1HPTA

Three-dimensional structure of a recombinant variant of human pancreatic secretory trypsin inhibitor (kazal type)
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
56
structure length
56
Chain Sequence
DSLGREAKCYNELNGCTYEYRPVCGTDGDTYPNECVLCFENRKRQTSILIQKSGPC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Three-dimensional structure of a recombinant variant of human pancreatic secretory trypsin inhibitor (Kazal type).
pubmed doi rcsb
molecule tags Serine protease inhibitor
source organism Homo sapiens
molecule keywords PANCREATIC SECRETORY TRYPSIN INHIBITOR (KAZAL TYPE) VARIANT
total genus 13
structure length 56
sequence length 56
ec nomenclature
pdb deposition date 1992-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1hptA00
2JXDA 1IW4A 5JHWC 1R0RI 4HGUA 1UUCA 2SGFI 2NU2I 2N17A 1LR8A 2KMQA 2SGQI 2GKTI 2LEOA 1CE3A 2JZMA 1HPTA 3SGQI 3B4VC 1Z7KB 1TBRR 2BUSA 1LR7A 2KMRA 1SGPI 1SGNI 1OVOA 2SGEI 1LR9A 2N71A 1SGDI 4GI3C 2M5XA 3TJQA 1DS3I 1TIHA 1IY6A 4SGBI 1DS2I 2QQDA 1HDLA 1PJUA 2WCYA 1OYVI 2N52A 1CHOI 2XRCA 1TGSI 2KMOA 1YTPA 1SGYI 1CT0I 1PCEA 1UVFA 3SGBI 2GKRI 1OMTA 1SGEI 2NU1I 1FYBA 1YU6C 3OVOA 1UVGA 2QQCA 1Y1CA 1NUBA 2KCXA 2F3CI 2JYYA 1TURA 1CGII 2ERWA 1IY5A 2SGDI 1KMAA 2P6AC 2SGPI 3SEKC 3HH2C 2KMPA 1OMUA 2V53A 1CT4I 2ARPF 2NU4I 1SGRI 2OVOA 1CGJI 1SGQI 1Y1BA 5DAEA 2B0UC 1PPFI 1BUSA 1N13A 2NU3I 1TUSA 1M8BA 1CT2I 3QTLD 1CSOI 1TBQR 1HJAI 1BMOA 2GKVA 1M8CA 1AN1I 4OVOA 2NU0I 1H0ZA 1MT1A
chains in the Genus database with same CATH superfamily
4FKDA 2JXDA 2CWGA 5EX0A 1IW4A 3GOXA 4E1RA 5J8CA 5JHWC 2E73A 2QPOA 1R0RI 2ORWA 1KBFA 2DIPA 4HGUA 1UUCA 2SGFI 2NU2I 2J87A 1LR8A 2N17A 3OXFA 4WP4A 5E3RA 1ULMA 2KMQA 2SGQI 2V1CA 2W0TA 1PTQA 1WTJA 2GKTI 2FNFX 2LEOA 1KBEA 1CE3A 1V1HA 1K7UA 1HPTA 1XX6A 2JZMA 2GVIA 3MEKA 5FUVA 3SGQI 3B4VC 1Z7KB 2ENNA 1TBRR 2QQ0A 3UOEA 2BUSA 1LR7A 2L7XA 1PTRA 3CXLA 2K9HA 2KMRA 5E3QA 1XBTA 1SGPI 1SGNI 2CWHA 3KY9A 1Z2IA 1OVOA 2SGEI 2CJSC 3E59A 1LR9A 1SGDI 1Y8FA 2N71A 3BJIA 2M5XA 4GI3C 3TJQA 1DS3I 1TIHA 1IY6A 4SGBI 2V1CC 2X3TA 3RU0A 1DS2I 1ULNA 2QQDA 1WGCA 2RC4A 4DNCA 3UFFA 3OXLA 3UGLA 