1SGRI

Leu 18 variant of turkey ovomucoid inhibitor third domain complexed with streptomyces griseus proteinase b
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
51
structure length
51
Chain Sequence
VDCSEYPKPACTLEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Complex (serine protease/inhibitor)
source organism Streptomyces griseus
publication title Water molecules participate in proteinase-inhibitor interactions: crystal structures of Leu18, Ala18, and Gly18 variants of turkey ovomucoid inhibitor third domain complexed with Streptomyces griseus proteinase B.
pubmed rcsb
molecule keywords STREPTOMYCES GRISEUS PROTEINASE B
total genus 13
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 1995-05-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1sgrI00
5DAEA 1CGJI 1TUSA 1YU6C 1N13A 1M8CA 2NU4I 1BUSA 2XRCA 1KMAA 1SGNI 1CHOI 2KMRA 1UVFA 2JYYA 1YTPA 1OMUA 1TBQR 1AN1I 3SEKC 1SGRI 1HJAI 2ERWA 4OVOA 4GI3C 1HPTA 1Y1BA 2ARPF 2V53A 1SGQI 1PCEA 2N17A 1H0ZA 2P6AC 3HH2C 3OVOA 1FYBA 2NU3I 1PJUA 2M5XA 2BUSA 2WCYA 2SGQI 1TBRR 1M8BA 2NU0I 1DS2I 2GKVA 3B4VC 1LR9A 2JZMA 2KMQA 1TGSI 3SGQI 1CGII 1R0RI 1IW4A 2LEOA 1IY6A 1NUBA 1CT4I 2JXDA 1LR8A 2QQCA 1TURA 2NU2I 1CT0I 1UUCA 5JHWC 1IY5A 3SGBI 2GKRI 1SGDI 1Y1CA 1SGYI 2KMOA 1TIHA 2KCXA 3TJQA 1Z7KB 1OVOA 1LR7A 2GKTI 1CE3A 3QTLD 1DS3I 2SGEI 2F3CI 2KMPA 1BMOA 2N71A 1OMTA 1SGPI 1CT2I 2N52A 2SGDI 2B0UC 2SGPI 1SGEI 4HGUA 4SGBI 1PPFI 1HDLA 2QQDA 2NU1I 2OVOA 1CSOI 1UVGA 2SGFI 1MT1A 1OYVI
chains in the Genus database with same CATH superfamily
5FUYA 5DAEA 5HQ8A 5J8FA 3TOAA 3TO9A 3KY9A 2L7XA 1CGJI 1TUSA 1YU6C 1WTJA 1N13A 1M8CA 2NU4I 3TO6A 1WKXA 3FSYA 1BUSA 2X3TA 2XRCA 1KMAA 1SGNI 1CHOI 2KMRA 1UVFA 2JYYA 1YTPA 1OMUA 1UHAA 1WGCA 1TBQR 1AN1I 2E73A 2JA1A 2K9HA 3R5CA 4MPIA 3SEKC 1SGRI 1HJAI 2ERWA 3OXFA 4OVOA 3UOEA 4GI3C 1HPTA 1MJAA 9WGAA 1VDDA 1Y1BA 2ARPF 1HEVA 2V53A 1SGQI 1PCEA 2N17A 2V1CC 3OXLA 1H0ZA 2P6AC 3HH2C 4UXJA 5CCLA 2V1CA 2GVIA 3OVOA 2Y0MA 1FYBA 3E2IA 2NU3I 3VDPA 1PJUA 2J87A 5EX3A 4JCVE 2M5XA 1X4SA 5EX0A 2BUSA 1PTRA 1PTQA 1ULMA 2ELIA 2WCYA 2SGQI 1W3SA 5E3PA 5FUVA 