;  1HJA I;  2OU2 A;  2NU3 I;  3OXL A;  1IY5 A;  2YUU A;  2V53 A;  2N52 A;  1Z2I A;  1MJ9 A;  3GOX A;  4E1R A;  3VE5 A;  2ERW A;  3QAH A;  1HDL A;  2A20 A;  4DNC A;  1OMT A;  1MJA A;  2KMP A;  2L7X A;  2LB7 A;  4HGU A;  3UOE A;  2DB6 A;  1WGT A;  1YU6 C;  2JYY A;  1V1I A;  2CJS C;  2GVI A;  4GI3 C;  1CGI I;  3VDU A;  3E59 A;  2PQ8 A;  1CT0 I;  1X74 A;  2ARP F;  3MEK A;  2JXD A;  4UXH A;  1FY7 A;  1M8B A;  1SGY I;  2JZM A;  1XX6 A;  2RIJ A;  3E2I A;  3OXG A;  3TOB A;  1W4R A;  2JW6 A;  1UVG A;  1ULK A;  2CWF A;  3R5C A;  3FC3 A;  2QQ0 A;  1P9Z A;  1OYV I;  1LR7 A;  2ELI A;  3SGQ I;  3SEK C;  3B4V C;  2NU4 I;  4SGB I;  4WP4 A;  2FNF X;  2YQP A;  3TO6 A;  4B6D A;  1PTQ A;  3QWP A;  2GKV A;  2ROW A;  2F3C I;  1IY6 A;  7WGA A;  2J9R A;  3TO7 A;  5JHW C;  5FUY A;  1FAQ A;  1CT4 I;  1W3S A;  2LUY A;  3TJQ A;  1R0R I;  2QQC A;  5CCL A;  3PDN A;  3OVO A;  3CXL A;  1ULM A;  1CT2 I;  1Y1C A;  2M5X A;  2SGP I;  5FUX A;  2KMQ A;  5FUW A;  3RU0 A;  1M8C A;  1AN1 I;  1TBO A;  3D00 A;  2UZ3 A;  1LR9 A;  2NU1 I;  2DKV A;  3HH2 C;  1KBE A;  2CWG A;  1YTP A;  1NUB A;  1TBR R;  1V1H A;  2V1C C;  3TO9 A;  2E5R A;  1WKX A;  5EX0 A;  1R79 A;  5EX3 A;  2KMO A;  1BMO A;  2N17 A;  3OXF A;  4MPI A;  5CCM A;  1XBT A;  2SGF I;  2Y0M A;  3OL0 A;  1TBN A;  5E3R A;  3TOA A;  2E73 A;  2GIV A;  2ORW A;  1CE3 A;  1TUS A;  1HEV A;  2DIP A;  2BUS A;  1SGQ I;  2GKT I;  2RC4 A;  2SGE I;  3UGD A;  1OMU A;  1TUR A;  1H0Z A;  1VDD A;  2P6A C;  1K7V A;  2LEO A;  1SGE I;  2QPO A;  2SGQ I;  1Z7K B;  3VDP A;  2OZU A;  2CWH A;  1K7T A;  1MJB A;  1Y1B A;  1MT1 A;  1UHA A;  5FUV A;  5HQ8 A;  2QQD A;  2KMR A;  4AML A;  3UFF A;  1HPT A;  1Q9B A;  2OVO A;  2GKR I;  5HI7 A;  1OVO A;  1XA6 A;  1CGJ I;  3R5B A;  4A24 A;  2XRC A;  1TGS I;  2ODD A;  1LR8 A;  3UGI A;  3KY9 A;  1P9G A;  1CSO I;  1PCE A;  1S20 A;  9WGA A;  1TBQ R;  2V1C A;  2N1A B;  3QTL D;  5DAE A; 
#chains in the Genus database with same CATH homology
