1UVGA

Solution structure of the 15th domain of lekti
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
76
structure length
76
Chain Sequence
DSEMCKDYRVLPRIGYLCPKDLKPVCGDDGQTYNNPCMLCHENLIRQTNTHIRSTGKCEESSTPGTTAASMPPSDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Solution Structure of a Chimeric Lekti Domain Reveals a Chameleon Sequence
pubmed doi rcsb
molecule tags Serine proteinase inhibitor
source organism Homo sapiens
molecule keywords SERINE PROTEINASE INHIBITOR KAZAL TYPE 5
total genus 11
structure length 76
sequence length 76
ec nomenclature
pdb deposition date 2004-01-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1uvgA01
1CT4I 5JHWC 1SGPI 2NU3I 1NUBA 1TBRR 1N13A 1CE3A 1CGJI 1BUSA 2P6AC 1PCEA 2JZMA 1MT1A 1AN1I 3HH2C 1TIHA 1R0RI 2KMOA 1YU6C 1HPTA 2GKVA 5DAEA 1CHOI 1IW4A 2NU2I 2XRCA 1OYVI 1UVFA 1HDLA 2NU1I 1UVGA 2N71A 1SGDI 1DS3I 1TBQR 1SGRI 2ARPF 1M8CA 1OMUA 1Y1BA 1CT2I 1LR9A 1UUCA 2KCXA 2SGEI 1IY6A 2KMRA 2V53A 1SGNI 1CGII 1M8BA 1DS2I 3SGQI 2SGFI 4HGUA 1TURA 2SGQI 2SGPI 1KMAA 2B0UC 1YTPA 1LR7A 1Z7KB 1CT0I 2M5XA 1PJUA 2NU4I 2N52A 4OVOA 3SEKC 2N17A 4GI3C 2BUSA 1H0ZA 1SGEI 3OVOA 2JYYA 2WCYA 2SGDI 1HJAI 1PPFI 2QQCA 2KMPA 2NU0I 3SGBI 2GKRI 1OMTA 2F3CI 2QQDA 1FYBA 1BMOA 4SGBI 2JXDA 3QTLD 2GKTI 1SGYI 2KMQA 1CSOI 1LR8A 3B4VC 1TGSI 1SGQI 1Y1CA 2LEOA 2OVOA 1OVOA 2ERWA 1IY5A 3TJQA 1TUSA
chains in the Genus database with same CATH superfamily
1CT4I 1FAQA 5JHWC 1SGPI 1FARA 1ULKA 2NU3I 4JCVE 3UGDA 3UEJA 2YUUA 1NUBA 1TBRR 2UZ3A 2YQPA 5EX3A 1N13A 1TBOA 3R5BA 1CE3A 1CGJI 2X52A 1BUSA 2QQEA 2P6AC 1WGTA 3KY9A 4B6DA 1PCEA 1XX6A 3UGLA 1WGCA 3UEYA 5FUYA 2L7XA 2ENZA 3QWPA 2FNFX 2JZMA 1WTJA 4UXHA 1MT1A 1AN1I 3HH2C 3UOEA 2WVJA 1TIHA 5EX0A 1R0RI 5J8FA 2KMOA 2ENNA 3VDUA 3GOXA 1NXUA 1YU6C 1HPTA 2GKVA 5DAEA 1CHOI 5FUWA 3TO9A 1MJ9A 2NU2I 2XRCA 3D00A 5E3PA 5E3RA 1OYVI 1UVFA 1XBTA 2GVIA 2VRWB 2NU1I 1HDLA 3R5AA 3TO7A 1UVGA 2N71A 2OD1A 2CJSC 2QPOA 2Y0MA 1SGDI 3E2IA 3PDNA 2E5RA 3UFFA 3OXLA 2CWHA 2ORVA 1DS3I 1TBQR 1SGRI 3OXFA 4AMLA 3VE5A 2ARPF 2ELIA 1RFHA 3TO6A 1M8CA 1K7TA 1OMUA 5HI7A 1R79A 1Y1BA 