1TBRR 1XX6A 1XA6A 2OZUA 1MJBA 4E1RA 5CCMA 1M8BA 2NU0I 2QQ0A 1P9ZA 1DS2I 2GKVA 3UEYA 3B4VC 1FY7A 1FARA 1WGTA 2ODDA 3GOXA 1LR9A 2JZMA 2DKVA 2KMQA 1R79A 2YQPA 1TGSI 2DIPA 1CGII 3SGQI 4DNCA 3CXLA 1R0RI 1IW4A 1NXUA 2LEOA 3R5AA 1IY6A 1NUBA 2GIVA 1Q9BA 3D00A 3BJIA 3UEJA 2B8TA 3UFFA 1CT4I 1U5KA 5J8CA 2JXDA 2WVJA 2VRWB 2CJSC 1LR8A 2LUYA 2QQCA 1X74A 1TOTA 1ULKA 2FNFX 5FUXA 2JW6A 1TURA 2NU2I 1Y8FA 2DB6A 3PDNA 1CT0I 1S20A 1UUCA 5JHWC 1IY5A 2RIJA 3SGBI 1K7TA 2GKRI 1SGDI 1RFHA 1Y1CA 1Z2IA 1SGYI 2KMOA 2UZ3A 3QAHA 2ROWA 5FUWA 4E1PA 2W0TA 2LB7A 3RU0A 2PQ8A 4FKDA 1KBFA 1TIHA 2QQEA 2KCXA 3TJQA 1Z7KB 2E5RA 3TO7A 3UGDA 1P9GA 1V1HA 2A20A 3UGIA 1V1IA 1OVOA 1TBOA 1KBEA 2J9RA 3R5BA 1LR7A 3VDUA 1K7VA 4AMLA 7WGAA 2ORVA 2UVOA 1MJ9A 2GKTI 2CWGA 2YUUA 1CE3A 2CWFA 3FC3A 2X52A 3QTLD 1DS3I 2ENNA 2ENZA 2SGEI 3VE5A 2RC4A 4A24A 2F3CI 2KMPA 1W4RA 1BMOA 2L8EA 2N71A 1XBTA 5E3QA 3FSXA 1OMTA 1SGPI 3OXGA 4UXHA 3TOBA 1CT2I 2OU2A 2N52A 3QWPA 2SGDI 2B0UC 4L9MA 1K7UA 1SGEI 2SGPI 3OL0A 4HGUA 3R5DA 4SGBI 1PPFI 2CWHA 3MEKA 1TBNA 5HI7A 3UGLA 2ORWA 5E3RA 4UXIA 4B6DA 1HDLA 2QPOA 3E59A 2QQDA 4WP4A 2NU1I 2OD1A 2OVOA 1CSOI 1UVGA 1ULNA 2SGFI 2WGCA 1MT1A 1FAQA 2N1AB 1OYVI
chains in the Genus database with same CATH topology
5FUYA 5DAEA 5HQ8A 3KY9A 2L7XA 1CGJI 1TUSA 1YU6C 1N13A 1M8CA 2NU4I 1BUSA 2XRCA 1KMAA 1SGNI 1CHOI 2KMRA 1UVFA 2JYYA 1YTPA 1OMUA 2K9HA 1TBQR 1AN1I 2E73A 2JA1A 3SEKC 1SGRI 1HJAI 2ERWA 3OXFA 4OVOA 4GI3C 1HPTA 1VDDA 1Y1BA 2ARPF 2V53A 1SGQI 1PCEA 2N17A 2V1CC 3OXLA 1H0ZA 2P6AC 3HH2C 4UXJA 5CCLA 2V1CA 2GVIA 3OVOA 1FYBA 3E2IA 2NU3I 3VDPA 1PJUA 2J87A 5EX3A 4JCVE 2M5XA 1X4SA 5EX0A 2BUSA 1PTRA 1PTQA 2WCYA 2ELIA 2SGQI 1W3SA 5FUVA 1TBRR 1XX6A 1XA6A 4E1RA 5CCMA 1M8BA 2NU0I 2QQ0A 1DS2I 2GKVA 3UEYA 3B4VC 1FARA 2ODDA 3GOXA 1LR9A 2JZMA 2KMQA 1R79A 2YQPA 1TGSI 2DIPA 1CGII 3SGQI 3CXLA 1R0RI 1IW4A 2LEOA 1IY6A 1NUBA 3D00A 3BJIA 3UEJA 2B8TA 3UFFA 1CT4I 1U5KA 2JXDA 2WVJA 2VRWB 2CJSC 1LR8A 2LUYA 2QQCA 1X74A 1TOTA 2FNFX 5FUXA 2JW6A 1TURA 2NU2I 1Y8FA 2DB6A 3PDNA 1CT0I 1UUCA 5JHWC 1IY5A 3SGBI 2GKRI 1SGDI 1RFHA 1Y1CA 1SGYI 2KMOA 2UZ3A 2ROWA 5FUWA 4E1PA 2W0TA 3RU0A 