1SGYI

Tyr 18 variant of turkey ovomucoid inhibitor third domain complexed with streptomyces griseus proteinase b at ph 6.5
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
51
structure length
51
Chain Sequence
VDCSEYPKPACTYEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
source organism Meleagris gallopavo
publication title Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's
rcsb
molecule keywords Streptogrisin B
total genus 12
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 1999-03-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1sgyI00
2KMQA 2KMRA 1M8BA 1LR8A 1FYBA 4GI3C 2SGDI 1SGYI 1TBRR 1HJAI 2NU4I 1M8CA 1SGQI 1BUSA 1DS3I 1LR7A 2SGFI 3OVOA 3SEKC 1TGSI 1TUSA 1HPTA 1Z7KB 1OMUA 1IY6A 1BMOA 1N13A 2M5XA 2GKRI 3SGQI 1SGRI 3TJQA 1SGNI 2KMPA 2ERWA 1CHOI 1CT4I 5JHWC 1NUBA 1R0RI 2JZMA 2N71A 2QQDA 1OYVI 1AN1I 1Y1BA 4HGUA 4SGBI 1CSOI 1MT1A 1HDLA 1PCEA 3SGBI 1SGDI 1TBQR 1OMTA 1OVOA 1LR9A 1SGEI 1Y1CA 2N52A 1TURA 2LEOA 2F3CI 2P6AC 2SGQI 1UVFA 2NU0I 1YU6C 1CT0I 5DAEA 3QTLD 2B0UC 1TIHA 1H0ZA 2SGEI 2GKTI 2GKVA 2WCYA 1SGPI 1IW4A 2KCXA 1PJUA 4OVOA 1CGJI 1DS2I 2XRCA 1IY5A 2BUSA 1CGII 2N17A 1CE3A 2JYYA 3HH2C 2KMOA 2NU3I 1YTPA 1UVGA 3B4VC 2QQCA 1KMAA 1PPFI 2SGPI 2NU2I 1UUCA 2OVOA 2JXDA 2NU1I 2V53A 1CT2I 2ARPF
chains in the Genus database with same CATH superfamily
2KMQA 2KMRA 1RFHA 1M8BA 1LR8A 2ARPF 2LB7A 1FYBA 1K7TA 4GI3C 1ULNA 2SGDI 1SGYI 1TBRR 2V1CA 2X3TA 2ODDA 1HJAI 2NU4I 3UGIA 1KBFA 1M8CA 2VRWB 1SGQI 2OZUA 1BUSA 1DS3I 3R5AA 1ULKA 2LUYA 2ELIA 1MJAA 1PTRA 3PDNA 1WGTA 2CWFA 1LR7A 2SGFI 3OVOA 3SEKC 1TGSI 2ORVA 2WVJA 2YQPA 3UEJA 4E1PA 1TUSA 1HPTA 5EX0A 1XX6A 1Z7KB 3BJIA 3VDUA 5CCLA 2ORWA 2YUUA 1K7VA 1OMUA 1IY6A 1BMOA 1N13A 1Z2IA 1FAQA 2M5XA 2GKRI 2W0TA 2ENNA 3SGQI 2CWHA 5FUWA 1TBNA 1W3SA 1WTJA 1SGRI 5EX3A 3TJQA 1SGNI 2L8EA 1TOTA 4DNCA 2KMPA 3QWPA 1P9GA 2N1AB 3QAHA 4UXJA 2ERWA 1CT4I 3FSYA 5JHWC 1NUBA 1R0RI 1MJ9A 2JZMA 5CCMA 3TO6A 1W4RA 2N71A 2QPOA 2UZ3A 2QQDA 5FUVA 7WGAA 1OYVI 1P9ZA 5E3PA 1AN1I 1Y1BA 4HGUA 4SGBI 3UFFA 5J8FA 4UXHA 1CSOI 1MT1A 5J8CA 1HDLA 2OD1A 1PCEA 