2NU4I

Accommodation of positively-charged residues in a hydrophobic specificity pocket: crystal structures of sgpb in complex with omtky3 variants lys18i and arg18i
Total Genus 14
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
51
structure length
51
Chain Sequence
VDCSEYPKPACTKEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
rcsb
molecule tags Hydrolase
source organism Meleagris gallopavo
molecule keywords Streptogrisin B, Proteinase B
total genus 14
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 2006-11-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2nu4I00
1IY5A 1TBRR 1CT0I 1AN1I 2KMOA 2JYYA 1M8CA 1SGDI 1TIHA 2ARPF 1PPFI 1UUCA 2M5XA 1SGYI 4GI3C 1DS3I 2NU3I 1UVGA 3HH2C 3B4VC 1Y1BA 2B0UC 1HJAI 2KMPA 2NU1I 1H0ZA 2JXDA 1CE3A 4SGBI 2JZMA 2BUSA 1YTPA 1CT2I 3SGQI 1BUSA 1OMTA 1LR7A 1CGJI 5JHWC 1DS2I 1Z7KB 3SEKC 1N13A 1SGEI 2GKRI 3TJQA 1Y1CA 1HPTA 2F3CI 2KMRA 1MT1A 5DAEA 1CSOI 1CGII 2NU0I 1SGQI 1LR9A 2KMQA 1KMAA 1PJUA 2P6AC 2LEOA 1LR8A 2SGDI 1BMOA 1IY6A 2N71A 2XRCA 1UVFA 1SGRI 2SGPI 1M8BA 2OVOA 1SGNI 1YU6C 2SGQI 1TGSI 3OVOA 1TUSA 1HDLA 4OVOA 1IW4A 1NUBA 2NU2I 1SGPI 2QQCA 2SGFI 2SGEI 3QTLD 1CT4I 1FYBA 2QQDA 2GKTI 2N52A 2V53A 1TBQR 1OMUA 1PCEA 1TURA 2GKVA 2WCYA 2KCXA 3SGBI 2ERWA 2NU4I 1R0RI 2N17A 1CHOI 4HGUA 1OVOA 1OYVI
chains in the Genus database with same CATH superfamily
2QPOA 1IY5A 2ELIA 4WP4A 2GIVA 1TBRR 2J87A 1CT0I 1V1IA 3R5CA 1AN1I 2KMOA 2JYYA 3QWPA 5FUWA 4A24A 1M8CA 1VDDA 1SGDI 2L8EA 2UVOA 3VE5A 1TIHA 2QQ0A 2ARPF 1MJ9A 4FKDA 4DNCA 1PPFI 1TBNA 1UUCA 1WGTA 1P9ZA 5FUYA 2M5XA 2ENNA 3R5BA 1SGYI 1V1HA 4GI3C 1DS3I 2NU3I 1UVGA 3HH2C 3GOXA 5HI7A 4MPIA 3UEYA 3B4VC 1X74A 2LB7A 1RFHA 1TOTA 1ULKA 2N1AB 2V1CA 1Y1BA 5E3RA 1UHAA 1PTRA 2B0UC 1S20A 3OL0A 1W3SA 4E1PA 1HJAI 5EX3A 5J8FA 2A20A 2KMPA 1U5KA 2NU1I 4UXHA 1H0ZA 2YQPA 1K7TA 5FUXA 2E73A 2JXDA 1CE3A 4SGBI 3RU0A 1X4SA 2BUSA 2JZMA 2JA1A 3OXLA 1YTPA 1ULMA 1CT2I 2UZ3A 3SGQI 3TOBA 1BUSA 3FSYA 5HQ8A 2RIJA 1OMTA 3TOAA 1LR7A 1CGJI 2K9HA 5JHWC 1DS2I 1Z7KB 2JW6A 2W0TA 3SEKC 2J9RA 5J8CA 1N13A 1SGEI 2GKRI 3TJQA 