2KMOA

Solution structure of native leech-derived tryptase inhibitor, ldti
Total Genus 6
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
44
structure length
44
Chain Sequence
KKVCACPKILKPVCGSDGRTYANSCIARCNGVSIKSEGSCPTGI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
pubmed doi rcsb
molecule tags Hydrolase
source organism Hirudo medicinalis
molecule keywords Leech-derived tryptase inhibitor C
total genus 6
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2009-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2kmoA00
1TURA 3TJQA 1N13A 2XRCA 1Z7KB 1CT0I 1R0RI 1LR8A 2JZMA 2NU0I 1SGNI 2GKRI 1LR7A 2SGPI 1OVOA 2BUSA 1NUBA 2SGEI 2KMRA 1H0ZA 2GKTI 4SGBI 1DS3I 2KMPA 1Y1CA 2KCXA 1IW4A 1UUCA 4GI3C 1TGSI 1AN1I 2ERWA 2ARPF 1M8BA 1YU6C 3SEKC 4OVOA 2NU1I 1MT1A 1UVGA 2F3CI 1CT4I 2WCYA 2GKVA 2OVOA 1SGQI 2SGFI 2KMOA 2M5XA 1PCEA 2NU3I 2LEOA 1TBQR 1IY6A 2KMQA 1IY5A 1Y1BA 1SGEI 5JHWC 1SGRI 1YTPA 1SGDI 2QQCA 1PJUA 1DS2I 1M8CA 1TUSA 1CE3A 1CSOI 3OVOA 1TBRR 1CHOI 1CGJI 2NU4I 2NU2I 2V53A 2N17A 2N52A 1HPTA 1PPFI 1UVFA 2SGQI 3QTLD 1OYVI 3B4VC 1HDLA 2QQDA 1CGII 1BUSA 2JYYA 2B0UC 5DAEA 2JXDA 1LR9A 1OMTA 2SGDI 1HJAI 2N71A 1FYBA 3SGBI 1CT2I 3HH2C 3SGQI 1OMUA 1BMOA 1SGYI 4HGUA 1SGPI 1TIHA 1KMAA 2P6AC
chains in the Genus database with same CATH superfamily
1TURA 3TJQA 2L7XA 1N13A 1PTQA 2XRCA 1Z7KB 3KY9A 5FUWA 5E3RA 1CT0I 5FUYA 3OXLA 1R0RI 2Y0MA 1LR8A 1UHAA 2A20A 2CWGA 1W3SA 1Y8FA 2ROWA 1WGTA 2JZMA 4E1RA 2NU0I 1SGNI 2ELIA 2GKRI 2K9HA 1LR7A 2SGPI 1OVOA 5FUXA 2BUSA 1NUBA 2SGEI 1MJAA 2QPOA 2KMRA 3R5DA 1H0ZA 3MEKA 2GKTI 4SGBI 1DS3I 2OU2A 1ULNA 2CJSC 5HI7A 5CCLA 2KMPA 1X74A 1Y1CA 2KCXA 1IW4A 1UUCA 2X3TA 1K7VA 3QAHA 4GI3C 1FARA 1TGSI 1AN1I 2ERWA 2ARPF 1M8BA 1YU6C 4MPIA 3E2IA 1X4SA 2QQ0A 1NXUA 1P9GA 5J8FA 3FSXA 3SEKC 4OVOA 3TO9A 3VDUA 2NU1I 4UXIA 1MT1A 5E3PA 5J8CA 1KBFA 2GVIA 4L9MA 1PTRA 1V1HA 5HQ8A 1MJ9A 1UVGA 3RU0A 2F3CI 1CT4I 1W4RA 2GKVA 2N1AB 1KBEA 2OVOA 2WCYA 1SGQI 3VE5A 2SGFI 2KMOA 2DKVA 3E59A 3R5CA 2M5XA 1PCEA 2L8EA 2NU3I 2LEOA 3VDPA 4DNCA 3TO6A 1TBQR 3TO7A 3OXGA 1IY6A 