4E1RA 1UHAA 4MPIA 5HQ8A 3R5DA 4L9MA 2RIJA 3R5CA 3SGBI 1SGDI 1TBQR 1OMTA 2ENZA 2JW6A 1OVOA 5E3RA 1LR9A 3R5BA 1SGEI 1Y1CA 2E5RA 1ULMA 1K7UA 2N52A 2PQ8A 2UVOA 1TURA 2LEOA 1XBTA 2J9RA 3RU0A 2F3CI 2P6AC 3TOBA 4A24A 2L7XA 2SGQI 1UVFA 2NU0I 3UEYA 2GIVA 1YU6C 2RC4A 3UGDA 2J87A 3MEKA 9WGAA 2FNFX 3GOXA 1WGCA 1X4SA 2QQ0A 2GVIA 5FUYA 1CT0I 3OXGA 1R79A 5E3QA 1FY7A 5DAEA 2OU2A 3QTLD 2B0UC 1TBOA 3D00A 1KBEA 1NXUA 1TIHA 2DKVA 4UXIA 1H0ZA 2SGEI 2JA1A 2GKTI 3TO7A 2GKVA 1X74A 2WGCA 2CJSC 1PTQA 2WCYA 1U5KA 3OL0A 3OXFA 2DIPA 4JCVE 1Q9BA 1SGPI 1IW4A 2KCXA 2V1CC 3UOEA 1PJUA 3E59A 3VE5A 2QQEA 3FC3A 4OVOA 3TO9A 1CGJI 1XA6A 1DS2I 2Y0MA 2XRCA 1IY5A 2BUSA 1CGII 2N17A 2A20A 1CE3A 1HEVA 2JYYA 3FSXA 1FARA 3CXLA 2DB6A 3HH2C 3KY9A 2KMOA 5HI7A 1VDDA 1WKXA 3E2IA 2CWGA 4B6DA 1MJBA 2NU3I 3VDPA 1S20A 1UVGA 1YTPA 1Y8FA 2B8TA 3B4VC 2ROWA 1V1HA 2QQCA 3UGLA 5FUXA 1KMAA 1PPFI 2SGPI 3OXLA 4FKDA 4WP4A 2NU2I 1UUCA 2OVOA 2JXDA 2E73A 2X52A 2NU1I 4AMLA 2V53A 3TOAA 2K9HA 1CT2I 1V1IA 1CHOI
chains in the Genus database with same CATH topology
2KMQA 2KMRA 1RFHA 1M8BA 1LR8A 1FYBA 4GI3C 2SGDI 1SGYI 1TBRR 2V1CA 2ODDA 1HJAI 2NU4I 3UGIA 1KBFA 1M8CA 2VRWB 1SGQI 1BUSA 1DS3I 2LUYA 2ELIA 1PTRA 3PDNA 1LR7A 2SGFI 3OVOA 3SEKC 1TGSI 2ORVA 2WVJA 2YQPA 3UEJA 4E1PA 1TUSA 1HPTA 5EX0A 1XX6A 1Z7KB 3BJIA 3VDUA 5CCLA 2ORWA 2YUUA 1OMUA 1IY6A 1BMOA 1N13A 1FAQA 2M5XA 2GKRI 2W0TA 2ENNA 3SGQI 5FUWA 1TBNA 1W3SA 1SGRI 5EX3A 3TJQA 1SGNI 2L8EA 1TOTA 2KMPA 3QWPA 2N1AB 4UXJA 1CHOI 2ERWA 1CT4I 5JHWC 1NUBA 1R0RI 2JZMA 5CCMA 1W4RA 2N71A 2QPOA 2UZ3A 2QQDA 5FUVA 1OYVI 1AN1I 1Y1BA 4HGUA 4SGBI 3UFFA 4UXHA 1CSOI 1MT1A 1HDLA 2OD1A 1PCEA 4E1RA 5HQ8A 4L9MA 3SGBI 1SGDI 1TBQR 1OMTA 2ENZA 2JW6A 1OVOA 1LR9A 1SGEI 1Y1CA 2E5RA 2N52A 3RU0A 1TURA 2LEOA 1XBTA 2J9RA 2F3CI 2P6AC 4A24A 2L7XA 2SGQI 1UVFA 2NU0I 3UEYA 1YU6C 3UGDA 2J87A 3MEKA 2FNFX 3GOXA 1X4SA 2QQ0A 2GVIA 1CT0I 3OXGA 1R79A 5DAEA 5FUYA 3QTLD 2B0UC 1TBOA 3D00A 1KBEA 1TIHA 4UXIA 1H0ZA 2SGEI 2JA1A 2GKTI 2GKVA 1X74A 2CJSC 1PTQA 2WCYA 1U5KA 3OL0A 3OXFA 2DIPA 4JCVE 1SGPI 1IW4A 2KCXA 2V1CC 1PJUA 3E59A 3VE5A 2QQEA 4OVOA 