2LEOA

Solution structure of esophageal cancer-related gene 2
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
66
structure length
66
Chain Sequence
SEAASLSPKKVDCSIYKKYPVVAIPCPITYLPVCGSDYITYGNECHLCTESLKSNGRVQFLHDGSC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NMR structure note: human esophageal cancer-related gene 2
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Homo sapiens
molecule keywords Serine protease inhibitor Kazal-type 7
total genus 14
structure length 66
sequence length 66
ec nomenclature
pdb deposition date 2011-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2leoA00
4HGUA 5DAEA 1HJAI 2SGEI 1TBQR 1TBRR 2GKRI 2B0UC 1MT1A 2N17A 2QQDA 1IY6A 1SGYI 3SEKC 2KCXA 1AN1I 1CT4I 1UVGA 1IW4A 3TJQA 2QQCA 2JZMA 2NU4I 5JHWC 1CT2I 3QTLD 4SGBI 2BUSA 1N13A 3SGBI 1TURA 2M5XA 1PJUA 1Z7KB 2SGDI 1SGRI 2ARPF 1TUSA 1OYVI 3HH2C 4GI3C 1UVFA 2GKTI 2N52A 1FYBA 1Y1CA 2GKVA 2JXDA 1SGEI 2LEOA 2KMPA 1LR8A 1PPFI 3B4VC 4OVOA 1KMAA 2NU2I 1YU6C 2KMOA 1Y1BA 2OVOA 2JYYA 2WCYA 1R0RI 1CT0I 1H0ZA 1YTPA 1DS3I 2SGPI 1IY5A 2NU1I 2XRCA 1PCEA 1CE3A 1HDLA 1CGII 2KMQA 1M8BA 1BMOA 2NU0I 1DS2I 1LR7A 1NUBA 1BUSA 1SGNI 1SGQI 1UUCA 2SGQI 1SGDI 2P6AC 1OVOA 1OMTA 1CGJI 2F3CI 2KMRA 2N71A 1OMUA 3OVOA 1TIHA 2NU3I 1CSOI 1CHOI 2SGFI 1LR9A 1HPTA 1SGPI 3SGQI 1M8CA 2V53A 1TGSI 2ERWA
chains in the Genus database with same CATH superfamily
5EX0A 2OU2A 3TO6A 3BJIA 2CWGA 4HGUA 5DAEA 3KY9A 1HJAI 2SGEI 3VDPA 1TBQR 1TBRR 2GKRI 2JA1A 2B0UC 5E3PA 1MT1A 1KBFA 3VDUA 2N17A 1TOTA 2QQDA 2VRWB 2RC4A 1IY6A 1SGYI 2DKVA 3SEKC 2KCXA 1WGTA 1ULKA 2B8TA 2GVIA 5FUYA 3TOAA 2X52A 2GIVA 1AN1I 1Z2IA 3UGDA 1CT4I 3R5AA 1UVGA 2K9HA 1IW4A 2QQ0A 3TJQA 2QQCA 5FUXA 2JZMA 1PTQA 4WP4A 1WKXA 2NU4I 3UFFA 1P9GA 5JHWC 2E5RA 1K7VA 3TO9A 1CT2I 1S20A 2ODDA 3QTLD 4SGBI 3RU0A 1XX6A 2W0TA 2BUSA 1N13A 4UXJA 4A24A 1Y8FA 2ELIA 3MEKA 4DNCA 3OXFA 4JCVE 1Q9BA 1TURA 3SGBI 2M5XA 2X3TA 1PJUA 1ULNA 1Z7KB 1SGRI 1ULMA 2ARPF 1TUSA 2ORVA 1OYVI 2SGDI 5E3QA 3HH2C 4GI3C 1UVFA 2GKTI 5EX3A 4UXIA 4E1PA 2J9RA 3PDNA 3E59A 1FY7A 1MJBA 7WGAA 1KBEA 2N52A 1Y1CA 1FYBA 2DIPA 