2L8EA

Solution nmr structure of fcs domain of human polyhomeotic homolog 1 (hph1)
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
49
structure length
49
Chain Sequence
GTRGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title 1H, 15N and 13C assigned chemical shifts of FCS domain from human polyhomeotic homolog 1
rcsb
molecule tags Dna binding protein
source organism Homo sapiens
molecule keywords Polyhomeotic-like protein 1
total genus 9
structure length 49
sequence length 49
ec nomenclature
pdb deposition date 2011-01-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.160 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2l8eA00
2L8EA 2W0TA
chains in the Genus database with same CATH superfamily
2PQ8A 1TURA 1OYVI 1V1HA 2WCYA 3D00A 3HH2C 1WKXA 5DAEA 1WGCA 3SGBI 5EX0A 5JHWC 1DS2I 1Z2IA 2OVOA 2WVJA 2CWHA 4WP4A 3VDUA 2ODDA 2X52A 5CCLA 2QQCA 1Q9BA 2LUYA 1YU6C 2WGCA 3VDPA 2CJSC 1PCEA 2ORWA 4SGBI 1Z7KB 3R5CA 1AN1I 4HGUA 1KBFA 1TBNA 2N52A 1OMUA 2SGEI 1IY5A 2JYYA 3TJQA 3R5AA 3SGQI 2NU4I 4E1RA 2ELIA 1R79A 1IY6A 2M5XA 1HPTA 2UZ3A 2K9HA 1KBEA 5J8FA 1IW4A 1LR9A 2LB7A 3UOEA 1CHOI 1CT2I 2VRWB 4OVOA 3TOAA 2X3TA 1U5KA 4DNCA 1PJUA 1YTPA 2DKVA 1BUSA 1P9GA 1FAQA 5FUYA 2FNFX 1SGEI 1UUCA 2L7XA 3E2IA 2L8EA 2N1AB 1W3SA 2QPOA 3UEJA 1MT1A 1K7VA 2GKVA 3QAHA 1XX6A 2B8TA 2Y0MA 2J9RA 1SGDI 1UHAA 1HDLA 3FSYA 3RU0A 1Y1BA 1MJAA 1NUBA 3KY9A 1FYBA 3R5DA 4UXIA 3UEYA 4B6DA 2SGDI 2J87A 1VDDA 1P9ZA 2V53A 4L9MA 1X74A 3FSXA 1S20A 1WGTA 3UGDA 3GOXA 1FARA 2LEOA 3R5BA 4AMLA 1KMAA 2ENNA 1UVGA 3UGLA 3OXLA 9WGAA 2W0TA 1CE3A 1CGII 3UFFA 1OMTA 4A24A 2QQ0A 3TO9A 3OL0A 2KMPA 1HJAI 1SGQI 1TBOA 5FUWA 3SEKC 3FC3A 4JCVE 1TBQR 2QQDA 2KCXA 1FY7A 3B4VC 1MJ9A 1DS3I 1SGYI 2N17A 2ROWA 2RC4A 2OZUA 1Y1CA 3E59A 2NU1I 1CT4I 1CT0I 2GKTI 1CGJI 1MJBA 1K7UA 1SGNI 1V1IA 1CSOI 2E73A 2JXDA 5J8CA 1XBTA 2A20A 2DIPA 5E3QA 1SGPI 2BUSA 1PTRA 2CWFA 2GVIA 5FUVA 1M8CA 1PPFI 1SGRI 1TOTA 1WTJA 2ARPF 1K7TA 2N71A 2SGPI 5E3RA 1RFHA 2DB6A 2SGFI 3OXGA 3QTLD 2ERWA 5EX3A 3TO6A 3UGIA 4UXHA 4GI3C 2B0UC 2KMQA 5E3PA 2OU2A 1TGSI 1LR8A 3OXFA 3PDNA 2YUUA 1TBRR 2RIJA 1ULNA 1TUSA 4FKDA 5FUXA 2V1CC 1ULKA 3OVOA 3TOBA 2NU2I 3CXLA 5HQ8A 1NXUA 2ORVA 2QQEA 2JW6A 2SGQI 1W4RA 1BMOA 2GKRI 2OD1A 1XA6A 2F3CI 1H0ZA 2NU3I 2ENZA 1OVOA 3MEKA 3VE5A 1HEVA 3QWPA 2UVOA 4MPIA 2P6AC 1ULMA 2V1CA 3TO7A 2XRCA 5HI7A 3BJIA 2NU0I 1R0RI 1TIHA 2E5RA 2JA1A 2KMOA 4E1PA 5CCMA 1M8BA 1PTQA 2KMRA 1Y8FA 2GIVA 2CWGA 7WGAA 4UXJA 2JZMA 1N13A 1X4SA 2YQPA 1UVFA 1LR7A
