2SGPI

Pro 18 variant of turkey ovomucoid inhibitor third domain complexed with streptomyces griseus proteinase b at ph 6.5
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
51
structure length
51
Chain Sequence
VDCSEYPKPACTPEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I
pubmed doi rcsb
molecule tags Hydrolase/inhibitor
source organism Meleagris gallopavo
molecule keywords PROTEINASE B
total genus 11
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 1999-03-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2sgpI00
1DS3I 2M5XA 4HGUA 1KMAA 3TJQA 1OYVI 1M8BA 1SGYI 1TUSA 2LEOA 3B4VC 2N17A 2NU1I 2SGQI 4GI3C 2GKVA 2NU3I 3SGBI 1YU6C 1UVGA 1Y1BA 1CSOI 1Z7KB 2V53A 2QQCA 1PCEA 1NUBA 1DS2I 1OMTA 1UVFA 2KMPA 1TBQR 1SGPI 1MT1A 1PPFI 2XRCA 1SGNI 2GKTI 2KCXA 1OMUA 1IY6A 1SGDI 1CT0I 2SGFI 3QTLD 1HPTA 1R0RI 1LR8A 2ARPF 2SGEI 1SGQI 1TBRR 2NU2I 5DAEA 1CE3A 1IW4A 1HJAI 1CHOI 2BUSA 1BUSA 1HDLA 1CGII 1Y1CA 3SGQI 2OVOA 2JZMA 2JXDA 2KMRA 2F3CI 2N71A 1YTPA 1AN1I 1LR7A 2WCYA 1FYBA 2P6AC 2KMOA 2N52A 1IY5A 2KMQA 1UUCA 2NU4I 4OVOA 1CT4I 1TURA 1BMOA 1SGEI 1M8CA 2GKRI 2SGPI 1N13A 1CGJI 2B0UC 2QQDA 3OVOA 1H0ZA 1TGSI 4SGBI 2NU0I 1LR9A 2ERWA 1OVOA 1TIHA 2JYYA 2SGDI 3HH2C 5JHWC 1CT2I 3SEKC 1PJUA 1SGRI
chains in the Genus database with same CATH superfamily
1S20A 1TBOA 3UGIA 1DS3I 1VDDA 2M5XA 1RFHA 4HGUA 1KMAA 3TJQA 2X52A 1OYVI 4UXJA 5E3PA 5J8CA 2ODDA 4UXHA 1NXUA 9WGAA 1M8BA 2UVOA 3TOBA 3VE5A 1SGYI 1PTRA 2E5RA 4E1RA 4B6DA 1TUSA 2L8EA 2LEOA 2DB6A 3B4VC 2N17A 4FKDA 1TOTA 1P9GA 2NU1I 1MJ9A 2SGQI 3QWPA 4GI3C 5E3RA 5CCLA 2GKVA 2ENNA 3OXGA 5EX3A 2NU3I 2YUUA 3SGBI 1YU6C 1Q9BA 3OXLA 3UEYA 1UVGA 3E2IA 2V1CA 1XBTA 1CSOI 1Y1BA 2JW6A 2ROWA 1Z7KB 7WGAA 3UEJA 2V53A 1K7VA 2QQ0A 2QQCA 2RIJA 2WVJA 4E1PA 2QQEA 1PCEA 1NUBA 2A20A 1DS2I 2FNFX 4WP4A 2CWGA 1OMTA 1U5KA 1UVFA 2N1AB 2KMPA 1TBQR 1X4SA 2L7XA 3PDNA 1SGPI 5HI7A 1MT1A 1XX6A 1PPFI 2XRCA 1KBFA 1SGNI 2OZUA 3R5AA 3OXFA 2CWHA 3FSYA 3FC3A 2OU2A 2ENZA 1XA6A 2GKTI 1PTQA 2KCXA 3R5DA 1WTJA 5FUYA 3OL0A 1OMUA 2DKVA 1IY6A 1SGDI 1K7TA 1WKXA 3CXLA 1CT0I 2LUYA 