2SGQI

Gln 18 variant of turkey ovomucoid inhibitor third domain complexed with streptomyces griseus proteinase b at ph 6.5
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
51
structure length
51
Chain Sequence
VDCSEYPKPACTQEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's
rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Meleagris gallopavo
molecule keywords Streptogrisin B
total genus 13
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 1999-03-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2sgqI00
1SGYI 2JZMA 3SGBI 2KMQA 1CGJI 2ERWA 4SGBI 1FYBA 1YU6C 1LR8A 2BUSA 2N52A 2JYYA 1UUCA 2NU4I 2SGPI 2SGEI 1AN1I 2V53A 1DS3I 2OVOA 1CE3A 1IY5A 1MT1A 2SGDI 1KMAA 1TGSI 1SGNI 3SGQI 1H0ZA 2N17A 1LR7A 2NU2I 2XRCA 1HPTA 1TIHA 1Y1BA 1Z7KB 1OMTA 2KMOA 1IY6A 1M8BA 1TUSA 2KMRA 2GKRI 1CT0I 2M5XA 2NU0I 1IW4A 1CT4I 1BMOA 2ARPF 1SGEI 1CHOI 3HH2C 1Y1CA 4OVOA 2NU1I 3QTLD 1CSOI 2SGFI 1CGII 3SEKC 4HGUA 2NU3I 1YTPA 2N71A 2P6AC 2QQDA 5DAEA 1N13A 1TBQR 2LEOA 1PPFI 1HDLA 1LR9A 1OMUA 2KMPA 5JHWC 2SGQI 1PCEA 1UVFA 2WCYA 1DS2I 4GI3C 1NUBA 1R0RI 1OYVI 1CT2I 1SGRI 2GKVA 2F3CI 1TBRR 1TURA 2KCXA 1SGDI 1HJAI 1M8CA 3TJQA 1BUSA 3OVOA 2GKTI 1SGPI 1PJUA 3B4VC 1SGQI 1OVOA 2B0UC 2QQCA 1UVGA 2JXDA
chains in the Genus database with same CATH superfamily
1K7TA 1SGYI 2QQ0A 2JZMA 3E2IA 1TBNA 3SGBI 2KMQA 1CGJI 5E3RA 2L7XA 2OU2A 2ERWA 3R5DA 1VDDA 4SGBI 3VDUA 1FYBA 1YU6C 3UEYA 3VE5A 1P9ZA 1LR8A 2BUSA 2N52A 3OL0A 3QWPA 1Y8FA 1Q9BA 1R79A 2V1CC 4L9MA 3RU0A 2QPOA 2JYYA 1UUCA 2NU4I 2SGPI 2W0TA 1K7VA 2ROWA 2SGEI 1XX6A 3PDNA 3QAHA 1AN1I 3R5CA 2CWGA 1TOTA 2V53A 1TBOA 2ODDA 1WKXA 2LB7A 3FC3A 2ENNA 1DS3I 5EX0A 2CWHA 3GOXA 2OVOA 4JCVE 4E1PA 1FAQA 1CE3A 1IY5A 1MT1A 1Z2IA 1X74A 2SGDI 1NXUA 1RFHA 1KMAA 1FARA 3VDPA 1TGSI 1SGNI 3SGQI 1H0ZA 2YQPA 2N17A 1LR7A 2NU2I 2XRCA 2E73A 9WGAA 3UOEA 2L8EA 3TOBA 2GIVA 2J87A 1KBFA 1HPTA 1X4SA 1TIHA 1Y1BA 1Z7KB 1OMTA 1MJAA 2ENZA 2KMOA 2UZ3A 3OXLA 1W3SA 1IY6A 1W4RA 1M8BA 1TUSA 2GKRI 2KMRA 1XBTA 5FUWA 5CCMA 1CT0I 2M5XA 3E59A 3KY9A 2DKVA 2NU0I 1IW4A 1HEVA 4B6DA 1CT4I 2PQ8A 