2RC4A 1CT2I 1LR9A 1UUCA 2N1AB 2RIJA 2KCXA 2UVOA 1TBNA 2ROWA 3CXLA 5J8CA 3FC3A 3FSXA 2SGEI 1IY6A 1HEVA 2J87A 2KMRA 2E73A 4UXJA 2V53A 1SGNI 1CGII 2DIPA 3FSYA 3VDPA 4UXIA 1M8BA 1DS2I 3SGQI 1S20A 2ORWA 1MJAA 1ULMA 2SGFI 3TOAA 4DNCA 2ODDA 1X4SA 1XA6A 4HGUA 2CWFA 2V1CC 3R5DA 2WGCA 1TURA 3RU0A 3TOBA 2LUYA 1V1HA 2SGQI 5E3QA 5HQ8A 3R5CA 2SGPI 1KMAA 2B0UC 1YTPA 2QQ0A 2DB6A 4E1PA 3BJIA 2JW6A 3MEKA 2X3TA 1Z2IA 1LR7A 1Z7KB 2DKVA 3OL0A 5CCMA 1WKXA 1CT0I 1P9GA 1PJUA 2M5XA 2NU4I 2N52A 3E59A 4OVOA 2A20A 3SEKC 1PTRA 3UGIA 1V1IA 2N17A 4GI3C 4L9MA 4A24A 1Q9BA 2BUSA 1H0ZA 2K9HA 1SGEI 3OVOA 1U5KA 2JYYA 2WCYA 2SGDI 1HJAI 1Y8FA 9WGAA 1IW4A 2B8TA 1PPFI 2J9RA 2QQCA 1X74A 2KMPA 1K7UA 2JA1A 2NU0I 3SGBI 2GKRI 1OMTA 2LB7A 2PQ8A 2V1CA 2F3CI 1TOTA 2QQDA 2OU2A 4FKDA 1FYBA 1BMOA 4E1RA 4SGBI 1MJBA 2JXDA 1K7VA 3QTLD 1P9ZA 1SGYI 2GKTI 5FUVA 5FUXA 2L8EA 2KMQA 1CSOI 2OZUA 1KBEA 1LR8A 3B4VC 1TGSI 1SGQI 2GIVA 2CWGA 2W0TA 4WP4A 1Y1CA 1ULNA 3OXGA 2LEOA 1FY7A 5CCLA 1W4RA 1KBFA 1W3SA 2OVOA 4MPIA 1OVOA 2ERWA 1IY5A 3TJQA 1VDDA 1UHAA 3QAHA 7WGAA 1PTQA 1TUSA
chains in the Genus database with same CATH topology
1CT4I 1FAQA 5JHWC 1SGPI 1FARA 2NU3I 4JCVE 3UGDA 3UEJA 2YUUA 1NUBA 1TBRR 2UZ3A 2YQPA 5EX3A 1N13A 1TBOA 1CE3A 1CGJI 1BUSA 2QQEA 2P6AC 3KY9A 4B6DA 1PCEA 1XX6A 3UGLA 3UEYA 5FUYA 2L7XA 2ENZA 3QWPA 2FNFX 2JZMA 4UXHA 1MT1A 1AN1I 3HH2C 2WVJA 1TIHA 5EX0A 1R0RI 2KMOA 2ENNA 3VDUA 3GOXA 1YU6C 1HPTA 2GKVA 5DAEA 1CHOI 5FUWA 1IW4A 2NU2I 2XRCA 3D00A 1OYVI 1UVFA 1XBTA 2GVIA 2VRWB 2NU1I 1HDLA 1UVGA 2N71A 2OD1A 2CJSC 2QPOA 1SGDI 3E2IA 3PDNA 2E5RA 3UFFA 3OXLA 2ORVA 1DS3I 1TBQR 1SGRI 3OXFA 3VE5A 2ARPF 2ELIA 1RFHA 1M8CA 1OMUA 5HI7A 1R79A 1Y1BA 1CT2I 1LR9A 1UUCA 2N1AB 3CXLA 2KCXA 3FC3A 1TBNA 2ROWA 2SGEI 1IY6A 2J87A 2KMRA 2E73A 4UXJA 2V53A 1SGNI 1CGII 2DIPA 3VDPA 4UXIA 1M8BA 1DS2I 3SGQI 2ORWA 2SGFI 2ODDA 1X4SA 1XA6A 4HGUA 2V1CC 1TURA 3RU0A 2LUYA 1V1HA 2SGQI 5HQ8A 2SGPI 1KMAA 2B0UC 1YTPA 2QQ0A 2DB6A 4E1PA 3BJIA 2JW6A 3MEKA 1LR7A 1Z7KB 3OL0A 5CCMA 1CT0I 2M5XA 1PJUA 2NU4I 3E59A 2N52A 4OVOA 3UGIA 2A20A 3SEKC 1PTRA 1V1IA 2N17A 4GI3C 4L9MA 4A24A 2BUSA 1H0ZA 