2ROWA

The c1 domain of rock ii
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
84
structure length
84
Chain Sequence
ESKKEPEFPVEPVGEKSNYICHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The C1 domain of ROCK II
rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords Rho-associated protein kinase 2
total genus 10
structure length 84
sequence length 84
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2008-04-25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.20 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2rowA01
1FAQA 3UGLA 2ROWA 4UXHA 1R79A 1PTRA 1XX6A 2WVJA 2E73A 2QQ0A 2QPOA 1W4RA 2UZ3A 2FNFX 2ELIA 4FKDA 1FARA 2GVIA 1PTQA 1Y8FA 2VRWB 2ORVA 2ENZA 1TBOA 3UFFA 1XA6A 1TBNA 3CXLA 5FUXA 2J9RA 3UGDA 4B6DA 1XBTA 5FUYA 3KY9A 2B8TA 1KBEA 2ORWA 2J87A 5FUWA 4UXJA 5FUVA 2QQEA 2YUUA 2ENNA 2JA1A 4L9MA 3UEJA 3UEYA 3BJIA 1RFHA 2DB6A 3E2IA 3UGIA 4UXIA 1KBFA
chains in the Genus database with same CATH superfamily
1FAQA 2ROWA 1BUSA 2WVJA 3HH2C 9WGAA 2NU3I 1HPTA 2KMPA 1Z2IA 2KMRA 2ELIA 2N17A 1FARA 2JXDA 3OVOA 1PTQA 5DAEA 5E3PA 2VRWB 2SGQI 2CJSC 5E3RA 1X74A 2GKVA 1SGPI 1TBNA 3CXLA 3QTLD 4E1PA 5FUXA 5CCLA 1FYBA 1SGYI 1TGSI 1TBRR 2SGPI 3QAHA 1WKXA 1SGQI 4AMLA 2GKTI 2ORWA 5HI7A 1HJAI 1UVFA 1V1HA 1V1IA 3TOAA 2QQCA 1Y1CA 5FUWA 3RU0A 1P9GA 2QQEA 2KCXA 2N1AB 1M8CA 2SGEI 1CSOI 3BJIA 1UUCA 3OXGA 2Y0MA 3VE5A 1Z7KB 3TO7A 2YQPA 2ODDA 5EX3A 3UOEA 1K7UA 3SGQI 2QQ0A 2LB7A 1W4RA 3VDUA 3MEKA 2SGFI 2UZ3A 4FKDA 1SGDI 1N13A 1K7VA 1MJBA 2ENZA 1TBOA 3UFFA 1XA6A 2JYYA 1KBFA 2V1CC 2X52A 3GOXA 4UXIA 1CT4I 1TUSA 1UHAA 1LR7A 2NU2I 1LR8A 1SGNI 2J9RA 1TBQR 3UGDA 1TURA 2OU2A 1NUBA 1XBTA 3OXLA 1PPFI 1TOTA 1HDLA 3R5DA 2K9HA 1KBEA 1R0RI 2OVOA 1MJ9A 2J87A 3FSXA 1BMOA 1P9ZA 3SEKC 1CT2I 1X4SA 3TO9A 3FC3A 5FUVA 1CHOI 2GKRI 2CWFA 2CWHA 2W0TA 2YUUA 1WGCA 2E5RA 2DB6A 1NXUA 1YTPA 2ARPF 1TIHA 1IY6A 1LR9A 2N71A 3FSYA 1WGTA 5J8CA 1K7TA 2OD1A 7WGAA 5JHWC 2NU4I 1DS2I 1DS3I 1PTRA 1XX6A 1FY7A 1PJUA 3B4VC 2OZUA 2ERWA 1YU6C 3OXFA 2GVIA 1CGII 1IY5A 1MJAA 1ULKA 2DIPA 1CGJI 1S20A 2ORVA 2XRCA 5EX0A 3VDPA 3TO6A 2GIVA 1ULNA 2PQ8A 3R5AA 2JZMA 4B6DA 5HQ8A 5FUYA 3KY9A 3TJQA 4A24A 2KMOA 1OYVI 1PCEA 1VDDA 4SGBI 5E3QA 2P6AC 1U5KA 3PDNA 1UVGA 2B0UC 4UXJA 2ENNA 4L9MA 2QQDA 1RFHA 1OMUA 2WGCA 2NU0I 2LUYA 2WCYA 3R5CA 1IW4A 1OMTA 1H0ZA 2X3TA 2BUSA 3E59A 5J8FA 1OVOA 2L8EA 2UVOA 1M8BA 3UGLA 4UXHA 1HEVA 1R79A 4E1RA 2JW6A 2E73A 2NU1I 2QPOA 3D00A 1SGEI 2FNFX 1AN1I 2CWGA 1Q9BA 2N52A 1Y8FA 2LEOA 1KMAA 4JCVE 4DNCA 1W3SA 2SGDI 5CCMA 3OL0A 4GI3C 2RIJA 2B8TA 3SGBI 2KMQA 1Y1BA 4OVOA 2M5XA 3TOBA 3QWPA 1CE3A 1WTJA 4MPIA 1SGRI 3UEYA 2JA1A 3UEJA 3R5BA 2A20A 1CT0I 2F3CI 2L7XA 4WP4A 3E2IA 2RC4A 1MT1A 3UGIA 2DKVA 2V1CA 1ULMA 4HGUA 2V53A