5E3PA 2JA1A 1WGTA 1BMOA 2ARPF 1U5KA 1SGEI 2DB6A 1ULKA 3TO6A 1CHOI 3OXGA 5EX3A 4UXJA 2J9RA 1ULMA 3HH2C 1Y1CA 3D00A 4MPIA 1WGCA 4OVOA 2B8TA 2K9HA 3MEKA 7WGAA 1PTQA 2NU1I 2Y0MA 3QTLD 3FSXA 1CSOI 2OD1A 4FKDA 2SGFI 1MJBA 1XA6A 1CGII 3FSYA 2DIPA 2YUUA 4HGUA 2JW6A 3SEKC 3UGLA 2WVJA 2X52A 2NU3I 5FUVA 1FY7A 1YTPA 2N71A 2P6AC 2QQDA 5DAEA 3UGDA 1N13A 1TBQR 5FUXA 2LEOA 1PPFI 1S20A 3CXLA 3BJIA 4UXHA 1LR9A 1HDLA 2E5RA 1OMUA 2KMPA 3TO9A 5JHWC 2SGQI 1PCEA 3R5AA 4WP4A 4UXIA 1UVFA 5CCLA 1PTRA 2WCYA 3UGIA 2X3TA 2CWFA 1DS2I 3UFFA 1P9GA 4GI3C 4AMLA 2FNFX 2VRWB 4DNCA 1MJ9A 1NUBA 1KBEA 1R0RI 5J8FA 1V1IA 1V1HA 1OYVI 3R5BA 5HI7A 4E1RA 2ELIA 5HQ8A 1K7UA 1ULNA 2WGCA 5FUYA 2OZUA 1CT2I 1SGRI 3TOAA 4A24A 2GKVA 5J8CA 2V1CA 2F3CI 1TBRR 1TURA 2KCXA 1SGDI 2ORWA 5E3QA 1HJAI 1M8CA 1WTJA 2RC4A 3TJQA 2CJSC 3OXFA 2QQEA 3UEJA 2UVOA 2LUYA 3OVOA 1BUSA 2GKTI 1SGPI 2ORVA 1PJUA 3B4VC 1SGQI 1UHAA 1OVOA 2A20A 2B0UC 3TO7A 2QQCA 2RIJA 1UVGA 2JXDA 2GVIA 2N1AB
chains in the Genus database with same CATH topology
1SGYI 2QQ0A 2JZMA 3E2IA 1TBNA 3SGBI 2KMQA 1CGJI 2L7XA 2ERWA 1VDDA 4SGBI 3VDUA 1FYBA 1YU6C 3UEYA 3VE5A 1LR8A 2BUSA 2N52A 3OL0A 3QWPA 1Y8FA 2V1CC 1R79A 4L9MA 3RU0A 2QPOA 2JYYA 1UUCA 2NU4I 2SGPI 2W0TA 3UGIA 2ROWA 2SGEI 1XX6A 3PDNA 1AN1I 1TOTA 2V53A 1TBOA 2ODDA 3FC3A 2ENNA 1DS3I 5EX0A 3GOXA 2OVOA 4JCVE 4E1PA 1FAQA 1CE3A 1IY5A 1MT1A 1X74A 2SGDI 1RFHA 1KMAA 1FARA 3VDPA 1TGSI 1SGNI 3SGQI 1H0ZA 2YQPA 2N17A 1LR7A 2NU2I 2XRCA 2E73A 2L8EA 2J87A 1KBFA 1HPTA 1X4SA 1TIHA 1Y1BA 1Z7KB 1OMTA 2ENZA 2KMOA 2UZ3A 3OXLA 1W3SA 1IY6A 1M8BA 1TUSA 1W4RA 2GKRI 2KMRA 1XBTA 5FUWA 5CCMA 1CT0I 2M5XA 3E59A 3KY9A 2NU0I 1IW4A 4B6DA 1CT4I 2JA1A 1BMOA 2ARPF 1U5KA 1SGEI 2DB6A 1CHOI 3OXGA 5EX3A 4UXJA 2J9RA 3HH2C 1Y1CA 3D00A 4OVOA 2B8TA 2K9HA 3MEKA 1PTQA 2NU1I 3QTLD 1CSOI 2OD1A 4FKDA 2SGFI 1XA6A 1CGII 2DIPA 2YUUA 4HGUA 2JW6A 3SEKC 3UGLA 2WVJA 2NU3I 5FUVA 1YTPA 2N71A 2P6AC 2QQDA 5DAEA 3UGDA 1N13A 1TBQR 5FUXA 2LEOA 1PPFI 3CXLA 1HDLA 3BJIA 4UXHA 1LR9A 2E5RA 1OMUA 2KMPA 5JHWC 2SGQI 1PCEA 4UXIA 1UVFA 5CCLA 1PTRA 2WCYA 1DS2I 3UFFA 4GI3C 2FNFX 