1UVFA

Solution structure of the structured part of the 15th domain of lekti
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
59
structure length
59
Chain Sequence
DSEMCKDYRVLPRIGYLCPKDLKPVCGDDGQTYNNPCMLCHENLIRQTNTHIRSTGKCE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Solution Structure of a Chimeric Lekti Domain Reveals a Chameleon Sequence
pubmed doi rcsb
molecule tags Serine proteinase inhibitor
source organism Homo sapiens
molecule keywords SERINE PROTEINASE INHIBITOR KAZAL TYPE 5
total genus 8
structure length 59
sequence length 59
ec nomenclature
pdb deposition date 2004-01-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1uvfA00
2KMPA 1TBQR 1FYBA 2SGFI 2KMRA 1UVGA 1CE3A 1PCEA 1SGRI 1Y1BA 2NU1I 1BUSA 1N13A 2B0UC 2NU0I 2QQDA 2GKTI 1CGII 2SGDI 1TBRR 4HGUA 2P6AC 2ERWA 2OVOA 1YTPA 1DS2I 1R0RI 1AN1I 1CT2I 1UVFA 1SGYI 2JZMA 1UUCA 1HPTA 1TURA 1BMOA 1PPFI 3SGQI 5JHWC 1OMTA 2SGQI 3TJQA 1IW4A 2XRCA 1OVOA 2N52A 1CSOI 2NU3I 2KMQA 2V53A 1OYVI 1IY5A 1CGJI 1YU6C 1CHOI 1TGSI 2BUSA 2NU2I 2N17A 2N71A 1H0ZA 2GKRI 1HDLA 3SGBI 1SGPI 1CT4I 5DAEA 2KMOA 1CT0I 2F3CI 3OVOA 1SGDI 1TIHA 2GKVA 1M8CA 1Z7KB 4GI3C 1OMUA 2KCXA 3SEKC 1LR7A 2JYYA 3QTLD 2SGEI 2NU4I 1SGEI 1Y1CA 1TUSA 1PJUA 2JXDA 4OVOA 1IY6A 1SGNI 3HH2C 1LR8A 1LR9A 2WCYA 1HJAI 1KMAA 1M8BA 4SGBI 2ARPF 2SGPI 3B4VC 1NUBA 1SGQI 2M5XA 2LEOA 1MT1A 1DS3I 2QQCA
chains in the Genus database with same CATH superfamily
2KMPA 2X3TA 3RU0A 1TBQR 4UXJA 3UEYA 5FUXA 1FYBA 2SGFI 3BJIA 3R5DA 2OU2A 3TO6A 2RC4A 2KMRA 2WGCA 3QWPA 1UVGA 1WGCA 5HQ8A 2VRWB 1PCEA 5E3PA 1CE3A 1SGRI 1Y1BA 2NU1I 3D00A 3GOXA 1BUSA 4L9MA 5E3QA 3OXFA 5CCLA 1N13A 2B0UC 2E73A 2NU0I 2QQDA 3R5CA 3UFFA 3MEKA 2GKTI 2QQ0A 1CGII 3FSYA 3OXGA 1XBTA 2E5RA 1MJAA 1XA6A 2SGDI 1V1IA 1TBRR 1WKXA 4HGUA 4E1RA 2P6AC 2ERWA 5CCMA 4AMLA 5FUVA 2OVOA 1YTPA 4E1PA 1DS2I 3E59A 3FC3A 1R0RI 1AN1I 1CT2I 1UVFA 2K9HA 1SGYI 3OL0A 1ULNA 1UUCA 2JZMA 3E2IA 1HPTA 1TURA 2UZ3A 5FUWA 3UGIA 3VE5A 1NXUA 1ULMA 3TOAA 1BMOA 2W0TA 2ENZA 1PPFI 3TO7A 1V1HA 1FARA 2ELIA 4MPIA 2L8EA 3SGQI 5JHWC 1OMTA 2SGQI 2QQEA 2CWFA 3FSXA 4FKDA 