1CGJI 1XA6A 1DS2I 2XRCA 1IY5A 2BUSA 1CGII 2N17A 2A20A 1CE3A 2JYYA 1FARA 3CXLA 2DB6A 3HH2C 3KY9A 2KMOA 5HI7A 1VDDA 4B6DA 3E2IA 3FC3A 3VDPA 2NU3I 1YTPA 1UVGA 2B8TA 1Y8FA 3B4VC 2ROWA 1V1HA 2QQCA 3UGLA 5FUXA 1KMAA 1PPFI 2SGPI 3OXLA 4FKDA 2NU2I 1UUCA 2OVOA 2JXDA 2E73A 2NU1I 2V53A 2K9HA 1CT2I 1V1IA 2ARPF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KMQ A;  2KMR A;  1M8B A;  1LR8 A;  1FYB A;  4GI3 C;  2SGD I;  1SGY I;  1TBR R;  1HJA I;  2NU4 I;  1M8C A;  1SGQ I;  1BUS A;  1DS3 I;  1LR7 A;  2SGF I;  3OVO A;  3SEK C;  1TGS I;  1TUS A;  1HPT A;  1Z7K B;  1OMU A;  1IY6 A;  1BMO A;  1N13 A;  2M5X A;  2GKR I;  3SGQ I;  1SGR I;  3TJQ A;  1SGN I;  2KMP A;  2ERW A;  1CHO I;  1CT4 I;  5JHW C;  1NUB A;  1R0R I;  2JZM A;  2N71 A;  2QQD A;  1OYV I;  1AN1 I;  1Y1B A;  4HGU A;  4SGB I;  1CSO I;  1MT1 A;  1HDL A;  1PCE A;  3SGB I;  1SGD I;  1TBQ R;  1OMT A;  1OVO A;  1LR9 A;  1SGE I;  1Y1C A;  2N52 A;  1TUR A;  2LEO A;  2F3C I;  2P6A C;  2SGQ I;  1UVF A;  2NU0 I;  1YU6 C;  1CT0 I;  5DAE A;  3QTL D;  2B0U C;  1TIH A;  1H0Z A;  2SGE I;  2GKT I;  2GKV A;  2WCY A;  1SGP I;  1IW4 A;  2KCX A;  1PJU A;  4OVO A;  1CGJ I;  1DS2 I;  2XRC A;  1IY5 A;  2BUS A;  1CGI I;  2N17 A;  1CE3 A;  2JYY A;  3HH2 C;  2KMO A;  2NU3 I;  1YTP A;  1UVG A;  3B4V C;  2QQC A;  1KMA A;  1PPF I;  2SGP I;  2NU2 I;  1UUC A;  2OVO A;  2JXD A;  2NU1 I;  2V53 A;  1CT2 I;  2ARP F; 
#chains in the Genus database with same CATH topology
 2KMQ A;  2KMR A;  1RFH A;  1M8B A;  1LR8 A;  2ARP F;  2LB7 A;  1FYB A;  1K7T A;  4GI3 C;  1ULN A;  2SGD I;  1SGY I;  1TBR R;  2V1C A;  2X3T A;  2ODD A;  1HJA I;  2NU4 I;  3UGI A;  1KBF A;  1M8C A;  2VRW B;  1SGQ I;  2OZU A;  1BUS A;  1DS3 I;  3R5A A;  1ULK A;  2LUY A;  2ELI A;  1MJA A;  1PTR A;  3PDN A;  1WGT A;  2CWF A;  1LR7 A;  2SGF I;  3OVO A;  3SEK C;  1TGS I;  2ORV A;  2WVJ A;  2YQP A;  3UEJ A;  4E1P A;  1TUS A;  1HPT A;  5EX0 A;  1XX6 A;  1Z7K B;  3BJI A;  3VDU A;  5CCL A;  2ORW A;  2YUU A;  1K7V A;  1OMU A;  1IY6 A;  1BMO A;  1N13 A;  1Z2I A;  1FAQ A;  2M5X A;  2GKR I;  2W0T A;  2ENN