2KCXA

Solution nmr structure of kazal-1 domain of human follistatin-related protein 3 (fstl-3). northeast structural genomics target hr6186a.
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
74
structure length
74
Chain Sequence
SDSCDGVECGPGKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAARCRGHPDLSVMYRGRCRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution NMR Structure of Kazal-1 Domain of Human Follistatin-related protein 3 (FSTL-3). Northeast Structural Genomics Target HR6186A.
rcsb
molecule tags Structural genomics, unknown function
source organism Homo sapiens
molecule keywords Follistatin-related protein 3
total genus 14
structure length 74
sequence length 74
ec nomenclature
pdb deposition date 2008-12-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07648 Kazal_2 Kazal-type serine protease inhibitor domain
A PF09289 FOLN Follistatin/Osteonectin-like EGF domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2kcxA00
1DS3I 1YTPA 4GI3C 1MT1A 1Z7KB 2N52A 3TJQA 1CGJI 2SGDI 1UVGA 1TGSI 1H0ZA 2XRCA 1TBQR 4OVOA 1KMAA 1SGNI 1CT0I 2GKTI 1SGDI 1PCEA 2KMOA 2NU4I 1CHOI 2KMPA 1SGEI 2SGFI 3OVOA 2KMQA 1Y1CA 1CGII 1LR8A 1BUSA 2SGQI 1PJUA 1CSOI 1NUBA 3SGQI 1CT2I 2V53A 2M5XA 1UVFA 1TURA 2NU0I 1LR7A 1OYVI 1OMTA 4HGUA 2F3CI 2NU2I 5DAEA 1IY5A 1HJAI 1OMUA 2GKVA 2ARPF 1CT4I 3QTLD 3B4VC 1UUCA 1IW4A 1M8BA 2KMRA 2N71A 1PPFI 1SGQI 2SGEI 1OVOA 1TUSA 2JZMA 1LR9A 2GKRI 1HDLA 1BMOA 1CE3A 2B0UC 2BUSA 2SGPI 1YU6C 2P6AC 1Y1BA 1HPTA 1TIHA 2N17A 4SGBI 1R0RI 1M8CA 3SEKC 1DS2I 2NU3I 2WCYA 2QQDA 5JHWC 2KCXA 1SGYI 2JXDA 2LEOA 1TBRR 2JYYA 1AN1I 1FYBA 2NU1I 1N13A 3HH2C 1SGRI 1IY6A 2ERWA 3SGBI 1SGPI 2OVOA 2QQCA
chains in the Genus database with same CATH superfamily
3UFFA 2ENNA 1DS3I 2OVOA 1YTPA 4GI3C 5FUXA 3UEJA 2J87A 1MT1A 3MEKA 1Z7KB 3FSYA 5E3QA 1TBOA 2N52A 2VRWB 3TJQA 1CGJI 2SGDI 1UVGA 1TGSI 3PDNA 1H0ZA 2XRCA 1TBQR 1V1HA 3VE5A 5FUVA 4JCVE 4OVOA 1XBTA 1RFHA 1KMAA 1SGNI 1CT0I 3E59A 7WGAA 1X4SA 2GKTI 2J9RA 1SGDI 1P9ZA 1PCEA 1ULMA 1X74A 2KMOA 1XX6A 2E5RA 3OXFA 4DNCA 2NU4I 1CHOI 1NXUA 2DKVA 2KMPA 1W3SA 1SGEI 2K9HA 3VDPA 2SGFI 1FY7A 3OVOA 2KMQA 1MJBA 1Y1CA 