chains in the Genus database with same CATH topology
1TURA 1OYVI 1V1HA 2WCYA 3D00A 3HH2C 5DAEA 3SGBI 1DS2I 2OVOA 2WVJA 3VDUA 2ODDA 5CCLA 2QQCA 2LUYA 1YU6C 3VDPA 2CJSC 1PCEA 2ORWA 4SGBI 1Z7KB 1AN1I 4HGUA 1KBFA 1TBNA 2N52A 1OMUA 2SGEI 1IY5A 2JYYA 3TJQA 3SGQI 2NU4I 4E1RA 2ELIA 1R79A 1IY6A 2M5XA 1HPTA 2UZ3A 2K9HA 1KBEA 1IW4A 1LR9A 1CHOI 1CT2I 2VRWB 4OVOA 1U5KA 1PJUA 1YTPA 1BUSA 1FAQA 5FUYA 2FNFX 1SGEI 1UUCA 2L7XA 3E2IA 2L8EA 2N1AB 1W3SA 2QPOA 3UEJA 1MT1A 2GKVA 1XX6A 2B8TA 2J9RA 1SGDI 1HDLA 3RU0A 1Y1BA 1NUBA 3KY9A 1FYBA 4UXIA 3UEYA 4B6DA 2SGDI 2J87A 1VDDA 2V53A 4L9MA 3GOXA 1X74A 3UGDA 1FARA 2LEOA 1KMAA 2ENNA 1UVGA 3UGLA 3OXLA 2W0TA 1CE3A 1CGII 3UFFA 1OMTA 4A24A 2QQ0A 3OL0A 2KMPA 1HJAI 1SGQI 1TBOA 5FUWA 3SEKC 3FC3A 4JCVE 1TBQR 2QQDA 2KCXA 3B4VC 1DS3I 1SGYI 2N17A 2ROWA 1Y1CA 3E59A 2NU1I 1CT4I 1CT0I 2GKTI 1CGJI 1V1IA 1SGNI 1CSOI 2E73A 2JXDA 1XBTA 2A20A 2DIPA 1SGPI 2BUSA 1PTRA 2GVIA 5FUVA 5JHWC 1M8CA 1PPFI 1SGRI 1TOTA 2ARPF 2N71A 5EX0A 2SGPI 5FUXA 1RFHA 2DB6A 2SGFI 3OXGA 3QTLD 2ERWA 5EX3A 3UGIA 4UXHA 4GI3C 2B0UC 2KMQA 3OXFA 1TGSI 1LR8A 3PDNA 2YUUA 1TBRR 1TUSA 4FKDA 2V1CC 3OVOA 2NU2I 3CXLA 5HQ8A 2ORVA 2QQEA 2JW6A 2SGQI 1W4RA 1BMOA 2GKRI 2OD1A 1XA6A 2F3CI 1H0ZA 2NU3I 2ENZA 1OVOA 3MEKA 3VE5A 3QWPA 2P6AC 2V1CA 2XRCA 5HI7A 3BJIA 2NU0I 1R0RI 1TIHA 2E5RA 2JA1A 2KMOA 4E1PA 5CCMA 1M8BA 1PTQA 2KMRA 1Y8FA 4UXJA 2JZMA 1N13A 1X4SA 2YQPA 1UVFA 1LR7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L8E A;  2W0T A; 
#chains in the Genus database with same CATH topology
 2PQ8 A;  1TUR A;  1OYV I;  1V1H A;  2WCY A;  3D00 A;  3HH2 C;  1WKX A;  5DAE A;  1WGC A;  3SGB I;  5EX0 A;  5JHW C;  1DS2 I;  1Z2I A;  2OVO A;  2WVJ A;  2CWH A;  4WP4 A;  3VDU A;  2ODD A;  2X52 A;  5CCL A;  2QQC A;  1Q9B A;  2LUY A;  1YU6 C;  2WGC A;  3VDP A;  2CJS C;  1PCE A;  2ORW A;  4SGB I;  1Z7K B;  3R5C A;  1AN1 I;  4HGU A;  1KBF A;  1TBN A;  2N52 A;  1OMU A;  