1Y8FA

Solution structure of the munc13-1 c1-domain
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
51
structure length
51
Chain Sequence
QHNFEVWTATTPTYCYECEGLLWGIARQGMRCTECGVKCHEKCQDLLNADC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Endocytosis/exocytosis,signaling protein
source organism Rattus norvegicus
publication title Intramolecular occlusion of the diacylglycerol-binding site in the C1 domain of munc13-1.
pubmed doi rcsb
molecule keywords Unc-13 homolog A
total genus 5
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 2004-12-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.20 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1y8fA00
1XX6A 2ENNA 1KBEA 1RFHA 1R79A 1TBNA 4UXIA 2FNFX 5FUXA 4UXHA 2ELIA 1XA6A 2VRWB 3UEYA 2E73A 4L9MA 1Y8FA 2GVIA 2ROWA 2QQEA 1XBTA 3UGLA 1FARA 5FUWA 5FUVA 1FAQA 1KBFA 1W4RA 2UZ3A 3BJIA 4FKDA 2QPOA 1TBOA 2YUUA 3UGIA 3UFFA 2J9RA 2B8TA 3KY9A 2J87A 4UXJA 3UGDA 2ORVA 4B6DA 1PTRA 2QQ0A 3E2IA 2WVJA 2ORWA 2DB6A 1PTQA 2ENZA 3CXLA 3UEJA 5FUYA 2JA1A
chains in the Genus database with same CATH superfamily
1XX6A 2N1AB 1VDDA 2ERWA 5J8FA 5FUXA 3B4VC 2DKVA 1TIHA 4UXHA 2V1CA 2GKVA 1CSOI 1P9ZA 3QAHA 4L9MA 1NUBA 3TO9A 2GVIA 3OVOA 5E3QA 2SGEI 3UGLA 3R5BA 1FY7A 2CWHA 1Z7KB 2L7XA 2ARPF 1V1IA 1BMOA 2CWGA 2UZ3A 3TO7A 1K7VA 1MJ9A 3RU0A 1SGQI 2QPOA 1ULNA 2NU1I 2KMOA 2JZMA 3SGQI 1V1HA 1LR9A 2GKRI 1MT1A 3KY9A 2M5XA 2SGQI 3UGDA 4DNCA 1IY5A 3R5DA 3TO6A 2QQ0A 3E2IA 1M8BA 4A24A 5CCMA 3FSXA 2K9HA 1W3SA 2OVOA 3MEKA 3R5CA 3TOAA 5FUYA 3UEJA 1UVGA 3TJQA 3SGBI 2DIPA 1KBEA 1MJBA 3SEKC 1TBNA 4UXIA 2QQCA 1M8CA 2CWFA 2ELIA 1XA6A 2A20A 2QQDA 1PPFI 1SGEI 3UEYA 2X3TA 5FUVA 2F3CI 1BUSA 5JHWC 2SGPI 1FYBA 2XRCA 1U5KA 3UOEA 2PQ8A 4FKDA 2JXDA 2P6AC 2LB7A 1OYVI 2OD1A 1PJUA 1TBQR 2YUUA 3UGIA 1X4SA 2JYYA 3QWPA 1Y1CA 2BUSA 4GI3C 3FC3A 3GOXA 1OMUA 1WKXA 5DAEA 5EX0A 2W0TA 1SGRI 4UXJA 1H0ZA 5E3RA 1CT0I 2X52A 1N13A 4HGUA 1PCEA 1UVFA 2ORWA 2L8EA 1OVOA 1Q9BA 1SGNI 3CXLA 2RC4A 1LR8A 2GKTI 2JA1A 1CT2I 1MJAA 2ENNA 1SGPI 1RFHA 1IY6A 1R79A 1UHAA 1DS3I 2FNFX 1HJAI 2N17A 1KMAA 2KMRA 1ULKA 2E73A 3PDNA 2ROWA 1TURA 1HPTA 1XBTA 2QQEA 5FUWA 5HI7A 1WTJA 1YTPA 4WP4A 5E3PA 1HEVA 1W4RA 2V53A 2V1CC 1IW4A 1CGII 2ODDA 2KMPA 2JW6A 1Z2IA 3OXGA 3TOBA 1YU6C 2KCXA 2WCYA 2RIJA 2B0UC 2J87A 3OXLA 3VDUA 2ORVA 4B6DA 4SGBI 1SGDI 2WVJA 1LR7A 4E1RA 1R0RI 5CCLA 1CT4I 1WGCA 2NU3I 1K7UA 1UUCA 2SGFI 4AMLA 4E1PA 1DS2I 