1UUCA

Solution structure of a chimeric lekti-domain
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
55
structure length
55
Chain Sequence
KNEDQEMCHEFQAFMKNGKLFCPQDKKPIQSLDGIMFINKCATCKMILEKEAKSQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Solution Structure of a Chimeric Lekti Domain Reveals a Chameleon Sequence
pubmed doi rcsb
molecule tags Serine proteinase inhibitor
source organism Homo sapiens
molecule keywords SERINE PROTEASE INHIBITOR KAZAL-TYPE 5
total genus 13
structure length 55
sequence length 55
ec nomenclature
pdb deposition date 2003-12-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1uucA00
2BUSA 2XRCA 1UVFA 1TUSA 2QQCA 1SGPI 1LR7A 1NUBA 1M8CA 1FYBA 1CT0I 2KMPA 1TBQR 4HGUA 1CSOI 1YTPA 2GKRI 4SGBI 1M8BA 2ERWA 1CGII 2F3CI 2KMRA 1BMOA 4GI3C 1CT2I 2SGPI 2GKVA 1HPTA 2SGQI 2KMOA 2M5XA 3SGBI 2KCXA 1PCEA 2WCYA 1LR8A 1DS3I 1OMTA 1IY6A 2ARPF 2JXDA 1DS2I 2P6AC 1LR9A 1BUSA 2B0UC 1OYVI 1OMUA 2NU4I 3TJQA 1KMAA 1N13A 1SGRI 2N71A 1Y1CA 1HJAI 2N17A 1HDLA 2KMQA 1TURA 2NU1I 2SGFI 5DAEA 1PPFI 1SGQI 1CE3A 3HH2C 1SGNI 1IY5A 1YU6C 1CT4I 2V53A 5JHWC 2OVOA 2NU3I 1TGSI 1SGDI 1CGJI 2SGEI 1TIHA 1OVOA 2SGDI 1UVGA 1Z7KB 2N52A 3SEKC 2GKTI 2JYYA 1R0RI 3SGQI 1SGYI 1UUCA 1H0ZA 1Y1BA 3B4VC 3OVOA 1SGEI 2LEOA 2NU0I 4OVOA 2NU2I 1PJUA 1CHOI 1AN1I 1MT1A 3QTLD 1IW4A 2JZMA 1TBRR 2QQDA
chains in the Genus database with same CATH superfamily
2BUSA 1K7UA 3QAHA 2UVOA 1UVFA 2XRCA 4L9MA 2L8EA 5EX0A 1TUSA 3TOAA 2QQCA 1SGPI 3TO9A 1PTRA 1TBNA 4E1RA 1UHAA 3TO6A 1LR7A 1Z2IA 2GVIA 1NUBA 3FSXA 4B6DA 3VDUA 1M8CA 1FYBA 4MPIA 5FUWA 1KBFA 2W0TA 1S20A 2QPOA 2CWHA 1MJAA 3R5AA 1CT0I 4E1PA 2KMPA 1TBOA 1TBQR 2LUYA 4HGUA 1W4RA 1Q9BA 1ULNA 4A24A 1CSOI 1ULMA 1YTPA 2DB6A 1P9ZA 3UGDA 3R5CA 5CCLA 2GKRI 5FUYA 4SGBI 3TOBA 5J8FA 1M8BA 2ERWA 2OU2A 3FSYA 2JA1A 2CWGA 1CGII 2E5RA 2E73A 2F3CI 2KMRA 1BMOA 1WKXA 1CT2I 2ROWA 2SGPI 4GI3C 2GKVA 2YUUA 1HPTA 2SGQI 2QQ0A 2RIJA 2KMOA 3TO7A 2M5XA 3SGBI 2KCXA 3E59A 2X3TA 1PCEA 2WCYA 1V1HA 1LR8A 1DS3I 1FAQA 1HEVA 1OMTA 4FKDA 1IY6A 2ARPF 2JXDA 1DS2I 3CXLA 2P6AC 5E3QA 1LR9A 2X52A 1KBEA 