1CGII 1K7TA 2QQ0A 2YUUA 1LR8A 3R5DA 2CWGA 1BUSA 3UGDA 3UOEA 4WP4A 2LB7A 2OZUA 5HQ8A 5CCMA 1Y8FA 2SGQI 1PJUA 2GVIA 1UHAA 1MJAA 3E2IA 1CSOI 2V1CA 1NUBA 3SGQI 1CT2I 3TO7A 2ELIA 1K7VA 2M5XA 2V53A 1R79A 1UVFA 2X52A 3D00A 5FUYA 1FAQA 1TURA 2NU0I 1LR7A 1PTRA 4A24A 2GIVA 2RIJA 2OD1A 1HEVA 2OU2A 1OYVI 1OMTA 4HGUA 1TBNA 2F3CI 2NU2I 1U5KA 5DAEA 1IY5A 1HJAI 2PQ8A 1OMUA 3OXLA 2GKVA 3OXGA 3GOXA 2ROWA 4AMLA 2ARPF 1CT4I 1Q9BA 1KBEA 1ULNA 3BJIA 3OL0A 3QTLD 3RU0A 2A20A 3FC3A 2CWHA 5EX0A 4FKDA 3B4VC 1WGTA 1K7UA 3QWPA 3R5BA 1UUCA 3QAHA 2YQPA 5J8CA 1WGCA 1M8BA 1IW4A 2KMRA 2N71A 1PPFI 1SGQI 2SGEI 3R5CA 2ENZA 3UGIA 3KY9A 2RC4A 1MJ9A 1OVOA 1VDDA 2WGCA 1TUSA 2L8EA 1ULKA 2JZMA 3TOBA 5FUWA 1LR9A 2GKRI 2ORWA 1HDLA 1BMOA 2LUYA 3R5AA 5CCLA 2ORVA 3TOAA 1CE3A 2B0UC 2BUSA 2W0TA 3TO9A 3UEYA 2N1AB 4UXHA 2SGPI 1YU6C 1WTJA 1Z2IA 2B8TA 1P9GA 2P6AC 1KBFA 2ODDA 1WKXA 1Y1BA 1HPTA 1TIHA 1V1IA 2N17A 2E73A 2L7XA 4SGBI 2CWFA 1R0RI 1M8CA 2QPOA 3SEKC 1FARA 1DS2I 2DB6A 4E1PA 2NU3I 2WCYA 2QQDA 2V1CC 5JHWC 2DIPA 2KCXA 1SGYI 2UZ3A 5E3RA 9WGAA 1XA6A 2JXDA 2WVJA 2FNFX 5J8FA 3TO6A 2X3TA 2LEOA 4UXIA 1TBRR 2JYYA 3FSXA 4MPIA 1AN1I 1FYBA 4B6DA 2NU1I 4UXJA 2Y0MA 1N13A 1PTQA 1TOTA 3HH2C 1S20A 1SGRI 2CJSC 2JW6A 3UGLA 2ERWA 3VDUA 1IY6A 5EX3A 4E1RA 3CXLA 1W4RA 2QQEA 5E3PA 4L9MA 2UVOA 3SGBI 5HI7A 1SGPI 2JA1A 2QQCA
chains in the Genus database with same CATH topology
3UFFA 2ENNA 1DS3I 2OVOA 1YTPA 4GI3C 5FUXA 2J87A 1MT1A 3MEKA 1Z7KB 1TBOA 2N52A 2VRWB 3TJQA 1CGJI 2SGDI 1UVGA 1TGSI 3PDNA 1H0ZA 2XRCA 1TBQR 1V1HA 3VE5A 5FUVA 4JCVE 4OVOA 1XBTA 1RFHA 1KMAA 1SGNI 1CT0I 3E59A 1X4SA 2GKTI 2J9RA 1SGDI 1PCEA 2KMOA 1X74A 3OXFA 3UEJA 1XX6A 2E5RA 2NU4I 1CHOI 2KMPA 1W3SA 1SGEI 2K9HA 3VDPA 2SGFI 3OVOA 2KMQA 1Y1CA 1CGII 2QQ0A 2YUUA 1LR8A 1BUSA 3UGDA 5HQ8A 5CCMA 1Y8FA 2SGQI 1PJUA 2GVIA 3E2IA 1CSOI 2V1CA 1NUBA 3SGQI 1CT2I 2ELIA 2V53A 2M5XA 3D00A 1R79A 1UVFA 5FUYA 1FAQA 1TURA 2NU0I 1LR7A 1PTRA 4A24A 2OD1A 1OYVI 1OMTA 4HGUA 1TBNA 2F3CI 2NU2I 1U5KA 5DAEA 1IY5A 1HJAI 1OMUA 3OXLA 2GKVA 3OXGA 3GOXA 2ROWA 2ARPF 1CT4I 3BJIA 1KBEA 3OL0A 3RU0A 3QTLD 3FC3A 2A20A 5EX0A 4FKDA 3B4VC 3QWPA 1UUCA 1IW4A 2YQPA 1M8BA 2KMRA 2N71A 1PPFI 1SGQI 2SGEI 