1AN1I

Leech-derived tryptase inhibitor/trypsin complex
Total Genus 9
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
40
structure length
40
Chain Sequence
KVCACPKILKPVCGSDGRTYANSCIARCNGVSIKSEGSCP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system.
pubmed doi rcsb
molecule tags Complex (serine protease/inhibitor)
source organism Sus scrofa
molecule keywords TRYPSIN
total genus 9
structure length 40
sequence length 40
ec nomenclature
pdb deposition date 1997-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1an1I00
2N17A 1BUSA 1KMAA 1DS3I 3OVOA 2GKRI 1Z7KB 1LR8A 2N71A 1CSOI 1OMUA 2KMOA 2JZMA 3B4VC 2SGDI 1IY5A 3SEKC 1YU6C 1SGDI 1CT0I 1SGEI 2XRCA 1AN1I 1Y1BA 1TGSI 1LR7A 4GI3C 2JXDA 1R0RI 2NU1I 1FYBA 4HGUA 2SGEI 1CGII 1N13A 1OVOA 1PCEA 1TBQR 2JYYA 2QQDA 2KMRA 1SGNI 1HJAI 2N52A 1CE3A 1SGPI 1CT2I 1DS2I 2M5XA 1TURA 2NU3I 1CGJI 1LR9A 1YTPA 2NU2I 4OVOA 2KCXA 1IW4A 1H0ZA 1HDLA 1SGRI 1HPTA 2LEOA 2KMQA 3TJQA 2SGFI 3HH2C 2OVOA 2SGQI 5JHWC 2GKTI 1TBRR 2SGPI 1CHOI 3QTLD 1PJUA 2NU4I 3SGBI 1UVFA 3SGQI 1UUCA 2NU0I 2KMPA 1UVGA 2WCYA 2ERWA 1BMOA 1SGQI 1MT1A 2P6AC 1OMTA 1TUSA 1NUBA 2BUSA 2B0UC 4SGBI 1TIHA 2QQCA 2V53A 1Y1CA 1OYVI 2ARPF 1PPFI 5DAEA 2GKVA 2F3CI 1M8BA 1IY6A 1CT4I 1SGYI 1M8CA
chains in the Genus database with same CATH superfamily
4FKDA 2A20A 2N17A 1BUSA 1MJAA 1WGTA 4E1PA 1KMAA 1DS3I 2Y0MA 3GOXA 3R5DA 2OD1A 2DB6A 3OVOA 5J8FA 2J87A 4UXHA 2GKRI 5EX3A 1Z7KB 9WGAA 7WGAA 2CWFA 2RC4A 2WGCA 1XBTA 2V1CA 1LR8A 2N71A 4UXIA 1CSOI 1OMUA 1X4SA 2KMOA 3R5CA 2JW6A 2JZMA 2K9HA 3B4VC 5FUWA 2SGDI 1ULMA 1IY5A 3SEKC 1PTRA 1Z2IA 1YU6C 4MPIA 3CXLA 4B6DA 1SGDI 1VDDA 1CT0I 3UGDA 1ULKA 3OL0A 2UVOA 3R5AA 5HI7A 1SGEI 1Q9BA 1HEVA 1WGCA 2XRCA 3VDUA 3FC3A 1AN1I 2L8EA 1Y1BA 4WP4A 2DKVA 1TGSI 5CCMA 1LR7A 2ENNA 4GI3C 2JXDA 2OZUA 1R0RI 2NU1I 1FYBA 5FUYA 1KBEA 3MEKA 4HGUA 3VDPA 2SGEI 1CGII 2ORWA 3BJIA 3OXGA 3RU0A 1N13A 4L9MA 2FNFX 1OVOA 1PCEA 1TBQR 3TO7A 2JYYA 2QQDA 2KMRA 3KY9A 1MJ9A 1SGNI 1HJAI 2W0TA 2E5RA 1MJBA 1Y8FA 1V1IA 2N52A 1CE3A 1SGPI 2RIJA 1CT2I 5EX0A 1DS2I 2CWHA 2GIVA 