2WCYA

Nmr solution structure of factor i-like modules of complement c7.
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
155
structure length
155
Chain Sequence
GSHMNPLTQAVPKCQRWEKLQNSRCVCKMPYECGPSLDVCAQDERSKRILPLTVCKMHVLHCQGRNYTLTGRDSCTLPASAEKACGACPLWGKCDAESSKCVCREASECEEEGFSICVEVNGKEQTMSECEAGALRCRGQSISVTSIRPCAAETQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution Structure of Factor I-Like Modules from Complement C7 Reveals a Pair of Follistatin Domains in Compact Pseudosymmetric Arrangement.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords COMPLEMENT COMPONENT C7
total genus 27
structure length 155
sequence length 155
ec nomenclature
pdb deposition date 2009-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18434 Kazal_3 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2wcyA01
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2wcyA02
2SGDI 2N52A 1UVGA 2KMQA 2GKVA 3B4VC 1SGPI 1CHOI 2SGFI 2QQDA 1M8BA 2JYYA 1SGQI 1OVOA 1BMOA 2GKTI 5JHWC 1AN1I 1YTPA 1UUCA 4SGBI 1HDLA 1CT0I 1CT2I 2BUSA 1CSOI 1YU6C 2M5XA 1MT1A 2SGEI 2SGPI 1OMTA 1SGYI 1IW4A 1UVFA 1SGEI 1Y1CA 2WCYA 2NU3I 2OVOA 1TBQR 2JZMA 3SEKC 2NU0I 3SGBI 1BUSA 1CE3A 1LR7A 1PPFI 2KMPA 2NU4I 2XRCA 3SGQI 1TUSA 3OVOA 1TBRR 2B0UC 1SGDI 2F3CI 2N71A 1IY5A 2NU2I 1DS2I 4OVOA 2V53A 1PJUA 1TIHA 2KCXA 2KMRA 1IY6A 1FYBA 1DS3I 2LEOA 2KMOA 1LR9A 1R0RI 2ERWA 1CT4I 4HGUA 1LR8A 1Z7KB 2QQCA 3QTLD 1SGNI 1PCEA 5DAEA 2N17A 1OMUA 2JXDA 1NUBA 3HH2C 1M8CA 1Y1BA 1HPTA 1OYVI 4GI3C 2NU1I 1CGII 1SGRI 2SGQI 1N13A 1KMAA 1TURA 1CGJI 1TGSI 2GKRI 1HJAI 2ARPF 3TJQA 1H0ZA 2P6AC
chains in the Genus database with same CATH superfamily
2SGDI 1NXUA 2DKVA 3QAHA 1PTQA 1UVGA 2N52A 2KMQA 3OL0A 2GKVA 3CXLA 2RIJA 1V1IA 2RC4A 1HEVA 5J8CA 3B4VC 1SGPI 3D00A 2V1CA 1VDDA 4UXIA 1W4RA 3QWPA 2DIPA 2A20A 1CHOI 2SGFI 2B8TA 2QQDA 1M8BA 1TOTA 1SGQI 1K7UA 1OVOA 1BMOA 1WGTA 1WKXA 2E5RA 2JYYA 4E1PA 4E1RA 2GKTI 3VDPA 2W0TA 3UEYA 5JHWC 3OXFA 1AN1I 4UXJA 1YTPA 5EX3A 1R79A 1UUCA 4SGBI 2LB7A 2VRWB 1HDLA 1CT0I 2YQPA 3FSXA 4A24A 1CT2I 2BUSA 1CSOI 