1SGRI

Leu 18 variant of turkey ovomucoid inhibitor third domain complexed with streptomyces griseus proteinase b
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
51
structure length
51
Chain Sequence
VDCSEYPKPACTLEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Water molecules participate in proteinase-inhibitor interactions: crystal structures of Leu18, Ala18, and Gly18 variants of turkey ovomucoid inhibitor third domain complexed with Streptomyces griseus proteinase B.
pubmed rcsb
molecule tags Complex (serine protease/inhibitor)
source organism Streptomyces griseus
molecule keywords STREPTOMYCES GRISEUS PROTEINASE B
total genus 13
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 1995-05-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1sgrI00
1LR9A 3TJQA 1TBRR 3HH2C 2GKRI 1NUBA 2BUSA 1SGEI 1PCEA 1CGII 1MT1A 1SGYI 1M8CA 1CE3A 1Z7KB 1R0RI 1SGNI 1BUSA 1CT4I 2P6AC 1HJAI 1HDLA 2QQCA 2NU4I 1SGRI 2V53A 1N13A 2JYYA 1YTPA 2NU0I 3SEKC 1UVGA 1SGPI 2ARPF 2B0UC 3SGBI 1FYBA 1M8BA 1Y1BA 1OVOA 1DS3I 1IW4A 1SGDI 1IY6A 1OMTA 1Y1CA 2KCXA 2QQDA 2XRCA 5JHWC 3OVOA 1HPTA 1TIHA 2GKVA 1OYVI 1BMOA 2SGPI 1UUCA 1TURA 1TBQR 2LEOA 1TGSI 2WCYA 2JZMA 2M5XA 1H0ZA 5DAEA 2KMOA 1PJUA 2KMQA 2SGEI 4HGUA 2JXDA 3SGQI 2N52A 2NU2I 1UVFA 1CT2I 1KMAA 1OMUA 1IY5A 2ERWA 2SGDI 2N17A 3B4VC 2NU1I 4OVOA 1LR7A 1TUSA 1CSOI 2F3CI 2NU3I 1LR8A 1AN1I 2SGQI 2OVOA 1CGJI 2KMRA 2SGFI 3QTLD 2N71A 4GI3C 2GKTI 1PPFI 4SGBI 1YU6C 1CHOI 1SGQI 1DS2I 2KMPA 1CT0I
chains in the Genus database with same CATH superfamily
1LR9A 3D00A 2QPOA 3TJQA 1TBRR 3TO6A 1WGCA 3E59A 2WGCA 1XX6A 2K9HA 3HH2C 3OXLA 1K7UA 1W3SA 3R5DA 2GKRI 1NUBA 1XA6A 9WGAA 2CWHA 2BUSA 1WGTA 1SGEI 2UVOA 1SGYI 1PCEA 1CGII 1MT1A 1Q9BA 2WVJA 3RU0A 1M8CA 2QQEA 2VRWB 1CE3A 1Z7KB 1R0RI 1ULKA 5FUVA 1SGNI 3QAHA 2JA1A 1BUSA 5E3RA 1CT4I 2P6AC 3UGIA 2FNFX 1HJAI 3TOAA 4E1RA 1HDLA 1R79A 3OXFA 2E5RA 1PTQA 1XBTA 2J9RA 2X3TA 2LUYA 2QQCA 2X52A 5EX3A 1X74A 2YQPA 2OU2A 2NU4I 3TO7A 1SGRI 1ULNA 2A20A 2V53A 5CCMA 1FAQA 2E73A 1N13A 2RC4A 2JYYA 1YTPA 2NU0I 3SEKC 4L9MA 1UVGA 5HI7A 1SGPI 5FUWA 2ARPF 2UZ3A 1K7VA 1PTRA 