2F3CI

Crystal structure of infestin 1, a kazal-type serineprotease inhibitor, in complex with trypsin
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
46
structure length
46
Chain Sequence
DCACPRVLHRVCGSDGNTYSNPCTLDCAKHEGKPDLVQVHEGPCDP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Kazal-type inhibitors infestins 1 and 4 differ in specificity but are similar in three-dimensional structure.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Triatoma infestans
molecule keywords Cationic trypsin
total genus 14
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2005-11-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2f3cI00
1CSOI 1LR8A 1LR9A 2P6AC 1CE3A 1SGRI 1Y1BA 1M8CA 2V53A 1OVOA 1PJUA 1SGNI 4SGBI 3SGQI 2NU1I 2SGDI 1CGJI 1DS2I 1CGII 1FYBA 3OVOA 1Z7KB 1SGPI 1SGYI 1UVFA 1M8BA 1YTPA 2N17A 2ARPF 2GKRI 2GKVA 2KCXA 1DS3I 5DAEA 1UVGA 2JYYA 1IY6A 2NU3I 2WCYA 1BUSA 1N13A 2GKTI 4GI3C 2QQCA 2NU0I 3SGBI 1BMOA 2SGPI 1MT1A 2JXDA 1KMAA 1CT2I 1CT4I 2N52A 2LEOA 1OYVI 1HJAI 1H0ZA 2BUSA 1TGSI 2SGFI 3HH2C 2ERWA 3SEKC 2KMPA 3TJQA 2SGEI 2NU2I 1OMUA 1SGQI 1UUCA 3QTLD 1HPTA 1CHOI 2KMRA 2M5XA 1YU6C 2QQDA 2B0UC 1TBQR 2XRCA 1TBRR 1R0RI 1OMTA 1CT0I 1IW4A 1AN1I 1PCEA 1IY5A 1SGDI 1TIHA 1TURA 2SGQI 1TUSA 1PPFI 2KMQA 2KMOA 1Y1CA 4OVOA 5JHWC 1SGEI 2F3CI 1LR7A 2N71A 2JZMA 2OVOA 4HGUA 3B4VC 2NU4I 1HDLA 1NUBA
chains in the Genus database with same CATH superfamily
1XX6A 2ELIA 2RIJA 1XA6A 1V1HA 3D00A 1CSOI 4A24A 2WVJA 1WKXA 2V1CC 1LR8A 2OD1A 4L9MA 4MPIA 1LR9A 2P6AC 2RC4A 1CE3A 3OXFA 1SGRI 1Y1BA 1M8CA 2V53A 2J9RA 1OVOA 1PJUA 2DB6A 1SGNI 4SGBI 3SGQI 2WGCA 2NU1I 1TOTA 2ENNA 3R5AA 3UGDA 2SGDI 1CGJI 2L7XA 1DS2I 1CGII 1KBFA 1WGCA 1Y8FA 2W0TA 1FYBA 2QQEA 1P9ZA 3FC3A 3OVOA 1Z7KB 3QWPA 1SGPI 1SGYI 4JCVE 5EX0A 1UVFA 1M8BA 1YTPA 1TBOA 2N17A 4B6DA 2ARPF 1K7VA 2GKRI 2QPOA 2CWFA 2GKVA 2KCXA 1DS3I 5DAEA 1X4SA 1UVGA 1ULMA 2JYYA 1MJBA 1W3SA 1IY6A 2NU3I 2WCYA 1BUSA 1N13A 2GKTI 4GI3C 9WGAA 3VDUA 1FY7A 2QQCA 2NU0I 4UXIA 3SGBI 1HEVA 3VE5A 4UXHA 1BMOA 2SGPI 1ULKA 1MT1A 2JXDA 1KMAA 1CT2I 3R5CA 1CT4I 2N52A 2LEOA 5CCLA 1OYVI 