2JXDA

Nmr structure of human serine protease inhibitor kazal type ii (spink2)
Total Genus 9
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
62
structure length
62
Chain Sequence
PQFGLFSKYRTPNCSQYRLPGCPRHFNPVCGSDMSTYANECTLCMKIREGGHNIKIIRNGPC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Identification of trypsin-inhibitory site and structure determination of human SPINK2 serine proteinase inhibitor
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Homo sapiens
molecule keywords Serine protease inhibitor Kazal-type 2
total genus 9
structure length 62
sequence length 62
ec nomenclature
pdb deposition date 2007-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2jxdA00
1CT4I 1IY6A 1CT0I 2JXDA 1N13A 2LEOA 1HDLA 2SGEI 2NU1I 1KMAA 1FYBA 1SGNI 4GI3C 2M5XA 1SGRI 1BUSA 1BMOA 1MT1A 1M8CA 1OMTA 1IY5A 2N17A 1UVGA 1TBRR 2KMPA 1M8BA 1R0RI 1SGEI 3B4VC 2NU4I 1SGYI 2GKRI 1IW4A 1CGJI 1TIHA 2ARPF 2N71A 1PJUA 4SGBI 2ERWA 2JZMA 1CE3A 1DS3I 1TBQR 1Y1BA 3TJQA 4HGUA 2KMOA 2V53A 2QQCA 1Z7KB 2GKVA 2SGFI 2F3CI 1H0ZA 1HPTA 2P6AC 2B0UC 1CT2I 1PPFI 2SGQI 1SGQI 2QQDA 2NU2I 2SGDI 3HH2C 3OVOA 2SGPI 1LR8A 1UUCA 1HJAI 2OVOA 1AN1I 1LR7A 1TUSA 1TURA 1CSOI 2BUSA 1UVFA 1OYVI 1OMUA 1SGPI 2XRCA 1CGII 1NUBA 1PCEA 1TGSI 2KMQA 4OVOA 2N52A 1YTPA 3SEKC 1Y1CA 1CHOI 5JHWC 1DS2I 2NU3I 1LR9A 3SGBI 1YU6C 2JYYA 2KMRA 2NU0I 2GKTI 1SGDI 3QTLD 1OVOA 3SGQI 5DAEA 2KCXA 2WCYA
chains in the Genus database with same CATH superfamily
1FARA 2QPOA 2CJSC 5FUYA 1X74A 2ENZA 3TOBA 3VE5A 4B6DA 1CT4I 1IY6A 1CT0I 2JXDA 3TO9A 3OXLA 1N13A 2LEOA 2V1CC 1HDLA 2SGEI 4E1RA 2NU1I 1VDDA 2DKVA 1X4SA 1KMAA 4UXJA 1FYBA 1SGNI 4GI3C 2M5XA 1HEVA 1SGRI 3CXLA 1BUSA 2ROWA 2UZ3A 1BMOA 1MT1A 2RIJA 2OZUA 3KY9A 1M8CA 5HI7A 4UXIA 1OMTA 3D00A 3TO6A 1IY5A 2N17A 1UVGA 1V1HA 2J87A 1TBRR 2KMPA 1M8BA 1R0RI 4A24A 2OD1A 1ULKA 1SGEI 3B4VC 5FUVA 5HQ8A 3GOXA 2NU4I 1PTQA 1SGYI 1Y8FA 2GKRI 1CGJI 1TIHA 3FSXA 1IW4A 3FSYA 1ULMA 7WGAA 4WP4A 2ARPF 2DB6A 2N71A 1PJUA 2VRWB 1MJAA 2E5RA 2QQ0A 4SGBI 5E3RA 5EX0A 3TOAA 3UOEA 1FY7A 2A20A 1MJBA 2RC4A 2B8TA 3R5BA 2ERWA 2CWFA 1P9ZA 5CCMA 