1XBTA 2LUYA 2GKVA 2V1CA 2JXDA 2QPOA 2V1CC 1SGEI 4FKDA 3QAHA 3GOXA 2LEOA 2KMPA 3TO7A 1W4RA 1LR8A 1PPFI 3B4VC 4OVOA 1KMAA 2NU2I 4AMLA 1X4SA 1YU6C 9WGAA 2KMOA 3VE5A 5J8FA 2ORWA 2QQEA 1P9ZA 1Y1BA 2FNFX 2OVOA 2JYYA 2UVOA 2ENZA 1V1HA 2N1AB 2WCYA 2J87A 1R0RI 3FSXA 3R5DA 1CT0I 2RIJA 5CCMA 1WTJA 1HEVA 1VDDA 2L7XA 1X74A 1H0ZA 3UEYA 5CCLA 1PTRA 1RFHA 1DS3I 1YTPA 1NXUA 2SGPI 2OZUA 3E2IA 4E1RA 5J8CA 1MJAA 4B6DA 1IY5A 2UZ3A 3D00A 2NU1I 2XRCA 5HI7A 1PCEA 1FARA 1K7TA 5FUWA 1K7UA 2CWFA 1CE3A 2PQ8A 1HDLA 1UHAA 1CGII 2KMQA 1W3SA 1FAQA 1M8BA 1BMOA 2OD1A 2DB6A 3TOBA 3UEJA 1R79A 3FC3A 2NU0I 1XA6A 3FSYA 3CXLA 1DS2I 1LR7A 1NUBA 2ERWA 4UXHA 2Y0MA 1BUSA 2ENNA 2E73A 2CWHA 1SGNI 1SGQI 3R5BA 1MJ9A 1UUCA 2SGQI 3UOEA 5HQ8A 1SGDI 2YQPA 2P6AC 1OVOA 1OMTA 1TBNA 3QWPA 1CGJI 1TBOA 2F3CI 2KMRA 3OXLA 5E3RA 3R5CA 1V1IA 2N71A 4MPIA 1OMUA 3OVOA 1TIHA 2NU3I 3OXGA 2WGCA 2YUUA 1CSOI 1CHOI 2JW6A 1U5KA 1LR9A 1WGCA 1HPTA 1SGPI 2SGFI 2WVJA 3SGQI 2L8EA 2LB7A 3OL0A 4L9MA 5FUVA 3UGIA 1M8CA 2V53A 1TGSI 3UGLA 2A20A 2CJSC 2ROWA
chains in the Genus database with same CATH topology
5EX0A 3BJIA 4HGUA 5DAEA 3KY9A 1HJAI 2SGEI 3VDPA 1TBQR 1TBRR 2GKRI 2JA1A 2B0UC 1MT1A 1KBFA 3VDUA 2N17A 1TOTA 2QQDA 2VRWB 1IY6A 1SGYI 3SEKC 2KCXA 2GVIA 5FUYA 2B8TA 1AN1I 3UGDA 1CT4I 1UVGA 2K9HA 1IW4A 2QQ0A 3TJQA 2QQCA 5FUXA 2JZMA 1PTQA 2NU4I 3UFFA 5JHWC 2E5RA 1CT2I 2ODDA 3QTLD 4SGBI 3RU0A 1XX6A 2W0TA 2BUSA 1N13A 4UXJA 4A24A 1Y8FA 2ELIA 3MEKA 3OXFA 4JCVE 3SGBI 1TURA 2M5XA 1PJUA 1Z7KB 2SGDI 1SGRI 5FUWA 2ARPF 1TUSA 2ORVA 1OYVI 3HH2C 4GI3C 1UVFA 2GKTI 4UXIA 4E1PA 2J9RA 3PDNA 3E59A 1KBEA 2N52A 1Y1CA 1FYBA 2DIPA 1XBTA 2LUYA 2GKVA 2V1CA 2JXDA 2QPOA 2V1CC 1SGEI 4FKDA 3GOXA 2LEOA 2KMPA 1W4RA 1LR8A 1PPFI 3B4VC 4OVOA 1KMAA 2NU2I 1X4SA 1YU6C 2KMOA 3VE5A 2ORWA 2QQEA 1Y1BA 2FNFX 2OVOA 2JYYA 2WCYA 2ENZA 1V1HA 2N1AB 5EX3A 2J87A 1R0RI 1CT0I 5CCMA 1VDDA 2L7XA 1X74A 1H0ZA 3UEYA 5CCLA 1PTRA 1RFHA 1DS3I 1YTPA 2SGPI 3E2IA 4E1RA 1IY5A 4B6DA 2UZ3A 3D00A 2NU1I 2XRCA 5HI7A 1PCEA 1FARA 1CE3A 1HDLA 1CGII 2KMQA 1W3SA 1FAQA 1M8BA 1BMOA 2OD1A 2DB6A 3UEJA 1R79A 3FC3A 2NU0I 1XA6A 3CXLA 