1YTPA

Solution structure of the c4a/c41a variant of the nicotiana alata proteinase inhibitor t1
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
53
structure length
53
Chain Sequence
DRIATNCCAGTKGCKYFSDDGTFVCEGESDPRNPKACPRNADPRIAYGICPLA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of a disulfide mutant of the Nicotiana alata proteinase inhibitor T1 --- Stabilisation of the reactive site loop is critical for activity
rcsb
molecule tags Hydrolase inhibitor
source organism Nicotiana alata
molecule keywords proteinase inhibitor
total genus 10
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2005-02-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1ytpA00
2M5XA 2SGQI 1SGYI 4HGUA 1DS3I 1SGDI 1KMAA 1TGSI 2QQCA 1LR9A 2LEOA 2NU2I 1NUBA 1IY5A 3TJQA 1UUCA 2GKVA 1UVFA 2ARPF 2KMOA 2NU1I 1PCEA 1LR8A 1CT0I 1MT1A 2NU3I 2SGDI 1HDLA 1TBQR 2KCXA 2JXDA 1CGJI 1DS2I 4SGBI 1R0RI 3SGBI 2KMRA 4OVOA 1FYBA 1Y1CA 2SGFI 2XRCA 2JZMA 1TBRR 3HH2C 1TIHA 3SGQI 2B0UC 3B4VC 1N13A 1Z7KB 3OVOA 2BUSA 2F3CI 1M8CA 1CSOI 1IY6A 1SGQI 2JYYA 1YU6C 2NU0I 5JHWC 2NU4I 1SGEI 5DAEA 1BUSA 1HPTA 1SGNI 1CT4I 2N52A 1CE3A 1HJAI 1IW4A 2N17A 1YTPA 1CT2I 2SGPI 2ERWA 2KMQA 4GI3C 1UVGA 2WCYA 1M8BA 2GKRI 1OMUA 1Y1BA 1CHOI 1BMOA 1OYVI 2OVOA 1CGII 1SGRI 2V53A 2QQDA 3QTLD 3SEKC 2SGEI 1PJUA 1TURA 1H0ZA 2N71A 2P6AC 2GKTI 1OVOA 1AN1I 1OMTA 2KMPA 1PPFI 1SGPI 1LR7A 1TUSA
chains in the Genus database with same CATH superfamily
2M5XA 2Y0MA 5CCMA 2SGQI 1SGYI 2JW6A 5HQ8A 2ROWA 4HGUA 3UGLA 1V1IA 1W4RA 1DS3I 1SGDI 1X74A 3QWPA 1KMAA 2DB6A 2FNFX 2WVJA 3E2IA 2ENNA 1TGSI 3CXLA 2QQCA 2CWGA 1S20A 1LR9A 1W3SA 2A20A 2LEOA 1P9GA 4FKDA 2W0TA 3UEYA 1FY7A 5EX0A 2NU2I 3TOAA 1NUBA 1WGTA 2DIPA 1PTRA 1IY5A 4UXJA 3TJQA 1UUCA 1Z2IA 3R5AA 5FUYA 1R79A 2GKVA 3VDPA 1UVFA 2L8EA 2ARPF 2KMOA 2NU1I 2QQEA 1PCEA 1LR8A 3PDNA 1CT0I 3R5BA 1MT1A 2UZ3A 2NU3I 2SGDI 2YUUA 2JA1A 2UVOA 1TBQR 4UXIA 1HDLA 1TOTA 2KCXA 2OU2A 5FUXA 5FUWA 1FARA 2JXDA 1CGJI 1DS2I 2RC4A 1R0RI 2YQPA 4SGBI 3FSYA 3SGBI 3TO7A 2KMRA 2QQ0A 4OVOA 1ULMA 5E3RA 2PQ8A 1X4SA 2B8TA 2V1CC 1FYBA 3D00A 1Y1CA 2CJSC 3QAHA 