2KMPA

Solution structure of intermeidate iia of leeck-derived tryptase inhibitor, ldti.
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
44
structure length
44
Chain Sequence
KKVCACPKILKPVCGSDGRTYANSCIARCNGVSIKSEGSCPTGI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Hirudo medicinalis
publication title Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
pubmed doi rcsb
molecule keywords Leech-derived tryptase inhibitor C
total genus 6
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2009-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2kmpA00
1IY6A 5JHWC 2SGFI 5DAEA 4GI3C 2NU3I 1HPTA 2SGEI 1CT4I 1PCEA 1IY5A 1LR8A 1R0RI 2BUSA 1Y1CA 1TGSI 1LR7A 2SGQI 2ERWA 2KMPA 2P6AC 1Z7KB 3SGQI 3TJQA 1YU6C 1TIHA 2QQCA 1SGDI 1DS2I 1TBQR 1CSOI 1CE3A 3HH2C 1UUCA 2NU4I 2SGPI 1YTPA 3OVOA 3B4VC 1IW4A 1SGEI 1SGPI 1AN1I 1OYVI 1TURA 1KMAA 2JXDA 2B0UC 2F3CI 2N17A 1SGYI 2NU0I 1OMUA 2JYYA 2QQDA 2SGDI 4OVOA 2KMQA 2N52A 1SGQI 2KCXA 4SGBI 2GKTI 1TBRR 2ARPF 2KMRA 4HGUA 1DS3I 3SGBI 1BUSA 2XRCA 2WCYA 1PPFI 2NU1I 3SEKC 1N13A 1CHOI 1LR9A 1M8CA 1CT0I 1OMTA 1TUSA 3QTLD 2N71A 1HJAI 2KMOA 2M5XA 1FYBA 1NUBA 1H0ZA 1MT1A 1CGJI 1Y1BA 1HDLA 2GKVA 1OVOA 1CT2I 1SGNI 2LEOA 1SGRI 2V53A 1BMOA 2GKRI 1CGII 1M8BA 1PJUA 1UVGA 1UVFA 2OVOA 2JZMA 2NU2I
chains in the Genus database with same CATH superfamily
2UVOA 7WGAA 4AMLA 4JCVE 2L8EA 4DNCA 3UGIA 1IY6A 4L9MA 1X74A 4MPIA 2JZMA 4B6DA 2QPOA 5CCLA 5JHWC 1WGTA 2OVOA 1FAQA 2QQEA 2SGFI 2UZ3A 1Y8FA 5DAEA 4GI3C 1P9ZA 2NU3I 3FC3A 2ENZA 1HPTA 2SGEI 4UXHA 1CT4I 4A24A 1Q9BA 3FSYA 3OXGA 2CWGA 2WGCA 1PCEA 1XBTA 5J8CA 1IY5A 1LR8A 2RIJA 1MJ9A 1R0RI 2BUSA 2CWHA 1Y1CA 1TGSI 1FY7A 1LR7A 2PQ8A 2SGQI 2YQPA 2ERWA 5E3RA 2LB7A 2KMPA 2FNFX 3OL0A 2L7XA 2P6AC 2CJSC 1Z7KB 5FUXA 3TO6A 1X4SA 2DIPA 3SGQI 3UFFA 5CCMA 1ULNA 1TOTA 3TJQA 2VRWB 3UGDA 1YU6C 1TIHA 5FUVA 2QQCA 2J9RA 1KBEA 4FKDA 1SGDI 1DS2I 1TBQR 1UHAA 1W3SA 1CSOI 2X52A 1CE3A 3HH2C 1UUCA 1TBNA 2NU4I 2LUYA 2SGPI 3RU0A 2E5RA 1MJAA 1PTRA 2W0TA 3TO7A 1YTPA 3OVOA 3B4VC 1IW4A 2GIVA 1SGEI 5HQ8A 2DB6A 2V1CA 2ORVA 1SGPI 1AN1I 4E1RA 1OYVI 