2ELIA

Solution structure of the second phorbol esters/diacylglycerol binding domain of human protein kinase c alpha type
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
85
structure length
85
Chain Sequence
GSSGSSGGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the second Phorbol esters/diacylglycerol binding domain of human Protein kinase C alpha type
rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Protein kinase C alpha type
total genus 4
structure length 85
sequence length 85
ec nomenclature ec 2.7.11.13: Protein kinase C.
pdb deposition date 2007-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00130 C1_1 Phorbol esters/diacylglycerol binding domain (C1 domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.20 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2eliA01
1FARA 1W4RA 1XBTA 4UXJA 3UGIA 5FUYA 4L9MA 4FKDA 3UEJA 3BJIA 2J9RA 2ELIA 2VRWB 2ORWA 3KY9A 5FUVA 2ENNA 2E73A 3UGLA 4UXIA 2GVIA 1R79A 4B6DA 1FAQA 1XX6A 4UXHA 2UZ3A 2FNFX 3E2IA 1KBFA 5FUXA 5FUWA 3CXLA 1PTRA 1TBNA 1XA6A 2J87A 2QQ0A 2QQEA 1Y8FA 1KBEA 3UFFA 2YUUA 2JA1A 2ENZA 2B8TA 2ORVA 1TBOA 2WVJA 3UEYA 3UGDA 1RFHA 1PTQA 2ROWA 2DB6A 2QPOA
chains in the Genus database with same CATH superfamily
1W4RA 1TIHA 4WP4A 2NU1I 1BMOA 5EX0A 2LUYA 5FUYA 4FKDA 1OYVI 3BJIA 2ARPF 5HQ8A 3FSYA 2X52A 3KY9A 3R5AA 5EX3A 3TO7A 1N13A 1TUSA 3SGBI 1V1IA 2A20A 2GIVA 2X3TA 4UXIA 9WGAA 1LR8A 1R79A 1X74A 1YTPA 1OMUA 2GVIA 4B6DA 1SGDI 1XX6A 2UZ3A 2FNFX 1MJBA 3TJQA 3SEKC 1MJ9A 2V53A 3PDNA 3CXLA 5CCLA 3GOXA 1M8BA 2NU4I 1TBNA 2QQEA 2SGDI 2SGEI 2WGCA 1HEVA 1KBEA 1NXUA 3TO6A 1SGNI 2LEOA 1VDDA 2B8TA 2ORVA 3OXLA 3UOEA 4A24A 1IY6A 2V1CC 2NU2I 1ULMA 1AN1I 3TOAA 3R5BA 1RFHA 1Z7KB 1PTQA 2QQCA 2ROWA 1SGEI 1CT0I 2CWHA 3OVOA 1ULKA 1U5KA 1WTJA 1XBTA 2CWFA 2SGQI 2XRCA 5E3PA 5E3RA 3TOBA 1H0ZA 2OZUA 2RIJA 1CGII 1P9ZA 1DS3I 2E5RA 5E3QA 3QAHA 2YQPA 2DIPA 5FUVA 2LB7A 3QWPA 2E73A 1S20A 2KMRA 1LR9A 1FAQA 2CJSC 4UXHA 1KBFA 3OXGA 3MEKA 1TURA 1CT2I 1WKXA 2UVOA 5FUWA 1OMTA 1CT4I 1FY7A 1XA6A 2J87A 1YU6C 2N17A 4SGBI 1V1HA 2BUSA 2PQ8A 2YUUA 3R5DA 1Y1BA 5CCMA 2GKTI 2M5XA 1Q9BA 1LR7A 2QQDA 3UEYA 2DB6A 3SGQI 4E1PA 3OXFA 1X4SA 1KMAA 1UHAA 2WCYA 4UXJA 1PPFI 2SGPI 1PCEA 1HPTA 2JZMA 2V1CA 3RU0A 3VDUA 2OU2A 2VRWB 2GKVA 3FC3A 2ORWA 2F3CI 2SGFI 3E59A 4JCVE 5J8CA 1IW4A 2ENNA 1HJAI 3UGLA 1IY5A 1NUBA 4GI3C 1TOTA 1SGRI 3B4VC 2B0UC 1MT1A 2JYYA 2P6AC 2Y0MA 5J8FA 4MPIA 2L7XA 1TBQR 1CE3A 5JHWC 4HGUA 1MJAA 