1MJBA 1WTJA 2CWFA 1MJ9A 2SGFI 5E3QA 2L7XA 3TO6A 2J9RA 2GVIA 1RFHA 5J8FA 3GOXA 2XRCA 4DNCA 2N1AB 2JZMA 3VDUA 1TBRR 3FC3A 2E73A 3UEJA 1WKXA 3HH2C 1TIHA 4WP4A 3OXFA 4UXHA 2B0UC 2V1CA 3SGQI 2LB7A 5HI7A 3B4VC 1XX6A 3VE5A 1N13A 4E1RA 1Z7KB 2E5RA 3OVOA 2BUSA 7WGAA 2F3CI 1M8CA 1CSOI 1TBNA 9WGAA 1SGQI 1IY6A 2JYYA 1YU6C 2OD1A 2NU0I 4JCVE 2GIVA 1MJAA 4E1PA 5JHWC 2NU4I 1SGEI 5DAEA 1BUSA 1HEVA 4AMLA 1HPTA 1K7UA 1SGNI 2VRWB 3KY9A 1CT4I 1V1HA 2N52A 4L9MA 1CE3A 1HJAI 1IW4A 2N17A 4MPIA 3RU0A 1KBEA 3OL0A 1TBOA 2CWHA 1YTPA 1CT2I 2SGPI 1ULNA 2ERWA 3R5DA 2KMQA 4GI3C 1UVGA 2WGCA 2WCYA 2X52A 1M8BA 1NXUA 1Q9BA 1UHAA 2GKRI 2ENZA 1ULKA 2RIJA 4B6DA 1OMUA 5J8CA 2ORWA 1Y1BA 1CHOI 1BMOA 1OYVI 2J87A 2X3TA 3FSXA 2DKVA 1CGII 1PTQA 1SGRI 2OVOA 2V53A 1K7TA 2QQDA 1Y8FA 3QTLD 3SEKC 3UOEA 1XBTA 2SGEI 3TO9A 1KBFA 2QPOA 2OZUA 1PJUA 1TURA 1VDDA 1H0ZA 4A24A 2N71A 1FAQA 2P6AC 1P9ZA 2GKTI 2LUYA 2ORVA 3UFFA 3OXLA 3OXGA 3MEKA 3UGDA 2ELIA 1K7VA 1OVOA 2ODDA 5E3PA 5EX3A 3BJIA 3TOBA 1U5KA 1WGCA 1AN1I 5CCLA 1XA6A 1OMTA 3UGIA 2KMPA 1PPFI 3E59A 3R5CA 1SGPI 2K9HA 1LR7A 1TUSA 5FUVA
chains in the Genus database with same CATH topology
2M5XA 5CCMA 2SGQI 1SGYI 2JW6A 5HQ8A 2ROWA 4HGUA 3UGLA 1V1IA 1W4RA 1DS3I 1SGDI 1X74A 3QWPA 1KMAA 2DB6A 2FNFX 2WVJA 3E2IA 2ENNA 1TGSI 3CXLA 2QQCA 1LR9A 1W3SA 2A20A 2LEOA 4FKDA 2W0TA 3UEYA 5EX0A 2NU2I 1NUBA 2DIPA 1PTRA 1IY5A 4UXJA 3TJQA 1UUCA 5FUYA 1R79A 2GKVA 3VDPA 1UVFA 2L8EA 2ARPF 2KMOA 2NU1I 2QQEA 1PCEA 1LR8A 3PDNA 1CT0I 1MT1A 2UZ3A 2NU3I 2SGDI 2YUUA 2JA1A 4UXIA 1TBQR 1HDLA 1TOTA 2KCXA 5FUXA 5FUWA 1FARA 2JXDA 1CGJI 1DS2I 2YQPA 1R0RI 4SGBI 3SGBI 2KMRA 2QQ0A 4OVOA 1X4SA 2B8TA 2V1CC 1FYBA 3D00A 1Y1CA 2CJSC 2SGFI 2L7XA 2J9RA 2GVIA 1RFHA 3GOXA 2XRCA 2N1AB 2JZMA 3VDUA 1TBRR 3FC3A 2E73A 3UEJA 3HH2C 1TIHA 3OXFA 4UXHA 2B0UC 2V1CA 3SGQI 5HI7A 3B4VC 1XX6A 3VE5A 1N13A 4E1RA 1Z7KB 2E5RA 3OVOA 2BUSA 2F3CI 1M8CA 1CSOI 1TBNA 1IY6A 1SGQI 2JYYA 1YU6C 2OD1A 2NU0I 4JCVE 5JHWC 4E1PA 2NU4I 1SGEI 5DAEA 1BUSA 1HPTA 2VRWB 1SGNI 3KY9A 1CT4I 1V1HA 2N52A 4L9MA 1CE3A 1HJAI 1IW4A 2N17A 3RU0A 1KBEA 3OL0A 1TBOA 1YTPA 1CT2I 2SGPI 2ERWA 2KMQA 4GI3C 