2VRWB 1NUBA 1KBEA 1R0RI 1V1IA 1V1HA 1OYVI 5HI7A 4E1RA 5HQ8A 2ELIA 5FUYA 1CT2I 1SGRI 4A24A 2GKVA 2V1CA 2F3CI 1TBRR 1TURA 2KCXA 1SGDI 2ORWA 1HJAI 1M8CA 3TJQA 2CJSC 3OXFA 2QQEA 3UEJA 1BUSA 2LUYA 3OVOA 2GKTI 1SGPI 2ORVA 1PJUA 3B4VC 1SGQI 1OVOA 2A20A 2B0UC 2QQCA 1UVGA 2JXDA 2GVIA 2N1AB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SGY I;  2JZM A;  3SGB I;  2KMQ A;  1CGJ I;  2ERW A;  4SGB I;  1FYB A;  1YU6 C;  1LR8 A;  2BUS A;  2N52 A;  2JYY A;  1UUC A;  2NU4 I;  2SGP I;  2SGE I;  1AN1 I;  2V53 A;  1DS3 I;  2OVO A;  1CE3 A;  1IY5 A;  1MT1 A;  2SGD I;  1KMA A;  1TGS I;  1SGN I;  3SGQ I;  1H0Z A;  2N17 A;  1LR7 A;  2NU2 I;  2XRC A;  1HPT A;  1TIH A;  1Y1B A;  1Z7K B;  1OMT A;  2KMO A;  1IY6 A;  1M8B A;  1TUS A;  2KMR A;  2GKR I;  1CT0 I;  2M5X A;  2NU0 I;  1IW4 A;  1CT4 I;  1BMO A;  2ARP F;  1SGE I;  1CHO I;  3HH2 C;  1Y1C A;  4OVO A;  2NU1 I;  3QTL D;  1CSO I;  2SGF I;  1CGI I;  3SEK C;  4HGU A;  2NU3 I;  1YTP A;  2N71 A;  2P6A C;  2QQD A;  5DAE A;  1N13 A;  1TBQ R;  2LEO A;  1PPF I;  1HDL A;  1LR9 A;  1OMU A;  2KMP A;  5JHW C;  2SGQ I;  1PCE A;  1UVF A;  2WCY A;  1DS2 I;  4GI3 C;  1NUB A;  1R0R I;  1OYV I;  1CT2 I;  1SGR I;  2GKV A;  2F3C I;  1TBR R;  1TUR A;  2KCX A;  1SGD I;  1HJA I;  1M8C A;  3TJQ A;  1BUS A;  3OVO A;  2GKT I;  1SGP I;  1PJU A;  3B4V C;  1SGQ I;  1OVO A;  2B0U C;  2QQC A;  1UVG A;  2JXD A; 
#chains in the Genus database with same CATH topology
 1K7T A;  1SGY I;  2QQ0 A;  2JZM A;  3E2I A;  1TBN A;  3SGB I;  2KMQ A;  1CGJ I;  5E3R A;  2L7X A;  2OU2 A;  2ERW A;  3R5D A;  1VDD A;  4SGB I;  3VDU A;  1FYB A;  1YU6 C;  3UEY A;  3VE5 A;  1P9Z A;  1LR8 A;  2BUS A;  2N52 A;  3OL0 A;  3QWP A;  1Y8F A;  1Q9B A;  1R79 A;  2V1C C;  4L9M A;  3RU0 A;  2QPO A;  2JYY A;  1UUC A;  2NU4 I;  2SGP I;  2W0T A;  1K7V A;  2ROW A;  2SGE I;  1XX6 A;  3PDN A;  3QAH A;  1AN1 I;  3R5C A;  2CWG A;  1TOT A;  2V53 A;  1TBO A;  2ODD A;  1WKX A;  2LB7 A;  3FC3 A;  2ENN A;  1DS3 I;  5EX0 A;  2CWH A;  3GOX A;  2OVO A;  4JCV E;  4E1P A;  1FAQ A;  1CE3 A;  1IY5 A;  1MT1 A;  1Z2I A;  