1HDLA

Lekti domain one
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
55
structure length
55
Chain Sequence
KNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFINKCATCKMILEKEAKSQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Homologous Proteins with Different Folds: The Three-Dimensional Structures of Domains 1 and 6 of the Multiple Kazal-Type Inhibitor Lekti
pubmed doi rcsb
molecule tags Putative serine proteinase inhibitor
source organism Homo sapiens
molecule keywords SERINE PROTEINASE INHIBITOR LEKTI
total genus 12
structure length 55
sequence length 55
ec nomenclature
pdb deposition date 2000-11-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1hdlA00
2ARPF 1SGNI 2GKVA 1CT0I 1TGSI 2NU4I 1LR9A 3B4VC 5JHWC 1UUCA 1M8CA 2KMQA 3SEKC 2GKTI 1SGYI 2N52A 2BUSA 2KMPA 1BMOA 1FYBA 1OVOA 2XRCA 2NU2I 3HH2C 1OMTA 3SGBI 2N71A 1OMUA 1CGJI 1YU6C 3QTLD 1DS3I 1M8BA 1CE3A 2SGFI 3OVOA 1Z7KB 2WCYA 2KCXA 2V53A 2SGPI 1AN1I 3SGQI 1HPTA 1IY5A 2QQDA 4HGUA 1CT4I 1TUSA 2NU3I 1HDLA 1DS2I 5DAEA 1Y1CA 2JYYA 1PJUA 2NU1I 1BUSA 2KMRA 2SGDI 1CT2I 1LR7A 1CSOI 2F3CI 1KMAA 1TBQR 1HJAI 1SGEI 1N13A 1NUBA 2KMOA 1UVFA 1SGQI 4GI3C 2JZMA 3TJQA 1PCEA 2OVOA 1OYVI 1SGPI 2LEOA 2SGQI 1IW4A 1YTPA 2P6AC 4SGBI 2NU0I 4OVOA 2ERWA 1LR8A 1PPFI 1TIHA 1TURA 2GKRI 2JXDA 2B0UC 1CHOI 1SGDI 2QQCA 1R0RI 1Y1BA 2SGEI 1TBRR 1IY6A 1CGII 1UVGA 2N17A 1SGRI 1H0ZA 2M5XA 1MT1A
chains in the Genus database with same CATH superfamily
1X4SA 2GIVA 2ENNA 2ARPF 2QPOA 1R79A 1FY7A 2FNFX 3UGDA 3FC3A 2ENZA 5EX0A 5CCLA 1SGNI 4UXHA 2GKVA 1CT0I 3CXLA 1TGSI 2NU4I 1LR9A 1W3SA 3B4VC 2Y0MA 5J8FA 5JHWC 1UUCA 3TO7A 1M8CA 1V1HA 2RIJA 2KMQA 3SEKC 4JCVE 3OXLA 2GKTI 1SGYI 2N52A 2BUSA 2KMPA 1BMOA 1FYBA 1OVOA 2XRCA 1MJ9A 2NU2I 2ORWA 3R5BA 3UGLA 1K7TA 2OD1A 1OMTA 3HH2C 3SGBI 3FSXA 2ROWA 4FKDA 4E1RA 1WTJA 1RFHA 2N71A 1OMUA 3UOEA 1U5KA 1CGJI 1YU6C 1UHAA 1DS3I 2WGCA 3QTLD 2ODDA 5HI7A 1M8BA 1TBOA 1ULKA 1XX6A 2SGFI 2CWFA 2JW6A 1W4RA 3OVOA 4UXJA 5FUWA 9WGAA 4L9MA 1FAQA 1Z2IA 2ELIA 2UZ3A 1S20A 1Z7KB 2DKVA 2KCXA 2OZUA 2V53A 2WCYA 2E5RA 2SGPI 1AN1I 3E59A 1PTQA 2YQPA 2J87A 