1UVGA 2WCYA 1M8BA 2GKRI 2ENZA 4B6DA 1OMUA 2ORWA 1Y1BA 1CHOI 1BMOA 1OYVI 2J87A 2OVOA 1CGII 1PTQA 1SGRI 2V53A 2QQDA 1Y8FA 3QTLD 3SEKC 1XBTA 2SGEI 1KBFA 2QPOA 1PJUA 1TURA 1VDDA 1H0ZA 4A24A 2N71A 1FAQA 2P6AC 2GKTI 2LUYA 2ORVA 3UFFA 3OXLA 3OXGA 3MEKA 3UGDA 2ELIA 1OVOA 2ODDA 5EX3A 3BJIA 1U5KA 1AN1I 5CCLA 1XA6A 1OMTA 3UGIA 2KMPA 1PPFI 3E59A 1SGPI 2K9HA 1LR7A 1TUSA 5FUVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2M5X A;  2SGQ I;  1SGY I;  4HGU A;  1DS3 I;  1SGD I;  1KMA A;  1TGS I;  2QQC A;  1LR9 A;  2LEO A;  2NU2 I;  1NUB A;  1IY5 A;  3TJQ A;  1UUC A;  2GKV A;  1UVF A;  2ARP F;  2KMO A;  2NU1 I;  1PCE A;  1LR8 A;  1CT0 I;  1MT1 A;  2NU3 I;  2SGD I;  1HDL A;  1TBQ R;  2KCX A;  2JXD A;  1CGJ I;  1DS2 I;  4SGB I;  1R0R I;  3SGB I;  2KMR A;  4OVO A;  1FYB A;  1Y1C A;  2SGF I;  2XRC A;  2JZM A;  1TBR R;  3HH2 C;  1TIH A;  3SGQ I;  2B0U C;  3B4V C;  1N13 A;  1Z7K B;  3OVO A;  2BUS A;  2F3C I;  1M8C A;  1CSO I;  1IY6 A;  1SGQ I;  2JYY A;  1YU6 C;  2NU0 I;  5JHW C;  2NU4 I;  1SGE I;  5DAE A;  1BUS A;  1HPT A;  1SGN I;  1CT4 I;  2N52 A;  1CE3 A;  1HJA I;  1IW4 A;  2N17 A;  1YTP A;  1CT2 I;  2SGP I;  2ERW A;  2KMQ A;  4GI3 C;  1UVG A;  2WCY A;  1M8B A;  2GKR I;  1OMU A;  1Y1B A;  1CHO I;  1BMO A;  1OYV I;  2OVO A;  1CGI I;  1SGR I;  2V53 A;  2QQD A;  3QTL D;  3SEK C;  2SGE I;  1PJU A;  1TUR A;  1H0Z A;  2N71 A;  2P6A C;  2GKT I;  1OVO A;  1AN1 I;  1OMT A;  2KMP A;  1PPF I;  1SGP I;  1LR7 A;  1TUS A; 
#chains in the Genus database with same CATH topology
 2M5X A;  2Y0M A;  5CCM A;  2SGQ I;  1SGY I;  2JW6 A;  5HQ8 A;  2ROW A;  4HGU A;  3UGL A;  1V1I A;  1W4R A;  1DS3 I;  1SGD I;  1X74 A;  3QWP A;  1KMA A;  2DB6 A;  2FNF X;  2WVJ A;  3E2I A;  2ENN A;  1TGS I;  3CXL A;  2QQC A;  2CWG A;  1S20 A;  1LR9 A;  1W3S A;  2A20 A;  2LEO A;  1P9G A;  4FKD A;  2W0T A;  3UEY A;  1FY7 A;  5EX0 A;  2NU2 I;  3TOA A;  1NUB A;  1WGT A;  2DIP A;  1PTR A;  1IY5 A;  4UXJ A;  3TJQ A;  1UUC A;  1Z2I A;  3R5A A;  5FUY A;  1R79 A;  2GKV A;  3VDP A;  1UVF A;  2L8E A;  2ARP F;  2KMO A;  2NU1 I;  2QQE A;  1PCE A;  1LR8 A;  3PDN