1X74 A;  2SGD I;  1NXU A;  1RFH A;  1KMA A;  1FAR A;  3VDP A;  1TGS I;  1SGN I;  3SGQ I;  1H0Z A;  2YQP A;  2N17 A;  1LR7 A;  2NU2 I;  2XRC A;  2E73 A;  9WGA A;  3UOE A;  2L8E A;  3TOB A;  2GIV A;  2J87 A;  1KBF A;  1HPT A;  1X4S A;  1TIH A;  1Y1B A;  1Z7K B;  1OMT A;  1MJA A;  2ENZ A;  2KMO A;  2UZ3 A;  3OXL A;  1W3S A;  1IY6 A;  1W4R A;  1M8B A;  1TUS A;  2GKR I;  2KMR A;  1XBT A;  5FUW A;  5CCM A;  1CT0 I;  2M5X A;  3E59 A;  3KY9 A;  2DKV A;  2NU0 I;  1IW4 A;  1HEV A;  4B6D A;  1CT4 I;  2PQ8 A;  5E3P A;  2JA1 A;  1WGT A;  1BMO A;  2ARP F;  1U5K A;  1SGE I;  2DB6 A;  1ULK A;  3TO6 A;  1CHO I;  3OXG A;  5EX3 A;  4UXJ A;  2J9R A;  1ULM A;  3HH2 C;  1Y1C A;  3D00 A;  4MPI A;  1WGC A;  4OVO A;  2B8T A;  2K9H A;  3MEK A;  7WGA A;  1PTQ A;  2NU1 I;  2Y0M A;  3QTL D;  3FSX A;  1CSO I;  2OD1 A;  4FKD A;  2SGF I;  1MJB A;  1XA6 A;  1CGI I;  3FSY A;  2DIP A;  2YUU A;  4HGU A;  2JW6 A;  3SEK C;  3UGL A;  2WVJ A;  2X52 A;  2NU3 I;  5FUV A;  1FY7 A;  1YTP A;  2N71 A;  2P6A C;  2QQD A;  5DAE A;  3UGD A;  1N13 A;  1TBQ R;  5FUX A;  2LEO A;  1PPF I;  1S20 A;  3CXL A;  3BJI A;  4UXH A;  1LR9 A;  1HDL A;  2E5R A;  1OMU A;  2KMP A;  3TO9 A;  5JHW C;  2SGQ I;  1PCE A;  3R5A A;  4WP4 A;  4UXI A;  1UVF A;  5CCL A;  1PTR A;  2WCY A;  3UGI A;  2X3T A;  2CWF A;  1DS2 I;  3UFF A;  1P9G A;  4GI3 C;  4AML A;  2FNF X;  2VRW B;  4DNC A;  1MJ9 A;  1NUB A;  1KBE A;  1R0R I;  5J8F A;  1V1I A;  1V1H A;  1OYV I;  3R5B A;  5HI7 A;  4E1R A;  2ELI A;  5HQ8 A;  1K7U A;  1ULN A;  2WGC A;  5FUY A;  2OZU A;  1CT2 I;  1SGR I;  3TOA A;  4A24 A;  2GKV A;  5J8C A;  2V1C A;  2F3C I;  1TBR R;  1TUR A;  2KCX A;  1SGD I;  2ORW A;  5E3Q A;  1HJA I;  1M8C A;  1WTJ A;  2RC4 A;  3TJQ A;  2CJS C;  3OXF A;  2QQE A;  3UEJ A;  2UVO A;  2LUY A;  3OVO A;  1BUS A;  2GKT I;  1SGP I;  2ORV A;  1PJU A;  3B4V C;  1SGQ I;  1UHA A;  1OVO A;  2A20 A;  2B0U C;  3TO7 A;  2QQC A;  2RIJ A;  1UVG A;  2JXD A;  2GVI A;  2N1A B; 
#chains in the Genus database with same CATH homology
