1TGSI

Three-dimensional structure of the complex between pancreatic secretory inhibitor (kazal type) and trypsinogen at 1.8 angstroms resolution. structure solution, crystallographic refinement and preliminary structural interpretation
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
56
structure length
56
Chain Sequence
TSPQREATCTSEVSGCPKIYNPVCGTDGITYSNECVLCSENKKRQTPVLIQKSGPC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Three-dimensional structure of the complex between pancreatic secretory trypsin inhibitor (Kazal type) and trypsinogen at 1.8 A resolution. Structure solution, crystallographic refinement and preliminary structural interpretation.
pubmed doi rcsb
molecule tags Complex (proteinase/inhibitor)
source organism Bos taurus
molecule keywords TRYPSINOGEN
total genus 13
structure length 56
sequence length 56
ec nomenclature
pdb deposition date 1982-09-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1tgsI00
1TBQR 2KMPA 1BMOA 2NU3I 4GI3C 2SGDI 1OVOA 1CGJI 1SGDI 1CGII 1YTPA 1Y1CA 1SGEI 1OMTA 1TIHA 2GKTI 3HH2C 2SGPI 1Y1BA 3SGBI 1H0ZA 1N13A 1YU6C 2KMOA 1LR7A 1PPFI 1MT1A 1CT0I 1LR8A 3OVOA 1TURA 3QTLD 1HJAI 1SGYI 1IY5A 1SGQI 1R0RI 1TUSA 2QQCA 1IY6A 2XRCA 2LEOA 1DS3I 1SGRI 2F3CI 1UVGA 2JYYA 1UUCA 2QQDA 1M8CA 1M8BA 2JXDA 2N17A 2B0UC 3TJQA 4HGUA 1TBRR 4SGBI 1HDLA 2WCYA 1OYVI 2SGQI 2NU0I 1CHOI 2ARPF 1PJUA 1NUBA 1HPTA 2KMRA 2NU1I 2SGEI 2OVOA 3SEKC 1IW4A 5DAEA 1CT4I 1SGPI 1OMUA 2P6AC 1BUSA 3B4VC 2KMQA 1CSOI 1SGNI 3SGQI 1AN1I 1DS2I 5JHWC 1CT2I 2ERWA 2KCXA 1PCEA 2SGFI 2V53A 2N71A 1Z7KB 2N52A 2JZMA 2GKVA 2NU4I 1UVFA 1KMAA 1FYBA 2NU2I 1LR9A 2GKRI 1CE3A 4OVOA 1TGSI 2BUSA 2M5XA
chains in the Genus database with same CATH superfamily
3TO7A 1TBQR 2KMPA 1BMOA 1WKXA 2JW6A 2NU3I 4GI3C 2SGDI 1OVOA 3E2IA 3UFFA 1CGJI 1SGDI 1CGII 1S20A 1YTPA 5FUVA 3TOAA 1PTQA 1Y1CA 1SGEI 1XX6A 3QAHA 3QWPA 2YUUA 1OMTA 1TIHA 2GKTI 3HH2C 4E1PA 2W0TA 3UGIA 2SGPI 2OU2A 2QQEA 1K7VA 1Y1BA 2WVJA 2Y0MA 3FSYA 1K7UA 1N13A 1YU6C 2ENNA 2KMOA 2X3TA 4UXJA 2N1AB 1H0ZA 1WGCA 1LR7A 1PPFI 1CT0I 1LR8A 1KBFA 3CXLA 1TURA 3OVOA 2PQ8A 3UGDA 3QTLD 1NXUA 1W3SA 1TOTA 2QPOA 1HJAI 