1UUCA

Solution structure of a chimeric lekti-domain
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
55
structure length
55
Chain Sequence
KNEDQEMCHEFQAFMKNGKLFCPQDKKPIQSLDGIMFINKCATCKMILEKEAKSQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Solution Structure of a Chimeric Lekti Domain Reveals a Chameleon Sequence
pubmed doi rcsb
molecule tags Serine proteinase inhibitor
source organism Homo sapiens
molecule keywords SERINE PROTEASE INHIBITOR KAZAL-TYPE 5
total genus 13
structure length 55
sequence length 55
ec nomenclature
pdb deposition date 2003-12-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1uucA00
2SGQI 1PCEA 1KMAA 1DS2I 2KMQA 2WCYA 1OVOA 1HDLA 2QQDA 1M8BA 1YU6C 1BMOA 1TBRR 1YTPA 2GKTI 1Y1BA 2GKVA 1CSOI 2SGDI 2SGFI 1CE3A 1OMTA 1R0RI 1UVFA 1IY5A 2JZMA 1CT4I 2NU1I 2SGPI 1TIHA 2N17A 1M8CA 2ERWA 2NU3I 2KMPA 2JYYA 1SGYI 1OMUA 1CHOI 4GI3C 1HJAI 1TBQR 2N71A 1SGDI 1SGNI 1SGQI 3B4VC 1PJUA 2KMOA 1SGPI 2NU2I 1SGEI 2GKRI 1BUSA 5DAEA 2P6AC 1TGSI 2KMRA 1CGJI 3TJQA 1PPFI 1DS3I 1CT0I 2ARPF 1NUBA 2BUSA 1MT1A 2JXDA 1Z7KB 4OVOA 2M5XA 1UVGA 1TUSA 1FYBA 2NU0I 1LR8A 1UUCA 2OVOA 1CT2I 2XRCA 4SGBI 3QTLD 1H0ZA 1HPTA 2NU4I 5JHWC 1IW4A 4HGUA 2N52A 3HH2C 1CGII 2KCXA 2F3CI 2QQCA 1IY6A 1OYVI 3OVOA 1TURA 1LR7A 3SGBI 1Y1CA 1N13A 2B0UC 2LEOA 2V53A 3SEKC 1AN1I 2SGEI 3SGQI 1LR9A 1SGRI
chains in the Genus database with same CATH superfamily
5HQ8A 2ENZA 2L7XA 3UGLA 2JA1A 2N1AB 1KBFA 2SGQI 3RU0A 1PCEA 1TBNA 1Z2IA 2X52A 2LUYA 2B8TA 1DS2I 1KMAA 2KMQA 2CWFA 2CWGA 1WKXA 3TOBA 5FUVA 3TO7A 2WCYA 1X4SA 1OVOA 4AMLA 1ULMA 5HI7A 2ELIA 2FNFX 1HDLA 2QQDA 1MJAA 1M8BA 2GIVA 1YU6C 1BMOA 1TOTA 1TBRR 3QAHA 1YTPA 2GKTI 1Y1BA 3TO6A 4UXJA 5CCLA 3OXGA 2GKVA 1CSOI 4WP4A 1K7UA 2UVOA 3UGIA 2SGDI 2SGFI 5FUWA 1CE3A 1OMTA 1R0RI 1UVFA 1Q9BA 2X3TA 1IY5A 5E3RA 2OD1A 2JZMA 1CT4I 1NXUA 3R5BA 2ROWA 3UEJA 2NU1I 1FY7A 3UGDA 5J8CA 2SGPI 5E3QA 2UZ3A 1TIHA 3UEYA 2N17A 1M8CA 2ERWA 3PDNA 2NU3I 5FUYA 3VDPA 1BUSA 1FARA 2KMPA 1X74A 2JYYA 1SGYI 2DB6A 2ENNA 1OMUA 1CHOI 3R5AA 4GI3C 3KY9A 2VRWB 1ULKA 3UOEA 1HJAI 1TBQR 2N71A 4B6DA 2ODDA 