2JZMA 1CE3A 1DS3I 3MEKA 1TBQR 1V1IA 1Y1BA 3RU0A 3TJQA 3UEYA 2UVOA 4HGUA 2WGCA 2LUYA 3OL0A 1Q9BA 2ORVA 1WKXA 2KMOA 2ORWA 2E73A 2QQCA 2V53A 2YQPA 5FUWA 3R5DA 2N1AB 1Z7KB 3OXGA 3FC3A 2ELIA 2GKVA 2SGFI 4L9MA 4DNCA 2F3CI 1TBOA 1HPTA 1H0ZA 2V1CA 2YUUA 4AMLA 2P6AC 1U5KA 2B0UC 1CT2I 1XX6A 1PPFI 5EX3A 2SGQI 1SGQI 9WGAA 2QQEA 2QQDA 2NU2I 2GVIA 2SGDI 3HH2C 3OVOA 2SGPI 5E3QA 1LR8A 4UXHA 1UUCA 1HJAI 1FAQA 1W3SA 3PDNA 2PQ8A 1MJ9A 1WGTA 2OVOA 1AN1I 1LR7A 3R5AA 1TUSA 1TURA 2DIPA 3BJIA 5FUXA 1K7UA 2J9RA 2W0TA 5J8CA 1CSOI 2CWGA 1PTRA 1XA6A 2BUSA 4MPIA 3UGLA 1UVFA 3UGIA 5J8FA 3VDUA 1WGCA 1OYVI 1OMUA 1P9GA 1WTJA 1SGPI 2GIVA 4JCVE 2CWHA 2XRCA 3VDPA 2JA1A 1CGII 1NUBA 1PCEA 1XBTA 1TGSI 2KMQA 5CCLA 4OVOA 4FKDA 2N52A 1YTPA 3SEKC 1S20A 1KBFA 3E59A 2K9HA 1Y1CA 3UEJA 1NXUA 3TO7A 1W4RA 1CHOI 5E3PA 1RFHA 4E1PA 5JHWC 2X3TA 1DS2I 2ENNA 3OXFA 2LB7A 2ODDA 2NU3I 1LR9A 3SGBI 1YU6C 3E2IA 3QAHA 2L8EA 2WVJA 1K7TA 2JYYA 2KMRA 2FNFX 2GKTI 2NU0I 2Y0MA 3UGDA 3R5CA 1TBNA 1K7VA 1SGDI 3QTLD 3QWPA 1Z2IA 3UFFA 1KBEA 2L7XA 1UHAA 1TOTA 2X52A 2JW6A 2OU2A 1OVOA 3SGQI 1R79A 5DAEA 2KCXA 1ULNA 2WCYA
chains in the Genus database with same CATH topology
1FARA 2QPOA 2CJSC 5FUYA 1X74A 2ENZA 3VE5A 4B6DA 1CT4I 1IY6A 1CT0I 2JXDA 3OXLA 1N13A 2LEOA 2V1CC 1HDLA 2SGEI 4E1RA 2NU1I 1VDDA 1X4SA 1KMAA 4UXJA 1FYBA 1SGNI 4GI3C 2M5XA 1SGRI 3CXLA 1BUSA 2ROWA 2UZ3A 1BMOA 1MT1A 5HI7A 3KY9A 1M8CA 4UXIA 1OMTA 3D00A 1IY5A 2N17A 1UVGA 1V1HA 2J87A 1TBRR 2KMPA 1M8BA 1R0RI 4A24A 2OD1A 3GOXA 1SGEI 3B4VC 5FUVA 5HQ8A 2NU4I 1PTQA 1SGYI 1Y8FA 2GKRI 1CGJI 1TIHA 1IW4A 2ARPF 2DB6A 2N71A 1PJUA 2VRWB 2E5RA 2QQ0A 4SGBI 5EX0A 2A20A 2B8TA 2ERWA 5CCMA 2JZMA 1CE3A 1DS3I 3MEKA 1TBQR 1V1IA 1Y1BA 3RU0A 3TJQA 3UEYA 4HGUA 2LUYA 3OL0A 2ORVA 2KMOA 2ORWA 2E73A 2QQCA 2V53A 2YQPA 5FUWA 3FC3A 2N1AB 1Z7KB 3OXGA 2ELIA 2GKVA 2SGFI 4L9MA 2F3CI 1TBOA 1HPTA 1H0ZA 2V1CA 2YUUA 2P6AC 2B0UC 1U5KA 1CT2I 1XX6A 1PPFI 5EX3A 2SGQI 1SGQI 2QQEA 2QQDA 2NU2I 2GVIA 2SGDI 3HH2C 3OVOA 2SGPI 1LR8A 4UXHA 1UUCA 1HJAI 1FAQA 1W3SA 3PDNA 2OVOA 1AN1I 1LR7A 1TUSA 1TURA 2DIPA 3BJIA 5FUXA 2J9RA 2W0TA 1CSOI 1PTRA 1XA6A 