2RIJA 1SGYI 3UGLA 5E3PA 1IY5A 1SGQI 1R0RI 1TUSA 2QQCA 4UXHA 2XRCA 1IY6A 5EX3A 2GIVA 1P9GA 2L8EA 2LEOA 3TO9A 5J8FA 1DS3I 2L7XA 2CJSC 1TBOA 1SGRI 3OXLA 2F3CI 1UVGA 2JYYA 2K9HA 3R5DA 3VDPA 1Y8FA 2ENZA 1V1HA 5HQ8A 1UUCA 5E3QA 2QQDA 3PDNA 3TO6A 3VE5A 2E5RA 1M8CA 2CWHA 9WGAA 2UZ3A 2J87A 1M8BA 1WGTA 1VDDA 2JXDA 1UHAA 2QQ0A 2RC4A 4E1RA 1PTRA 2N17A 2X52A 2OD1A 2B0UC 5CCLA 3TJQA 1MJAA 2DB6A 2JA1A 2UVOA 2B8TA 1U5KA 4HGUA 3D00A 1TBRR 3OL0A 4JCVE 4SGBI 3VDUA 5FUYA 1HDLA 2WCYA 2A20A 1OYVI 2SGQI 2NU0I 3MEKA 2FNFX 5EX0A 1CHOI 3R5BA 2ARPF 1PJUA 1NUBA 3OXGA 4DNCA 2M5XA 1HPTA 1RFHA 2KMRA 2OZUA 2NU1I 4WP4A 5J8CA 3GOXA 2SGEI 2OVOA 1ULNA 2LUYA 3SEKC 3TOBA 4AMLA 1IW4A 2V1CC 1W4RA 1K7TA 1CT4I 1SGPI 1OMUA 2LB7A 1TBNA 2P6AC 5DAEA 1HEVA 1WTJA 3SGBI 1BUSA 2DIPA 1MJBA 2J9RA 2KMQA 2V1CA 1CSOI 2WGCA 3B4VC 1X4SA 1XA6A 3R5AA 4MPIA 4UXIA 5CCMA 2CWGA 1SGNI 2CWFA 2ELIA 2ROWA 3FC3A 3SGQI 4FKDA 1Z2IA 1FY7A 5FUXA 1V1IA 4B6DA 1R79A 2DKVA 1AN1I 4L9MA 5HI7A 1DS2I 5FUWA 5JHWC 1ULKA 1CT2I 2ERWA 2KCXA 1PCEA 2SGFI 2V53A 2N71A 2VRWB 1Z7KB 1FAQA 1KBEA 3UEJA 2N52A 1XBTA 2JZMA 2ODDA 2GKVA 2NU4I 3R5CA 2ORVA 1UVFA 2ORWA 3E59A 1KMAA 1FYBA 2NU2I 3UOEA 1LR9A 2GVIA 3KY9A 5E3RA 1MJ9A 3BJIA 1Q9BA 2GKRI 1CE3A 4OVOA 1ULMA 1P9ZA 3OXFA 2YQPA 3FSXA 4A24A 7WGAA 1TGSI 3RU0A 1X74A 3UEYA 2BUSA 1MT1A 1FARA 2E73A
chains in the Genus database with same CATH topology
1TBQR 2KMPA 1BMOA 2JW6A 2NU3I 4GI3C 2SGDI 1OVOA 3E2IA 3UFFA 1CGJI 1SGDI 1CGII 1YTPA 5FUVA 1PTQA 1Y1CA 1SGEI 1XX6A 3QWPA 2YUUA 1OMTA 1TIHA 2GKTI 3HH2C 4E1PA 2W0TA 3UGIA 2SGPI 2WVJA 2QQEA 1Y1BA 3SGBI 1H0ZA 1N13A 1YU6C 2KMOA 2ENNA 4UXJA 2N1AB 1LR7A 1PPFI 1KBFA 1CT0I 1LR8A 3CXLA 1TURA 3OVOA 3UGDA 3QTLD 1W3SA 1TOTA 2QPOA 1HJAI 3UGLA 1SGYI 1IY5A 1SGQI 1R0RI 1TUSA 2QQCA 4UXHA 2XRCA 1IY6A 5EX3A 2L8EA 2LEOA 1DS3I 2L7XA 2CJSC 1TBOA 1SGRI 3OXLA 2F3CI 1UVGA 2JYYA 2K9HA 3VDPA 1Y8FA 2ENZA 1V1HA 5HQ8A 1UUCA 2QQDA 3PDNA 3VE5A 2E5RA 1M8CA 2UZ3A 2J87A 1M8BA 1VDDA 2JXDA 2QQ0A 4E1RA 1PTRA 2N17A 5CCLA 2OD1A 2B0UC 3TJQA 2DB6A 2JA1A 2B8TA 1U5KA 4HGUA 3D00A 1TBRR 3OL0A 4JCVE 4SGBI 3VDUA 5FUYA 1HDLA 2WCYA 2A20A 1OYVI 2SGQI 2NU0I 3MEKA 2FNFX 5EX0A 1CHOI 2ARPF 1PJUA 