1Y8FA

Solution structure of the munc13-1 c1-domain
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
51
structure length
51
Chain Sequence
QHNFEVWTATTPTYCYECEGLLWGIARQGMRCTECGVKCHEKCQDLLNADC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Intramolecular occlusion of the diacylglycerol-binding site in the C1 domain of munc13-1.
pubmed doi rcsb
molecule tags Endocytosis/exocytosis,signaling protein
source organism Rattus norvegicus
molecule keywords Unc-13 homolog A
total genus 5
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 2004-12-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.20 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1y8fA00
2E73A 4B6DA 1Y8FA 1FAQA 1XX6A 2YUUA 2VRWB 4UXJA 2QPOA 2J87A 2ENZA 2WVJA 3BJIA 4L9MA 1KBEA 1KBFA 3UEJA 1PTRA 2DB6A 3UGDA 3E2IA 2ENNA 3CXLA 1TBNA 2JA1A 2ROWA 5FUXA 1PTQA 1XA6A 2ORWA 2ELIA 5FUVA 2UZ3A 1RFHA 3KY9A 5FUWA 1FARA 3UGIA 4UXHA 2FNFX 2GVIA 2B8TA 5FUYA 4UXIA 2J9RA 3UEYA 1W4RA 2QQ0A 3UGLA 3UFFA 2ORVA 1XBTA 2QQEA 4FKDA 1TBOA 1R79A
chains in the Genus database with same CATH superfamily
1FAQA 5CCLA 2RC4A 3TO6A 2KMOA 2QPOA 2ENZA 4L9MA 1CGII 1DS2I 2KMQA 5JHWC 1HDLA 1Z2IA 3OVOA 2DB6A 4JCVE 2P6AC 3UOEA 2JXDA 1S20A 1HJAI 2QQCA 3E2IA 5CCMA 3CXLA 3GOXA 1Y1BA 2WCYA 2DIPA 1OVOA 1XA6A 2ORWA 2OZUA 3HH2C 5E3PA 1UVGA 1DS3I 1X74A 2UZ3A 1UVFA 1V1HA 1FY7A 2L8EA 1SGQI 2W0TA 1TBQR 2N52A 3UGIA 2FNFX 5E3RA 1UHAA 2B8TA 3RU0A 2PQ8A 2B0UC 1SGDI 1W4RA 2QQ0A 1HPTA 1SGEI 2ODDA 3UEYA 1OMUA 3VDPA 3MEKA 2QQEA 1ULNA 1CT0I 2NU3I 1R79A 2JW6A 1Y8FA 1XX6A 2XRCA 1WGTA 2VRWB 4UXJA 2A20A 1KBEA 1CHOI 2SGFI 1W3SA 1ULKA 4DNCA 1BMOA 1TOTA 1TGSI 2GIVA 1YTPA 4MPIA 3TO7A 1TBNA 2OD1A 3OL0A 5FUXA 2RIJA 3SEKC 2CJSC 2UVOA 1R0RI 2SGDI 1MJBA 2YQPA 1FARA 1OMTA 1PCEA 1SGNI 2OVOA 1MT1A 2SGPI 2KMRA 2V53A 2NU4I 1BUSA 1CGJI 4WP4A 3R5AA 1Y1CA 3FC3A 3VE5A 1CT2I 1NXUA 1MJAA 1H0ZA 1P9ZA 2NU2I 5EX3A 2X3TA 3QAHA 3UFFA 5J8FA 4FKDA 3E59A 3TJQA 2M5XA 5J8CA 2E73A 1WKXA 2LB7A 2GKVA 3QWPA 2YUUA 3SGBI 1HEVA 2GKTI 2WVJA 3BJIA 3TO9A 2Y0MA 1N13A 2V1CC 1IW4A 5E3QA 3UEJA 1PTRA 1CT4I 3QTLD 2KMPA 4E1RA 2SGEI 1TURA 2N71A 1OYVI 2KCXA 3UGDA 1CSOI 1WGCA 1K7VA 1LR7A 2JA1A 1LR8A 2ROWA 2V1CA 4OVOA 7WGAA 1FYBA 5FUVA 1TIHA 2X52A 1RFHA 3KY9A 5FUWA 2SGQI 1Z7KB 1M8CA 1ULMA 2GVIA 3FSYA 1AN1I 1K7UA 4UXHA 1KMAA 5FUYA 2K9HA 2JZMA 3R5CA 4SGBI 2J9RA 5EX0A 3SGQI 3TOAA 3UGLA 5HQ8A 2N1AB 1TBRR 1UUCA 4GI3C 1SGPI 1TBOA 