2SGFI

Phe 18 variant of turkey ovomucoid inhibitor third domain complexed with streptomyces griseus proteinase b
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
51
structure length
51
Chain Sequence
VDCSEYPKPACTFEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pHs
rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Meleagris gallopavo
molecule keywords Streptogrisin B
total genus 14
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 1999-03-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2sgfI00
2QQCA 2JZMA 1TBRR 2NU0I 1M8CA 2KMQA 3TJQA 2NU2I 2B0UC 2BUSA 2JYYA 4OVOA 1YU6C 2KCXA 1SGDI 1OVOA 2QQDA 1UVFA 1SGEI 2M5XA 1UUCA 1PJUA 1CE3A 2GKTI 2NU3I 1IW4A 1BUSA 1IY5A 2XRCA 2OVOA 2V53A 1SGYI 1CHOI 1TIHA 3HH2C 1CT2I 1HPTA 2SGEI 3QTLD 1FYBA 1CGJI 1UVGA 1Z7KB 5DAEA 1M8BA 1TBQR 1BMOA 2NU1I 1PPFI 2JXDA 1CT4I 1N13A 2SGPI 2SGFI 1SGQI 2NU4I 1TGSI 1TURA 4HGUA 2GKVA 1YTPA 1CSOI 1CT0I 1Y1CA 1IY6A 1OMUA 2ERWA 3B4VC 1SGNI 2LEOA 1Y1BA 1NUBA 2SGQI 3SGBI 2N71A 1SGRI 2N52A 1H0ZA 1OYVI 2KMPA 2WCYA 1LR8A 1DS2I 1KMAA 2SGDI 1OMTA 2KMOA 3SGQI 1CGII 1HDLA 1DS3I 1AN1I 2N17A 4SGBI 1LR9A 2P6AC 5JHWC 2KMRA 3OVOA 1LR7A 4GI3C 2ARPF 1TUSA 1PCEA 1SGPI 2F3CI 3SEKC 1HJAI 1R0RI 2GKRI 1MT1A
chains in the Genus database with same CATH superfamily
2QQCA 2LUYA 4B6DA 1W3SA 2PQ8A 5E3RA 1TBOA 2JZMA 1TBRR 2W0TA 1XX6A 2NU0I 4UXHA 1M8CA 2DKVA 5EX0A 1S20A 4A24A 2KMQA 3TJQA 1PTQA 2NU2I 3GOXA 3QAHA 1K7TA 2WVJA 2B0UC 4UXIA 2BUSA 2JYYA 4OVOA 2GVIA 2DIPA 1YU6C 3VDPA 3TOBA 2KCXA 1SGDI 1OVOA 2QQDA 1UVFA 2ORVA 2X52A 1SGEI 1NXUA 2M5XA 3OXGA 3PDNA 1UUCA 1X74A 1PJUA 1K7VA 2UZ3A 1CE3A 2GKTI 2NU3I 3FC3A 1IW4A 5HQ8A 1BUSA 1IY5A 2XRCA 3R5DA 2OVOA 4L9MA 2V53A 5FUWA 3VE5A 1SGYI 3OL0A 1CHOI 1TIHA 2QQ0A 5FUXA 3HH2C 1R79A 1CT2I 2DB6A 2E73A 1HPTA 2SGEI 3QTLD 9WGAA 1CGJI 2ENZA 1FYBA 2K9HA 1UVGA 1K7UA 1Z7KB 5DAEA 1M8BA 1PTRA 3R5CA 1TBQR 2OD1A 1BMOA 1WTJA 1XA6A 2NU1I 1W4RA 4MPIA 3UEJA 1PPFI 2JXDA 1CT4I 1N13A 2SGPI 3MEKA 2QPOA 1MJBA 2SGFI 2ROWA 5J8FA 2J87A 5E3PA 1KBFA 1XBTA 1HEVA 1SGQI 1P9GA 2NU4I 2X3TA 3TO7A 1TGSI 