2LEOA

Solution structure of esophageal cancer-related gene 2
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
66
structure length
66
Chain Sequence
SEAASLSPKKVDCSIYKKYPVVAIPCPITYLPVCGSDYITYGNECHLCTESLKSNGRVQFLHDGSC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NMR structure note: human esophageal cancer-related gene 2
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Homo sapiens
molecule keywords Serine protease inhibitor Kazal-type 7
total genus 14
structure length 66
sequence length 66
ec nomenclature
pdb deposition date 2011-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2leoA00
1TGSI 2QQCA 1HPTA 1IY5A 1OVOA 2KMRA 1PJUA 1SGPI 3TJQA 2SGEI 2M5XA 2KCXA 1YU6C 1TUSA 2LEOA 2NU1I 1CGJI 2P6AC 2JXDA 2KMPA 5DAEA 1CE3A 1SGDI 3QTLD 2GKTI 1SGQI 1CGII 2KMQA 1OMUA 2N17A 2WCYA 1DS2I 1PCEA 1Z7KB 1TBQR 1KMAA 2XRCA 3SGBI 2SGQI 1YTPA 1UVFA 3SEKC 2NU4I 1SGYI 3OVOA 2ARPF 2N71A 1M8CA 1CT0I 1NUBA 1TBRR 2V53A 1DS3I 2OVOA 4OVOA 2NU2I 1R0RI 1HDLA 1Y1CA 2SGFI 1LR8A 1AN1I 2NU0I 1SGNI 2KMOA 2QQDA 4HGUA 1UVGA 3SGQI 1IY6A 3HH2C 2GKRI 3B4VC 1H0ZA 1BMOA 1M8BA 1LR9A 1OMTA 1BUSA 2GKVA 1OYVI 4GI3C 1Y1BA 1CHOI 1TURA 2NU3I 2F3CI 5JHWC 2B0UC 2SGPI 2SGDI 2JZMA 2JYYA 1SGEI 1IW4A 1N13A 1LR7A 1UUCA 1PPFI 1SGRI 1CT4I 4SGBI 2ERWA 1CSOI 1MT1A 1TIHA 1HJAI 1CT2I 1FYBA 2BUSA 2N52A
chains in the Genus database with same CATH superfamily
1TGSI 1V1IA 2UVOA 1MJBA 3VDUA 2K9HA 2QQCA 2FNFX 1HPTA 3UOEA 1TBNA 1Y8FA 1IY5A 1ULKA 1OVOA 2KMRA 1PJUA 1SGPI 2RIJA 3TJQA 2SGEI 2M5XA 2KCXA 5EX0A 1YU6C 3KY9A 1TUSA 3UEJA 2LEOA 2NU1I 2WVJA 2Y0MA 3BJIA 4JCVE 2CWFA 2OD1A 4L9MA 1CGJI 2P6AC 5FUVA 3R5BA 1X74A 1KBEA 2LUYA 2V1CC 2ENNA 2JXDA 2KMPA 5DAEA 2VRWB 3TO7A 3TO9A 3RU0A 1VDDA 1HEVA 3QAHA 1CE3A 5FUXA 1SGDI 3QTLD 2GKTI 2L8EA 1WTJA 3UGDA 1SGQI 1CGII 1PTRA 2KMQA 3OXFA 1Q9BA 2GVIA 3VE5A 3E2IA 1OMUA 5J8CA 2ENZA 1RFHA 2N17A 2WCYA 1DS2I 1PCEA 1W4RA 2YQPA 1KBFA 1Z7KB 1TBQR 3D00A 1KMAA 2OZUA 3TO6A 2XRCA 2QQ0A 3SGBI 3TOBA 3VDPA 1XA6A 2SGQI 1YTPA 2JW6A 3TOAA 2DB6A 1UVFA 2E73A 2QQEA 5CCMA 2ORVA 2NU4I 3SEKC 1SGYI 5FUWA 4FKDA 2OU2A 5HI7A 