1SGDI 1WTJA 1SGNI 5EX3A 2LB7A 2V1CA 1SGQI 2J9RA 3B4VC 1PJUA 1WGTA 1ULNA 1Y8FA 4L9MA 1WGCA 2J87A 3E59A 1FAQA 2KMOA 1SGPI 1XX6A 2NU2I 1SGEI 9WGAA 1KBEA 2GKRI 3TOAA 3VE5A 5J8FA 2A20A 2CJSC 2YQPA 2P6AC 3FSYA 5DAEA 5EX0A 5FUXA 1TGSI 2KMRA 1S20A 1CGJI 1XA6A 4E1PA 3TJQA 3CXLA 1K7TA 3E2IA 1PPFI 1DS3I 1CT0I 4FKDA 2L8EA 2RC4A 1TBOA 1P9ZA 2ARPF 3OXFA 2V1CC 1NUBA 2BUSA 1MT1A 2QQEA 2JXDA 1Z7KB 4OVOA 2QQ0A 4A24A 1MJBA 4E1RA 1PTQA 2DKVA 1UVGA 2M5XA 1TUSA 1U5KA 3TO9A 1FYBA 2NU0I 1LR8A 2ORWA 2RIJA 1XBTA 3GOXA 1UUCA 1R79A 2OVOA 3OXLA 3UFFA 3FC3A 1V1HA 1CT2I 2XRCA 4SGBI 3QTLD 1H0ZA 1UHAA 1HPTA 2OU2A 3FSXA 3QWPA 2NU4I 5JHWC 2WVJA 1IW4A 4HGUA 3R5DA 1RFHA 4UXHA 2QPOA 2JW6A 7WGAA 2K9HA 1MJ9A 3R5CA 2N52A 5CCMA 3HH2C 2WGCA 1CGII 2KCXA 2F3CI 2OZUA 2QQCA 2Y0MA 1IY6A 4DNCA 1OYVI 2ORVA 3OVOA 1TURA 3VDUA 1V1IA 2E73A 3MEKA 1LR7A 2PQ8A 5E3PA 3SGBI 1Y1CA 1N13A 4MPIA 1HEVA 1W3SA 3D00A 2B0UC 1PTRA 1VDDA 4UXIA 2W0TA 1W4RA 2GVIA 3OL0A 2LEOA 2CWHA 2E5RA 2V53A 1K7VA 1AN1I 1P9GA 3SEKC 2YUUA 2DIPA 2SGEI 3SGQI 4JCVE 1LR9A 3BJIA 1SGRI
chains in the Genus database with same CATH topology
5HQ8A 2ENZA 2L7XA 3UGLA 2JA1A 2N1AB 1KBFA 2SGQI 3RU0A 1PCEA 1TBNA 2LUYA 2B8TA 1DS2I 1KMAA 2KMQA 5FUVA 2WCYA 1X4SA 1OVOA 5HI7A 2ELIA 2FNFX 1HDLA 2QQDA 1M8BA 1YU6C 1BMOA 1TOTA 1TBRR 1YTPA 2GKTI 1Y1BA 4UXJA 5CCLA 3OXGA 2GKVA 1CSOI 3UGIA 2SGDI 2SGFI 5FUWA 1CE3A 1OMTA 1R0RI 1UVFA 1IY5A 2OD1A 2JZMA 1CT4I 2ROWA 3UEJA 2NU1I 3UGDA 2SGPI 2UZ3A 1TIHA 3UEYA 2N17A 1M8CA 2ERWA 3PDNA 2NU3I 5FUYA 3VDPA 1FARA 2KMPA 1X74A 2JYYA 1SGYI 2DB6A 2ENNA 1OMUA 1CHOI 4GI3C 3KY9A 2VRWB 1HJAI 1TBQR 2N71A 4B6DA 2ODDA 1SGDI 5EX3A 1SGNI 2V1CA 1SGQI 2J9RA 3B4VC 1PJUA 1Y8FA 4L9MA 2J87A 3E59A 1FAQA 2KMOA 1XX6A 1SGPI 2NU2I 1SGEI 1KBEA 2GKRI 3VE5A 1BUSA 2A20A 2CJSC 2YQPA 2P6AC 5DAEA 5EX0A 5FUXA 1TGSI 2KMRA 1CGJI 1XA6A 4E1PA 3TJQA 3CXLA 3E2IA 1PPFI 1DS3I 1CT0I 4FKDA 2L8EA 1TBOA 2ARPF 3OXFA 2V1CC 1NUBA 2BUSA 1MT1A 2QQEA 2JXDA 1Z7KB 4OVOA 2QQ0A 4A24A 4E1RA 1PTQA 2M5XA 1UVGA 1TUSA 1U5KA 1FYBA 2NU0I 1LR8A 2ORWA 1XBTA 3GOXA 1UUCA 1R79A 2OVOA 3OXLA 3UFFA 3FC3A 1V1HA 1CT2I 2XRCA 4SGBI 3QTLD 