2L8EA

Solution nmr structure of fcs domain of human polyhomeotic homolog 1 (hph1)
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
49
structure length
49
Chain Sequence
GTRGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title 1H, 15N and 13C assigned chemical shifts of FCS domain from human polyhomeotic homolog 1
rcsb
molecule tags Dna binding protein
source organism Homo sapiens
molecule keywords Polyhomeotic-like protein 1
total genus 9
structure length 49
sequence length 49
ec nomenclature
pdb deposition date 2011-01-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.160 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2l8eA00
2W0TA 2L8EA
chains in the Genus database with same CATH superfamily
2JZMA 1OYVI 2CWHA 1SGPI 1PPFI 1WGCA 1Z2IA 3OXGA 3SEKC 1DS3I 2NU0I 1PJUA 1TIHA 2OD1A 2RC4A 1IY5A 5HI7A 1NXUA 4DNCA 4FKDA 2CWGA 3R5AA 2GKRI 1V1IA 2KMRA 2GKVA 1R0RI 2ODDA 9WGAA 3TO6A 2N17A 1XA6A 1FARA 1MJBA 1WTJA 3TO9A 1OMUA 5HQ8A 1N13A 1X4SA 1CSOI 2GKTI 3UGDA 1KMAA 3UEJA 2DB6A 3MEKA 2ORVA 3E59A 3PDNA 1M8CA 3CXLA 5FUXA 4AMLA 2ERWA 1LR9A 3R5BA 2F3CI 1LR8A 3HH2C 3VDPA 2L8EA 2N71A 2SGPI 2ENNA 1PTRA 2KMPA 2ORWA 2B0UC 2QQCA 2WVJA 1WGTA 1NUBA 1UVGA 3QAHA 1DS2I 2ARPF 1OMTA 1CGJI 2SGEI 1LR7A 2UZ3A 4E1PA 1BMOA 1OVOA 1MJAA 5FUWA 5E3RA 1SGNI 2L7XA 2OZUA 2SGQI 3OXLA 5E3PA 1UUCA 4UXIA 1HDLA 1WKXA 1YTPA 1FAQA 1HEVA 2JW6A 2RIJA 3KY9A 3FC3A 1TUSA 2NU3I 5CCLA 2E73A 2J87A 1Y1CA 4L9MA 5CCMA 2JXDA 2V1CA 1X74A 3TOAA 3FSYA 4GI3C 3D00A 3UGLA 2DIPA 1MT1A 1HPTA 3UOEA 1TBQR 1CHOI 1YU6C 1FYBA 3BJIA 1S20A 1FY7A 1SGYI 2ENZA 1PTQA 3GOXA 4MPIA 2Y0MA 1TURA 1Q9BA 5JHWC 1Y1BA 1SGQI 2NU4I 2ROWA 2YUUA 3TJQA 1AN1I 1W3SA 2LUYA 1V1HA 5EX3A 3SGBI 7WGAA 1VDDA 1SGDI 2B8TA 1TBRR 2DKVA 2P6AC 3B4VC 1Z7KB 2N1AB 1MJ9A 1SGRI 1Y8FA 2LEOA 3UEYA 4WP4A 3VDUA 3TO7A 1H0ZA 2X52A 2V53A 1W4RA 3R5CA 1TOTA 2SGFI 1BUSA 2X3TA 1HJAI 1KBEA 1CT4I 1XBTA 2E5RA 1TGSI 2QQEA 1P9ZA 2QQ0A 2CWFA 2KMOA 1IW4A 4SGBI 5FUYA 3SGQI 2BUSA 2OVOA 1IY6A 2VRWB 1ULMA 1ULKA 1SGEI 2M5XA 2OU2A 2WCYA 1TBOA 1CT0I 1K7VA 3UGIA 5J8CA 3OXFA 3TOBA 2FNFX 2UVOA 2QPOA 2QQDA 4UXHA 4A24A 1M8BA 3QTLD 3FSXA 3OL0A 5EX0A 2K9HA 1PCEA 4JCVE 1P9GA 2LB7A 1TBNA 4UXJA 3QWPA 1CT2I 2J9RA 2JA1A 2GIVA 1K7UA 2A20A 3OVOA 2V1CC 3R5DA 1R79A 1U5KA 1KBFA 2KMQA 2W0TA 1K7TA 1UHAA 2JYYA 2NU2I 2YQPA 2CJSC 2XRCA 4HGUA 2ELIA 5DAEA 3UFFA 1ULNA 1UVFA 2N52A 2NU1I 4OVOA 3VE5A 2KCXA 2WGCA 5E3QA 5FUVA 1RFHA 3RU0A 2PQ8A 1CE3A 2GVIA 5J8FA 3E2IA 1CGII 4E1RA 1XX6A 2SGDI 4B6DA