A;  1CT0 I;  3R5B A;  1MT1 A;  2UZ3 A;  2NU3 I;  2SGD I;  2YUU A;  2JA1 A;  2UVO A;  1TBQ R;  4UXI A;  1HDL A;  1TOT A;  2KCX A;  2OU2 A;  5FUX A;  5FUW A;  1FAR A;  2JXD A;  1CGJ I;  1DS2 I;  2RC4 A;  1R0R I;  2YQP A;  4SGB I;  3FSY A;  3SGB I;  3TO7 A;  2KMR A;  2QQ0 A;  4OVO A;  1ULM A;  5E3R A;  2PQ8 A;  1X4S A;  2B8T A;  2V1C C;  1FYB A;  3D00 A;  1Y1C A;  2CJS C;  3QAH A;  1MJB A;  1WTJ A;  2CWF A;  1MJ9 A;  2SGF I;  5E3Q A;  2L7X A;  3TO6 A;  2J9R A;  2GVI A;  1RFH A;  5J8F A;  3GOX A;  2XRC A;  4DNC A;  2N1A B;  2JZM A;  3VDU A;  1TBR R;  3FC3 A;  2E73 A;  3UEJ A;  1WKX A;  3HH2 C;  1TIH A;  4WP4 A;  3OXF A;  4UXH A;  2B0U C;  2V1C A;  3SGQ I;  2LB7 A;  5HI7 A;  3B4V C;  1XX6 A;  3VE5 A;  1N13 A;  4E1R A;  1Z7K B;  2E5R A;  3OVO A;  2BUS A;  7WGA A;  2F3C I;  1M8C A;  1CSO I;  1TBN A;  9WGA A;  1SGQ I;  1IY6 A;  2JYY A;  1YU6 C;  2OD1 A;  2NU0 I;  4JCV E;  2GIV A;  1MJA A;  4E1P A;  5JHW C;  2NU4 I;  1SGE I;  5DAE A;  1BUS A;  1HEV A;  4AML A;  1HPT A;  1K7U A;  1SGN I;  2VRW B;  3KY9 A;  1CT4 I;  1V1H A;  2N52 A;  4L9M A;  1CE3 A;  1HJA I;  1IW4 A;  2N17 A;  4MPI A;  3RU0 A;  1KBE A;  3OL0 A;  1TBO A;  2CWH A;  1YTP A;  1CT2 I;  2SGP I;  1ULN A;  2ERW A;  3R5D A;  2KMQ A;  4GI3 C;  1UVG A;  2WGC A;  2WCY A;  2X52 A;  1M8B A;  1NXU A;  1Q9B A;  1UHA A;  2GKR I;  2ENZ A;  1ULK A;  2RIJ A;  4B6D A;  1OMU A;  5J8C A;  2ORW A;  1Y1B A;  1CHO I;  1BMO A;  1OYV I;  2J87 A;  2X3T A;  3FSX A;  2DKV A;  1CGI I;  1PTQ A;  1SGR I;  2OVO A;  2V53 A;  1K7T A;  2QQD A;  1Y8F A;  3QTL D;  3SEK C;  3UOE A;  1XBT A;  2SGE I;  3TO9 A;  1KBF A;  2QPO A;  2OZU A;  1PJU A;  1TUR A;  1VDD A;  1H0Z A;  4A24 A;  2N71 A;  1FAQ A;  2P6A C;  1P9Z A;  2GKT I;  2LUY A;  2ORV A;  3UFF A;  3OXL A;  3OXG A;  3MEK A;  3UGD A;  2ELI A;  1K7V A;  1OVO A;  2ODD A;  5E3P A;  5EX3 A;  3BJI A;  3TOB A;  1U5K A;  1WGC A;  1AN1 I;  5CCL A;  1XA6 A;  1OMT A;  3UGI A;  2KMP A;  1PPF I;  3E59 A;  3R5C A;  1SGP I;  2K9H A;  1LR7 A;  1TUS A;  5FUV A; 
#chains in the Genus database with same CATH homology