3TJQA 1KBEA 1RFHA 1X74A 2A20A 1IW4A 1WGTA 2XRCA 5E3RA 1OVOA 2PQ8A 2YUUA 1U5KA 1P9GA 2N52A 2GVIA 1CSOI 1K7UA 1XX6A 3OXLA 2LB7A 3VDUA 3PDNA 1FAQA 2NU3I 2KMQA 2RIJA 5HI7A 4UXIA 5EX3A 1UHAA 2FNFX 2V53A 4B6DA 2JW6A 1OYVI 1IY5A 3R5AA 1CGJI 1YU6C 1CHOI 1TGSI 3TO9A 3UEJA 2OD1A 1KBFA 2BUSA 2V1CC 2NU2I 2N17A 1W4RA 2JA1A 1Y8FA 2N71A 1H0ZA 1K7VA 2GKRI 1TOTA 5EX0A 3SGBI 3TOBA 1ULKA 1HDLA 9WGAA 1WTJA 1SGPI 3CXLA 1CT4I 4A24A 5DAEA 1PTQA 2OZUA 2DIPA 2KMOA 1CT0I 1W3SA 2F3CI 3OVOA 2DKVA 1SGDI 2WVJA 1TIHA 2CJSC 1PTRA 2GKVA 1M8CA 1Z7KB 3UGDA 2QPOA 2YQPA 4GI3C 3UGLA 1OMUA 2KCXA 3SEKC 1LR7A 2JYYA 3QTLD 1MJBA 1R79A 2J9RA 5J8FA 3R5BA 2SGEI 1K7TA 2NU4I 2ORWA 3UOEA 2V1CA 1P9ZA 1SGEI 2B8TA 1Y1CA 1HEVA 1TUSA 1PJUA 2JXDA 4OVOA 2ODDA 7WGAA 2ROWA 2UVOA 1IY6A 2CWHA 1SGNI 1X4SA 2CWGA 1MJ9A 3HH2C 5FUYA 2J87A 2ORVA 1LR8A 1LR9A 1S20A 2WCYA 1Z2IA 1HJAI 2L7XA 1M8BA 1KMAA 1TBOA 3VDPA 4SGBI 4WP4A 2ARPF 3KY9A 4UXHA 2ENNA 2Y0MA 2GIVA 2SGPI 4JCVE 5J8CA 1FY7A 2DB6A 3B4VC 3QAHA 2LUYA 4DNCA 1NUBA 1TBNA 1SGQI 2M5XA 2LEOA 2N1AB 1Q9BA 1MT1A 1VDDA 1DS3I 2X52A 2QQCA
chains in the Genus database with same CATH topology
2KMPA 3RU0A 1TBQR 4UXJA 3UEYA 5FUXA 1FYBA 2SGFI 3BJIA 2KMRA 3QWPA 5HQ8A 1UVGA 1CE3A 2VRWB 1PCEA 1SGRI 1Y1BA 2NU1I 3D00A 3GOXA 1BUSA 3OXFA 5CCLA 1N13A 2B0UC 2E73A 2NU0I 2QQDA 3UFFA 3MEKA 2GKTI 2QQ0A 1CGII 3OXGA 1XBTA 2E5RA 1XA6A 2SGDI 1V1IA 1TBRR 4HGUA 4E1RA 2P6AC 2ERWA 5CCMA 5FUVA 2OVOA 1YTPA 4E1PA 1DS2I 3E59A 3FC3A 1R0RI 1AN1I 1CT2I 1UVFA 2K9HA 1SGYI 3OL0A 2JZMA 1UUCA 3E2IA 3UGIA 1HPTA 1TURA 2UZ3A 5FUWA 3VE5A 1BMOA 2W0TA 2ENZA 1PPFI 1V1HA 1FARA 2ELIA 3SGQI 2L8EA 5JHWC 1OMTA 2SGQI 2QQEA 3TJQA 4FKDA 1KBEA 1RFHA 1X74A 2A20A 1IW4A 2XRCA 1OVOA 2YUUA 1U5KA 2N52A 2GVIA 1CSOI 1XX6A 3OXLA 3VDUA 3PDNA 1FAQA 2NU3I 2KMQA 5HI7A 4UXIA 5EX3A 2FNFX 2V53A 4B6DA 2JW6A 1OYVI 1IY5A 1CGJI 1YU6C 1CHOI 1TGSI 3UEJA 2OD1A 1KBFA 2BUSA 2V1CC 2NU2I 2N17A 1W4RA 2JA1A 1Y8FA 2N71A 1H0ZA 2GKRI 1TOTA 5EX0A 3SGBI 1HDLA 4A24A 1SGPI 3CXLA 1CT4I 5DAEA 1PTQA 2DIPA 2KMOA 1CT0I 1W3SA 2F3CI 3OVOA 1SGDI 2WVJA 1TIHA 2CJSC 1PTRA 2GKVA 1M8CA 1Z7KB 3UGDA 2QPOA 2YQPA 