7WGAA 2B8TA 3OXGA 2L8EA 1HJAI 1H0ZA 2PQ8A 2UZ3A 2BUSA 1MJAA 2CWGA 2GVIA 3TOBA 2ORVA 4UXJA 1TGSI 2E73A 2SGFI 3HH2C 2ERWA 1PTRA 5E3RA 2YQPA 3SEKC 2DIPA 2KMPA 5EX3A 3TJQA 1WTJA 1FAQA 3UGIA 5FUWA 5HI7A 2N1AB 4E1PA 2SGEI 1P9GA 5J8FA 2ODDA 1VDDA 1V1IA 3FSYA 2NU2I 2OU2A 3TO7A 2UVOA 2YUUA 3CXLA 2CJSC 3TO6A 1FARA 3BJIA 1OMUA 1KBEA 5J8CA 1SGQI 2ROWA 1UUCA 3QTLD 3E2IA 1HPTA 1CHOI 1WGTA 2ENZA 3R5BA 2KMRA 1UHAA 3OL0A 2M5XA 3E59A 1YU6C 2K9HA 2QQDA 3KY9A 2OZUA 2B0UC 3FSXA 1TBQR 2XRCA 2A20A 3OXLA 2JW6A 4E1RA 1TBRR 1R0RI 3UEYA 1OMTA 1CT0I 2ORWA 3VDPA 1IW4A 4WP4A 1W4RA 2QQ0A 1AN1I 1K7UA 1PCEA 5E3QA 3UOEA 5HQ8A 1IY5A 2X52A 2E5RA 1SGDI 1TIHA 1TURA 2VRWB 5FUVA 1NXUA 1TUSA 1PPFI 2KMQA 2KMOA 2LUYA 2SGQI 3UEJA 1Y1CA 4DNCA 3UGLA 4OVOA 1RFHA 2Y0MA 1SGEI 1X74A 2F3CI 2JA1A 5JHWC 2J87A 3MEKA 2LB7A 1TBNA 1LR7A 2CWHA 2N71A 5FUXA 1PTQA 3GOXA 3TOAA 3R5DA 1Q9BA 1S20A 1R79A 2JZMA 2V1CA 3PDNA 2OVOA 2GIVA 3QAHA 3UFFA 1K7TA 1Z2IA 4HGUA 5FUYA 3RU0A 3B4VC 5E3PA 2NU4I 1HDLA 4FKDA 2X3TA 1MJ9A 2DKVA 1XBTA 1NUBA 3TO9A 4AMLA 1ULNA 5CCMA 1U5KA 2FNFX
chains in the Genus database with same CATH topology
1XX6A 2ELIA 1XA6A 1V1HA 3D00A 1CSOI 4A24A 2WVJA 2V1CC 1LR8A 2OD1A 4L9MA 1LR9A 2P6AC 1CE3A 3OXFA 1SGRI 1Y1BA 1M8CA 2V53A 2J9RA 1OVOA 1PJUA 2DB6A 1SGNI 4SGBI 3SGQI 2NU1I 1TOTA 2ENNA 2SGDI 1CGJI 2L7XA 1DS2I 1CGII 1KBFA 1Y8FA 2W0TA 1FYBA 2QQEA 3FC3A 3OVOA 1Z7KB 3QWPA 1SGPI 1SGYI 4JCVE 5EX0A 1UVFA 1M8BA 1YTPA 1TBOA 2N17A 4B6DA 2ARPF 2GKRI 2QPOA 2GKVA 2KCXA 1DS3I 5DAEA 1X4SA 1UVGA 2JYYA 1W3SA 1IY6A 2NU3I 2WCYA 1BUSA 1N13A 2GKTI 4GI3C 3VDUA 2QQCA 2NU0I 4UXIA 3SGBI 3VE5A 4UXHA 1BMOA 2SGPI 1MT1A 2JXDA 1KMAA 1CT2I 1CT4I 2N52A 2LEOA 5CCLA 1OYVI 2B8TA 3OXGA 2L8EA 1HJAI 1H0ZA 2UZ3A 2BUSA 2GVIA 2ORVA 4UXJA 1TGSI 2E73A 2SGFI 3HH2C 2ERWA 1PTRA 2YQPA 3SEKC 2DIPA 2KMPA 5EX3A 3TJQA 1FAQA 3UGIA 5FUWA 5HI7A 2N1AB 4E1PA 2SGEI 2ODDA 1VDDA 1V1IA 2NU2I 2YUUA 3CXLA 2CJSC 1FARA 3BJIA 1OMUA 1KBEA 1SGQI 2ROWA 1UUCA 3QTLD 3E2IA 1HPTA 1CHOI 2ENZA 2KMRA 3OL0A 2M5XA 3E59A 1YU6C 2K9HA 2QQDA 3KY9A 2B0UC 1TBQR 2XRCA 2A20A 3OXLA 2JW6A 4E1RA 1TBRR 1R0RI 3UEYA 1OMTA 1CT0I 