4UXHA 2B8TA 2Y0MA 4MPIA 3VDUA 1HDLA 1X4SA 1PJUA 1W3SA 2WCYA 3R5BA 1OYVI 2N52A 1ULKA 1CHOI 2OD1A 2XRCA 5FUXA 1TGSI 2KMOA 2L8EA 1X74A 1MJ9A 1S20A 2LB7A 1FY7A 1SGYI 1CT0I 1YTPA 3TOBA 5HQ8A 1PCEA 1UHAA 4A24A 1UVFA 1RFHA 2LUYA 2GKRI 1OMTA 1SGEI 2NU1I 3SGBI 1FYBA 1R79A 1YU6C 2UVOA 2OZUA 3OVOA 1UVGA 3R5DA 2QQCA 1NXUA 1W4RA 1Y1CA 3R5AA 2GIVA 5E3PA 3UGDA 1VDDA 1NUBA 2KCXA 9WGAA 1K7TA 2F3CI 3TO6A 2JYYA 1TURA 3QWPA 2YQPA 2X52A 1CGII 2ERWA 3E2IA 2A20A 3VDPA 2ELIA 2PQ8A 1IY5A 2SGDI 1K7VA 5FUYA 1KMAA 2WVJA 5EX3A 3FC3A 5HI7A 3D00A 3TO9A 2E5RA 2P6AC 1U5KA 2SGPI 3SEKC 2YUUA 2JW6A 2UZ3A 2J9RA 3HH2C 5CCMA 3UGIA 2KMPA 1OMUA 1P9ZA 2V53A 3UEJA 2RIJA 1CT4I 3UEYA 2ARPF 3VE5A 2QQEA 1FAQA 2NU4I 3FSXA 3TOAA 3OXGA 1SGRI 2OVOA 4UXJA 1MJBA 1CGJI 1SGQI 4L9MA 1TOTA 2CWFA 4AMLA 1Y1BA 1Q9BA 2ROWA 2VRWB 5DAEA 2B0UC 2DKVA 5CCLA 1PPFI 1WKXA 1XA6A 7WGAA 1BUSA 5J8FA 1N13A 2NU3I 2ODDA 1TUSA 4B6DA 3OL0A 1M8BA 1CT2I 3QTLD 1HEVA 1CSOI 1FARA 1MJAA 1P9GA 1TBQR 1HJAI 1TBOA 2OU2A 3PDNA 4UXIA 5FUWA 3FSYA 1BMOA 2GKVA 2JA1A 1M8CA 1AN1I 1V1IA 2DB6A 2ORVA 2NU0I 4OVOA 4E1PA 1H0ZA 1MT1A 2ENZA 2N1AB 3QAHA 3TO7A 1WGTA 1TBNA 2WGCA 4JCVE 3R5CA
chains in the Genus database with same CATH topology
4FKDA 2JXDA 5EX0A 1IW4A 3GOXA 4E1RA 5JHWC 2E73A 2QPOA 1R0RI 2ORWA 1KBFA 2DIPA 4HGUA 1UUCA 2SGFI 2NU2I 2J87A 1LR8A 2N17A 3OXFA 2KMQA 2V1CA 2SGQI 2W0TA 1PTQA 2GKTI 2LEOA 2FNFX 1KBEA 1CE3A 1V1HA 1HPTA 1XX6A 2JZMA 2GVIA 3MEKA 5FUVA 3SGQI 3B4VC 1Z7KB 2ENNA 1TBRR 2QQ0A 2BUSA 1LR7A 2L7XA 1PTRA 3CXLA 2K9HA 2KMRA 1XBTA 1SGPI 1SGNI 3KY9A 3E59A 1OVOA 2SGEI 2CJSC 1LR9A 1SGDI 1Y8FA 2N71A 3BJIA 2M5XA 4GI3C 3TJQA 1DS3I 1TIHA 1IY6A 4SGBI 2V1CC 3RU0A 1DS2I 2QQDA 3UFFA 3OXLA 3UGLA 4UXHA 2B8TA 3VDUA 1HDLA 1X4SA 1PJUA 1W3SA 2WCYA 1OYVI 2N52A 1CHOI 2OD1A 2XRCA 5FUXA 1TGSI 2KMOA 2L8EA 1X74A 1YTPA 1SGYI 1CT0I 5HQ8A 1PCEA 4A24A 1UVFA 1RFHA 2LUYA 2GKRI 1OMTA 1SGEI 2NU1I 3SGBI 1FYBA 1R79A 1YU6C 3OVOA 1UVGA 2QQCA 1W4RA 1Y1CA 3UGDA 1VDDA 1NUBA 2KCXA 2F3CI 2JYYA 1TURA 3QWPA 2YQPA 1CGII 2ERWA 3E2IA 2A20A 3VDPA 2ELIA 1IY5A 2SGDI 5FUYA 1KMAA 2WVJA 5EX3A 3FC3A 5HI7A 3D00A 2E5RA 2P6AC 1U5KA 2SGPI 3SEKC 