2YQPA 3R5AA 2LEOA 5EX3A 2NU0I 2GIVA 1TUSA 2VRWB 3VE5A 1Y8FA 1OMTA 3QTLD 1NXUA 1FARA 1CGJI 2NU4I 3D00A 4MPIA 1FAQA 1KBFA 2N71A 1Y1BA 2LUYA 3E59A 1S20A 1TBRR 1WGTA 3BJIA 2SGDI 9WGAA 5J8CA 3VDPA 3HH2C 5HQ8A 1TBOA 1TOTA 2E5RA 2WGCA 3UFFA 2J9RA 2OZUA 7WGAA 3OL0A 1P9GA 1CHOI 1SGYI 2B8TA 2N52A 3OXFA 1K7TA 2OU2A 2Y0MA 1PTRA 2UVOA 3FSYA 4OVOA 1AN1I 1ULMA 1PTQA 2DB6A 2CJSC 2ENZA 1X74A 2KMQA 1CE3A 4JCVE 1HDLA 1TGSI 2NU2I
chains in the Genus database with same CATH topology
1XX6A 2N1AB 1VDDA 2ERWA 5FUXA 3B4VC 1TIHA 4UXHA 2V1CA 2GKVA 1CSOI 4L9MA 1NUBA 2GVIA 3OVOA 3UGLA 2SGEI 2L7XA 1Z7KB 2ARPF 1V1IA 1BMOA 2UZ3A 3RU0A 1SGQI 2QPOA 2NU1I 2KMOA 2JZMA 3SGQI 1V1HA 1LR9A 2GKRI 1MT1A 3KY9A 2M5XA 2SGQI 3UGDA 1IY5A 2QQ0A 3E2IA 1M8BA 4A24A 5CCMA 2K9HA 1W3SA 2OVOA 3MEKA 3UEJA 5FUYA 1UVGA 3TJQA 3SGBI 2DIPA 1KBEA 3SEKC 1TBNA 4UXIA 2QQCA 1M8CA 2ELIA 1XA6A 2A20A 2QQDA 1PPFI 1SGEI 3UEYA 5FUVA 2F3CI 1BUSA 5JHWC 2SGPI 1FYBA 2XRCA 1U5KA 4FKDA 2JXDA 2P6AC 1OYVI 2OD1A 1PJUA 1TBQR 2YUUA 3UGIA 1X4SA 2JYYA 3QWPA 1Y1CA 2BUSA 4GI3C 3FC3A 3GOXA 1OMUA 5DAEA 1H0ZA 5EX0A 2W0TA 1SGRI 4UXJA 1CT0I 1N13A 4HGUA 1PCEA 1UVFA 2ORWA 2L8EA 1OVOA 1SGNI 3CXLA 1LR8A 2GKTI 2JA1A 1CT2I 2ENNA 1SGPI 1RFHA 1IY6A 1R79A 1DS3I 2FNFX 1HJAI 2N17A 1KMAA 2KMRA 2E73A 3PDNA 2ROWA 1TURA 1HPTA 1XBTA 2QQEA 5FUWA 5HI7A 1YTPA 1W4RA 2V53A 2V1CC 1IW4A 1CGII 2ODDA 2KMPA 2JW6A 3OXGA 1YU6C 2KCXA 2WCYA 2B0UC 2J87A 3OXLA 3VDUA 2ORVA 4B6DA 4SGBI 1SGDI 2WVJA 1LR7A 4E1RA 1R0RI 5CCLA 1CT4I 4E1PA 2NU3I 1UUCA 2SGFI 1DS2I 2YQPA 2LEOA 5EX3A 2NU0I 1TUSA 2VRWB 3VE5A 1Y8FA 1OMTA 3QTLD 1FARA 1CGJI 2NU4I 3D00A 1FAQA 1KBFA 2N71A 1Y1BA 2LUYA 3E59A 1TBRR 3BJIA 2SGDI 3VDPA 3HH2C 5HQ8A 1TBOA 1TOTA 2E5RA 3UFFA 2J9RA 3OL0A 1CHOI 1SGYI 2B8TA 2N52A 3OXFA 1PTRA 4OVOA 1AN1I 2DB6A 1PTQA 2ENZA 2CJSC 1X74A 2KMQA 1CE3A 4JCVE 1HDLA 1TGSI 2NU2I
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XX6 A;  2ENN A;  1KBE A;  1RFH A;  1R79 A;  1TBN A;  4UXI A;  2FNF X;  5FUX A;  4UXH A;  2ELI A;  1XA6 A;  2VRW B;  3UEY A;  2E73 A;  4L9M A;  1Y8F A;  2GVI A;  2ROW A;  2QQE A;  1XBT A;  3UGL A;  1FAR A;  5FUW A;  5FUV A;  1FAQ A;  1KBF A;  1W4R A;  2UZ3 A;  3BJI A;  4FKD A;  2QPO A;  1TBO A;  2YUU A;  3UGI A;  3UFF A;  2J9R A;  2B8T A;  3KY9 A;  2J87 A;  4UXJ A;  3UGD A;  2ORV A;  4B6D A;  1PTR A;  2QQ0 A;  3E2I A;  2WVJ A;  2ORW A;  2DB6 A;  1PTQ A;  2ENZ A;  3CXL A;  3UEJ A;  5FUY A;  2JA1 A; 