2K9HA 3KY9A 1Y8FA 1YU6C 4FKDA 2M5XA 2ROWA 1MT1A 2CWHA 2WGCA 3UEJA 2OD1A 4AMLA 7WGAA 2SGEI 1K7TA 2FNFX 2SGPI 1OMTA 2CWGA 1SGYI 1IW4A 1UVFA 1SGEI 1Y1CA 2WCYA 2CWFA 1PTRA 2NU3I 2OVOA 2JW6A 3TO6A 1TBQR 1S20A 2JZMA 3SEKC 1KBFA 2NU0I 3SGBI 2Y0MA 1BUSA 4L9MA 1LR7A 1CE3A 3TO9A 1PPFI 2KMPA 2DB6A 2NU4I 2GVIA 2XRCA 3TOAA 5HQ8A 2UZ3A 3SGQI 1MJAA 2OZUA 5CCMA 1TUSA 3OVOA 1TBRR 2B0UC 2CJSC 2J87A 5EX0A 5J8FA 3UGDA 1SGDI 2F3CI 2N1AB 1FAQA 1MJBA 1X74A 2N71A 1IY5A 3R5AA 5E3PA 1ULMA 1RFHA 1DS2I 1ULNA 2NU2I 2ORVA 2LUYA 2UVOA 2WVJA 2V53A 1UHAA 3MEKA 4OVOA 3VE5A 1PJUA 1TIHA 2KCXA 2KMRA 2ELIA 1WGCA 1IY6A 1FYBA 1DS3I 1U5KA 2ENNA 2ODDA 2L8EA 2LEOA 2KMOA 1LR9A 3OXLA 3R5BA 1TBNA 5FUXA 1R0RI 2V1CC 3RU0A 2ERWA 1CT4I 5FUVA 4DNCA 3GOXA 2ENZA 1FARA 1W3SA 1V1HA 4HGUA 1LR8A 2L7XA 1KBEA 4WP4A 1Z7KB 2QQCA 1K7VA 3QTLD 1SGNI 1PCEA 5DAEA 2X52A 2N17A 1OMUA 2JXDA 2ORWA 3OXGA 1XX6A 1NUBA 3HH2C 2X3TA 1M8CA 5HI7A 2YUUA 3E2IA 3VDUA 1X4SA 1Y1BA 1FY7A 3UGLA 1XBTA 3FC3A 1WTJA 9WGAA 1HPTA 1OYVI 2QPOA 1XA6A 2NU1I 4GI3C 2PQ8A 3UOEA 1CGII 1Q9BA 3PDNA 3UGIA 1SGRI 3TOBA 3E59A 2SGQI 1N13A 1P9GA 2OU2A 1KMAA 2JA1A 2J9RA 3R5CA 1H0ZA 1TURA 1CGJI 1TGSI 1MJ9A 4B6DA 2GKRI 1TBOA 2E73A 1HJAI 2QQ0A 2QQEA 4JCVE 5CCLA 5FUWA 3BJIA 2ARPF 3UFFA 4UXHA 5FUYA 3R5DA 3TO7A 3FSYA 1P9ZA 2GIVA 4MPIA 1ULKA 1Z2IA 2P6AC 3TJQA 5E3RA 5E3QA
chains in the Genus database with same CATH topology
2SGDI 1PTQA 1UVGA 2N52A 2KMQA 3OL0A 2GKVA 3CXLA 1V1IA 3B4VC 1SGPI 3D00A 2V1CA 1VDDA 1W4RA 3QWPA 2DIPA 2A20A 1CHOI 2SGFI 2B8TA 2QQDA 1M8BA 1TOTA 1SGQI 2JYYA 1OVOA 1BMOA 2E5RA 4UXIA 4E1PA 4E1RA 2GKTI 3VDPA 2W0TA 3UEYA 5JHWC 3OXFA 1AN1I 4UXJA 1YTPA 5EX3A 1R79A 1UUCA 4SGBI 2VRWB 1HDLA 1CT0I 2YQPA 4A24A 1CT2I 2BUSA 1CSOI 2K9HA 3KY9A 1Y8FA 1YU6C 4FKDA 2M5XA 2ROWA 1MT1A 3UEJA 2OD1A 2SGEI 2FNFX 2SGPI 1OMTA 1SGYI 1IW4A 1UVFA 1SGEI 1Y1CA 2WCYA 1PTRA 2NU3I 2OVOA 2JW6A 1TBQR 2JZMA 3SEKC 1KBFA 2NU0I 3SGBI 1BUSA 4L9MA 1LR7A 1CE3A 1PPFI 2KMPA 2DB6A 2NU4I 2GVIA 2XRCA 5HQ8A 2UZ3A 3SGQI 5CCMA 1TUSA 3OVOA 1TBRR 2B0UC 2CJSC 2J87A 5EX0A 1FAQA 3UGDA 1SGDI 2F3CI 2N1AB 1X74A 