2L7XA 2GKRI 3FSXA 4A24A 1V1IA 1NUBA 1PPFI 1M8BA 1SGRI 2ARPF 2QQDA 2J87A 2LUYA 1LR9A 2N17A 3VDUA 1MJ9A 1KBFA 1Q9BA 3R5DA 1X4SA 2E5RA 1P9GA 2DKVA 9WGAA 1IY5A 2BUSA 3OXFA 2ENNA 2LEOA 2OU2A 1K7TA 2NU0I 4E1PA 1WTJA 1VDDA 2WGCA 1PTQA 4HGUA 3B4VC 2ELIA 1IY6A 3PDNA 1CE3A 3D00A 2CWGA 2CWFA 4AMLA 3TOBA 4UXIA 1YU6C 5DAEA 1SGYI 5HI7A 3OXGA 1PJUA 1TUSA 2F3CI 2JYYA 1XBTA 2CWHA 2ORVA 3OXLA 3R5BA 1U5KA 2NU1I 2ERWA 4B6DA
chains in the Genus database with same CATH topology
1FAQA 5CCLA 2KMOA 2QPOA 2ENZA 4L9MA 1CGII 1DS2I 2KMQA 5JHWC 1HDLA 3OVOA 2DB6A 4JCVE 2P6AC 2JXDA 2QQCA 1HJAI 3E2IA 5CCMA 3CXLA 3GOXA 1Y1BA 2WCYA 2DIPA 1OVOA 1XA6A 2ORWA 3HH2C 1UVGA 1DS3I 1X74A 2UZ3A 1UVFA 1V1HA 2L8EA 1SGQI 2W0TA 1TBQR 2N52A 3UGIA 2FNFX 2B8TA 3RU0A 2B0UC 1SGDI 1W4RA 2QQ0A 1HPTA 1SGEI 2ODDA 3UEYA 1OMUA 3VDPA 3MEKA 2QQEA 1CT0I 2NU3I 1R79A 2JW6A 1Y8FA 1XX6A 2XRCA 2VRWB 4UXJA 2A20A 1KBEA 1CHOI 2SGFI 1W3SA 1BMOA 1TOTA 1TGSI 1YTPA 1TBNA 2OD1A 3OL0A 5FUXA 3SEKC 2CJSC 1R0RI 2SGDI 2YQPA 1FARA 1OMTA 1PCEA 1SGNI 2OVOA 1MT1A 2SGPI 2KMRA 2V53A 2NU4I 1BUSA 1CGJI 3FC3A 1Y1CA 3VE5A 1CT2I 1H0ZA 2NU2I 5EX3A 3UFFA 4FKDA 3E59A 3TJQA 2M5XA 2E73A 2GKVA 3QWPA 2YUUA 3SGBI 2GKTI 2WVJA 3BJIA 1N13A 2V1CC 1IW4A 3UEJA 1PTRA 1CT4I 3QTLD 2KMPA 4E1RA 2SGEI 1TURA 2N71A 1OYVI 2KCXA 3UGDA 1CSOI 1LR7A 2JA1A 1LR8A 2ROWA 2V1CA 4OVOA 1FYBA 5FUVA 1TIHA 1RFHA 3KY9A 5FUWA 2SGQI 1Z7KB 1M8CA 4UXHA 2GVIA 1AN1I 1KMAA 5FUYA 2K9HA 2JZMA 4SGBI 5EX0A 2J9RA 3SGQI 5HQ8A 3UGLA 2N1AB 1TBRR 1UUCA 4GI3C 1SGPI 1TBOA 2L7XA 2GKRI 4A24A 1V1IA 1NUBA 1PPFI 1M8BA 1SGRI 2ARPF 2QQDA 2J87A 2LUYA 1LR9A 2N17A 3VDUA 1KBFA 1X4SA 2E5RA 1IY5A 2BUSA 3OXFA 2ENNA 2LEOA 4E1PA 2NU0I 1VDDA 1PTQA 4HGUA 3B4VC 2ELIA 1IY6A 3PDNA 1CE3A 3D00A 4UXIA 1YU6C 5DAEA 1SGYI 5HI7A 3OXGA 1PJUA 1TUSA 2F3CI 2JYYA 1XBTA 2ORVA 3OXLA 1U5KA 2NU1I 2ERWA 4B6DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E73 A;  4B6D A;  1Y8F A;  1FAQ A;  1XX6 A;  2YUU A;  2VRW B;  4UXJ A;  2QPO A;  2J87 A;  2ENZ A;  2WVJ A;  3BJI A;  4L9M A;  1KBE A;  1KBF A;  3UEJ A;  1PTR A;  2DB6 A;  3UGD A;  3E2I A;  2ENN A;  3CXL A;  1TBN A;  2JA1 A;  2ROW A;  5FUX A;  1PTQ A;  1XA6 A;  2ORW A;  2ELI A;  5FUV A;  2UZ3 A;  1RFH A;  3KY9 A;  5FUW A;  1FAR A;  3UGI A;  4UXH A;  2FNF X;  2GVI A;  2B8T A;  5FUY A;  4UXI A;  2J9R A;  3UEY A;  1W4R A;  2QQ0 A;  3UGL A;  3UFF A;  2ORV A;  1XBT A;  2QQE A;  4FKD A;  1TBO A;  1R79 A; 