4GI3C 3UGLA 1OMUA 2KCXA 3SEKC 1LR7A 2JYYA 3QTLD 1R79A 2J9RA 2SGEI 2NU4I 2ORWA 2V1CA 1SGEI 2B8TA 1Y1CA 1TUSA 1PJUA 2JXDA 4OVOA 2ODDA 1IY6A 2ROWA 1SGNI 1X4SA 3HH2C 5FUYA 2J87A 2ORVA 1LR8A 1LR9A 2WCYA 1HJAI 2L7XA 1M8BA 1KMAA 1TBOA 3VDPA 4SGBI 2ARPF 3KY9A 4UXHA 2ENNA 4JCVE 2SGPI 2DB6A 3B4VC 2LUYA 1NUBA 1TBNA 1SGQI 2M5XA 2LEOA 2N1AB 4L9MA 1MT1A 1VDDA 1DS3I 2QQCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KMP A;  1TBQ R;  1FYB A;  2SGF I;  2KMR A;  1UVG A;  1CE3 A;  1PCE A;  1SGR I;  1Y1B A;  2NU1 I;  1BUS A;  1N13 A;  2B0U C;  2NU0 I;  2QQD A;  2GKT I;  1CGI I;  2SGD I;  1TBR R;  4HGU A;  2P6A C;  2ERW A;  2OVO A;  1YTP A;  1DS2 I;  1R0R I;  1AN1 I;  1CT2 I;  1UVF A;  1SGY I;  2JZM A;  1UUC A;  1HPT A;  1TUR A;  1BMO A;  1PPF I;  3SGQ I;  5JHW C;  1OMT A;  2SGQ I;  3TJQ A;  1IW4 A;  2XRC A;  1OVO A;  2N52 A;  1CSO I;  2NU3 I;  2KMQ A;  2V53 A;  1OYV I;  1IY5 A;  1CGJ I;  1YU6 C;  1CHO I;  1TGS I;  2BUS A;  2NU2 I;  2N17 A;  2N71 A;  1H0Z A;  2GKR I;  1HDL A;  3SGB I;  1SGP I;  1CT4 I;  5DAE A;  2KMO A;  1CT0 I;  2F3C I;  3OVO A;  1SGD I;  1TIH A;  2GKV A;  1M8C A;  1Z7K B;  4GI3 C;  1OMU A;  2KCX A;  3SEK C;  1LR7 A;  2JYY A;  3QTL D;  2SGE I;  2NU4 I;  1SGE I;  1Y1C A;  1TUS A;  1PJU A;  2JXD A;  4OVO A;  1IY6 A;  1SGN I;  3HH2 C;  1LR8 A;  1LR9 A;  2WCY A;  1HJA I;  1KMA A;  1M8B A;  4SGB I;  2ARP F;  2SGP I;  3B4V C;  1NUB A;  1SGQ I;  2M5X A;  2LEO A;  1MT1 A;  1DS3 I;  2QQC A; 
#chains in the Genus database with same CATH topology
 2KMP A;  2X3T A;  3RU0 A;  1TBQ R;  4UXJ A;  3UEY A;  5FUX A;  1FYB A;  2SGF I;  3BJI A;  3R5D A;  2OU2 A;  3TO6 A;  2RC4 A;  2KMR A;  2WGC A;  3QWP A;  1UVG A;  1WGC A;  5HQ8 A;  2VRW B;  1PCE A;  5E3P A;  1CE3 A;  1SGR I;  1Y1B A;  2NU1 I;  3D00 A;  3GOX A;  1BUS A;  4L9M A;  5E3Q A;  3OXF A;  5CCL A;  1N13 A;  2B0U C;  2E73 A;  2NU0 I;  2QQD A;  3R5C A;  3UFF A;  3MEK A;  2GKT I;  2QQ0 A;  1CGI I;  3FSY A;  3OXG A;  1XBT A;  2E5R A;  1MJA A;  1XA6 A;  2SGD I;  1V1I A;  1TBR R;  1WKX A;  4HGU A;  4E1R A;  2P6A C;  2ERW A;  5CCM A;  4AML A;  5FUV A;  