1TURA 2M5XA 2QQEA 5E3RA 2NU3I 1CGJI 1LR9A 1YTPA 2NU2I 4OVOA 2KCXA 2YUUA 1FY7A 1FARA 3UFFA 1IW4A 1UHAA 2WVJA 3PDNA 5J8CA 1RFHA 2X52A 3FSYA 1FAQA 3R5BA 3UEYA 5FUVA 1H0ZA 2V1CC 1HDLA 1SGRI 3TOBA 2ENZA 2LB7A 2UZ3A 5CCLA 5HQ8A 1HPTA 2LEOA 2KMQA 3UGIA 3TJQA 4E1RA 3UOEA 2SGFI 3HH2C 3TOAA 2OVOA 3FSXA 2SGQI 5JHWC 2GKTI 1NXUA 1TBRR 2E73A 1WTJA 2SGPI 3TO6A 1CHOI 3QTLD 2B8TA 4DNCA 2CWGA 1PJUA 2NU4I 2L7XA 3QAHA 3SGBI 1UVFA 1TOTA 2QPOA 3SGQI 4AMLA 2N1AB 4A24A 1ULNA 1UUCA 1X74A 2NU0I 1PTQA 1TBOA 1XX6A 1UVGA 2KMPA 2WCYA 5E3QA 3TO9A 2ERWA 3VE5A 1V1HA 1BMOA 1SGQI 1W3SA 3OXLA 1MT1A 2P6AC 1OMTA 1TUSA 2ODDA 2ROWA 1K7TA 1P9ZA 1S20A 2GVIA 3D00A 5FUXA 1XA6A 1WKXA 2J9RA 2DIPA 1NUBA 4UXJA 1TBNA 2BUSA 1KBFA 2YQPA 2B0UC 3E59A 2JA1A 1TIHA 4SGBI 5E3PA 3UEJA 2QQCA 2V53A 1Y1CA 1OYVI 2ARPF 2QQ0A 1U5KA 2X3TA 2OU2A 1R79A 2PQ8A 1K7UA 1PPFI 5DAEA 3E2IA 2LUYA 2GKVA 2ORVA 1P9GA 1W4RA 2VRWB 3UGLA 2CJSC 2ELIA 1K7VA 2F3CI 3OXFA 1M8BA 1IY6A 1CT4I 1SGYI 4JCVE 3QWPA 1M8CA
chains in the Genus database with same CATH topology
4FKDA 2A20A 2N17A 1BUSA 4E1PA 1KMAA 1DS3I 3GOXA 2OD1A 2DB6A 3OVOA 2J87A 4UXHA 2GKRI 5EX3A 1Z7KB 1XBTA 2V1CA 1LR8A 2N71A 4UXIA 1CSOI 1OMUA 1X4SA 2KMOA 2JW6A 2JZMA 2K9HA 3B4VC 5FUWA 2SGDI 1IY5A 3SEKC 1PTRA 4B6DA 1YU6C 3CXLA 1SGDI 1VDDA 1CT0I 3UGDA 3OL0A 5HI7A 1SGEI 2XRCA 3VDUA 3FC3A 1AN1I 2L8EA 1Y1BA 1TGSI 5CCMA 1LR7A 2ENNA 4GI3C 2JXDA 1R0RI 2NU1I 1FYBA 5FUYA 1KBEA 3MEKA 4HGUA 3VDPA 2SGEI 1CGII 2ORWA 3BJIA 3OXGA 3RU0A 1N13A 4L9MA 2FNFX 1OVOA 1PCEA 1TBQR 2JYYA 2QQDA 2KMRA 3KY9A 1SGNI 1HJAI 2W0TA 2E5RA 1Y8FA 1V1IA 2N52A 1CE3A 1SGPI 1CT2I 5EX0A 1DS2I 2M5XA 1TURA 2QQEA 2NU3I 1CGJI 1LR9A 1YTPA 2NU2I 4OVOA 2KCXA 2YUUA 1FARA 3UFFA 1IW4A 2WVJA 3PDNA 1RFHA 1H0ZA 1FAQA 3UEYA 5FUVA 2V1CC 1HDLA 1SGRI 2ENZA 2UZ3A 5CCLA 5HQ8A 1HPTA 2LEOA 2KMQA 3UGIA 3TJQA 4E1RA 2SGFI 3HH2C 2OVOA 2SGQI 5JHWC 2GKTI 2E73A 1TBRR 2SGPI 1CHOI 3QTLD 2B8TA 1PJUA 2NU4I 2L7XA 3SGBI 1UVFA 1TOTA 2QPOA 3SGQI 2N1AB 4A24A 1UUCA 1X74A 2NU0I 1PTQA 1TBOA 1XX6A 1UVGA 2KMPA 2WCYA 3VE5A 2ERWA 1V1HA 1BMOA 1SGQI 1W3SA 3OXLA 1MT1A 2P6AC 