1FARA

Raf-1 cysteine rich domain, nmr, minimized average structure
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
52
structure length
52
Chain Sequence
LTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site.
pubmed doi rcsb
molecule tags Serine/threonine protein kinase
source organism Homo sapiens
molecule keywords RAF-1
total genus 2
structure length 52
sequence length 52
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 1996-09-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00130 C1_1 Phorbol esters/diacylglycerol binding domain (C1 domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.20 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1farA00
2J9RA 2ROWA 2J87A 3UFFA 2ORVA 4UXHA 3BJIA 1KBEA 1RFHA 1PTQA 1TBOA 1FAQA 1XX6A 1XBTA 3CXLA 3KY9A 3UGLA 2QQ0A 1Y8FA 2ORWA 2GVIA 4UXJA 1XA6A 4B6DA 5FUYA 2DB6A 2E73A 3UGDA 2YUUA 2JA1A 2ELIA 2ENNA 3E2IA 4UXIA 2WVJA 3UGIA 1KBFA 2UZ3A 1W4RA 5FUVA 4FKDA 2VRWB 3UEYA 4L9MA 1TBNA 2FNFX 5FUWA 3UEJA 5FUXA 2QQEA 2ENZA 1FARA 1PTRA 2QPOA 1R79A 2B8TA
chains in the Genus database with same CATH superfamily
2N52A 2V1CA 2X3TA 1HJAI 2E5RA 1SGRI 2L7XA 1MJ9A 2DKVA 1FY7A 1RFHA 5E3RA 1ULNA 2ARPF 2CWFA 2KMRA 1N13A 2M5XA 3UOEA 2QQ0A 1TURA 1W3SA 1Y8FA 2GKVA 2NU4I 2GVIA 2ORWA 2OU2A 2SGDI 2WGCA 2K9HA 2N17A 1LR9A 2CWGA 5HI7A 2YUUA 3TOAA 1CT4I 3FC3A 1OMUA 4UXIA 5EX3A 2PQ8A 1WKXA 4SGBI 3QTLD 2SGEI 2NU2I 2N71A 2VRWB 5HQ8A 1CT2I 1WGCA 1TBNA 2FNFX 2JYYA 2OD1A 3R5AA 3OXFA 1K7UA 3VDUA 2N1AB 1P9GA 1WGTA 1YU6C 1FARA 2JXDA 4JCVE 3TO6A 2OZUA 3RU0A 1BMOA 1FYBA 3MEKA 1Q9BA 1DS3I 1HEVA 2J9RA 1MT1A 1OVOA 2WCYA 1IW4A 2JZMA 4UXHA 1PCEA 1KBEA 1ULKA 1Y1CA 2KCXA 1PPFI 2SGPI 3FSYA 3TO9A 2GIVA 3TOBA 4DNCA 5CCLA 3CXLA 3KY9A 1CT0I 2A20A 3R5CA 5J8FA 1H0ZA 1SGQI 2DIPA 1V1IA 2RC4A 2XRCA 3TJQA 4AMLA 7WGAA 1X74A 1MJBA 1PJUA 2ENNA 1K7TA 1AN1I 2UZ3A 1KBFA 2V53A 1BUSA 5JHWC 2RIJA 4L9MA 3SEKC 3OXLA 5FUWA 2LEOA 1SGNI 3E59A 1FAQA 1SGYI 1TIHA 1U5KA 5FUXA 3SGQI 4MPIA 1Y1BA 1Z7KB 1CGJI 2BUSA 2SGQI 3FSXA 3QWPA 1V1HA 2L8EA 2JW6A 3D00A 4WP4A 1UVFA 3OL0A 2UVOA 1VDDA 1R0RI 2CJSC 2J87A 2LUYA 1CGII 2OVOA 3BJIA 1TBOA 1PTQA 4HGUA 1CHOI 2KMQA 1X4SA 1UUCA 3QAHA 1SGPI 1TBQR 3B4VC 2X52A 2DB6A 1UHAA 2E73A 2KMPA 1IY6A 2KMOA 1M8CA 3TO7A 2WVJA 2CWHA 3PDNA 3UGIA 9WGAA 3VDPA 1YTPA 1M8BA 1WTJA 2P6AC 4E1PA 4FKDA 5E3PA 3OXGA 1MJAA 5DAEA 2B0UC 3UEJA 2QQEA 1OYVI 2ENZA 3SGBI 1TUSA 5E3QA 2LB7A 1ULMA 2ODDA 