2SGEI

Glu 18 variant of turkey ovomucoid inhibitor third domain complexed with streptomyces griseus proteinase b at ph 10.7
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
51
structure length
51
Chain Sequence
VDCSEYPKPACTEEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Water molecules participate in proteinase-inhibitor interactions: crystal structures of Leu18, Ala18, and Gly18 variants of turkey ovomucoid inhibitor third domain complexed with Streptomyces griseus proteinase B.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Meleagris gallopavo
molecule keywords Streptogrisin B
total genus 14
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 1999-03-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2sgeI00
1M8CA 3SEKC 3HH2C 2QQCA 1CSOI 1UUCA 1SGEI 1H0ZA 1SGRI 2GKVA 3B4VC 2SGPI 1Z7KB 2GKTI 1FYBA 2BUSA 1TURA 1HDLA 1SGQI 2SGFI 3SGQI 2N71A 2F3CI 1TUSA 2QQDA 2P6AC 1SGNI 2OVOA 1CHOI 1IY5A 1CT0I 1SGPI 2M5XA 5JHWC 2ERWA 2NU0I 1OMTA 2N52A 1LR7A 5DAEA 3OVOA 4OVOA 1TBQR 2GKRI 1SGDI 2N17A 1LR9A 2JYYA 1HPTA 1BUSA 1UVGA 2V53A 1N13A 2KMPA 2SGQI 1PPFI 1TIHA 2XRCA 3SGBI 2SGDI 1PJUA 1DS3I 1YTPA 2KCXA 1R0RI 2KMRA 1Y1BA 1PCEA 2JZMA 2NU2I 1AN1I 1OVOA 2SGEI 2KMOA 1CE3A 1OYVI 1M8BA 1YU6C 1SGYI 4GI3C 3TJQA 1KMAA 1CGII 2WCYA 1HJAI 1IY6A 1CT2I 2NU1I 4HGUA 1TBRR 2KMQA 2LEOA 2NU4I 1LR8A 1DS2I 1TGSI 1UVFA 1CT4I 1OMUA 1MT1A 2NU3I 1NUBA 1Y1CA 3QTLD 2JXDA 4SGBI 1IW4A 2ARPF 1BMOA 2B0UC 1CGJI
chains in the Genus database with same CATH superfamily
1M8CA 3SEKC 5FUVA 2CWHA 2OD1A 3OXLA 3HH2C 2QQCA 2UVOA 1CSOI 3FC3A 2N1AB 1PTRA 5HI7A 1NXUA 1K7UA 2A20A 1UUCA 1SGEI 2ENNA 4MPIA 1H0ZA 5J8FA 1SGRI 2V1CA 2GKVA 1FAQA 2OU2A 3B4VC 4B6DA 2SGPI 2UZ3A 1Z7KB 4UXIA 5E3PA 2GKTI 2RC4A 1WTJA 1Y8FA 2W0TA 3OXFA 2ELIA 2LUYA 2PQ8A 5FUYA 2CJSC 1X4SA 1Q9BA 2ROWA 3OL0A 2BUSA 1TURA 3R5CA 1FYBA 1HDLA 2LB7A 3TO6A 5FUXA 4L9MA 3D00A 2DKVA 1S20A 1SGQI 2DIPA 4JCVE 4E1RA 2SGFI 3R5DA 3SGQI 1MJAA 2N71A 2X52A 2L7XA 2F3CI 1TUSA 3FSYA 4WP4A 2QQDA 2P6AC 4UXHA 1SGNI 2JW6A 2OVOA 1CHOI 2YQPA 3CXLA 1CT0I 4A24A 1SGPI 2X3TA 2M5XA 3UEJA 5JHWC 1IY5A 1RFHA 2ERWA 