1Q9BA 4FKDA 2CWFA 3PDNA 2KMQA 1IY5A 1Y1BA 2OZUA 1HEVA 1SGEI 5JHWC 1SGRI 1YTPA 1SGDI 3OL0A 1TBOA 3TOBA 2X52A 2QQCA 2FNFX 4WP4A 1PJUA 1DS2I 1FY7A 3UOEA 1R79A 5EX3A 2B8TA 1MJBA 1Z2IA 1M8CA 1K7UA 1WKXA 1TUSA 2UZ3A 1CE3A 1CSOI 3OVOA 1TBRR 1CHOI 3UGLA 7WGAA 2ODDA 3FC3A 1CGJI 2ENZA 2NU4I 3BJIA 1V1IA 2ORVA 3CXLA 3UFFA 4B6DA 1HDLA 2E73A 9WGAA 1WGCA 2NU2I 2V53A 2ORWA 2N17A 2N52A 4A24A 1HPTA 1PPFI 1UVFA 1RFHA 3UGIA 2SGQI 2WVJA 3QTLD 1OYVI 2WGCA 4UXHA 3B4VC 4JCVE 2UVOA 5FUVA 1WTJA 2QQDA 1ULKA 1CGII 2E5RA 3UEYA 5CCMA 1BUSA 2JYYA 1XX6A 2B0UC 4AMLA 1XA6A 3FSYA 1TOTA 2LUYA 5DAEA 3GOXA 2RC4A 2QQEA 1ULMA 3QWPA 2JXDA 1P9ZA 2W0TA 1LR9A 3D00A 1OMTA 4UXJA 2J87A 2DB6A 2CWHA 2SGDI 2GIVA 1HJAI 2N71A 1FYBA 2LB7A 2RIJA 3R5AA 3UEJA 4E1PA 3SGBI 2DIPA 2ENNA 1CT2I 2YUUA 3R5BA 3UGDA 3HH2C 3SGQI 2PQ8A 2V1CC 2VRWB 5EX0A 1OMUA 2YQPA 3TOAA 2OD1A 1BMOA 2JA1A 3OXFA 1SGYI 1FAQA 1XBTA 1VDDA 5E3QA 4HGUA 2JW6A 1SGPI 1TIHA 1U5KA 1KMAA 1TBNA 2P6AC 1K7TA 2J9RA 1S20A 2V1CA
chains in the Genus database with same CATH topology
1TURA 3TJQA 2L7XA 1N13A 1PTQA 2XRCA 1Z7KB 3KY9A 5FUWA 5FUYA 1CT0I 3OXLA 1R0RI 1LR8A 2A20A 1W3SA 1Y8FA 2ROWA 2JZMA 4E1RA 2NU0I 1SGNI 2ELIA 2GKRI 2K9HA 1LR7A 2SGPI 1OVOA 5FUXA 2BUSA 1NUBA 2SGEI 2QPOA 2KMRA 1H0ZA 3MEKA 2GKTI 4SGBI 1DS3I 5CCLA 2CJSC 5HI7A 2KMPA 1X74A 1Y1CA 2KCXA 1IW4A 1UUCA 4GI3C 1FARA 1TGSI 1AN1I 2ERWA 2ARPF 1M8BA 1YU6C 3E2IA 1X4SA 2QQ0A 3SEKC 3VDUA 4OVOA 2NU1I 4UXIA 1MT1A 1KBFA 2GVIA 4L9MA 1PTRA 1V1HA 5HQ8A 1UVGA 3RU0A 2F3CI 1CT4I 1W4RA 2GKVA 2N1AB 1KBEA 2OVOA 2WCYA 1SGQI 3VE5A 2SGFI 2KMOA 3E59A 2M5XA 1PCEA 2L8EA 2NU3I 2LEOA 3VDPA 1TBQR 3OXGA 1IY6A 4FKDA 3PDNA 2KMQA 1IY5A 1Y1BA 1SGEI 5JHWC 1YTPA 1SGRI 1SGDI 3OL0A 1TBOA 2QQCA 2FNFX 1PJUA 1DS2I 1R79A 5EX3A 2B8TA 1M8CA 2UZ3A 1TUSA 1CE3A 1CSOI 3OVOA 1TBRR 1CHOI 3UGLA 2ODDA 3FC3A 1CGJI 2ENZA 2NU4I 3BJIA 1V1IA 2ORVA 3CXLA 3UFFA 4B6DA 2E73A 2NU2I 2V53A 2ORWA 2N17A 2N52A 4A24A 1HPTA 1PPFI 1UVFA 1RFHA 3UGIA 2SGQI 2WVJA 3QTLD 1OYVI 4UXHA 3B4VC 4JCVE 5FUVA 3UEYA 2QQDA 5CCMA 1CGII 2E5RA 1HDLA 1BUSA 2JYYA 1XX6A 2B0UC 1XA6A 