A;  3SGQ I;  2CWH A;  5FUW A;  1TBN A;  1W3S A;  1WTJ A;  1SGR I;  5EX3 A;  3TJQ A;  1SGN I;  2L8E A;  1TOT A;  4DNC A;  2KMP A;  3QWP A;  1P9G A;  2N1A B;  3QAH A;  4UXJ A;  2ERW A;  1CT4 I;  3FSY A;  5JHW C;  1NUB A;  1R0R I;  1MJ9 A;  2JZM A;  5CCM A;  3TO6 A;  1W4R A;  2N71 A;  2QPO A;  2UZ3 A;  2QQD A;  5FUV A;  7WGA A;  1OYV I;  1P9Z A;  5E3P A;  1AN1 I;  1Y1B A;  4HGU A;  4SGB I;  3UFF A;  5J8F A;  4UXH A;  1CSO I;  1MT1 A;  5J8C A;  1HDL A;  2OD1 A;  1PCE A;  4E1R A;  1UHA A;  4MPI A;  5HQ8 A;  3R5D A;  4L9M A;  2RIJ A;  3R5C A;  3SGB I;  1SGD I;  1TBQ R;  1OMT A;  2ENZ A;  2JW6 A;  1OVO A;  5E3R A;  1LR9 A;  3R5B A;  1SGE I;  1Y1C A;  2E5R A;  1ULM A;  1K7U A;  2N52 A;  2PQ8 A;  2UVO A;  1TUR A;  2LEO A;  1XBT A;  2J9R A;  3RU0 A;  2F3C I;  2P6A C;  3TOB A;  4A24 A;  2L7X A;  2SGQ I;  1UVF A;  2NU0 I;  3UEY A;  2GIV A;  1YU6 C;  2RC4 A;  3UGD A;  2J87 A;  3MEK A;  9WGA A;  2FNF X;  3GOX A;  1WGC A;  1X4S A;  2QQ0 A;  2GVI A;  5FUY A;  1CT0 I;  3OXG A;  1R79 A;  5E3Q A;  1FY7 A;  5DAE A;  2OU2 A;  3QTL D;  2B0U C;  1TBO A;  3D00 A;  1KBE A;  1NXU A;  1TIH A;  2DKV A;  4UXI A;  1H0Z A;  2SGE I;  2JA1 A;  2GKT I;  3TO7 A;  2GKV A;  1X74 A;  2WGC A;  2CJS C;  1PTQ A;  2WCY A;  1U5K A;  3OL0 A;  3OXF A;  2DIP A;  4JCV E;  1Q9B A;  1SGP I;  1IW4 A;  2KCX A;  2V1C C;  3UOE A;  1PJU A;  3E59 A;  3VE5 A;  2QQE A;  3FC3 A;  4OVO A;  3TO9 A;  1CGJ I;  1XA6 A;  1DS2 I;  2Y0M A;  2XRC A;  1IY5 A;  2BUS A;  1CGI I;  2N17 A;  2A20 A;  1CE3 A;  1HEV A;  2JYY A;  3FSX A;  1FAR A;  3CXL A;  2DB6 A;  3HH2 C;  3KY9 A;  2KMO A;  5HI7 A;  1VDD A;  1WKX A;  3E2I A;  2CWG A;  4B6D A;  1MJB A;  2NU3 I;  3VDP A;  1S20 A;  1UVG A;  1YTP A;  1Y8F A;  2B8T A;  3B4V C;  2ROW A;  1V1H A;  2QQC A;  3UGL A;  5FUX A;  1KMA A;  1PPF I;  2SGP I;  3OXL A;  4FKD A;  4WP4 A;  2NU2 I;  1UUC A;  2OVO A;  2JXD A;  2E73 A;  2X52 A;  2NU1 I;  4AML A;  2V53 A;  3TOA A;  2K9H A;  1CT2 I;  1V1I A;  1CHO I; 
#chains in the Genus database with same CATH homology