1Y8FA 3FSYA 1Q9BA 1TURA 3R5BA 4HGUA 2GKVA 2LB7A 1MJAA 1YTPA 3OXLA 1CSOI 1CT0I 1Y1CA 2JW6A 1IY6A 1OMUA 2RC4A 2ERWA 2CWFA 3B4VC 4AMLA 2L7XA 1SGNI 1WGCA 1TOTA 1ULNA 1U5KA 1V1IA 2QQEA 2LEOA 4JCVE 1Y1BA 4WP4A 3UFFA 2A20A 3KY9A 1NUBA 2SGQI 1ULMA 3SGBI 2N71A 2VRWB 3UOEA 1SGRI 2N52A 2B8TA 2WGCA 3OXFA 1X4SA 1TBNA 3TOAA 1RFHA 1Z2IA 1FARA 2CWGA 2ELIA 4UXJA 1H0ZA 3RU0A 2UVOA 1OYVI 2KMPA 2ODDA 2WCYA 1LR8A 1DS2I 4DNCA 1ULKA 1KMAA 3E59A 2Y0MA 2SGDI 1OMTA 2KMOA 2YUUA 3E2IA 3R5AA 2V1CA 4FKDA 3SGQI 1CGII 1WKXA 2V1CC 3TO6A 1DS3I 1AN1I 1HDLA 2GIVA 1VDDA 5E3QA 3CXLA 3UGDA 2N17A 4E1RA 4E1PA 2YQPA 4SGBI 2E5RA 3D00A 5FUYA 2JA1A 2RIJA 1LR9A 2P6AC 5JHWC 2ENNA 2FNFX 2OU2A 2ORWA 1FY7A 1MJ9A 2KMRA 3UGIA 3OVOA 1LR7A 1WGTA 5CCMA 3UEYA 3FSXA 1UHAA 2CJSC 4GI3C 2J9RA 5CCLA 3TO9A 1KBEA 2ARPF 3UGLA 3BJIA 2L8EA 1FAQA 1TUSA 3QWPA 1PCEA 1SGPI 5HI7A 7WGAA 2F3CI 5FUVA 2OZUA 5J8CA 1P9ZA 3SEKC 3VDUA 1HJAI 1V1HA 2CWHA 1R0RI 2N1AB 2GKRI 5EX3A 1MT1A
chains in the Genus database with same CATH topology
2QQCA 2LUYA 4B6DA 1W3SA 1TBOA 2JZMA 1TBRR 2W0TA 1XX6A 2NU0I 4UXHA 1M8CA 5EX0A 4A24A 2KMQA 3TJQA 1PTQA 2NU2I 3GOXA 4UXIA 2WVJA 2B0UC 2BUSA 2JYYA 4OVOA 2GVIA 2DIPA 1YU6C 3VDPA 2KCXA 1SGDI 1OVOA 2QQDA 1UVFA 2ORVA 1SGEI 3PDNA 2M5XA 3OXGA 1UUCA 1X74A 1PJUA 2UZ3A 1CE3A 2GKTI 2NU3I 3FC3A 1IW4A 5HQ8A 1BUSA 1IY5A 2XRCA 4L9MA 2OVOA 5FUWA 2V53A 3VE5A 1SGYI 3OL0A 1CHOI 1TIHA 2QQ0A 5FUXA 3HH2C 1R79A 1CT2I 2DB6A 2E73A 1HPTA 2SGEI 3QTLD 1FYBA 1CGJI 2ENZA 2K9HA 1UVGA 1Z7KB 5DAEA 1M8BA 1PTRA 1TBQR 2OD1A 1BMOA 1XA6A 2NU1I 1W4RA 3UEJA 1PPFI 2JXDA 1CT4I 1N13A 2SGPI 3MEKA 2QPOA 2SGFI 2ROWA 1KBFA 2J87A 1XBTA 1SGQI 2NU4I 1TGSI 1Y8FA 1TURA 4HGUA 2GKVA 1YTPA 3OXLA 1CSOI 1CT0I 1Y1CA 2JW6A 1IY6A 1OMUA 2ERWA 3B4VC 2L7XA 1SGNI 1TOTA 2QQEA 1U5KA 1V1IA 4JCVE 2LEOA 3UFFA 1Y1BA 2A20A 3KY9A 1NUBA 2SGQI 3SGBI 2N71A 2VRWB 1SGRI 2N52A 2B8TA 3OXFA 1X4SA 1TBNA 1RFHA 1FARA 2ELIA 4UXJA 1H0ZA 3RU0A 1OYVI 2KMPA 2ODDA 2WCYA 1LR8A 1DS2I 1KMAA 3E59A 2SGDI 1OMTA 2KMOA 2YUUA 3E2IA 4FKDA 2V1CA 3SGQI 1CGII 2V1CC 1HDLA 1DS3I 1AN1I 3UGDA 1VDDA 3CXLA 2N17A 