1PTRA 1K7VA 3VE5A 1OVOA 1PJUA 4E1RA 2ERWA 5HI7A 1WGTA 2JW6A 2N52A 3FSXA 2W0TA 5DAEA 2N71A 1TBOA 2OVOA 3UGDA 2KMOA 7WGAA 1FARA 1SGYI 3HH2C 1K7TA 1UUCA 1FYBA 2NU0I 1R0RI 3UGIA 1M8CA 1SGPI 1SGQI 4L9MA 3TO9A 4DNCA 3UEJA 1CGJI 2J9RA 2ELIA 1BUSA 1DS2I 1UVFA 2L8EA 3OL0A 2ODDA 2KMQA 1CHOI 2NU3I 1HDLA 2GKRI 1Y1CA 2RC4A 3E2IA 4AMLA 1TGSI 1Z2IA 1TBRR 5FUXA 1WGCA 2OD1A 1P9GA 2KMPA 2N1AB 2QQ0A 3D00A 1ULNA 1Y8FA 2DKVA 2JXDA 3UFFA 1CSOI 2JA1A 1W3SA 2CWGA 2ENZA 3QTLD 3R5CA 2WVJA 3VDPA 4OVOA 1UVGA 2KCXA 2QPOA 1K7UA 2K9HA
chains in the Genus database with same CATH topology
1W4RA 1TIHA 2NU1I 1BMOA 5EX0A 2LUYA 5FUYA 4FKDA 1OYVI 3BJIA 2ARPF 5HQ8A 3KY9A 5EX3A 1N13A 1TUSA 3SGBI 1V1IA 2A20A 4UXIA 1LR8A 1R79A 1X74A 1YTPA 1OMUA 2GVIA 4B6DA 1SGDI 1XX6A 2UZ3A 2FNFX 3TJQA 3SEKC 2V53A 3PDNA 3CXLA 5CCLA 3GOXA 1M8BA 2NU4I 1TBNA 2QQEA 2SGDI 2SGEI 1KBEA 1SGNI 2LEOA 1VDDA 2B8TA 2ORVA 3OXLA 4A24A 1IY6A 2V1CC 2NU2I 1AN1I 1RFHA 1Z7KB 1PTQA 2QQCA 2ROWA 1SGEI 1CT0I 3OVOA 1U5KA 2SGQI 1XBTA 2XRCA 1H0ZA 1CGII 1DS3I 2E5RA 2YQPA 2DIPA 5FUVA 3QWPA 2E73A 2KMRA 1LR9A 1FAQA 2CJSC 4UXHA 1KBFA 3OXGA 3MEKA 1TURA 1CT2I 5FUWA 1OMTA 1CT4I 1XA6A 2J87A 1YU6C 2N17A 4SGBI 1V1HA 2BUSA 2YUUA 1Y1BA 5CCMA 2GKTI 2M5XA 2QQDA 1LR7A 3UEYA 2DB6A 3SGQI 4E1PA 3OXFA 1X4SA 2WCYA 4UXJA 1PPFI 2SGPI 1PCEA 1HPTA 2JZMA 2V1CA 3RU0A 3VDUA 2VRWB 2GKVA 3FC3A 2ORWA 2F3CI 2SGFI 3E59A 4JCVE 1IW4A 2ENNA 1HJAI 3UGLA 1IY5A 1NUBA 4GI3C 1TOTA 1SGRI 3B4VC 2B0UC 1MT1A 2JYYA 2P6AC 2L7XA 1TBQR 1CE3A 5JHWC 4HGUA 1PTRA 3VE5A 1OVOA 1PJUA 4E1RA 2ERWA 5HI7A 2JW6A 2N52A 2W0TA 5DAEA 2N71A 1TBOA 2OVOA 3UGDA 2KMOA 1FARA 1SGYI 3HH2C 1UUCA 1FYBA 2NU0I 1R0RI 3UGIA 1M8CA 1SGPI 1SGQI 4L9MA 3UEJA 1CGJI 2J9RA 2ELIA 1BUSA 1DS2I 1UVFA 2L8EA 3OL0A 2ODDA 2KMQA 1CHOI 2NU3I 1HDLA 2GKRI 1Y1CA 3E2IA 1TGSI 1TBRR 5FUXA 2OD1A 2KMPA 2N1AB 2QQ0A 3D00A 1Y8FA 2JXDA 3UFFA 1CSOI 2JA1A 1W3SA 2ENZA 3QTLD 2WVJA 3VDPA 4OVOA 1UVGA 2KCXA 2QPOA 1KMAA 2K9HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FAR A;  1W4R A;  1XBT A;  4UXJ A;  3UGI A;  5FUY A;  4L9M A;  4FKD A;  3UEJ A;  3BJI A;  2J9R A;  2ELI A;  2VRW B;  2ORW A;  3KY9 A;  5FUV A;  2ENN A;  2E73 A;  3UGL A;  4UXI A;  2GVI A;  1R79 A;  4B6D A;  1FAQ A;  1XX6 A;  4UXH A;  2UZ3 A;  2FNF X;  3E2I A;  1KBF A;  5FUX A;  5FUW A;  3CXL A;  1PTR A;  1TBN A;  1XA6 A;  2J87 A;  2QQ0 A;  2QQE A;  1Y8F A;  1KBE A;  3UFF A;  2YUU A;  2JA1 A;  2ENZ A;  2B8T A;  2ORV A;  1TBO A;  2WVJ A;  3UEY A;  3UGD A;  1RFH A;  1PTQ A;  2ROW A;  2DB6 A;  2QPO A; 