2K9HA 1SGEI 3OVOA 1U5KA 2JYYA 2WCYA 2SGDI 1HJAI 1Y8FA 2B8TA 1PPFI 2J9RA 2QQCA 1X74A 2KMPA 2JA1A 2NU0I 3SGBI 2GKRI 1OMTA 2V1CA 2F3CI 1TOTA 2QQDA 4FKDA 1FYBA 1BMOA 4E1RA 4SGBI 2JXDA 3QTLD 2GKTI 1SGYI 5FUVA 5FUXA 2L8EA 2KMQA 1CSOI 1KBEA 1LR8A 3B4VC 1TGSI 1SGQI 2W0TA 1KBFA 1Y1CA 3OXGA 2LEOA 5CCLA 1W4RA 1W3SA 2OVOA 1OVOA 2ERWA 1IY5A 3TJQA 1VDDA 1PTQA 1TUSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CT4 I;  5JHW C;  1SGP I;  2NU3 I;  1NUB A;  1TBR R;  1N13 A;  1CE3 A;  1CGJ I;  1BUS A;  2P6A C;  1PCE A;  2JZM A;  1MT1 A;  1AN1 I;  3HH2 C;  1TIH A;  1R0R I;  2KMO A;  1YU6 C;  1HPT A;  2GKV A;  5DAE A;  1CHO I;  1IW4 A;  2NU2 I;  2XRC A;  1OYV I;  1UVF A;  1HDL A;  2NU1 I;  1UVG A;  2N71 A;  1SGD I;  1DS3 I;  1TBQ R;  1SGR I;  2ARP F;  1M8C A;  1OMU A;  1Y1B A;  1CT2 I;  1LR9 A;  1UUC A;  2KCX A;  2SGE I;  1IY6 A;  2KMR A;  2V53 A;  1SGN I;  1CGI I;  1M8B A;  1DS2 I;  3SGQ I;  2SGF I;  4HGU A;  1TUR A;  2SGQ I;  2SGP I;  1KMA A;  2B0U C;  1YTP A;  1LR7 A;  1Z7K B;  1CT0 I;  2M5X A;  1PJU A;  2NU4 I;  2N52 A;  4OVO A;  3SEK C;  2N17 A;  4GI3 C;  2BUS A;  1H0Z A;  1SGE I;  3OVO A;  2JYY A;  2WCY A;  2SGD I;  1HJA I;  1PPF I;  2QQC A;  2KMP A;  2NU0 I;  3SGB I;  2GKR I;  1OMT A;  2F3C I;  2QQD A;  1FYB A;  1BMO A;  4SGB I;  2JXD A;  3QTL D;  2GKT I;  1SGY I;  2KMQ A;  1CSO I;  1LR8 A;  3B4V C;  1TGS I;  1SGQ I;  1Y1C A;  2LEO A;  2OVO A;  1OVO A;  2ERW A;  1IY5 A;  3TJQ A;  1TUS A; 
#chains in the Genus database with same CATH topology
 1CT4 I;  1FAQ A;  5JHW C;  1SGP I;  1FAR A;  1ULK A;  2NU3 I;  4JCV E;  3UGD A;  3UEJ A;  2YUU A;  1NUB A;  1TBR R;  2UZ3 A;  2YQP A;  5EX3 A;  1N13 A;  1TBO A;  3R5B A;  1CE3 A;  1CGJ I;  2X52 A;  1BUS A;  2QQE A;  2P6A C;  1WGT A;  3KY9 A;  4B6D A;  1PCE A;  1XX6 A;  3UGL A;  1WGC A;  3UEY A;  5FUY A;  2L7X A;  2ENZ A;  3QWP A;  2FNF X;  2JZM A;  1WTJ A;  4UXH A;  1MT1 A;  1AN1 I;  3HH2 C;  3UOE A;  2WVJ A;  1TIH A;  5EX0 A;  1R0R I;  5J8F A;  2KMO A;  2ENN A;  3VDU A;  3GOX A;  1NXU A;  1YU6 C;  1HPT A;  2GKV A;  5DAE A;  1CHO I;  5FUW A;  3TO9 A;  1MJ9 