3E2IA 3PDNA 3SGQI 1HPTA 2CJSC 1IY5A 1NXUA 1PTRA 2QQDA 4HGUA 2GVIA 1CT4I 1TUSA 3KY9A 2NU3I 4A24A 3VDUA 1DS2I 1P9ZA 2OU2A 1HDLA 5EX3A 5FUYA 2DB6A 1Y1CA 2JYYA 5DAEA 1PJUA 1XA6A 2NU1I 1BUSA 1Y8FA 2KMRA 2RC4A 1HEVA 2SGDI 3OL0A 1LR7A 1CT2I 3UEYA 1CSOI 1ULNA 2LUYA 1VDDA 2F3CI 1KMAA 2W0TA 1TBQR 1HJAI 1SGEI 2L8EA 2YUUA 3R5AA 5J8CA 1WKXA 1N13A 1NUBA 1P9GA 2CWGA 1ULMA 3TO6A 2QQEA 3TOBA 1Q9BA 1KBFA 1WGCA 1K7VA 2KMOA 1UVFA 1SGQI 3UEJA 2X3TA 4GI3C 2UVOA 2N1AB 5HQ8A 2CWHA 2JZMA 1WGTA 3BJIA 3FSYA 3TJQA 1PCEA 7WGAA 4E1PA 2DIPA 2OVOA 4AMLA 5E3QA 5FUXA 2LB7A 2V1CC 1OYVI 3UFFA 1SGPI 2LEOA 2SGQI 3R5CA 5FUVA 3VDPA 1IW4A 1YTPA 2P6AC 2QQ0A 2WVJA 2JA1A 3QWPA 4SGBI 3QAHA 4WP4A 2NU0I 4OVOA 2ERWA 1LR8A 4UXIA 1PPFI 2X52A 2J9RA 1TIHA 1X74A 3D00A 3RU0A 4DNCA 1TOTA 1TURA 3TO9A 2GKRI 2L7XA 2JXDA 3R5DA 3TOAA 2B8TA 2VRWB 5E3RA 2B0UC 1CHOI 1SGDI 2QQCA 3OXGA 1R0RI 1KBEA 4MPIA 5E3PA 5CCMA 3GOXA 2E73A 1Y1BA 1K7UA 2SGEI 1TBRR 1MJAA 2PQ8A 1XBTA 3MEKA 1IY6A 1CGII 2A20A 1TBNA 1UVGA 1CE3A 2N17A 1SGRI 3VE5A 3OXFA 1V1IA 1H0ZA 1MJBA 2K9HA 3UGIA 2M5XA 1MT1A 2ORVA 1FARA 4B6DA 2V1CA
chains in the Genus database with same CATH topology
1X4SA 2ENNA 2ARPF 2QPOA 1R79A 2FNFX 3UGDA 3FC3A 2ENZA 5EX0A 5CCLA 1SGNI 4UXHA 2GKVA 1CT0I 3CXLA 1TGSI 2NU4I 1LR9A 1W3SA 3B4VC 5JHWC 1UUCA 1M8CA 1V1HA 2KMQA 3SEKC 4JCVE 3OXLA 2GKTI 1SGYI 2N52A 2BUSA 2KMPA 1BMOA 1FYBA 1OVOA 2XRCA 2NU2I 2ORWA 3UGLA 3HH2C 2OD1A 1OMTA 3SGBI 2ROWA 4FKDA 4E1RA 2N71A 1RFHA 1OMUA 1U5KA 1CGJI 1YU6C 3QTLD 1DS3I 2ODDA 5HI7A 1M8BA 1TBOA 1XX6A 2SGFI 4UXJA 5FUWA 2JW6A 1W4RA 3OVOA 1CE3A 4L9MA 1FAQA 2ELIA 2UZ3A 1Z7KB 2WCYA 2KCXA 2V53A 2E5RA 2SGPI 1AN1I 3E59A 1PTQA 2YQPA 2J87A 3E2IA 3PDNA 3SGQI 1HPTA 2CJSC 1IY5A 1PTRA 2QQDA 4HGUA 2GVIA 1CT4I 1TUSA 3KY9A 2NU3I 4A24A 3VDUA 1DS2I 1HDLA 5EX3A 5FUYA 2DB6A 1Y1CA 2JYYA 5DAEA 1PJUA 1XA6A 2NU1I 1BUSA 1Y8FA 2KMRA 2SGDI 3OL0A 1CT2I 1LR7A 3UEYA 1CSOI 2LUYA 1VDDA 2F3CI 1KMAA 2W0TA 1TBQR 1HJAI 1SGEI 2L8EA 2YUUA 1N13A 1NUBA 1KBFA 2QQEA 2KMOA 1UVFA 1SGQI 3UEJA 4GI3C 2N1AB 5HQ8A 2JZMA 3TJQA 3BJIA 1PCEA 4E1PA 2DIPA 2OVOA 5FUXA 2V1CC 1OYVI 3UFFA 1SGPI 2LEOA 2SGQI 