1YTPA

Solution structure of the c4a/c41a variant of the nicotiana alata proteinase inhibitor t1
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
53
structure length
53
Chain Sequence
DRIATNCCAGTKGCKYFSDDGTFVCEGESDPRNPKACPRNADPRIAYGICPLA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of a disulfide mutant of the Nicotiana alata proteinase inhibitor T1 --- Stabilisation of the reactive site loop is critical for activity
rcsb
molecule tags Hydrolase inhibitor
source organism Nicotiana alata
molecule keywords proteinase inhibitor
total genus 10
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2005-02-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1ytpA00
1CHOI 2WCYA 1UUCA 2BUSA 2SGEI 2ARPF 1PPFI 1Y1CA 2JYYA 1HPTA 2V53A 3OVOA 4OVOA 1CSOI 1OYVI 1OMUA 5JHWC 1PJUA 1TUSA 2KCXA 2QQCA 1OVOA 1SGPI 1LR9A 2JXDA 1IY5A 3B4VC 1MT1A 1AN1I 1BMOA 4SGBI 1CT2I 3SGBI 2LEOA 2NU1I 3SEKC 1HDLA 1CT4I 3TJQA 1HJAI 1UVGA 1CGJI 2N52A 2SGFI 4GI3C 1N13A 1M8CA 2N71A 2F3CI 1H0ZA 1OMTA 1FYBA 2SGQI 1DS2I 2SGDI 1UVFA 5DAEA 1IY6A 1TURA 2QQDA 1NUBA 1BUSA 2KMQA 1SGYI 1SGEI 2GKRI 1PCEA 1TGSI 3HH2C 2P6AC 2B0UC 2NU3I 2ERWA 1TIHA 2NU0I 1CGII 1IW4A 2KMRA 1LR8A 1DS3I 2NU2I 1Z7KB 1YTPA 3QTLD 2KMPA 1YU6C 1CE3A 2OVOA 1CT0I 1TBRR 2N17A 1SGNI 4HGUA 2M5XA 1LR7A 1SGQI 2XRCA 1TBQR 1SGDI 1Y1BA 2JZMA 1M8BA 2SGPI 1KMAA 1SGRI 3SGQI 2GKVA 1R0RI 2KMOA 2GKTI 2NU4I
chains in the Genus database with same CATH superfamily
2CWFA 1CHOI 2WCYA 4B6DA 1UUCA 2BUSA 2OD1A 3E59A 1XX6A 4E1RA 3PDNA 2SGEI 2ARPF 1PPFI 1Y1CA 4AMLA 2JYYA 1HPTA 2V53A 1MJBA 2E5RA 1K7TA 2E73A 1XBTA 3OVOA 4OVOA 3UGLA 2J87A 2DB6A 3VDPA 5E3RA 3QWPA 3MEKA 1CSOI 2X3TA 1NXUA 1OYVI 2X52A 1OMUA 5JHWC 3GOXA 2V1CC 3UOEA 1W4RA 1PJUA 1TUSA 2KCXA 2QQCA 1OVOA 3TOAA 1SGPI 1K7VA 1P9ZA 1LR9A 4UXHA 3R5CA 2ODDA 1PTQA 1V1IA 2JXDA 2FNFX 1MJ9A 1IY5A 2A20A 3UEJA 3B4VC 4UXIA 1MT1A 3TO7A 1UHAA 1ULMA 1MJAA 1Z2IA 5EX0A 4E1PA 5CCLA 1AN1I 1BMOA 1ULKA 2CWHA 1KBEA 2QPOA 1CT2I 2ROWA 4SGBI 4MPIA 5FUWA 3SGBI 1Y8FA 2LEOA 2NU1I 3R5DA 3SEKC 2GIVA 1HDLA 1TBOA 5FUXA 1CT4I 3TJQA 2OZUA 1HJAI 1P9GA 1UVGA 1CGJI 