2ENZA 3UGIA 3KY9A 1VDDA 1OVOA 1TUSA 2L8EA 2JZMA 5FUWA 1LR9A 2GKRI 2ORWA 1HDLA 1BMOA 2LUYA 5CCLA 2ORVA 1CE3A 2B0UC 2BUSA 2W0TA 3UEYA 2N1AB 4UXHA 2SGPI 1YU6C 2B8TA 2P6AC 1KBFA 2ODDA 1Y1BA 1HPTA 1TIHA 1V1IA 2N17A 2E73A 2L7XA 4SGBI 2QPOA 1R0RI 1M8CA 3SEKC 1FARA 1DS2I 2DB6A 4E1PA 2NU3I 2WCYA 2QQDA 2V1CC 5JHWC 2DIPA 2KCXA 1SGYI 2UZ3A 1XA6A 2JXDA 2WVJA 2FNFX 2LEOA 4UXIA 1TBRR 2JYYA 1AN1I 1FYBA 4B6DA 2NU1I 4UXJA 1N13A 1PTQA 1TOTA 3HH2C 1SGRI 3UGLA 2CJSC 2JW6A 3VDUA 2ERWA 1IY6A 5EX3A 4E1RA 3CXLA 1W4RA 2QQEA 4L9MA 3SGBI 5HI7A 1SGPI 2JA1A 2QQCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DS3 I;  1YTP A;  4GI3 C;  1MT1 A;  1Z7K B;  2N52 A;  3TJQ A;  1CGJ I;  2SGD I;  1UVG A;  1TGS I;  1H0Z A;  2XRC A;  1TBQ R;  4OVO A;  1KMA A;  1SGN I;  1CT0 I;  2GKT I;  1SGD I;  1PCE A;  2KMO A;  2NU4 I;  1CHO I;  2KMP A;  1SGE I;  2SGF I;  3OVO A;  2KMQ A;  1Y1C A;  1CGI I;  1LR8 A;  1BUS A;  2SGQ I;  1PJU A;  1CSO I;  1NUB A;  3SGQ I;  1CT2 I;  2V53 A;  2M5X A;  1UVF A;  1TUR A;  2NU0 I;  1LR7 A;  1OYV I;  1OMT A;  4HGU A;  2F3C I;  2NU2 I;  5DAE A;  1IY5 A;  1HJA I;  1OMU A;  2GKV A;  2ARP F;  1CT4 I;  3QTL D;  3B4V C;  1UUC A;  1IW4 A;  1M8B A;  2KMR A;  2N71 A;  1PPF I;  1SGQ I;  2SGE I;  1OVO A;  1TUS A;  2JZM A;  1LR9 A;  2GKR I;  1HDL A;  1BMO A;  1CE3 A;  2B0U C;  2BUS A;  2SGP I;  1YU6 C;  2P6A C;  1Y1B A;  1HPT A;  1TIH A;  2N17 A;  4SGB I;  1R0R I;  1M8C A;  3SEK C;  1DS2 I;  2NU3 I;  2WCY A;  2QQD A;  5JHW C;  2KCX A;  1SGY I;  2JXD A;  2LEO A;  1TBR R;  2JYY A;  1AN1 I;  1FYB A;  2NU1 I;  1N13 A;  3HH2 C;  1SGR I;  1IY6 A;  2ERW A;  3SGB I;  1SGP I;  2OVO A;  2QQC A; 
#chains in the Genus database with same CATH topology
 3UFF A;  2ENN A;  1DS3 I;  2OVO A;  1YTP A;  4GI3 C;  5FUX A;  3UEJ A;  2J87 A;  1MT1 A;  3MEK A;  1Z7K B;  3FSY A;  5E3Q A;  1TBO A;  2N52 A;  2VRW B;  3TJQ A;  1CGJ I;  2SGD I;  1UVG A;  1TGS I;  3PDN A;  1H0Z A;  2XRC A;  1TBQ R;  1V1H A;  3VE5 A;  5FUV A;  4JCV E;  4OVO A;  1XBT A;  1RFH A;  1KMA A;  1SGN I;  1CT0 I;  3E59 A;  7WGA A;  1X4S A;  2GKT I;  2J9R A;  1SGD I;  1P9Z A;  1PCE A;  1ULM A;  1X74 A;  2KMO A;  1XX6 A;  2E5R A;  