5E3RA 1BUSA 2B0UC 2DIPA 1OYVI 3UGIA 1OMUA 1WTJA 4UXHA 2J9RA 2NU4I 1ULKA 5J8CA 3TJQA 1RFHA 1N13A 1SGRI 1KMAA 2N71A 1V1IA 7WGAA 1Y1CA 1HJAI 1WGCA 2N17A 1P9GA 1Y8FA 2KMQA 1TURA 2OD1A 2RC4A 3VDPA 1HDLA 2NU1I 1NXUA 2SGFI 5DAEA 3OXLA 1PPFI 1SGQI 1CE3A 3UFFA 2L7XA 2DKVA 3HH2C 4WP4A 3D00A 2J87A 3VE5A 1K7TA 2JW6A 1SGNI 2ENZA 2FNFX 1IY5A 2Y0MA 4UXJA 5EX3A 1YU6C 1CT4I 2PQ8A 1X74A 3MEKA 2V53A 3OL0A 1FY7A 1XX6A 5JHWC 1MJ9A 2NU3I 2ODDA 2OVOA 2WGCA 1TGSI 2GIVA 2N1AB 1W3SA 1SGDI 3OXGA 1CGJI 3RU0A 2CWFA 3FC3A 2UZ3A 3GOXA 2SGEI 1PTQA 1TOTA 1TIHA 3BJIA 3QWPA 2YQPA 1OVOA 1MJBA 3E2IA 3KY9A 2SGDI 1UVGA 3UEJA 1Z7KB 2N52A 3SEKC 2ENNA 2GKTI 3UGLA 4DNCA 2JYYA 3R5DA 1VDDA 1R0RI 2VRWB 1WGTA 3UOEA 5HI7A 1SGYI 1UUCA 3SGQI 1U5KA 1H0ZA 1Y1BA 3B4VC 2CJSC 3OVOA 3R5BA 1SGEI 2LEOA 2NU0I 1R79A 5FUVA 1FARA 4OVOA 2NU2I 2ELIA 3PDNA 2V1CC 5FUXA 2WVJA 1PJUA 1CHOI 2V1CA 4UXIA 1AN1I 1MT1A 3UEYA 3QTLD 4AMLA 5HQ8A 1XA6A 1XBTA 2ORVA 2QQEA 2A20A 2ORWA 1IW4A 2B8TA 5CCMA 2JZMA 1X4SA 1TBRR 3OXFA 4JCVE 2QQDA 2LB7A 9WGAA 5E3PA 2OZUA 1K7VA 2K9HA
chains in the Genus database with same CATH topology
2BUSA 2XRCA 1UVFA 4L9MA 2L8EA 5EX0A 1TUSA 2QQCA 1SGPI 1PTRA 1TBNA 4E1RA 1LR7A 2GVIA 1NUBA 4B6DA 3VDUA 1M8CA 1FYBA 5FUWA 1KBFA 2W0TA 2QPOA 4E1PA 1CT0I 2KMPA 1TBOA 1TBQR 2LUYA 4HGUA 1W4RA 4A24A 1CSOI 1YTPA 2DB6A 3UGDA 5CCLA 2GKRI 5FUYA 4SGBI 1M8BA 2ERWA 2JA1A 1CGII 2E5RA 2E73A 2F3CI 2KMRA 1BMOA 4GI3C 1CT2I 2ROWA 2SGPI 2GKVA 2YUUA 1HPTA 2SGQI 2QQ0A 2KMOA 2M5XA 3SGBI 2KCXA 1PCEA 2WCYA 1V1HA 1LR8A 1DS3I 1FAQA 1OMTA 4FKDA 1IY6A 2ARPF 2JXDA 1DS2I 3CXLA 2P6AC 1LR9A 1KBEA 1BUSA 2B0UC 2DIPA 1OYVI 3UGIA 1OMUA 4UXHA 2J9RA 2NU4I 3TJQA 1RFHA 1N13A 1SGRI 1KMAA 2N71A 1V1IA 1Y1CA 1HJAI 2N17A 1HDLA 1Y8FA 2KMQA 1TURA 2OD1A 3VDPA 2NU1I 2SGFI 5DAEA 3OXLA 1PPFI 1SGQI 1CE3A 3UFFA 2L7XA 3HH2C 3VE5A 3D00A 2J87A 2JW6A 1SGNI 2ENZA 2FNFX 1IY5A 4UXJA 5EX3A 1YU6C 1CT4I 3MEKA 1X74A 2V53A 3OL0A 1XX6A 5JHWC 2OVOA 2NU3I 2ODDA 1TGSI 3RU0A 2N1AB 1W3SA 1SGDI 3OXGA 1CGJI 3FC3A 2UZ3A 3GOXA 2SGEI 1PTQA 1TOTA 1TIHA 3BJIA 3QWPA 2YQPA 1OVOA 3E2IA 3KY9A 2SGDI 1UVGA 3UEJA 1Z7KB 2N52A 