2JXDA

Nmr structure of human serine protease inhibitor kazal type ii (spink2)
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
62
structure length
62
Chain Sequence
PQFGLFSKYRTPNCSQYRLPGCPRHFNPVCGSDMSTYANECTLCMKIREGGHNIKIIRNGPC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of trypsin-inhibitory site and structure determination of human SPINK2 serine proteinase inhibitor
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Homo sapiens
molecule keywords Serine protease inhibitor Kazal-type 2
total genus 9
structure length 62
sequence length 62
ec nomenclature
pdb deposition date 2007-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2jxdA00
1CGII 4SGBI 2M5XA 1N13A 2GKVA 1R0RI 1BUSA 5JHWC 2GKTI 2XRCA 2V53A 1Y1BA 1IY5A 1PPFI 1OMUA 1SGQI 1HJAI 3SEKC 1M8CA 1SGPI 1MT1A 1UUCA 1IY6A 2LEOA 3HH2C 1CT2I 1H0ZA 1OMTA 1CHOI 1IW4A 1NUBA 1CGJI 3OVOA 2BUSA 2B0UC 2N17A 2KMPA 2JZMA 2SGDI 2N71A 1HDLA 1TUSA 1LR7A 2KCXA 1YU6C 2F3CI 2SGFI 1OYVI 2GKRI 4GI3C 1SGYI 2KMRA 2SGPI 2SGEI 3B4VC 1CSOI 2ERWA 2N52A 1HPTA 1OVOA 1UVFA 1BMOA 3QTLD 1SGEI 1KMAA 4OVOA 2NU0I 1TBQR 2JXDA 2QQDA 1SGDI 1TBRR 1YTPA 1DS2I 1LR8A 1FYBA 5DAEA 2WCYA 1TURA 2KMQA 1CT4I 1M8BA 1TGSI 2OVOA 2SGQI 1AN1I 1TIHA 2NU3I 2NU4I 1SGRI 2NU2I 1PCEA 2KMOA 1UVGA 4HGUA 2P6AC 1Z7KB 2ARPF 1DS3I 2QQCA 3SGBI 3TJQA 1LR9A 1Y1CA 2JYYA 2NU1I 3SGQI 1CE3A 1PJUA 1CT0I 1SGNI
chains in the Genus database with same CATH superfamily
1CGII 4SGBI 2M5XA 1N13A 2FNFX 2GKVA 1R0RI 4E1RA 3UOEA 1TOTA 1BUSA 2CWHA 1WKXA 5JHWC 2GKTI 3VDUA 2XRCA 2V53A 1Y1BA 1WTJA 2OU2A 2WVJA 4DNCA 2N1AB 3GOXA 2QQEA 2X3TA 1IY5A 1PPFI 2L7XA 1OMUA 2ODDA 1P9GA 1SGQI 3VDPA 2CJSC 1HJAI 3R5BA 5E3RA 1M8CA 3SEKC 2WGCA 1SGPI 3E59A 2CWGA 1MT1A 1V1HA 3PDNA 1UUCA 5E3PA 1FARA 2GVIA 1IY6A 2E73A 2ORWA 1ULKA 1K7TA 2LEOA 2CWFA 3HH2C 3TOBA 3TO7A 1VDDA 1CT2I 2W0TA 1WGCA 1H0ZA 1OMTA 3TO9A 1CHOI 7WGAA 1ULMA 1XX6A 1NUBA 5FUWA 2ORVA 1IW4A 1CGJI 2Y0MA 3OVOA 2OZUA 3UGLA 2BUSA 2UVOA 2B0UC 2N17A 1MJBA 2QPOA 2KMPA 1XA6A 1XBTA 3RU0A 2K9HA 2JZMA 1R79A 4WP4A 5J8CA 1FY7A 2SGDI 5FUVA 1PTQA 2GIVA 2N71A 3FSXA 3R5AA 1HDLA 