2SGFI 3QTLD 1W3SA 1V1IA 1HPTA 1R0RI 2QPOA 1MJAA 1LR8A 2ARPF 2SGEI 3UFFA 1SGQI 1TBRR 1UHAA 1ULMA 3RU0A 4DNCA 2NU2I 2UZ3A 2PQ8A 2VRWB 5DAEA 1CE3A 2X3TA 1HJAI 5FUXA 1IW4A 1CHOI 1FY7A 3FSXA 2BUSA 1BUSA 3R5BA 1HDLA 1CGII 3GOXA 1FAQA 3E59A 1Y1CA 3SGQI 1WGCA 2ORVA 2OVOA 1R79A 2JZMA 1ULNA 5EX0A 3BJIA 2JXDA 3TOAA 2KMRA 4A24A 2WGCA 1FYBA 2E73A 2ORWA 3TO9A 2F3CI 2YQPA 2N71A 1YTPA 1AN1I 1LR7A 1X74A 2J87A 4JCVE 3MEKA 2K9HA 2WCYA 2LB7A 5FUVA 2J9RA 3UOEA 3TO6A 3UGDA 5CCMA 1P9ZA 4UXIA 2CWFA 1W4RA 2P6AC 5E3QA 2KMOA 2N52A 1IY5A 2KMQA 1UUCA 2NU4I 4OVOA 1CT4I 1TURA 3R5CA 3UGLA 2OD1A 1BMOA 2GVIA 1Z2IA 2V1CC 2RC4A 3VDPA 1SGEI 1M8CA 2GKRI 3QAHA 2SGPI 4AMLA 3TO7A 2CJSC 1HEVA 3KY9A 2B8TA 5HQ8A 5J8FA 1FARA 1TBNA 1N13A 2GIVA 1CGJI 5FUWA 2B0UC 3VDUA 2DIPA 1KBEA 2QQDA 3D00A 3OVOA 1H0ZA 1Y8FA 1TGSI 2W0TA 4SGBI 1V1HA 2NU0I 1ULKA 4MPIA 1LR9A 2ERWA 1OVOA 1K7UA 2Y0MA 1TIHA 2JA1A 2JYYA 2SGDI 3HH2C 4L9MA 5JHWC 1CT2I 2ELIA 1MJBA 3SEKC 1PJUA 1WGTA 1SGRI
chains in the Genus database with same CATH topology
1TBOA 3UGIA 1DS3I 1VDDA 2M5XA 1RFHA 4HGUA 1KMAA 3TJQA 1OYVI 4UXJA 2ODDA 4UXHA 1M8BA 3VE5A 1SGYI 1PTRA 2E5RA 4E1RA 4B6DA 1TUSA 2L8EA 2LEOA 2DB6A 3B4VC 2N17A 4FKDA 1TOTA 2NU1I 2SGQI 3QWPA 5CCLA 4GI3C 2GKVA 2ENNA 3OXGA 5EX3A 2NU3I 2YUUA 3SGBI 1YU6C 3UEYA 3OXLA 1UVGA 3E2IA 2V1CA 1XBTA 1CSOI 1Y1BA 2JW6A 2ROWA 1Z7KB 3UEJA 2V53A 2QQ0A 2QQCA 2WVJA 4E1PA 2QQEA 1PCEA 1NUBA 2A20A 1DS2I 2FNFX 2N1AB 1OMTA 1U5KA 1UVFA 2KMPA 1TBQR 1X4SA 2L7XA 3PDNA 1SGPI 5HI7A 1MT1A 1XX6A 1PPFI 2XRCA 1KBFA 1SGNI 3OXFA 3FC3A 2ENZA 1XA6A 2GKTI 1PTQA 2KCXA 5FUYA 3OL0A 1OMUA 1IY6A 1SGDI 3CXLA 1CT0I 2LUYA 2SGFI 3QTLD 1W3SA 1V1IA 1HPTA 1R0RI 2QPOA 1LR8A 2ARPF 2SGEI 3UFFA 1SGQI 1TBRR 3RU0A 2NU2I 2UZ3A 2VRWB 5DAEA 1CE3A 1IW4A 1HJAI 5FUXA 1CHOI 2BUSA 1BUSA 1HDLA 1CGII 3GOXA 1FAQA 3E59A 1Y1CA 3SGQI 2ORVA 2OVOA 1R79A 2JZMA 5EX0A 4A24A 3BJIA 2JXDA 2KMRA 2ORWA 2F3CI 2YQPA 2N71A 1YTPA 1AN1I 1LR7A 1X74A 2J87A 4JCVE 3MEKA 2K9HA 2WCYA 5FUVA 2J9RA 5CCMA 3UGDA 1FYBA 4UXIA 2P6AC 1W4RA 2KMOA 2N52A 1IY5A 2KMQA 1UUCA 2NU4I 4OVOA 1CT4I 1TURA 3UGLA 2OD1A 