#chains in the Genus database with same CATH topology
 1W4R A;  1TIH A;  4WP4 A;  2NU1 I;  1BMO A;  5EX0 A;  2LUY A;  5FUY A;  4FKD A;  1OYV I;  3BJI A;  2ARP F;  5HQ8 A;  3FSY A;  2X52 A;  3KY9 A;  3R5A A;  5EX3 A;  3TO7 A;  1N13 A;  1TUS A;  3SGB I;  1V1I A;  2A20 A;  2GIV A;  2X3T A;  4UXI A;  9WGA A;  1LR8 A;  1R79 A;  1X74 A;  1YTP A;  1OMU A;  2GVI A;  4B6D A;  1SGD I;  1XX6 A;  2UZ3 A;  2FNF X;  1MJB A;  3TJQ A;  3SEK C;  1MJ9 A;  2V53 A;  3PDN A;  3CXL A;  5CCL A;  3GOX A;  1M8B A;  2NU4 I;  1TBN A;  2QQE A;  2SGD I;  2SGE I;  2WGC A;  1HEV A;  1KBE A;  1NXU A;  3TO6 A;  1SGN I;  2LEO A;  1VDD A;  2B8T A;  2ORV A;  3OXL A;  3UOE A;  4A24 A;  1IY6 A;  2V1C C;  2NU2 I;  1ULM A;  1AN1 I;  3TOA A;  3R5B A;  1RFH A;  1Z7K B;  1PTQ A;  2QQC A;  2ROW A;  1SGE I;  1CT0 I;  2CWH A;  3OVO A;  1ULK A;  1U5K A;  1WTJ A;  1XBT A;  2CWF A;  2SGQ I;  2XRC A;  5E3P A;  5E3R A;  3TOB A;  1H0Z A;  2OZU A;  2RIJ A;  1CGI I;  1P9Z A;  1DS3 I;  2E5R A;  5E3Q A;  3QAH A;  2YQP A;  2DIP A;  5FUV A;  2LB7 A;  3QWP A;  2E73 A;  1S20 A;  2KMR A;  1LR9 A;  1FAQ A;  2CJS C;  4UXH A;  1KBF A;  3OXG A;  3MEK A;  1TUR A;  1CT2 I;  1WKX A;  2UVO A;  5FUW A;  1OMT A;  1CT4 I;  1FY7 A;  1XA6 A;  2J87 A;  1YU6 C;  2N17 A;  4SGB I;  1V1H A;  2BUS A;  2PQ8 A;  2YUU A;  3R5D A;  1Y1B A;  5CCM A;  2GKT I;  2M5X A;  1Q9B A;  1LR7 A;  2QQD A;  3UEY A;  2DB6 A;  3SGQ I;  4E1P A;  3OXF A;  1X4S A;  1KMA A;  1UHA A;  2WCY A;  4UXJ A;  1PPF I;  2SGP I;  1PCE A;  1HPT A;  2JZM A;  2V1C A;  3RU0 A;  3VDU A;  2OU2 A;  2VRW B;  2GKV A;  3FC3 A;  2ORW A;  2F3C I;  2SGF I;  3E59 A;  4JCV E;  5J8C A;  1IW4 A;  2ENN A;  1HJA I;  3UGL A;  1IY5 A;  1NUB A;  4GI3 C;  1TOT A;  1SGR I;  3B4V C;  2B0U C;  1MT1 A;  2JYY A;  2P6A C;  2Y0M A;  5J8F A;  4MPI A;  2L7X A;  1TBQ R;  1CE3 A;  5JHW C;  4HGU A;  1MJA A;  1PTR A;  1K7V A;  3VE5 A;  1OVO A;  1PJU A;  4E1R A;  2ERW A;  5HI7 A;  1WGT A;  2JW6 A;  2N52 A;  3FSX A;  2W0T A;  5DAE A;  2N71 A;  1TBO A;  2OVO A;  3UGD A;  2KMO A;  7WGA A;  1FAR A;  1SGY I;  3HH2 C;  1K7T A;  1UUC A;  1FYB A;  2NU0 I;  1R0R I;  3UGI A;  1M8C A;  1SGP I;  1SGQ I;  4L9M A;  3TO9 A;  4DNC A;  3UEJ A;  1CGJ I;  2J9R A;  2ELI A;  1BUS A;  1DS2 I;  1UVF A;  2L8E A;  3OL0 A;  2ODD A;  2KMQ A;  1CHO I;  2NU3 I;  1HDL A;  2GKR I;  1Y1C A;  2RC4 A;  3E2I A;  4AML A;  1TGS I;  1Z2I A;  1TBR R;  5FUX A;  1WGC A;  2OD1 A;  1P9G A;  2KMP A;  2N1A B;  2QQ0 A;  3D00 A;  1ULN A;  1Y8F A;  2DKV A;  2JXD A;  3UFF A;  1CSO I;  2JA1 A;  1W3S A;  2CWG A;  2ENZ A;  3QTL D;  3R5C A;  2WVJ A;  3VDP A;  4OVO A;  1UVG A;  2KCX A;  2QPO A;  1K7U A;  2K9H A; 