2B0UC 3SGBI 2DB6A 2V1CA 1FYBA 1M8BA 1Y1BA 2QQ0A 1UHAA 1FY7A 4UXHA 1ULMA 3FC3A 1TOTA 1CT0I 1OVOA 1X4SA 2ENZA 5J8CA 1DS3I 3BJIA 2CWGA 4WP4A 1SGDI 2CWFA 1OMTA 3CXLA 1IW4A 1Y1CA 2V1CC 2KCXA 3UFFA 1IY6A 2QQDA 2ORWA 2XRCA 5JHWC 3OVOA 1HPTA 1TIHA 2GKVA 1MJBA 3R5CA 5FUXA 2ELIA 4UXJA 1OYVI 3GOXA 1BMOA 1U5KA 2DKVA 1UUCA 2SGPI 1TURA 1TBQR 2LEOA 1VDDA 2JW6A 4AMLA 1P9ZA 3FSXA 1TGSI 2ROWA 3E2IA 1V1HA 1FARA 4UXIA 7WGAA 2WCYA 2JZMA 2LB7A 2M5XA 3FSYA 1H0ZA 1NXUA 5DAEA 5HQ8A 2KMOA 4DNCA 1PJUA 2KMQA 2N1AB 2SGEI 2OD1A 1K7TA 4HGUA 2JXDA 2ORVA 4FKDA 3TO9A 3UOEA 2ODDA 2L8EA 3SGQI 2N52A 2PQ8A 1MJAA 2NU2I 1W4RA 3KY9A 1UVFA 2DIPA 3UEJA 1CT2I 2W0TA 2RIJA 2Y0MA 2CJSC 1OMUA 3R5BA 3R5AA 1KMAA 2OZUA 1WTJA 1IY5A 2ENNA 2GIVA 5E3PA 2ERWA 3TOBA 2SGDI 3OL0A 5E3QA 1TBNA 2N17A 3B4VC 2NU1I 3PDNA 4OVOA 1LR7A 1TUSA 1Z2IA 3VDPA 2L7XA 1CSOI 1V1IA 2F3CI 2GVIA 2NU3I 2YUUA 1KBFA 5CCLA 5FUYA 4E1PA 1LR8A 1AN1I 4B6DA 1S20A 2OVOA 1CGJI 2SGQI 2KMRA 3UGLA 2SGFI 3QTLD 3QWPA 3MEKA 3UGDA 1WKXA 1KBEA 2N71A 1RFHA 5J8FA 4GI3C 2GKTI 2B8TA 1PPFI 2J87A 4SGBI 1YU6C 3UEYA 1TBOA 1CHOI 1MJ9A 1SGQI 4JCVE 1DS2I 3VDUA 1HEVA 3OXGA 3VE5A 4MPIA 4A24A 5EX0A 2KMPA 1Y8FA 1P9GA
chains in the Genus database with same CATH topology
1LR9A 3D00A 2QPOA 3TJQA 1TBRR 3E59A 1XX6A 2K9HA 3HH2C 3OXLA 1W3SA 2GKRI 1NUBA 1XA6A 2BUSA 3CXLA 1SGEI 2WVJA 1PCEA 1CGII 1MT1A 1SGYI 3RU0A 1M8CA 2QQEA 2VRWB 1CE3A 1Z7KB 1R0RI 5FUVA 1SGNI 2JA1A 1BUSA 1CT4I 2P6AC 3UGIA 2FNFX 1HJAI 4E1RA 1HDLA 1R79A 3OXFA 2E5RA 1PTQA 1XBTA 2J9RA 5EX3A 2LUYA 2QQCA 1X74A 2YQPA 2NU4I 1SGRI 2V53A 2A20A 5CCMA 1FAQA 2E73A 1N13A 2JYYA 1YTPA 2NU0I 3SEKC 4L9MA 1UVGA 5HI7A 1SGPI 5FUWA 2ARPF 2UZ3A 1PTRA 2B0UC 3SGBI 2DB6A 2V1CA 1FYBA 1M8BA 1Y1BA 2QQ0A 4UXHA 3FC3A 1TOTA 1OVOA 1X4SA 2ENZA 1DS3I 3BJIA 1IW4A 1SGDI 1IY6A 1OMTA 1Y1CA 2V1CC 2KCXA 3UFFA 2QQDA 2ORWA 2XRCA 5JHWC 3OVOA 1HPTA 1TIHA 2GKVA 5FUXA 2ELIA 4UXJA 1OYVI 3GOXA 1BMOA 1U5KA 2SGPI 1UUCA 1TURA 1TBQR 2LEOA 1VDDA 2JW6A 1TGSI 2ROWA 3E2IA 1V1HA 1FARA 4UXIA 2WCYA 2JZMA 2M5XA 1H0ZA 5DAEA 5HQ8A 2KMOA 1PJUA 2KMQA 2N1AB 2SGEI 2OD1A 4HGUA 2JXDA 2ORVA 4FKDA 2ODDA 2L8EA 3SGQI 2N52A 2NU2I 1W4RA 