1PTRA 2QQDA 2QPOA 1R79A 3R5DA 2B8TA 2SGFI 2ROWA 2Y0MA 1S20A 2F3CI 3UFFA 1NUBA 2ORVA 1HPTA 1K7VA 1LR7A 1LR8A 2GKTI 5EX0A 1XX6A 1XBTA 1SGDI 3HH2C 3UGLA 2NU3I 1DS2I 2YQPA 4GI3C 4UXJA 1XA6A 2QQCA 4OVOA 1KMAA 1Z2IA 4B6DA 1TBRR 5FUYA 5J8CA 3UGDA 2JA1A 2ELIA 3E2IA 4A24A 2NU0I 1TOTA 3VE5A 1W4RA 2W0TA 5FUVA 3GOXA 1IY5A 1UVGA 3UEYA 1HDLA 3OVOA 1SGEI 2GKRI 1CE3A 2ERWA 1OMTA 1NXUA 2NU1I 4E1RA 5CCMA 1P9ZA 1CSOI 3R5BA 1TGSI 2V1CC
chains in the Genus database with same CATH topology
2N52A 2V1CA 1HJAI 2E5RA 1SGRI 2L7XA 1RFHA 2ARPF 2KMRA 1N13A 2M5XA 2QQ0A 1TURA 1W3SA 1Y8FA 2GKVA 2NU4I 2GVIA 2ORWA 2SGDI 3QWPA 2K9HA 2N17A 1LR9A 5HI7A 2YUUA 1CT4I 3FC3A 1OMUA 4UXIA 5EX3A 4SGBI 3QTLD 2SGEI 2NU2I 2N71A 2VRWB 5HQ8A 1CT2I 2JYYA 1TBNA 2FNFX 2OD1A 3OXFA 3VDUA 2N1AB 1YU6C 2JXDA 1FARA 4JCVE 1BMOA 1FYBA 3MEKA 1DS3I 2J9RA 1MT1A 1OVOA 2WCYA 1IW4A 2JZMA 4UXHA 1PCEA 1KBEA 2KCXA 1Y1CA 2SGPI 1PPFI 5CCLA 1FAQA 3CXLA 3KY9A 1CT0I 2A20A 1H0ZA 1SGQI 2DIPA 1V1IA 2XRCA 3TJQA 1X74A 1PJUA 2ENNA 1AN1I 2UZ3A 1KBFA 2V53A 1BUSA 5JHWC 4L9MA 3SEKC 3OXLA 5FUWA 2LEOA 1SGNI 3E59A 1SGYI 1TIHA 1U5KA 5FUXA 3SGQI 1Y1BA 1Z7KB 1CGJI 2BUSA 2SGQI 1V1HA 2L8EA 2JW6A 3D00A 1UVFA 3OL0A 1VDDA 1R0RI 2CJSC 2J87A 2LUYA 1CGII 2OVOA 3BJIA 1TBOA 1PTQA 4HGUA 1CHOI 2KMQA 1X4SA 1UUCA 1SGPI 1TBQR 3B4VC 2DB6A 2E73A 2KMPA 1IY6A 2KMOA 1M8CA 2WVJA 3PDNA 3UGIA 3VDPA 1YTPA 1M8BA 2P6AC 4E1PA 4FKDA 3OXGA 5DAEA 2B0UC 3UEJA 2QQEA 1OYVI 2ENZA 3SGBI 1TUSA 2ODDA 1PTRA 2QQDA 2QPOA 1R79A 2B8TA 2SGFI 2ROWA 2F3CI 3UFFA 1NUBA 2ORVA 1HPTA 1LR7A 2GKTI 5EX0A 1XX6A 1XBTA 1SGDI 3HH2C 3UGLA 2NU3I 1DS2I 2YQPA 4GI3C 4UXJA 1XA6A 2QQCA 4OVOA 1KMAA 4B6DA 1TBRR 5FUYA 3UGDA 2JA1A 2ELIA 3E2IA 4A24A 2NU0I 1TOTA 3VE5A 1W4RA 2W0TA 5FUVA 3GOXA 1IY5A 1UVGA 3UEYA 1HDLA 3OVOA 1SGEI 2GKRI 1CE3A 2ERWA 1OMTA 2NU1I 4E1RA 5CCMA 1LR8A 1CSOI 3RU0A 1TGSI 2V1CC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J9R A;  2ROW A;  2J87 A;  3UFF A;  2ORV A;  4UXH A;  3BJI A;  1KBE A;  1RFH A;  1PTQ A;  1TBO A;  1FAQ A;  1XX6 A;  1XBT A;  3CXL A;  3KY9 A;  3UGL A;  2QQ0 A;  1Y8F A;  2ORW A;  2GVI A;  4UXJ A;  1XA6 A;  4B6D A;  5FUY A;  2DB6 A;  2E73 A;  3UGD A;  2YUU A;  2JA1 A;  2ELI A;  2ENN A;  3E2I A;  4UXI A;  2WVJ A;  3UGI A;  1KBF A;  2UZ3 A;  1W4R A;  5FUV A;  4FKD A;  2VRW B;  3UEY A;  4L9M A;  1TBN A;  2FNF X;  5FUW A;  3UEJ A;  5FUX A;  2QQE A;  2ENZ A;  1FAR A;  1PTR A;  2QPO A;  1R79 A;  2B8T A; 
