1IW4A

Solution structure of ascidian trypsin inhibitor
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
55
structure length
55
Chain Sequence
AHMDCTEFNPLCRCNKMLGDLICAVIGDAKEEHRNMCALCCEHPGGFEYSNGPCE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of ascidian trypsin inhibitor determined by nuclear magnetic resonance spectroscopy.
pubmed doi rcsb
molecule tags Protein binding
molecule keywords trypsin inhibitor
total genus 8
structure length 55
sequence length 55
ec nomenclature
pdb deposition date 2002-04-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1iw4A00
1LR7A 3SEKC 3QTLD 1SGDI 3TJQA 1Y1CA 4GI3C 1N13A 1SGNI 1NUBA 2N52A 1CSOI 1CGJI 1AN1I 2QQDA 3SGBI 1HDLA 2F3CI 1PCEA 1SGEI 1UUCA 1HPTA 1UVGA 2NU3I 1CE3A 2XRCA 2NU1I 3B4VC 1MT1A 1IY5A 1Z7KB 2N17A 2SGEI 4HGUA 2SGDI 2NU4I 1BUSA 2NU2I 1LR8A 2GKTI 1SGPI 1TBRR 1TGSI 2N71A 1YU6C 2SGQI 1PJUA 3SGQI 2OVOA 1SGYI 2KCXA 1OMTA 2KMRA 2NU0I 1TIHA 1R0RI 1PPFI 2JZMA 1IY6A 1TBQR 1BMOA 1CT4I 1M8BA 1IW4A 1YTPA 1DS2I 1H0ZA 2LEOA 1SGQI 2JYYA 2JXDA 3HH2C 2M5XA 2V53A 2WCYA 1KMAA 2BUSA 2KMQA 4SGBI 2KMPA 2P6AC 1CGII 2ARPF 1TURA 1M8CA 4OVOA 3OVOA 2SGFI 1DS3I 1CT2I 1OVOA 2SGPI 2ERWA 1FYBA 1CHOI 5DAEA 1OYVI 2GKRI 1CT0I 2QQCA 1SGRI 2KMOA 1HJAI 1Y1BA 2B0UC 1OMUA 1UVFA 1LR9A 1TUSA 2GKVA 5JHWC
chains in the Genus database with same CATH superfamily
1WTJA 3R5CA 3PDNA 1LR7A 5FUWA 3SEKC 3QTLD 2N1AB 1SGDI 3TJQA 3E2IA 1Y1CA 4GI3C 1N13A 1TBNA 4L9MA 2DIPA 1SGNI 3FC3A 1NUBA 2V1CA 2YQPA 1Y8FA 2N52A 1CSOI 2JW6A 1Z2IA 1CGJI 3TO7A 1X74A 2W0TA 3TOBA 4DNCA 1AN1I 3QAHA 4E1PA 2QQDA 1PTRA 1P9ZA 3VDPA 1FARA 1S20A 2YUUA 3MEKA 3SGBI 1HDLA 2ORWA 2F3CI 1PCEA 1UHAA 1SGEI 1W4RA 5E3QA 4UXIA 1UUCA 1HPTA 1UVGA 2PQ8A 2E5RA 2NU3I 2FNFX 2J87A 1CE3A 2XRCA 1NXUA 2NU1I 3B4VC 1KBFA 1MT1A 2X52A 1IY5A 1Z7KB 3R5DA 1R79A 1MJ9A 2N17A 2SGEI 4HGUA 2JA1A 3GOXA 2SGDI 2NU4I 1BUSA 4MPIA 2NU2I 2ENNA 1MJAA 3FSXA 7WGAA 3UOEA 2QPOA 4JCVE 2LUYA 3OXFA 1FAQA 1LR8A 2GKTI 1SGPI 1TBRR 1TGSI 5EX0A 3E59A 3UGDA 2N71A 2OU2A 2OZUA 2X3TA 5CCLA 1TBOA 3OL0A 1YU6C 2SGQI 1K7UA 1X4SA 2RIJA 1WKXA 2ORVA 