2NU4I

Accommodation of positively-charged residues in a hydrophobic specificity pocket: crystal structures of sgpb in complex with omtky3 variants lys18i and arg18i
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
51
structure length
51
Chain Sequence
VDCSEYPKPACTKEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
rcsb
molecule tags Hydrolase
source organism Meleagris gallopavo
molecule keywords Streptogrisin B, Proteinase B
total genus 14
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 2006-11-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2nu4I00
3QTLD 4SGBI 2KMPA 1HJAI 2NU3I 1Z7KB 1OMUA 3SEKC 3SGBI 2KMOA 1N13A 1Y1CA 2JZMA 1AN1I 1TBQR 2NU0I 1CHOI 1UUCA 2QQCA 2V53A 4HGUA 1CT0I 2SGEI 1SGEI 2JYYA 2N17A 1IY6A 1MT1A 1TGSI 2F3CI 1OYVI 3B4VC 1CGII 2GKRI 2SGFI 1DS3I 1DS2I 5DAEA 2B0UC 1CT4I 1UVFA 1CGJI 2WCYA 2ERWA 1KMAA 1YTPA 2GKVA 1OMTA 1BMOA 2P6AC 1UVGA 2KMQA 1LR9A 2N71A 1TUSA 2XRCA 1BUSA 1LR7A 2SGDI 2SGQI 3TJQA 1FYBA 1SGDI 1LR8A 2NU4I 2QQDA 1NUBA 5JHWC 1HDLA 1OVOA 2BUSA 1CT2I 2M5XA 1HPTA 1SGQI 1R0RI 1PCEA 1Y1BA 2NU1I 2N52A 4OVOA 2NU2I 1TURA 1SGRI 2SGPI 3HH2C 2KMRA 1CSOI 2KCXA 1TIHA 2JXDA 1H0ZA 3SGQI 1M8CA 1TBRR 2ARPF 1CE3A 1M8BA 1PPFI 3OVOA 1IW4A 1PJUA 1IY5A 1SGPI 2LEOA 2OVOA 1SGYI 1SGNI 2GKTI 1YU6C 4GI3C
chains in the Genus database with same CATH superfamily
1FY7A 3QTLD 4SGBI 3R5DA 2KMPA 1HJAI 1TBOA 3GOXA 2NU3I 1ULMA 1Z7KB 1OMUA 3SEKC 3SGBI 3VDUA 1ULNA 3UEYA 2UZ3A 2KMOA 2LB7A 1N13A 1NXUA 1UHAA 1AN1I 1TBQR 1Y1CA 1MJBA 2JZMA 2NU0I 3OXFA 1CHOI 2QPOA 1UUCA 3E2IA 2QQCA 2V53A 2Y0MA 4HGUA 1CT0I 2SGEI 5CCLA 2JA1A 1SGEI 4UXIA 2JYYA 1XX6A 2N17A 1IY6A 3FSYA 1U5KA 2B8TA 3QWPA 1MT1A 3FSXA 1TBNA 1TGSI 2F3CI 2ELIA 4UXHA 1X4SA 5J8FA 1OYVI 1HEVA 3RU0A 1MJ9A 3TO6A 2L8EA 2GVIA 3OL0A 3B4VC 2JW6A 2LUYA 1PTQA 3TO9A 1WTJA 1CGII 2WVJA 2GKRI 1WGTA 2OZUA 2SGFI 2RIJA 1DS3I 4AMLA 4GI3C 1DS2I 5DAEA 2B0UC 1Q9BA 2CJSC 2YUUA 3OXGA 3D00A 5HQ8A 2ROWA 1FAQA 2OU2A 5EX3A 1K7UA 2V1CA 3E59A 3QAHA 1WKXA 5FUWA 4L9MA 1CT4I 2V1CC 1UVFA 1Z2IA 5J8CA 1MJAA 1CGJI 2WCYA 1P9GA 2ERWA 2UVOA 1KBEA 2CWHA 