3KY9A 1UVFA 2DIPA 3UEJA 1CT2I 2W0TA 1KMAA 2CJSC 1OMUA 1IY5A 2ENNA 2ERWA 2SGDI 3OL0A 1TBNA 2N17A 3B4VC 2NU1I 3PDNA 4OVOA 1LR7A 1TUSA 3VDPA 2L7XA 1CSOI 1V1IA 2F3CI 2GVIA 2NU3I 2YUUA 1KBFA 5CCLA 5FUYA 4E1PA 1LR8A 1AN1I 4B6DA 2SGQI 2OVOA 1CGJI 3UGLA 2KMRA 2SGFI 3QTLD 3QWPA 3MEKA 3UGDA 1KBEA 2N71A 1RFHA 4GI3C 2GKTI 2B8TA 1PPFI 2J87A 4SGBI 1YU6C 3UEYA 1TBOA 1CHOI 1SGQI 4JCVE 1DS2I 3VDUA 3OXGA 3VE5A 4A24A 5EX0A 2KMPA 1Y8FA 1CT0I
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LR9 A;  3TJQ A;  1TBR R;  3HH2 C;  2GKR I;  1NUB A;  2BUS A;  1SGE I;  1PCE A;  1CGI I;  1MT1 A;  1SGY I;  1M8C A;  1CE3 A;  1Z7K B;  1R0R I;  1SGN I;  1BUS A;  1CT4 I;  2P6A C;  1HJA I;  1HDL A;  2QQC A;  2NU4 I;  1SGR I;  2V53 A;  1N13 A;  2JYY A;  1YTP A;  2NU0 I;  3SEK C;  1UVG A;  1SGP I;  2ARP F;  2B0U C;  3SGB I;  1FYB A;  1M8B A;  1Y1B A;  1OVO A;  1DS3 I;  1IW4 A;  1SGD I;  1IY6 A;  1OMT A;  1Y1C A;  2KCX A;  2QQD A;  2XRC A;  5JHW C;  3OVO A;  1HPT A;  1TIH A;  2GKV A;  1OYV I;  1BMO A;  2SGP I;  1UUC A;  1TUR A;  1TBQ R;  2LEO A;  1TGS I;  2WCY A;  2JZM A;  2M5X A;  1H0Z A;  5DAE A;  2KMO A;  1PJU A;  2KMQ A;  2SGE I;  4HGU A;  2JXD A;  3SGQ I;  2N52 A;  2NU2 I;  1UVF A;  1CT2 I;  1KMA A;  1OMU A;  1IY5 A;  2ERW A;  2SGD I;  2N17 A;  3B4V C;  2NU1 I;  4OVO A;  1LR7 A;  1TUS A;  1CSO I;  2F3C I;  2NU3 I;  1LR8 A;  1AN1 I;  2SGQ I;  2OVO A;  1CGJ I;  2KMR A;  2SGF I;  3QTL D;  2N71 A;  4GI3 C;  2GKT I;  1PPF I;  4SGB I;  1YU6 C;  1CHO I;  1SGQ I;  1DS2 I;  2KMP A;  1CT0 I; 
#chains in the Genus database with same CATH topology
 1LR9 A;  3D00 A;  2QPO A;  3TJQ A;  1TBR R;  3TO6 A;  1WGC A;  3E59 A;  2WGC A;  1XX6 A;  2K9H A;  3HH2 C;  3OXL A;  1K7U A;  1W3S A;  3R5D A;  2GKR I;  1NUB A;  1XA6 A;  9WGA A;  2CWH A;  2BUS A;  1WGT A;  1SGE I;  2UVO A;  1SGY I;  1PCE A;  1CGI I;  1MT1 A;  1Q9B A;  2WVJ A;  3RU0 A;  1M8C A;  2QQE A;  2VRW B;  1CE3 A;  1Z7K B;  1R0R I;  1ULK A;  5FUV A;  1SGN I;  3QAH A;  2JA1 A;  1BUS A;  5E3R A;  1CT4 I;  2P6A C;  3UGI A;  2FNF X;  1HJA I;  3TOA A;  4E1R A;  1HDL A;  1R79 A;  3OXF A;  2E5R A;  1PTQ A;  1XBT A;  2J9R A;  2X3T A;  2LUY A;  2QQC A;  2X52 A;  5EX3 A;  1X74 A;  2YQP A;  2OU2 A;  2NU4 I;  3TO7 A;  1SGR I;  1ULN A;  2A20 A;  2V53 A;  5CCM A;  1FAQ A;  2E73 A;  1N13 A;  2RC4 A;  2JYY A;  1YTP A;  2NU0 I;  3SEK C;  4L9M A;  1UVG A;  5HI7 A;  1SGP I;  5FUW A;  2ARP F;  2UZ3 A;  1K7V A;  1PTR A;  2B0U C;  3SGB I;  2DB6 A;  2V1C A;  1FYB A;  1M8B A;  1Y1B A;  2QQ0 A;  1UHA A;  1FY7 A;  4UXH A;  1ULM A;  3FC3 A;  1TOT A;  1CT0 I;  1OVO A;  1X4S A;  2ENZ A;  5J8C A;  1DS3 I;  3BJI A;  2CWG A;  4WP4 A;  1SGD I;  2CWF A;  1OMT A;  3CXL A;  1IW4 A;  1Y1C A;  2V1C C;  2KCX A;  3UFF A;  1IY6 A;  2QQD A;  2ORW A;  2XRC A;  5JHW C;  3OVO A;  1HPT A;  1TIH A;  2GKV A;  1MJB A;  3R5C A;  5FUX A;  2ELI A;  4UXJ A;  1OYV I;  3GOX A;  1BMO A;  1U5K A;  2DKV A;  1UUC A;  2SGP I;  1TUR A;  1TBQ R;  2LEO A;  1VDD A;  2JW6 A;  4AML A;  1P9Z A;  3FSX A;  1TGS I;  2ROW A;  3E2I A;  1V1H A;  1FAR A;  4UXI A;  7WGA A;  2WCY A;  2JZM A;  2LB7 A;  2M5X A;  3FSY A;  1H0Z A;  1NXU A;  5DAE A;  5HQ8 A;  2KMO A;  4DNC A;  1PJU A;  2KMQ A;  2N1A B;  2SGE I;  2OD1 A;  1K7T A;  4HGU A;  2JXD A;  2ORV A;  4FKD A;  3TO9 A;  3UOE A;  2ODD A;  2L8E A;  3SGQ I;  2N52 A;  2PQ8 A;  1MJA A;  2NU2 I;  1W4R A;  3KY9 A;  1UVF A;  2DIP A;  3UEJ A;  1CT2 I;  2W0T A;  2RIJ A;  2Y0M A;  2CJS C;  1OMU A;  3R5B A;  3R5A A;  1KMA A;  2OZU A;  1WTJ A;  1IY5 A;  2ENN A;  2GIV A;  5E3P A;  2ERW A;  3TOB A;  2SGD I;  3OL0 A;  5E3Q A;  1TBN A;  2N17 A;  3B4V C;  2NU1 I;  3PDN A;  4OVO A;  1LR7 A;  1TUS A;  1Z2I A;  3VDP A;  2L7X A;  1CSO I;  1V1I A;  2F3C I;  2GVI A;  2NU3 I;  2YUU A;  1KBF A;  5CCL A;  5FUY A;  4E1P A;  1LR8 A;  1AN1 I;  4B6D A;  1S20 A;  2OVO A;  1CGJ I;  2SGQ I;  2KMR A;  3UGL A;  2SGF I;  3QTL D;  3QWP A;  3MEK A;  3UGD A;  1WKX A;  1KBE A;  2N71 A;  1RFH A;  5J8F A;  4GI3 C;  2GKT I;  2B8T A;  1PPF I;  2J87 A;  4SGB I;  1YU6 C;  3UEY A;  1TBO A;  1CHO I;  1MJ9 A;  1SGQ I;  4JCV E;  1DS2 I;  3VDU A;  1HEV A;  3OXG A;  3VE5 A;  4MPI A;  4A24 A;  5EX0 A;  2KMP A;  1Y8F A;  1P9G A; 
#chains in the Genus database with same CATH homology