1NUBA 3OXGA 2M5XA 1HPTA 1RFHA 2KMRA 3GOXA 2NU1I 2SGEI 2OVOA 3SEKC 2LUYA 1IW4A 2V1CC 1W4RA 5DAEA 1CT4I 1SGPI 1OMUA 2P6AC 1TBNA 1BUSA 2DIPA 3B4VC 2J9RA 2KMQA 2V1CA 1CSOI 5CCMA 1X4SA 1XA6A 4UXIA 2ELIA 1SGNI 2ROWA 3FC3A 3SGQI 4FKDA 5FUXA 1V1IA 4B6DA 1R79A 1AN1I 4L9MA 5HI7A 1DS2I 5FUWA 5JHWC 1CT2I 2ERWA 2KCXA 1PCEA 2SGFI 2V53A 2N71A 2VRWB 1Z7KB 1FAQA 1KBEA 3UEJA 2N52A 1XBTA 2JZMA 2ODDA 2GKVA 2NU4I 2ORVA 1UVFA 2ORWA 3E59A 1KMAA 1FYBA 2NU2I 1LR9A 2GVIA 3KY9A 3BJIA 2GKRI 1CE3A 4OVOA 3OXFA 2YQPA 4A24A 1TGSI 3RU0A 1X74A 3UEYA 2BUSA 1MT1A 1FARA 2E73A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TBQ R;  2KMP A;  1BMO A;  2NU3 I;  4GI3 C;  2SGD I;  1OVO A;  1CGJ I;  1SGD I;  1CGI I;  1YTP A;  1Y1C A;  1SGE I;  1OMT A;  1TIH A;  2GKT I;  3HH2 C;  2SGP I;  1Y1B A;  3SGB I;  1H0Z A;  1N13 A;  1YU6 C;  2KMO A;  1LR7 A;  1PPF I;  1MT1 A;  1CT0 I;  1LR8 A;  3OVO A;  1TUR A;  3QTL D;  1HJA I;  1SGY I;  1IY5 A;  1SGQ I;  1R0R I;  1TUS A;  2QQC A;  1IY6 A;  2XRC A;  2LEO A;  1DS3 I;  1SGR I;  2F3C I;  1UVG A;  2JYY A;  1UUC A;  2QQD A;  1M8C A;  1M8B A;  2JXD A;  2N17 A;  2B0U C;  3TJQ A;  4HGU A;  1TBR R;  4SGB I;  1HDL A;  2WCY A;  1OYV I;  2SGQ I;  2NU0 I;  1CHO I;  2ARP F;  1PJU A;  1NUB A;  1HPT A;  2KMR A;  2NU1 I;  2SGE I;  2OVO A;  3SEK C;  1IW4 A;  5DAE A;  1CT4 I;  1SGP I;  1OMU A;  2P6A C;  1BUS A;  3B4V C;  2KMQ A;  1CSO I;  1SGN I;  3SGQ I;  1AN1 I;  1DS2 I;  5JHW C;  1CT2 I;  2ERW A;  2KCX A;  1PCE A;  2SGF I;  2V53 A;  2N71 A;  1Z7K B;  2N52 A;  2JZM A;  2GKV A;  2NU4 I;  1UVF A;  1KMA A;  1FYB A;  2NU2 I;  1LR9 A;  2GKR I;  1CE3 A;  4OVO A;  1TGS I;  2BUS A;  2M5X A; 
#chains in the Genus database with same CATH topology
 3TO7 A;  1TBQ R;  2KMP A;  1BMO A;  1WKX A;  2JW6 A;  2NU3 I;  4GI3 C;  2SGD I;  1OVO A;  3E2I A;  3UFF A;  1CGJ I;  1SGD I;  1CGI I;  1S20 A;  1YTP A;  5FUV A;  3TOA A;  1PTQ A;  1Y1C A;  1SGE I;  1XX6 A;  3QAH A;  3QWP A;  2YUU A;  1OMT A;  1TIH A;  2GKT I;  3HH2 C;  4E1P A;  2W0T A;  3UGI A;  2SGP I;  2OU2 A;  2QQE A;  1K7V A;  1Y1B A;  2WVJ A;  2Y0M A;  3FSY A;  1K7U A;  1N13 A;  1YU6 C;  2ENN A;  2KMO A;  