#chains in the Genus database with same CATH topology
 1XX6 A;  2N1A B;  1VDD A;  2ERW A;  5J8F A;  5FUX A;  3B4V C;  2DKV A;  1TIH A;  4UXH A;  2V1C A;  2GKV A;  1CSO I;  1P9Z A;  3QAH A;  4L9M A;  1NUB A;  3TO9 A;  2GVI A;  3OVO A;  5E3Q A;  2SGE I;  3UGL A;  3R5B A;  1FY7 A;  2CWH A;  1Z7K B;  2L7X A;  2ARP F;  1V1I A;  1BMO A;  2CWG A;  2UZ3 A;  3TO7 A;  1K7V A;  1MJ9 A;  3RU0 A;  1SGQ I;  2QPO A;  1ULN A;  2NU1 I;  2KMO A;  2JZM A;  3SGQ I;  1V1H A;  1LR9 A;  2GKR I;  1MT1 A;  3KY9 A;  2M5X A;  2SGQ I;  3UGD A;  4DNC A;  1IY5 A;  3R5D A;  3TO6 A;  2QQ0 A;  3E2I A;  1M8B A;  4A24 A;  5CCM A;  3FSX A;  2K9H A;  1W3S A;  2OVO A;  3MEK A;  3R5C A;  3TOA A;  5FUY A;  3UEJ A;  1UVG A;  3TJQ A;  3SGB I;  2DIP A;  1KBE A;  1MJB A;  3SEK C;  1TBN A;  4UXI A;  2QQC A;  1M8C A;  2CWF A;  2ELI A;  1XA6 A;  2A20 A;  2QQD A;  1PPF I;  1SGE I;  3UEY A;  2X3T A;  5FUV A;  2F3C I;  1BUS A;  5JHW C;  2SGP I;  1FYB A;  2XRC A;  1U5K A;  3UOE A;  2PQ8 A;  4FKD A;  2JXD A;  2P6A C;  2LB7 A;  1OYV I;  2OD1 A;  1PJU A;  1TBQ R;  2YUU A;  3UGI A;  1X4S A;  2JYY A;  3QWP A;  1Y1C A;  2BUS A;  4GI3 C;  3FC3 A;  3GOX A;  1OMU A;  1WKX A;  5DAE A;  5EX0 A;  2W0T A;  1SGR I;  4UXJ A;  1H0Z A;  5E3R A;  1CT0 I;  2X52 A;  1N13 A;  4HGU A;  1PCE A;  1UVF A;  2ORW A;  2L8E A;  1OVO A;  1Q9B A;  1SGN I;  3CXL A;  2RC4 A;  1LR8 A;  2GKT I;  2JA1 A;  1CT2 I;  1MJA A;  2ENN A;  1SGP I;  1RFH A;  1IY6 A;  1R79 A;  1UHA A;  1DS3 I;  2FNF X;  1HJA I;  2N17 A;  1KMA A;  2KMR A;  1ULK A;  2E73 A;  3PDN A;  2ROW A;  1TUR A;  1HPT A;  1XBT A;  2QQE A;  5FUW A;  5HI7 A;  1WTJ A;  1YTP A;  4WP4 A;  5E3P A;  1HEV A;  1W4R A;  2V53 A;  2V1C C;  1IW4 A;  1CGI I;  2ODD A;  2KMP A;  2JW6 A;  1Z2I A;  3OXG A;  3TOB A;  1YU6 C;  2KCX A;  2WCY A;  2RIJ A;  2B0U C;  2J87 A;  3OXL A;  3VDU A;  2ORV A;  4B6D A;  4SGB I;  1SGD I;  2WVJ A;  1LR7 A;  4E1R A;  1R0R I;  5CCL A;  1CT4 I;  1WGC A;  2NU3 I;  1K7U A;  1UUC A;  2SGF I;  4AML A;  4E1P A;  1DS2 I;  2YQP A;  3R5A A;  2LEO A;  5EX3 A;  2NU0 I;  2GIV A;  1TUS A;  2VRW B;  3VE5 A;  1Y8F A;  1OMT A;  3QTL D;  1NXU A;  1FAR A;  1CGJ I;  2NU4 I;  3D00 A;  4MPI A;  1FAQ A;  1KBF A;  2N71 A;  1Y1B A;  2LUY A;  3E59 A;  1S20 A;  1TBR R;  1WGT A;  3BJI A;  2SGD I;  9WGA A;  5J8C A;  3VDP A;  3HH2 C;  5HQ8 A;  1TBO A;  1TOT A;  2E5R A;  2WGC A;  3UFF A;  2J9R A;  2OZU A;  7WGA A;  3OL0 A;  1P9G A;  1CHO I;  1SGY I;  2B8T A;  2N52 A;  3OXF A;  1K7T A;  2OU2 A;  2Y0M A;  1PTR A;  2UVO A;  3FSY A;  4OVO A;  1AN1 I;  1ULM A;  1PTQ A;  2DB6 A;  2CJS C;  2ENZ A;  1X74 A;  2KMQ A;  1CE3 A;  4JCV E;  1HDL A;  1TGS I;  2NU2 I; 