2SGE I;  1IY5 A;  2JYY A;  3TJQ A;  3R5A A;  3SGQ I;  2NU4 I;  4E1R A;  2ELI A;  1R79 A;  1IY6 A;  2M5X A;  1HPT A;  2UZ3 A;  2K9H A;  1KBE A;  5J8F A;  1IW4 A;  1LR9 A;  2LB7 A;  3UOE A;  1CHO I;  1CT2 I;  2VRW B;  4OVO A;  3TOA A;  2X3T A;  1U5K A;  4DNC A;  1PJU A;  1YTP A;  2DKV A;  1BUS A;  1P9G A;  1FAQ A;  5FUY A;  2FNF X;  1SGE I;  1UUC A;  2L7X A;  3E2I A;  2L8E A;  2N1A B;  1W3S A;  2QPO A;  3UEJ A;  1MT1 A;  1K7V A;  2GKV A;  3QAH A;  1XX6 A;  2B8T A;  2Y0M A;  2J9R A;  1SGD I;  1UHA A;  1HDL A;  3FSY A;  3RU0 A;  1Y1B A;  1MJA A;  1NUB A;  3KY9 A;  1FYB A;  3R5D A;  4UXI A;  3UEY A;  4B6D A;  2SGD I;  2J87 A;  1VDD A;  1P9Z A;  2V53 A;  4L9M A;  1X74 A;  3FSX A;  1S20 A;  1WGT A;  3UGD A;  3GOX A;  1FAR A;  2LEO A;  3R5B A;  4AML A;  1KMA A;  2ENN A;  1UVG A;  3UGL A;  3OXL A;  9WGA A;  2W0T A;  1CE3 A;  1CGI I;  3UFF A;  1OMT A;  4A24 A;  2QQ0 A;  3TO9 A;  3OL0 A;  2KMP A;  1HJA I;  1SGQ I;  1TBO A;  5FUW A;  3SEK C;  3FC3 A;  4JCV E;  1TBQ R;  2QQD A;  2KCX A;  1FY7 A;  3B4V C;  1MJ9 A;  1DS3 I;  1SGY I;  2N17 A;  2ROW A;  2RC4 A;  2OZU A;  1Y1C A;  3E59 A;  2NU1 I;  1CT4 I;  1CT0 I;  2GKT I;  1CGJ I;  1MJB A;  1K7U A;  1SGN I;  1V1I A;  1CSO I;  2E73 A;  2JXD A;  5J8C A;  1XBT A;  2A20 A;  2DIP A;  5E3Q A;  1SGP I;  2BUS A;  1PTR A;  2CWF A;  2GVI A;  5FUV A;  1M8C A;  1PPF I;  1SGR I;  1TOT A;  1WTJ A;  2ARP F;  1K7T A;  2N71 A;  2SGP I;  5E3R A;  1RFH A;  2DB6 A;  2SGF I;  3OXG A;  3QTL D;  2ERW A;  5EX3 A;  3TO6 A;  3UGI A;  4UXH A;  4GI3 C;  2B0U C;  2KMQ A;  5E3P A;  2OU2 A;  1TGS I;  1LR8 A;  3OXF A;  3PDN A;  2YUU A;  1TBR R;  2RIJ A;  1ULN A;  1TUS A;  4FKD A;  5FUX A;  2V1C C;  1ULK A;  3OVO A;  3TOB A;  2NU2 I;  3CXL A;  5HQ8 A;  1NXU A;  2ORV A;  2QQE A;  2JW6 A;  2SGQ I;  1W4R A;  1BMO A;  2GKR I;  2OD1 A;  1XA6 A;  2F3C I;  1H0Z A;  2NU3 I;  2ENZ A;  1OVO A;  3MEK A;  3VE5 A;  1HEV A;  3QWP A;  2UVO A;  4MPI A;  2P6A C;  1ULM A;  2V1C A;  3TO7 A;  2XRC A;  5HI7 A;  3BJI A;  2NU0 I;  1R0R I;  1TIH A;  2E5R A;  2JA1 A;  2KMO A;  4E1P A;  5CCM A;  1M8B A;  1PTQ A;  2KMR A;  1Y8F A;  2GIV A;  2CWG A;  7WGA A;  4UXJ A;  2JZM A;  1N13 A;  1X4S A;  2YQP A;  1UVF A;  1LR7 A; 