2OVO A;  1YTP A;  4E1P A;  1DS2 I;  3E59 A;  3FC3 A;  1R0R I;  1AN1 I;  1CT2 I;  1UVF A;  2K9H A;  1SGY I;  3OL0 A;  1ULN A;  1UUC A;  2JZM A;  3E2I A;  1HPT A;  1TUR A;  2UZ3 A;  5FUW A;  3UGI A;  3VE5 A;  1NXU A;  1ULM A;  3TOA A;  1BMO A;  2W0T A;  2ENZ A;  1PPF I;  3TO7 A;  1V1H A;  1FAR A;  2ELI A;  4MPI A;  2L8E A;  3SGQ I;  5JHW C;  1OMT A;  2SGQ I;  2QQE A;  2CWF A;  3FSX A;  4FKD A;  3TJQ A;  1KBE A;  1RFH A;  1X74 A;  2A20 A;  1IW4 A;  1WGT A;  2XRC A;  5E3R A;  1OVO A;  2PQ8 A;  2YUU A;  1U5K A;  1P9G A;  2N52 A;  2GVI A;  1CSO I;  1K7U A;  1XX6 A;  3OXL A;  2LB7 A;  3VDU A;  3PDN A;  1FAQ A;  2NU3 I;  2KMQ A;  2RIJ A;  5HI7 A;  4UXI A;  5EX3 A;  1UHA A;  2FNF X;  2V53 A;  4B6D A;  2JW6 A;  1OYV I;  1IY5 A;  3R5A A;  1CGJ I;  1YU6 C;  1CHO I;  1TGS I;  3TO9 A;  3UEJ A;  2OD1 A;  1KBF A;  2BUS A;  2V1C C;  2NU2 I;  2N17 A;  1W4R A;  2JA1 A;  1Y8F A;  2N71 A;  1H0Z A;  1K7V A;  2GKR I;  1TOT A;  5EX0 A;  3SGB I;  3TOB A;  1ULK A;  1HDL A;  9WGA A;  1WTJ A;  1SGP I;  3CXL A;  1CT4 I;  4A24 A;  5DAE A;  1PTQ A;  2OZU A;  2DIP A;  2KMO A;  1CT0 I;  1W3S A;  2F3C I;  3OVO A;  2DKV A;  1SGD I;  2WVJ A;  1TIH A;  2CJS C;  1PTR A;  2GKV A;  1M8C A;  1Z7K B;  3UGD A;  2QPO A;  2YQP A;  4GI3 C;  3UGL A;  1OMU A;  2KCX A;  3SEK C;  1LR7 A;  2JYY A;  3QTL D;  1MJB A;  1R79 A;  2J9R A;  5J8F A;  3R5B A;  2SGE I;  1K7T A;  2NU4 I;  2ORW A;  3UOE A;  2V1C A;  1P9Z A;  1SGE I;  2B8T A;  1Y1C A;  1HEV A;  1TUS A;  1PJU A;  2JXD A;  4OVO A;  2ODD A;  7WGA A;  2ROW A;  2UVO A;  1IY6 A;  2CWH A;  1SGN I;  1X4S A;  2CWG A;  1MJ9 A;  3HH2 C;  5FUY A;  2J87 A;  2ORV A;  1LR8 A;  1LR9 A;  1S20 A;  2WCY A;  1Z2I A;  1HJA I;  2L7X A;  1M8B A;  1KMA A;  1TBO A;  3VDP A;  4SGB I;  4WP4 A;  2ARP F;  3KY9 A;  4UXH A;  2ENN A;  2Y0M A;  2GIV A;  2SGP I;  4JCV E;  5J8C A;  1FY7 A;  2DB6 A;  3B4V C;  3QAH A;  2LUY A;  4DNC A;  1NUB A;  1TBN A;  1SGQ I;  2M5X A;  2LEO A;  2N1A B;  1Q9B A;  1MT1 A;  1VDD A;  1DS3 I;  2X52 A;  2QQC A; 
#chains in the Genus database with same CATH homology