3OXF A;  4DNC A;  2NU4 I;  1CHO I;  1NXU A;  2DKV A;  2KMP A;  1W3S A;  1SGE I;  2K9H A;  3VDP A;  2SGF I;  1FY7 A;  3OVO A;  2KMQ A;  1MJB A;  1Y1C A;  1CGI I;  1K7T A;  2QQ0 A;  2YUU A;  1LR8 A;  3R5D A;  2CWG A;  1BUS A;  3UGD A;  3UOE A;  4WP4 A;  2LB7 A;  2OZU A;  5HQ8 A;  5CCM A;  1Y8F A;  2SGQ I;  1PJU A;  2GVI A;  1UHA A;  1MJA A;  3E2I A;  1CSO I;  2V1C A;  1NUB A;  3SGQ I;  1CT2 I;  3TO7 A;  2ELI A;  1K7V A;  2M5X A;  2V53 A;  1R79 A;  1UVF A;  2X52 A;  3D00 A;  5FUY A;  1FAQ A;  1TUR A;  2NU0 I;  1LR7 A;  1PTR A;  4A24 A;  2GIV A;  2RIJ A;  2OD1 A;  1HEV A;  2OU2 A;  1OYV I;  1OMT A;  4HGU A;  1TBN A;  2F3C I;  2NU2 I;  1U5K A;  5DAE A;  1IY5 A;  1HJA I;  2PQ8 A;  1OMU A;  3OXL A;  2GKV A;  3OXG A;  3GOX A;  2ROW A;  4AML A;  2ARP F;  1CT4 I;  1Q9B A;  1KBE A;  1ULN A;  3BJI A;  3OL0 A;  3QTL D;  3RU0 A;  2A20 A;  3FC3 A;  2CWH A;  5EX0 A;  4FKD A;  3B4V C;  1WGT A;  1K7U A;  3QWP A;  3R5B A;  1UUC A;  3QAH A;  2YQP A;  5J8C A;  1WGC A;  1M8B A;  1IW4 A;  2KMR A;  2N71 A;  1PPF I;  1SGQ I;  2SGE I;  3R5C A;  2ENZ A;  3UGI A;  3KY9 A;  2RC4 A;  1MJ9 A;  1OVO A;  1VDD A;  2WGC A;  1TUS A;  2L8E A;  1ULK A;  2JZM A;  3TOB A;  5FUW A;  1LR9 A;  2GKR I;  2ORW A;  1HDL A;  1BMO A;  2LUY A;  3R5A A;  5CCL A;  2ORV A;  3TOA A;  1CE3 A;  2B0U C;  2BUS A;  2W0T A;  3TO9 A;  3UEY A;  2N1A B;  4UXH A;  2SGP I;  1YU6 C;  1WTJ A;  1Z2I A;  2B8T A;  1P9G A;  2P6A C;  1KBF A;  2ODD A;  1WKX A;  1Y1B A;  1HPT A;  1TIH A;  1V1I A;  2N17 A;  2E73 A;  2L7X A;  4SGB I;  2CWF A;  1R0R I;  1M8C A;  2QPO A;  3SEK C;  1FAR A;  1DS2 I;  2DB6 A;  4E1P A;  2NU3 I;  2WCY A;  2QQD A;  2V1C C;  5JHW C;  2DIP A;  2KCX A;  1SGY I;  2UZ3 A;  5E3R A;  9WGA A;  1XA6 A;  2JXD A;  2WVJ A;  2FNF X;  5J8F A;  3TO6 A;  2X3T A;  2LEO A;  4UXI A;  1TBR R;  2JYY A;  3FSX A;  4MPI A;  1AN1 I;  1FYB A;  4B6D A;  2NU1 I;  4UXJ A;  2Y0M A;  1N13 A;  1PTQ A;  1TOT A;  3HH2 C;  1S20 A;  1SGR I;  2CJS C;  2JW6 A;  3UGL A;  2ERW A;  3VDU A;  1IY6 A;  5EX3 A;  4E1R A;  3CXL A;  1W4R A;  2QQE A;  5E3P A;  4L9M A;  2UVO A;  3SGB I;  5HI7 A;  1SGP I;  2JA1 A;  2QQC A; 