1BMOA 2GVIA 2V1CC 3VDPA 1SGEI 1M8CA 2GKRI 2SGPI 2CJSC 3KY9A 2B8TA 5HQ8A 1FARA 1TBNA 1N13A 5FUWA 1CGJI 3VDUA 2B0UC 2DIPA 1KBEA 2QQDA 3D00A 3OVOA 1H0ZA 1Y8FA 1TGSI 2W0TA 4SGBI 1V1HA 2NU0I 1LR9A 2ERWA 1OVOA 1TIHA 2JA1A 2JYYA 2SGDI 3HH2C 4L9MA 5JHWC 1CT2I 2ELIA 3SEKC 1PJUA 2E73A 1SGRI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DS3 I;  2M5X A;  4HGU A;  1KMA A;  3TJQ A;  1OYV I;  1M8B A;  1SGY I;  1TUS A;  2LEO A;  3B4V C;  2N17 A;  2NU1 I;  2SGQ I;  4GI3 C;  2GKV A;  2NU3 I;  3SGB I;  1YU6 C;  1UVG A;  1Y1B A;  1CSO I;  1Z7K B;  2V53 A;  2QQC A;  1PCE A;  1NUB A;  1DS2 I;  1OMT A;  1UVF A;  2KMP A;  1TBQ R;  1SGP I;  1MT1 A;  1PPF I;  2XRC A;  1SGN I;  2GKT I;  2KCX A;  1OMU A;  1IY6 A;  1SGD I;  1CT0 I;  2SGF I;  3QTL D;  1HPT A;  1R0R I;  1LR8 A;  2ARP F;  2SGE I;  1SGQ I;  1TBR R;  2NU2 I;  5DAE A;  1CE3 A;  1IW4 A;  1HJA I;  1CHO I;  2BUS A;  1BUS A;  1HDL A;  1CGI I;  1Y1C A;  3SGQ I;  2OVO A;  2JZM A;  2JXD A;  2KMR A;  2F3C I;  2N71 A;  1YTP A;  1AN1 I;  1LR7 A;  2WCY A;  1FYB A;  2P6A C;  2KMO A;  2N52 A;  1IY5 A;  2KMQ A;  1UUC A;  2NU4 I;  4OVO A;  1CT4 I;  1TUR A;  1BMO A;  1SGE I;  1M8C A;  2GKR I;  2SGP I;  1N13 A;  1CGJ I;  2B0U C;  2QQD A;  3OVO A;  1H0Z A;  1TGS I;  4SGB I;  2NU0 I;  1LR9 A;  2ERW A;  1OVO A;  1TIH A;  2JYY A;  2SGD I;  3HH2 C;  5JHW C;  1CT2 I;  3SEK C;  1PJU A;  1SGR I; 
#chains in the Genus database with same CATH topology
 1S20 A;  1TBO A;  3UGI A;  1DS3 I;  1VDD A;  2M5X A;  1RFH A;  4HGU A;  1KMA A;  3TJQ A;  2X52 A;  1OYV I;  4UXJ A;  5E3P A;  5J8C A;  2ODD A;  4UXH A;  1NXU A;  9WGA A;  1M8B A;  2UVO A;  3TOB A;  3VE5 A;  1SGY I;  1PTR A;  2E5R A;  4E1R A;  4B6D A;  1TUS A;  2L8E A;  2LEO A;  2DB6 A;  3B4V C;  2N17 A;  4FKD A;  1TOT A;  1P9G A;  2NU1 I;  1MJ9 A;  2SGQ I;  3QWP A;  4GI3 C;  5E3R A;  5CCL A;  2GKV A;  2ENN A;  3OXG A;  5EX3 A;  2NU3 I;  2YUU A;  3SGB I;  1YU6 C;  1Q9B A;  3OXL A;  3UEY A;  1UVG A;  3E2I A;  2V1C A;  1XBT A;  1CSO I;  1Y1B A;  2JW6 A;  2ROW A;  1Z7K B;  7WGA A;  3UEJ A;  2V53 A;  1K7V