1H0ZA 1HPTA 3QWPA 2NU4I 5JHWC 2WVJA 1IW4A 4HGUA 1RFHA 4UXHA 2QPOA 2JW6A 2K9HA 2N52A 5CCMA 3HH2C 1CGII 2KCXA 2F3CI 2QQCA 1IY6A 1OYVI 2ORVA 3OVOA 1TURA 3VDUA 1V1IA 2E73A 3MEKA 1LR7A 3SGBI 1Y1CA 1N13A 1W3SA 3D00A 2B0UC 1PTRA 1VDDA 4UXIA 2W0TA 1W4RA 2GVIA 3OL0A 2LEOA 2E5RA 2V53A 3SEKC 1AN1I 2YUUA 2DIPA 2SGEI 3SGQI 4JCVE 1LR9A 3BJIA 1SGRI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2SGQ I;  1PCE A;  1KMA A;  1DS2 I;  2KMQ A;  2WCY A;  1OVO A;  1HDL A;  2QQD A;  1M8B A;  1YU6 C;  1BMO A;  1TBR R;  1YTP A;  2GKT I;  1Y1B A;  2GKV A;  1CSO I;  2SGD I;  2SGF I;  1CE3 A;  1OMT A;  1R0R I;  1UVF A;  1IY5 A;  2JZM A;  1CT4 I;  2NU1 I;  2SGP I;  1TIH A;  2N17 A;  1M8C A;  2ERW A;  2NU3 I;  2KMP A;  2JYY A;  1SGY I;  1OMU A;  1CHO I;  4GI3 C;  1HJA I;  1TBQ R;  2N71 A;  1SGD I;  1SGN I;  1SGQ I;  3B4V C;  1PJU A;  2KMO A;  1SGP I;  2NU2 I;  1SGE I;  2GKR I;  1BUS A;  5DAE A;  2P6A C;  1TGS I;  2KMR A;  1CGJ I;  3TJQ A;  1PPF I;  1DS3 I;  1CT0 I;  2ARP F;  1NUB A;  2BUS A;  1MT1 A;  2JXD A;  1Z7K B;  4OVO A;  2M5X A;  1UVG A;  1TUS A;  1FYB A;  2NU0 I;  1LR8 A;  1UUC A;  2OVO A;  1CT2 I;  2XRC A;  4SGB I;  3QTL D;  1H0Z A;  1HPT A;  2NU4 I;  5JHW C;  1IW4 A;  4HGU A;  2N52 A;  3HH2 C;  1CGI I;  2KCX A;  2F3C I;  2QQC A;  1IY6 A;  1OYV I;  3OVO A;  1TUR A;  1LR7 A;  3SGB I;  1Y1C A;  1N13 A;  2B0U C;  2LEO A;  2V53 A;  3SEK C;  1AN1 I;  2SGE I;  3SGQ I;  1LR9 A;  1SGR I; 
#chains in the Genus database with same CATH topology
 5HQ8 A;  2ENZ A;  2L7X A;  3UGL A;  2JA1 A;  2N1A B;  1KBF A;  2SGQ I;  3RU0 A;  1PCE A;  1TBN A;  1Z2I A;  2X52 A;  2LUY A;  2B8T A;  1DS2 I;  1KMA A;  2KMQ A;  2CWF A;  2CWG A;  1WKX A;  3TOB A;  5FUV A;  3TO7 A;  2WCY A;  1X4S A;  1OVO A;  4AML A;  1ULM A;  5HI7 A;  2ELI A;  2FNF X;  1HDL A;  2QQD A;  1MJA A;  1M8B A;  2GIV A;  1YU6 C;  1BMO A;  1TOT A;  1TBR R;  3QAH A;  1YTP A;  2GKT I;  1Y1B A;  3TO6 A;  4UXJ A;  5CCL A;  3OXG A;  2GKV A;  1CSO I;  4WP4 A;  1K7U A;  2UVO A;  3UGI A;  2SGD I;  2SGF I;  5FUW A;  1CE3 A;  1OMT A;  1R0R I;  1UVF A;  1Q9B A;  2X3T