3SEKC 2ENNA 2GKTI 3UGLA 2JYYA 1VDDA 1R0RI 2VRWB 5HI7A 1SGYI 1UUCA 3SGQI 1U5KA 1H0ZA 1Y1BA 3B4VC 2CJSC 3OVOA 1SGEI 2LEOA 2NU0I 1R79A 5FUVA 1FARA 4OVOA 2NU2I 2ELIA 3PDNA 2V1CC 5FUXA 2WVJA 1PJUA 1CHOI 2V1CA 4UXIA 1AN1I 1MT1A 3UEYA 3QTLD 5HQ8A 1XA6A 1XBTA 2ORVA 2QQEA 2A20A 2ORWA 1IW4A 2B8TA 5CCMA 2JZMA 1X4SA 1TBRR 3OXFA 4JCVE 2QQDA 3E59A 2K9HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BUS A;  2XRC A;  1UVF A;  1TUS A;  2QQC A;  1SGP I;  1LR7 A;  1NUB A;  1M8C A;  1FYB A;  1CT0 I;  2KMP A;  1TBQ R;  4HGU A;  1CSO I;  1YTP A;  2GKR I;  4SGB I;  1M8B A;  2ERW A;  1CGI I;  2F3C I;  2KMR A;  1BMO A;  4GI3 C;  1CT2 I;  2SGP I;  2GKV A;  1HPT A;  2SGQ I;  2KMO A;  2M5X A;  3SGB I;  2KCX A;  1PCE A;  2WCY A;  1LR8 A;  1DS3 I;  1OMT A;  1IY6 A;  2ARP F;  2JXD A;  1DS2 I;  2P6A C;  1LR9 A;  1BUS A;  2B0U C;  1OYV I;  1OMU A;  2NU4 I;  3TJQ A;  1KMA A;  1N13 A;  1SGR I;  2N71 A;  1Y1C A;  1HJA I;  2N17 A;  1HDL A;  2KMQ A;  1TUR A;  2NU1 I;  2SGF I;  5DAE A;  1PPF I;  1SGQ I;  1CE3 A;  3HH2 C;  1SGN I;  1IY5 A;  1YU6 C;  1CT4 I;  2V53 A;  5JHW C;  2OVO A;  2NU3 I;  1TGS I;  1SGD I;  1CGJ I;  2SGE I;  1TIH A;  1OVO A;  2SGD I;  1UVG A;  1Z7K B;  2N52 A;  3SEK C;  2GKT I;  2JYY A;  1R0R I;  3SGQ I;  1SGY I;  1UUC A;  1H0Z A;  1Y1B A;  3B4V C;  3OVO A;  1SGE I;  2LEO A;  2NU0 I;  4OVO A;  2NU2 I;  1PJU A;  1CHO I;  1AN1 I;  1MT1 A;  3QTL D;  1IW4 A;  2JZM A;  1TBR R;  2QQD A; 
#chains in the Genus database with same CATH topology
 2BUS A;  1K7U A;  3QAH A;  2UVO A;  1UVF A;  2XRC A;  4L9M A;  2L8E A;  5EX0 A;  1TUS A;  3TOA A;  2QQC A;  1SGP I;  3TO9 A;  1PTR A;  1TBN A;  4E1R A;  1UHA A;  3TO6 A;  1LR7 A;  1Z2I A;  2GVI A;  1NUB A;  3FSX A;  4B6D A;  3VDU A;  1M8C A;  1FYB A;  4MPI A;  5FUW A;  1KBF A;  2W0T A;  1S20 A;  2QPO A;  2CWH A;  1MJA A;  3R5A A;  1CT0 I;  4E1P A;  2KMP A;  1TBO A;  1TBQ R;  2LUY A;  4HGU A;  1W4R A;  1Q9B A;  1ULN A;  4A24 A;  1CSO I;  1ULM A;  1YTP A;  2DB6 A;  1P9Z A;  3UGD A;  3R5C A;  5CCL A;  2GKR I;  5FUY A;  4SGB I;  3TOB A;  5J8F A;  1M8B A;  2ERW A;  2OU2 