1TUSA 1KBEA 5HI7A 1LR7A 2ELIA 2KCXA 1WGTA 1YU6C 2F3CI 2SGFI 2ENZA 2V1CC 4B6DA 1OYVI 2E5RA 2B8TA 2J9RA 2GKRI 3OXLA 4GI3C 2OD1A 1SGYI 3D00A 2JW6A 2KMRA 2SGPI 2SGEI 3B4VC 1CSOI 1S20A 3BJIA 1Q9BA 2ERWA 2N52A 1FAQA 1X74A 2JA1A 1HPTA 1OVOA 2QQ0A 2ROWA 1UVFA 1NXUA 3OXFA 1BMOA 3QTLD 3TO6A 1SGEI 1KMAA 2DB6A 1ULNA 4OVOA 5FUYA 2X52A 5E3QA 2NU0I 1TBQR 1V1IA 2JXDA 1Z2IA 2DIPA 2QQDA 3TOAA 1SGDI 1MJ9A 1TBRR 1TBNA 1YTPA 3QAHA 1DS2I 4JCVE 5EX0A 1LR8A 1FYBA 4E1PA 5DAEA 1P9ZA 1RFHA 3OL0A 4L9MA 4MPIA 5FUXA 3UFFA 5CCMA 2WCYA 1TURA 2KMQA 1CT4I 3R5CA 1M8BA 1TGSI 1MJAA 1PTRA 3CXLA 3KY9A 2OVOA 3R5DA 1U5KA 1K7VA 5EX3A 2SGQI 5CCLA 1AN1I 4A24A 1TIHA 1UHAA 2YQPA 1K7UA 1TBOA 2NU3I 3MEKA 4UXIA 2YUUA 2NU4I 2VRWB 4UXJA 3UEJA 1KBFA 1SGRI 2A20A 2NU2I 1W4RA 2PQ8A 5HQ8A 1PCEA 4FKDA 2KMOA 5J8FA 3QWPA 1UVGA 3OXGA 4HGUA 2P6AC 1HEVA 1Z7KB 2ARPF 1DS3I 2J87A 2UZ3A 2LB7A 3UEYA 2QQCA 3SGBI 3VE5A 2RIJA 1X4SA 3FSYA 3TJQA 2DKVA 1LR9A 9WGAA 1Y1CA 2JYYA 3UGIA 2V1CA 3UGDA 3FC3A 2NU1I 1W3SA 3E2IA 2ENNA 2L8EA 4UXHA 3SGQI 4AMLA 1Y8FA 1PJUA 2RC4A 1CE3A 2LUYA 1CT0I 1SGNI
chains in the Genus database with same CATH topology
1CGII 4SGBI 2M5XA 1N13A 2FNFX 2GKVA 1R0RI 4E1RA 1TOTA 1BUSA 5JHWC 2GKTI 3VDUA 2XRCA 2V53A 1Y1BA 1IY5A 2WVJA 2N1AB 3GOXA 2QQEA 1PPFI 2L7XA 1OMUA 2ODDA 1SGQI 3VDPA 2CJSC 1HJAI 3SEKC 1M8CA 1SGPI 3E59A 1MT1A 1V1HA 3PDNA 1UUCA 1FARA 2GVIA 1IY6A 2E73A 2ORWA 2LEOA 3HH2C 1VDDA 1CT2I 2W0TA 1H0ZA 1OMTA 1CHOI 1XX6A 1NUBA 5FUWA 2ORVA 1IW4A 1CGJI 3OVOA 3UGLA 2BUSA 2B0UC 2N17A 2QPOA 2KMPA 1XA6A 1XBTA 3RU0A 2K9HA 2JZMA 1R79A 2SGDI 5FUVA 1PTQA 2N71A 1HDLA 1TUSA 1KBEA 5HI7A 1LR7A 2ELIA 2KCXA 1YU6C 2F3CI 2SGFI 2ENZA 2V1CC 4B6DA 1OYVI 2E5RA 2B8TA 2J9RA 2GKRI 3OXLA 4GI3C 2OD1A 1SGYI 3D00A 2JW6A 2KMRA 2SGPI 2SGEI 3B4VC 1CSOI 3BJIA 2ERWA 2N52A 1FAQA 1X74A 2JA1A 1HPTA 1OVOA 2QQ0A 2ROWA 1UVFA 3OXFA 1BMOA 3QTLD 1SGEI 1KMAA 2DB6A 4OVOA 5FUYA 2NU0I 1TBQR 1V1IA 2JXDA 2DIPA 2QQDA 1SGDI 1YTPA 1TBRR 1TBNA 5EX0A 1DS2I 4JCVE 1LR8A 1FYBA 4E1PA 5DAEA 3OL0A 1RFHA 4L9MA 5FUXA 3UFFA 5CCMA 2WCYA 1TURA 2KMQA 1CT4I 1M8BA 1TGSI 1PTRA 3KY9A 3CXLA 2OVOA 1U5KA 5EX3A 