2NU0I 4E1PA 1OMTA 2N52A 1LR7A 1HEVA 3OXGA 2QQEA 5DAEA 1K7TA 1MJBA 5E3RA 3OVOA 4OVOA 1TBQR 1XBTA 4FKDA 1P9GA 3RU0A 2GKRI 1SGDI 1V1HA 3UGLA 1FARA 2N17A 2ARPF 2FNFX 1LR9A 2CWGA 2JYYA 1HPTA 1BUSA 1XX6A 1UVGA 2V53A 1U5KA 1Z2IA 1N13A 2KMPA 2SGQI 4AMLA 2RIJA 1PPFI 1MJ9A 1TIHA 3UGIA 1ULKA 1PTQA 2XRCA 5FUWA 3SGBI 5HQ8A 2SGDI 1TBOA 2QPOA 3UGDA 1PJUA 5CCLA 1ULMA 3UOEA 1DS3I 5E3QA 2CWFA 5CCMA 1WKXA 1YTPA 4UXJA 2WVJA 2KCXA 1R0RI 1UHAA 3MEKA 2KMRA 1Y1BA 2E5RA 2QQ0A 2GVIA 2Y0MA 1R79A 1XA6A 2ORVA 2K9HA 2JA1A 3TOAA 2J9RA 1PCEA 2JZMA 3PDNA 1X74A 2NU2I 3TO9A 1AN1I 1OVOA 2SGEI 3GOXA 2KMOA 3E2IA 1CE3A 1OYVI 2DB6A 1M8BA 1FY7A 1YU6C 5EX0A 1W3SA 2OZUA 2L8EA 1SGYI 1KBFA 3QAHA 4GI3C 3TJQA 3BJIA 5J8CA 1KMAA 1CGII 2ENZA 2ODDA 2WCYA 3E59A 3TOBA 4DNCA 1HJAI 9WGAA 1V1IA 1IY6A 1ULNA 3UFFA 2WGCA 1CT2I 2NU1I 4HGUA 2VRWB 3FSXA 3TO7A 2B8TA 1TBRR 2GIVA 1WGTA 1TOTA 7WGAA 2KMQA 2E73A 2LEOA 2NU4I 3QWPA 3R5BA 1DS2I 1P9ZA 1TGSI 1UVFA 1CT4I 1WGCA 1VDDA 2ORWA 1K7VA 1KBEA 1OMUA 3KY9A 3R5AA 3VDPA 3VE5A 1MT1A 1NUBA 2NU3I 5EX3A 1Y1CA 2V1CC 2JXDA 3QTLD 4SGBI 2YUUA 2J87A 3VDUA 3UEYA 1IW4A 1W4RA 1LR8A 1BMOA 1TBNA 2B0UC 1CGJI
chains in the Genus database with same CATH topology
1M8CA 3SEKC 5FUVA 2OD1A 3OXLA 3HH2C 2QQCA 1CSOI 3FC3A 2N1AB 1PTRA 5HI7A 2A20A 1UUCA 1SGEI 2ENNA 1H0ZA 1SGRI 2V1CA 2GKVA 1FAQA 3B4VC 4B6DA 2SGPI 2UZ3A 1Z7KB 4UXIA 2GKTI 1Y8FA 2W0TA 3OXFA 2ELIA 2LUYA 5FUYA 2CJSC 1X4SA 2ROWA 3OL0A 1FYBA 2BUSA 1TURA 1HDLA 5FUXA 4L9MA 3D00A 2DIPA 1SGQI 4JCVE 4E1RA 2SGFI 3SGQI 2N71A 2L7XA 2F3CI 1TUSA 2QQDA 2P6AC 4UXHA 1SGNI 2JW6A 2OVOA 1CHOI 2YQPA 3CXLA 1CT0I 4A24A 1SGPI 3UEJA 2M5XA 5JHWC 1IY5A 1RFHA 2ERWA 2NU0I 4E1PA 1OMTA 2N52A 1LR7A 3OXGA 2QQEA 5DAEA 3OVOA 4OVOA 1TBQR 1XBTA 4FKDA 3RU0A 2GKRI 1SGDI 1V1HA 3UGLA 1FARA 2N17A 2FNFX 1LR9A 2JYYA 1HPTA 1BUSA 1XX6A 1UVGA 2V53A 1U5KA 1N13A 2KMPA 2SGQI 1PPFI 3UGIA 1TIHA 1PTQA 2XRCA 5FUWA 3SGBI 5HQ8A 2SGDI 1TBOA 2QPOA 3UGDA 1PJUA 5CCLA 1DS3I 5CCMA 1YTPA 4UXJA 2WVJA 2KCXA 1R0RI 3MEKA 2KMRA 1Y1BA 2E5RA 2QQ0A 2GVIA 1R79A 1XA6A 2ORVA 2K9HA 2JA1A 2J9RA 1PCEA 2JZMA 3PDNA 1X74A 2NU2I 1AN1I 1OVOA 2SGEI 3GOXA 2KMOA 