 2WCY A;  1CHO I;  2K9H A;  3SGB I;  2B0U C;  1KMA A;  1BUS A;  2VRW B;  1DS3 I;  1SGD I;  3UEY A;  1IW4 A;  2NU0 I;  1PJU A;  3UEJ A;  4E1P A;  2B8T A;  1PTR A;  2QQE A;  2NU2 I;  4L9M A;  1PPF I;  1FYB A;  2N71 A;  2ENN A;  2OD1 A;  2SGD I;  2KCX A;  3UGL A;  2W0T A;  2ORV A;  1FAR A;  4UXJ A;  1SGN I;  1KBF A;  1UUC A;  1Y8F A;  1U5K A;  1DS2 I;  1N13 A;  2JA1 A;  2J87 A;  2L8E A;  1SGP I;  4OVO A;  1TIH A;  1UVF A;  2WVJ A;  4FKD A;  3BJI A;  4UXI A;  1TOT A;  4JCV E;  1SGR I;  1X4S A;  1RFH A;  2ENZ A;  1HJA I;  2NU3 I;  3OXL A;  1IY5 A;  2YUU A;  2V53 A;  2N52 A;  3GOX A;  4E1R A;  3VE5 A;  2ERW A;  1HDL A;  2A20 A;  1OMT A;  2KMP A;  2L7X A;  4HGU A;  2DB6 A;  1YU6 C;  2JYY A;  1V1I A;  2CJS C;  2GVI A;  4GI3 C;  1CGI I;  3VDU A;  3E59 A;  1CT0 I;  1X74 A;  2ARP F;  3MEK A;  2JXD A;  4UXH A;  1M8B A;  1SGY I;  2JZM A;  1XX6 A;  3E2I A;  3OXG A;  1W4R A;  2JW6 A;  1UVG A;  3FC3 A;  2QQ0 A;  1OYV I;  1LR7 A;  2ELI A;  3SGQ I;  3SEK C;  3B4V C;  2NU4 I;  4SGB I;  2FNF X;  2YQP A;  4B6D A;  1PTQ A;  3QWP A;  2GKV A;  2ROW A;  2F3C I;  1IY6 A;  2J9R A;  5JHW C;  5FUY A;  1FAQ A;  1CT4 I;  1W3S A;  2LUY A;  3TJQ A;  1R0R I;  2QQC A;  5CCL A;  3PDN A;  3OVO A;  3CXL A;  1CT2 I;  1Y1C A;  2M5X A;  2SGP I;  5FUX A;  2KMQ A;  5FUW A;  3RU0 A;  1M8C A;  1AN1 I;  1TBO A;  3D00 A;  2UZ3 A;  1LR9 A;  2NU1 I;  3HH2 C;  1KBE A;  1YTP A;  1NUB A;  1TBR R;  1V1H A;  2V1C C;  2E5R A;  5EX0 A;  1R79 A;  5EX3 A;  2KMO A;  1BMO A;  2N17 A;  3OXF A;  5CCM A;  1XBT A;  2SGF I;  3OL0 A;  1TBN A;  2E73 A;  2ORW A;  1CE3 A;  1TUS A;  2DIP A;  2BUS A;  1SGQ I;  2GKT I;  2SGE I;  3UGD A;  1H0Z A;  1OMU A;  1TUR A;  1VDD A;  2P6A C;  2QPO A;  2LEO A;  1SGE I;  2SGQ I;  1Z7K B;  3VDP A;  1Y1B A;  1MT1 A;  5FUV A;  5HQ8 A;  2QQD A;  2KMR A;  3UFF A;  1HPT A;  2OVO A;  2GKR I;  5HI7 A;  1OVO A;  1XA6 A;  1CGJ I;  4A24 A;  2XRC A;  1TGS I;  2ODD A;  1LR8 A;  3UGI A;  3KY9 A;  1CSO I;  1PCE A;  1TBQ R;  2V1C A;  2N1A B;  3QTL D;  5DAE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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