1KBFA 1W4RA 1Y1CA 1HPTA 2DIPA 2F3CI 2KMRA 1MT1A 1P9GA 5DAEA 4B6DA 1CSOI 1CGII 2VRWB 3BJIA 2NU0I 1XBTA 1SGQI 2ROWA 2ORWA 1LR9A 2KMQA 4AMLA 7WGAA 1KMAA 3UGDA 1PJUA 2CWHA 2P6AC 2V1CC 2LEOA 3VDUA 1LR8A 3R5AA 1HEVA 1R79A 2SGDI 1BMOA 2Y0MA 3VDPA 2OD1A 9WGAA 2PQ8A 1IY6A 1K7VA 1Y8FA 2E5RA 2QQEA 2N71A 2XRCA 1UVFA 5FUVA 1SGRI 1FAQA 1TBOA 2SGPI 1M8BA 1WTJA 2B8TA 1MJAA 2OZUA 3KY9A 3R5DA 3D00A 2ODDA 2OVOA 1SGNI 1YU6C 2SGQI 2X52A 3FSXA 1TGSI 3OVOA 5E3PA 2DB6A 5CCLA 2CJSC 1TUSA 5E3QA 1HDLA 1WKXA 2ORVA 5EX0A 1NXUA 2ENZA 4OVOA 1NUBA 5CCMA 2NU2I 1SGPI 1IW4A 1WGCA 2YUUA 2QQCA 1FY7A 2SGFI 3OXFA 2DKVA 3TO7A 4UXJA 2SGEI 3UFFA 1XA6A 2GVIA 3UGIA 2RC4A 1K7UA 2WVJA 2CWGA 3TO9A 3TO6A 3QTLD 1CT4I 3FC3A 1FYBA 2QQDA 3PDNA 2GKTI 2N52A 4E1RA 2V53A 3MEKA 1TBQR 1OMUA 2LUYA 3OXGA 1PCEA 1TURA 4UXIA 1KBEA 2GKVA 4JCVE 2WCYA 2OU2A 3UOEA 2KCXA 3SGBI 1Q9BA 2ERWA 3E59A 1XX6A 3QAHA 1ULNA 1MJBA 2CWFA 1FARA 1R0RI 1PTQA 1CHOI 2FNFX 2N17A 2NU4I 2X3TA 4L9MA 3UEJA 1Z2IA 3CXLA 3E2IA 4HGUA 2L7XA 1OVOA 1OYVI 3UGLA 2WGCA
chains in the Genus database with same CATH topology
2QPOA 1IY5A 2ELIA 1TBRR 2J87A 1CT0I 1V1IA 1AN1I 2KMOA 2JYYA 3QWPA 5FUWA 4A24A 1M8CA 1VDDA 1SGDI 2L8EA 3VE5A 1TIHA 2QQ0A 2ARPF 4FKDA 1PPFI 1TBNA 1UUCA 5FUYA 2M5XA 2ENNA 1SGYI 1V1HA 4GI3C 1DS3I 2NU3I 1UVGA 3HH2C 3GOXA 5HI7A 3UEYA 3B4VC 1X74A 1RFHA 1TOTA 2N1AB 2V1CA 1Y1BA 1PTRA 2B0UC 4E1PA 3OL0A 1W3SA 1HJAI 5EX3A 2A20A 2KMPA 1U5KA 2NU1I 4UXHA 1H0ZA 2YQPA 5FUXA 2E73A 2JXDA 1CE3A 4SGBI 3RU0A 1X4SA 2BUSA 2JZMA 2JA1A 3OXLA 1YTPA 1CT2I 2UZ3A 3SGQI 1BUSA 1OMTA 1LR7A 1CGJI 2K9HA 5JHWC 1DS2I 1Z7KB 2JW6A 2W0TA 3SEKC 2J9RA 1N13A 1SGEI 2GKRI 3TJQA 1KBFA 1W4RA 1Y1CA 1HPTA 2DIPA 2F3CI 2KMRA 1MT1A 5DAEA 4B6DA 1CSOI 1CGII 2VRWB 3BJIA 2NU0I 1XBTA 1SGQI 2ROWA 2ORWA 1LR9A 2KMQA 1KMAA 3UGDA 1PJUA 2P6AC 2V1CC 2LEOA 3VDUA 1LR8A 1R79A 2SGDI 1BMOA 3VDPA 2OD1A 1IY6A 2E5RA 1Y8FA 2QQEA 2N71A 2XRCA 1UVFA 5FUVA 1SGRI 1FAQA 1TBOA 2SGPI 1M8BA 2B8TA 3KY9A 3D00A 2ODDA 2OVOA 1SGNI 1YU6C 2SGQI 1TGSI 3OVOA 5CCLA 2DB6A 2CJSC 1TUSA 1HDLA 2ORVA 5EX0A 5CCMA 2ENZA 4OVOA 1NUBA 1IW4A 2NU2I 