4FKDA 1KBFA 1TIHA 2QQEA 2KCXA 3TJQA 1Z7KB 2E5RA 3UGDA 1V1HA 2A20A 3UGIA 1V1IA 1OVOA 1TBOA 1KBEA 2J9RA 1LR7A 3VDUA 2ORVA 2GKTI 2YUUA 1CE3A 3FC3A 3QTLD 1DS3I 2ENNA 2ENZA 2SGEI 3VE5A 4A24A 2F3CI 2KMPA 1W4RA 1BMOA 2L8EA 2N71A 1XBTA 1OMTA 1SGPI 3OXGA 4UXHA 1CT2I 3QWPA 2N52A 2SGDI 2B0UC 4L9MA 2SGPI 1SGEI 3OL0A 4HGUA 4SGBI 1PPFI 4B6DA 3MEKA 1TBNA 5HI7A 3UGLA 2ORWA 1HDLA 4UXIA 2QPOA 3E59A 2QQDA 2NU1I 2OD1A 2OVOA 1CSOI 1UVGA 2SGFI 1MT1A 1FAQA 2N1AB 1OYVI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DAE A;  1CGJ I;  1TUS A;  1YU6 C;  1N13 A;  1M8C A;  2NU4 I;  1BUS A;  2XRC A;  1KMA A;  1SGN I;  1CHO I;  2KMR A;  1UVF A;  2JYY A;  1YTP A;  1OMU A;  1TBQ R;  1AN1 I;  3SEK C;  1SGR I;  1HJA I;  2ERW A;  4OVO A;  4GI3 C;  1HPT A;  1Y1B A;  2ARP F;  2V53 A;  1SGQ I;  1PCE A;  2N17 A;  1H0Z A;  2P6A C;  3HH2 C;  3OVO A;  1FYB A;  2NU3 I;  1PJU A;  2M5X A;  2BUS A;  2WCY A;  2SGQ I;  1TBR R;  1M8B A;  2NU0 I;  1DS2 I;  2GKV A;  3B4V C;  1LR9 A;  2JZM A;  2KMQ A;  1TGS I;  3SGQ I;  1CGI I;  1R0R I;  1IW4 A;  2LEO A;  1IY6 A;  1NUB A;  1CT4 I;  2JXD A;  1LR8 A;  2QQC A;  1TUR A;  2NU2 I;  1CT0 I;  1UUC A;  5JHW C;  1IY5 A;  3SGB I;  2GKR I;  1SGD I;  1Y1C A;  1SGY I;  2KMO A;  1TIH A;  2KCX A;  3TJQ A;  1Z7K B;  1OVO A;  1LR7 A;  2GKT I;  1CE3 A;  3QTL D;  1DS3 I;  2SGE I;  2F3C I;  2KMP A;  1BMO A;  2N71 A;  1OMT A;  1SGP I;  1CT2 I;  2N52 A;  2SGD I;  2B0U C;  2SGP I;  1SGE I;  4HGU A;  4SGB I;  1PPF I;  1HDL A;  2QQD A;  2NU1 I;  2OVO A;  1CSO I;  1UVG A;  2SGF I;  1MT1 A;  1OYV I; 
#chains in the Genus database with same CATH topology
 5FUY A;  5DAE A;  5HQ8 A;  5J8F A;  3TOA A;  3TO9 A;  3KY9 A;  2L7X A;  1CGJ I;  1TUS A;  1YU6 C;  1WTJ A;  1N13 A;  1M8C A;  2NU4 I;  3TO6 A;  1WKX A;  3FSY A;  1BUS A;  2X3T A;  2XRC A;  1KMA A;  1SGN I;  1CHO I;  2KMR A;  1UVF A;  2JYY A;  1YTP A;  1OMU A;  1UHA A;  1WGC A;  1TBQ R;  1AN1 I;  2E73 A;  2JA1 A;  2K9H A;  3R5C A;  4MPI A;  3SEK C;  1SGR I;  1HJA I;  2ERW A;  3OXF A;  4OVO A;  3UOE A;  4GI3 C;  1HPT A;  1MJA A;  9WGA A;  1VDD A;  1Y1B A;  2ARP F;  1HEV A;  2V53 