#chains in the Genus database with same CATH topology
 1FAQ A;  5CCL A;  2RC4 A;  3TO6 A;  2KMO A;  2QPO A;  2ENZ A;  4L9M A;  1CGI I;  1DS2 I;  2KMQ A;  5JHW C;  1HDL A;  1Z2I A;  3OVO A;  2DB6 A;  4JCV E;  2P6A C;  3UOE A;  2JXD A;  1S20 A;  1HJA I;  2QQC A;  3E2I A;  5CCM A;  3CXL A;  3GOX A;  1Y1B A;  2WCY A;  2DIP A;  1OVO A;  1XA6 A;  2ORW A;  2OZU A;  3HH2 C;  5E3P A;  1UVG A;  1DS3 I;  1X74 A;  2UZ3 A;  1UVF A;  1V1H A;  1FY7 A;  2L8E A;  1SGQ I;  2W0T A;  1TBQ R;  2N52 A;  3UGI A;  2FNF X;  5E3R A;  1UHA A;  2B8T A;  3RU0 A;  2PQ8 A;  2B0U C;  1SGD I;  1W4R A;  2QQ0 A;  1HPT A;  1SGE I;  2ODD A;  3UEY A;  1OMU A;  3VDP A;  3MEK A;  2QQE A;  1ULN A;  1CT0 I;  2NU3 I;  1R79 A;  2JW6 A;  1Y8F A;  1XX6 A;  2XRC A;  1WGT A;  2VRW B;  4UXJ A;  2A20 A;  1KBE A;  1CHO I;  2SGF I;  1W3S A;  1ULK A;  4DNC A;  1BMO A;  1TOT A;  1TGS I;  2GIV A;  1YTP A;  4MPI A;  3TO7 A;  1TBN A;  2OD1 A;  3OL0 A;  5FUX A;  2RIJ A;  3SEK C;  2CJS C;  2UVO A;  1R0R I;  2SGD I;  1MJB A;  2YQP A;  1FAR A;  1OMT A;  1PCE A;  1SGN I;  2OVO A;  1MT1 A;  2SGP I;  2KMR A;  2V53 A;  2NU4 I;  1BUS A;  1CGJ I;  4WP4 A;  3R5A A;  1Y1C A;  3FC3 A;  3VE5 A;  1CT2 I;  1NXU A;  1MJA A;  1H0Z A;  1P9Z A;  2NU2 I;  5EX3 A;  2X3T A;  3QAH A;  3UFF A;  5J8F A;  4FKD A;  3E59 A;  3TJQ A;  2M5X A;  5J8C A;  2E73 A;  1WKX A;  2LB7 A;  2GKV A;  3QWP A;  2YUU A;  3SGB I;  1HEV A;  2GKT I;  2WVJ A;  3BJI A;  3TO9 A;  2Y0M A;  1N13 A;  2V1C C;  1IW4 A;  5E3Q A;  3UEJ A;  1PTR A;  1CT4 I;  3QTL D;  2KMP A;  4E1R A;  2SGE I;  1TUR A;  2N71 A;  1OYV I;  2KCX A;  3UGD A;  1CSO I;  1WGC A;  1K7V A;  1LR7 A;  2JA1 A;  1LR8 A;  2ROW A;  2V1C A;  4OVO A;  7WGA A;  1FYB A;  5FUV A;  1TIH A;  2X52 A;  1RFH A;  3KY9 A;  5FUW A;  2SGQ I;  1Z7K B;  1M8C A;  1ULM A;  2GVI A;  3FSY A;  1AN1 I;  1K7U A;  4UXH A;  1KMA A;  5FUY A;  2K9H A;  2JZM A;  3R5C A;  4SGB I;  2J9R A;  5EX0 A;  3SGQ I;  3TOA A;  3UGL A;  5HQ8 A;  2N1A B;  1TBR R;  1UUC A;  4GI3 C;  1SGP I;  1TBO A;  2L7X A;  2GKR I;  3FSX A;  4A24 A;  1V1I A;  1NUB A;  1PPF I;  1M8B A;  1SGR I;  2ARP F;  2QQD A;  2J87 A;  2LUY A;  1LR9 A;  2N17 A;  3VDU A;  1MJ9 A;  1KBF A;  1Q9B A;  3R5D A;  1X4S A;  2E5R A;  1P9G A;  2DKV A;  9WGA A;  1IY5 A;  2BUS A;  3OXF A;  2ENN A;  2LEO A;  2OU2 A;  1K7T A;  2NU0 I;  4E1P A;  1WTJ A;  1VDD A;  2WGC A;  1PTQ A;  4HGU A;  3B4V C;  2ELI A;  1IY6 A;  3PDN A;  1CE3 A;  3D00 A;  2CWG A;  2CWF A;  4AML A;  3TOB A;  4UXI A;  1YU6 C;  5DAE A;  1SGY I;  5HI7 A;  3OXG A;  1PJU A;  1TUS A;  2F3C I;  2JYY A;  1XBT A;  2CWH A;  2ORV A;  3OXL A;  3R5B A;  1U5K A;  2NU1 I;  2ERW A;  4B6D A; 