2SGQI 5CCLA 1AN1I 4A24A 1TIHA 2YQPA 1TBOA 2NU3I 3MEKA 4UXIA 2YUUA 2NU4I 2VRWB 4UXJA 3UEJA 1KBFA 1SGRI 2A20A 2NU2I 1W4RA 5HQ8A 1PCEA 4FKDA 2KMOA 3QWPA 1UVGA 3OXGA 4HGUA 2P6AC 1Z7KB 2ARPF 1DS3I 2J87A 2UZ3A 3UEYA 2QQCA 3SGBI 3VE5A 1X4SA 3TJQA 1LR9A 1Y1CA 2JYYA 3UGIA 2V1CA 3UGDA 2NU1I 1W3SA 3E2IA 2ENNA 2L8EA 4UXHA 3SGQI 3FC3A 1Y8FA 1PJUA 1CE3A 2LUYA 1CT0I 1SGNI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CGI I;  4SGB I;  2M5X A;  1N13 A;  2GKV A;  1R0R I;  1BUS A;  5JHW C;  2GKT I;  2XRC A;  2V53 A;  1Y1B A;  1IY5 A;  1PPF I;  1OMU A;  1SGQ I;  1HJA I;  3SEK C;  1M8C A;  1SGP I;  1MT1 A;  1UUC A;  1IY6 A;  2LEO A;  3HH2 C;  1CT2 I;  1H0Z A;  1OMT A;  1CHO I;  1IW4 A;  1NUB A;  1CGJ I;  3OVO A;  2BUS A;  2B0U C;  2N17 A;  2KMP A;  2JZM A;  2SGD I;  2N71 A;  1HDL A;  1TUS A;  1LR7 A;  2KCX A;  1YU6 C;  2F3C I;  2SGF I;  1OYV I;  2GKR I;  4GI3 C;  1SGY I;  2KMR A;  2SGP I;  2SGE I;  3B4V C;  1CSO I;  2ERW A;  2N52 A;  1HPT A;  1OVO A;  1UVF A;  1BMO A;  3QTL D;  1SGE I;  1KMA A;  4OVO A;  2NU0 I;  1TBQ R;  2JXD A;  2QQD A;  1SGD I;  1TBR R;  1YTP A;  1DS2 I;  1LR8 A;  1FYB A;  5DAE A;  2WCY A;  1TUR A;  2KMQ A;  1CT4 I;  1M8B A;  1TGS I;  2OVO A;  2SGQ I;  1AN1 I;  1TIH A;  2NU3 I;  2NU4 I;  1SGR I;  2NU2 I;  1PCE A;  2KMO A;  1UVG A;  4HGU A;  2P6A C;  1Z7K B;  2ARP F;  1DS3 I;  2QQC A;  3SGB I;  3TJQ A;  1LR9 A;  1Y1C A;  2JYY A;  2NU1 I;  3SGQ I;  1CE3 A;  1PJU A;  1CT0 I;  1SGN I; 
#chains in the Genus database with same CATH topology
 1CGI I;  4SGB I;  2M5X A;  1N13 A;  2FNF X;  2GKV A;  1R0R I;  4E1R A;  3UOE A;  1TOT A;  1BUS A;  2CWH A;  1WKX A;  5JHW C;  2GKT I;  3VDU A;  2XRC A;  2V53 A;  1Y1B A;  1WTJ A;  2OU2 A;  2WVJ A;  4DNC A;  2N1A B;  3GOX A;  2QQE A;  2X3T A;  1IY5 A;  1PPF I;  2L7X A;  1OMU A;  2ODD A;  1P9G A;  1SGQ I;  3VDP A;  2CJS C;  1HJA I;  3R5B A;  5E3R A;  1M8C A;  3SEK C;  2WGC A;  1SGP I;  3E59 A;  2CWG A;  1MT1 A;  1V1H A;  3PDN A;  1UUC A;  5E3P A;  1FAR A;  2GVI A;  1IY6 A;  2E73 A;  2ORW A;  1ULK A;  1K7T A;  2LEO A;  2CWF A;  3HH2 C;  3TOB A;  3TO7 A;  