#chains in the Genus database with same CATH homology
 1TUR A;  1OYV I;  1V1H A;  2WCY A;  3D00 A;  3HH2 C;  5DAE A;  3SGB I;  1DS2 I;  2OVO A;  2WVJ A;  3VDU A;  2ODD A;  5CCL A;  2QQC A;  2LUY A;  1YU6 C;  3VDP A;  2CJS C;  1PCE A;  2ORW A;  4SGB I;  1Z7K B;  1AN1 I;  4HGU A;  1KBF A;  1TBN A;  2N52 A;  1OMU A;  2SGE I;  1IY5 A;  2JYY A;  3TJQ A;  3SGQ I;  2NU4 I;  4E1R A;  2ELI A;  1R79 A;  1IY6 A;  2M5X A;  1HPT A;  2UZ3 A;  2K9H A;  1KBE A;  1IW4 A;  1LR9 A;  1CHO I;  1CT2 I;  2VRW B;  4OVO A;  1U5K A;  1PJU A;  1YTP A;  1BUS A;  1FAQ A;  5FUY A;  2FNF X;  1SGE I;  1UUC A;  2L7X A;  3E2I A;  2L8E A;  2N1A B;  1W3S A;  2QPO A;  3UEJ A;  1MT1 A;  2GKV A;  1XX6 A;  2B8T A;  2J9R A;  1SGD I;  1HDL A;  3RU0 A;  1Y1B A;  1NUB A;  3KY9 A;  1FYB A;  4UXI A;  3UEY A;  4B6D A;  2SGD I;  2J87 A;  1VDD A;  2V53 A;  4L9M A;  3GOX A;  1X74 A;  3UGD A;  1FAR A;  2LEO A;  1KMA A;  2ENN A;  1UVG A;  3UGL A;  3OXL A;  2W0T A;  1CE3 A;  1CGI I;  3UFF A;  1OMT A;  4A24 A;  2QQ0 A;  3OL0 A;  2KMP A;  1HJA I;  1SGQ I;  1TBO A;  5FUW A;  3SEK C;  3FC3 A;  4JCV E;  1TBQ R;  2QQD A;  2KCX A;  3B4V C;  1DS3 I;  1SGY I;  2N17 A;  2ROW A;  1Y1C A;  3E59 A;  2NU1 I;  1CT4 I;  1CT0 I;  2GKT I;  1CGJ I;  1V1I A;  1SGN I;  1CSO I;  2E73 A;  2JXD A;  1XBT A;  2A20 A;  2DIP A;  1SGP I;  2BUS A;  1PTR A;  2GVI A;  5FUV A;  5JHW C;  1M8C A;  1PPF I;  1SGR I;  1TOT A;  2ARP F;  2N71 A;  5EX0 A;  2SGP I;  5FUX A;  1RFH A;  2DB6 A;  2SGF I;  3OXG A;  3QTL D;  2ERW A;  5EX3 A;  3UGI A;  4UXH A;  4GI3 C;  2B0U C;  2KMQ A;  3OXF A;  1TGS I;  1LR8 A;  3PDN A;  2YUU A;  1TBR R;  1TUS A;  4FKD A;  2V1C C;  3OVO A;  2NU2 I;  3CXL A;  5HQ8 A;  2ORV A;  2QQE A;  2JW6 A;  2SGQ I;  1W4R A;  1BMO A;  2GKR I;  2OD1 A;  1XA6 A;  2F3C I;  1H0Z A;  2NU3 I;  2ENZ A;  1OVO A;  3MEK A;  3VE5 A;  3QWP A;  2P6A C;  2V1C A;  2XRC A;  5HI7 A;  3BJI A;  2NU0 I;  1R0R I;  1TIH A;  2E5R A;  2JA1 A;  2KMO A;  4E1P A;  5CCM A;  1M8B A;  1PTQ A;  2KMR A;  1Y8F A;  4UXJ A;  2JZM A;  1N13 A;  1X4S A;  2YQP A;  1UVF A;  1LR7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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