2YUUA 2JW6A 2UZ3A 2J9RA 3HH2C 5CCMA 3UGIA 2KMPA 1OMUA 2V53A 3UEJA 3VE5A 1CT4I 3UEYA 2ARPF 1FAQA 2QQEA 2NU4I 3OXGA 1SGRI 2OVOA 4UXJA 1CGJI 1SGQI 4L9MA 1TOTA 1Y1BA 2ROWA 2VRWB 5DAEA 2B0UC 5CCLA 1PPFI 1XA6A 1BUSA 1N13A 2NU3I 2ODDA 1TUSA 4B6DA 3OL0A 1M8BA 1CT2I 3QTLD 1CSOI 1FARA 1TBQR 1TBOA 3PDNA 1HJAI 4UXIA 5FUWA 1BMOA 2GKVA 2JA1A 1M8CA 1AN1I 1V1IA 2DB6A 2ORVA 2NU0I 4OVOA 4E1PA 1H0ZA 1MT1A 2ENZA 2N1AB 1TBNA 4JCVE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JXD A;  1IW4 A;  5JHW C;  1R0R I;  4HGU A;  1UUC A;  2SGF I;  2NU2 I;  2N17 A;  1LR8 A;  2KMQ A;  2SGQ I;  2GKT I;  2LEO A;  1CE3 A;  2JZM A;  1HPT A;  3SGQ I;  3B4V C;  1Z7K B;  1TBR R;  2BUS A;  1LR7 A;  2KMR A;  1SGP I;  1SGN I;  1OVO A;  2SGE I;  1LR9 A;  2N71 A;  1SGD I;  4GI3 C;  2M5X A;  3TJQ A;  1DS3 I;  1TIH A;  1IY6 A;  4SGB I;  1DS2 I;  2QQD A;  1HDL A;  1PJU A;  2WCY A;  1OYV I;  2N52 A;  1CHO I;  2XRC A;  1TGS I;  2KMO A;  1YTP A;  1SGY I;  1CT0 I;  1PCE A;  1UVF A;  3SGB I;  2GKR I;  1OMT A;  1SGE I;  2NU1 I;  1FYB A;  1YU6 C;  3OVO A;  1UVG A;  2QQC A;  1Y1C A;  1NUB A;  2KCX A;  2F3C I;  2JYY A;  1TUR A;  1CGI I;  2ERW A;  1IY5 A;  2SGD I;  1KMA A;  2P6A C;  2SGP I;  3SEK C;  3HH2 C;  2KMP A;  1OMU A;  2V53 A;  1CT4 I;  2ARP F;  2NU4 I;  1SGR I;  2OVO A;  1CGJ I;  1SGQ I;  1Y1B A;  5DAE A;  2B0U C;  1PPF I;  1BUS A;  1N13 A;  2NU3 I;  1TUS A;  1M8B A;  1CT2 I;  3QTL D;  1CSO I;  1TBQ R;  1HJA I;  1BMO A;  2GKV A;  1M8C A;  1AN1 I;  4OVO A;  2NU0 I;  1H0Z A;  1MT1 A; 
#chains in the Genus database with same CATH topology
 4FKD A;  2JXD A;  2CWG A;  5EX0 A;  1IW4 A;  3GOX A;  4E1R A;  5J8C A;  5JHW C;  2E73 A;  2QPO A;  1R0R I;  2ORW A;  1KBF A;  2DIP A;  4HGU A;  1UUC A;  2SGF I;  2NU2 I;  2J87 A;  1LR8 A;  2N17 A;  3OXF A;  4WP4 A;  5E3R A;  1ULM A;  2KMQ A;  2SGQ I;  2V1C A;  2W0T A;  1PTQ A;  1WTJ A;  2GKT I;  2FNF X;  2LEO A;  1KBE A;  1CE3 A;  1V1H A;  1K7U A;  1HPT A;  1XX6 A;  2JZM A;  2GVI A;  3MEK A;  5FUV A;  3SGQ I;  3B4V C;  1Z7K B;  2ENN A;  1TBR R;  2QQ0 A;  3UOE A;  2BUS A;  1LR7 A;  2L7X A;  1PTR A;  3CXL A;  2K9H A;  