A;  2NU2 I;  2XRC A;  3D00 A;  5E3P A;  5E3R A;  1OYV I;  1UVF A;  1XBT A;  2GVI A;  2VRW B;  2NU1 I;  1HDL A;  3R5A A;  3TO7 A;  1UVG A;  2N71 A;  2OD1 A;  2CJS C;  2QPO A;  2Y0M A;  1SGD I;  3E2I A;  3PDN A;  2E5R A;  3UFF A;  3OXL A;  2CWH A;  2ORV A;  1DS3 I;  1TBQ R;  1SGR I;  3OXF A;  4AML A;  3VE5 A;  2ARP F;  2ELI A;  1RFH A;  3TO6 A;  1M8C A;  1K7T A;  1OMU A;  5HI7 A;  1R79 A;  1Y1B A;  2RC4 A;  1CT2 I;  1LR9 A;  1UUC A;  2N1A B;  2RIJ A;  2KCX A;  2UVO A;  1TBN A;  2ROW A;  3CXL A;  5J8C A;  3FC3 A;  3FSX A;  2SGE I;  1IY6 A;  1HEV A;  2J87 A;  2KMR A;  2E73 A;  4UXJ A;  2V53 A;  1SGN I;  1CGI I;  2DIP A;  3FSY A;  3VDP A;  4UXI A;  1M8B A;  1DS2 I;  3SGQ I;  1S20 A;  2ORW A;  1MJA A;  1ULM A;  2SGF I;  3TOA A;  4DNC A;  2ODD A;  1X4S A;  1XA6 A;  4HGU A;  2CWF A;  2V1C C;  3R5D A;  2WGC A;  1TUR A;  3RU0 A;  3TOB A;  2LUY A;  1V1H A;  2SGQ I;  5E3Q A;  5HQ8 A;  3R5C A;  2SGP I;  1KMA A;  2B0U C;  1YTP A;  2QQ0 A;  2DB6 A;  4E1P A;  3BJI A;  2JW6 A;  3MEK A;  2X3T A;  1Z2I A;  1LR7 A;  1Z7K B;  2DKV A;  3OL0 A;  5CCM A;  1WKX A;  1CT0 I;  1P9G A;  1PJU A;  2M5X A;  2NU4 I;  2N52 A;  3E59 A;  4OVO A;  2A20 A;  3SEK C;  1PTR A;  3UGI A;  1V1I A;  2N17 A;  4GI3 C;  4L9M A;  4A24 A;  1Q9B A;  2BUS A;  1H0Z A;  2K9H A;  1SGE I;  3OVO A;  1U5K A;  2JYY A;  2WCY A;  2SGD I;  1HJA I;  1Y8F A;  9WGA A;  1IW4 A;  2B8T A;  1PPF I;  2J9R A;  2QQC A;  1X74 A;  2KMP A;  1K7U A;  2JA1 A;  2NU0 I;  3SGB I;  2GKR I;  1OMT A;  2LB7 A;  2PQ8 A;  2V1C A;  2F3C I;  1TOT A;  2QQD A;  2OU2 A;  4FKD A;  1FYB A;  1BMO A;  4E1R A;  4SGB I;  1MJB A;  2JXD A;  1K7V A;  3QTL D;  1P9Z A;  1SGY I;  2GKT I;  5FUV A;  5FUX A;  2L8E A;  2KMQ A;  1CSO I;  2OZU A;  1KBE A;  1LR8 A;  3B4V C;  1TGS I;  1SGQ I;  2GIV A;  2CWG A;  2W0T A;  4WP4 A;  1Y1C A;  1ULN A;  3OXG A;  2LEO A;  1FY7 A;  5CCL A;  1W4R A;  1KBF A;  1W3S A;  2OVO A;  4MPI A;  1OVO A;  2ERW A;  1IY5 A;  3TJQ A;  1VDD A;  1UHA A;  3QAH A;  7WGA A;  1PTQ A;  1TUS A; 
#chains in the Genus database with same CATH homology