 1SGY I;  2QQ0 A;  2JZM A;  3E2I A;  1TBN A;  3SGB I;  2KMQ A;  1CGJ I;  2L7X A;  2ERW A;  1VDD A;  4SGB I;  3VDU A;  1FYB A;  1YU6 C;  3UEY A;  3VE5 A;  1LR8 A;  2BUS A;  2N52 A;  3OL0 A;  3QWP A;  1Y8F A;  2V1C C;  1R79 A;  4L9M A;  3RU0 A;  2QPO A;  2JYY A;  1UUC A;  2NU4 I;  2SGP I;  2W0T A;  3UGI A;  2ROW A;  2SGE I;  1XX6 A;  3PDN A;  1AN1 I;  1TOT A;  2V53 A;  1TBO A;  2ODD A;  3FC3 A;  2ENN A;  1DS3 I;  5EX0 A;  3GOX A;  2OVO A;  4JCV E;  4E1P A;  1FAQ A;  1CE3 A;  1IY5 A;  1MT1 A;  1X74 A;  2SGD I;  1RFH A;  1KMA A;  1FAR A;  3VDP A;  1TGS I;  1SGN I;  3SGQ I;  1H0Z A;  2YQP A;  2N17 A;  1LR7 A;  2NU2 I;  2XRC A;  2E73 A;  2L8E A;  2J87 A;  1KBF A;  1HPT A;  1X4S A;  1TIH A;  1Y1B A;  1Z7K B;  1OMT A;  2ENZ A;  2KMO A;  2UZ3 A;  3OXL A;  1W3S A;  1IY6 A;  1M8B A;  1TUS A;  1W4R A;  2GKR I;  2KMR A;  1XBT A;  5FUW A;  5CCM A;  1CT0 I;  2M5X A;  3E59 A;  3KY9 A;  2NU0 I;  1IW4 A;  4B6D A;  1CT4 I;  2JA1 A;  1BMO A;  2ARP F;  1U5K A;  1SGE I;  2DB6 A;  1CHO I;  3OXG A;  5EX3 A;  4UXJ A;  2J9R A;  3HH2 C;  1Y1C A;  3D00 A;  4OVO A;  2B8T A;  2K9H A;  3MEK A;  1PTQ A;  2NU1 I;  3QTL D;  1CSO I;  2OD1 A;  4FKD A;  2SGF I;  1XA6 A;  1CGI I;  2DIP A;  2YUU A;  4HGU A;  2JW6 A;  3SEK C;  3UGL A;  2WVJ A;  2NU3 I;  5FUV A;  1YTP A;  2N71 A;  2P6A C;  2QQD A;  5DAE A;  3UGD A;  1N13 A;  1TBQ R;  5FUX A;  2LEO A;  1PPF I;  3CXL A;  1HDL A;  3BJI A;  4UXH A;  1LR9 A;  2E5R A;  1OMU A;  2KMP A;  5JHW C;  2SGQ I;  1PCE A;  4UXI A;  1UVF A;  5CCL A;  1PTR A;  2WCY A;  1DS2 I;  3UFF A;  4GI3 C;  2FNF X;  2VRW B;  1NUB A;  1KBE A;  1R0R I;  1V1I A;  1V1H A;  1OYV I;  5HI7 A;  4E1R A;  5HQ8 A;  2ELI A;  5FUY A;  1CT2 I;  1SGR I;  4A24 A;  2GKV A;  2V1C A;  2F3C I;  1TBR R;  1TUR A;  2KCX A;  1SGD I;  2ORW A;  1HJA I;  1M8C A;  3TJQ A;  2CJS C;  3OXF A;  2QQE A;  3UEJ A;  1BUS A;  2LUY A;  3OVO A;  2GKT I;  1SGP I;  2ORV A;  1PJU A;  3B4V C;  1SGQ I;  1OVO A;  2A20 A;  2B0U C;  2QQC A;  1UVG A;  2JXD A;  2GVI A;  2N1A B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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