2N71A 1IY5A 1RFHA 1DS2I 2NU2I 2ORVA 2WVJA 2LUYA 3MEKA 4OVOA 2V53A 3VE5A 1PJUA 1TIHA 2KCXA 2KMRA 2ELIA 1IY6A 1FYBA 1DS3I 1U5KA 2ENNA 2ODDA 2L8EA 2LEOA 2KMOA 1LR9A 3OXLA 1TBNA 5FUXA 1R0RI 2V1CC 3RU0A 2ERWA 1CT4I 5FUVA 3GOXA 2ENZA 1FARA 1W3SA 1V1HA 4HGUA 1LR8A 2L7XA 1KBEA 1Z7KB 2QQCA 3QTLD 1SGNI 1PCEA 5DAEA 2N17A 1OMUA 2JXDA 2ORWA 3OXGA 1XX6A 1NUBA 3HH2C 1M8CA 5HI7A 2YUUA 3E2IA 3VDUA 1X4SA 1Y1BA 3UGLA 1XBTA 3FC3A 1HPTA 1OYVI 2QPOA 1XA6A 2NU1I 4GI3C 1CGII 3UGIA 3PDNA 1SGRI 3E59A 2SGQI 1N13A 1KMAA 2JA1A 2J9RA 1TURA 1CGJI 1TGSI 4B6DA 2GKRI 1TBOA 2E73A 1HJAI 2QQ0A 2QQEA 4JCVE 5CCLA 5FUWA 3BJIA 2ARPF 3UFFA 4UXHA 5FUYA 3TJQA 1H0ZA 2P6AC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2SGD I;  2N52 A;  1UVG A;  2KMQ A;  2GKV A;  3B4V C;  1SGP I;  1CHO I;  2SGF I;  2QQD A;  1M8B A;  2JYY A;  1SGQ I;  1OVO A;  1BMO A;  2GKT I;  5JHW C;  1AN1 I;  1YTP A;  1UUC A;  4SGB I;  1HDL A;  1CT0 I;  1CT2 I;  2BUS A;  1CSO I;  1YU6 C;  2M5X A;  1MT1 A;  2SGE I;  2SGP I;  1OMT A;  1SGY I;  1IW4 A;  1UVF A;  1SGE I;  1Y1C A;  2WCY A;  2NU3 I;  2OVO A;  1TBQ R;  2JZM A;  3SEK C;  2NU0 I;  3SGB I;  1BUS A;  1CE3 A;  1LR7 A;  1PPF I;  2KMP A;  2NU4 I;  2XRC A;  3SGQ I;  1TUS A;  3OVO A;  1TBR R;  2B0U C;  1SGD I;  2F3C I;  2N71 A;  1IY5 A;  2NU2 I;  1DS2 I;  4OVO A;  2V53 A;  1PJU A;  1TIH A;  2KCX A;  2KMR A;  1IY6 A;  1FYB A;  1DS3 I;  2LEO A;  2KMO A;  1LR9 A;  1R0R I;  2ERW A;  1CT4 I;  4HGU A;  1LR8 A;  1Z7K B;  2QQC A;  3QTL D;  1SGN I;  1PCE A;  5DAE A;  2N17 A;  1OMU A;  2JXD A;  1NUB A;  3HH2 C;  1M8C A;  1Y1B A;  1HPT A;  1OYV I;  4GI3 C;  2NU1 I;  1CGI I;  1SGR I;  2SGQ I;  1N13 A;  1KMA A;  1TUR A;  1CGJ I;  1TGS I;  2GKR I;  1HJA I;  2ARP F;  3TJQ A;  1H0Z A;  2P6A C; 
#chains in the Genus database with same CATH topology