1TOTA 2LUYA 5DAEA 3GOXA 2QQEA 3QWPA 2JXDA 2W0TA 1LR9A 3D00A 1OMTA 4UXJA 2J87A 2DB6A 2SGDI 1HJAI 2N71A 1FYBA 3UEJA 4E1PA 3SGBI 2DIPA 2ENNA 1CT2I 2YUUA 3UGDA 3HH2C 3SGQI 2VRWB 2V1CC 5EX0A 1OMUA 2YQPA 2OD1A 1BMOA 2JA1A 3OXFA 1SGYI 1FAQA 1XBTA 1VDDA 4HGUA 2JW6A 1SGPI 1TIHA 1U5KA 1KMAA 1TBNA 2P6AC 2J9RA 2V1CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TUR A;  3TJQ A;  1N13 A;  2XRC A;  1Z7K B;  1CT0 I;  1R0R I;  1LR8 A;  2JZM A;  2NU0 I;  1SGN I;  2GKR I;  1LR7 A;  2SGP I;  1OVO A;  2BUS A;  1NUB A;  2SGE I;  2KMR A;  1H0Z A;  2GKT I;  4SGB I;  1DS3 I;  2KMP A;  1Y1C A;  2KCX A;  1IW4 A;  1UUC A;  4GI3 C;  1TGS I;  1AN1 I;  2ERW A;  2ARP F;  1M8B A;  1YU6 C;  3SEK C;  4OVO A;  2NU1 I;  1MT1 A;  1UVG A;  2F3C I;  1CT4 I;  2WCY A;  2GKV A;  2OVO A;  1SGQ I;  2SGF I;  2KMO A;  2M5X A;  1PCE A;  2NU3 I;  2LEO A;  1TBQ R;  1IY6 A;  2KMQ A;  1IY5 A;  1Y1B A;  1SGE I;  5JHW C;  1SGR I;  1YTP A;  1SGD I;  2QQC A;  1PJU A;  1DS2 I;  1M8C A;  1TUS A;  1CE3 A;  1CSO I;  3OVO A;  1TBR R;  1CHO I;  1CGJ I;  2NU4 I;  2NU2 I;  2V53 A;  2N17 A;  2N52 A;  1HPT A;  1PPF I;  1UVF A;  2SGQ I;  3QTL D;  1OYV I;  3B4V C;  1HDL A;  2QQD A;  1CGI I;  1BUS A;  2JYY A;  2B0U C;  5DAE A;  2JXD A;  1LR9 A;  1OMT A;  2SGD I;  1HJA I;  2N71 A;  1FYB A;  3SGB I;  1CT2 I;  3HH2 C;  3SGQ I;  1OMU A;  1BMO A;  1SGY I;  4HGU A;  1SGP I;  1TIH A;  1KMA A;  2P6A C; 
#chains in the Genus database with same CATH topology
 1TUR A;  3TJQ A;  2L7X A;  1N13 A;  1PTQ A;  2XRC A;  1Z7K B;  3KY9 A;  5FUW A;  5E3R A;  1CT0 I;  5FUY A;  3OXL A;  1R0R I;  2Y0M A;  1LR8 A;  1UHA A;  2A20 A;  2CWG A;  1W3S A;  1Y8F A;  2ROW A;  1WGT A;  2JZM A;  4E1R A;  2NU0 I;  1SGN I;  2ELI A;  2GKR I;  2K9H A;  1LR7 A;  2SGP I;  1OVO A;  5FUX A;  2BUS A;  1NUB A;  2SGE I;  1MJA A;  2QPO A;  2KMR A;  3R5D A;  1H0Z A;  3MEK A;  2GKT I;  4SGB I;  1DS3 I;  2OU2 A;  1ULN A;  2CJS C;  5HI7 A;  5CCL A;  2KMP A;  1X74 A;  1Y1C A;  2KCX A;  1IW4 A;  1UUC A;  2X3T A;  1K7V A;  3QAH A;  4GI3 C;  1FAR A;  1TGS I;  1AN1 I;  2ERW