1VDD A;  1CT2 I;  2W0T A;  1WGC A;  1H0Z A;  1OMT A;  3TO9 A;  1CHO I;  7WGA A;  1ULM A;  1XX6 A;  1NUB A;  5FUW A;  2ORV A;  1IW4 A;  1CGJ I;  2Y0M A;  3OVO A;  2OZU A;  3UGL A;  2BUS A;  2UVO A;  2B0U C;  2N17 A;  1MJB A;  2QPO A;  2KMP A;  1XA6 A;  1XBT A;  3RU0 A;  2K9H A;  2JZM A;  1R79 A;  4WP4 A;  5J8C A;  1FY7 A;  2SGD I;  5FUV A;  1PTQ A;  2GIV A;  2N71 A;  3FSX A;  3R5A A;  1HDL A;  1TUS A;  1KBE A;  5HI7 A;  1LR7 A;  2ELI A;  2KCX A;  1WGT A;  1YU6 C;  2F3C I;  2SGF I;  2ENZ A;  2V1C C;  4B6D A;  1OYV I;  2E5R A;  2B8T A;  2J9R A;  2GKR I;  3OXL A;  4GI3 C;  2OD1 A;  1SGY I;  3D00 A;  2JW6 A;  2KMR A;  2SGP I;  2SGE I;  3B4V C;  1CSO I;  1S20 A;  3BJI A;  1Q9B A;  2ERW A;  2N52 A;  1FAQ A;  1X74 A;  2JA1 A;  1HPT A;  1OVO A;  2QQ0 A;  2ROW A;  1UVF A;  1NXU A;  3OXF A;  1BMO A;  3QTL D;  3TO6 A;  1SGE I;  1KMA A;  2DB6 A;  1ULN A;  4OVO A;  5FUY A;  2X52 A;  5E3Q A;  2NU0 I;  1TBQ R;  1V1I A;  2JXD A;  1Z2I A;  2DIP A;  2QQD A;  3TOA A;  1SGD I;  1MJ9 A;  1TBR R;  1TBN A;  1YTP A;  3QAH A;  1DS2 I;  4JCV E;  5EX0 A;  1LR8 A;  1FYB A;  4E1P A;  5DAE A;  1P9Z A;  1RFH A;  3OL0 A;  4L9M A;  4MPI A;  5FUX A;  3UFF A;  5CCM A;  2WCY A;  1TUR A;  2KMQ A;  1CT4 I;  3R5C A;  1M8B A;  1TGS I;  1MJA A;  1PTR A;  3CXL A;  3KY9 A;  2OVO A;  3R5D A;  1U5K A;  1K7V A;  5EX3 A;  2SGQ I;  5CCL A;  1AN1 I;  4A24 A;  1TIH A;  1UHA A;  2YQP A;  1K7U A;  1TBO A;  2NU3 I;  3MEK A;  4UXI A;  2YUU A;  2NU4 I;  2VRW B;  4UXJ A;  3UEJ A;  1KBF A;  1SGR I;  2A20 A;  2NU2 I;  1W4R A;  2PQ8 A;  5HQ8 A;  1PCE A;  4FKD A;  2KMO A;  5J8F A;  3QWP A;  1UVG A;  3OXG A;  4HGU A;  2P6A C;  1HEV A;  1Z7K B;  2ARP F;  1DS3 I;  2J87 A;  2UZ3 A;  2LB7 A;  3UEY A;  2QQC A;  3SGB I;  3VE5 A;  2RIJ A;  1X4S A;  3FSY A;  3TJQ A;  2DKV A;  1LR9 A;  9WGA A;  1Y1C A;  2JYY A;  3UGI A;  2V1C A;  3UGD A;  3FC3 A;  2NU1 I;  1W3S A;  3E2I A;  2ENN A;  2L8E A;  4UXH A;  3SGQ I;  4AML A;  1Y8F A;  1PJU A;  2RC4 A;  1CE3 A;  2LUY A;  1CT0 I;  1SGN I; 
#chains in the Genus database with same CATH homology