chains in the Genus database with same CATH topology
2JZMA 1OYVI 3SEKC 1SGPI 1PPFI 3OXGA 1DS3I 2NU0I 1PJUA 1TIHA 2OD1A 1IY5A 5HI7A 4FKDA 2GKRI 1V1IA 2KMRA 2GKVA 1R0RI 2ODDA 2N17A 1XA6A 1FARA 1OMUA 5HQ8A 1N13A 1X4SA 1CSOI 2GKTI 3UGDA 1KMAA 3UEJA 2DB6A 3MEKA 2ORVA 3E59A 3PDNA 1M8CA 3CXLA 5FUXA 2ERWA 1LR9A 2F3CI 1LR8A 3HH2C 3VDPA 2L8EA 2N71A 2SGPI 2ENNA 1PTRA 2KMPA 2ORWA 2B0UC 2QQCA 2WVJA 1NUBA 1UVGA 1DS2I 2ARPF 1OMTA 1CGJI 2SGEI 1LR7A 2UZ3A 4E1PA 1BMOA 1OVOA 5FUWA 1SGNI 2L7XA 2SGQI 3OXLA 1UUCA 4UXIA 1HDLA 1YTPA 1FAQA 2JW6A 3KY9A 3FC3A 1TUSA 2NU3I 5CCLA 2E73A 2J87A 1Y1CA 4L9MA 5CCMA 2JXDA 2V1CA 1X74A 4GI3C 3D00A 3UGLA 2DIPA 1MT1A 1HPTA 1TBQR 1YU6C 1CHOI 1FYBA 3BJIA 1SGYI 2ENZA 3GOXA 1PTQA 1TURA 5JHWC 1Y1BA 1SGQI 2NU4I 2ROWA 2YUUA 3TJQA 1AN1I 1W3SA 2LUYA 1V1HA 5EX3A 3SGBI 1VDDA 1SGDI 2B8TA 1TBRR 2P6AC 3B4VC 1Z7KB 2N1AB 1SGRI 1Y8FA 2LEOA 3UEYA 3VDUA 1H0ZA 2V53A 1W4RA 1TOTA 2SGFI 1BUSA 1HJAI 1KBEA 1CT4I 1XBTA 2E5RA 1TGSI 2QQEA 2QQ0A 2KMOA 1IW4A 4SGBI 5FUYA 3SGQI 2BUSA 2OVOA 1IY6A 2VRWB 1SGEI 2M5XA 2WCYA 1TBOA 1CT0I 3UGIA 3OXFA 2FNFX 4UXHA 2QPOA 2QQDA 4A24A 1M8BA 3QTLD 3OL0A 5EX0A 2K9HA 1PCEA 4JCVE 1TBNA 4UXJA 3QWPA 1CT2I 2J9RA 2JA1A 2A20A 3OVOA 2V1CC 1R79A 1U5KA 1KBFA 2KMQA 2W0TA 2JYYA 2NU2I 2YQPA 2CJSC 2XRCA 4HGUA 2ELIA 5DAEA 3UFFA 1UVFA 2N52A 2NU1I 4OVOA 3VE5A 2KCXA 5FUVA 3RU0A 1RFHA 1CE3A 2GVIA 3E2IA 1CGII 4E1RA 1XX6A 2SGDI 4B6DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W0T A;  2L8E A; 
#chains in the Genus database with same CATH topology
 2JZM A;  1OYV I;  2CWH A;  1SGP I;  1PPF I;  1WGC A;  1Z2I A;  3OXG A;  3SEK C;  1DS3 I;  2NU0 I;  1PJU A;  1TIH A;  2OD1 A;  2RC4 A;  1IY5 A;  5HI7 A;  1NXU A;  4DNC A;  4FKD A;  2CWG A;  3R5A A;  2GKR I;  1V1I A;  2KMR A;  2GKV A;  1R0R I;  2ODD A;  9WGA A;  3TO6 A;  2N17 A;  1XA6 A;  1FAR A;  1MJB A;  1WTJ A;  3TO9 A;  1OMU A;  5HQ8 A;  1N13 A;  1X4S A;  1CSO I;  