5FUVA 3VDPA 1IW4A 1YTPA 2P6AC 2QQ0A 2WVJA 2JA1A 3QWPA 4SGBI 2NU0I 4OVOA 2ERWA 1LR8A 4UXIA 1PPFI 2J9RA 1TIHA 1X74A 3D00A 3RU0A 1TOTA 1TURA 2GKRI 2L7XA 2JXDA 2B8TA 2VRWB 2B0UC 1CHOI 1SGDI 2QQCA 3OXGA 1R0RI 1KBEA 5CCMA 3GOXA 2E73A 1Y1BA 2SGEI 1TBRR 1XBTA 3MEKA 1IY6A 1CGII 2A20A 1TBNA 1UVGA 2N17A 1SGRI 3VE5A 3OXFA 1V1IA 1H0ZA 2K9HA 3UGIA 2M5XA 1MT1A 2ORVA 1FARA 4B6DA 2V1CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ARP F;  1SGN I;  2GKV A;  1CT0 I;  1TGS I;  2NU4 I;  1LR9 A;  3B4V C;  5JHW C;  1UUC A;  1M8C A;  2KMQ A;  3SEK C;  2GKT I;  1SGY I;  2N52 A;  2BUS A;  2KMP A;  1BMO A;  1FYB A;  1OVO A;  2XRC A;  2NU2 I;  3HH2 C;  1OMT A;  3SGB I;  2N71 A;  1OMU A;  1CGJ I;  1YU6 C;  3QTL D;  1DS3 I;  1M8B A;  1CE3 A;  2SGF I;  3OVO A;  1Z7K B;  2WCY A;  2KCX A;  2V53 A;  2SGP I;  1AN1 I;  3SGQ I;  1HPT A;  1IY5 A;  2QQD A;  4HGU A;  1CT4 I;  1TUS A;  2NU3 I;  1HDL A;  1DS2 I;  5DAE A;  1Y1C A;  2JYY A;  1PJU A;  2NU1 I;  1BUS A;  2KMR A;  2SGD I;  1CT2 I;  1LR7 A;  1CSO I;  2F3C I;  1KMA A;  1TBQ R;  1HJA I;  1SGE I;  1N13 A;  1NUB A;  2KMO A;  1UVF A;  1SGQ I;  4GI3 C;  2JZM A;  3TJQ A;  1PCE A;  2OVO A;  1OYV I;  1SGP I;  2LEO A;  2SGQ I;  1IW4 A;  1YTP A;  2P6A C;  4SGB I;  2NU0 I;  4OVO A;  2ERW A;  1LR8 A;  1PPF I;  1TIH A;  1TUR A;  2GKR I;  2JXD A;  2B0U C;  1CHO I;  1SGD I;  2QQC A;  1R0R I;  1Y1B A;  2SGE I;  1TBR R;  1IY6 A;  1CGI I;  1UVG A;  2N17 A;  1SGR I;  1H0Z A;  2M5X A;  1MT1 A; 
#chains in the Genus database with same CATH topology
 1X4S A;  2GIV A;  2ENN A;  2ARP F;  2QPO A;  1R79 A;  1FY7 A;  2FNF X;  3UGD A;  3FC3 A;  2ENZ A;  5EX0 A;  5CCL A;  1SGN I;  4UXH A;  2GKV A;  1CT0 I;  3CXL A;  1TGS I;  2NU4 I;  1LR9 A;  1W3S A;  3B4V C;  2Y0M A;  5J8F A;  5JHW C;  1UUC A;  3TO7 A;  1M8C A;  1V1H A;  2RIJ A;  2KMQ A;  3SEK C;  4JCV E;  3OXL A;  2GKT I;  1SGY I;  2N52 A;  2BUS A;  2KMP A;  1BMO A;  1FYB A;  1OVO A;  2XRC A;  1MJ9 A;  2NU2 I;  2ORW A;  3R5B A;  3UGL A;  1K7T A;  2OD1 A;  1OMT A;  3HH2 C;  3SGB I;  3FSX A;  2ROW A;  4FKD A;  4E1R A;  1WTJ A;  1RFH A;  2N71 A;  