chains in the Genus database with same CATH topology
1FAQA 2ROWA 1BUSA 2WVJA 3HH2C 2NU3I 1HPTA 2KMPA 2KMRA 2ELIA 2N17A 1FARA 2JXDA 3OVOA 1PTQA 5DAEA 2VRWB 2SGQI 2CJSC 1X74A 2GKVA 1SGPI 1TBNA 3CXLA 3QTLD 4E1PA 5FUXA 5CCLA 1FYBA 1SGYI 1TGSI 1TBRR 2SGPI 1SGQI 2GKTI 2ORWA 5HI7A 1HJAI 1UVFA 1V1HA 1V1IA 2QQCA 1Y1CA 5FUWA 3RU0A 2QQEA 2KCXA 2N1AB 1M8CA 2SGEI 1CSOI 3BJIA 1UUCA 3OXGA 3VE5A 1Z7KB 2YQPA 2ODDA 5EX3A 3SGQI 2QQ0A 3VDUA 1W4RA 3MEKA 2SGFI 2UZ3A 4FKDA 1SGDI 1N13A 2ENZA 1TBOA 3UFFA 1XA6A 2JYYA 1KBFA 2V1CC 3GOXA 4UXIA 1CT4I 1TUSA 5HQ8A 1LR7A 2NU2I 1LR8A 1SGNI 2J9RA 1TBQR 3UGDA 1TURA 1NUBA 1XBTA 3OXLA 1PPFI 1TOTA 1HDLA 2K9HA 1KBEA 1R0RI 2OVOA 2J87A 1BMOA 3SEKC 1CT2I 1X4SA 3FC3A 5FUVA 1CHOI 2GKRI 2W0TA 2YUUA 2E5RA 2DB6A 1YTPA 2ARPF 1TIHA 1IY6A 1LR9A 2N71A 5JHWC 2OD1A 2NU4I 1DS2I 1DS3I 1PTRA 1XX6A 1PJUA 3B4VC 2ERWA 1YU6C 3OXFA 2GVIA 1CGII 1IY5A 2DIPA 2ORVA 1CGJI 2XRCA 3VDPA 5EX0A 4B6DA 2JZMA 5FUYA 3KY9A 3TJQA 4A24A 2KMOA 1OYVI 1PCEA 1VDDA 4SGBI 2P6AC 1U5KA 3PDNA 1UVGA 2B0UC 4UXJA 2ENNA 4L9MA 2QQDA 1RFHA 1OMUA 2NU0I 2LUYA 2WCYA 1IW4A 1OMTA 1H0ZA 2BUSA 3E59A 1OVOA 2L8EA 1M8BA 3UGLA 4UXHA 1R79A 4E1RA 2JW6A 2E73A 2NU1I 2QPOA 3D00A 1SGEI 2FNFX 1AN1I 2N52A 1Y8FA 2LEOA 1KMAA 4JCVE 1W3SA 2SGDI 5CCMA 3OL0A 4GI3C 2B8TA 3SGBI 2KMQA 1Y1BA 4OVOA 2M5XA 3QWPA 1CE3A 1SGRI 3UEYA 2JA1A 3UEJA 2A20A 1CT0I 2F3CI 2L7XA 3E2IA 1MT1A 3UGIA 2V1CA 4HGUA 2V53A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FAQ A;  3UGL A;  2ROW A;  4UXH A;  1R79 A;  1PTR A;  1XX6 A;  2WVJ A;  2E73 A;  2QQ0 A;  2QPO A;  1W4R A;  2UZ3 A;  2FNF X;  2ELI A;  4FKD A;  1FAR A;  2GVI A;  1PTQ A;  1Y8F A;  2VRW B;  2ORV A;  2ENZ A;  1TBO A;  3UFF A;  1XA6 A;  1TBN A;  3CXL A;  5FUX A;  2J9R A;  3UGD A;  4B6D A;  1XBT A;  5FUY A;  3KY9 A;  2B8T A;  1KBE A;  2ORW A;  2J87 A;  5FUW A;  4UXJ A;  5FUV A;  2QQE A;  2YUU A;  2ENN A;  2JA1 A;  4L9M A;  3UEJ A;  3UEY A;  3BJI A;  1RFH A;  2DB6 A;  3E2I A;  3UGI A;  4UXI A;  1KBF A; 
#chains in the Genus database with same CATH topology