 2M5X A;  5CCM A;  2SGQ I;  1SGY I;  2JW6 A;  5HQ8 A;  2ROW A;  4HGU A;  3UGL A;  1V1I A;  1W4R A;  1DS3 I;  1SGD I;  1X74 A;  3QWP A;  1KMA A;  2DB6 A;  2FNF X;  2WVJ A;  3E2I A;  2ENN A;  1TGS I;  3CXL A;  2QQC A;  1LR9 A;  1W3S A;  2A20 A;  2LEO A;  4FKD A;  2W0T A;  3UEY A;  5EX0 A;  2NU2 I;  1NUB A;  2DIP A;  1PTR A;  1IY5 A;  4UXJ A;  3TJQ A;  1UUC A;  5FUY A;  1R79 A;  2GKV A;  3VDP A;  1UVF A;  2L8E A;  2ARP F;  2KMO A;  2NU1 I;  2QQE A;  1PCE A;  1LR8 A;  3PDN A;  1CT0 I;  1MT1 A;  2UZ3 A;  2NU3 I;  2SGD I;  2YUU A;  2JA1 A;  4UXI A;  1TBQ R;  1HDL A;  1TOT A;  2KCX A;  5FUX A;  5FUW A;  1FAR A;  2JXD A;  1CGJ I;  1DS2 I;  2YQP A;  1R0R I;  4SGB I;  3SGB I;  2KMR A;  2QQ0 A;  4OVO A;  1X4S A;  2B8T A;  2V1C C;  1FYB A;  3D00 A;  1Y1C A;  2CJS C;  2SGF I;  2L7X A;  2J9R A;  2GVI A;  1RFH A;  3GOX A;  2XRC A;  2N1A B;  2JZM A;  3VDU A;  1TBR R;  3FC3 A;  2E73 A;  3UEJ A;  3HH2 C;  1TIH A;  3OXF A;  4UXH A;  2B0U C;  2V1C A;  3SGQ I;  5HI7 A;  3B4V C;  1XX6 A;  3VE5 A;  1N13 A;  4E1R A;  1Z7K B;  2E5R A;  3OVO A;  2BUS A;  2F3C I;  1M8C A;  1CSO I;  1TBN A;  1IY6 A;  1SGQ I;  2JYY A;  1YU6 C;  2OD1 A;  2NU0 I;  4JCV E;  5JHW C;  4E1P A;  2NU4 I;  1SGE I;  5DAE A;  1BUS A;  1HPT A;  2VRW B;  1SGN I;  3KY9 A;  1CT4 I;  1V1H A;  2N52 A;  4L9M A;  1CE3 A;  1HJA I;  1IW4 A;  2N17 A;  3RU0 A;  1KBE A;  3OL0 A;  1TBO A;  1YTP A;  1CT2 I;  2SGP I;  2ERW A;  2KMQ A;  4GI3 C;  1UVG A;  2WCY A;  1M8B A;  2GKR I;  2ENZ A;  4B6D A;  1OMU A;  2ORW A;  1Y1B A;  1CHO I;  1BMO A;  1OYV I;  2J87 A;  2OVO A;  1CGI I;  1PTQ A;  1SGR I;  2V53 A;  2QQD A;  1Y8F A;  3QTL D;  3SEK C;  1XBT A;  2SGE I;  1KBF A;  2QPO A;  1PJU A;  1TUR A;  1VDD A;  1H0Z A;  4A24 A;  2N71 A;  1FAQ A;  2P6A C;  2GKT I;  2LUY A;  2ORV A;  3UFF A;  3OXL A;  3OXG A;  3MEK A;  3UGD A;  2ELI A;  1OVO A;  2ODD A;  5EX3 A;  3BJI A;  1U5K A;  1AN1 I;  5CCL A;  1XA6 A;  1OMT A;  3UGI A;  2KMP A;  1PPF I;  3E59 A;  1SGP I;  2K9H A;  1LR7 A;  1TUS A;  5FUV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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