3UEYA 9WGAA 3OVOA 2ARPF 2J87A 3E59A 2N71A 2B8TA 1M8CA 1CT0I 1NUBA 1TBRR 1ULNA 1Z2IA 2V53A 1DS3I 2OVOA 4OVOA 2NU2I 2X52A 2L7XA 2RC4A 1R0RI 3CXLA 3UGIA 1Y1CA 1HDLA 2SGFI 3OXGA 3GOXA 4WP4A 3FC3A 1LR8A 1MJAA 4UXJA 1U5KA 1AN1I 2NU0I 1SGNI 2KMOA 2QQDA 4AMLA 2ODDA 4UXIA 4HGUA 1ULMA 5EX3A 3UFFA 1UVGA 3SGQI 1IY6A 2N1AB 2LB7A 2DKVA 4MPIA 1X4SA 2PQ8A 3HH2C 2DIPA 2E5RA 2GKRI 2X3TA 3B4VC 1H0ZA 3R5AA 2UZ3A 1BMOA 1M8BA 4E1PA 3FSYA 3R5CA 1LR9A 2GIVA 1OMTA 1BUSA 2QPOA 2GKVA 1P9GA 5CCLA 1FAQA 4B6DA 1NXUA 3OL0A 2JA1A 2YUUA 1WGCA 1MJ9A 1FY7A 1OYVI 1S20A 1CHOI 1TURA 1Y1BA 2J9RA 3MEKA 2NU3I 4GI3C 4UXHA 5HQ8A 5FUYA 1W3SA 2CJSC 2F3CI 1P9ZA 7WGAA 1V1HA 1FARA 1PTQA 3OXLA 5J8FA 5JHWC 2B0UC 1K7UA 1XBTA 3PDNA 5E3QA 1R79A 1WGTA 2SGPI 4A24A 4E1RA 1UHAA 1XX6A 2SGDI 3R5DA 2JZMA 3FSXA 2A20A 1K7VA 1K7TA 2ELIA 2JYYA 1SGEI 2ORWA 1TOTA 2W0TA 1N13A 1IW4A 1LR7A 1TBOA 1UUCA 1PPFI 2CWHA 1SGRI 1CT4I 4SGBI 2CWGA 2ERWA 1WKXA 1CSOI 1MT1A 5E3PA 1TIHA 1HJAI 3QWPA 2ROWA 3UGLA 4DNCA 2V1CA 1CT2I 2WGCA 1FYBA 2BUSA 5E3RA 2N52A
chains in the Genus database with same CATH topology
1TGSI 1V1IA 3VDUA 2K9HA 2QQCA 2FNFX 1HPTA 1IY5A 1TBNA 1Y8FA 1OVOA 2KMRA 1PJUA 1SGPI 3TJQA 2SGEI 2M5XA 2KCXA 5EX0A 1YU6C 3KY9A 1TUSA 3UEJA 2LEOA 2NU1I 2WVJA 3BJIA 4JCVE 2OD1A 4L9MA 1CGJI 2P6AC 5FUVA 1X74A 1KBEA 2LUYA 2V1CC 2ENNA 2JXDA 2KMPA 5DAEA 2VRWB 3RU0A 1VDDA 1CE3A 5FUXA 1SGDI 3QTLD 2GKTI 2L8EA 3UGDA 1SGQI 1CGII 1PTRA 2KMQA 3OXFA 2GVIA 3VE5A 3E2IA 1OMUA 2ENZA 1RFHA 2N17A 2WCYA 1DS2I 1PCEA 1W4RA 2YQPA 1KBFA 1Z7KB 1TBQR 3D00A 1KMAA 2XRCA 2QQ0A 3SGBI 3VDPA 1XA6A 2SGQI 1YTPA 2JW6A 5CCMA 2DB6A 1UVFA 2E73A 2QQEA 2ORVA 2NU4I 3SEKC 1SGYI 5FUWA 4FKDA 5HI7A 3UEYA 3OVOA 2ARPF 2J87A 3E59A 2N71A 2B8TA 1M8CA 1CT0I 1NUBA 1TBRR 2V53A 1DS3I 2OVOA 4OVOA 2NU2I 2L7XA 1R0RI 3CXLA 3UGIA 1Y1CA 1HDLA 2SGFI 3OXGA 3GOXA 3FC3A 1LR8A 4UXJA 1U5KA 1AN1I 2NU0I 1SGNI 2KMOA 2QQDA 2ODDA 4UXIA 4HGUA 5EX3A 3UFFA 1UVGA 3SGQI 1IY6A 2N1AB 1X4SA 3HH2C 2DIPA 2E5RA 2GKRI 3B4VC 1H0ZA 2UZ3A 1BMOA 1M8BA 4E1PA 1LR9A 1OMTA 1BUSA 2QPOA 2GKVA 1FAQA 5CCLA 4B6DA 3OL0A 2JA1A 2YUUA 1OYVI 2J9RA 1Y1BA 1CHOI 