A;  1IY5 A;  5E3R A;  2OD1 A;  2JZM A;  1CT4 I;  1NXU A;  3R5B A;  2ROW A;  3UEJ A;  2NU1 I;  1FY7 A;  3UGD A;  5J8C A;  2SGP I;  5E3Q A;  2UZ3 A;  1TIH A;  3UEY A;  2N17 A;  1M8C A;  2ERW A;  3PDN A;  2NU3 I;  5FUY A;  3VDP A;  1BUS A;  1FAR A;  2KMP A;  1X74 A;  2JYY A;  1SGY I;  2DB6 A;  2ENN A;  1OMU A;  1CHO I;  3R5A A;  4GI3 C;  3KY9 A;  2VRW B;  1ULK A;  3UOE A;  1HJA I;  1TBQ R;  2N71 A;  4B6D A;  2ODD A;  1SGD I;  1WTJ A;  1SGN I;  5EX3 A;  2LB7 A;  2V1C A;  1SGQ I;  2J9R A;  3B4V C;  1PJU A;  1WGT A;  1ULN A;  1Y8F A;  4L9M A;  1WGC A;  2J87 A;  3E59 A;  1FAQ A;  2KMO A;  1SGP I;  1XX6 A;  2NU2 I;  1SGE I;  9WGA A;  1KBE A;  2GKR I;  3TOA A;  3VE5 A;  5J8F A;  2A20 A;  2CJS C;  2YQP A;  2P6A C;  3FSY A;  5DAE A;  5EX0 A;  5FUX A;  1TGS I;  2KMR A;  1S20 A;  1CGJ I;  1XA6 A;  4E1P A;  3TJQ A;  3CXL A;  1K7T A;  3E2I A;  1PPF I;  1DS3 I;  1CT0 I;  4FKD A;  2L8E A;  2RC4 A;  1TBO A;  1P9Z A;  2ARP F;  3OXF A;  2V1C C;  1NUB A;  2BUS A;  1MT1 A;  2QQE A;  2JXD A;  1Z7K B;  4OVO A;  2QQ0 A;  4A24 A;  1MJB A;  4E1R A;  1PTQ A;  2DKV A;  1UVG A;  2M5X A;  1TUS A;  1U5K A;  3TO9 A;  1FYB A;  2NU0 I;  1LR8 A;  2ORW A;  2RIJ A;  1XBT A;  3GOX A;  1UUC A;  1R79 A;  2OVO A;  3OXL A;  3UFF A;  3FC3 A;  1V1H A;  1CT2 I;  2XRC A;  4SGB I;  3QTL D;  1H0Z A;  1UHA A;  1HPT A;  2OU2 A;  3FSX A;  3QWP A;  2NU4 I;  5JHW C;  2WVJ A;  1IW4 A;  4HGU A;  3R5D A;  1RFH A;  4UXH A;  2QPO A;  2JW6 A;  7WGA A;  2K9H A;  1MJ9 A;  3R5C A;  2N52 A;  5CCM A;  3HH2 C;  2WGC A;  1CGI I;  2KCX A;  2F3C I;  2OZU A;  2QQC A;  2Y0M A;  1IY6 A;  4DNC A;  1OYV I;  2ORV A;  3OVO A;  1TUR A;  3VDU A;  1V1I A;  2E73 A;  3MEK A;  1LR7 A;  2PQ8 A;  5E3P A;  3SGB I;  1Y1C A;  1N13 A;  4MPI A;  1HEV A;  1W3S A;  3D00 A;  2B0U C;  1PTR A;  1VDD A;  4UXI A;  2W0T A;  1W4R A;  2GVI A;  3OL0 A;  2LEO A;  2CWH A;  2E5R A;  2V53 A;  1K7V A;  1AN1 I;  1P9G A;  3SEK C;  2YUU A;  2DIP A;  2SGE I;  3SGQ I;  4JCV E;  1LR9 A;  3BJI A;  1SGR I; 
#chains in the Genus database with same CATH homology