2N52A 2SGFI 3OXFA 4GI3C 1HEVA 1N13A 2JA1A 1M8CA 2K9HA 2N71A 3OXGA 5J8CA 3FC3A 1K7UA 2F3CI 3R5BA 1H0ZA 5HI7A 1OMTA 2N1AB 4UXJA 2ENNA 3FSYA 1FYBA 2PQ8A 2SGQI 1DS2I 2SGDI 1FARA 1UVFA 3FSXA 7WGAA 5DAEA 2L8EA 1IY6A 3TO9A 2RC4A 1TURA 5CCMA 4JCVE 2Y0MA 2V1CA 2QQDA 4L9MA 1NUBA 2DIPA 1BUSA 5FUVA 3UEYA 1TOTA 2QQEA 3UGIA 2KMQA 1SGYI 3UFFA 1SGEI 2GKRI 2ORVA 1PCEA 1TGSI 3HH2C 3VDUA 1WGCA 1VDDA 2CJSC 2P6AC 2B0UC 2JW6A 2NU3I 9WGAA 2ERWA 5E3QA 3R5AA 3UGDA 2ORWA 1TIHA 2NU0I 3QAHA 5EX3A 2VRWB 1CGII 5E3PA 1IW4A 1V1HA 1WKXA 1XA6A 2DKVA 3CXLA 2KMRA 5J8FA 3RU0A 1W3SA 2B8TA 2QQ0A 4DNCA 2WGCA 1LR8A 1DS3I 1FY7A 1WGTA 1YTPA 1WTJA 1RFHA 1Z7KB 2CWGA 2GVIA 2L7XA 2NU2I 2KMPA 2OU2A 1YU6C 4FKDA 5FUYA 4A24A 1X4SA 3TO6A 1TBNA 1CE3A 3TOBA 3QTLD 2YUUA 1X74A 2OVOA 1CT0I 3E2IA 1TBRR 2N17A 1SGNI 2W0TA 1R79A 3KY9A 2M5XA 4HGUA 1FAQA 5HQ8A 2UZ3A 1LR7A 1U5KA 1SGQI 2XRCA 2ENZA 1TBQR 2WVJA 1SGDI 1S20A 2UVOA 1Y1BA 3D00A 2JZMA 1M8BA 2SGPI 3OXLA 1KMAA 1SGRI 3SGQI 2GKVA 2J9RA 1PTRA 1R0RI 1KBFA 2YQPA 3OL0A 4WP4A 3VE5A 2LB7A 2KMOA 2LUYA 1ULNA 2GKTI 2NU4I 2RIJA 3BJIA 1Q9BA 2ELIA
chains in the Genus database with same CATH topology
1CHOI 2WCYA 4B6DA 1UUCA 2BUSA 2OD1A 3E59A 1XX6A 4E1RA 3PDNA 2SGEI 2ARPF 1PPFI 1Y1CA 2JYYA 1HPTA 2V53A 2E5RA 2E73A 3OVOA 1XBTA 3UGLA 4OVOA 2J87A 2DB6A 3VDPA 3QWPA 3MEKA 1CSOI 1OYVI 1OMUA 5JHWC 3GOXA 2V1CC 1W4RA 1PJUA 1TUSA 2KCXA 2QQCA 1OVOA 1SGPI 4UXHA 1LR9A 2ODDA 1PTQA 1V1IA 2JXDA 2FNFX 1IY5A 2A20A 3UEJA 3B4VC 4UXIA 1MT1A 5EX0A 4E1PA 5CCLA 1AN1I 1BMOA 4SGBI 5FUWA 1KBEA 2QPOA 1CT2I 2ROWA 3UFFA 3SGBI 1Y8FA 2LEOA 2NU1I 3SEKC 1HDLA 1TBOA 5FUXA 1CT4I 3TJQA 1HJAI 1UVGA 1CGJI 2N52A 2SGFI 3OXFA 4GI3C 1N13A 2JA1A 1M8CA 2K9HA 2N71A 3OXGA 3FC3A 2F3CI 1H0ZA 5HI7A 1OMTA 2N1AB 4UXJA 2ENNA 1FYBA 2SGQI 1DS2I 2SGDI 1FARA 1UVFA 5DAEA 2L8EA 1IY6A 1TURA 5CCMA 4JCVE 2V1CA 2QQDA 4L9MA 1NUBA 2DIPA 1BUSA 5FUVA 3UEYA 1TOTA 2QQEA 3UGIA 2KMQA 1SGYI 1SGEI 2GKRI 2ORVA 1PCEA 1TGSI 3HH2C 3VDUA 2CJSC 1VDDA 2P6AC 2B0UC 2JW6A 2NU3I 2ERWA 3UGDA 2ORWA 1TIHA 2NU0I 5EX3A 2VRWB 1CGII 1IW4A 1V1HA 1XA6A 3CXLA 2KMRA 3RU0A 1W3SA 2B8TA 2QQ0A 1LR8A 1DS3I 