 1CGI I;  4SGB I;  2M5X A;  1N13 A;  2FNF X;  2GKV A;  1R0R I;  4E1R A;  1TOT A;  1BUS A;  5JHW C;  2GKT I;  3VDU A;  2XRC A;  2V53 A;  1Y1B A;  1IY5 A;  2WVJ A;  2N1A B;  3GOX A;  2QQE A;  1PPF I;  2L7X A;  1OMU A;  2ODD A;  1SGQ I;  3VDP A;  2CJS C;  1HJA I;  3SEK C;  1M8C A;  1SGP I;  3E59 A;  1MT1 A;  1V1H A;  3PDN A;  1UUC A;  1FAR A;  2GVI A;  1IY6 A;  2E73 A;  2ORW A;  2LEO A;  3HH2 C;  1VDD A;  1CT2 I;  2W0T A;  1H0Z A;  1OMT A;  1CHO I;  1XX6 A;  1NUB A;  5FUW A;  2ORV A;  1IW4 A;  1CGJ I;  3OVO A;  3UGL A;  2BUS A;  2B0U C;  2N17 A;  2QPO A;  2KMP A;  1XA6 A;  1XBT A;  3RU0 A;  2K9H A;  2JZM A;  1R79 A;  2SGD I;  5FUV A;  1PTQ A;  2N71 A;  1HDL A;  1TUS A;  1KBE A;  5HI7 A;  1LR7 A;  2ELI A;  2KCX A;  1YU6 C;  2F3C I;  2SGF I;  2ENZ A;  2V1C C;  4B6D A;  1OYV I;  2E5R A;  2B8T A;  2J9R A;  2GKR I;  3OXL A;  4GI3 C;  2OD1 A;  1SGY I;  3D00 A;  2JW6 A;  2KMR A;  2SGP I;  2SGE I;  3B4V C;  1CSO I;  3BJI A;  2ERW A;  2N52 A;  1FAQ A;  1X74 A;  2JA1 A;  1HPT A;  1OVO A;  2QQ0 A;  2ROW A;  1UVF A;  3OXF A;  1BMO A;  3QTL D;  1SGE I;  1KMA A;  2DB6 A;  4OVO A;  5FUY A;  2NU0 I;  1TBQ R;  1V1I A;  2JXD A;  2DIP A;  2QQD A;  1SGD I;  1YTP A;  1TBR R;  1TBN A;  5EX0 A;  1DS2 I;  4JCV E;  1LR8 A;  1FYB A;  4E1P A;  5DAE A;  3OL0 A;  1RFH A;  4L9M A;  5FUX A;  3UFF A;  5CCM A;  2WCY A;  1TUR A;  2KMQ A;  1CT4 I;  1M8B A;  1TGS I;  1PTR A;  3KY9 A;  3CXL A;  2OVO A;  1U5K A;  5EX3 A;  2SGQ I;  5CCL A;  1AN1 I;  4A24 A;  1TIH A;  2YQP A;  1TBO A;  2NU3 I;  3MEK A;  4UXI A;  2YUU A;  2NU4 I;  2VRW B;  4UXJ A;  3UEJ A;  1KBF A;  1SGR I;  2A20 A;  2NU2 I;  1W4R A;  5HQ8 A;  1PCE A;  4FKD A;  2KMO A;  3QWP A;  1UVG A;  3OXG A;  4HGU A;  2P6A C;  1Z7K B;  2ARP F;  1DS3 I;  2J87 A;  2UZ3 A;  3UEY A;  2QQC A;  3SGB I;  3VE5 A;  1X4S A;  3TJQ A;  1LR9 A;  1Y1C A;  2JYY A;  3UGI A;  2V1C A;  3UGD A;  2NU1 I;  1W3S A;  3E2I A;  2ENN A;  2L8E A;  4UXH A;  3SGQ I;  3FC3 A;  1Y8F A;  1PJU A;  1CE3 A;  2LUY A;  1CT0 I;  1SGN I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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