#chains in the Genus database with same CATH topology
 2N52 A;  2V1C A;  2X3T A;  1HJA I;  2E5R A;  1SGR I;  2L7X A;  1MJ9 A;  2DKV A;  1FY7 A;  1RFH A;  5E3R A;  1ULN A;  2ARP F;  2CWF A;  2KMR A;  1N13 A;  2M5X A;  3UOE A;  2QQ0 A;  1TUR A;  1W3S A;  1Y8F A;  2GKV A;  2NU4 I;  2GVI A;  2ORW A;  2OU2 A;  2SGD I;  2WGC A;  2K9H A;  2N17 A;  1LR9 A;  2CWG A;  5HI7 A;  2YUU A;  3TOA A;  1CT4 I;  3FC3 A;  1OMU A;  4UXI A;  5EX3 A;  2PQ8 A;  1WKX A;  4SGB I;  3QTL D;  2SGE I;  2NU2 I;  2N71 A;  2VRW B;  5HQ8 A;  1CT2 I;  1WGC A;  1TBN A;  2FNF X;  2JYY A;  2OD1 A;  3R5A A;  3OXF A;  1K7U A;  3VDU A;  2N1A B;  1P9G A;  1WGT A;  1YU6 C;  1FAR A;  2JXD A;  4JCV E;  3TO6 A;  2OZU A;  3RU0 A;  1BMO A;  1FYB A;  3MEK A;  1Q9B A;  1DS3 I;  1HEV A;  2J9R A;  1MT1 A;  1OVO A;  2WCY A;  1IW4 A;  2JZM A;  4UXH A;  1PCE A;  1KBE A;  1ULK A;  1Y1C A;  2KCX A;  1PPF I;  2SGP I;  3FSY A;  3TO9 A;  2GIV A;  3TOB A;  4DNC A;  5CCL A;  3CXL A;  3KY9 A;  1CT0 I;  2A20 A;  3R5C A;  5J8F A;  1H0Z A;  1SGQ I;  2DIP A;  1V1I A;  2RC4 A;  2XRC A;  3TJQ A;  4AML A;  7WGA A;  1X74 A;  1MJB A;  1PJU A;  2ENN A;  1K7T A;  1AN1 I;  2UZ3 A;  1KBF A;  2V53 A;  1BUS A;  5JHW C;  2RIJ A;  4L9M A;  3SEK C;  3OXL A;  5FUW A;  2LEO A;  1SGN I;  3E59 A;  1FAQ A;  1SGY I;  1TIH A;  1U5K A;  5FUX A;  3SGQ I;  4MPI A;  1Y1B A;  1Z7K B;  1CGJ I;  2BUS A;  2SGQ I;  3FSX A;  3QWP A;  1V1H A;  2L8E A;  2JW6 A;  3D00 A;  4WP4 A;  1UVF A;  3OL0 A;  2UVO A;  1VDD A;  1R0R I;  2CJS C;  2J87 A;  2LUY A;  1CGI I;  2OVO A;  3BJI A;  1TBO A;  1PTQ A;  4HGU A;  1CHO I;  2KMQ A;  1X4S A;  1UUC A;  3QAH A;  1SGP I;  1TBQ R;  3B4V C;  2X52 A;  2DB6 A;  1UHA A;  2E73 A;  2KMP A;  1IY6 A;  2KMO A;  1M8C A;  3TO7 A;  2WVJ A;  2CWH A;  3PDN A;  3UGI A;  9WGA A;  3VDP A;  1YTP A;  1M8B A;  1WTJ A;  2P6A C;  4E1P A;  4FKD A;  5E3P A;  3OXG A;  1MJA A;  5DAE A;  2B0U C;  3UEJ A;  2QQE A;  1OYV I;  2ENZ A;  3SGB I;  1TUS A;  5E3Q A;  2LB7 A;  1ULM A;  2ODD A;  1PTR A;  2QQD A;  2QPO A;  1R79 A;  3R5D A;  2B8T A;  2SGF I;  2ROW A;  2Y0M A;  1S20 A;  2F3C I;  3UFF A;  1NUB A;  2ORV A;  1HPT A;  1K7V A;  1LR7 A;  1LR8 A;  2GKT I;  5EX0 A;  1XX6 A;  1XBT A;  1SGD I;  3HH2 C;  3UGL A;  2NU3 I;  1DS2 I;  2YQP A;  4GI3 C;  4UXJ A;  1XA6 A;  2QQC A;  4OVO A;  1KMA A;  1Z2I A;  4B6D A;  1TBR R;  5FUY A;  5J8C A;  3UGD A;  2JA1 A;  2ELI A;  3E2I A;  4A24 A;  2NU0 I;  1TOT A;  3VE5 A;  1W4R A;  2W0T A;  5FUV A;  3GOX A;  1IY5 A;  1UVG A;  3UEY A;  1HDL A;  3OVO A;  1SGE I;  2GKR I;  1CE3 A;  2ERW A;  1OMT A;  1NXU A;  2NU1 I;  4E1R A;  5CCM A;  1P9Z A;  1CSO I;  3R5B A;  1TGS I;  2V1C C; 