2KMR A;  5E3Q A;  1XBT A;  1SGP I;  1SGN I;  2CWH A;  3KY9 A;  1Z2I A;  1OVO A;  2SGE I;  2CJS C;  3E59 A;  1LR9 A;  1SGD I;  1Y8F A;  2N71 A;  3BJI A;  2M5X A;  4GI3 C;  3TJQ A;  1DS3 I;  1TIH A;  1IY6 A;  4SGB I;  2V1C C;  2X3T A;  3RU0 A;  1DS2 I;  1ULN A;  2QQD A;  1WGC A;  2RC4 A;  4DNC A;  3UFF A;  3OXL A;  3UGL A;  4UXH A;  2B8T A;  2Y0M A;  4MPI A;  3VDU A;  1HDL A;  1X4S A;  1PJU A;  1W3S A;  2WCY A;  3R5B A;  1OYV I;  2N52 A;  1ULK A;  1CHO I;  2OD1 A;  2XRC A;  5FUX A;  1TGS I;  2KMO A;  2L8E A;  1X74 A;  1MJ9 A;  1S20 A;  2LB7 A;  1FY7 A;  1SGY I;  1CT0 I;  1YTP A;  3TOB A;  5HQ8 A;  1PCE A;  1UHA A;  4A24 A;  1UVF A;  1RFH A;  2LUY A;  2GKR I;  1OMT A;  1SGE I;  2NU1 I;  3SGB I;  1FYB A;  1R79 A;  1YU6 C;  2UVO A;  2OZU A;  3OVO A;  1UVG A;  3R5D A;  2QQC A;  1NXU A;  1W4R A;  1Y1C A;  3R5A A;  2GIV A;  5E3P A;  3UGD A;  1VDD A;  1NUB A;  2KCX A;  9WGA A;  1K7T A;  2F3C I;  3TO6 A;  2JYY A;  1TUR A;  3QWP A;  2YQP A;  2X52 A;  1CGI I;  2ERW A;  3E2I A;  2A20 A;  3VDP A;  2ELI A;  2PQ8 A;  1IY5 A;  2SGD I;  1K7V A;  5FUY A;  1KMA A;  2WVJ A;  5EX3 A;  3FC3 A;  5HI7 A;  3D00 A;  3TO9 A;  2E5R A;  2P6A C;  1U5K A;  2SGP I;  3SEK C;  2YUU A;  2JW6 A;  2UZ3 A;  2J9R A;  3HH2 C;  5CCM A;  3UGI A;  2KMP A;  1OMU A;  1P9Z A;  2V53 A;  3UEJ A;  2RIJ A;  1CT4 I;  3UEY A;  2ARP F;  3VE5 A;  2QQE A;  1FAQ A;  2NU4 I;  3FSX A;  3TOA A;  3OXG A;  1SGR I;  2OVO A;  4UXJ A;  1MJB A;  1CGJ I;  1SGQ I;  4L9M A;  1TOT A;  2CWF A;  4AML A;  1Y1B A;  1Q9B A;  2ROW A;  2VRW B;  5DAE A;  2B0U C;  2DKV A;  5CCL A;  1PPF I;  1WKX A;  1XA6 A;  7WGA A;  1BUS A;  5J8F A;  1N13 A;  2NU3 I;  2ODD A;  1TUS A;  4B6D A;  3OL0 A;  1M8B A;  1CT2 I;  3QTL D;  1HEV A;  1CSO I;  1FAR A;  1MJA A;  1P9G A;  1TBQ R;  1HJA I;  1TBO A;  2OU2 A;  3PDN A;  4UXI A;  5FUW A;  3FSY A;  1BMO A;  2GKV A;  2JA1 A;  1M8C A;  1AN1 I;  1V1I A;  2DB6 A;  2ORV A;  2NU0 I;  4OVO A;  4E1P A;  1H0Z A;  1MT1 A;  2ENZ A;  2N1A B;  3QAH A;  3TO7 A;  1WGT A;  1TBN A;  2WGC A;  4JCV E;  3R5C A; 
#chains in the Genus database with same CATH homology