A;  2ARP F;  1M8B A;  1YU6 C;  4MPI A;  3E2I A;  1X4S A;  2QQ0 A;  1NXU A;  1P9G A;  5J8F A;  3FSX A;  3SEK C;  4OVO A;  3TO9 A;  3VDU A;  2NU1 I;  4UXI A;  1MT1 A;  5E3P A;  5J8C A;  1KBF A;  2GVI A;  4L9M A;  1PTR A;  1V1H A;  5HQ8 A;  1MJ9 A;  1UVG A;  3RU0 A;  2F3C I;  1CT4 I;  1W4R A;  2GKV A;  2N1A B;  1KBE A;  2OVO A;  2WCY A;  1SGQ I;  3VE5 A;  2SGF I;  2KMO A;  2DKV A;  3E59 A;  3R5C A;  2M5X A;  1PCE A;  2L8E A;  2NU3 I;  2LEO A;  3VDP A;  4DNC A;  3TO6 A;  1TBQ R;  3TO7 A;  3OXG A;  1IY6 A;  1Q9B A;  4FKD A;  2CWF A;  3PDN A;  2KMQ A;  1IY5 A;  1Y1B A;  2OZU A;  1HEV A;  1SGE I;  5JHW C;  1SGR I;  1YTP A;  1SGD I;  3OL0 A;  1TBO A;  3TOB A;  2X52 A;  2QQC A;  2FNF X;  4WP4 A;  1PJU A;  1DS2 I;  1FY7 A;  3UOE A;  1R79 A;  5EX3 A;  2B8T A;  1MJB A;  1Z2I A;  1M8C A;  1K7U A;  1WKX A;  1TUS A;  2UZ3 A;  1CE3 A;  1CSO I;  3OVO A;  1TBR R;  1CHO I;  3UGL A;  7WGA A;  2ODD A;  3FC3 A;  1CGJ I;  2ENZ A;  2NU4 I;  3BJI A;  1V1I A;  2ORV A;  3CXL A;  3UFF A;  4B6D A;  1HDL A;  2E73 A;  9WGA A;  1WGC A;  2NU2 I;  2V53 A;  2ORW A;  2N17 A;  2N52 A;  4A24 A;  1HPT A;  1PPF I;  1UVF A;  1RFH A;  3UGI A;  2SGQ I;  2WVJ A;  3QTL D;  1OYV I;  2WGC A;  4UXH A;  3B4V C;  4JCV E;  2UVO A;  5FUV A;  1WTJ A;  2QQD A;  1ULK A;  1CGI I;  2E5R A;  3UEY A;  5CCM A;  1BUS A;  2JYY A;  1XX6 A;  2B0U C;  4AML A;  1XA6 A;  3FSY A;  1TOT A;  2LUY A;  5DAE A;  3GOX A;  2RC4 A;  2QQE A;  1ULM A;  3QWP A;  2JXD A;  1P9Z A;  2W0T A;  1LR9 A;  3D00 A;  1OMT A;  4UXJ A;  2J87 A;  2DB6 A;  2CWH A;  2SGD I;  2GIV A;  1HJA I;  2N71 A;  1FYB A;  2LB7 A;  2RIJ A;  3R5A A;  3UEJ A;  4E1P A;  3SGB I;  2DIP A;  2ENN A;  1CT2 I;  2YUU A;  3R5B A;  3UGD A;  3HH2 C;  3SGQ I;  2PQ8 A;  2V1C C;  2VRW B;  5EX0 A;  1OMU A;  2YQP A;  3TOA A;  2OD1 A;  1BMO A;  2JA1 A;  3OXF A;  1SGY I;  1FAQ A;  1XBT A;  1VDD A;  5E3Q A;  4HGU A;  2JW6 A;  1SGP I;  1TIH A;  1U5K A;  1KMA A;  1TBN A;  2P6A C;  1K7T A;  2J9R A;  1S20 A;  2V1C A; 
#chains in the Genus database with same CATH homology