1TURA 1WKXA 1U5KA 1PTQA 1KMAA 2JW6A 3BJIA 2DKVA 9WGAA 2JXDA 3MEKA 2JA1A 3TO9A 1PJUA 1K7VA 2B0UC 2F3CI 3R5DA 5FUWA 2N17A 1Z2IA 1MJBA 3E59A 5E3PA 5HI7A 1FARA 2QQ0A 1SGYI 1ULMA 2ELIA 2ENNA 2K9HA 3OXFA 5EX3A 2NU0I 1OMUA 2JYYA 2QQDA 2SGDI 2ORWA 2Y0MA 2KMQA 2N52A 1SGQI 2B8TA 4OVOA 5E3QA 2KCXA 3UEYA 2A20A 1V1HA 4SGBI 2GKTI 1K7TA 1TBRR 1K7UA 2GVIA 3E2IA 1R79A 3VDPA 2ARPF 2KMRA 4HGUA 1DS3I 3PDNA 3SGBI 3UGLA 2OD1A 1BUSA 2XRCA 2WCYA 3R5AA 1PPFI 2NU1I 3QAHA 4UXJA 3D00A 1XX6A 1CHOI 2X3TA 3SEKC 1LR9A 4UXIA 5EX0A 1M8CA 3FSXA 1CT0I 1OMTA 1TUSA 2E73A 3KY9A 4WP4A 3QTLD 2N71A 1WGCA 3VE5A 1HJAI 3CXLA 2KMOA 3R5CA 3VDUA 2M5XA 1V1IA 4E1PA 1HEVA 1FYBA 1NUBA 1H0ZA 5FUYA 3UEJA 1MT1A 2ROWA 3TOAA 2V1CC 1KBFA 1CGJI 1Y1BA 3TOBA 3UOEA 1TBOA 2OZUA 2OU2A 5J8FA 2J87A 1XA6A 1S20A 2GKVA 3OXLA 1HDLA 1OVOA 1VDDA 1CT2I 1SGNI 1W4RA 1NXUA 2CWFA 2LEOA 2ODDA 3QWPA 1SGRI 1P9GA 2V53A 1BMOA 2GKRI 2RC4A 3R5BA 3GOXA 2WVJA 2YUUA 1CGII 1M8BA 1RFHA 1UVGA 1ULKA 1UVFA 1WTJA 2N1AB 1N13A 2NU2I
chains in the Genus database with same CATH topology
4JCVE 2L8EA 1IY6A 3UGIA 4L9MA 1X74A 2JZMA 4B6DA 2QPOA 5CCLA 5JHWC 1FAQA 2OVOA 2QQEA 2SGFI 2UZ3A 1Y8FA 5DAEA 4GI3C 2NU3I 3FC3A 2ENZA 1HPTA 2SGEI 4UXHA 1CT4I 4A24A 3OXGA 1PCEA 1XBTA 1IY5A 1LR8A 1R0RI 2BUSA 1Y1CA 1TGSI 1LR7A 2YQPA 2SGQI 2ERWA 5FUXA 2KMPA 2FNFX 3OL0A 2L7XA 2P6AC 2CJSC 1Z7KB 3UFFA 1X4SA 2DIPA 3SGQI 5CCMA 1TOTA 3TJQA 2VRWB 3UGDA 1YU6C 1TIHA 5FUVA 2QQCA 2J9RA 1KBEA 4FKDA 1SGDI 1DS2I 1TBQR 1W3SA 1CSOI 1CE3A 3HH2C 1UUCA 1TBNA 2NU4I 2LUYA 2SGPI 3RU0A 2E5RA 1PTRA 2W0TA 1YTPA 3OVOA 3B4VC 1IW4A 1SGEI 5HQ8A 2DB6A 2V1CA 2ORVA 1SGPI 1AN1I 4E1RA 1OYVI 1TURA 1U5KA 1PTQA 1KMAA 2JW6A 3BJIA 2JXDA 3MEKA 2JA1A 2B0UC 1PJUA 2F3CI 5FUWA 5HI7A 2N17A 3E59A 1FARA 2QQ0A 1SGYI 3OXFA 2ELIA 2ENNA 2K9HA 5EX3A 2NU0I 1OMUA 2JYYA 2QQDA 2SGDI 2ORWA 4OVOA 2KMQA 2N52A 1SGQI 2B8TA 3UEYA 2KCXA 2A20A 1V1HA 4SGBI 2GKTI 1TBRR 2GVIA 3E2IA 1R79A 3VDPA 2ARPF 2KMRA 4HGUA 1DS3I 3UGLA 3SGBI 1BUSA 2OD1A 2XRCA 2WCYA 1PPFI 2NU1I 3SEKC 4UXJA 3D00A 1XX6A 1CHOI 1LR9A 4UXIA 5EX0A 1M8CA 1CT0I 1OMTA 1TUSA 2E73A 3KY9A 3QTLD 