 4FKD A;  2JXD A;  5EX0 A;  1IW4 A;  3GOX A;  4E1R A;  5JHW C;  2E73 A;  2QPO A;  1R0R I;  2ORW A;  1KBF A;  2DIP A;  4HGU A;  1UUC A;  2SGF I;  2NU2 I;  2J87 A;  1LR8 A;  2N17 A;  3OXF A;  2KMQ A;  2V1C A;  2SGQ I;  2W0T A;  1PTQ A;  2GKT I;  2LEO A;  2FNF X;  1KBE A;  1CE3 A;  1V1H A;  1HPT A;  1XX6 A;  2JZM A;  2GVI A;  3MEK A;  5FUV A;  3SGQ I;  3B4V C;  1Z7K B;  2ENN A;  1TBR R;  2QQ0 A;  2BUS A;  1LR7 A;  2L7X A;  1PTR A;  3CXL A;  2K9H A;  2KMR A;  1XBT A;  1SGP I;  1SGN I;  3KY9 A;  3E59 A;  1OVO A;  2SGE I;  2CJS C;  1LR9 A;  1SGD I;  1Y8F A;  2N71 A;  3BJI A;  2M5X A;  4GI3 C;  3TJQ A;  1DS3 I;  1TIH A;  1IY6 A;  4SGB I;  2V1C C;  3RU0 A;  1DS2 I;  2QQD A;  3UFF A;  3OXL A;  3UGL A;  4UXH A;  2B8T A;  3VDU A;  1HDL A;  1X4S A;  1PJU A;  1W3S A;  2WCY A;  1OYV I;  2N52 A;  1CHO I;  2OD1 A;  2XRC A;  5FUX A;  1TGS I;  2KMO A;  2L8E A;  1X74 A;  1YTP A;  1SGY I;  1CT0 I;  5HQ8 A;  1PCE A;  4A24 A;  1UVF A;  1RFH A;  2LUY A;  2GKR I;  1OMT A;  1SGE I;  2NU1 I;  3SGB I;  1FYB A;  1R79 A;  1YU6 C;  3OVO A;  1UVG A;  2QQC A;  1W4R A;  1Y1C A;  3UGD A;  1VDD A;  1NUB A;  2KCX A;  2F3C I;  2JYY A;  1TUR A;  3QWP A;  2YQP A;  1CGI I;  2ERW A;  3E2I A;  2A20 A;  3VDP A;  2ELI A;  1IY5 A;  2SGD I;  5FUY A;  1KMA A;  2WVJ A;  5EX3 A;  3FC3 A;  5HI7 A;  3D00 A;  2E5R A;  2P6A C;  1U5K A;  2SGP I;  3SEK C;  2YUU A;  2JW6 A;  2UZ3 A;  2J9R A;  3HH2 C;  5CCM A;  3UGI A;  2KMP A;  1OMU A;  2V53 A;  3UEJ A;  3VE5 A;  1CT4 I;  3UEY A;  2ARP F;  1FAQ A;  2QQE A;  2NU4 I;  3OXG A;  1SGR I;  2OVO A;  4UXJ A;  1CGJ I;  1SGQ I;  4L9M A;  1TOT A;  1Y1B A;  2ROW A;  2VRW B;  5DAE A;  2B0U C;  5CCL A;  1PPF I;  1XA6 A;  1BUS A;  1N13 A;  2NU3 I;  2ODD A;  1TUS A;  4B6D A;  3OL0 A;  1M8B A;  1CT2 I;  3QTL D;  1CSO I;  1FAR A;  1TBQ R;  1TBO A;  3PDN A;  1HJA I;  4UXI A;  5FUW A;  1BMO A;  2GKV A;  2JA1 A;  1M8C A;  1AN1 I;  1V1I A;  2DB6 A;  2ORV A;  2NU0 I;  4OVO A;  4E1P A;  1H0Z A;  1MT1 A;  2ENZ A;  2N1A B;  1TBN A;  4JCV E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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