 1TUR A;  3TJQ A;  2L7X A;  1N13 A;  1PTQ A;  2XRC A;  1Z7K B;  3KY9 A;  5FUW A;  5FUY A;  1CT0 I;  3OXL A;  1R0R I;  1LR8 A;  2A20 A;  1W3S A;  1Y8F A;  2ROW A;  2JZM A;  4E1R A;  2NU0 I;  1SGN I;  2ELI A;  2GKR I;  2K9H A;  1LR7 A;  2SGP I;  1OVO A;  5FUX A;  2BUS A;  1NUB A;  2SGE I;  2QPO A;  2KMR A;  1H0Z A;  3MEK A;  2GKT I;  4SGB I;  1DS3 I;  5CCL A;  2CJS C;  5HI7 A;  2KMP A;  1X74 A;  1Y1C A;  2KCX A;  1IW4 A;  1UUC A;  4GI3 C;  1FAR A;  1TGS I;  1AN1 I;  2ERW A;  2ARP F;  1M8B A;  1YU6 C;  3E2I A;  1X4S A;  2QQ0 A;  3SEK C;  3VDU A;  4OVO A;  2NU1 I;  4UXI A;  1MT1 A;  1KBF A;  2GVI A;  4L9M A;  1PTR A;  1V1H A;  5HQ8 A;  1UVG A;  3RU0 A;  2F3C I;  1CT4 I;  1W4R A;  2GKV A;  2N1A B;  1KBE A;  2OVO A;  2WCY A;  1SGQ I;  3VE5 A;  2SGF I;  2KMO A;  3E59 A;  2M5X A;  1PCE A;  2L8E A;  2NU3 I;  2LEO A;  3VDP A;  1TBQ R;  3OXG A;  1IY6 A;  4FKD A;  3PDN A;  2KMQ A;  1IY5 A;  1Y1B A;  1SGE I;  5JHW C;  1YTP A;  1SGR I;  1SGD I;  3OL0 A;  1TBO A;  2QQC A;  2FNF X;  1PJU A;  1DS2 I;  1R79 A;  5EX3 A;  2B8T A;  1M8C A;  2UZ3 A;  1TUS A;  1CE3 A;  1CSO I;  3OVO A;  1TBR R;  1CHO I;  3UGL A;  2ODD A;  3FC3 A;  1CGJ I;  2ENZ A;  2NU4 I;  3BJI A;  1V1I A;  2ORV A;  3CXL A;  3UFF A;  4B6D A;  2E73 A;  2NU2 I;  2V53 A;  2ORW A;  2N17 A;  2N52 A;  4A24 A;  1HPT A;  1PPF I;  1UVF A;  1RFH A;  3UGI A;  2SGQ I;  2WVJ A;  3QTL D;  1OYV I;  4UXH A;  3B4V C;  4JCV E;  5FUV A;  3UEY A;  2QQD A;  5CCM A;  1CGI I;  2E5R A;  1HDL A;  1BUS A;  2JYY A;  1XX6 A;  2B0U C;  1XA6 A;  1TOT A;  2LUY A;  5DAE A;  3GOX A;  2QQE A;  3QWP A;  2JXD A;  2W0T A;  1LR9 A;  3D00 A;  1OMT A;  4UXJ A;  2J87 A;  2DB6 A;  2SGD I;  1HJA I;  2N71 A;  1FYB A;  3UEJ A;  4E1P A;  3SGB I;  2DIP A;  2ENN A;  1CT2 I;  2YUU A;  3UGD A;  3HH2 C;  3SGQ I;  2VRW B;  2V1C C;  5EX0 A;  1OMU A;  2YQP A;  2OD1 A;  1BMO A;  2JA1 A;  3OXF A;  1SGY I;  1FAQ A;  1XBT A;  1VDD A;  4HGU A;  2JW6 A;  1SGP I;  1TIH A;  1U5K A;  1KMA A;  1TBN A;  2P6A C;  2J9R A;  2V1C A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...