4E1RA 4E1PA 2YQPA 4SGBI 2E5RA 3D00A 5FUYA 2JA1A 1LR9A 2P6AC 5JHWC 2ENNA 2FNFX 2ORWA 2KMRA 3UGIA 3OVOA 1LR7A 5CCMA 3UEYA 4GI3C 2CJSC 2J9RA 5CCLA 1KBEA 2ARPF 3UGLA 3BJIA 2L8EA 1FAQA 1TUSA 3QWPA 1PCEA 1SGPI 5HI7A 2F3CI 5FUVA 3SEKC 3VDUA 1HJAI 1V1HA 1R0RI 2N1AB 2GKRI 5EX3A 1MT1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QQC A;  2JZM A;  1TBR R;  2NU0 I;  1M8C A;  2KMQ A;  3TJQ A;  2NU2 I;  2B0U C;  2BUS A;  2JYY A;  4OVO A;  1YU6 C;  2KCX A;  1SGD I;  1OVO A;  2QQD A;  1UVF A;  1SGE I;  2M5X A;  1UUC A;  1PJU A;  1CE3 A;  2GKT I;  2NU3 I;  1IW4 A;  1BUS A;  1IY5 A;  2XRC A;  2OVO A;  2V53 A;  1SGY I;  1CHO I;  1TIH A;  3HH2 C;  1CT2 I;  1HPT A;  2SGE I;  3QTL D;  1FYB A;  1CGJ I;  1UVG A;  1Z7K B;  5DAE A;  1M8B A;  1TBQ R;  1BMO A;  2NU1 I;  1PPF I;  2JXD A;  1CT4 I;  1N13 A;  2SGP I;  2SGF I;  1SGQ I;  2NU4 I;  1TGS I;  1TUR A;  4HGU A;  2GKV A;  1YTP A;  1CSO I;  1CT0 I;  1Y1C A;  1IY6 A;  1OMU A;  2ERW A;  3B4V C;  1SGN I;  2LEO A;  1Y1B A;  1NUB A;  2SGQ I;  3SGB I;  2N71 A;  1SGR I;  2N52 A;  1H0Z A;  1OYV I;  2KMP A;  2WCY A;  1LR8 A;  1DS2 I;  1KMA A;  2SGD I;  1OMT A;  2KMO A;  3SGQ I;  1CGI I;  1HDL A;  1DS3 I;  1AN1 I;  2N17 A;  4SGB I;  1LR9 A;  2P6A C;  5JHW C;  2KMR A;  3OVO A;  1LR7 A;  4GI3 C;  2ARP F;  1TUS A;  1PCE A;  1SGP I;  2F3C I;  3SEK C;  1HJA I;  1R0R I;  2GKR I;  1MT1 A; 
#chains in the Genus database with same CATH topology
 2QQC A;  2LUY A;  4B6D A;  1W3S A;  2PQ8 A;  5E3R A;  1TBO A;  2JZM A;  1TBR R;  2W0T A;  1XX6 A;  2NU0 I;  4UXH A;  1M8C A;  2DKV A;  5EX0 A;  1S20 A;  4A24 A;  2KMQ A;  3TJQ A;  1PTQ A;  2NU2 I;  3GOX A;  3QAH A;  1K7T A;  2WVJ A;  2B0U C;  4UXI A;  2BUS A;  2JYY A;  4OVO A;  2GVI A;  2DIP A;  1YU6 C;  3VDP A;  3TOB A;  2KCX A;  1SGD I;  1OVO A;  2QQD A;  1UVF A;  2ORV A;  2X52 A;  1SGE I;  1NXU A;  2M5X A;  3OXG A;  3PDN A;  1UUC A;  1X74 A;  1PJU A;  1K7V A;  2UZ3 A;  1CE3 A;  2GKT I;  2NU3 I;  3FC3 A;  1IW4 A;  5HQ8 A;  1BUS A;  1IY5 A;  2XRC A;  3R5D A;  2OVO A;  4L9M A;  2V53 A;  5FUW A;  3VE5 A;  1SGY