1TURA 3MEKA 4GI3C 4UXHA 2NU3I 5HQ8A 5FUYA 1W3SA 2CJSC 2F3CI 1V1HA 1FARA 1PTQA 3OXLA 5JHWC 2B0UC 1XBTA 3PDNA 4E1RA 1R79A 2SGPI 4A24A 1XX6A 2SGDI 2JZMA 2A20A 2ELIA 2JYYA 1SGEI 2ORWA 1TOTA 2W0TA 1N13A 1IW4A 1LR7A 1TBOA 1UUCA 1PPFI 1SGRI 1CT4I 4SGBI 2ERWA 1CSOI 1MT1A 1TIHA 1HJAI 3QWPA 2ROWA 3UGLA 2V1CA 1CT2I 1FYBA 2BUSA 2N52A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TGS I;  2QQC A;  1HPT A;  1IY5 A;  1OVO A;  2KMR A;  1PJU A;  1SGP I;  3TJQ A;  2SGE I;  2M5X A;  2KCX A;  1YU6 C;  1TUS A;  2LEO A;  2NU1 I;  1CGJ I;  2P6A C;  2JXD A;  2KMP A;  5DAE A;  1CE3 A;  1SGD I;  3QTL D;  2GKT I;  1SGQ I;  1CGI I;  2KMQ A;  1OMU A;  2N17 A;  2WCY A;  1DS2 I;  1PCE A;  1Z7K B;  1TBQ R;  1KMA A;  2XRC A;  3SGB I;  2SGQ I;  1YTP A;  1UVF A;  3SEK C;  2NU4 I;  1SGY I;  3OVO A;  2ARP F;  2N71 A;  1M8C A;  1CT0 I;  1NUB A;  1TBR R;  2V53 A;  1DS3 I;  2OVO A;  4OVO A;  2NU2 I;  1R0R I;  1HDL A;  1Y1C A;  2SGF I;  1LR8 A;  1AN1 I;  2NU0 I;  1SGN I;  2KMO A;  2QQD A;  4HGU A;  1UVG A;  3SGQ I;  1IY6 A;  3HH2 C;  2GKR I;  3B4V C;  1H0Z A;  1BMO A;  1M8B A;  1LR9 A;  1OMT A;  1BUS A;  2GKV A;  1OYV I;  4GI3 C;  1Y1B A;  1CHO I;  1TUR A;  2NU3 I;  2F3C I;  5JHW C;  2B0U C;  2SGP I;  2SGD I;  2JZM A;  2JYY A;  1SGE I;  1IW4 A;  1N13 A;  1LR7 A;  1UUC A;  1PPF I;  1SGR I;  1CT4 I;  4SGB I;  2ERW A;  1CSO I;  1MT1 A;  1TIH A;  1HJA I;  1CT2 I;  1FYB A;  2BUS A;  2N52 A; 
#chains in the Genus database with same CATH topology
 1TGS I;  1V1I A;  2UVO A;  1MJB A;  3VDU A;  2K9H A;  2QQC A;  2FNF X;  1HPT A;  3UOE A;  1TBN A;  1Y8F A;  1IY5 A;  1ULK A;  1OVO A;  2KMR A;  1PJU A;  1SGP I;  2RIJ A;  3TJQ A;  2SGE I;  2M5X A;  2KCX A;  5EX0 A;  1YU6 C;  3KY9 A;  1TUS A;  3UEJ A;  2LEO A;  2NU1 I;  2WVJ A;  2Y0M A;  3BJI A;  4JCV E;  2CWF A;  2OD1 A;  4L9M A;  1CGJ I;  2P6A C;  5FUV A;  3R5B A;  1X74 A;  1KBE A;  2LUY A;  2V1C C;  2ENN A;  2JXD A;  2KMP A;  5DAE A;  2VRW B;  3TO7 A;  3TO9 A;  3RU0 A;  1VDD A;  1HEV A;  3QAH A;  1CE3 A;  5FUX A;  1SGD I;  3QTL D;  2GKT I;  2L8E A;  1WTJ A;  3UGD A;  1SGQ I;  1CGI I;  1PTR A;  2KMQ A;  3OXF A;  1Q9B A;  2GVI A;  3VE5 A;  3E2I A;  1OMU A;  5J8C A;  2ENZ A;  1RFH A;  2N17 A;  2WCY A;  1DS2 I;  1PCE A;  1W4R A;  2YQP A;  1KBF A;  1Z7K B;  1TBQ R;  3D00 A;  1KMA A;  2OZU A;  3TO6 A;  2XRC A;  2QQ0 A;  3SGB I;  3TOB A;  3VDP A;  1XA6 A;  2SGQ I;  1YTP A;  2JW6 A;  3TOA A;  2DB6 A;  1UVF A;  2E73 A;  2QQE A;  5CCM A;  2ORV A;  2NU4 I;  3SEK C;  1SGY I;  5FUW A;  4FKD A;  2OU2 A;  5HI7 A;  3UEY A;  9WGA A;  3OVO A;  2ARP F;  2J87 A;  3E59 A;  2N71 A;  2B8T A;  1M8C A;  1CT0 I;  1NUB A;  1TBR R;  1ULN A;  1Z2I A;  2V53 A;  1DS3 I;  2OVO A;  4OVO A;  2NU2 I;  2X52 A;  2L7X A;  2RC4 A;  1R0R I;  3CXL A;  3UGI A;  1Y1C A;  1HDL A;  2SGF I;  3OXG A;  3GOX A;  4WP4 A;  3FC3 A;  1LR8 A;  1MJA A;  4UXJ A;  1U5K A;  1AN1 I;  2NU0 I;  1SGN I;  2KMO A;  2QQD A;  4AML A;  2ODD A;  4UXI A;  4HGU A;  1ULM A;  5EX3 A;  3UFF A;  1UVG A;  3SGQ I;  1IY6 A;  2N1A B;  2LB7 A;  2DKV A;  4MPI A;  1X4S A;  2PQ8 A;  3HH2 C;  2DIP A;  2E5R A;  2GKR I;  2X3T A;  3B4V C;  1H0Z A;  3R5A A;  2UZ3 A;  1BMO A;  1M8B A;  4E1P A;  3FSY A;  3R5C A;  1LR9 A;  2GIV A;  1OMT A;  1BUS A;  2QPO A;  2GKV A;  1P9G A;  5CCL A;  1FAQ A;  4B6D A;  1NXU A;  3OL0 A;  2JA1 A;  2YUU A;  1WGC A;  1MJ9 A;  1FY7 A;  1OYV I;  1S20 A;  1CHO I;  1TUR A;  1Y1B A;  2J9R A;  3MEK A;  2NU3 I;  4GI3 C;  4UXH A;  5HQ8 A;  5FUY A;  1W3S A;  2CJS C;  2F3C I;  1P9Z A;  7WGA A;  1V1H A;  1FAR A;  1PTQ A;  3OXL A;  5J8F A;  5JHW C;  2B0U C;  1K7U A;  1XBT A;  3PDN A;  5E3Q A;  1R79 A;  1WGT A;  2SGP I;  4A24 A;  4E1R A;  1UHA A;  1XX6 A;  2SGD I;  3R5D A;  2JZM A;  3FSX A;  2A20 A;  1K7V A;  1K7T A;  2ELI A;  2JYY A;  1SGE I;  2ORW A;  1TOT A;  2W0T A;  1N13 A;  1IW4 A;  1LR7 A;  1TBO A;  1UUC A;  1PPF I;  2CWH A;  1SGR I;  1CT4 I;  4SGB I;  2CWG A;  2ERW A;  1WKX A;  1CSO I;  1MT1 A;  5E3P A;  1TIH A;  1HJA I;  3QWP A;  2ROW A;  3UGL A;  4DNC A;  2V1C A;  1CT2 I;  2WGC A;  1FYB A;  2BUS A;  5E3R A;  2N52 A; 
#chains in the Genus database with same CATH homology