2GIVA 4DNCA 1KMAA 1YTPA 2GKVA 2ENNA 2K9HA 1OMTA 3R5AA 1K7TA 1BMOA 2P6AC 2FNFX 2X3TA 1UVGA 1X74A 2KMQA 5FUYA 3CXLA 7WGAA 3UGDA 2X52A 1LR9A 2DB6A 2N71A 1TUSA 2XRCA 4MPIA 1BUSA 2L7XA 1LR7A 2SGDI 2SGQI 3KY9A 5EX0A 4WP4A 3TJQA 1FYBA 1SGDI 1LR8A 3TO7A 1Y8FA 4A24A 2RC4A 2NU4I 2YQPA 1RFHA 2QQDA 5E3RA 1V1IA 2WGCA 3TOAA 1VDDA 1XA6A 1K7VA 1NUBA 3R5CA 3VDPA 5JHWC 3R5BA 4JCVE 1W3SA 1HDLA 2J9RA 1OVOA 5FUXA 2DIPA 2BUSA 1CT2I 5HI7A 2DKVA 2M5XA 1HPTA 3FC3A 1SGQI 3UOEA 3UFFA 1R0RI 1PCEA 1ULKA 1Y1BA 2ODDA 5E3PA 5CCMA 2NU1I 1WGCA 2QQ0A 2N52A 3UGLA 4E1PA 2E73A 4OVOA 4FKDA 4UXJA 3UEJA 9WGAA 2ORVA 2NU2I 1TURA 1SGRI 1TOTA 2SGPI 2A20A 3HH2C 5FUVA 3VE5A 2PQ8A 2W0TA 1S20A 2KMRA 3OXLA 1V1HA 1CSOI 3MEKA 2KCXA 4B6DA 1TIHA 3UGIA 2CWFA 2JXDA 5E3QA 1W4RA 1M8CA 1R79A 3SGQI 2OD1A 1H0ZA 1TBRR 1XBTA 2ARPF 1M8BA 1PPFI 1CE3A 3OVOA 1IW4A 1PJUA 2CWGA 2J87A 1IY5A 1SGPI 1P9ZA 2LEOA 2OVOA 3PDNA 3TOBA 2E5RA 1SGYI 1SGNI 2GKTI 2ORWA 2ENZA 1YU6C 4E1RA 1KBFA 2N1AB 2VRWB 3BJIA 1PTRA 2QQEA 1FARA
chains in the Genus database with same CATH topology
3QTLD 4SGBI 2KMPA 1HJAI 1TBOA 3GOXA 2NU3I 1Z7KB 1OMUA 3SEKC 3SGBI 3VDUA 3UEYA 2UZ3A 2KMOA 1N13A 1Y1CA 2JZMA 1AN1I 1TBQR 3OXFA 2NU0I 1CHOI 2QPOA 1UUCA 3E2IA 2QQCA 2V53A 4HGUA 1CT0I 2SGEI 5CCLA 2JA1A 1SGEI 4UXIA 2JYYA 1XX6A 2N17A 1IY6A 1U5KA 2B8TA 3QWPA 1MT1A 1TBNA 1TGSI 2F3CI 2ELIA 4UXHA 1X4SA 1OYVI 3RU0A 2L8EA 2GVIA 3OL0A 3B4VC 2JW6A 2LUYA 1PTQA 1CGII 2WVJA 2GKRI 2SGFI 1DS3I 4GI3C 1DS2I 5DAEA 2B0UC 2CJSC 2YUUA 3OXGA 5HQ8A 3D00A 1FAQA 2ROWA 5EX3A 2V1CA 3E59A 5FUWA 4L9MA 1CT4I 2V1CC 1UVFA 1CGJI 2WCYA 2ERWA 1KBEA 1KMAA 1YTPA 2GKVA 2ENNA 2K9HA 1OMTA 1BMOA 2P6AC 2FNFX 1UVGA 1X74A 2KMQA 5FUYA 3CXLA 3UGDA 1LR9A 2DB6A 2N71A 1TUSA 2XRCA 1BUSA 2L7XA 1LR7A 2SGDI 2SGQI 3KY9A 5EX0A 3TJQA 1FYBA 1SGDI 1LR8A 1Y8FA 4A24A 2NU4I 2YQPA 1RFHA 2QQDA 1V1IA 1VDDA 1XA6A 1NUBA 3VDPA 5JHWC 4JCVE 1W3SA 1HDLA 2J9RA 1OVOA 5FUXA 2DIPA 2BUSA 1CT2I 5HI7A 2M5XA 1HPTA 3FC3A 1SGQI 3UFFA 1R0RI 1PCEA 2ODDA 1Y1BA 5CCMA 2NU1I 2QQ0A 3UGLA 2N52A 4E1PA 2E73A 4OVOA 4FKDA 4UXJA 3UEJA 2ORVA 2NU2I 1TURA 1SGRI 1TOTA 2SGPI 