1PJUA 3SGQI 4A24A 1W3SA 1XA6A 2OVOA 3OXLA 5E3RA 1SGYI 3UEJA 1OMTA 2KCXA 5HI7A 1TIHA 1Q9BA 1MJBA 1WGTA 2KMRA 2NU0I 1R0RI 5FUYA 3TO6A 3FSYA 1PPFI 3TO9A 2ELIA 4WP4A 1P9GA 3KY9A 4UXHA 1KBEA 2CJSC 1K7TA 2DKVA 2JZMA 1TOTA 1K7VA 2J9RA 2GIVA 1IY6A 1TBQR 1BMOA 2ROWA 1CT4I 3OXGA 1M8BA 1FY7A 4FKDA 2E73A 1IW4A 1HEVA 1YTPA 2Y0MA 3D00A 1DS2I 5E3PA 1H0ZA 2LEOA 1SGQI 2LB7A 3CXLA 2JYYA 2JXDA 2K9HA 1V1IA 2L7XA 2OD1A 3BJIA 4AMLA 3HH2C 3RU0A 2M5XA 2V53A 2WVJA 5CCMA 2WGCA 2WCYA 2L8EA 1KMAA 2BUSA 2KMQA 2ENZA 4SGBI 2KMPA 2UZ3A 2P6AC 1XBTA 1CGII 1XX6A 2ARPF 1TURA 4B6DA 1M8CA 1V1HA 5FUVA 5FUXA 3UGLA 4OVOA 2CWHA 3OVOA 3UEYA 5J8FA 1ULKA 5EX3A 2SGFI 1DS3I 1CT2I 1OVOA 2SGPI 2ERWA 1FYBA 1CHOI 5DAEA 1ULMA 3R5BA 5J8CA 1OYVI 2V1CC 2GKRI 2RC4A 1VDDA 2CWFA 2UVOA 2VRWB 3R5AA 3VE5A 1WGCA 1CT0I 2CWGA 2GVIA 2DB6A 2QQCA 2GKVA 1SGRI 2KMOA 1HJAI 3TOAA 1RFHA 1ULNA 1Y1BA 2A20A 5HQ8A 2B0UC 1OMUA 4E1RA 9WGAA 3UFFA 1UVFA 3VDUA 1LR9A 3QWPA 4UXJA 3UGIA 2ODDA 1U5KA 2QQEA 1TUSA 2QQ0A 2B8TA 1PTQA 5JHWC
chains in the Genus database with same CATH topology
5FUWA 3PDNA 1LR7A 3SEKC 3QTLD 2N1AB 1SGDI 3TJQA 3E2IA 1Y1CA 4GI3C 1N13A 1TBNA 4L9MA 2DIPA 1SGNI 3FC3A 1NUBA 2V1CA 2YQPA 1Y8FA 2N52A 1CSOI 2JW6A 1CGJI 1X74A 2W0TA 1AN1I 4E1PA 2QQDA 1PTRA 3VDPA 1FARA 2YUUA 3SGBI 3MEKA 1HDLA 2ORWA 2F3CI 1PCEA 1W4RA 1SGEI 4UXIA 1UUCA 1HPTA 1UVGA 2E5RA 2NU3I 2FNFX 2J87A 1CE3A 2XRCA 2NU1I 3B4VC 1KBFA 1MT1A 1IY5A 1Z7KB 1R79A 2N17A 2SGEI 4HGUA 2JA1A 1PTQA 2SGDI 3GOXA 2NU4I 1BUSA 2NU2I 2ENNA 2QPOA 4JCVE 2LUYA 3OXFA 1FAQA 1LR8A 2GKTI 1SGPI 1TBRR 1TGSI 5EX0A 3E59A 3UGDA 2N71A 5CCLA 1TBOA 3OL0A 1YU6C 2SGQI 1X4SA 2ORVA 1PJUA 3SGQI 4A24A 1W3SA 1XA6A 2OVOA 3OXLA 3UEJA 1SGYI 1OMTA 2KCXA 5HI7A 1TIHA 2KMRA 2NU0I 5FUYA 1R0RI 1PPFI 2ELIA 3KY9A 4UXHA 1KBEA 2CJSC 2JZMA 1TOTA 2J9RA 1IY6A 1TBQR 1BMOA 2ROWA 1CT4I 3OXGA 1M8BA 4FKDA 2E73A 1IW4A 1YTPA 3D00A 1DS2I 1H0ZA 2LEOA 1SGQI 3CXLA 2JYYA 2JXDA 2K9HA 1V1IA 2L7XA 2OD1A 3BJIA 3HH2C 3RU0A 2M5XA 2V53A 2WVJA 5CCMA 2WCYA 2L8EA 1KMAA 2BUSA 2KMQA 2ENZA 4SGBI 2KMPA 2UZ3A 2P6AC 1XBTA 1CGII 2ARPF 1TURA 4B6DA 1M8CA 1V1HA 5FUVA 