 1TGS I;  1V1I A;  3VDU A;  2K9H A;  2QQC A;  2FNF X;  1HPT A;  1IY5 A;  1TBN A;  1Y8F A;  1OVO A;  2KMR A;  1PJU A;  1SGP I;  3TJQ A;  2SGE I;  2M5X A;  2KCX A;  5EX0 A;  1YU6 C;  3KY9 A;  1TUS A;  3UEJ A;  2LEO A;  2NU1 I;  2WVJ A;  3BJI A;  4JCV E;  2OD1 A;  4L9M A;  1CGJ I;  2P6A C;  5FUV A;  1X74 A;  1KBE A;  2LUY A;  2V1C C;  2ENN A;  2JXD A;  2KMP A;  5DAE A;  2VRW B;  3RU0 A;  1VDD A;  1CE3 A;  5FUX A;  1SGD I;  3QTL D;  2GKT I;  2L8E A;  3UGD A;  1SGQ I;  1CGI I;  1PTR A;  2KMQ A;  3OXF A;  2GVI A;  3VE5 A;  3E2I A;  1OMU A;  2ENZ A;  1RFH A;  2N17 A;  2WCY A;  1DS2 I;  1PCE A;  1W4R A;  2YQP A;  1KBF A;  1Z7K B;  1TBQ R;  3D00 A;  1KMA A;  2XRC A;  2QQ0 A;  3SGB I;  3VDP A;  1XA6 A;  2SGQ I;  1YTP A;  2JW6 A;  5CCM A;  2DB6 A;  1UVF A;  2E73 A;  2QQE A;  2ORV A;  2NU4 I;  3SEK C;  1SGY I;  5FUW A;  4FKD A;  5HI7 A;  3UEY A;  3OVO A;  2ARP F;  2J87 A;  3E59 A;  2N71 A;  2B8T A;  1M8C A;  1CT0 I;  1NUB A;  1TBR R;  2V53 A;  1DS3 I;  2OVO A;  4OVO A;  2NU2 I;  2L7X A;  1R0R I;  3CXL A;  3UGI A;  1Y1C A;  1HDL A;  2SGF I;  3OXG A;  3GOX A;  3FC3 A;  1LR8 A;  4UXJ A;  1U5K A;  1AN1 I;  2NU0 I;  1SGN I;  2KMO A;  2QQD A;  2ODD A;  4UXI A;  4HGU A;  5EX3 A;  3UFF A;  1UVG A;  3SGQ I;  1IY6 A;  2N1A B;  1X4S A;  3HH2 C;  2DIP A;  2E5R A;  2GKR I;  3B4V C;  1H0Z A;  2UZ3 A;  1BMO A;  1M8B A;  4E1P A;  1LR9 A;  1OMT A;  1BUS A;  2QPO A;  2GKV A;  1FAQ A;  5CCL A;  4B6D A;  3OL0 A;  2JA1 A;  2YUU A;  1OYV I;  2J9R A;  1Y1B A;  1CHO I;  1TUR A;  3MEK A;  4GI3 C;  4UXH A;  2NU3 I;  5HQ8 A;  5FUY A;  1W3S A;  2CJS C;  2F3C I;  1V1H A;  1FAR A;  1PTQ A;  3OXL A;  5JHW C;  2B0U C;  1XBT A;  3PDN A;  4E1R A;  1R79 A;  2SGP I;  4A24 A;  1XX6 A;  2SGD I;  2JZM A;  2A20 A;  2ELI A;  2JYY A;  1SGE I;  2ORW A;  1TOT A;  2W0T A;  1N13 A;  1IW4 A;  1LR7 A;  1TBO A;  1UUC A;  1PPF I;  1SGR I;  1CT4 I;  4SGB I;  2ERW A;  1CSO I;  1MT1 A;  1TIH A;  1HJA I;  3QWP A;  2ROW A;  3UGL A;  2V1C A;  1CT2 I;  1FYB A;  2BUS A;  2N52 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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