2A20A 3HH2C 5FUVA 3VE5A 2W0TA 2KMRA 3OXLA 1V1HA 1CSOI 3MEKA 2KCXA 4B6DA 1TIHA 3UGIA 2JXDA 1H0ZA 3SGQI 1W4RA 1M8CA 1R79A 2OD1A 1TBRR 1XBTA 2ARPF 1M8BA 1PPFI 1CE3A 3OVOA 1IW4A 1PJUA 2J87A 1IY5A 1SGPI 2LEOA 2OVOA 3PDNA 2E5RA 1SGYI 1SGNI 2GKTI 2ORWA 2ENZA 1YU6C 4E1RA 1KBFA 2N1AB 2VRWB 3BJIA 1PTRA 2QQEA 1FARA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QTL D;  4SGB I;  2KMP A;  1HJA I;  2NU3 I;  1Z7K B;  1OMU A;  3SEK C;  3SGB I;  2KMO A;  1N13 A;  1Y1C A;  2JZM A;  1AN1 I;  1TBQ R;  2NU0 I;  1CHO I;  1UUC A;  2QQC A;  2V53 A;  4HGU A;  1CT0 I;  2SGE I;  1SGE I;  2JYY A;  2N17 A;  1IY6 A;  1MT1 A;  1TGS I;  2F3C I;  1OYV I;  3B4V C;  1CGI I;  2GKR I;  2SGF I;  1DS3 I;  1DS2 I;  5DAE A;  2B0U C;  1CT4 I;  1UVF A;  1CGJ I;  2WCY A;  2ERW A;  1KMA A;  1YTP A;  2GKV A;  1OMT A;  1BMO A;  2P6A C;  1UVG A;  2KMQ A;  1LR9 A;  2N71 A;  1TUS A;  2XRC A;  1BUS A;  1LR7 A;  2SGD I;  2SGQ I;  3TJQ A;  1FYB A;  1SGD I;  1LR8 A;  2NU4 I;  2QQD A;  1NUB A;  5JHW C;  1HDL A;  1OVO A;  2BUS A;  1CT2 I;  2M5X A;  1HPT A;  1SGQ I;  1R0R I;  1PCE A;  1Y1B A;  2NU1 I;  2N52 A;  4OVO A;  2NU2 I;  1TUR A;  1SGR I;  2SGP I;  3HH2 C;  2KMR A;  1CSO I;  2KCX A;  1TIH A;  2JXD A;  1H0Z A;  3SGQ I;  1M8C A;  1TBR R;  2ARP F;  1CE3 A;  1M8B A;  1PPF I;  3OVO A;  1IW4 A;  1PJU A;  1IY5 A;  1SGP I;  2LEO A;  2OVO A;  1SGY I;  1SGN I;  2GKT I;  1YU6 C;  4GI3 C; 
#chains in the Genus database with same CATH topology
 1FY7 A;  3QTL D;  4SGB I;  3R5D A;  2KMP A;  1HJA I;  1TBO A;  3GOX A;  2NU3 I;  1ULM A;  1Z7K B;  1OMU A;  3SEK C;  3SGB I;  3VDU A;  1ULN A;  3UEY A;  2UZ3 A;  2KMO A;  2LB7 A;  1N13 A;  1NXU A;  1UHA A;  1AN1 I;  1TBQ R;  1Y1C A;  1MJB A;  2JZM A;  2NU0 I;  3OXF A;  1CHO I;  2QPO A;  1UUC A;  3E2I A;  2QQC A;  2V53 A;  2Y0M A;  4HGU A;  1CT0 I;  2SGE I;  5CCL A;  2JA1 A;  1SGE I;  4UXI A;  2JYY A;  1XX6 A;  2N17 A;  1IY6 A;  3FSY A;  1U5K A;  2B8T A;  3QWP A;  1MT1 A;  3FSX A;  1TBN A;  1TGS I;  2F3C I;  2ELI A;  4UXH A;  1X4S A;  5J8F A;  1OYV I;  1HEV A;  3RU0 A;  1MJ9 A;  3TO6 A;  