 1LR9 A;  3D00 A;  2QPO A;  3TJQ A;  1TBR R;  3E59 A;  1XX6 A;  2K9H A;  3HH2 C;  3OXL A;  1W3S A;  2GKR I;  1NUB A;  1XA6 A;  2BUS A;  3CXL A;  1SGE I;  2WVJ A;  1PCE A;  1CGI I;  1MT1 A;  1SGY I;  3RU0 A;  1M8C A;  2QQE A;  2VRW B;  1CE3 A;  1Z7K B;  1R0R I;  5FUV A;  1SGN I;  2JA1 A;  1BUS A;  1CT4 I;  2P6A C;  3UGI A;  2FNF X;  1HJA I;  4E1R A;  1HDL A;  1R79 A;  3OXF A;  2E5R A;  1PTQ A;  1XBT A;  2J9R A;  5EX3 A;  2LUY A;  2QQC A;  1X74 A;  2YQP A;  2NU4 I;  1SGR I;  2V53 A;  2A20 A;  5CCM A;  1FAQ A;  2E73 A;  1N13 A;  2JYY A;  1YTP A;  2NU0 I;  3SEK C;  4L9M A;  1UVG A;  5HI7 A;  1SGP I;  5FUW A;  2ARP F;  2UZ3 A;  1PTR A;  2B0U C;  3SGB I;  2DB6 A;  2V1C A;  1FYB A;  1M8B A;  1Y1B A;  2QQ0 A;  4UXH A;  3FC3 A;  1TOT A;  1OVO A;  1X4S A;  2ENZ A;  1DS3 I;  3BJI A;  1IW4 A;  1SGD I;  1IY6 A;  1OMT A;  1Y1C A;  2V1C C;  2KCX A;  3UFF A;  2QQD A;  2ORW A;  2XRC A;  5JHW C;  3OVO A;  1HPT A;  1TIH A;  2GKV A;  5FUX A;  2ELI A;  4UXJ A;  1OYV I;  3GOX A;  1BMO A;  1U5K A;  2SGP I;  1UUC A;  1TUR A;  1TBQ R;  2LEO A;  1VDD A;  2JW6 A;  1TGS I;  2ROW A;  3E2I A;  1V1H A;  1FAR A;  4UXI A;  2WCY A;  2JZM A;  2M5X A;  1H0Z A;  5DAE A;  5HQ8 A;  2KMO A;  1PJU A;  2KMQ A;  2N1A B;  2SGE I;  2OD1 A;  4HGU A;  2JXD A;  2ORV A;  4FKD A;  2ODD A;  2L8E A;  3SGQ I;  2N52 A;  2NU2 I;  1W4R A;  3KY9 A;  1UVF A;  2DIP A;  3UEJ A;  1CT2 I;  2W0T A;  1KMA A;  2CJS C;  1OMU A;  1IY5 A;  2ENN A;  2ERW A;  2SGD I;  3OL0 A;  1TBN A;  2N17 A;  3B4V C;  2NU1 I;  3PDN A;  4OVO A;  1LR7 A;  1TUS A;  3VDP A;  2L7X A;  1CSO I;  1V1I A;  2F3C I;  2GVI A;  2NU3 I;  2YUU A;  1KBF A;  5CCL A;  5FUY A;  4E1P A;  1LR8 A;  1AN1 I;  4B6D A;  2SGQ I;  2OVO A;  1CGJ I;  3UGL A;  2KMR A;  2SGF I;  3QTL D;  3QWP A;  3MEK A;  3UGD A;  1KBE A;  2N71 A;  1RFH A;  4GI3 C;  2GKT I;  2B8T A;  1PPF I;  2J87 A;  4SGB I;  1YU6 C;  3UEY A;  1TBO A;  1CHO I;  1SGQ I;  4JCV E;  1DS2 I;  3VDU A;  3OXG A;  3VE5 A;  4A24 A;  5EX0 A;  2KMP A;  1Y8F A;  1CT0 I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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