2ORWA 3VDPA 1IW4A 1W4RA 2QQ0A 1AN1I 1PCEA 5HQ8A 1IY5A 2E5RA 1SGDI 1TIHA 1TURA 2VRWB 5FUVA 2LUYA 1TUSA 1PPFI 2KMQA 2KMOA 2SGQI 3UEJA 1Y1CA 3UGLA 4OVOA 1RFHA 5JHWC 1SGEI 1X74A 2F3CI 2JA1A 2J87A 3MEKA 1TBNA 1LR7A 2N71A 5FUXA 1PTQA 3GOXA 1R79A 2JZMA 2V1CA 3PDNA 2OVOA 3UFFA 4HGUA 5FUYA 3RU0A 3B4VC 2NU4I 1HDLA 4FKDA 1XBTA 1NUBA 3UGDA 5CCMA 1U5KA 2FNFX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CSO I;  1LR8 A;  1LR9 A;  2P6A C;  1CE3 A;  1SGR I;  1Y1B A;  1M8C A;  2V53 A;  1OVO A;  1PJU A;  1SGN I;  4SGB I;  3SGQ I;  2NU1 I;  2SGD I;  1CGJ I;  1DS2 I;  1CGI I;  1FYB A;  3OVO A;  1Z7K B;  1SGP I;  1SGY I;  1UVF A;  1M8B A;  1YTP A;  2N17 A;  2ARP F;  2GKR I;  2GKV A;  2KCX A;  1DS3 I;  5DAE A;  1UVG A;  2JYY A;  1IY6 A;  2NU3 I;  2WCY A;  1BUS A;  1N13 A;  2GKT I;  4GI3 C;  2QQC A;  2NU0 I;  3SGB I;  1BMO A;  2SGP I;  1MT1 A;  2JXD A;  1KMA A;  1CT2 I;  1CT4 I;  2N52 A;  2LEO A;  1OYV I;  1HJA I;  1H0Z A;  2BUS A;  1TGS I;  2SGF I;  3HH2 C;  2ERW A;  3SEK C;  2KMP A;  3TJQ A;  2SGE I;  2NU2 I;  1OMU A;  1SGQ I;  1UUC A;  3QTL D;  1HPT A;  1CHO I;  2KMR A;  2M5X A;  1YU6 C;  2QQD A;  2B0U C;  1TBQ R;  2XRC A;  1TBR R;  1R0R I;  1OMT A;  1CT0 I;  1IW4 A;  1AN1 I;  1PCE A;  1IY5 A;  1SGD I;  1TIH A;  1TUR A;  2SGQ I;  1TUS A;  1PPF I;  2KMQ A;  2KMO A;  1Y1C A;  4OVO A;  5JHW C;  1SGE I;  2F3C I;  1LR7 A;  2N71 A;  2JZM A;  2OVO A;  4HGU A;  3B4V C;  2NU4 I;  1HDL A;  1NUB A; 
#chains in the Genus database with same CATH topology
 1XX6 A;  2ELI A;  2RIJ A;  1XA6 A;  1V1H A;  3D00 A;  1CSO I;  4A24 A;  2WVJ A;  1WKX A;  2V1C C;  1LR8 A;  2OD1 A;  4L9M A;  4MPI A;  1LR9 A;  2P6A C;  2RC4 A;  1CE3 A;  3OXF A;  1SGR I;  1Y1B A;  1M8C A;  2V53 A;  2J9R A;  1OVO A;  1PJU A;  2DB6 A;  1SGN I;  4SGB I;  3SGQ I;  2WGC A;  2NU1 I;  1TOT A;  2ENN A;  3R5A A;  3UGD A;  2SGD I;  1CGJ I;  2L7X A;  1DS2 I;  1CGI I;  1KBF A;  1WGC A;  1Y8F A;  2W0T A;  1FYB A;  2QQE A;  1P9Z A;  3FC3 A;  3OVO A;  1Z7K B;  3QWP A;  1SGP I;  1SGY I;  4JCV E;  5EX0 A;  1UVF A;  1M8B A;  1YTP A;  1TBO A;  2N17 A;  4B6D A;  