 1FAQ A;  2ROW A;  1BUS A;  2WVJ A;  3HH2 C;  9WGA A;  2NU3 I;  1HPT A;  2KMP A;  1Z2I A;  2KMR A;  2ELI A;  2N17 A;  1FAR A;  2JXD A;  3OVO A;  1PTQ A;  5DAE A;  5E3P A;  2VRW B;  2SGQ I;  2CJS C;  5E3R A;  1X74 A;  2GKV A;  1SGP I;  1TBN A;  3CXL A;  3QTL D;  4E1P A;  5FUX A;  5CCL A;  1FYB A;  1SGY I;  1TGS I;  1TBR R;  2SGP I;  3QAH A;  1WKX A;  1SGQ I;  4AML A;  2GKT I;  2ORW A;  5HI7 A;  1HJA I;  1UVF A;  1V1H A;  1V1I A;  3TOA A;  2QQC A;  1Y1C A;  5FUW A;  3RU0 A;  1P9G A;  2QQE A;  2KCX A;  2N1A B;  1M8C A;  2SGE I;  1CSO I;  3BJI A;  1UUC A;  3OXG A;  2Y0M A;  3VE5 A;  1Z7K B;  3TO7 A;  2YQP A;  2ODD A;  5EX3 A;  3UOE A;  1K7U A;  3SGQ I;  2QQ0 A;  2LB7 A;  1W4R A;  3VDU A;  3MEK A;  2SGF I;  2UZ3 A;  4FKD A;  1SGD I;  1N13 A;  1K7V A;  1MJB A;  2ENZ A;  1TBO A;  3UFF A;  1XA6 A;  2JYY A;  1KBF A;  2V1C C;  2X52 A;  3GOX A;  4UXI A;  1CT4 I;  1TUS A;  1UHA A;  1LR7 A;  2NU2 I;  1LR8 A;  1SGN I;  2J9R A;  1TBQ R;  3UGD A;  1TUR A;  2OU2 A;  1NUB A;  1XBT A;  3OXL A;  1PPF I;  1TOT A;  1HDL A;  3R5D A;  2K9H A;  1KBE A;  1R0R I;  2OVO A;  1MJ9 A;  2J87 A;  3FSX A;  1BMO A;  1P9Z A;  3SEK C;  1CT2 I;  1X4S A;  3TO9 A;  3FC3 A;  5FUV A;  1CHO I;  2GKR I;  2CWF A;  2CWH A;  2W0T A;  2YUU A;  1WGC A;  2E5R A;  2DB6 A;  1NXU A;  1YTP A;  2ARP F;  1TIH A;  1IY6 A;  1LR9 A;  2N71 A;  3FSY A;  1WGT A;  5J8C A;  1K7T A;  2OD1 A;  7WGA A;  5JHW C;  2NU4 I;  1DS2 I;  1DS3 I;  1PTR A;  1XX6 A;  1FY7 A;  1PJU A;  3B4V C;  2OZU A;  2ERW A;  1YU6 C;  3OXF A;  2GVI A;  1CGI I;  1IY5 A;  1MJA A;  1ULK A;  2DIP A;  1CGJ I;  1S20 A;  2ORV A;  2XRC A;  5EX0 A;  3VDP A;  3TO6 A;  2GIV A;  1ULN A;  2PQ8 A;  3R5A A;  2JZM A;  4B6D A;  5HQ8 A;  5FUY A;  3KY9 A;  3TJQ A;  4A24 A;  2KMO A;  1OYV I;  1PCE A;  1VDD A;  4SGB I;  5E3Q A;  2P6A C;  1U5K A;  3PDN A;  1UVG A;  2B0U C;  4UXJ A;  2ENN A;  4L9M A;  2QQD A;  1RFH A;  1OMU A;  2WGC A;  2NU0 I;  2LUY A;  2WCY A;  3R5C A;  1IW4 A;  1OMT A;  1H0Z A;  2X3T A;  2BUS A;  3E59 A;  5J8F A;  1OVO A;  2L8E A;  2UVO A;  1M8B A;  3UGL A;  4UXH A;  1HEV A;  1R79 A;  4E1R A;  2JW6 A;  2E73 A;  2NU1 I;  2QPO A;  3D00 A;  1SGE I;  2FNF X;  1AN1 I;  2CWG A;  1Q9B A;  2N52 A;  1Y8F A;  2LEO A;  1KMA A;  4JCV E;  4DNC A;  1W3S A;  2SGD I;  5CCM A;  3OL0 A;  4GI3 C;  2RIJ A;  2B8T A;  3SGB I;  2KMQ A;  1Y1B A;  4OVO A;  2M5X A;  3TOB A;  3QWP A;  1CE3 A;  1WTJ A;  4MPI A;  1SGR I;  3UEY A;  2JA1 A;  3UEJ A;  3R5B A;  2A20 A;  1CT0 I;  2F3C I;  2L7X A;  4WP4 A;  3E2I A;  2RC4 A;  1MT1 A;  3UGI A;  2DKV A;  2V1C A;  1ULM A;  4HGU A;  2V53 A; 