5FUXA 3UGLA 4OVOA 3OVOA 3UEYA 5EX3A 2SGFI 1DS3I 1CT2I 1OVOA 2SGPI 2ERWA 1FYBA 1CHOI 5DAEA 1OYVI 2V1CC 2GKRI 2VRWB 1VDDA 3VE5A 2GVIA 1CT0I 2DB6A 2QQCA 2GKVA 1SGRI 2KMOA 1HJAI 1RFHA 1Y1BA 2A20A 5HQ8A 2B0UC 1OMUA 4E1RA 3UFFA 1UVFA 3VDUA 1LR9A 3QWPA 4UXJA 3UGIA 2ODDA 1U5KA 2QQEA 1TUSA 2QQ0A 2B8TA 1XX6A 5JHWC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LR7 A;  3SEK C;  3QTL D;  1SGD I;  3TJQ A;  1Y1C A;  4GI3 C;  1N13 A;  1SGN I;  1NUB A;  2N52 A;  1CSO I;  1CGJ I;  1AN1 I;  2QQD A;  3SGB I;  1HDL A;  2F3C I;  1PCE A;  1SGE I;  1UUC A;  1HPT A;  1UVG A;  2NU3 I;  1CE3 A;  2XRC A;  2NU1 I;  3B4V C;  1MT1 A;  1IY5 A;  1Z7K B;  2N17 A;  2SGE I;  4HGU A;  2SGD I;  2NU4 I;  1BUS A;  2NU2 I;  1LR8 A;  2GKT I;  1SGP I;  1TBR R;  1TGS I;  2N71 A;  1YU6 C;  2SGQ I;  1PJU A;  3SGQ I;  2OVO A;  1SGY I;  2KCX A;  1OMT A;  2KMR A;  2NU0 I;  1TIH A;  1R0R I;  1PPF I;  2JZM A;  1IY6 A;  1TBQ R;  1BMO A;  1CT4 I;  1M8B A;  1IW4 A;  1YTP A;  1DS2 I;  1H0Z A;  2LEO A;  1SGQ I;  2JYY A;  2JXD A;  3HH2 C;  2M5X A;  2V53 A;  2WCY A;  1KMA A;  2BUS A;  2KMQ A;  4SGB I;  2KMP A;  2P6A C;  1CGI I;  2ARP F;  1TUR A;  1M8C A;  4OVO A;  3OVO A;  2SGF I;  1DS3 I;  1CT2 I;  1OVO A;  2SGP I;  2ERW A;  1FYB A;  1CHO I;  5DAE A;  1OYV I;  2GKR I;  1CT0 I;  2QQC A;  1SGR I;  2KMO A;  1HJA I;  1Y1B A;  2B0U C;  1OMU A;  1UVF A;  1LR9 A;  1TUS A;  2GKV A;  5JHW C; 
#chains in the Genus database with same CATH topology
 1WTJ A;  3R5C A;  3PDN A;  1LR7 A;  5FUW A;  3SEK C;  3QTL D;  2N1A B;  1SGD I;  3TJQ A;  3E2I A;  1Y1C A;  4GI3 C;  1N13 A;  1TBN A;  4L9M A;  2DIP A;  1SGN I;  3FC3 A;  1NUB A;  2V1C A;  2YQP A;  1Y8F A;  2N52 A;  1CSO I;  2JW6 A;  1Z2I A;  1CGJ I;  3TO7 A;  1X74 A;  2W0T A;  3TOB A;  4DNC A;  1AN1 I;  3QAH A;  4E1P A;  2QQD A;  1PTR A;  1P9Z A;  3VDP A;  1FAR A;  1S20 A;  2YUU A;  3MEK A;  3SGB I;  1HDL A;  2ORW A;  2F3C I;  1PCE A;  1UHA A;  1SGE I;  1W4R A;  5E3Q A;  4UXI A;  1UUC A;  1HPT A;  1UVG A;  2PQ8 A;  2E5R A;  2NU3 I;  2FNF X;  2J87 A;  1CE3 A;  2XRC A;  1NXU A;  2NU1 I;  