2BUSA 3UGLA 1UVFA 3UGIA 3VDUA 1OYVI 1OMUA 3VDPA 1SGPI 4JCVE 2XRCA 2JA1A 1CGII 1NUBA 1PCEA 1XBTA 1TGSI 2KMQA 5CCLA 4OVOA 4FKDA 2N52A 1YTPA 3SEKC 1KBFA 3E59A 2K9HA 1Y1CA 3UEJA 1W4RA 1CHOI 4E1PA 1RFHA 5JHWC 1DS2I 2ENNA 3OXFA 2ODDA 2NU3I 1LR9A 3SGBI 1YU6C 3E2IA 2L8EA 2WVJA 2JYYA 2KMRA 2FNFX 2GKTI 2NU0I 3UGDA 1TBNA 1SGDI 3QTLD 3QWPA 3UFFA 1KBEA 2L7XA 1TOTA 2JW6A 1OVOA 3SGQI 1R79A 5DAEA 2KCXA 2WCYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CT4 I;  1IY6 A;  1CT0 I;  2JXD A;  1N13 A;  2LEO A;  1HDL A;  2SGE I;  2NU1 I;  1KMA A;  1FYB A;  1SGN I;  4GI3 C;  2M5X A;  1SGR I;  1BUS A;  1BMO A;  1MT1 A;  1M8C A;  1OMT A;  1IY5 A;  2N17 A;  1UVG A;  1TBR R;  2KMP A;  1M8B A;  1R0R I;  1SGE I;  3B4V C;  2NU4 I;  1SGY I;  2GKR I;  1IW4 A;  1CGJ I;  1TIH A;  2ARP F;  2N71 A;  1PJU A;  4SGB I;  2ERW A;  2JZM A;  1CE3 A;  1DS3 I;  1TBQ R;  1Y1B A;  3TJQ A;  4HGU A;  2KMO A;  2V53 A;  2QQC A;  1Z7K B;  2GKV A;  2SGF I;  2F3C I;  1H0Z A;  1HPT A;  2P6A C;  2B0U C;  1CT2 I;  1PPF I;  2SGQ I;  1SGQ I;  2QQD A;  2NU2 I;  2SGD I;  3HH2 C;  3OVO A;  2SGP I;  1LR8 A;  1UUC A;  1HJA I;  2OVO A;  1AN1 I;  1LR7 A;  1TUS A;  1TUR A;  1CSO I;  2BUS A;  1UVF A;  1OYV I;  1OMU A;  1SGP I;  2XRC A;  1CGI I;  1NUB A;  1PCE A;  1TGS I;  2KMQ A;  4OVO A;  2N52 A;  1YTP A;  3SEK C;  1Y1C A;  1CHO I;  5JHW C;  1DS2 I;  2NU3 I;  1LR9 A;  3SGB I;  1YU6 C;  2JYY A;  2KMR A;  2NU0 I;  2GKT I;  1SGD I;  3QTL D;  1OVO A;  3SGQ I;  5DAE A;  2KCX A;  2WCY A; 
#chains in the Genus database with same CATH topology
 1FAR A;  2QPO A;  2CJS C;  5FUY A;  1X74 A;  2ENZ A;  3TOB A;  3VE5 A;  4B6D A;  1CT4 I;  1IY6 A;  1CT0 I;  2JXD A;  3TO9 A;  3OXL A;  1N13 A;  2LEO A;  2V1C C;  1HDL A;  2SGE I;  4E1R A;  2NU1 I;  1VDD A;  2DKV A;  1X4S A;  1KMA A;  4UXJ A;  1FYB A;  1SGN I;  4GI3 C;  2M5X A;  1HEV A;  1SGR I;  3CXL A;  1BUS A;  2ROW A;  2UZ3 A;  1BMO A;  1MT1 A;  2RIJ A;  2OZU A;  3KY9 A;  1M8C A;  5HI7 A;  4UXI A;  1OMT A;  3D00 A;  3TO6 A;  1IY5 A;  2N17 A;  1UVG A;  1V1H A;  2J87 A;  1TBR R;  2KMP A;  1M8B A;  1R0R I;  4A24 