2ARP F;  1K7V A;  2GKR I;  2QPO A;  2CWF A;  2GKV A;  2KCX A;  1DS3 I;  5DAE A;  1X4S A;  1UVG A;  1ULM A;  2JYY A;  1MJB A;  1W3S A;  1IY6 A;  2NU3 I;  2WCY A;  1BUS A;  1N13 A;  2GKT I;  4GI3 C;  9WGA A;  3VDU A;  1FY7 A;  2QQC A;  2NU0 I;  4UXI A;  3SGB I;  1HEV A;  3VE5 A;  4UXH A;  1BMO A;  2SGP I;  1ULK A;  1MT1 A;  2JXD A;  1KMA A;  1CT2 I;  3R5C A;  1CT4 I;  2N52 A;  2LEO A;  5CCL A;  1OYV I;  7WGA A;  2B8T A;  3OXG A;  2L8E A;  1HJA I;  1H0Z A;  2PQ8 A;  2UZ3 A;  2BUS A;  1MJA A;  2CWG A;  2GVI A;  3TOB A;  2ORV A;  4UXJ A;  1TGS I;  2E73 A;  2SGF I;  3HH2 C;  2ERW A;  1PTR A;  5E3R A;  2YQP A;  3SEK C;  2DIP A;  2KMP A;  5EX3 A;  3TJQ A;  1WTJ A;  1FAQ A;  3UGI A;  5FUW A;  5HI7 A;  2N1A B;  4E1P A;  2SGE I;  1P9G A;  5J8F A;  2ODD A;  1VDD A;  1V1I A;  3FSY A;  2NU2 I;  2OU2 A;  3TO7 A;  2UVO A;  2YUU A;  3CXL A;  2CJS C;  3TO6 A;  1FAR A;  3BJI A;  1OMU A;  1KBE A;  5J8C A;  1SGQ I;  2ROW A;  1UUC A;  3QTL D;  3E2I A;  1HPT A;  1CHO I;  1WGT A;  2ENZ A;  3R5B A;  2KMR A;  1UHA A;  3OL0 A;  2M5X A;  3E59 A;  1YU6 C;  2K9H A;  2QQD A;  3KY9 A;  2OZU A;  2B0U C;  3FSX A;  1TBQ R;  2XRC A;  2A20 A;  3OXL A;  2JW6 A;  4E1R A;  1TBR R;  1R0R I;  3UEY A;  1OMT A;  1CT0 I;  2ORW A;  3VDP A;  1IW4 A;  4WP4 A;  1W4R A;  2QQ0 A;  1AN1 I;  1K7U A;  1PCE A;  5E3Q A;  3UOE A;  5HQ8 A;  1IY5 A;  2X52 A;  2E5R A;  1SGD I;  1TIH A;  1TUR A;  2VRW B;  5FUV A;  1NXU A;  1TUS A;  1PPF I;  2KMQ A;  2KMO A;  2LUY A;  2SGQ I;  3UEJ A;  1Y1C A;  4DNC A;  3UGL A;  4OVO A;  1RFH A;  2Y0M A;  1SGE I;  1X74 A;  2F3C I;  2JA1 A;  5JHW C;  2J87 A;  3MEK A;  2LB7 A;  1TBN A;  1LR7 A;  2CWH A;  2N71 A;  5FUX A;  1PTQ A;  3GOX A;  3TOA A;  3R5D A;  1Q9B A;  1S20 A;  1R79 A;  2JZM A;  2V1C A;  3PDN A;  2OVO A;  2GIV A;  3QAH A;  3UFF A;  1K7T A;  1Z2I A;  4HGU A;  5FUY A;  3RU0 A;  3B4V C;  5E3P A;  2NU4 I;  1HDL A;  4FKD A;  2X3T A;  1MJ9 A;  2DKV A;  1XBT A;  1NUB A;  3TO9 A;  4AML A;  1ULN A;  5CCM A;  1U5K A;  2FNF X; 
#chains in the Genus database with same CATH homology