A;  3FSY A;  2JA1 A;  2CWG A;  1CGI I;  2E5R A;  2E73 A;  2F3C I;  2KMR A;  1BMO A;  1WKX A;  1CT2 I;  2ROW A;  2SGP I;  4GI3 C;  2GKV A;  2YUU A;  1HPT A;  2SGQ I;  2QQ0 A;  2RIJ A;  2KMO A;  3TO7 A;  2M5X A;  3SGB I;  2KCX A;  3E59 A;  2X3T A;  1PCE A;  2WCY A;  1V1H A;  1LR8 A;  1DS3 I;  1FAQ A;  1HEV A;  1OMT A;  4FKD A;  1IY6 A;  2ARP F;  2JXD A;  1DS2 I;  3CXL A;  2P6A C;  5E3Q A;  1LR9 A;  2X52 A;  1KBE A;  5E3R A;  1BUS A;  2B0U C;  2DIP A;  1OYV I;  3UGI A;  1OMU A;  1WTJ A;  4UXH A;  2J9R A;  2NU4 I;  1ULK A;  5J8C A;  3TJQ A;  1RFH A;  1N13 A;  1SGR I;  1KMA A;  2N71 A;  1V1I A;  7WGA A;  1Y1C A;  1HJA I;  1WGC A;  2N17 A;  1P9G A;  1Y8F A;  2KMQ A;  1TUR A;  2OD1 A;  2RC4 A;  3VDP A;  1HDL A;  2NU1 I;  1NXU A;  2SGF I;  5DAE A;  3OXL A;  1PPF I;  1SGQ I;  1CE3 A;  3UFF A;  2L7X A;  2DKV A;  3HH2 C;  4WP4 A;  3D00 A;  2J87 A;  3VE5 A;  1K7T A;  2JW6 A;  1SGN I;  2ENZ A;  2FNF X;  1IY5 A;  2Y0M A;  4UXJ A;  5EX3 A;  1YU6 C;  1CT4 I;  2PQ8 A;  1X74 A;  3MEK A;  2V53 A;  3OL0 A;  1FY7 A;  1XX6 A;  5JHW C;  1MJ9 A;  2NU3 I;  2ODD A;  2OVO A;  2WGC A;  1TGS I;  2GIV A;  2N1A B;  1W3S A;  1SGD I;  3OXG A;  1CGJ I;  3RU0 A;  2CWF A;  3FC3 A;  2UZ3 A;  3GOX A;  2SGE I;  1PTQ A;  1TOT A;  1TIH A;  3BJI A;  3QWP A;  2YQP A;  1OVO A;  1MJB A;  3E2I A;  3KY9 A;  2SGD I;  1UVG A;  3UEJ A;  1Z7K B;  2N52 A;  3SEK C;  2ENN A;  2GKT I;  3UGL A;  4DNC A;  2JYY A;  3R5D A;  1VDD A;  1R0R I;  2VRW B;  1WGT A;  3UOE A;  5HI7 A;  1SGY I;  1UUC A;  3SGQ I;  1U5K A;  1H0Z A;  1Y1B A;  3B4V C;  2CJS C;  3OVO A;  3R5B A;  1SGE I;  2LEO A;  2NU0 I;  1R79 A;  5FUV A;  1FAR A;  4OVO A;  2NU2 I;  2ELI A;  3PDN A;  2V1C C;  5FUX A;  2WVJ A;  1PJU A;  1CHO I;  2V1C A;  4UXI A;  1AN1 I;  1MT1 A;  3UEY A;  3QTL D;  4AML A;  5HQ8 A;  1XA6 A;  1XBT A;  2ORV A;  2QQE A;  2A20 A;  2ORW A;  1IW4 A;  2B8T A;  5CCM A;  2JZM A;  1X4S A;  1TBR R;  3OXF A;  4JCV E;  2QQD A;  2LB7 A;  9WGA A;  5E3P A;  2OZU A;  1K7V A;  2K9H A; 
#chains in the Genus database with same CATH homology