#chains in the Genus database with same CATH homology
 1FAQ A;  5CCL A;  2KMO A;  2QPO A;  2ENZ A;  4L9M A;  1CGI I;  1DS2 I;  2KMQ A;  5JHW C;  1HDL A;  3OVO A;  2DB6 A;  4JCV E;  2P6A C;  2JXD A;  2QQC A;  1HJA I;  3E2I A;  5CCM A;  3CXL A;  3GOX A;  1Y1B A;  2WCY A;  2DIP A;  1OVO A;  1XA6 A;  2ORW A;  3HH2 C;  1UVG A;  1DS3 I;  1X74 A;  2UZ3 A;  1UVF A;  1V1H A;  2L8E A;  1SGQ I;  2W0T A;  1TBQ R;  2N52 A;  3UGI A;  2FNF X;  2B8T A;  3RU0 A;  2B0U C;  1SGD I;  1W4R A;  2QQ0 A;  1HPT A;  1SGE I;  2ODD A;  3UEY A;  1OMU A;  3VDP A;  3MEK A;  2QQE A;  1CT0 I;  2NU3 I;  1R79 A;  2JW6 A;  1Y8F A;  1XX6 A;  2XRC A;  2VRW B;  4UXJ A;  2A20 A;  1KBE A;  1CHO I;  2SGF I;  1W3S A;  1BMO A;  1TOT A;  1TGS I;  1YTP A;  1TBN A;  2OD1 A;  3OL0 A;  5FUX A;  3SEK C;  2CJS C;  1R0R I;  2SGD I;  2YQP A;  1FAR A;  1OMT A;  1PCE A;  1SGN I;  2OVO A;  1MT1 A;  2SGP I;  2KMR A;  2V53 A;  2NU4 I;  1BUS A;  1CGJ I;  3FC3 A;  1Y1C A;  3VE5 A;  1CT2 I;  1H0Z A;  2NU2 I;  5EX3 A;  3UFF A;  4FKD A;  3E59 A;  3TJQ A;  2M5X A;  2E73 A;  2GKV A;  3QWP A;  2YUU A;  3SGB I;  2GKT I;  2WVJ A;  3BJI A;  1N13 A;  2V1C C;  1IW4 A;  3UEJ A;  1PTR A;  1CT4 I;  3QTL D;  2KMP A;  4E1R A;  2SGE I;  1TUR A;  2N71 A;  1OYV I;  2KCX A;  3UGD A;  1CSO I;  1LR7 A;  2JA1 A;  1LR8 A;  2ROW A;  2V1C A;  4OVO A;  1FYB A;  5FUV A;  1TIH A;  1RFH A;  3KY9 A;  5FUW A;  2SGQ I;  1Z7K B;  1M8C A;  4UXH A;  2GVI A;  1AN1 I;  1KMA A;  5FUY A;  2K9H A;  2JZM A;  4SGB I;  5EX0 A;  2J9R A;  3SGQ I;  5HQ8 A;  3UGL A;  2N1A B;  1TBR R;  1UUC A;  4GI3 C;  1SGP I;  1TBO A;  2L7X A;  2GKR I;  4A24 A;  1V1I A;  1NUB A;  1PPF I;  1M8B A;  1SGR I;  2ARP F;  2QQD A;  2J87 A;  2LUY A;  1LR9 A;  2N17 A;  3VDU A;  1KBF A;  1X4S A;  2E5R A;  1IY5 A;  2BUS A;  3OXF A;  2ENN A;  2LEO A;  4E1P A;  2NU0 I;  1VDD A;  1PTQ A;  4HGU A;  3B4V C;  2ELI A;  1IY6 A;  3PDN A;  1CE3 A;  3D00 A;  4UXI A;  1YU6 C;  5DAE A;  1SGY I;  5HI7 A;  3OXG A;  1PJU A;  1TUS A;  2F3C I;  2JYY A;  1XBT A;  2ORV A;  3OXL A;  1U5K A;  2NU1 I;  2ERW A;  4B6D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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