2N71A 3VE5A 1HJAI 3CXLA 2KMOA 3VDUA 2M5XA 1V1IA 4E1PA 1FYBA 1NUBA 1H0ZA 5FUYA 3UEJA 1MT1A 2ROWA 2V1CC 1KBFA 1CGJI 1Y1BA 1TBOA 2J87A 1XA6A 2GKVA 1HDLA 3OXLA 1OVOA 1VDDA 1CT2I 1SGNI 1W4RA 2ODDA 2LEOA 3QWPA 1SGRI 2V53A 1BMOA 2GKRI 3GOXA 2WVJA 2YUUA 1CGII 1M8BA 1RFHA 1UVGA 1UVFA 3PDNA 2N1AB 1N13A 2NU2I
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IY6 A;  5JHW C;  2SGF I;  5DAE A;  4GI3 C;  2NU3 I;  1HPT A;  2SGE I;  1CT4 I;  1PCE A;  1IY5 A;  1LR8 A;  1R0R I;  2BUS A;  1Y1C A;  1TGS I;  1LR7 A;  2SGQ I;  2ERW A;  2KMP A;  2P6A C;  1Z7K B;  3SGQ I;  3TJQ A;  1YU6 C;  1TIH A;  2QQC A;  1SGD I;  1DS2 I;  1TBQ R;  1CSO I;  1CE3 A;  3HH2 C;  1UUC A;  2NU4 I;  2SGP I;  1YTP A;  3OVO A;  3B4V C;  1IW4 A;  1SGE I;  1SGP I;  1AN1 I;  1OYV I;  1TUR A;  1KMA A;  2JXD A;  2B0U C;  2F3C I;  2N17 A;  1SGY I;  2NU0 I;  1OMU A;  2JYY A;  2QQD A;  2SGD I;  4OVO A;  2KMQ A;  2N52 A;  1SGQ I;  2KCX A;  4SGB I;  2GKT I;  1TBR R;  2ARP F;  2KMR A;  4HGU A;  1DS3 I;  3SGB I;  1BUS A;  2XRC A;  2WCY A;  1PPF I;  2NU1 I;  3SEK C;  1N13 A;  1CHO I;  1LR9 A;  1M8C A;  1CT0 I;  1OMT A;  1TUS A;  3QTL D;  2N71 A;  1HJA I;  2KMO A;  2M5X A;  1FYB A;  1NUB A;  1H0Z A;  1MT1 A;  1CGJ I;  1Y1B A;  1HDL A;  2GKV A;  1OVO A;  1CT2 I;  1SGN I;  2LEO A;  1SGR I;  2V53 A;  1BMO A;  2GKR I;  1CGI I;  1M8B A;  1PJU A;  1UVG A;  1UVF A;  2OVO A;  2JZM A;  2NU2 I; 
#chains in the Genus database with same CATH topology
 2UVO A;  7WGA A;  4AML A;  4JCV E;  2L8E A;  4DNC A;  3UGI A;  1IY6 A;  4L9M A;  1X74 A;  4MPI A;  2JZM A;  4B6D A;  2QPO A;  5CCL A;  5JHW C;  1WGT A;  2OVO A;  1FAQ A;  2QQE A;  2SGF I;  2UZ3 A;  1Y8F A;  5DAE A;  4GI3 C;  1P9Z A;  2NU3 I;  3FC3 A;  2ENZ A;  1HPT A;  2SGE I;  4UXH A;  1CT4 I;  4A24 A;  1Q9B A;  3FSY A;  3OXG A;  2CWG A;  2WGC A;  1PCE A;  1XBT A;  5J8C A;  1IY5 A;  1LR8 A;  2RIJ A;  1MJ9 A;  1R0R I;  2BUS A;  2CWH A;  1Y1C A;  1TGS I;  1FY7 A;  1LR7 A;  2PQ8 A;  2SGQ I;  2YQP A;  2ERW A;  5E3R A;  2LB7 A;  2KMP A;  2FNF X;  3OL0 A;  2L7X A;  2P6A C;  2CJS C;  1Z7K B;  