1OMTA 1TUSA 2ODDA 2ROWA 3D00A 5FUXA 2GVIA 1XA6A 2J9RA 2DIPA 1NUBA 4UXJA 1TBNA 2BUSA 1KBFA 2YQPA 2B0UC 3E59A 2JA1A 1TIHA 4SGBI 3UEJA 2QQCA 2V53A 1Y1CA 1OYVI 2ARPF 2QQ0A 1U5KA 1R79A 1PPFI 5DAEA 3E2IA 2LUYA 2GKVA 2ORVA 1W4RA 2VRWB 3UGLA 2CJSC 2ELIA 2F3CI 3OXFA 1M8BA 1IY6A 1CT4I 1SGYI 4JCVE 3QWPA 1M8CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2N17 A;  1BUS A;  1KMA A;  1DS3 I;  3OVO A;  2GKR I;  1Z7K B;  1LR8 A;  2N71 A;  1CSO I;  1OMU A;  2KMO A;  2JZM A;  3B4V C;  2SGD I;  1IY5 A;  3SEK C;  1YU6 C;  1SGD I;  1CT0 I;  1SGE I;  2XRC A;  1AN1 I;  1Y1B A;  1TGS I;  1LR7 A;  4GI3 C;  2JXD A;  1R0R I;  2NU1 I;  1FYB A;  4HGU A;  2SGE I;  1CGI I;  1N13 A;  1OVO A;  1PCE A;  1TBQ R;  2JYY A;  2QQD A;  2KMR A;  1SGN I;  1HJA I;  2N52 A;  1CE3 A;  1SGP I;  1CT2 I;  1DS2 I;  2M5X A;  1TUR A;  2NU3 I;  1CGJ I;  1LR9 A;  1YTP A;  2NU2 I;  4OVO A;  2KCX A;  1IW4 A;  1H0Z A;  1HDL A;  1SGR I;  1HPT A;  2LEO A;  2KMQ A;  3TJQ A;  2SGF I;  3HH2 C;  2OVO A;  2SGQ I;  5JHW C;  2GKT I;  1TBR R;  2SGP I;  1CHO I;  3QTL D;  1PJU A;  2NU4 I;  3SGB I;  1UVF A;  3SGQ I;  1UUC A;  2NU0 I;  2KMP A;  1UVG A;  2WCY A;  2ERW A;  1BMO A;  1SGQ I;  1MT1 A;  2P6A C;  1OMT A;  1TUS A;  1NUB A;  2BUS A;  2B0U C;  4SGB I;  1TIH A;  2QQC A;  2V53 A;  1Y1C A;  1OYV I;  2ARP F;  1PPF I;  5DAE A;  2GKV A;  2F3C I;  1M8B A;  1IY6 A;  1CT4 I;  1SGY I;  1M8C A; 
#chains in the Genus database with same CATH topology
 4FKD A;  2A20 A;  2N17 A;  1BUS A;  1MJA A;  1WGT A;  4E1P A;  1KMA A;  1DS3 I;  2Y0M A;  3GOX A;  3R5D A;  2OD1 A;  2DB6 A;  3OVO A;  5J8F A;  2J87 A;  4UXH A;  2GKR I;  5EX3 A;  1Z7K B;  9WGA A;  7WGA A;  2CWF A;  2RC4 A;  2WGC A;  1XBT A;  2V1C A;  1LR8 A;  2N71 A;  4UXI A;  1CSO I;  1OMU A;  1X4S A;  2KMO A;  3R5C A;  2JW6 A;  2JZM A;  2K9H A;  3B4V C;  5FUW A;  2SGD I;  1ULM A;  1IY5 A;  3SEK C;  1PTR A;  1Z2I A;  1YU6 C;  4MPI A;  3CXL A;  4B6D A;  1SGD I;  1VDD A;  1CT0 I;  3UGD A;  1ULK A;  3OL0 A;  2UVO A;  3R5A A;  5HI7 A;  1SGE I;  1Q9B A;  1HEV A;  1WGC A;  2XRC