#chains in the Genus database with same CATH homology
 3UFF A;  2ENN A;  1DS3 I;  2OVO A;  1YTP A;  4GI3 C;  5FUX A;  2J87 A;  1MT1 A;  3MEK A;  1Z7K B;  1TBO A;  2N52 A;  2VRW B;  3TJQ A;  1CGJ I;  2SGD I;  1UVG A;  1TGS I;  3PDN A;  1H0Z A;  2XRC A;  1TBQ R;  1V1H A;  3VE5 A;  5FUV A;  4JCV E;  4OVO A;  1XBT A;  1RFH A;  1KMA A;  1SGN I;  1CT0 I;  3E59 A;  1X4S A;  2GKT I;  2J9R A;  1SGD I;  1PCE A;  2KMO A;  1X74 A;  3OXF A;  3UEJ A;  1XX6 A;  2E5R A;  2NU4 I;  1CHO I;  2KMP A;  1W3S A;  1SGE I;  2K9H A;  3VDP A;  2SGF I;  3OVO A;  2KMQ A;  1Y1C A;  1CGI I;  2QQ0 A;  2YUU A;  1LR8 A;  1BUS A;  3UGD A;  5HQ8 A;  5CCM A;  1Y8F A;  2SGQ I;  1PJU A;  2GVI A;  3E2I A;  1CSO I;  2V1C A;  1NUB A;  3SGQ I;  1CT2 I;  2ELI A;  2V53 A;  2M5X A;  3D00 A;  1R79 A;  1UVF A;  5FUY A;  1FAQ A;  1TUR A;  2NU0 I;  1LR7 A;  1PTR A;  4A24 A;  2OD1 A;  1OYV I;  1OMT A;  4HGU A;  1TBN A;  2F3C I;  2NU2 I;  1U5K A;  5DAE A;  1IY5 A;  1HJA I;  1OMU A;  3OXL A;  2GKV A;  3OXG A;  3GOX A;  2ROW A;  2ARP F;  1CT4 I;  3BJI A;  1KBE A;  3OL0 A;  3RU0 A;  3QTL D;  3FC3 A;  2A20 A;  5EX0 A;  4FKD A;  3B4V C;  3QWP A;  1UUC A;  1IW4 A;  2YQP A;  1M8B A;  2KMR A;  2N71 A;  1PPF I;  1SGQ I;  2SGE I;  2ENZ A;  3UGI A;  3KY9 A;  1VDD A;  1OVO A;  1TUS A;  2L8E A;  2JZM A;  5FUW A;  1LR9 A;  2GKR I;  2ORW A;  1HDL A;  1BMO A;  2LUY A;  5CCL A;  2ORV A;  1CE3 A;  2B0U C;  2BUS A;  2W0T A;  3UEY A;  2N1A B;  4UXH A;  2SGP I;  1YU6 C;  2B8T A;  2P6A C;  1KBF A;  2ODD A;  1Y1B A;  1HPT A;  1TIH A;  1V1I A;  2N17 A;  2E73 A;  2L7X A;  4SGB I;  2QPO A;  1R0R I;  1M8C A;  3SEK C;  1FAR A;  1DS2 I;  2DB6 A;  4E1P A;  2NU3 I;  2WCY A;  2QQD A;  2V1C C;  5JHW C;  2DIP A;  2KCX A;  1SGY I;  2UZ3 A;  1XA6 A;  2JXD A;  2WVJ A;  2FNF X;  2LEO A;  4UXI A;  1TBR R;  2JYY A;  1AN1 I;  1FYB A;  4B6D A;  2NU1 I;  4UXJ A;  1N13 A;  1PTQ A;  1TOT A;  3HH2 C;  1SGR I;  3UGL A;  2CJS C;  2JW6 A;  3VDU A;  2ERW A;  1IY6 A;  5EX3 A;  4E1R A;  3CXL A;  1W4R A;  2QQE A;  4L9M A;  3SGB I;  5HI7 A;  1SGP I;  2JA1 A;  2QQC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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