I;  3OL0 A;  1CHO I;  1TIH A;  2QQ0 A;  5FUX A;  3HH2 C;  1R79 A;  1CT2 I;  2DB6 A;  2E73 A;  1HPT A;  2SGE I;  3QTL D;  9WGA A;  1CGJ I;  2ENZ A;  1FYB A;  2K9H A;  1UVG A;  1K7U A;  1Z7K B;  5DAE A;  1M8B A;  1PTR A;  3R5C A;  1TBQ R;  2OD1 A;  1BMO A;  1WTJ A;  1XA6 A;  2NU1 I;  1W4R A;  4MPI A;  3UEJ A;  1PPF I;  2JXD A;  1CT4 I;  1N13 A;  2SGP I;  3MEK A;  2QPO A;  1MJB A;  2SGF I;  2ROW A;  5J8F A;  2J87 A;  5E3P A;  1KBF A;  1XBT A;  1HEV A;  1SGQ I;  1P9G A;  2NU4 I;  2X3T A;  3TO7 A;  1TGS I;  1Y8F A;  3FSY A;  1Q9B A;  1TUR A;  3R5B A;  4HGU A;  2GKV A;  2LB7 A;  1MJA A;  1YTP A;  3OXL A;  1CSO I;  1CT0 I;  1Y1C A;  2JW6 A;  1IY6 A;  1OMU A;  2RC4 A;  2ERW A;  2CWF A;  3B4V C;  4AML A;  2L7X A;  1SGN I;  1WGC A;  1TOT A;  1ULN A;  1U5K A;  1V1I A;  2QQE A;  2LEO A;  4JCV E;  1Y1B A;  4WP4 A;  3UFF A;  2A20 A;  3KY9 A;  1NUB A;  2SGQ I;  1ULM A;  3SGB I;  2N71 A;  2VRW B;  3UOE A;  1SGR I;  2N52 A;  2B8T A;  2WGC A;  3OXF A;  1X4S A;  1TBN A;  3TOA A;  1RFH A;  1Z2I A;  1FAR A;  2CWG A;  2ELI A;  4UXJ A;  1H0Z A;  3RU0 A;  2UVO A;  1OYV I;  2KMP A;  2ODD A;  2WCY A;  1LR8 A;  1DS2 I;  4DNC A;  1ULK A;  1KMA A;  3E59 A;  2Y0M A;  2SGD I;  1OMT A;  2KMO A;  2YUU A;  3E2I A;  3R5A A;  2V1C A;  4FKD A;  3SGQ I;  1CGI I;  1WKX A;  2V1C C;  3TO6 A;  1DS3 I;  1AN1 I;  1HDL A;  2GIV A;  1VDD A;  5E3Q A;  3CXL A;  3UGD A;  2N17 A;  4E1R A;  4E1P A;  2YQP A;  4SGB I;  2E5R A;  3D00 A;  5FUY A;  2JA1 A;  2RIJ A;  1LR9 A;  2P6A C;  5JHW C;  2ENN A;  2FNF X;  2OU2 A;  2ORW A;  1FY7 A;  1MJ9 A;  2KMR A;  3UGI A;  3OVO A;  1LR7 A;  1WGT A;  5CCM A;  3UEY A;  3FSX A;  1UHA A;  2CJS C;  4GI3 C;  2J9R A;  5CCL A;  3TO9 A;  1KBE A;  2ARP F;  3UGL A;  3BJI A;  2L8E A;  1FAQ A;  1TUS A;  3QWP A;  1PCE A;  1SGP I;  5HI7 A;  7WGA A;  2F3C I;  5FUV A;  2OZU A;  5J8C A;  1P9Z A;  3SEK C;  3VDU A;  1HJA I;  1V1H A;  2CWH A;  1R0R I;  2N1A B;  2GKR I;  5EX3 A;  1MT1 A; 
#chains in the Genus database with same CATH homology