#chains in the Genus database with same CATH homology
 1XX6 A;  2N1A B;  1VDD A;  2ERW A;  5FUX A;  3B4V C;  1TIH A;  4UXH A;  2V1C A;  2GKV A;  1CSO I;  4L9M A;  1NUB A;  2GVI A;  3OVO A;  3UGL A;  2SGE I;  2L7X A;  1Z7K B;  2ARP F;  1V1I A;  1BMO A;  2UZ3 A;  3RU0 A;  1SGQ I;  2QPO A;  2NU1 I;  2KMO A;  2JZM A;  3SGQ I;  1V1H A;  1LR9 A;  2GKR I;  1MT1 A;  3KY9 A;  2M5X A;  2SGQ I;  3UGD A;  1IY5 A;  2QQ0 A;  3E2I A;  1M8B A;  4A24 A;  5CCM A;  2K9H A;  1W3S A;  2OVO A;  3MEK A;  3UEJ A;  5FUY A;  1UVG A;  3TJQ A;  3SGB I;  2DIP A;  1KBE A;  3SEK C;  1TBN A;  4UXI A;  2QQC A;  1M8C A;  2ELI A;  1XA6 A;  2A20 A;  2QQD A;  1PPF I;  1SGE I;  3UEY A;  5FUV A;  2F3C I;  1BUS A;  5JHW C;  2SGP I;  1FYB A;  2XRC A;  1U5K A;  4FKD A;  2JXD A;  2P6A C;  1OYV I;  2OD1 A;  1PJU A;  1TBQ R;  2YUU A;  3UGI A;  1X4S A;  2JYY A;  3QWP A;  1Y1C A;  2BUS A;  4GI3 C;  3FC3 A;  3GOX A;  1OMU A;  5DAE A;  1H0Z A;  5EX0 A;  2W0T A;  1SGR I;  4UXJ A;  1CT0 I;  1N13 A;  4HGU A;  1PCE A;  1UVF A;  2ORW A;  2L8E A;  1OVO A;  1SGN I;  3CXL A;  1LR8 A;  2GKT I;  2JA1 A;  1CT2 I;  2ENN A;  1SGP I;  1RFH A;  1IY6 A;  1R79 A;  1DS3 I;  2FNF X;  1HJA I;  2N17 A;  1KMA A;  2KMR A;  2E73 A;  3PDN A;  2ROW A;  1TUR A;  1HPT A;  1XBT A;  2QQE A;  5FUW A;  5HI7 A;  1YTP A;  1W4R A;  2V53 A;  2V1C C;  1IW4 A;  1CGI I;  2ODD A;  2KMP A;  2JW6 A;  3OXG A;  1YU6 C;  2KCX A;  2WCY A;  2B0U C;  2J87 A;  3OXL A;  3VDU A;  2ORV A;  4B6D A;  4SGB I;  1SGD I;  2WVJ A;  1LR7 A;  4E1R A;  1R0R I;  5CCL A;  1CT4 I;  4E1P A;  2NU3 I;  1UUC A;  2SGF I;  1DS2 I;  2YQP A;  2LEO A;  5EX3 A;  2NU0 I;  1TUS A;  2VRW B;  3VE5 A;  1Y8F A;  1OMT A;  3QTL D;  1FAR A;  1CGJ I;  2NU4 I;  3D00 A;  1FAQ A;  1KBF A;  2N71 A;  1Y1B A;  2LUY A;  3E59 A;  1TBR R;  3BJI A;  2SGD I;  3VDP A;  3HH2 C;  5HQ8 A;  1TBO A;  1TOT A;  2E5R A;  3UFF A;  2J9R A;  3OL0 A;  1CHO I;  1SGY I;  2B8T A;  2N52 A;  3OXF A;  1PTR A;  4OVO A;  1AN1 I;  2DB6 A;  1PTQ A;  2ENZ A;  2CJS C;  1X74 A;  2KMQ A;  1CE3 A;  4JCV E;  1HDL A;  1TGS I;  2NU2 I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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