2GKT I;  3UGD A;  1KMA A;  3UEJ A;  2DB6 A;  3MEK A;  2ORV A;  3E59 A;  3PDN A;  1M8C A;  3CXL A;  5FUX A;  4AML A;  2ERW A;  1LR9 A;  3R5B A;  2F3C I;  1LR8 A;  3HH2 C;  3VDP A;  2L8E A;  2N71 A;  2SGP I;  2ENN A;  1PTR A;  2KMP A;  2ORW A;  2B0U C;  2QQC A;  2WVJ A;  1WGT A;  1NUB A;  1UVG A;  3QAH A;  1DS2 I;  2ARP F;  1OMT A;  1CGJ I;  2SGE I;  1LR7 A;  2UZ3 A;  4E1P A;  1BMO A;  1OVO A;  1MJA A;  5FUW A;  5E3R A;  1SGN I;  2L7X A;  2OZU A;  2SGQ I;  3OXL A;  5E3P A;  1UUC A;  4UXI A;  1HDL A;  1WKX A;  1YTP A;  1FAQ A;  1HEV A;  2JW6 A;  2RIJ A;  3KY9 A;  3FC3 A;  1TUS A;  2NU3 I;  5CCL A;  2E73 A;  2J87 A;  1Y1C A;  4L9M A;  5CCM A;  2JXD A;  2V1C A;  1X74 A;  3TOA A;  3FSY A;  4GI3 C;  3D00 A;  3UGL A;  2DIP A;  1MT1 A;  1HPT A;  3UOE A;  1TBQ R;  1CHO I;  1YU6 C;  1FYB A;  3BJI A;  1S20 A;  1FY7 A;  1SGY I;  2ENZ A;  1PTQ A;  3GOX A;  4MPI A;  2Y0M A;  1TUR A;  1Q9B A;  5JHW C;  1Y1B A;  1SGQ I;  2NU4 I;  2ROW A;  2YUU A;  3TJQ A;  1AN1 I;  1W3S A;  2LUY A;  1V1H A;  5EX3 A;  3SGB I;  7WGA A;  1VDD A;  1SGD I;  2B8T A;  1TBR R;  2DKV A;  2P6A C;  3B4V C;  1Z7K B;  2N1A B;  1MJ9 A;  1SGR I;  1Y8F A;  2LEO A;  3UEY A;  4WP4 A;  3VDU A;  3TO7 A;  1H0Z A;  2X52 A;  2V53 A;  1W4R A;  3R5C A;  1TOT A;  2SGF I;  1BUS A;  2X3T A;  1HJA I;  1KBE A;  1CT4 I;  1XBT A;  2E5R A;  1TGS I;  2QQE A;  1P9Z A;  2QQ0 A;  2CWF A;  2KMO A;  1IW4 A;  4SGB I;  5FUY A;  3SGQ I;  2BUS A;  2OVO A;  1IY6 A;  2VRW B;  1ULM A;  1ULK A;  1SGE I;  2M5X A;  2OU2 A;  2WCY A;  1TBO A;  1CT0 I;  1K7V A;  3UGI A;  5J8C A;  3OXF A;  3TOB A;  2FNF X;  2UVO A;  2QPO A;  2QQD A;  4UXH A;  4A24 A;  1M8B A;  3QTL D;  3FSX A;  3OL0 A;  5EX0 A;  2K9H A;  1PCE A;  4JCV E;  1P9G A;  2LB7 A;  1TBN A;  4UXJ A;  3QWP A;  1CT2 I;  2J9R A;  2JA1 A;  2GIV A;  1K7U A;  2A20 A;  3OVO A;  2V1C C;  3R5D A;  1R79 A;  1U5K A;  1KBF A;  2KMQ A;  2W0T A;  1K7T A;  1UHA A;  2JYY A;  2NU2 I;  2YQP A;  2CJS C;  2XRC A;  4HGU A;  2ELI A;  5DAE A;  3UFF A;  1ULN A;  1UVF A;  2N52 A;  2NU1 I;  4OVO A;  3VE5 A;  2KCX A;  2WGC A;  5E3Q A;  5FUV A;  1RFH A;  3RU0 A;  2PQ8 A;  1CE3 A;  2GVI A;  5J8F A;  3E2I A;  1CGI I;  4E1R A;  1XX6 A;  2SGD I;  4B6D A; 