#chains in the Genus database with same CATH homology
 1FAQ A;  2ROW A;  1BUS A;  2WVJ A;  3HH2 C;  2NU3 I;  1HPT A;  2KMP A;  2KMR A;  2ELI A;  2N17 A;  1FAR A;  2JXD A;  3OVO A;  1PTQ A;  5DAE A;  2VRW B;  2SGQ I;  2CJS C;  1X74 A;  2GKV A;  1SGP I;  1TBN A;  3CXL A;  3QTL D;  4E1P A;  5FUX A;  5CCL A;  1FYB A;  1SGY I;  1TGS I;  1TBR R;  2SGP I;  1SGQ I;  2GKT I;  2ORW A;  5HI7 A;  1HJA I;  1UVF A;  1V1H A;  1V1I A;  2QQC A;  1Y1C A;  5FUW A;  3RU0 A;  2QQE A;  2KCX A;  2N1A B;  1M8C A;  2SGE I;  1CSO I;  3BJI A;  1UUC A;  3OXG A;  3VE5 A;  1Z7K B;  2YQP A;  2ODD A;  5EX3 A;  3SGQ I;  2QQ0 A;  3VDU A;  1W4R A;  3MEK A;  2SGF I;  2UZ3 A;  4FKD A;  1SGD I;  1N13 A;  2ENZ A;  1TBO A;  3UFF A;  1XA6 A;  2JYY A;  1KBF A;  2V1C C;  3GOX A;  4UXI A;  1CT4 I;  1TUS A;  5HQ8 A;  1LR7 A;  2NU2 I;  1LR8 A;  1SGN I;  2J9R A;  1TBQ R;  3UGD A;  1TUR A;  1NUB A;  1XBT A;  3OXL A;  1PPF I;  1TOT A;  1HDL A;  2K9H A;  1KBE A;  1R0R I;  2OVO A;  2J87 A;  1BMO A;  3SEK C;  1CT2 I;  1X4S A;  3FC3 A;  5FUV A;  1CHO I;  2GKR I;  2W0T A;  2YUU A;  2E5R A;  2DB6 A;  1YTP A;  2ARP F;  1TIH A;  1IY6 A;  1LR9 A;  2N71 A;  5JHW C;  2OD1 A;  2NU4 I;  1DS2 I;  1DS3 I;  1PTR A;  1XX6 A;  1PJU A;  3B4V C;  2ERW A;  1YU6 C;  3OXF A;  2GVI A;  1CGI I;  1IY5 A;  2DIP A;  2ORV A;  1CGJ I;  2XRC A;  3VDP A;  5EX0 A;  4B6D A;  2JZM A;  5FUY A;  3KY9 A;  3TJQ A;  4A24 A;  2KMO A;  1OYV I;  1PCE A;  1VDD A;  4SGB I;  2P6A C;  1U5K A;  3PDN A;  1UVG A;  2B0U C;  4UXJ A;  2ENN A;  4L9M A;  2QQD A;  1RFH A;  1OMU A;  2NU0 I;  2LUY A;  2WCY A;  1IW4 A;  1OMT A;  1H0Z A;  2BUS A;  3E59 A;  1OVO A;  2L8E A;  1M8B A;  3UGL A;  4UXH A;  1R79 A;  4E1R A;  2JW6 A;  2E73 A;  2NU1 I;  2QPO A;  3D00 A;  1SGE I;  2FNF X;  1AN1 I;  2N52 A;  1Y8F A;  2LEO A;  1KMA A;  4JCV E;  1W3S A;  2SGD I;  5CCM A;  3OL0 A;  4GI3 C;  2B8T A;  3SGB I;  2KMQ A;  1Y1B A;  4OVO A;  2M5X A;  3QWP A;  1CE3 A;  1SGR I;  3UEY A;  2JA1 A;  3UEJ A;  2A20 A;  1CT0 I;  2F3C I;  2L7X A;  3E2I A;  1MT1 A;  3UGI A;  2V1C A;  4HGU A;  2V53 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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