#chains in the Genus database with same CATH homology
 1W4R A;  1TIH A;  2NU1 I;  1BMO A;  5EX0 A;  2LUY A;  5FUY A;  4FKD A;  1OYV I;  3BJI A;  2ARP F;  5HQ8 A;  3KY9 A;  5EX3 A;  1N13 A;  1TUS A;  3SGB I;  1V1I A;  2A20 A;  4UXI A;  1LR8 A;  1R79 A;  1X74 A;  1YTP A;  1OMU A;  2GVI A;  4B6D A;  1SGD I;  1XX6 A;  2UZ3 A;  2FNF X;  3TJQ A;  3SEK C;  2V53 A;  3PDN A;  3CXL A;  5CCL A;  3GOX A;  1M8B A;  2NU4 I;  1TBN A;  2QQE A;  2SGD I;  2SGE I;  1KBE A;  1SGN I;  2LEO A;  1VDD A;  2B8T A;  2ORV A;  3OXL A;  4A24 A;  1IY6 A;  2V1C C;  2NU2 I;  1AN1 I;  1RFH A;  1Z7K B;  1PTQ A;  2QQC A;  2ROW A;  1SGE I;  1CT0 I;  3OVO A;  1U5K A;  2SGQ I;  1XBT A;  2XRC A;  1H0Z A;  1CGI I;  1DS3 I;  2E5R A;  2YQP A;  2DIP A;  5FUV A;  3QWP A;  2E73 A;  2KMR A;  1LR9 A;  1FAQ A;  2CJS C;  4UXH A;  1KBF A;  3OXG A;  3MEK A;  1TUR A;  1CT2 I;  5FUW A;  1OMT A;  1CT4 I;  1XA6 A;  2J87 A;  1YU6 C;  2N17 A;  4SGB I;  1V1H A;  2BUS A;  2YUU A;  1Y1B A;  5CCM A;  2GKT I;  2M5X A;  2QQD A;  1LR7 A;  3UEY A;  2DB6 A;  3SGQ I;  4E1P A;  3OXF A;  1X4S A;  2WCY A;  4UXJ A;  1PPF I;  2SGP I;  1PCE A;  1HPT A;  2JZM A;  2V1C A;  3RU0 A;  3VDU A;  2VRW B;  2GKV A;  3FC3 A;  2ORW A;  2F3C I;  2SGF I;  3E59 A;  4JCV E;  1IW4 A;  2ENN A;  1HJA I;  3UGL A;  1IY5 A;  1NUB A;  4GI3 C;  1TOT A;  1SGR I;  3B4V C;  2B0U C;  1MT1 A;  2JYY A;  2P6A C;  2L7X A;  1TBQ R;  1CE3 A;  5JHW C;  4HGU A;  1PTR A;  3VE5 A;  1OVO A;  1PJU A;  4E1R A;  2ERW A;  5HI7 A;  2JW6 A;  2N52 A;  2W0T A;  5DAE A;  2N71 A;  1TBO A;  2OVO A;  3UGD A;  2KMO A;  1FAR A;  1SGY I;  3HH2 C;  1UUC A;  1FYB A;  2NU0 I;  1R0R I;  3UGI A;  1M8C A;  1SGP I;  1SGQ I;  4L9M A;  3UEJ A;  1CGJ I;  2J9R A;  2ELI A;  1BUS A;  1DS2 I;  1UVF A;  2L8E A;  3OL0 A;  2ODD A;  2KMQ A;  1CHO I;  2NU3 I;  1HDL A;  2GKR I;  1Y1C A;  3E2I A;  1TGS I;  1TBR R;  5FUX A;  2OD1 A;  2KMP A;  2N1A B;  2QQ0 A;  3D00 A;  1Y8F A;  2JXD A;  3UFF A;  1CSO I;  2JA1 A;  1W3S A;  2ENZ A;  3QTL D;  2WVJ A;  3VDP A;  4OVO A;  1UVG A;  2KCX A;  2QPO A;  1KMA A;  2K9H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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