1DS2I 1LR7A 1NUBA 2ERWA 4UXHA 1BUSA 2ENNA 2E73A 1SGNI 1SGQI 1UUCA 5HQ8A 2SGQI 1SGDI 2YQPA 2P6AC 1OVOA 1OMTA 1TBNA 3QWPA 1CGJI 1TBOA 2F3CI 2KMRA 3OXLA 1V1IA 2N71A 1OMUA 3OVOA 1TIHA 2NU3I 3OXGA 2YUUA 1CSOI 1CHOI 2JW6A 1U5KA 1LR9A 2SGFI 1HPTA 1SGPI 2WVJA 3SGQI 3UGIA 2L8EA 4L9MA 3OL0A 5FUVA 1M8CA 2V53A 1TGSI 3UGLA 2A20A 2CJSC 2ROWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HGU A;  5DAE A;  1HJA I;  2SGE I;  1TBQ R;  1TBR R;  2GKR I;  2B0U C;  1MT1 A;  2N17 A;  2QQD A;  1IY6 A;  1SGY I;  3SEK C;  2KCX A;  1AN1 I;  1CT4 I;  1UVG A;  1IW4 A;  3TJQ A;  2QQC A;  2JZM A;  2NU4 I;  5JHW C;  1CT2 I;  3QTL D;  4SGB I;  2BUS A;  1N13 A;  3SGB I;  1TUR A;  2M5X A;  1PJU A;  1Z7K B;  2SGD I;  1SGR I;  2ARP F;  1TUS A;  1OYV I;  3HH2 C;  4GI3 C;  1UVF A;  2GKT I;  2N52 A;  1FYB A;  1Y1C A;  2GKV A;  2JXD A;  1SGE I;  2LEO A;  2KMP A;  1LR8 A;  1PPF I;  3B4V C;  4OVO A;  1KMA A;  2NU2 I;  1YU6 C;  2KMO A;  1Y1B A;  2OVO A;  2JYY A;  2WCY A;  1R0R I;  1CT0 I;  1H0Z A;  1YTP A;  1DS3 I;  2SGP I;  1IY5 A;  2NU1 I;  2XRC A;  1PCE A;  1CE3 A;  1HDL A;  1CGI I;  2KMQ A;  1M8B A;  1BMO A;  2NU0 I;  1DS2 I;  1LR7 A;  1NUB A;  1BUS A;  1SGN I;  1SGQ I;  1UUC A;  2SGQ I;  1SGD I;  2P6A C;  1OVO A;  1OMT A;  1CGJ I;  2F3C I;  2KMR A;  2N71 A;  1OMU A;  3OVO A;  1TIH A;  2NU3 I;  1CSO I;  1CHO I;  2SGF I;  1LR9 A;  1HPT A;  1SGP I;  3SGQ I;  1M8C A;  2V53 A;  1TGS I;  2ERW A; 
#chains in the Genus database with same CATH topology
 5EX0 A;  2OU2 A;  3TO6 A;  3BJI A;  2CWG A;  4HGU A;  5DAE A;  3KY9 A;  1HJA I;  2SGE I;  3VDP A;  1TBQ R;  1TBR R;  2GKR I;  2JA1 A;  2B0U C;  5E3P A;  1MT1 A;  1KBF A;  3VDU A;  2N17 A;  1TOT A;  2QQD A;  2VRW B;  2RC4 A;  1IY6 A;  1SGY I;  2DKV A;  3SEK C;  2KCX A;  1WGT A;  1ULK A;  2B8T A;  2GVI A;  5FUY A;  3TOA A;  2X52 A;  2GIV A;  1AN1 I;  1Z2I A;  3UGD A;  1CT4 I;  3R5A A;  1UVG A;  2K9H A;  1IW4 A;  2QQ0 A;  3TJQ A;  2QQC A;  5FUX A;  2JZM A;  1PTQ A;  4WP4 A;  1WKX A;  2NU4 I;  3UFF A;  1P9G A;  5JHW C;  2E5R A;  1K7V A;  3TO9 A;  1CT2 I;  1S20 A;  2ODD A;  3QTL