2X3T A;  4UXJ A;  2N1A B;  1H0Z A;  1WGC A;  1LR7 A;  1PPF I;  1CT0 I;  1LR8 A;  1KBF A;  3CXL A;  1TUR A;  3OVO A;  2PQ8 A;  3UGD A;  3QTL D;  1NXU A;  1W3S A;  1TOT A;  2QPO A;  1HJA I;  2RIJ A;  1SGY I;  3UGL A;  5E3P A;  1IY5 A;  1SGQ I;  1R0R I;  1TUS A;  2QQC A;  4UXH A;  2XRC A;  1IY6 A;  5EX3 A;  2GIV A;  1P9G A;  2L8E A;  2LEO A;  3TO9 A;  5J8F A;  1DS3 I;  2L7X A;  2CJS C;  1TBO A;  1SGR I;  3OXL A;  2F3C I;  1UVG A;  2JYY A;  2K9H A;  3R5D A;  3VDP A;  1Y8F A;  2ENZ A;  1V1H A;  5HQ8 A;  1UUC A;  5E3Q A;  2QQD A;  3PDN A;  3TO6 A;  3VE5 A;  2E5R A;  1M8C A;  2CWH A;  9WGA A;  2UZ3 A;  2J87 A;  1M8B A;  1WGT A;  1VDD A;  2JXD A;  1UHA A;  2QQ0 A;  2RC4 A;  4E1R A;  1PTR A;  2N17 A;  2X52 A;  2OD1 A;  2B0U C;  5CCL A;  3TJQ A;  1MJA A;  2DB6 A;  2JA1 A;  2UVO A;  2B8T A;  1U5K A;  4HGU A;  3D00 A;  1TBR R;  3OL0 A;  4JCV E;  4SGB I;  3VDU A;  5FUY A;  1HDL A;  2WCY A;  2A20 A;  1OYV I;  2SGQ I;  2NU0 I;  3MEK A;  2FNF X;  5EX0 A;  1CHO I;  3R5B A;  2ARP F;  1PJU A;  1NUB A;  3OXG A;  4DNC A;  2M5X A;  1HPT A;  1RFH A;  2KMR A;  2OZU A;  2NU1 I;  4WP4 A;  5J8C A;  3GOX A;  2SGE I;  2OVO A;  1ULN A;  2LUY A;  3SEK C;  3TOB A;  4AML A;  1IW4 A;  2V1C C;  1W4R A;  1K7T A;  1CT4 I;  1SGP I;  1OMU A;  2LB7 A;  1TBN A;  2P6A C;  5DAE A;  1HEV A;  1WTJ A;  3SGB I;  1BUS A;  2DIP A;  1MJB A;  2J9R A;  2KMQ A;  2V1C A;  1CSO I;  2WGC A;  3B4V C;  1X4S A;  1XA6 A;  3R5A A;  4MPI A;  4UXI A;  5CCM A;  2CWG A;  1SGN I;  2CWF A;  2ELI A;  2ROW A;  3FC3 A;  3SGQ I;  4FKD A;  1Z2I A;  1FY7 A;  5FUX A;  1V1I A;  4B6D A;  1R79 A;  2DKV A;  1AN1 I;  4L9M A;  5HI7 A;  1DS2 I;  5FUW A;  5JHW C;  1ULK A;  1CT2 I;  2ERW A;  2KCX A;  1PCE A;  2SGF I;  2V53 A;  2N71 A;  2VRW B;  1Z7K B;  1FAQ A;  1KBE A;  3UEJ A;  2N52 A;  1XBT A;  2JZM A;  2ODD A;  2GKV A;  2NU4 I;  3R5C A;  2ORV A;  1UVF A;  2ORW A;  3E59 A;  1KMA A;  1FYB A;  2NU2 I;  3UOE A;  1LR9 A;  2GVI A;  3KY9 A;  5E3R A;  1MJ9 A;  3BJI A;  1Q9B A;  2GKR I;  1CE3 A;  4OVO A;  1ULM A;  1P9Z A;  3OXF A;  2YQP A;  3FSX A;  4A24 A;  7WGA A;  1TGS I;  3RU0 A;  1X74 A;  3UEY A;  2BUS A;  1MT1 A;  1FAR A;  2E73 A; 