 2QQC A;  2LUY A;  4B6D A;  1W3S A;  1TBO A;  2JZM A;  1TBR R;  2W0T A;  1XX6 A;  2NU0 I;  4UXH A;  1M8C A;  5EX0 A;  4A24 A;  2KMQ A;  3TJQ A;  1PTQ A;  2NU2 I;  3GOX A;  4UXI A;  2WVJ A;  2B0U C;  2BUS A;  2JYY A;  4OVO A;  2GVI A;  2DIP A;  1YU6 C;  3VDP A;  2KCX A;  1SGD I;  1OVO A;  2QQD A;  1UVF A;  2ORV A;  1SGE I;  3PDN A;  2M5X A;  3OXG A;  1UUC A;  1X74 A;  1PJU A;  2UZ3 A;  1CE3 A;  2GKT I;  2NU3 I;  3FC3 A;  1IW4 A;  5HQ8 A;  1BUS A;  1IY5 A;  2XRC A;  4L9M A;  2OVO A;  5FUW A;  2V53 A;  3VE5 A;  1SGY I;  3OL0 A;  1CHO I;  1TIH A;  2QQ0 A;  5FUX A;  3HH2 C;  1R79 A;  1CT2 I;  2DB6 A;  2E73 A;  1HPT A;  2SGE I;  3QTL D;  1FYB A;  1CGJ I;  2ENZ A;  2K9H A;  1UVG A;  1Z7K B;  5DAE A;  1M8B A;  1PTR A;  1TBQ R;  2OD1 A;  1BMO A;  1XA6 A;  2NU1 I;  1W4R A;  3UEJ A;  1PPF I;  2JXD A;  1CT4 I;  1N13 A;  2SGP I;  3MEK A;  2QPO A;  2SGF I;  2ROW A;  1KBF A;  2J87 A;  1XBT A;  1SGQ I;  2NU4 I;  1TGS I;  1Y8F A;  1TUR A;  4HGU A;  2GKV A;  1YTP A;  3OXL A;  1CSO I;  1CT0 I;  1Y1C A;  2JW6 A;  1IY6 A;  1OMU A;  2ERW A;  3B4V C;  2L7X A;  1SGN I;  1TOT A;  2QQE A;  1U5K A;  1V1I A;  4JCV E;  2LEO A;  3UFF A;  1Y1B A;  2A20 A;  3KY9 A;  1NUB A;  2SGQ I;  3SGB I;  2N71 A;  2VRW B;  1SGR I;  2N52 A;  2B8T A;  3OXF A;  1X4S A;  1TBN A;  1RFH A;  1FAR A;  2ELI A;  4UXJ A;  1H0Z A;  3RU0 A;  1OYV I;  2KMP A;  2ODD A;  2WCY A;  1LR8 A;  1DS2 I;  1KMA A;  3E59 A;  2SGD I;  1OMT A;  2KMO A;  2YUU A;  3E2I A;  4FKD A;  2V1C A;  3SGQ I;  1CGI I;  2V1C C;  1HDL A;  1DS3 I;  1AN1 I;  3UGD A;  1VDD A;  3CXL A;  2N17 A;  4E1R A;  4E1P A;  2YQP A;  4SGB I;  2E5R A;  3D00 A;  5FUY A;  2JA1 A;  1LR9 A;  2P6A C;  5JHW C;  2ENN A;  2FNF X;  2ORW A;  2KMR A;  3UGI A;  3OVO A;  1LR7 A;  5CCM A;  3UEY A;  4GI3 C;  2CJS C;  2J9R A;  5CCL A;  1KBE A;  2ARP F;  3UGL A;  3BJI A;  2L8E A;  1FAQ A;  1TUS A;  3QWP A;  1PCE A;  1SGP I;  5HI7 A;  2F3C I;  5FUV A;  3SEK C;  3VDU A;  1HJA I;  1V1H A;  1R0R I;  2N1A B;  2GKR I;  5EX3 A;  1MT1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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