A;  3VDU A;  3FC3 A;  1AN1 I;  2L8E A;  1Y1B A;  4WP4 A;  2DKV A;  1TGS I;  5CCM A;  1LR7 A;  2ENN A;  4GI3 C;  2JXD A;  2OZU A;  1R0R I;  2NU1 I;  1FYB A;  5FUY A;  1KBE A;  3MEK A;  4HGU A;  3VDP A;  2SGE I;  1CGI I;  2ORW A;  3BJI A;  3OXG A;  3RU0 A;  1N13 A;  4L9M A;  2FNF X;  1OVO A;  1PCE A;  1TBQ R;  3TO7 A;  2JYY A;  2QQD A;  2KMR A;  3KY9 A;  1MJ9 A;  1SGN I;  1HJA I;  2W0T A;  2E5R A;  1MJB A;  1Y8F A;  1V1I A;  2N52 A;  1CE3 A;  1SGP I;  2RIJ A;  1CT2 I;  5EX0 A;  1DS2 I;  2CWH A;  2GIV A;  1TUR A;  2M5X A;  2QQE A;  5E3R A;  2NU3 I;  1CGJ I;  1LR9 A;  1YTP A;  2NU2 I;  4OVO A;  2KCX A;  2YUU A;  1FY7 A;  1FAR A;  3UFF A;  1IW4 A;  1UHA A;  2WVJ A;  3PDN A;  5J8C A;  1RFH A;  2X52 A;  3FSY A;  1FAQ A;  3R5B A;  3UEY A;  5FUV A;  1H0Z A;  2V1C C;  1HDL A;  1SGR I;  3TOB A;  2ENZ A;  2LB7 A;  2UZ3 A;  5CCL A;  5HQ8 A;  1HPT A;  2LEO A;  2KMQ A;  3UGI A;  3TJQ A;  4E1R A;  3UOE A;  2SGF I;  3HH2 C;  3TOA A;  2OVO A;  3FSX A;  2SGQ I;  5JHW C;  2GKT I;  1NXU A;  1TBR R;  2E73 A;  1WTJ A;  2SGP I;  3TO6 A;  1CHO I;  3QTL D;  2B8T A;  4DNC A;  2CWG A;  1PJU A;  2NU4 I;  2L7X A;  3QAH A;  3SGB I;  1UVF A;  1TOT A;  2QPO A;  3SGQ I;  4AML A;  2N1A B;  4A24 A;  1ULN A;  1UUC A;  1X74 A;  2NU0 I;  1PTQ A;  1TBO A;  1XX6 A;  1UVG A;  2KMP A;  2WCY A;  5E3Q A;  3TO9 A;  2ERW A;  3VE5 A;  1V1H A;  1BMO A;  1SGQ I;  1W3S A;  3OXL A;  1MT1 A;  2P6A C;  1OMT A;  1TUS A;  2ODD A;  2ROW A;  1K7T A;  1P9Z A;  1S20 A;  2GVI A;  3D00 A;  5FUX A;  1XA6 A;  1WKX A;  2J9R A;  2DIP A;  1NUB A;  4UXJ A;  1TBN A;  2BUS A;  1KBF A;  2YQP A;  2B0U C;  3E59 A;  2JA1 A;  1TIH A;  4SGB I;  5E3P A;  3UEJ A;  2QQC A;  2V53 A;  1Y1C A;  1OYV I;  2ARP F;  2QQ0 A;  1U5K A;  2X3T A;  2OU2 A;  1R79 A;  2PQ8 A;  1K7U A;  1PPF I;  5DAE A;  3E2I A;  2LUY A;  2GKV A;  2ORV A;  1P9G A;  1W4R A;  2VRW B;  3UGL A;  2CJS C;  2ELI A;  1K7V A;  2F3C I;  3OXF A;  1M8B A;  1IY6 A;  1CT4 I;  1SGY I;  4JCV E;  3QWP A;  1M8C A; 
#chains in the Genus database with same CATH homology