#chains in the Genus database with same CATH homology
 1TBQ R;  2KMP A;  1BMO A;  2JW6 A;  2NU3 I;  4GI3 C;  2SGD I;  1OVO A;  3E2I A;  3UFF A;  1CGJ I;  1SGD I;  1CGI I;  1YTP A;  5FUV A;  1PTQ A;  1Y1C A;  1SGE I;  1XX6 A;  3QWP A;  2YUU A;  1OMT A;  1TIH A;  2GKT I;  3HH2 C;  4E1P A;  2W0T A;  3UGI A;  2SGP I;  2WVJ A;  2QQE A;  1Y1B A;  3SGB I;  1H0Z A;  1N13 A;  1YU6 C;  2KMO A;  2ENN A;  4UXJ A;  2N1A B;  1LR7 A;  1PPF I;  1KBF A;  1CT0 I;  1LR8 A;  3CXL A;  1TUR A;  3OVO A;  3UGD A;  3QTL D;  1W3S A;  1TOT A;  2QPO A;  1HJA I;  3UGL A;  1SGY I;  1IY5 A;  1SGQ I;  1R0R I;  1TUS A;  2QQC A;  4UXH A;  2XRC A;  1IY6 A;  5EX3 A;  2L8E A;  2LEO A;  1DS3 I;  2L7X A;  2CJS C;  1TBO A;  1SGR I;  3OXL A;  2F3C I;  1UVG A;  2JYY A;  2K9H A;  3VDP A;  1Y8F A;  2ENZ A;  1V1H A;  5HQ8 A;  1UUC A;  2QQD A;  3PDN A;  3VE5 A;  2E5R A;  1M8C A;  2UZ3 A;  2J87 A;  1M8B A;  1VDD A;  2JXD A;  2QQ0 A;  4E1R A;  1PTR A;  2N17 A;  5CCL A;  2OD1 A;  2B0U C;  3TJQ A;  2DB6 A;  2JA1 A;  2B8T A;  1U5K A;  4HGU A;  3D00 A;  1TBR R;  3OL0 A;  4JCV E;  4SGB I;  3VDU A;  5FUY A;  1HDL A;  2WCY A;  2A20 A;  1OYV I;  2SGQ I;  2NU0 I;  3MEK A;  2FNF X;  5EX0 A;  1CHO I;  2ARP F;  1PJU A;  1NUB A;  3OXG A;  2M5X A;  1HPT A;  1RFH A;  2KMR A;  3GOX A;  2NU1 I;  2SGE I;  2OVO A;  3SEK C;  2LUY A;  1IW4 A;  2V1C C;  1W4R A;  5DAE A;  1CT4 I;  1SGP I;  1OMU A;  2P6A C;  1TBN A;  1BUS A;  2DIP A;  3B4V C;  2J9R A;  2KMQ A;  2V1C A;  1CSO I;  5CCM A;  1X4S A;  1XA6 A;  4UXI A;  2ELI A;  1SGN I;  2ROW A;  3FC3 A;  3SGQ I;  4FKD A;  5FUX A;  1V1I A;  4B6D A;  1R79 A;  1AN1 I;  4L9M A;  5HI7 A;  1DS2 I;  5FUW A;  5JHW C;  1CT2 I;  2ERW A;  2KCX A;  1PCE A;  2SGF I;  2V53 A;  2N71 A;  2VRW B;  1Z7K B;  1FAQ A;  1KBE A;  3UEJ A;  2N52 A;  1XBT A;  2JZM A;  2ODD A;  2GKV A;  2NU4 I;  2ORV A;  1UVF A;  2ORW A;  3E59 A;  1KMA A;  1FYB A;  2NU2 I;  1LR9 A;  2GVI A;  3KY9 A;  3BJI A;  2GKR I;  1CE3 A;  4OVO A;  3OXF A;  2YQP A;  4A24 A;  1TGS I;  3RU0 A;  1X74 A;  3UEY A;  2BUS A;  1MT1 A;  1FAR A;  2E73 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...