 5HQ8 A;  2ENZ A;  2L7X A;  3UGL A;  2JA1 A;  2N1A B;  1KBF A;  2SGQ I;  3RU0 A;  1PCE A;  1TBN A;  2LUY A;  2B8T A;  1DS2 I;  1KMA A;  2KMQ A;  5FUV A;  2WCY A;  1X4S A;  1OVO A;  5HI7 A;  2ELI A;  2FNF X;  1HDL A;  2QQD A;  1M8B A;  1YU6 C;  1BMO A;  1TOT A;  1TBR R;  1YTP A;  2GKT I;  1Y1B A;  4UXJ A;  5CCL A;  3OXG A;  2GKV A;  1CSO I;  3UGI A;  2SGD I;  2SGF I;  5FUW A;  1CE3 A;  1OMT A;  1R0R I;  1UVF A;  1IY5 A;  2OD1 A;  2JZM A;  1CT4 I;  2ROW A;  3UEJ A;  2NU1 I;  3UGD A;  2SGP I;  2UZ3 A;  1TIH A;  3UEY A;  2N17 A;  1M8C A;  2ERW A;  3PDN A;  2NU3 I;  5FUY A;  3VDP A;  1FAR A;  2KMP A;  1X74 A;  2JYY A;  1SGY I;  2DB6 A;  2ENN A;  1OMU A;  1CHO I;  4GI3 C;  3KY9 A;  2VRW B;  1HJA I;  1TBQ R;  2N71 A;  4B6D A;  2ODD A;  1SGD I;  5EX3 A;  1SGN I;  2V1C A;  1SGQ I;  2J9R A;  3B4V C;  1PJU A;  1Y8F A;  4L9M A;  2J87 A;  3E59 A;  1FAQ A;  2KMO A;  1XX6 A;  1SGP I;  2NU2 I;  1SGE I;  1KBE A;  2GKR I;  3VE5 A;  1BUS A;  2A20 A;  2CJS C;  2YQP A;  2P6A C;  5DAE A;  5EX0 A;  5FUX A;  1TGS I;  2KMR A;  1CGJ I;  1XA6 A;  4E1P A;  3TJQ A;  3CXL A;  3E2I A;  1PPF I;  1DS3 I;  1CT0 I;  4FKD A;  2L8E A;  1TBO A;  2ARP F;  3OXF A;  2V1C C;  1NUB A;  2BUS A;  1MT1 A;  2QQE A;  2JXD A;  1Z7K B;  4OVO A;  2QQ0 A;  4A24 A;  4E1R A;  1PTQ A;  2M5X A;  1UVG A;  1TUS A;  1U5K A;  1FYB A;  2NU0 I;  1LR8 A;  2ORW A;  1XBT A;  3GOX A;  1UUC A;  1R79 A;  2OVO A;  3OXL A;  3UFF A;  3FC3 A;  1V1H A;  1CT2 I;  2XRC A;  4SGB I;  3QTL D;  1H0Z A;  1HPT A;  3QWP A;  2NU4 I;  5JHW C;  2WVJ A;  1IW4 A;  4HGU A;  1RFH A;  4UXH A;  2QPO A;  2JW6 A;  2K9H A;  2N52 A;  5CCM A;  3HH2 C;  1CGI I;  2KCX A;  2F3C I;  2QQC A;  1IY6 A;  1OYV I;  2ORV A;  3OVO A;  1TUR A;  3VDU A;  1V1I A;  2E73 A;  3MEK A;  1LR7 A;  3SGB I;  1Y1C A;  1N13 A;  1W3S A;  3D00 A;  2B0U C;  1PTR A;  1VDD A;  4UXI A;  2W0T A;  1W4R A;  2GVI A;  3OL0 A;  2LEO A;  2E5R A;  2V53 A;  3SEK C;  1AN1 I;  2YUU A;  2DIP A;  2SGE I;  3SGQ I;  4JCV E;  1LR9 A;  3BJI A;  1SGR I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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