A;  1SGQ I;  1PCE A;  2N17 A;  2V1C C;  3OXL A;  1H0Z A;  2P6A C;  3HH2 C;  4UXJ A;  5CCL A;  2V1C A;  2GVI A;  3OVO A;  2Y0M A;  1FYB A;  3E2I A;  2NU3 I;  3VDP A;  1PJU A;  2J87 A;  5EX3 A;  4JCV E;  2M5X A;  1X4S A;  5EX0 A;  2BUS A;  1PTR A;  1PTQ A;  1ULM A;  2ELI A;  2WCY A;  2SGQ I;  1W3S A;  5E3P A;  5FUV A;  1TBR R;  1XX6 A;  1XA6 A;  2OZU A;  1MJB A;  4E1R A;  5CCM A;  1M8B A;  2NU0 I;  2QQ0 A;  1P9Z A;  1DS2 I;  2GKV A;  3UEY A;  3B4V C;  1FY7 A;  1FAR A;  1WGT A;  2ODD A;  3GOX A;  1LR9 A;  2JZM A;  2DKV A;  2KMQ A;  1R79 A;  2YQP A;  1TGS I;  2DIP A;  1CGI I;  3SGQ I;  4DNC A;  3CXL A;  1R0R I;  1IW4 A;  1NXU A;  2LEO A;  3R5A A;  1IY6 A;  1NUB A;  2GIV A;  1Q9B A;  3D00 A;  3BJI A;  3UEJ A;  2B8T A;  3UFF A;  1CT4 I;  1U5K A;  5J8C A;  2JXD A;  2WVJ A;  2VRW B;  2CJS C;  1LR8 A;  2LUY A;  2QQC A;  1X74 A;  1TOT A;  1ULK A;  2FNF X;  5FUX A;  2JW6 A;  1TUR A;  2NU2 I;  1Y8F A;  2DB6 A;  3PDN A;  1CT0 I;  1S20 A;  1UUC A;  5JHW C;  1IY5 A;  2RIJ A;  3SGB I;  1K7T A;  2GKR I;  1SGD I;  1RFH A;  1Y1C A;  1Z2I A;  1SGY I;  2KMO A;  2UZ3 A;  3QAH A;  2ROW A;  5FUW A;  4E1P A;  2W0T A;  2LB7 A;  3RU0 A;  2PQ8 A;  4FKD A;  1KBF A;  1TIH A;  2QQE A;  2KCX A;  3TJQ A;  1Z7K B;  2E5R A;  3TO7 A;  3UGD A;  1P9G A;  1V1H A;  2A20 A;  3UGI A;  1V1I A;  1OVO A;  1TBO A;  1KBE A;  2J9R A;  3R5B A;  1LR7 A;  3VDU A;  1K7V A;  4AML A;  7WGA A;  2ORV A;  2UVO A;  1MJ9 A;  2GKT I;  2CWG A;  2YUU A;  1CE3 A;  2CWF A;  3FC3 A;  2X52 A;  3QTL D;  1DS3 I;  2ENN A;  2ENZ A;  2SGE I;  3VE5 A;  2RC4 A;  4A24 A;  2F3C I;  2KMP A;  1W4R A;  1BMO A;  2L8E A;  2N71 A;  1XBT A;  5E3Q A;  3FSX A;  1OMT A;  1SGP I;  3OXG A;  4UXH A;  3TOB A;  1CT2 I;  2OU2 A;  2N52 A;  3QWP A;  2SGD I;  2B0U C;  4L9M A;  1K7U A;  1SGE I;  2SGP I;  3OL0 A;  4HGU A;  3R5D A;  4SGB I;  1PPF I;  2CWH A;  3MEK A;  1TBN A;  5HI7 A;  3UGL A;  2ORW A;  5E3R A;  4UXI A;  4B6D A;  1HDL A;  2QPO A;  3E59 A;  2QQD A;  4WP4 A;  2NU1 I;  2OD1 A;  2OVO A;  1CSO I;  1UVG A;  1ULN A;  2SGF I;  2WGC A;  1MT1 A;  1FAQ A;  2N1A B;  1OYV I; 