1Z7KB 1YTPA 2NU2I 1RFHA 2GVIA 3QTLD 5FUYA 2L7XA 2KMPA 4FKDA 1YU6C 4A24A 1X4SA 1TBNA 1CE3A 2YUUA 1X74A 2OVOA 1CT0I 3E2IA 1TBRR 2N17A 1SGNI 2W0TA 1R79A 3KY9A 2M5XA 4HGUA 1FAQA 5HQ8A 2UZ3A 1LR7A 1U5KA 1SGQI 2XRCA 2ENZA 1TBQR 2WVJA 1SGDI 1Y1BA 3D00A 2JZMA 1M8BA 2SGPI 3OXLA 1KMAA 1SGRI 3SGQI 2GKVA 2J9RA 1PTRA 1R0RI 1KBFA 2YQPA 3OL0A 3VE5A 2LUYA 2KMOA 2GKTI 2NU4I 3BJIA 2ELIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CHO I;  2WCY A;  1UUC A;  2BUS A;  2SGE I;  2ARP F;  1PPF I;  1Y1C A;  2JYY A;  1HPT A;  2V53 A;  3OVO A;  4OVO A;  1CSO I;  1OYV I;  1OMU A;  5JHW C;  1PJU A;  1TUS A;  2KCX A;  2QQC A;  1OVO A;  1SGP I;  1LR9 A;  2JXD A;  1IY5 A;  3B4V C;  1MT1 A;  1AN1 I;  1BMO A;  4SGB I;  1CT2 I;  3SGB I;  2LEO A;  2NU1 I;  3SEK C;  1HDL A;  1CT4 I;  3TJQ A;  1HJA I;  1UVG A;  1CGJ I;  2N52 A;  2SGF I;  4GI3 C;  1N13 A;  1M8C A;  2N71 A;  2F3C I;  1H0Z A;  1OMT A;  1FYB A;  2SGQ I;  1DS2 I;  2SGD I;  1UVF A;  5DAE A;  1IY6 A;  1TUR A;  2QQD A;  1NUB A;  1BUS A;  2KMQ A;  1SGY I;  1SGE I;  2GKR I;  1PCE A;  1TGS I;  3HH2 C;  2P6A C;  2B0U C;  2NU3 I;  2ERW A;  1TIH A;  2NU0 I;  1CGI I;  1IW4 A;  2KMR A;  1LR8 A;  1DS3 I;  2NU2 I;  1Z7K B;  1YTP A;  3QTL D;  2KMP A;  1YU6 C;  1CE3 A;  2OVO A;  1CT0 I;  1TBR R;  2N17 A;  1SGN I;  4HGU A;  2M5X A;  1LR7 A;  1SGQ I;  2XRC A;  1TBQ R;  1SGD I;  1Y1B A;  2JZM A;  1M8B A;  2SGP I;  1KMA A;  1SGR I;  3SGQ I;  2GKV A;  1R0R I;  2KMO A;  2GKT I;  2NU4 I; 
#chains in the Genus database with same CATH topology
 2CWF A;  1CHO I;  2WCY A;  4B6D A;  1UUC A;  2BUS A;  2OD1 A;  3E59 A;  1XX6 A;  4E1R A;  3PDN A;  2SGE I;  2ARP F;  1PPF I;  1Y1C A;  4AML A;  2JYY A;  1HPT A;  2V53 A;  1MJB A;  2E5R A;  1K7T A;  2E73 A;  1XBT A;  3OVO A;  4OVO A;  3UGL A;  2J87 A;  2DB6 A;  3VDP A;  5E3R A;  3QWP A;  3MEK A;  1CSO I;  2X3T A;  1NXU A;  1OYV I;  2X52 A;  1OMU A;  5JHW C;  3GOX A;  2V1C C;  3UOE A;  1W4R A;  1PJU A;  1TUS A;  2KCX A;  2QQC A;  1OVO A;  3TOA A;  1SGP I;  1K7V A;  1P9Z A;  1LR9 A;  4UXH A;  3R5C A;  2ODD A;  1PTQ A;  1V1I A;  2JXD A;  2FNF X;  1MJ9 