 2SGD I;  1NXU A;  2DKV A;  3QAH A;  1PTQ A;  1UVG A;  2N52 A;  2KMQ A;  3OL0 A;  2GKV A;  3CXL A;  2RIJ A;  1V1I A;  2RC4 A;  1HEV A;  5J8C A;  3B4V C;  1SGP I;  3D00 A;  2V1C A;  1VDD A;  4UXI A;  1W4R A;  3QWP A;  2DIP A;  2A20 A;  1CHO I;  2SGF I;  2B8T A;  2QQD A;  1M8B A;  1TOT A;  1SGQ I;  1K7U A;  1OVO A;  1BMO A;  1WGT A;  1WKX A;  2E5R A;  2JYY A;  4E1P A;  4E1R A;  2GKT I;  3VDP A;  2W0T A;  3UEY A;  5JHW C;  3OXF A;  1AN1 I;  4UXJ A;  1YTP A;  5EX3 A;  1R79 A;  1UUC A;  4SGB I;  2LB7 A;  2VRW B;  1HDL A;  1CT0 I;  2YQP A;  3FSX A;  4A24 A;  1CT2 I;  2BUS A;  1CSO I;  2K9H A;  3KY9 A;  1Y8F A;  1YU6 C;  4FKD A;  2M5X A;  2ROW A;  1MT1 A;  2CWH A;  2WGC A;  3UEJ A;  2OD1 A;  4AML A;  7WGA A;  2SGE I;  1K7T A;  2FNF X;  2SGP I;  1OMT A;  2CWG A;  1SGY I;  1IW4 A;  1UVF A;  1SGE I;  1Y1C A;  2WCY A;  2CWF A;  1PTR A;  2NU3 I;  2OVO A;  2JW6 A;  3TO6 A;  1TBQ R;  1S20 A;  2JZM A;  3SEK C;  1KBF A;  2NU0 I;  3SGB I;  2Y0M A;  1BUS A;  4L9M A;  1LR7 A;  1CE3 A;  3TO9 A;  1PPF I;  2KMP A;  2DB6 A;  2NU4 I;  2GVI A;  2XRC A;  3TOA A;  5HQ8 A;  2UZ3 A;  3SGQ I;  1MJA A;  2OZU A;  5CCM A;  1TUS A;  3OVO A;  1TBR R;  2B0U C;  2CJS C;  2J87 A;  5EX0 A;  5J8F A;  3UGD A;  1SGD I;  2F3C I;  2N1A B;  1FAQ A;  1MJB A;  1X74 A;  2N71 A;  1IY5 A;  3R5A A;  5E3P A;  1ULM A;  1RFH A;  1DS2 I;  1ULN A;  2NU2 I;  2ORV A;  2LUY A;  2UVO A;  2WVJ A;  2V53 A;  1UHA A;  3MEK A;  4OVO A;  3VE5 A;  1PJU A;  1TIH A;  2KCX A;  2KMR A;  2ELI A;  1WGC A;  1IY6 A;  1FYB A;  1DS3 I;  1U5K A;  2ENN A;  2ODD A;  2L8E A;  2LEO A;  2KMO A;  1LR9 A;  3OXL A;  3R5B A;  1TBN A;  5FUX A;  1R0R I;  2V1C C;  3RU0 A;  2ERW A;  1CT4 I;  5FUV A;  4DNC A;  3GOX A;  2ENZ A;  1FAR A;  1W3S A;  1V1H A;  4HGU A;  1LR8 A;  2L7X A;  1KBE A;  4WP4 A;  1Z7K B;  2QQC A;  1K7V A;  3QTL D;  1SGN I;  1PCE A;  5DAE A;  2X52 A;  2N17 A;  1OMU A;  2JXD A;  2ORW A;  3OXG A;  1XX6 A;  1NUB A;  3HH2 C;  2X3T A;  1M8C A;  5HI7 A;  2YUU A;  3E2I A;  3VDU A;  1X4S A;  1Y1B A;  1FY7 A;  3UGL A;  1XBT A;  3FC3 A;  1WTJ A;  9WGA A;  1HPT A;  1OYV I;  2QPO A;  1XA6 A;  2NU1 I;  4GI3 C;  2PQ8 A;  3UOE A;  1CGI I;  1Q9B A;  3PDN A;  3UGI A;  1SGR I;  3TOB A;  3E59 A;  2SGQ I;  1N13 A;  1P9G A;  2OU2 A;  1KMA A;  2JA1 A;  2J9R A;  3R5C A;  1H0Z A;  1TUR A;  1CGJ I;  1TGS I;  1MJ9 A;  4B6D A;  2GKR I;  1TBO A;  2E73 A;  1HJA I;  2QQ0 A;  2QQE A;  4JCV E;  5CCL A;  5FUW A;  3BJI A;  2ARP F;  3UFF A;  4UXH A;  5FUY A;  3R5D A;  3TO7 A;  3FSY A;  1P9Z A;  2GIV A;  4MPI A;  1ULK A;  1Z2I A;  2P6A C;  3TJQ A;  5E3R A;  5E3Q A; 