D;  4SGB I;  3RU0 A;  1XX6 A;  2W0T A;  2BUS A;  1N13 A;  4UXJ A;  4A24 A;  1Y8F A;  2ELI A;  3MEK A;  4DNC A;  3OXF A;  4JCV E;  1Q9B A;  1TUR A;  3SGB I;  2M5X A;  2X3T A;  1PJU A;  1ULN A;  1Z7K B;  1SGR I;  1ULM A;  2ARP F;  1TUS A;  2ORV A;  1OYV I;  2SGD I;  5E3Q A;  3HH2 C;  4GI3 C;  1UVF A;  2GKT I;  5EX3 A;  4UXI A;  4E1P A;  2J9R A;  3PDN A;  3E59 A;  1FY7 A;  1MJB A;  7WGA A;  1KBE A;  2N52 A;  1Y1C A;  1FYB A;  2DIP A;  1XBT A;  2LUY A;  2GKV A;  2V1C A;  2JXD A;  2QPO A;  2V1C C;  1SGE I;  4FKD A;  3QAH A;  3GOX A;  2LEO A;  2KMP A;  3TO7 A;  1W4R A;  1LR8 A;  1PPF I;  3B4V C;  4OVO A;  1KMA A;  2NU2 I;  4AML A;  1X4S A;  1YU6 C;  9WGA A;  2KMO A;  3VE5 A;  5J8F A;  2ORW A;  2QQE A;  1P9Z A;  1Y1B A;  2FNF X;  2OVO A;  2JYY A;  2UVO A;  2ENZ A;  1V1H A;  2N1A B;  2WCY A;  2J87 A;  1R0R I;  3FSX A;  3R5D A;  1CT0 I;  2RIJ A;  5CCM A;  1WTJ A;  1HEV A;  1VDD A;  2L7X A;  1X74 A;  1H0Z A;  3UEY A;  5CCL A;  1PTR A;  1RFH A;  1DS3 I;  1YTP A;  1NXU A;  2SGP I;  2OZU A;  3E2I A;  4E1R A;  5J8C A;  1MJA A;  4B6D A;  1IY5 A;  2UZ3 A;  3D00 A;  2NU1 I;  2XRC A;  5HI7 A;  1PCE A;  1FAR A;  1K7T A;  5FUW A;  1K7U A;  2CWF A;  1CE3 A;  2PQ8 A;  1HDL A;  1UHA A;  1CGI I;  2KMQ A;  1W3S A;  1FAQ A;  1M8B A;  1BMO A;  2OD1 A;  2DB6 A;  3TOB A;  3UEJ A;  1R79 A;  3FC3 A;  2NU0 I;  1XA6 A;  3FSY A;  3CXL A;  1DS2 I;  1LR7 A;  1NUB A;  2ERW A;  4UXH A;  2Y0M A;  1BUS A;  2ENN A;  2E73 A;  2CWH A;  1SGN I;  1SGQ I;  3R5B A;  1MJ9 A;  1UUC A;  2SGQ I;  3UOE A;  5HQ8 A;  1SGD I;  2YQP A;  2P6A C;  1OVO A;  1OMT A;  1TBN A;  3QWP A;  1CGJ I;  1TBO A;  2F3C I;  2KMR A;  3OXL A;  5E3R A;  3R5C A;  1V1I A;  2N71 A;  4MPI A;  1OMU A;  3OVO A;  1TIH A;  2NU3 I;  3OXG A;  2WGC A;  2YUU A;  1CSO I;  1CHO I;  2JW6 A;  1U5K A;  1LR9 A;  1WGC A;  1HPT A;  1SGP I;  2SGF I;  2WVJ A;  3SGQ I;  2L8E A;  2LB7 A;  3OL0 A;  4L9M A;  5FUV A;  3UGI A;  1M8C A;  2V53 A;  1TGS I;  3UGL A;  2A20 A;  2CJS C;  2ROW A; 
#chains in the Genus database with same CATH homology