A;  2OD1 A;  1ULK A;  1SGE I;  3B4V C;  5FUV A;  5HQ8 A;  3GOX A;  2NU4 I;  1PTQ A;  1SGY I;  1Y8F A;  2GKR I;  1CGJ I;  1TIH A;  3FSX A;  1IW4 A;  3FSY A;  1ULM A;  7WGA A;  4WP4 A;  2ARP F;  2DB6 A;  2N71 A;  1PJU A;  2VRW B;  1MJA A;  2E5R A;  2QQ0 A;  4SGB I;  5E3R A;  5EX0 A;  3TOA A;  3UOE A;  1FY7 A;  2A20 A;  1MJB A;  2RC4 A;  2B8T A;  3R5B A;  2ERW A;  2CWF A;  1P9Z A;  5CCM A;  2JZM A;  1CE3 A;  1DS3 I;  3MEK A;  1TBQ R;  1V1I A;  1Y1B A;  3RU0 A;  3TJQ A;  3UEY A;  2UVO A;  4HGU A;  2WGC A;  2LUY A;  3OL0 A;  1Q9B A;  2ORV A;  1WKX A;  2KMO A;  2ORW A;  2E73 A;  2QQC A;  2V53 A;  2YQP A;  5FUW A;  3R5D A;  2N1A B;  1Z7K B;  3OXG A;  3FC3 A;  2ELI A;  2GKV A;  2SGF I;  4L9M A;  4DNC A;  2F3C I;  1TBO A;  1HPT A;  1H0Z A;  2V1C A;  2YUU A;  4AML A;  2P6A C;  1U5K A;  2B0U C;  1CT2 I;  1XX6 A;  1PPF I;  5EX3 A;  2SGQ I;  1SGQ I;  9WGA A;  2QQE A;  2QQD A;  2NU2 I;  2GVI A;  2SGD I;  3HH2 C;  3OVO A;  2SGP I;  5E3Q A;  1LR8 A;  4UXH A;  1UUC A;  1HJA I;  1FAQ A;  1W3S A;  3PDN A;  2PQ8 A;  1MJ9 A;  1WGT A;  2OVO A;  1AN1 I;  1LR7 A;  3R5A A;  1TUS A;  1TUR A;  2DIP A;  3BJI A;  5FUX A;  1K7U A;  2J9R A;  2W0T A;  5J8C A;  1CSO I;  2CWG A;  1PTR A;  1XA6 A;  2BUS A;  4MPI A;  3UGL A;  1UVF A;  3UGI A;  5J8F A;  3VDU A;  1WGC A;  1OYV I;  1OMU A;  1P9G A;  1WTJ A;  1SGP I;  2GIV A;  4JCV E;  2CWH A;  2XRC A;  3VDP A;  2JA1 A;  1CGI I;  1NUB A;  1PCE A;  1XBT A;  1TGS I;  2KMQ A;  5CCL A;  4OVO A;  4FKD A;  2N52 A;  1YTP A;  3SEK C;  1S20 A;  1KBF A;  3E59 A;  2K9H A;  1Y1C A;  3UEJ A;  1NXU A;  3TO7 A;  1W4R A;  1CHO I;  5E3P A;  1RFH A;  4E1P A;  5JHW C;  2X3T A;  1DS2 I;  2ENN A;  3OXF A;  2LB7 A;  2ODD A;  2NU3 I;  1LR9 A;  3SGB I;  1YU6 C;  3E2I A;  3QAH A;  2L8E A;  2WVJ A;  1K7T A;  2JYY A;  2KMR A;  2FNF X;  2GKT I;  2NU0 I;  2Y0M A;  3UGD A;  3R5C A;  1TBN A;  1K7V A;  1SGD I;  3QTL D;  3QWP A;  1Z2I A;  3UFF A;  1KBE A;  2L7X A;  1UHA A;  1TOT A;  2X52 A;  2JW6 A;  2OU2 A;  1OVO A;  3SGQ I;  1R79 A;  5DAE A;  2KCX A;  1ULN A;  2WCY A; 
#chains in the Genus database with same CATH homology