 2KMQ A;  2KMR A;  1RFH A;  1M8B A;  1LR8 A;  1FYB A;  4GI3 C;  2SGD I;  1SGY I;  1TBR R;  2V1C A;  2ODD A;  1HJA I;  2NU4 I;  3UGI A;  1KBF A;  1M8C A;  2VRW B;  1SGQ I;  1BUS A;  1DS3 I;  2LUY A;  2ELI A;  1PTR A;  3PDN A;  1LR7 A;  2SGF I;  3OVO A;  3SEK C;  1TGS I;  2ORV A;  2WVJ A;  2YQP A;  3UEJ A;  4E1P A;  1TUS A;  1HPT A;  5EX0 A;  1XX6 A;  1Z7K B;  3BJI A;  3VDU A;  5CCL A;  2ORW A;  2YUU A;  1OMU A;  1IY6 A;  1BMO A;  1N13 A;  1FAQ A;  2M5X A;  2GKR I;  2W0T A;  2ENN A;  3SGQ I;  5FUW A;  1TBN A;  1W3S A;  1SGR I;  5EX3 A;  3TJQ A;  1SGN I;  2L8E A;  1TOT A;  2KMP A;  3QWP A;  2N1A B;  4UXJ A;  1CHO I;  2ERW A;  1CT4 I;  5JHW C;  1NUB A;  1R0R I;  2JZM A;  5CCM A;  1W4R A;  2N71 A;  2QPO A;  2UZ3 A;  2QQD A;  5FUV A;  1OYV I;  1AN1 I;  1Y1B A;  4HGU A;  4SGB I;  3UFF A;  4UXH A;  1CSO I;  1MT1 A;  1HDL A;  2OD1 A;  1PCE A;  4E1R A;  5HQ8 A;  4L9M A;  3SGB I;  1SGD I;  1TBQ R;  1OMT A;  2ENZ A;  2JW6 A;  1OVO A;  1LR9 A;  1SGE I;  1Y1C A;  2E5R A;  2N52 A;  3RU0 A;  1TUR A;  2LEO A;  1XBT A;  2J9R A;  2F3C I;  2P6A C;  4A24 A;  2L7X A;  2SGQ I;  1UVF A;  2NU0 I;  3UEY A;  1YU6 C;  3UGD A;  2J87 A;  3MEK A;  2FNF X;  3GOX A;  1X4S A;  2QQ0 A;  2GVI A;  1CT0 I;  3OXG A;  1R79 A;  5DAE A;  5FUY A;  3QTL D;  2B0U C;  1TBO A;  3D00 A;  1KBE A;  1TIH A;  4UXI A;  1H0Z A;  2SGE I;  2JA1 A;  2GKT I;  2GKV A;  1X74 A;  2CJS C;  1PTQ A;  2WCY A;  1U5K A;  3OL0 A;  3OXF A;  2DIP A;  4JCV E;  1SGP I;  1IW4 A;  2KCX A;  2V1C C;  1PJU A;  3E59 A;  3VE5 A;  2QQE A;  4OVO A;  1CGJ I;  1XA6 A;  1DS2 I;  2XRC A;  1IY5 A;  2BUS A;  1CGI I;  2N17 A;  2A20 A;  1CE3 A;  2JYY A;  1FAR A;  3CXL A;  2DB6 A;  3HH2 C;  3KY9 A;  2KMO A;  5HI7 A;  1VDD A;  4B6D A;  3E2I A;  3FC3 A;  3VDP A;  2NU3 I;  1YTP A;  1UVG A;  2B8T A;  1Y8F A;  3B4V C;  2ROW A;  1V1H A;  2QQC A;  3UGL A;  5FUX A;  1KMA A;  1PPF I;  2SGP I;  3OXL A;  4FKD A;  2NU2 I;  1UUC A;  2OVO A;  2JXD A;  2E73 A;  2NU1 I;  2V53 A;  2K9H A;  1CT2 I;  1V1I A;  2ARP F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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