A;  2QQ0 A;  2QQC A;  2RIJ A;  2WVJ A;  4E1P A;  2QQE A;  1PCE A;  1NUB A;  2A20 A;  1DS2 I;  2FNF X;  4WP4 A;  2CWG A;  1OMT A;  1U5K A;  1UVF A;  2N1A B;  2KMP A;  1TBQ R;  1X4S A;  2L7X A;  3PDN A;  1SGP I;  5HI7 A;  1MT1 A;  1XX6 A;  1PPF I;  2XRC A;  1KBF A;  1SGN I;  2OZU A;  3R5A A;  3OXF A;  2CWH A;  3FSY A;  3FC3 A;  2OU2 A;  2ENZ A;  1XA6 A;  2GKT I;  1PTQ A;  2KCX A;  3R5D A;  1WTJ A;  5FUY A;  3OL0 A;  1OMU A;  2DKV A;  1IY6 A;  1SGD I;  1K7T A;  1WKX A;  3CXL A;  1CT0 I;  2LUY A;  2SGF I;  3QTL D;  1W3S A;  1V1I A;  1HPT A;  1R0R I;  2QPO A;  1MJA A;  1LR8 A;  2ARP F;  2SGE I;  3UFF A;  1SGQ I;  1TBR R;  1UHA A;  1ULM A;  3RU0 A;  4DNC A;  2NU2 I;  2UZ3 A;  2PQ8 A;  2VRW B;  5DAE A;  1CE3 A;  2X3T A;  1HJA I;  5FUX A;  1IW4 A;  1CHO I;  1FY7 A;  3FSX A;  2BUS A;  1BUS A;  3R5B A;  1HDL A;  1CGI I;  3GOX A;  1FAQ A;  3E59 A;  1Y1C A;  3SGQ I;  1WGC A;  2ORV A;  2OVO A;  1R79 A;  2JZM A;  1ULN A;  5EX0 A;  3BJI A;  2JXD A;  3TOA A;  2KMR A;  4A24 A;  2WGC A;  1FYB A;  2E73 A;  2ORW A;  3TO9 A;  2F3C I;  2YQP A;  2N71 A;  1YTP A;  1AN1 I;  1LR7 A;  1X74 A;  2J87 A;  4JCV E;  3MEK A;  2K9H A;  2WCY A;  2LB7 A;  5FUV A;  2J9R A;  3UOE A;  3TO6 A;  3UGD A;  5CCM A;  1P9Z A;  4UXI A;  2CWF A;  1W4R A;  2P6A C;  5E3Q A;  2KMO A;  2N52 A;  1IY5 A;  2KMQ A;  1UUC A;  2NU4 I;  4OVO A;  1CT4 I;  1TUR A;  3R5C A;  3UGL A;  2OD1 A;  1BMO A;  2GVI A;  1Z2I A;  2V1C C;  2RC4 A;  3VDP A;  1SGE I;  1M8C A;  2GKR I;  3QAH A;  2SGP I;  4AML A;  3TO7 A;  2CJS C;  1HEV A;  3KY9 A;  2B8T A;  5HQ8 A;  5J8F A;  1FAR A;  1TBN A;  1N13 A;  2GIV A;  1CGJ I;  5FUW A;  2B0U C;  3VDU A;  2DIP A;  1KBE A;  2QQD A;  3D00 A;  3OVO A;  1H0Z A;  1Y8F A;  1TGS I;  2W0T A;  4SGB I;  1V1H A;  2NU0 I;  1ULK A;  4MPI A;  1LR9 A;  2ERW A;  1OVO A;  1K7U A;  2Y0M A;  1TIH A;  2JA1 A;  2JYY A;  2SGD I;  3HH2 C;  4L9M A;  5JHW C;  1CT2 I;  2ELI A;  1MJB A;  3SEK C;  1PJU A;  1WGT A;  1SGR I; 
#chains in the Genus database with same CATH homology