 1FAR A;  2QPO A;  2CJS C;  5FUY A;  1X74 A;  2ENZ A;  3VE5 A;  4B6D A;  1CT4 I;  1IY6 A;  1CT0 I;  2JXD A;  3OXL A;  1N13 A;  2LEO A;  2V1C C;  1HDL A;  2SGE I;  4E1R A;  2NU1 I;  1VDD A;  1X4S A;  1KMA A;  4UXJ A;  1FYB A;  1SGN I;  4GI3 C;  2M5X A;  1SGR I;  3CXL A;  1BUS A;  2ROW A;  2UZ3 A;  1BMO A;  1MT1 A;  5HI7 A;  3KY9 A;  1M8C A;  4UXI A;  1OMT A;  3D00 A;  1IY5 A;  2N17 A;  1UVG A;  1V1H A;  2J87 A;  1TBR R;  2KMP A;  1M8B A;  1R0R I;  4A24 A;  2OD1 A;  3GOX A;  1SGE I;  3B4V C;  5FUV A;  5HQ8 A;  2NU4 I;  1PTQ A;  1SGY I;  1Y8F A;  2GKR I;  1CGJ I;  1TIH A;  1IW4 A;  2ARP F;  2DB6 A;  2N71 A;  1PJU A;  2VRW B;  2E5R A;  2QQ0 A;  4SGB I;  5EX0 A;  2A20 A;  2B8T A;  2ERW A;  5CCM A;  2JZM A;  1CE3 A;  1DS3 I;  3MEK A;  1TBQ R;  1V1I A;  1Y1B A;  3RU0 A;  3TJQ A;  3UEY A;  4HGU A;  2LUY A;  3OL0 A;  2ORV A;  2KMO A;  2ORW A;  2E73 A;  2QQC A;  2V53 A;  2YQP A;  5FUW A;  3FC3 A;  2N1A B;  1Z7K B;  3OXG A;  2ELI A;  2GKV A;  2SGF I;  4L9M A;  2F3C I;  1TBO A;  1HPT A;  1H0Z A;  2V1C A;  2YUU A;  2P6A C;  2B0U C;  1U5K A;  1CT2 I;  1XX6 A;  1PPF I;  5EX3 A;  2SGQ I;  1SGQ I;  2QQE A;  2QQD A;  2NU2 I;  2GVI A;  2SGD I;  3HH2 C;  3OVO A;  2SGP I;  1LR8 A;  4UXH A;  1UUC A;  1HJA I;  1FAQ A;  1W3S A;  3PDN A;  2OVO A;  1AN1 I;  1LR7 A;  1TUS A;  1TUR A;  2DIP A;  3BJI A;  5FUX A;  2J9R A;  2W0T A;  1CSO I;  1PTR A;  1XA6 A;  2BUS A;  3UGL A;  1UVF A;  3UGI A;  3VDU A;  1OYV I;  1OMU A;  3VDP A;  1SGP I;  4JCV E;  2XRC A;  2JA1 A;  1CGI I;  1NUB A;  1PCE A;  1XBT A;  1TGS I;  2KMQ A;  5CCL A;  4OVO A;  4FKD A;  2N52 A;  1YTP A;  3SEK C;  1KBF A;  3E59 A;  2K9H A;  1Y1C A;  3UEJ A;  1W4R A;  1CHO I;  4E1P A;  1RFH A;  5JHW C;  1DS2 I;  2ENN A;  3OXF A;  2ODD A;  2NU3 I;  1LR9 A;  3SGB I;  1YU6 C;  3E2I A;  2L8E A;  2WVJ A;  2JYY A;  2KMR A;  2FNF X;  2GKT I;  2NU0 I;  3UGD A;  1TBN A;  1SGD I;  3QTL D;  3QWP A;  3UFF A;  1KBE A;  2L7X A;  1TOT A;  2JW6 A;  1OVO A;  3SGQ I;  1R79 A;  5DAE A;  2KCX A;  2WCY A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...