#chains in the Genus database with same CATH homology
 2JZM A;  1OYV I;  3SEK C;  1SGP I;  1PPF I;  3OXG A;  1DS3 I;  2NU0 I;  1PJU A;  1TIH A;  2OD1 A;  1IY5 A;  5HI7 A;  4FKD A;  2GKR I;  1V1I A;  2KMR A;  2GKV A;  1R0R I;  2ODD A;  2N17 A;  1XA6 A;  1FAR A;  1OMU A;  5HQ8 A;  1N13 A;  1X4S A;  1CSO I;  2GKT I;  3UGD A;  1KMA A;  3UEJ A;  2DB6 A;  3MEK A;  2ORV A;  3E59 A;  3PDN A;  1M8C A;  3CXL A;  5FUX A;  2ERW A;  1LR9 A;  2F3C I;  1LR8 A;  3HH2 C;  3VDP A;  2L8E A;  2N71 A;  2SGP I;  2ENN A;  1PTR A;  2KMP A;  2ORW A;  2B0U C;  2QQC A;  2WVJ A;  1NUB A;  1UVG A;  1DS2 I;  2ARP F;  1OMT A;  1CGJ I;  2SGE I;  1LR7 A;  2UZ3 A;  4E1P A;  1BMO A;  1OVO A;  5FUW A;  1SGN I;  2L7X A;  2SGQ I;  3OXL A;  1UUC A;  4UXI A;  1HDL A;  1YTP A;  1FAQ A;  2JW6 A;  3KY9 A;  3FC3 A;  1TUS A;  2NU3 I;  5CCL A;  2E73 A;  2J87 A;  1Y1C A;  4L9M A;  5CCM A;  2JXD A;  2V1C A;  1X74 A;  4GI3 C;  3D00 A;  3UGL A;  2DIP A;  1MT1 A;  1HPT A;  1TBQ R;  1YU6 C;  1CHO I;  1FYB A;  3BJI A;  1SGY I;  2ENZ A;  3GOX A;  1PTQ A;  1TUR A;  5JHW C;  1Y1B A;  1SGQ I;  2NU4 I;  2ROW A;  2YUU A;  3TJQ A;  1AN1 I;  1W3S A;  2LUY A;  1V1H A;  5EX3 A;  3SGB I;  1VDD A;  1SGD I;  2B8T A;  1TBR R;  2P6A C;  3B4V C;  1Z7K B;  2N1A B;  1SGR I;  1Y8F A;  2LEO A;  3UEY A;  3VDU A;  1H0Z A;  2V53 A;  1W4R A;  1TOT A;  2SGF I;  1BUS A;  1HJA I;  1KBE A;  1CT4 I;  1XBT A;  2E5R A;  1TGS I;  2QQE A;  2QQ0 A;  2KMO A;  1IW4 A;  4SGB I;  5FUY A;  3SGQ I;  2BUS A;  2OVO A;  1IY6 A;  2VRW B;  1SGE I;  2M5X A;  2WCY A;  1TBO A;  1CT0 I;  3UGI A;  3OXF A;  2FNF X;  4UXH A;  2QPO A;  2QQD A;  4A24 A;  1M8B A;  3QTL D;  3OL0 A;  5EX0 A;  2K9H A;  1PCE A;  4JCV E;  1TBN A;  4UXJ A;  3QWP A;  1CT2 I;  2J9R A;  2JA1 A;  2A20 A;  3OVO A;  2V1C C;  1R79 A;  1U5K A;  1KBF A;  2KMQ A;  2W0T A;  2JYY A;  2NU2 I;  2YQP A;  2CJS C;  2XRC A;  4HGU A;  2ELI A;  5DAE A;  3UFF A;  1UVF A;  2N52 A;  2NU1 I;  4OVO A;  3VE5 A;  2KCX A;  5FUV A;  3RU0 A;  1RFH A;  1CE3 A;  2GVI A;  3E2I A;  1CGI I;  4E1R A;  1XX6 A;  2SGD I;  4B6D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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