3B4V C;  1KBF A;  1MT1 A;  2X52 A;  1IY5 A;  1Z7K B;  3R5D A;  1R79 A;  1MJ9 A;  2N17 A;  2SGE I;  4HGU A;  2JA1 A;  3GOX A;  2SGD I;  2NU4 I;  1BUS A;  4MPI A;  2NU2 I;  2ENN A;  1MJA A;  3FSX A;  7WGA A;  3UOE A;  2QPO A;  4JCV E;  2LUY A;  3OXF A;  1FAQ A;  1LR8 A;  2GKT I;  1SGP I;  1TBR R;  1TGS I;  5EX0 A;  3E59 A;  3UGD A;  2N71 A;  2OU2 A;  2OZU A;  2X3T A;  5CCL A;  1TBO A;  3OL0 A;  1YU6 C;  2SGQ I;  1K7U A;  1X4S A;  2RIJ A;  1WKX A;  2ORV A;  1PJU A;  3SGQ I;  4A24 A;  1W3S A;  1XA6 A;  2OVO A;  3OXL A;  5E3R A;  1SGY I;  3UEJ A;  1OMT A;  2KCX A;  5HI7 A;  1TIH A;  1Q9B A;  1MJB A;  1WGT A;  2KMR A;  2NU0 I;  1R0R I;  5FUY A;  3TO6 A;  3FSY A;  1PPF I;  3TO9 A;  2ELI A;  4WP4 A;  1P9G A;  3KY9 A;  4UXH A;  1KBE A;  2CJS C;  1K7T A;  2DKV A;  2JZM A;  1TOT A;  1K7V A;  2J9R A;  2GIV A;  1IY6 A;  1TBQ R;  1BMO A;  2ROW A;  1CT4 I;  3OXG A;  1M8B A;  1FY7 A;  4FKD A;  2E73 A;  1IW4 A;  1HEV A;  1YTP A;  2Y0M A;  3D00 A;  1DS2 I;  5E3P A;  1H0Z A;  2LEO A;  1SGQ I;  2LB7 A;  3CXL A;  2JYY A;  2JXD A;  2K9H A;  1V1I A;  2L7X A;  2OD1 A;  3BJI A;  4AML A;  3HH2 C;  3RU0 A;  2M5X A;  2V53 A;  2WVJ A;  5CCM A;  2WGC A;  2WCY A;  2L8E A;  1KMA A;  2BUS A;  2KMQ A;  2ENZ A;  4SGB I;  2KMP A;  2UZ3 A;  2P6A C;  1XBT A;  1CGI I;  1XX6 A;  2ARP F;  1TUR A;  4B6D A;  1M8C A;  1V1H A;  5FUV A;  5FUX A;  3UGL A;  4OVO A;  2CWH A;  3OVO A;  3UEY A;  5J8F A;  1ULK A;  5EX3 A;  2SGF I;  1DS3 I;  1CT2 I;  1OVO A;  2SGP I;  2ERW A;  1FYB A;  1CHO I;  5DAE A;  1ULM A;  3R5B A;  5J8C A;  1OYV I;  2V1C C;  2GKR I;  2RC4 A;  1VDD A;  2CWF A;  2UVO A;  2VRW B;  3R5A A;  3VE5 A;  1WGC A;  1CT0 I;  2CWG A;  2GVI A;  2DB6 A;  2QQC A;  2GKV A;  1SGR I;  2KMO A;  1HJA I;  3TOA A;  1RFH A;  1ULN A;  1Y1B A;  2A20 A;  5HQ8 A;  2B0U C;  1OMU A;  4E1R A;  9WGA A;  3UFF A;  1UVF A;  3VDU A;  1LR9 A;  3QWP A;  4UXJ A;  3UGI A;  2ODD A;  1U5K A;  2QQE A;  1TUS A;  2QQ0 A;  2B8T A;  1PTQ A;  5JHW C; 
#chains in the Genus database with same CATH homology