#chains in the Genus database with same CATH homology
 2N52 A;  2V1C A;  1HJA I;  2E5R A;  1SGR I;  2L7X A;  1RFH A;  2ARP F;  2KMR A;  1N13 A;  2M5X A;  2QQ0 A;  1TUR A;  1W3S A;  1Y8F A;  2GKV A;  2NU4 I;  2GVI A;  2ORW A;  2SGD I;  3QWP A;  2K9H A;  2N17 A;  1LR9 A;  5HI7 A;  2YUU A;  1CT4 I;  3FC3 A;  1OMU A;  4UXI A;  5EX3 A;  4SGB I;  3QTL D;  2SGE I;  2NU2 I;  2N71 A;  2VRW B;  5HQ8 A;  1CT2 I;  2JYY A;  1TBN A;  2FNF X;  2OD1 A;  3OXF A;  3VDU A;  2N1A B;  1YU6 C;  2JXD A;  1FAR A;  4JCV E;  1BMO A;  1FYB A;  3MEK A;  1DS3 I;  2J9R A;  1MT1 A;  1OVO A;  2WCY A;  1IW4 A;  2JZM A;  4UXH A;  1PCE A;  1KBE A;  2KCX A;  1Y1C A;  2SGP I;  1PPF I;  5CCL A;  1FAQ A;  3CXL A;  3KY9 A;  1CT0 I;  2A20 A;  1H0Z A;  1SGQ I;  2DIP A;  1V1I A;  2XRC A;  3TJQ A;  1X74 A;  1PJU A;  2ENN A;  1AN1 I;  2UZ3 A;  1KBF A;  2V53 A;  1BUS A;  5JHW C;  4L9M A;  3SEK C;  3OXL A;  5FUW A;  2LEO A;  1SGN I;  3E59 A;  1SGY I;  1TIH A;  1U5K A;  5FUX A;  3SGQ I;  1Y1B A;  1Z7K B;  1CGJ I;  2BUS A;  2SGQ I;  1V1H A;  2L8E A;  2JW6 A;  3D00 A;  1UVF A;  3OL0 A;  1VDD A;  1R0R I;  2CJS C;  2J87 A;  2LUY A;  1CGI I;  2OVO A;  3BJI A;  1TBO A;  1PTQ A;  4HGU A;  1CHO I;  2KMQ A;  1X4S A;  1UUC A;  1SGP I;  1TBQ R;  3B4V C;  2DB6 A;  2E73 A;  2KMP A;  1IY6 A;  2KMO A;  1M8C A;  2WVJ A;  3PDN A;  3UGI A;  3VDP A;  1YTP A;  1M8B A;  2P6A C;  4E1P A;  4FKD A;  3OXG A;  5DAE A;  2B0U C;  3UEJ A;  2QQE A;  1OYV I;  2ENZ A;  3SGB I;  1TUS A;  2ODD A;  1PTR A;  2QQD A;  2QPO A;  1R79 A;  2B8T A;  2SGF I;  2ROW A;  2F3C I;  3UFF A;  1NUB A;  2ORV A;  1HPT A;  1LR7 A;  2GKT I;  5EX0 A;  1XX6 A;  1XBT A;  1SGD I;  3HH2 C;  3UGL A;  2NU3 I;  1DS2 I;  2YQP A;  4GI3 C;  4UXJ A;  1XA6 A;  2QQC A;  4OVO A;  1KMA A;  4B6D A;  1TBR R;  5FUY A;  3UGD A;  2JA1 A;  2ELI A;  3E2I A;  4A24 A;  2NU0 I;  1TOT A;  3VE5 A;  1W4R A;  2W0T A;  5FUV A;  3GOX A;  1IY5 A;  1UVG A;  3UEY A;  1HDL A;  3OVO A;  1SGE I;  2GKR I;  1CE3 A;  2ERW A;  1OMT A;  2NU1 I;  4E1R A;  5CCM A;  1LR8 A;  1CSO I;  3RU0 A;  1TGS I;  2V1C C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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