3E2IA 1CE3A 1OYVI 2DB6A 1M8BA 1YU6C 5EX0A 1W3SA 2L8EA 1SGYI 1KBFA 4GI3C 3TJQA 3BJIA 1KMAA 1CGII 2ENZA 2ODDA 2WCYA 3E59A 1HJAI 1V1IA 1IY6A 3UFFA 1CT2I 2NU1I 4HGUA 2VRWB 2B8TA 1TBRR 1TOTA 2KMQA 2E73A 2LEOA 2NU4I 3QWPA 1LR8A 1DS2I 1TGSI 1UVFA 1CT4I 1VDDA 2ORWA 1KBEA 1OMUA 3KY9A 3VDPA 3VE5A 1MT1A 1NUBA 2NU3I 5EX3A 1Y1CA 2V1CC 2JXDA 3QTLD 4SGBI 2YUUA 2J87A 3VDUA 3UEYA 1IW4A 1W4RA 2ARPF 1BMOA 1TBNA 2B0UC 1CGJI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M8C A;  3SEK C;  3HH2 C;  2QQC A;  1CSO I;  1UUC A;  1SGE I;  1H0Z A;  1SGR I;  2GKV A;  3B4V C;  2SGP I;  1Z7K B;  2GKT I;  1FYB A;  2BUS A;  1TUR A;  1HDL A;  1SGQ I;  2SGF I;  3SGQ I;  2N71 A;  2F3C I;  1TUS A;  2QQD A;  2P6A C;  1SGN I;  2OVO A;  1CHO I;  1IY5 A;  1CT0 I;  1SGP I;  2M5X A;  5JHW C;  2ERW A;  2NU0 I;  1OMT A;  2N52 A;  1LR7 A;  5DAE A;  3OVO A;  4OVO A;  1TBQ R;  2GKR I;  1SGD I;  2N17 A;  1LR9 A;  2JYY A;  1HPT A;  1BUS A;  1UVG A;  2V53 A;  1N13 A;  2KMP A;  2SGQ I;  1PPF I;  1TIH A;  2XRC A;  3SGB I;  2SGD I;  1PJU A;  1DS3 I;  1YTP A;  2KCX A;  1R0R I;  2KMR A;  1Y1B A;  1PCE A;  2JZM A;  2NU2 I;  1AN1 I;  1OVO A;  2SGE I;  2KMO A;  1CE3 A;  1OYV I;  1M8B A;  1YU6 C;  1SGY I;  4GI3 C;  3TJQ A;  1KMA A;  1CGI I;  2WCY A;  1HJA I;  1IY6 A;  1CT2 I;  2NU1 I;  4HGU A;  1TBR R;  2KMQ A;  2LEO A;  2NU4 I;  1LR8 A;  1DS2 I;  1TGS I;  1UVF A;  1CT4 I;  1OMU A;  1MT1 A;  2NU3 I;  1NUB A;  1Y1C A;  3QTL D;  2JXD A;  4SGB I;  1IW4 A;  2ARP F;  1BMO A;  2B0U C;  1CGJ I; 
#chains in the Genus database with same CATH topology
 1M8C A;  3SEK C;  5FUV A;  2CWH A;  2OD1 A;  3OXL A;  3HH2 C;  2QQC A;  2UVO A;  1CSO I;  3FC3 A;  2N1A B;  1PTR A;  5HI7 A;  1NXU A;  1K7U A;  2A20 A;  1UUC A;  1SGE I;  2ENN A;  4MPI A;  1H0Z A;  5J8F A;  1SGR I;  2V1C A;  2GKV A;  1FAQ A;  2OU2 A;  3B4V C;  4B6D A;  2SGP I;  2UZ3 A;  1Z7K B;  4UXI A;  5E3P A;  2GKT I;  2RC4 A;  1WTJ A;  1Y8F A;  2W0T A;  3OXF A;  2ELI A;  2LUY A;  2PQ8 A;  5FUY A;  2CJS C;  1X4S A;  1Q9B A;  2ROW A;  3OL0 A;  2BUS A;  1TUR A;  3R5C A;  1FYB A;  1HDL A;  2LB7 A;  3TO6 A;  5FUX A;  4L9M