5FUX A;  3TO6 A;  1X4S A;  2DIP A;  3SGQ I;  3UFF A;  5CCM A;  1ULN A;  1TOT A;  3TJQ A;  2VRW B;  3UGD A;  1YU6 C;  1TIH A;  5FUV A;  2QQC A;  2J9R A;  1KBE A;  4FKD A;  1SGD I;  1DS2 I;  1TBQ R;  1UHA A;  1W3S A;  1CSO I;  2X52 A;  1CE3 A;  3HH2 C;  1UUC A;  1TBN A;  2NU4 I;  2LUY A;  2SGP I;  3RU0 A;  2E5R A;  1MJA A;  1PTR A;  2W0T A;  3TO7 A;  1YTP A;  3OVO A;  3B4V C;  1IW4 A;  2GIV A;  1SGE I;  5HQ8 A;  2DB6 A;  2V1C A;  2ORV A;  1SGP I;  1AN1 I;  4E1R A;  1OYV I;  1TUR A;  1WKX A;  1U5K A;  1PTQ A;  1KMA A;  2JW6 A;  3BJI A;  2DKV A;  9WGA A;  2JXD A;  3MEK A;  2JA1 A;  3TO9 A;  1PJU A;  1K7V A;  2B0U C;  2F3C I;  3R5D A;  5FUW A;  2N17 A;  1Z2I A;  1MJB A;  3E59 A;  5E3P A;  5HI7 A;  1FAR A;  2QQ0 A;  1SGY I;  1ULM A;  2ELI A;  2ENN A;  2K9H A;  3OXF A;  5EX3 A;  2NU0 I;  1OMU A;  2JYY A;  2QQD A;  2SGD I;  2ORW A;  2Y0M A;  2KMQ A;  2N52 A;  1SGQ I;  2B8T A;  4OVO A;  5E3Q A;  2KCX A;  3UEY A;  2A20 A;  1V1H A;  4SGB I;  2GKT I;  1K7T A;  1TBR R;  1K7U A;  2GVI A;  3E2I A;  1R79 A;  3VDP A;  2ARP F;  2KMR A;  4HGU A;  1DS3 I;  3PDN A;  3SGB I;  3UGL A;  2OD1 A;  1BUS A;  2XRC A;  2WCY A;  3R5A A;  1PPF I;  2NU1 I;  3QAH A;  4UXJ A;  3D00 A;  1XX6 A;  1CHO I;  2X3T A;  3SEK C;  1LR9 A;  4UXI A;  5EX0 A;  1M8C A;  3FSX A;  1CT0 I;  1OMT A;  1TUS A;  2E73 A;  3KY9 A;  4WP4 A;  3QTL D;  2N71 A;  1WGC A;  3VE5 A;  1HJA I;  3CXL A;  2KMO A;  3R5C A;  3VDU A;  2M5X A;  1V1I A;  4E1P A;  1HEV A;  1FYB A;  1NUB A;  1H0Z A;  5FUY A;  3UEJ A;  1MT1 A;  2ROW A;  3TOA A;  2V1C C;  1KBF A;  1CGJ I;  1Y1B A;  3TOB A;  3UOE A;  1TBO A;  2OZU A;  2OU2 A;  5J8F A;  2J87 A;  1XA6 A;  1S20 A;  2GKV A;  3OXL A;  1HDL A;  1OVO A;  1VDD A;  1CT2 I;  1SGN I;  1W4R A;  1NXU A;  2CWF A;  2LEO A;  2ODD A;  3QWP A;  1SGR I;  1P9G A;  2V53 A;  1BMO A;  2GKR I;  2RC4 A;  3R5B A;  3GOX A;  2WVJ A;  2YUU A;  1CGI I;  1M8B A;  1RFH A;  1UVG A;  1ULK A;  1UVF A;  1WTJ A;  2N1A B;  1N13 A;  2NU2 I; 
#chains in the Genus database with same CATH homology