2L8E A;  2GVI A;  3OL0 A;  3B4V C;  2JW6 A;  2LUY A;  1PTQ A;  3TO9 A;  1WTJ A;  1CGI I;  2WVJ A;  2GKR I;  1WGT A;  2OZU A;  2SGF I;  2RIJ A;  1DS3 I;  4AML A;  4GI3 C;  1DS2 I;  5DAE A;  2B0U C;  1Q9B A;  2CJS C;  2YUU A;  3OXG A;  3D00 A;  5HQ8 A;  2ROW A;  1FAQ A;  2OU2 A;  5EX3 A;  1K7U A;  2V1C A;  3E59 A;  3QAH A;  1WKX A;  5FUW A;  4L9M A;  1CT4 I;  2V1C C;  1UVF A;  1Z2I A;  5J8C A;  1MJA A;  1CGJ I;  2WCY A;  1P9G A;  2ERW A;  2UVO A;  1KBE A;  2CWH A;  2GIV A;  4DNC A;  1KMA A;  1YTP A;  2GKV A;  2ENN A;  2K9H A;  1OMT A;  3R5A A;  1K7T A;  1BMO A;  2P6A C;  2FNF X;  2X3T A;  1UVG A;  1X74 A;  2KMQ A;  5FUY A;  3CXL A;  7WGA A;  3UGD A;  2X52 A;  1LR9 A;  2DB6 A;  2N71 A;  1TUS A;  2XRC A;  4MPI A;  1BUS A;  2L7X A;  1LR7 A;  2SGD I;  2SGQ I;  3KY9 A;  5EX0 A;  4WP4 A;  3TJQ A;  1FYB A;  1SGD I;  1LR8 A;  3TO7 A;  1Y8F A;  4A24 A;  2RC4 A;  2NU4 I;  2YQP A;  1RFH A;  2QQD A;  5E3R A;  1V1I A;  2WGC A;  3TOA A;  1VDD A;  1XA6 A;  1K7V A;  1NUB A;  3R5C A;  3VDP A;  5JHW C;  3R5B A;  4JCV E;  1W3S A;  1HDL A;  2J9R A;  1OVO A;  5FUX A;  2DIP A;  2BUS A;  1CT2 I;  5HI7 A;  2DKV A;  2M5X A;  1HPT A;  3FC3 A;  1SGQ I;  3UOE A;  3UFF A;  1R0R I;  1PCE A;  1ULK A;  1Y1B A;  2ODD A;  5E3P A;  5CCM A;  2NU1 I;  1WGC A;  2QQ0 A;  2N52 A;  3UGL A;  4E1P A;  2E73 A;  4OVO A;  4FKD A;  4UXJ A;  3UEJ A;  9WGA A;  2ORV A;  2NU2 I;  1TUR A;  1SGR I;  1TOT A;  2SGP I;  2A20 A;  3HH2 C;  5FUV A;  3VE5 A;  2PQ8 A;  2W0T A;  1S20 A;  2KMR A;  3OXL A;  1V1H A;  1CSO I;  3MEK A;  2KCX A;  4B6D A;  1TIH A;  3UGI A;  2CWF A;  2JXD A;  5E3Q A;  1W4R A;  1M8C A;  1R79 A;  3SGQ I;  2OD1 A;  1H0Z A;  1TBR R;  1XBT A;  2ARP F;  1M8B A;  1PPF I;  1CE3 A;  3OVO A;  1IW4 A;  1PJU A;  2CWG A;  2J87 A;  1IY5 A;  1SGP I;  1P9Z A;  2LEO A;  2OVO A;  3PDN A;  3TOB A;  2E5R A;  1SGY I;  1SGN I;  2GKT I;  2ORW A;  2ENZ A;  1YU6 C;  4E1R A;  1KBF A;  2N1A B;  2VRW B;  3BJI A;  1PTR A;  2QQE A;  1FAR A; 
#chains in the Genus database with same CATH homology