#chains in the Genus database with same CATH homology
 5FUY A;  5DAE A;  5HQ8 A;  3KY9 A;  2L7X A;  1CGJ I;  1TUS A;  1YU6 C;  1N13 A;  1M8C A;  2NU4 I;  1BUS A;  2XRC A;  1KMA A;  1SGN I;  1CHO I;  2KMR A;  1UVF A;  2JYY A;  1YTP A;  1OMU A;  2K9H A;  1TBQ R;  1AN1 I;  2E73 A;  2JA1 A;  3SEK C;  1SGR I;  1HJA I;  2ERW A;  3OXF A;  4OVO A;  4GI3 C;  1HPT A;  1VDD A;  1Y1B A;  2ARP F;  2V53 A;  1SGQ I;  1PCE A;  2N17 A;  2V1C C;  3OXL A;  1H0Z A;  2P6A C;  3HH2 C;  4UXJ A;  5CCL A;  2V1C A;  2GVI A;  3OVO A;  1FYB A;  3E2I A;  2NU3 I;  3VDP A;  1PJU A;  2J87 A;  5EX3 A;  4JCV E;  2M5X A;  1X4S A;  5EX0 A;  2BUS A;  1PTR A;  1PTQ A;  2WCY A;  2ELI A;  2SGQ I;  1W3S A;  5FUV A;  1TBR R;  1XX6 A;  1XA6 A;  4E1R A;  5CCM A;  1M8B A;  2NU0 I;  2QQ0 A;  1DS2 I;  2GKV A;  3UEY A;  3B4V C;  1FAR A;  2ODD A;  3GOX A;  1LR9 A;  2JZM A;  2KMQ A;  1R79 A;  2YQP A;  1TGS I;  2DIP A;  1CGI I;  3SGQ I;  3CXL A;  1R0R I;  1IW4 A;  2LEO A;  1IY6 A;  1NUB A;  3D00 A;  3BJI A;  3UEJ A;  2B8T A;  3UFF A;  1CT4 I;  1U5K A;  2JXD A;  2WVJ A;  2VRW B;  2CJS C;  1LR8 A;  2LUY A;  2QQC A;  1X74 A;  1TOT A;  2FNF X;  5FUX A;  2JW6 A;  1TUR A;  2NU2 I;  1Y8F A;  2DB6 A;  3PDN A;  1CT0 I;  1UUC A;  5JHW C;  1IY5 A;  3SGB I;  2GKR I;  1SGD I;  1RFH A;  1Y1C A;  1SGY I;  2KMO A;  2UZ3 A;  2ROW A;  5FUW A;  4E1P A;  2W0T A;  3RU0 A;  4FKD A;  1KBF A;  1TIH A;  2QQE A;  2KCX A;  3TJQ A;  1Z7K B;  2E5R A;  3UGD A;  1V1H A;  2A20 A;  3UGI A;  1V1I A;  1OVO A;  1TBO A;  1KBE A;  2J9R A;  1LR7 A;  3VDU A;  2ORV A;  2GKT I;  2YUU A;  1CE3 A;  3FC3 A;  3QTL D;  1DS3 I;  2ENN A;  2ENZ A;  2SGE I;  3VE5 A;  4A24 A;  2F3C I;  2KMP A;  1W4R A;  1BMO A;  2L8E A;  2N71 A;  1XBT A;  1OMT A;  1SGP I;  3OXG A;  4UXH A;  1CT2 I;  3QWP A;  2N52 A;  2SGD I;  2B0U C;  4L9M A;  2SGP I;  1SGE I;  3OL0 A;  4HGU A;  4SGB I;  1PPF I;  4B6D A;  3MEK A;  1TBN A;  5HI7 A;  3UGL A;  2ORW A;  1HDL A;  4UXI A;  2QPO A;  3E59 A;  2QQD A;  2NU1 I;  2OD1 A;  2OVO A;  1CSO I;  1UVG A;  2SGF I;  1MT1 A;  1FAQ A;  2N1A B;  1OYV I; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...