 2BUS A;  2XRC A;  1UVF A;  4L9M A;  2L8E A;  5EX0 A;  1TUS A;  2QQC A;  1SGP I;  1PTR A;  1TBN A;  4E1R A;  1LR7 A;  2GVI A;  1NUB A;  4B6D A;  3VDU A;  1M8C A;  1FYB A;  5FUW A;  1KBF A;  2W0T A;  2QPO A;  4E1P A;  1CT0 I;  2KMP A;  1TBO A;  1TBQ R;  2LUY A;  4HGU A;  1W4R A;  4A24 A;  1CSO I;  1YTP A;  2DB6 A;  3UGD A;  5CCL A;  2GKR I;  5FUY A;  4SGB I;  1M8B A;  2ERW A;  2JA1 A;  1CGI I;  2E5R A;  2E73 A;  2F3C I;  2KMR A;  1BMO A;  4GI3 C;  1CT2 I;  2ROW A;  2SGP I;  2GKV A;  2YUU A;  1HPT A;  2SGQ I;  2QQ0 A;  2KMO A;  2M5X A;  3SGB I;  2KCX A;  1PCE A;  2WCY A;  1V1H A;  1LR8 A;  1DS3 I;  1FAQ A;  1OMT A;  4FKD A;  1IY6 A;  2ARP F;  2JXD A;  1DS2 I;  3CXL A;  2P6A C;  1LR9 A;  1KBE A;  1BUS A;  2B0U C;  2DIP A;  1OYV I;  3UGI A;  1OMU A;  4UXH A;  2J9R A;  2NU4 I;  3TJQ A;  1RFH A;  1N13 A;  1SGR I;  1KMA A;  2N71 A;  1V1I A;  1Y1C A;  1HJA I;  2N17 A;  1HDL A;  1Y8F A;  2KMQ A;  1TUR A;  2OD1 A;  3VDP A;  2NU1 I;  2SGF I;  5DAE A;  3OXL A;  1PPF I;  1SGQ I;  1CE3 A;  3UFF A;  2L7X A;  3HH2 C;  3VE5 A;  3D00 A;  2J87 A;  2JW6 A;  1SGN I;  2ENZ A;  2FNF X;  1IY5 A;  4UXJ A;  5EX3 A;  1YU6 C;  1CT4 I;  3MEK A;  1X74 A;  2V53 A;  3OL0 A;  1XX6 A;  5JHW C;  2OVO A;  2NU3 I;  2ODD A;  1TGS I;  3RU0 A;  2N1A B;  1W3S A;  1SGD I;  3OXG A;  1CGJ I;  3FC3 A;  2UZ3 A;  3GOX A;  2SGE I;  1PTQ A;  1TOT A;  1TIH A;  3BJI A;  3QWP A;  2YQP A;  1OVO A;  3E2I A;  3KY9 A;  2SGD I;  1UVG A;  3UEJ A;  1Z7K B;  2N52 A;  3SEK C;  2ENN A;  2GKT I;  3UGL A;  2JYY A;  1VDD A;  1R0R I;  2VRW B;  5HI7 A;  1SGY I;  1UUC A;  3SGQ I;  1U5K A;  1H0Z A;  1Y1B A;  3B4V C;  2CJS C;  3OVO A;  1SGE I;  2LEO A;  2NU0 I;  1R79 A;  5FUV A;  1FAR A;  4OVO A;  2NU2 I;  2ELI A;  3PDN A;  2V1C C;  5FUX A;  2WVJ A;  1PJU A;  1CHO I;  2V1C A;  4UXI A;  1AN1 I;  1MT1 A;  3UEY A;  3QTL D;  5HQ8 A;  1XA6 A;  1XBT A;  2ORV A;  2QQE A;  2A20 A;  2ORW A;  1IW4 A;  2B8T A;  5CCM A;  2JZM A;  1X4S A;  1TBR R;  3OXF A;  4JCV E;  2QQD A;  3E59 A;  2K9H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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