1SGPI 2YUUA 2QQCA 2SGFI 3OXFA 4UXJA 2SGEI 3UFFA 1XA6A 2GVIA 3UGIA 2WVJA 3QTLD 1CT4I 3FC3A 1FYBA 2QQDA 3PDNA 2GKTI 2N52A 4E1RA 2V53A 3MEKA 1TBQR 1OMUA 2LUYA 3OXGA 1PCEA 1TURA 4UXIA 1KBEA 2GKVA 4JCVE 2WCYA 2KCXA 3SGBI 2ERWA 3E59A 1XX6A 2NU4I 1FARA 1R0RI 1PTQA 1CHOI 2FNFX 2N17A 4L9MA 3UEJA 3CXLA 3E2IA 4HGUA 5HQ8A 2L7XA 1OVOA 1OYVI 3UGLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IY5 A;  1TBR R;  1CT0 I;  1AN1 I;  2KMO A;  2JYY A;  1M8C A;  1SGD I;  1TIH A;  2ARP F;  1PPF I;  1UUC A;  2M5X A;  1SGY I;  4GI3 C;  1DS3 I;  2NU3 I;  1UVG A;  3HH2 C;  3B4V C;  1Y1B A;  2B0U C;  1HJA I;  2KMP A;  2NU1 I;  1H0Z A;  2JXD A;  1CE3 A;  4SGB I;  2JZM A;  2BUS A;  1YTP A;  1CT2 I;  3SGQ I;  1BUS A;  1OMT A;  1LR7 A;  1CGJ I;  5JHW C;  1DS2 I;  1Z7K B;  3SEK C;  1N13 A;  1SGE I;  2GKR I;  3TJQ A;  1Y1C A;  1HPT A;  2F3C I;  2KMR A;  1MT1 A;  5DAE A;  1CSO I;  1CGI I;  2NU0 I;  1SGQ I;  1LR9 A;  2KMQ A;  1KMA A;  1PJU A;  2P6A C;  2LEO A;  1LR8 A;  2SGD I;  1BMO A;  1IY6 A;  2N71 A;  2XRC A;  1UVF A;  1SGR I;  2SGP I;  1M8B A;  2OVO A;  1SGN I;  1YU6 C;  2SGQ I;  1TGS I;  3OVO A;  1TUS A;  1HDL A;  4OVO A;  1IW4 A;  1NUB A;  2NU2 I;  1SGP I;  2QQC A;  2SGF I;  2SGE I;  3QTL D;  1CT4 I;  1FYB A;  2QQD A;  2GKT I;  2N52 A;  2V53 A;  1TBQ R;  1OMU A;  1PCE A;  1TUR A;  2GKV A;  2WCY A;  2KCX A;  3SGB I;  2ERW A;  2NU4 I;  1R0R I;  2N17 A;  1CHO I;  4HGU A;  1OVO A;  1OYV I; 
#chains in the Genus database with same CATH topology
 2QPO A;  1IY5 A;  2ELI A;  4WP4 A;  2GIV A;  1TBR R;  2J87 A;  1CT0 I;  1V1I A;  3R5C A;  1AN1 I;  2KMO A;  2JYY A;  3QWP A;  5FUW A;  4A24 A;  1M8C A;  1VDD A;  1SGD I;  2L8E A;  2UVO A;  3VE5 A;  1TIH A;  2QQ0 A;  2ARP F;  1MJ9 A;  4FKD A;  4DNC A;  1PPF I;  1TBN A;  1UUC A;  1WGT A;  1P9Z A;  5FUY A;  2M5X A;  2ENN A;  3R5B A;  1SGY I;  1V1H A;  4GI3 C;  1DS3 I;  2NU3 I;  1UVG A;  3HH2 C;  3GOX A;  5HI7 A;  4MPI A;  3UEY A;  3B4V C;  1X74 A;  2LB7 A;  1RFH A;  1TOT A;  1ULK A;  2N1A B;  2V1C A;  1Y1B A;  5E3R A;  1UHA A;  1PTR A;  2B0U C;  1S20 A;  