 3QTL D;  4SGB I;  2KMP A;  1HJA I;  1TBO A;  3GOX A;  2NU3 I;  1Z7K B;  1OMU A;  3SEK C;  3SGB I;  3VDU A;  3UEY A;  2UZ3 A;  2KMO A;  1N13 A;  1Y1C A;  2JZM A;  1AN1 I;  1TBQ R;  3OXF A;  2NU0 I;  1CHO I;  2QPO A;  1UUC A;  3E2I A;  2QQC A;  2V53 A;  4HGU A;  1CT0 I;  2SGE I;  5CCL A;  2JA1 A;  1SGE I;  4UXI A;  2JYY A;  1XX6 A;  2N17 A;  1IY6 A;  1U5K A;  2B8T A;  3QWP A;  1MT1 A;  1TBN A;  1TGS I;  2F3C I;  2ELI A;  4UXH A;  1X4S A;  1OYV I;  3RU0 A;  2L8E A;  2GVI A;  3OL0 A;  3B4V C;  2JW6 A;  2LUY A;  1PTQ A;  1CGI I;  2WVJ A;  2GKR I;  2SGF I;  1DS3 I;  4GI3 C;  1DS2 I;  5DAE A;  2B0U C;  2CJS C;  2YUU A;  3OXG A;  5HQ8 A;  3D00 A;  1FAQ A;  2ROW A;  5EX3 A;  2V1C A;  3E59 A;  5FUW A;  4L9M A;  1CT4 I;  2V1C C;  1UVF A;  1CGJ I;  2WCY A;  2ERW A;  1KBE A;  1KMA A;  1YTP A;  2GKV A;  2ENN A;  2K9H A;  1OMT A;  1BMO A;  2P6A C;  2FNF X;  1UVG A;  1X74 A;  2KMQ A;  5FUY A;  3CXL A;  3UGD A;  1LR9 A;  2DB6 A;  2N71 A;  1TUS A;  2XRC A;  1BUS A;  2L7X A;  1LR7 A;  2SGD I;  2SGQ I;  3KY9 A;  5EX0 A;  3TJQ A;  1FYB A;  1SGD I;  1LR8 A;  1Y8F A;  4A24 A;  2NU4 I;  2YQP A;  1RFH A;  2QQD A;  1V1I A;  1VDD A;  1XA6 A;  1NUB A;  3VDP A;  5JHW C;  4JCV E;  1W3S A;  1HDL A;  2J9R A;  1OVO A;  5FUX A;  2DIP A;  2BUS A;  1CT2 I;  5HI7 A;  2M5X A;  1HPT A;  3FC3 A;  1SGQ I;  3UFF A;  1R0R I;  1PCE A;  2ODD A;  1Y1B A;  5CCM A;  2NU1 I;  2QQ0 A;  3UGL A;  2N52 A;  4E1P A;  2E73 A;  4OVO A;  4FKD A;  4UXJ A;  3UEJ A;  2ORV A;  2NU2 I;  1TUR A;  1SGR I;  1TOT A;  2SGP I;  2A20 A;  3HH2 C;  5FUV A;  3VE5 A;  2W0T A;  2KMR A;  3OXL A;  1V1H A;  1CSO I;  3MEK A;  2KCX A;  4B6D A;  1TIH A;  3UGI A;  2JXD A;  1H0Z A;  3SGQ I;  1W4R A;  1M8C A;  1R79 A;  2OD1 A;  1TBR R;  1XBT A;  2ARP F;  1M8B A;  1PPF I;  1CE3 A;  3OVO A;  1IW4 A;  1PJU A;  2J87 A;  1IY5 A;  1SGP I;  2LEO A;  2OVO A;  3PDN A;  2E5R A;  1SGY I;  1SGN I;  2GKT I;  2ORW A;  2ENZ A;  1YU6 C;  4E1R A;  1KBF A;  2N1A B;  2VRW B;  3BJI A;  1PTR A;  2QQE A;  1FAR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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