A;  3D00 A;  2DKV A;  1S20 A;  1SGQ I;  2DIP A;  4JCV E;  4E1R A;  2SGF I;  3R5D A;  3SGQ I;  1MJA A;  2N71 A;  2X52 A;  2L7X A;  2F3C I;  1TUS A;  3FSY A;  4WP4 A;  2QQD A;  2P6A C;  4UXH A;  1SGN I;  2JW6 A;  2OVO A;  1CHO I;  2YQP A;  3CXL A;  1CT0 I;  4A24 A;  1SGP I;  2X3T A;  2M5X A;  3UEJ A;  5JHW C;  1IY5 A;  1RFH A;  2ERW A;  2NU0 I;  4E1P A;  1OMT A;  2N52 A;  1LR7 A;  1HEV A;  3OXG A;  2QQE A;  5DAE A;  1K7T A;  1MJB A;  5E3R A;  3OVO A;  4OVO A;  1TBQ R;  1XBT A;  4FKD A;  1P9G A;  3RU0 A;  2GKR I;  1SGD I;  1V1H A;  3UGL A;  1FAR A;  2N17 A;  2ARP F;  2FNF X;  1LR9 A;  2CWG A;  2JYY A;  1HPT A;  1BUS A;  1XX6 A;  1UVG A;  2V53 A;  1U5K A;  1Z2I A;  1N13 A;  2KMP A;  2SGQ I;  4AML A;  2RIJ A;  1PPF I;  1MJ9 A;  1TIH A;  3UGI A;  1ULK A;  1PTQ A;  2XRC A;  5FUW A;  3SGB I;  5HQ8 A;  2SGD I;  1TBO A;  2QPO A;  3UGD A;  1PJU A;  5CCL A;  1ULM A;  3UOE A;  1DS3 I;  5E3Q A;  2CWF A;  5CCM A;  1WKX A;  1YTP A;  4UXJ A;  2WVJ A;  2KCX A;  1R0R I;  1UHA A;  3MEK A;  2KMR A;  1Y1B A;  2E5R A;  2QQ0 A;  2GVI A;  2Y0M A;  1R79 A;  1XA6 A;  2ORV A;  2K9H A;  2JA1 A;  3TOA A;  2J9R A;  1PCE A;  2JZM A;  3PDN A;  1X74 A;  2NU2 I;  3TO9 A;  1AN1 I;  1OVO A;  2SGE I;  3GOX A;  2KMO A;  3E2I A;  1CE3 A;  1OYV I;  2DB6 A;  1M8B A;  1FY7 A;  1YU6 C;  5EX0 A;  1W3S A;  2OZU A;  2L8E A;  1SGY I;  1KBF A;  3QAH A;  4GI3 C;  3TJQ A;  3BJI A;  5J8C A;  1KMA A;  1CGI I;  2ENZ A;  2ODD A;  2WCY A;  3E59 A;  3TOB A;  4DNC A;  1HJA I;  9WGA A;  1V1I A;  1IY6 A;  1ULN A;  3UFF A;  2WGC A;  1CT2 I;  2NU1 I;  4HGU A;  2VRW B;  3FSX A;  3TO7 A;  2B8T A;  1TBR R;  2GIV A;  1WGT A;  1TOT A;  7WGA A;  2KMQ A;  2E73 A;  2LEO A;  2NU4 I;  3QWP A;  3R5B A;  1DS2 I;  1P9Z A;  1TGS I;  1UVF A;  1CT4 I;  1WGC A;  1VDD A;  2ORW A;  1K7V A;  1KBE A;  1OMU A;  3KY9 A;  3R5A A;  3VDP A;  3VE5 A;  1MT1 A;  1NUB A;  2NU3 I;  5EX3 A;  1Y1C A;  2V1C C;  2JXD A;  3QTL D;  4SGB I;  2YUU A;  2J87 A;  3VDU A;  3UEY A;  1IW4 A;  1W4R A;  1LR8 A;  1BMO A;  1TBN A;  2B0U C;  1CGJ I; 
#chains in the Genus database with same CATH homology