3OL0 A;  1W3S A;  4E1P A;  1HJA I;  5EX3 A;  5J8F A;  2A20 A;  2KMP A;  1U5K A;  2NU1 I;  4UXH A;  1H0Z A;  2YQP A;  1K7T A;  5FUX A;  2E73 A;  2JXD A;  1CE3 A;  4SGB I;  3RU0 A;  1X4S A;  2BUS A;  2JZM A;  2JA1 A;  3OXL A;  1YTP A;  1ULM A;  1CT2 I;  2UZ3 A;  3SGQ I;  3TOB A;  1BUS A;  3FSY A;  5HQ8 A;  2RIJ A;  1OMT A;  3TOA A;  1LR7 A;  1CGJ I;  2K9H A;  5JHW C;  1DS2 I;  1Z7K B;  2JW6 A;  2W0T A;  3SEK C;  2J9R A;  5J8C A;  1N13 A;  1SGE I;  2GKR I;  3TJQ A;  1KBF A;  1W4R A;  1Y1C A;  1HPT A;  2DIP A;  2F3C I;  2KMR A;  1MT1 A;  1P9G A;  5DAE A;  4B6D A;  1CSO I;  1CGI I;  2VRW B;  3BJI A;  2NU0 I;  1XBT A;  1SGQ I;  2ROW A;  2ORW A;  1LR9 A;  2KMQ A;  4AML A;  7WGA A;  1KMA A;  3UGD A;  1PJU A;  2CWH A;  2P6A C;  2V1C C;  2LEO A;  3VDU A;  1LR8 A;  3R5A A;  1HEV A;  1R79 A;  2SGD I;  1BMO A;  2Y0M A;  3VDP A;  2OD1 A;  9WGA A;  2PQ8 A;  1IY6 A;  1K7V A;  1Y8F A;  2E5R A;  2QQE A;  2N71 A;  2XRC A;  1UVF A;  5FUV A;  1SGR I;  1FAQ A;  1TBO A;  2SGP I;  1M8B A;  1WTJ A;  2B8T A;  1MJA A;  2OZU A;  3KY9 A;  3R5D A;  3D00 A;  2ODD A;  2OVO A;  1SGN I;  1YU6 C;  2SGQ I;  2X52 A;  3FSX A;  1TGS I;  3OVO A;  5E3P A;  2DB6 A;  5CCL A;  2CJS C;  1TUS A;  5E3Q A;  1HDL A;  1WKX A;  2ORV A;  5EX0 A;  1NXU A;  2ENZ A;  4OVO A;  1NUB A;  5CCM A;  2NU2 I;  1SGP I;  1IW4 A;  1WGC A;  2YUU A;  2QQC A;  1FY7 A;  2SGF I;  3OXF A;  2DKV A;  3TO7 A;  4UXJ A;  2SGE I;  3UFF A;  1XA6 A;  2GVI A;  3UGI A;  2RC4 A;  1K7U A;  2WVJ A;  2CWG A;  3TO9 A;  3TO6 A;  3QTL D;  1CT4 I;  3FC3 A;  1FYB A;  2QQD A;  3PDN A;  2GKT I;  2N52 A;  4E1R A;  2V53 A;  3MEK A;  1TBQ R;  1OMU A;  2LUY A;  3OXG A;  1PCE A;  1TUR A;  4UXI A;  1KBE A;  2GKV A;  4JCV E;  2WCY A;  2OU2 A;  3UOE A;  2KCX A;  3SGB I;  1Q9B A;  2ERW A;  3E59 A;  1XX6 A;  3QAH A;  1ULN A;  1MJB A;  2CWF A;  1FAR A;  1R0R I;  1PTQ A;  1CHO I;  2FNF X;  2N17 A;  2NU4 I;  2X3T A;  4L9M A;  3UEJ A;  1Z2I A;  3CXL A;  3E2I A;  4HGU A;  2L7X A;  1OVO A;  1OYV I;  3UGL A;  2WGC A; 
#chains in the Genus database with same CATH homology