 2KMP A;  3RU0 A;  1TBQ R;  4UXJ A;  3UEY A;  5FUX A;  1FYB A;  2SGF I;  3BJI A;  2KMR A;  3QWP A;  5HQ8 A;  1UVG A;  1CE3 A;  2VRW B;  1PCE A;  1SGR I;  1Y1B A;  2NU1 I;  3D00 A;  3GOX A;  1BUS A;  3OXF A;  5CCL A;  1N13 A;  2B0U C;  2E73 A;  2NU0 I;  2QQD A;  3UFF A;  3MEK A;  2GKT I;  2QQ0 A;  1CGI I;  3OXG A;  1XBT A;  2E5R A;  1XA6 A;  2SGD I;  1V1I A;  1TBR R;  4HGU A;  4E1R A;  2P6A C;  2ERW A;  5CCM A;  5FUV A;  2OVO A;  1YTP A;  4E1P A;  1DS2 I;  3E59 A;  3FC3 A;  1R0R I;  1AN1 I;  1CT2 I;  1UVF A;  2K9H A;  1SGY I;  3OL0 A;  2JZM A;  1UUC A;  3E2I A;  3UGI A;  1HPT A;  1TUR A;  2UZ3 A;  5FUW A;  3VE5 A;  1BMO A;  2W0T A;  2ENZ A;  1PPF I;  1V1H A;  1FAR A;  2ELI A;  3SGQ I;  2L8E A;  5JHW C;  1OMT A;  2SGQ I;  2QQE A;  3TJQ A;  4FKD A;  1KBE A;  1RFH A;  1X74 A;  2A20 A;  1IW4 A;  2XRC A;  1OVO A;  2YUU A;  1U5K A;  2N52 A;  2GVI A;  1CSO I;  1XX6 A;  3OXL A;  3VDU A;  3PDN A;  1FAQ A;  2NU3 I;  2KMQ A;  5HI7 A;  4UXI A;  5EX3 A;  2FNF X;  2V53 A;  4B6D A;  2JW6 A;  1OYV I;  1IY5 A;  1CGJ I;  1YU6 C;  1CHO I;  1TGS I;  3UEJ A;  2OD1 A;  1KBF A;  2BUS A;  2V1C C;  2NU2 I;  2N17 A;  1W4R A;  2JA1 A;  1Y8F A;  2N71 A;  1H0Z A;  2GKR I;  1TOT A;  5EX0 A;  3SGB I;  1HDL A;  4A24 A;  1SGP I;  3CXL A;  1CT4 I;  5DAE A;  1PTQ A;  2DIP A;  2KMO A;  1CT0 I;  1W3S A;  2F3C I;  3OVO A;  1SGD I;  2WVJ A;  1TIH A;  2CJS C;  1PTR A;  2GKV A;  1M8C A;  1Z7K B;  3UGD A;  2QPO A;  2YQP A;  4GI3 C;  3UGL A;  1OMU A;  2KCX A;  3SEK C;  1LR7 A;  2JYY A;  3QTL D;  1R79 A;  2J9R A;  2SGE I;  2NU4 I;  2ORW A;  2V1C A;  1SGE I;  2B8T A;  1Y1C A;  1TUS A;  1PJU A;  2JXD A;  4OVO A;  2ODD A;  1IY6 A;  2ROW A;  1SGN I;  1X4S A;  3HH2 C;  5FUY A;  2J87 A;  2ORV A;  1LR8 A;  1LR9 A;  2WCY A;  1HJA I;  2L7X A;  1M8B A;  1KMA A;  1TBO A;  3VDP A;  4SGB I;  2ARP F;  3KY9 A;  4UXH A;  2ENN A;  4JCV E;  2SGP I;  2DB6 A;  3B4V C;  2LUY A;  1NUB A;  1TBN A;  1SGQ I;  2M5X A;  2LEO A;  2N1A B;  4L9M A;  1MT1 A;  1VDD A;  1DS3 I;  2QQC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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