 1XX6 A;  2ELI A;  1XA6 A;  1V1H A;  3D00 A;  1CSO I;  4A24 A;  2WVJ A;  2V1C C;  1LR8 A;  2OD1 A;  4L9M A;  1LR9 A;  2P6A C;  1CE3 A;  3OXF A;  1SGR I;  1Y1B A;  1M8C A;  2V53 A;  2J9R A;  1OVO A;  1PJU A;  2DB6 A;  1SGN I;  4SGB I;  3SGQ I;  2NU1 I;  1TOT A;  2ENN A;  2SGD I;  1CGJ I;  2L7X A;  1DS2 I;  1CGI I;  1KBF A;  1Y8F A;  2W0T A;  1FYB A;  2QQE A;  3FC3 A;  3OVO A;  1Z7K B;  3QWP A;  1SGP I;  1SGY I;  4JCV E;  5EX0 A;  1UVF A;  1M8B A;  1YTP A;  1TBO A;  2N17 A;  4B6D A;  2ARP F;  2GKR I;  2QPO A;  2GKV A;  2KCX A;  1DS3 I;  5DAE A;  1X4S A;  1UVG A;  2JYY A;  1W3S A;  1IY6 A;  2NU3 I;  2WCY A;  1BUS A;  1N13 A;  2GKT I;  4GI3 C;  3VDU A;  2QQC A;  2NU0 I;  4UXI A;  3SGB I;  3VE5 A;  4UXH A;  1BMO A;  2SGP I;  1MT1 A;  2JXD A;  1KMA A;  1CT2 I;  1CT4 I;  2N52 A;  2LEO A;  5CCL A;  1OYV I;  2B8T A;  3OXG A;  2L8E A;  1HJA I;  1H0Z A;  2UZ3 A;  2BUS A;  2GVI A;  2ORV A;  4UXJ A;  1TGS I;  2E73 A;  2SGF I;  3HH2 C;  2ERW A;  1PTR A;  2YQP A;  3SEK C;  2DIP A;  2KMP A;  5EX3 A;  3TJQ A;  1FAQ A;  3UGI A;  5FUW A;  5HI7 A;  2N1A B;  4E1P A;  2SGE I;  2ODD A;  1VDD A;  1V1I A;  2NU2 I;  2YUU A;  3CXL A;  2CJS C;  1FAR A;  3BJI A;  1OMU A;  1KBE A;  1SGQ I;  2ROW A;  1UUC A;  3QTL D;  3E2I A;  1HPT A;  1CHO I;  2ENZ A;  2KMR A;  3OL0 A;  2M5X A;  3E59 A;  1YU6 C;  2K9H A;  2QQD A;  3KY9 A;  2B0U C;  1TBQ R;  2XRC A;  2A20 A;  3OXL A;  2JW6 A;  4E1R A;  1TBR R;  1R0R I;  3UEY A;  1OMT A;  1CT0 I;  2ORW A;  3VDP A;  1IW4 A;  1W4R A;  2QQ0 A;  1AN1 I;  1PCE A;  5HQ8 A;  1IY5 A;  2E5R A;  1SGD I;  1TIH A;  1TUR A;  2VRW B;  5FUV A;  2LUY A;  1TUS A;  1PPF I;  2KMQ A;  2KMO A;  2SGQ I;  3UEJ A;  1Y1C A;  3UGL A;  4OVO A;  1RFH A;  5JHW C;  1SGE I;  1X74 A;  2F3C I;  2JA1 A;  2J87 A;  3MEK A;  1TBN A;  1LR7 A;  2N71 A;  5FUX A;  1PTQ A;  3GOX A;  1R79 A;  2JZM A;  2V1C A;  3PDN A;  2OVO A;  3UFF A;  4HGU A;  5FUY A;  3RU0 A;  3B4V C;  2NU4 I;  1HDL A;  4FKD A;  1XBT A;  1NUB A;  3UGD A;  5CCM A;  1U5K A;  2FNF X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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