A;  1IY5 A;  2A20 A;  3UEJ A;  3B4V C;  4UXI A;  1MT1 A;  3TO7 A;  1UHA A;  1ULM A;  1MJA A;  1Z2I A;  5EX0 A;  4E1P A;  5CCL A;  1AN1 I;  1BMO A;  1ULK A;  2CWH A;  1KBE A;  2QPO A;  1CT2 I;  2ROW A;  4SGB I;  4MPI A;  5FUW A;  3SGB I;  1Y8F A;  2LEO A;  2NU1 I;  3R5D A;  3SEK C;  2GIV A;  1HDL A;  1TBO A;  5FUX A;  1CT4 I;  3TJQ A;  2OZU A;  1HJA I;  1P9G A;  1UVG A;  1CGJ I;  2N52 A;  2SGF I;  3OXF A;  4GI3 C;  1HEV A;  1N13 A;  2JA1 A;  1M8C A;  2K9H A;  2N71 A;  3OXG A;  5J8C A;  3FC3 A;  1K7U A;  2F3C I;  3R5B A;  1H0Z A;  5HI7 A;  1OMT A;  2N1A B;  4UXJ A;  2ENN A;  3FSY A;  1FYB A;  2PQ8 A;  2SGQ I;  1DS2 I;  2SGD I;  1FAR A;  1UVF A;  3FSX A;  7WGA A;  5DAE A;  2L8E A;  1IY6 A;  3TO9 A;  2RC4 A;  1TUR A;  5CCM A;  4JCV E;  2Y0M A;  2V1C A;  2QQD A;  4L9M A;  1NUB A;  2DIP A;  1BUS A;  5FUV A;  3UEY A;  1TOT A;  2QQE A;  3UGI A;  2KMQ A;  1SGY I;  3UFF A;  1SGE I;  2GKR I;  2ORV A;  1PCE A;  1TGS I;  3HH2 C;  3VDU A;  1WGC A;  1VDD A;  2CJS C;  2P6A C;  2B0U C;  2JW6 A;  2NU3 I;  9WGA A;  2ERW A;  5E3Q A;  3R5A A;  3UGD A;  2ORW A;  1TIH A;  2NU0 I;  3QAH A;  5EX3 A;  2VRW B;  1CGI I;  5E3P A;  1IW4 A;  1V1H A;  1WKX A;  1XA6 A;  2DKV A;  3CXL A;  2KMR A;  5J8F A;  3RU0 A;  1W3S A;  2B8T A;  2QQ0 A;  4DNC A;  2WGC A;  1LR8 A;  1DS3 I;  1FY7 A;  1WGT A;  1YTP A;  1WTJ A;  1RFH A;  1Z7K B;  2CWG A;  2GVI A;  2L7X A;  2NU2 I;  2KMP A;  2OU2 A;  1YU6 C;  4FKD A;  5FUY A;  4A24 A;  1X4S A;  3TO6 A;  1TBN A;  1CE3 A;  3TOB A;  3QTL D;  2YUU A;  1X74 A;  2OVO A;  1CT0 I;  3E2I A;  1TBR R;  2N17 A;  1SGN I;  2W0T A;  1R79 A;  3KY9 A;  2M5X A;  4HGU A;  1FAQ A;  5HQ8 A;  2UZ3 A;  1LR7 A;  1U5K A;  1SGQ I;  2XRC A;  2ENZ A;  1TBQ R;  2WVJ A;  1SGD I;  1S20 A;  2UVO A;  1Y1B A;  3D00 A;  2JZM A;  1M8B A;  2SGP I;  3OXL A;  1KMA A;  1SGR I;  3SGQ I;  2GKV A;  2J9R A;  1PTR A;  1R0R I;  1KBF A;  2YQP A;  3OL0 A;  4WP4 A;  3VE5 A;  2LB7 A;  2KMO A;  2LUY A;  1ULN A;  2GKT I;  2NU4 I;  2RIJ A;  3BJI A;  1Q9B A;  2ELI A; 
#chains in the Genus database with same CATH homology