 1CT4 I;  1FAQ A;  5JHW C;  1SGP I;  1FAR A;  2NU3 I;  4JCV E;  3UGD A;  3UEJ A;  2YUU A;  1NUB A;  1TBR R;  2UZ3 A;  2YQP A;  5EX3 A;  1N13 A;  1TBO A;  1CE3 A;  1CGJ I;  1BUS A;  2QQE A;  2P6A C;  3KY9 A;  4B6D A;  1PCE A;  1XX6 A;  3UGL A;  3UEY A;  5FUY A;  2L7X A;  2ENZ A;  3QWP A;  2FNF X;  2JZM A;  4UXH A;  1MT1 A;  1AN1 I;  3HH2 C;  2WVJ A;  1TIH A;  5EX0 A;  1R0R I;  2KMO A;  2ENN A;  3VDU A;  3GOX A;  1YU6 C;  1HPT A;  2GKV A;  5DAE A;  1CHO I;  5FUW A;  1IW4 A;  2NU2 I;  2XRC A;  3D00 A;  1OYV I;  1UVF A;  1XBT A;  2GVI A;  2VRW B;  2NU1 I;  1HDL A;  1UVG A;  2N71 A;  2OD1 A;  2CJS C;  2QPO A;  1SGD I;  3E2I A;  3PDN A;  2E5R A;  3UFF A;  3OXL A;  2ORV A;  1DS3 I;  1TBQ R;  1SGR I;  3OXF A;  3VE5 A;  2ARP F;  2ELI A;  1RFH A;  1M8C A;  1OMU A;  5HI7 A;  1R79 A;  1Y1B A;  1CT2 I;  1LR9 A;  1UUC A;  2N1A B;  3CXL A;  2KCX A;  3FC3 A;  1TBN A;  2ROW A;  2SGE I;  1IY6 A;  2J87 A;  2KMR A;  2E73 A;  4UXJ A;  2V53 A;  1SGN I;  1CGI I;  2DIP A;  3VDP A;  4UXI A;  1M8B A;  1DS2 I;  3SGQ I;  2ORW A;  2SGF I;  2ODD A;  1X4S A;  1XA6 A;  4HGU A;  2V1C C;  1TUR A;  3RU0 A;  2LUY A;  1V1H A;  2SGQ I;  5HQ8 A;  2SGP I;  1KMA A;  2B0U C;  1YTP A;  2QQ0 A;  2DB6 A;  4E1P A;  3BJI A;  2JW6 A;  3MEK A;  1LR7 A;  1Z7K B;  3OL0 A;  5CCM A;  1CT0 I;  2M5X A;  1PJU A;  2NU4 I;  3E59 A;  2N52 A;  4OVO A;  3UGI A;  2A20 A;  3SEK C;  1PTR A;  1V1I A;  2N17 A;  4GI3 C;  4L9M A;  4A24 A;  2BUS A;  1H0Z A;  2K9H A;  1SGE I;  3OVO A;  1U5K A;  2JYY A;  2WCY A;  2SGD I;  1HJA I;  1Y8F A;  2B8T A;  1PPF I;  2J9R A;  2QQC A;  1X74 A;  2KMP A;  2JA1 A;  2NU0 I;  3SGB I;  2GKR I;  1OMT A;  2V1C A;  2F3C I;  1TOT A;  2QQD A;  4FKD A;  1FYB A;  1BMO A;  4E1R A;  4SGB I;  2JXD A;  3QTL D;  2GKT I;  1SGY I;  5FUV A;  5FUX A;  2L8E A;  2KMQ A;  1CSO I;  1KBE A;  1LR8 A;  3B4V C;  1TGS I;  1SGQ I;  2W0T A;  1KBF A;  1Y1C A;  3OXG A;  2LEO A;  5CCL A;  1W4R A;  1W3S A;  2OVO A;  1OVO A;  2ERW A;  1IY5 A;  3TJQ A;  1VDD A;  1PTQ A;  1TUS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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