 5FUW A;  3PDN A;  1LR7 A;  3SEK C;  3QTL D;  2N1A B;  1SGD I;  3TJQ A;  3E2I A;  1Y1C A;  4GI3 C;  1N13 A;  1TBN A;  4L9M A;  2DIP A;  1SGN I;  3FC3 A;  1NUB A;  2V1C A;  2YQP A;  1Y8F A;  2N52 A;  1CSO I;  2JW6 A;  1CGJ I;  1X74 A;  2W0T A;  1AN1 I;  4E1P A;  2QQD A;  1PTR A;  3VDP A;  1FAR A;  2YUU A;  3SGB I;  3MEK A;  1HDL A;  2ORW A;  2F3C I;  1PCE A;  1W4R A;  1SGE I;  4UXI A;  1UUC A;  1HPT A;  1UVG A;  2E5R A;  2NU3 I;  2FNF X;  2J87 A;  1CE3 A;  2XRC A;  2NU1 I;  3B4V C;  1KBF A;  1MT1 A;  1IY5 A;  1Z7K B;  1R79 A;  2N17 A;  2SGE I;  4HGU A;  2JA1 A;  1PTQ A;  2SGD I;  3GOX A;  2NU4 I;  1BUS A;  2NU2 I;  2ENN A;  2QPO A;  4JCV E;  2LUY A;  3OXF A;  1FAQ A;  1LR8 A;  2GKT I;  1SGP I;  1TBR R;  1TGS I;  5EX0 A;  3E59 A;  3UGD A;  2N71 A;  5CCL A;  1TBO A;  3OL0 A;  1YU6 C;  2SGQ I;  1X4S A;  2ORV A;  1PJU A;  3SGQ I;  4A24 A;  1W3S A;  1XA6 A;  2OVO A;  3OXL A;  3UEJ A;  1SGY I;  1OMT A;  2KCX A;  5HI7 A;  1TIH A;  2KMR A;  2NU0 I;  5FUY A;  1R0R I;  1PPF I;  2ELI A;  3KY9 A;  4UXH A;  1KBE A;  2CJS C;  2JZM A;  1TOT A;  2J9R A;  1IY6 A;  1TBQ R;  1BMO A;  2ROW A;  1CT4 I;  3OXG A;  1M8B A;  4FKD A;  2E73 A;  1IW4 A;  1YTP A;  3D00 A;  1DS2 I;  1H0Z A;  2LEO A;  1SGQ I;  3CXL A;  2JYY A;  2JXD A;  2K9H A;  1V1I A;  2L7X A;  2OD1 A;  3BJI A;  3HH2 C;  3RU0 A;  2M5X A;  2V53 A;  2WVJ A;  5CCM A;  2WCY A;  2L8E A;  1KMA A;  2BUS A;  2KMQ A;  2ENZ A;  4SGB I;  2KMP A;  2UZ3 A;  2P6A C;  1XBT A;  1CGI I;  2ARP F;  1TUR A;  4B6D A;  1M8C A;  1V1H A;  5FUV A;  5FUX A;  3UGL A;  4OVO A;  3OVO A;  3UEY A;  5EX3 A;  2SGF I;  1DS3 I;  1CT2 I;  1OVO A;  2SGP I;  2ERW A;  1FYB A;  1CHO I;  5DAE A;  1OYV I;  2V1C C;  2GKR I;  2VRW B;  1VDD A;  3VE5 A;  2GVI A;  1CT0 I;  2DB6 A;  2QQC A;  2GKV A;  1SGR I;  2KMO A;  1HJA I;  1RFH A;  1Y1B A;  2A20 A;  5HQ8 A;  2B0U C;  1OMU A;  4E1R A;  3UFF A;  1UVF A;  3VDU A;  1LR9 A;  3QWP A;  4UXJ A;  3UGI A;  2ODD A;  1U5K A;  2QQE A;  1TUS A;  2QQ0 A;  2B8T A;  1XX6 A;  5JHW C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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