 1CHO I;  2WCY A;  4B6D A;  1UUC A;  2BUS A;  2OD1 A;  3E59 A;  1XX6 A;  4E1R A;  3PDN A;  2SGE I;  2ARP F;  1PPF I;  1Y1C A;  2JYY A;  1HPT A;  2V53 A;  2E5R A;  2E73 A;  3OVO A;  1XBT A;  3UGL A;  4OVO A;  2J87 A;  2DB6 A;  3VDP A;  3QWP A;  3MEK A;  1CSO I;  1OYV I;  1OMU A;  5JHW C;  3GOX A;  2V1C C;  1W4R A;  1PJU A;  1TUS A;  2KCX A;  2QQC A;  1OVO A;  1SGP I;  4UXH A;  1LR9 A;  2ODD A;  1PTQ A;  1V1I A;  2JXD A;  2FNF X;  1IY5 A;  2A20 A;  3UEJ A;  3B4V C;  4UXI A;  1MT1 A;  5EX0 A;  4E1P A;  5CCL A;  1AN1 I;  1BMO A;  4SGB I;  5FUW A;  1KBE A;  2QPO A;  1CT2 I;  2ROW A;  3UFF A;  3SGB I;  1Y8F A;  2LEO A;  2NU1 I;  3SEK C;  1HDL A;  1TBO A;  5FUX A;  1CT4 I;  3TJQ A;  1HJA I;  1UVG A;  1CGJ I;  2N52 A;  2SGF I;  3OXF A;  4GI3 C;  1N13 A;  2JA1 A;  1M8C A;  2K9H A;  2N71 A;  3OXG A;  3FC3 A;  2F3C I;  1H0Z A;  5HI7 A;  1OMT A;  2N1A B;  4UXJ A;  2ENN A;  1FYB A;  2SGQ I;  1DS2 I;  2SGD I;  1FAR A;  1UVF A;  5DAE A;  2L8E A;  1IY6 A;  1TUR A;  5CCM A;  4JCV E;  2V1C A;  2QQD A;  4L9M A;  1NUB A;  2DIP A;  1BUS A;  5FUV A;  3UEY A;  1TOT A;  2QQE A;  3UGI A;  2KMQ A;  1SGY I;  1SGE I;  2GKR I;  2ORV A;  1PCE A;  1TGS I;  3HH2 C;  3VDU A;  2CJS C;  1VDD A;  2P6A C;  2B0U C;  2JW6 A;  2NU3 I;  2ERW A;  3UGD A;  2ORW A;  1TIH A;  2NU0 I;  5EX3 A;  2VRW B;  1CGI I;  1IW4 A;  1V1H A;  1XA6 A;  3CXL A;  2KMR A;  3RU0 A;  1W3S A;  2B8T A;  2QQ0 A;  1LR8 A;  1DS3 I;  1Z7K B;  1YTP A;  2NU2 I;  1RFH A;  2GVI A;  3QTL D;  5FUY A;  2L7X A;  2KMP A;  4FKD A;  1YU6 C;  4A24 A;  1X4S A;  1TBN A;  1CE3 A;  2YUU A;  1X74 A;  2OVO A;  1CT0 I;  3E2I A;  1TBR R;  2N17 A;  1SGN I;  2W0T A;  1R79 A;  3KY9 A;  2M5X A;  4HGU A;  1FAQ A;  5HQ8 A;  2UZ3 A;  1LR7 A;  1U5K A;  1SGQ I;  2XRC A;  2ENZ A;  1TBQ R;  2WVJ A;  1SGD I;  1Y1B A;  3D00 A;  2JZM A;  1M8B A;  2SGP I;  3OXL A;  1KMA A;  1SGR I;  3SGQ I;  2GKV A;  2J9R A;  1PTR A;  1R0R I;  1KBF A;  2YQP A;  3OL0 A;  3VE5 A;  2LUY A;  2KMO A;  2GKT I;  2NU4 I;  3BJI A;  2ELI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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