 5EX0 A;  3BJI A;  4HGU A;  5DAE A;  3KY9 A;  1HJA I;  2SGE I;  3VDP A;  1TBQ R;  1TBR R;  2GKR I;  2JA1 A;  2B0U C;  1MT1 A;  1KBF A;  3VDU A;  2N17 A;  1TOT A;  2QQD A;  2VRW B;  1IY6 A;  1SGY I;  3SEK C;  2KCX A;  2GVI A;  5FUY A;  2B8T A;  1AN1 I;  3UGD A;  1CT4 I;  1UVG A;  2K9H A;  1IW4 A;  2QQ0 A;  3TJQ A;  2QQC A;  5FUX A;  2JZM A;  1PTQ A;  2NU4 I;  3UFF A;  5JHW C;  2E5R A;  1CT2 I;  2ODD A;  3QTL D;  4SGB I;  3RU0 A;  1XX6 A;  2W0T A;  2BUS A;  1N13 A;  4UXJ A;  4A24 A;  1Y8F A;  2ELI A;  3MEK A;  3OXF A;  4JCV E;  3SGB I;  1TUR A;  2M5X A;  1PJU A;  1Z7K B;  2SGD I;  1SGR I;  5FUW A;  2ARP F;  1TUS A;  2ORV A;  1OYV I;  3HH2 C;  4GI3 C;  1UVF A;  2GKT I;  4UXI A;  4E1P A;  2J9R A;  3PDN A;  3E59 A;  1KBE A;  2N52 A;  1Y1C A;  1FYB A;  2DIP A;  1XBT A;  2LUY A;  2GKV A;  2V1C A;  2JXD A;  2QPO A;  2V1C C;  1SGE I;  4FKD A;  3GOX A;  2LEO A;  2KMP A;  1W4R A;  1LR8 A;  1PPF I;  3B4V C;  4OVO A;  1KMA A;  2NU2 I;  1X4S A;  1YU6 C;  2KMO A;  3VE5 A;  2ORW A;  2QQE A;  1Y1B A;  2FNF X;  2OVO A;  2JYY A;  2WCY A;  2ENZ A;  1V1H A;  2N1A B;  5EX3 A;  2J87 A;  1R0R I;  1CT0 I;  5CCM A;  1VDD A;  2L7X A;  1X74 A;  1H0Z A;  3UEY A;  5CCL A;  1PTR A;  1RFH A;  1DS3 I;  1YTP A;  2SGP I;  3E2I A;  4E1R A;  1IY5 A;  4B6D A;  2UZ3 A;  3D00 A;  2NU1 I;  2XRC A;  5HI7 A;  1PCE A;  1FAR A;  1CE3 A;  1HDL A;  1CGI I;  2KMQ A;  1W3S A;  1FAQ A;  1M8B A;  1BMO A;  2OD1 A;  2DB6 A;  3UEJ A;  1R79 A;  3FC3 A;  2NU0 I;  1XA6 A;  3CXL A;  1DS2 I;  1LR7 A;  1NUB A;  2ERW A;  4UXH A;  1BUS A;  2ENN A;  2E73 A;  1SGN I;  1SGQ I;  1UUC A;  5HQ8 A;  2SGQ I;  1SGD I;  2YQP A;  2P6A C;  1OVO A;  1OMT A;  1TBN A;  3QWP A;  1CGJ I;  1TBO A;  2F3C I;  2KMR A;  3OXL A;  1V1I A;  2N71 A;  1OMU A;  3OVO A;  1TIH A;  2NU3 I;  3OXG A;  2YUU A;  1CSO I;  1CHO I;  2JW6 A;  1U5K A;  1LR9 A;  2SGF I;  1HPT A;  1SGP I;  2WVJ A;  3SGQ I;  3UGI A;  2L8E A;  4L9M A;  3OL0 A;  5FUV A;  1M8C A;  2V53 A;  1TGS I;  3UGL A;  2A20 A;  2CJS C;  2ROW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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