 1TBO A;  3UGI A;  1DS3 I;  1VDD A;  2M5X A;  1RFH A;  4HGU A;  1KMA A;  3TJQ A;  1OYV I;  4UXJ A;  2ODD A;  4UXH A;  1M8B A;  3VE5 A;  1SGY I;  1PTR A;  2E5R A;  4E1R A;  4B6D A;  1TUS A;  2L8E A;  2LEO A;  2DB6 A;  3B4V C;  2N17 A;  4FKD A;  1TOT A;  2NU1 I;  2SGQ I;  3QWP A;  5CCL A;  4GI3 C;  2GKV A;  2ENN A;  3OXG A;  5EX3 A;  2NU3 I;  2YUU A;  3SGB I;  1YU6 C;  3UEY A;  3OXL A;  1UVG A;  3E2I A;  2V1C A;  1XBT A;  1CSO I;  1Y1B A;  2JW6 A;  2ROW A;  1Z7K B;  3UEJ A;  2V53 A;  2QQ0 A;  2QQC A;  2WVJ A;  4E1P A;  2QQE A;  1PCE A;  1NUB A;  2A20 A;  1DS2 I;  2FNF X;  2N1A B;  1OMT A;  1U5K A;  1UVF A;  2KMP A;  1TBQ R;  1X4S A;  2L7X A;  3PDN A;  1SGP I;  5HI7 A;  1MT1 A;  1XX6 A;  1PPF I;  2XRC A;  1KBF A;  1SGN I;  3OXF A;  3FC3 A;  2ENZ A;  1XA6 A;  2GKT I;  1PTQ A;  2KCX A;  5FUY A;  3OL0 A;  1OMU A;  1IY6 A;  1SGD I;  3CXL A;  1CT0 I;  2LUY A;  2SGF I;  3QTL D;  1W3S A;  1V1I A;  1HPT A;  1R0R I;  2QPO A;  1LR8 A;  2ARP F;  2SGE I;  3UFF A;  1SGQ I;  1TBR R;  3RU0 A;  2NU2 I;  2UZ3 A;  2VRW B;  5DAE A;  1CE3 A;  1IW4 A;  1HJA I;  5FUX A;  1CHO I;  2BUS A;  1BUS A;  1HDL A;  1CGI I;  3GOX A;  1FAQ A;  3E59 A;  1Y1C A;  3SGQ I;  2ORV A;  2OVO A;  1R79 A;  2JZM A;  5EX0 A;  4A24 A;  3BJI A;  2JXD A;  2KMR A;  2ORW A;  2F3C I;  2YQP A;  2N71 A;  1YTP A;  1AN1 I;  1LR7 A;  1X74 A;  2J87 A;  4JCV E;  3MEK A;  2K9H A;  2WCY A;  5FUV A;  2J9R A;  5CCM A;  3UGD A;  1FYB A;  4UXI A;  2P6A C;  1W4R A;  2KMO A;  2N52 A;  1IY5 A;  2KMQ A;  1UUC A;  2NU4 I;  4OVO A;  1CT4 I;  1TUR A;  3UGL A;  2OD1 A;  1BMO A;  2GVI A;  2V1C C;  3VDP A;  1SGE I;  1M8C A;  2GKR I;  2SGP I;  2CJS C;  3KY9 A;  2B8T A;  5HQ8 A;  1FAR A;  1TBN A;  1N13 A;  5FUW A;  1CGJ I;  3VDU A;  2B0U C;  2DIP A;  1KBE A;  2QQD A;  3D00 A;  3OVO A;  1H0Z A;  1Y8F A;  1TGS I;  2W0T A;  4SGB I;  1V1H A;  2NU0 I;  1LR9 A;  2ERW A;  1OVO A;  1TIH A;  2JA1 A;  2JYY A;  2SGD I;  3HH2 C;  4L9M A;  5JHW C;  1CT2 I;  2ELI A;  3SEK C;  1PJU A;  2E73 A;  1SGR I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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