1OMU A;  3UOE A;  1U5K A;  1CGJ I;  1YU6 C;  1UHA A;  1DS3 I;  2WGC A;  3QTL D;  2ODD A;  5HI7 A;  1M8B A;  1TBO A;  1ULK A;  1XX6 A;  2SGF I;  2CWF A;  2JW6 A;  1W4R A;  3OVO A;  4UXJ A;  5FUW A;  9WGA A;  4L9M A;  1FAQ A;  1Z2I A;  2ELI A;  2UZ3 A;  1S20 A;  1Z7K B;  2DKV A;  2KCX A;  2OZU A;  2V53 A;  2WCY A;  2E5R A;  2SGP I;  1AN1 I;  3E59 A;  1PTQ A;  2YQP A;  2J87 A;  3E2I A;  3PDN A;  3SGQ I;  1HPT A;  2CJS C;  1IY5 A;  1NXU A;  1PTR A;  2QQD A;  4HGU A;  2GVI A;  1CT4 I;  1TUS A;  3KY9 A;  2NU3 I;  4A24 A;  3VDU A;  1DS2 I;  1P9Z A;  2OU2 A;  1HDL A;  5EX3 A;  5FUY A;  2DB6 A;  1Y1C A;  2JYY A;  5DAE A;  1PJU A;  1XA6 A;  2NU1 I;  1BUS A;  1Y8F A;  2KMR A;  2RC4 A;  1HEV A;  2SGD I;  3OL0 A;  1LR7 A;  1CT2 I;  3UEY A;  1CSO I;  1ULN A;  2LUY A;  1VDD A;  2F3C I;  1KMA A;  2W0T A;  1TBQ R;  1HJA I;  1SGE I;  2L8E A;  2YUU A;  3R5A A;  5J8C A;  1WKX A;  1N13 A;  1NUB A;  1P9G A;  2CWG A;  1ULM A;  3TO6 A;  2QQE A;  3TOB A;  1Q9B A;  1KBF A;  1WGC A;  1K7V A;  2KMO A;  1UVF A;  1SGQ I;  3UEJ A;  2X3T A;  4GI3 C;  2UVO A;  2N1A B;  5HQ8 A;  2CWH A;  2JZM A;  1WGT A;  3BJI A;  3FSY A;  3TJQ A;  1PCE A;  7WGA A;  4E1P A;  2DIP A;  2OVO A;  4AML A;  5E3Q A;  5FUX A;  2LB7 A;  2V1C C;  1OYV I;  3UFF A;  1SGP I;  2LEO A;  2SGQ I;  3R5C A;  5FUV A;  3VDP A;  1IW4 A;  1YTP A;  2P6A C;  2QQ0 A;  2WVJ A;  2JA1 A;  3QWP A;  4SGB I;  3QAH A;  4WP4 A;  2NU0 I;  4OVO A;  2ERW A;  1LR8 A;  4UXI A;  1PPF I;  2X52 A;  2J9R A;  1TIH A;  1X74 A;  3D00 A;  3RU0 A;  4DNC A;  1TOT A;  1TUR A;  3TO9 A;  2GKR I;  2L7X A;  2JXD A;  3R5D A;  3TOA A;  2B8T A;  2VRW B;  5E3R A;  2B0U C;  1CHO I;  1SGD I;  2QQC A;  3OXG A;  1R0R I;  1KBE A;  4MPI A;  5E3P A;  5CCM A;  3GOX A;  2E73 A;  1Y1B A;  1K7U A;  2SGE I;  1TBR R;  1MJA A;  2PQ8 A;  1XBT A;  3MEK A;  1IY6 A;  1CGI I;  2A20 A;  1TBN A;  1UVG A;  1CE3 A;  2N17 A;  1SGR I;  3VE5 A;  3OXF A;  1V1I A;  1H0Z A;  1MJB A;  2K9H A;  3UGI A;  2M5X A;  1MT1 A;  2ORV A;  1FAR A;  4B6D A;  2V1C A; 
#chains in the Genus database with same CATH homology