 4JCV E;  2L8E A;  1IY6 A;  3UGI A;  4L9M A;  1X74 A;  2JZM A;  4B6D A;  2QPO A;  5CCL A;  5JHW C;  1FAQ A;  2OVO A;  2QQE A;  2SGF I;  2UZ3 A;  1Y8F A;  5DAE A;  4GI3 C;  2NU3 I;  3FC3 A;  2ENZ A;  1HPT A;  2SGE I;  4UXH A;  1CT4 I;  4A24 A;  3OXG A;  1PCE A;  1XBT A;  1IY5 A;  1LR8 A;  1R0R I;  2BUS A;  1Y1C A;  1TGS I;  1LR7 A;  2YQP A;  2SGQ I;  2ERW A;  5FUX A;  2KMP A;  2FNF X;  3OL0 A;  2L7X A;  2P6A C;  2CJS C;  1Z7K B;  3UFF A;  1X4S A;  2DIP A;  3SGQ I;  5CCM A;  1TOT A;  3TJQ A;  2VRW B;  3UGD A;  1YU6 C;  1TIH A;  5FUV A;  2QQC A;  2J9R A;  1KBE A;  4FKD A;  1SGD I;  1DS2 I;  1TBQ R;  1W3S A;  1CSO I;  1CE3 A;  3HH2 C;  1UUC A;  1TBN A;  2NU4 I;  2LUY A;  2SGP I;  3RU0 A;  2E5R A;  1PTR A;  2W0T A;  1YTP A;  3OVO A;  3B4V C;  1IW4 A;  1SGE I;  5HQ8 A;  2DB6 A;  2V1C A;  2ORV A;  1SGP I;  1AN1 I;  4E1R A;  1OYV I;  1TUR A;  1U5K A;  1PTQ A;  1KMA A;  2JW6 A;  3BJI A;  2JXD A;  3MEK A;  2JA1 A;  2B0U C;  1PJU A;  2F3C I;  5FUW A;  5HI7 A;  2N17 A;  3E59 A;  1FAR A;  2QQ0 A;  1SGY I;  3OXF A;  2ELI A;  2ENN A;  2K9H A;  5EX3 A;  2NU0 I;  1OMU A;  2JYY A;  2QQD A;  2SGD I;  2ORW A;  4OVO A;  2KMQ A;  2N52 A;  1SGQ I;  2B8T A;  3UEY A;  2KCX A;  2A20 A;  1V1H A;  4SGB I;  2GKT I;  1TBR R;  2GVI A;  3E2I A;  1R79 A;  3VDP A;  2ARP F;  2KMR A;  4HGU A;  1DS3 I;  3UGL A;  3SGB I;  1BUS A;  2OD1 A;  2XRC A;  2WCY A;  1PPF I;  2NU1 I;  3SEK C;  4UXJ A;  3D00 A;  1XX6 A;  1CHO I;  1LR9 A;  4UXI A;  5EX0 A;  1M8C A;  1CT0 I;  1OMT A;  1TUS A;  2E73 A;  3KY9 A;  3QTL D;  2N71 A;  3VE5 A;  1HJA I;  3CXL A;  2KMO A;  3VDU A;  2M5X A;  1V1I A;  4E1P A;  1FYB A;  1NUB A;  1H0Z A;  5FUY A;  3UEJ A;  1MT1 A;  2ROW A;  2V1C C;  1KBF A;  1CGJ I;  1Y1B A;  1TBO A;  2J87 A;  1XA6 A;  2GKV A;  1HDL A;  3OXL A;  1OVO A;  1VDD A;  1CT2 I;  1SGN I;  1W4R A;  2ODD A;  2LEO A;  3QWP A;  1SGR I;  2V53 A;  1BMO A;  2GKR I;  3GOX A;  2WVJ A;  2YUU A;  1CGI I;  1M8B A;  1RFH A;  1UVG A;  1UVF A;  3PDN A;  2N1A B;  1N13 A;  2NU2 I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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