 1M8C A;  3SEK C;  5FUV A;  2OD1 A;  3OXL A;  3HH2 C;  2QQC A;  1CSO I;  3FC3 A;  2N1A B;  1PTR A;  5HI7 A;  2A20 A;  1UUC A;  1SGE I;  2ENN A;  1H0Z A;  1SGR I;  2V1C A;  2GKV A;  1FAQ A;  3B4V C;  4B6D A;  2SGP I;  2UZ3 A;  1Z7K B;  4UXI A;  2GKT I;  1Y8F A;  2W0T A;  3OXF A;  2ELI A;  2LUY A;  5FUY A;  2CJS C;  1X4S A;  2ROW A;  3OL0 A;  1FYB A;  2BUS A;  1TUR A;  1HDL A;  5FUX A;  4L9M A;  3D00 A;  2DIP A;  1SGQ I;  4JCV E;  4E1R A;  2SGF I;  3SGQ I;  2N71 A;  2L7X A;  2F3C I;  1TUS A;  2QQD A;  2P6A C;  4UXH A;  1SGN I;  2JW6 A;  2OVO A;  1CHO I;  2YQP A;  3CXL A;  1CT0 I;  4A24 A;  1SGP I;  3UEJ A;  2M5X A;  5JHW C;  1IY5 A;  1RFH A;  2ERW A;  2NU0 I;  4E1P A;  1OMT A;  2N52 A;  1LR7 A;  3OXG A;  2QQE A;  5DAE A;  3OVO A;  4OVO A;  1TBQ R;  1XBT A;  4FKD A;  3RU0 A;  2GKR I;  1SGD I;  1V1H A;  3UGL A;  1FAR A;  2N17 A;  2FNF X;  1LR9 A;  2JYY A;  1HPT A;  1BUS A;  1XX6 A;  1UVG A;  2V53 A;  1U5K A;  1N13 A;  2KMP A;  2SGQ I;  1PPF I;  3UGI A;  1TIH A;  1PTQ A;  2XRC A;  5FUW A;  3SGB I;  5HQ8 A;  2SGD I;  1TBO A;  2QPO A;  3UGD A;  1PJU A;  5CCL A;  1DS3 I;  5CCM A;  1YTP A;  4UXJ A;  2WVJ A;  2KCX A;  1R0R I;  3MEK A;  2KMR A;  1Y1B A;  2E5R A;  2QQ0 A;  2GVI A;  1R79 A;  1XA6 A;  2ORV A;  2K9H A;  2JA1 A;  2J9R A;  1PCE A;  2JZM A;  3PDN A;  1X74 A;  2NU2 I;  1AN1 I;  1OVO A;  2SGE I;  3GOX A;  2KMO A;  3E2I A;  1CE3 A;  1OYV I;  2DB6 A;  1M8B A;  1YU6 C;  5EX0 A;  1W3S A;  2L8E A;  1SGY I;  1KBF A;  4GI3 C;  3TJQ A;  3BJI A;  1KMA A;  1CGI I;  2ENZ A;  2ODD A;  2WCY A;  3E59 A;  1HJA I;  1V1I A;  1IY6 A;  3UFF A;  1CT2 I;  2NU1 I;  4HGU A;  2VRW B;  2B8T A;  1TBR R;  1TOT A;  2KMQ A;  2E73 A;  2LEO A;  2NU4 I;  3QWP A;  1LR8 A;  1DS2 I;  1TGS I;  1UVF A;  1CT4 I;  1VDD A;  2ORW A;  1KBE A;  1OMU A;  3KY9 A;  3VDP A;  3VE5 A;  1MT1 A;  1NUB A;  2NU3 I;  5EX3 A;  1Y1C A;  2V1C C;  2JXD A;  3QTL D;  4SGB I;  2YUU A;  2J87 A;  3VDU A;  3UEY A;  1IW4 A;  1W4R A;  2ARP F;  1BMO A;  1TBN A;  2B0U C;  1CGJ I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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