 1X4S A;  2ENN A;  2ARP F;  2QPO A;  1R79 A;  2FNF X;  3UGD A;  3FC3 A;  2ENZ A;  5EX0 A;  5CCL A;  1SGN I;  4UXH A;  2GKV A;  1CT0 I;  3CXL A;  1TGS I;  2NU4 I;  1LR9 A;  1W3S A;  3B4V C;  5JHW C;  1UUC A;  1M8C A;  1V1H A;  2KMQ A;  3SEK C;  4JCV E;  3OXL A;  2GKT I;  1SGY I;  2N52 A;  2BUS A;  2KMP A;  1BMO A;  1FYB A;  1OVO A;  2XRC A;  2NU2 I;  2ORW A;  3UGL A;  3HH2 C;  2OD1 A;  1OMT A;  3SGB I;  2ROW A;  4FKD A;  4E1R A;  2N71 A;  1RFH A;  1OMU A;  1U5K A;  1CGJ I;  1YU6 C;  3QTL D;  1DS3 I;  2ODD A;  5HI7 A;  1M8B A;  1TBO A;  1XX6 A;  2SGF I;  4UXJ A;  5FUW A;  2JW6 A;  1W4R A;  3OVO A;  1CE3 A;  4L9M A;  1FAQ A;  2ELI A;  2UZ3 A;  1Z7K B;  2WCY A;  2KCX A;  2V53 A;  2E5R A;  2SGP I;  1AN1 I;  3E59 A;  1PTQ A;  2YQP A;  2J87 A;  3E2I A;  3PDN A;  3SGQ I;  1HPT A;  2CJS C;  1IY5 A;  1PTR A;  2QQD A;  4HGU A;  2GVI A;  1CT4 I;  1TUS A;  3KY9 A;  2NU3 I;  4A24 A;  3VDU A;  1DS2 I;  1HDL A;  5EX3 A;  5FUY A;  2DB6 A;  1Y1C A;  2JYY A;  5DAE A;  1PJU A;  1XA6 A;  2NU1 I;  1BUS A;  1Y8F A;  2KMR A;  2SGD I;  3OL0 A;  1CT2 I;  1LR7 A;  3UEY A;  1CSO I;  2LUY A;  1VDD A;  2F3C I;  1KMA A;  2W0T A;  1TBQ R;  1HJA I;  1SGE I;  2L8E A;  2YUU A;  1N13 A;  1NUB A;  1KBF A;  2QQE A;  2KMO A;  1UVF A;  1SGQ I;  3UEJ A;  4GI3 C;  2N1A B;  5HQ8 A;  2JZM A;  3TJQ A;  3BJI A;  1PCE A;  4E1P A;  2DIP A;  2OVO A;  5FUX A;  2V1C C;  1OYV I;  3UFF A;  1SGP I;  2LEO A;  2SGQ I;  5FUV A;  3VDP A;  1IW4 A;  1YTP A;  2P6A C;  2QQ0 A;  2WVJ A;  2JA1 A;  3QWP A;  4SGB I;  2NU0 I;  4OVO A;  2ERW A;  1LR8 A;  4UXI A;  1PPF I;  2J9R A;  1TIH A;  1X74 A;  3D00 A;  3RU0 A;  1TOT A;  1TUR A;  2GKR I;  2L7X A;  2JXD A;  2B8T A;  2VRW B;  2B0U C;  1CHO I;  1SGD I;  2QQC A;  3OXG A;  1R0R I;  1KBE A;  5CCM A;  3GOX A;  2E73 A;  1Y1B A;  2SGE I;  1TBR R;  1XBT A;  3MEK A;  1IY6 A;  1CGI I;  2A20 A;  1TBN A;  1UVG A;  2N17 A;  1SGR I;  3VE5 A;  3OXF A;  1V1I A;  1H0Z A;  2K9H A;  3UGI A;  2M5X A;  1MT1 A;  2ORV A;  1FAR A;  4B6D A;  2V1C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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