 4FKD A;  2A20 A;  2N17 A;  1BUS A;  4E1P A;  1KMA A;  1DS3 I;  3GOX A;  2OD1 A;  2DB6 A;  3OVO A;  2J87 A;  4UXH A;  2GKR I;  5EX3 A;  1Z7K B;  1XBT A;  2V1C A;  1LR8 A;  2N71 A;  4UXI A;  1CSO I;  1OMU A;  1X4S A;  2KMO A;  2JW6 A;  2JZM A;  2K9H A;  3B4V C;  5FUW A;  2SGD I;  1IY5 A;  3SEK C;  1PTR A;  4B6D A;  1YU6 C;  3CXL A;  1SGD I;  1VDD A;  1CT0 I;  3UGD A;  3OL0 A;  5HI7 A;  1SGE I;  2XRC A;  3VDU A;  3FC3 A;  1AN1 I;  2L8E A;  1Y1B A;  1TGS I;  5CCM A;  1LR7 A;  2ENN A;  4GI3 C;  2JXD A;  1R0R I;  2NU1 I;  1FYB A;  5FUY A;  1KBE A;  3MEK A;  4HGU A;  3VDP A;  2SGE I;  1CGI I;  2ORW A;  3BJI A;  3OXG A;  3RU0 A;  1N13 A;  4L9M A;  2FNF X;  1OVO A;  1PCE A;  1TBQ R;  2JYY A;  2QQD A;  2KMR A;  3KY9 A;  1SGN I;  1HJA I;  2W0T A;  2E5R A;  1Y8F A;  1V1I A;  2N52 A;  1CE3 A;  1SGP I;  1CT2 I;  5EX0 A;  1DS2 I;  2M5X A;  1TUR A;  2QQE A;  2NU3 I;  1CGJ I;  1LR9 A;  1YTP A;  2NU2 I;  4OVO A;  2KCX A;  2YUU A;  1FAR A;  3UFF A;  1IW4 A;  2WVJ A;  3PDN A;  1RFH A;  1H0Z A;  1FAQ A;  3UEY A;  5FUV A;  2V1C C;  1HDL A;  1SGR I;  2ENZ A;  2UZ3 A;  5CCL A;  5HQ8 A;  1HPT A;  2LEO A;  2KMQ A;  3UGI A;  3TJQ A;  4E1R A;  2SGF I;  3HH2 C;  2OVO A;  2SGQ I;  5JHW C;  2GKT I;  2E73 A;  1TBR R;  2SGP I;  1CHO I;  3QTL D;  2B8T A;  1PJU A;  2NU4 I;  2L7X A;  3SGB I;  1UVF A;  1TOT A;  2QPO A;  3SGQ I;  2N1A B;  4A24 A;  1UUC A;  1X74 A;  2NU0 I;  1PTQ A;  1TBO A;  1XX6 A;  1UVG A;  2KMP A;  2WCY A;  3VE5 A;  2ERW A;  1V1H A;  1BMO A;  1SGQ I;  1W3S A;  3OXL A;  1MT1 A;  2P6A C;  1OMT A;  1TUS A;  2ODD A;  2ROW A;  3D00 A;  5FUX A;  2GVI A;  1XA6 A;  2J9R A;  2DIP A;  1NUB A;  4UXJ A;  1TBN A;  2BUS A;  1KBF A;  2YQP A;  2B0U C;  3E59 A;  2JA1 A;  1TIH A;  4SGB I;  3UEJ A;  2QQC A;  2V53 A;  1Y1C A;  1OYV I;  2ARP F;  2QQ0 A;  1U5K A;  1R79 A;  1PPF I;  5DAE A;  3E2I A;  2LUY A;  2GKV A;  2ORV A;  1W4R A;  2VRW B;  3UGL A;  2CJS C;  2ELI A;  2F3C I;  3OXF A;  1M8B A;  1IY6 A;  1CT4 I;  1SGY I;  4JCV E;  3QWP A;  1M8C A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...