 2QPO A;  1IY5 A;  2ELI A;  1TBR R;  2J87 A;  1CT0 I;  1V1I A;  1AN1 I;  2KMO A;  2JYY A;  3QWP A;  5FUW A;  4A24 A;  1M8C A;  1VDD A;  1SGD I;  2L8E A;  3VE5 A;  1TIH A;  2QQ0 A;  2ARP F;  4FKD A;  1PPF I;  1TBN A;  1UUC A;  5FUY A;  2M5X A;  2ENN A;  1SGY I;  1V1H A;  4GI3 C;  1DS3 I;  2NU3 I;  1UVG A;  3HH2 C;  3GOX A;  5HI7 A;  3UEY A;  3B4V C;  1X74 A;  1RFH A;  1TOT A;  2N1A B;  2V1C A;  1Y1B A;  1PTR A;  2B0U C;  4E1P A;  3OL0 A;  1W3S A;  1HJA I;  5EX3 A;  2A20 A;  2KMP A;  1U5K A;  2NU1 I;  4UXH A;  1H0Z A;  2YQP A;  5FUX A;  2E73 A;  2JXD A;  1CE3 A;  4SGB I;  3RU0 A;  1X4S A;  2BUS A;  2JZM A;  2JA1 A;  3OXL A;  1YTP A;  1CT2 I;  2UZ3 A;  3SGQ I;  1BUS A;  1OMT A;  1LR7 A;  1CGJ I;  2K9H A;  5JHW C;  1DS2 I;  1Z7K B;  2JW6 A;  2W0T A;  3SEK C;  2J9R A;  1N13 A;  1SGE I;  2GKR I;  3TJQ A;  1KBF A;  1W4R A;  1Y1C A;  1HPT A;  2DIP A;  2F3C I;  2KMR A;  1MT1 A;  5DAE A;  4B6D A;  1CSO I;  1CGI I;  2VRW B;  3BJI A;  2NU0 I;  1XBT A;  1SGQ I;  2ROW A;  2ORW A;  1LR9 A;  2KMQ A;  1KMA A;  3UGD A;  1PJU A;  2P6A C;  2V1C C;  2LEO A;  3VDU A;  1LR8 A;  1R79 A;  2SGD I;  1BMO A;  3VDP A;  2OD1 A;  1IY6 A;  2E5R A;  1Y8F A;  2QQE A;  2N71 A;  2XRC A;  1UVF A;  5FUV A;  1SGR I;  1FAQ A;  1TBO A;  2SGP I;  1M8B A;  2B8T A;  3KY9 A;  3D00 A;  2ODD A;  2OVO A;  1SGN I;  1YU6 C;  2SGQ I;  1TGS I;  3OVO A;  5CCL A;  2DB6 A;  2CJS C;  1TUS A;  1HDL A;  2ORV A;  5EX0 A;  5CCM A;  2ENZ A;  4OVO A;  1NUB A;  1IW4 A;  2NU2 I;  1SGP I;  2YUU A;  2QQC A;  2SGF I;  3OXF A;  4UXJ A;  2SGE I;  3UFF A;  1XA6 A;  2GVI A;  3UGI A;  2WVJ A;  3QTL D;  1CT4 I;  3FC3 A;  1FYB A;  2QQD A;  3PDN A;  2GKT I;  2N52 A;  4E1R A;  2V53 A;  3MEK A;  1TBQ R;  1OMU A;  2LUY A;  3OXG A;  1PCE A;  1TUR A;  4UXI A;  1KBE A;  2GKV A;  4JCV E;  2WCY A;  2KCX A;  3SGB I;  2ERW A;  3E59 A;  1XX6 A;  2NU4 I;  1FAR A;  1R0R I;  1PTQ A;  1CHO I;  2FNF X;  2N17 A;  4L9M A;  3UEJ A;  3CXL A;  3E2I A;  4HGU A;  5HQ8 A;  2L7X A;  1OVO A;  1OYV I;  3UGL A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...