#chains in the Genus database with same CATH homology
 2SGD I;  1PTQ A;  1UVG A;  2N52 A;  2KMQ A;  3OL0 A;  2GKV A;  3CXL A;  1V1I A;  3B4V C;  1SGP I;  3D00 A;  2V1C A;  1VDD A;  1W4R A;  3QWP A;  2DIP A;  2A20 A;  1CHO I;  2SGF I;  2B8T A;  2QQD A;  1M8B A;  1TOT A;  1SGQ I;  2JYY A;  1OVO A;  1BMO A;  2E5R A;  4UXI A;  4E1P A;  4E1R A;  2GKT I;  3VDP A;  2W0T A;  3UEY A;  5JHW C;  3OXF A;  1AN1 I;  4UXJ A;  1YTP A;  5EX3 A;  1R79 A;  1UUC A;  4SGB I;  2VRW B;  1HDL A;  1CT0 I;  2YQP A;  4A24 A;  1CT2 I;  2BUS A;  1CSO I;  2K9H A;  3KY9 A;  1Y8F A;  1YU6 C;  4FKD A;  2M5X A;  2ROW A;  1MT1 A;  3UEJ A;  2OD1 A;  2SGE I;  2FNF X;  2SGP I;  1OMT A;  1SGY I;  1IW4 A;  1UVF A;  1SGE I;  1Y1C A;  2WCY A;  1PTR A;  2NU3 I;  2OVO A;  2JW6 A;  1TBQ R;  2JZM A;  3SEK C;  1KBF A;  2NU0 I;  3SGB I;  1BUS A;  4L9M A;  1LR7 A;  1CE3 A;  1PPF I;  2KMP A;  2DB6 A;  2NU4 I;  2GVI A;  2XRC A;  5HQ8 A;  2UZ3 A;  3SGQ I;  5CCM A;  1TUS A;  3OVO A;  1TBR R;  2B0U C;  2CJS C;  2J87 A;  5EX0 A;  1FAQ A;  3UGD A;  1SGD I;  2F3C I;  2N1A B;  1X74 A;  2N71 A;  1IY5 A;  1RFH A;  1DS2 I;  2NU2 I;  2ORV A;  2WVJ A;  2LUY A;  3MEK A;  4OVO A;  2V53 A;  3VE5 A;  1PJU A;  1TIH A;  2KCX A;  2KMR A;  2ELI A;  1IY6 A;  1FYB A;  1DS3 I;  1U5K A;  2ENN A;  2ODD A;  2L8E A;  2LEO A;  2KMO A;  1LR9 A;  3OXL A;  1TBN A;  5FUX A;  1R0R I;  2V1C C;  3RU0 A;  2ERW A;  1CT4 I;  5FUV A;  3GOX A;  2ENZ A;  1FAR A;  1W3S A;  1V1H A;  4HGU A;  1LR8 A;  2L7X A;  1KBE A;  1Z7K B;  2QQC A;  3QTL D;  1SGN I;  1PCE A;  5DAE A;  2N17 A;  1OMU A;  2JXD A;  2ORW A;  3OXG A;  1XX6 A;  1NUB A;  3HH2 C;  1M8C A;  5HI7 A;  2YUU A;  3E2I A;  3VDU A;  1X4S A;  1Y1B A;  3UGL A;  1XBT A;  3FC3 A;  1HPT A;  1OYV I;  2QPO A;  1XA6 A;  2NU1 I;  4GI3 C;  1CGI I;  3UGI A;  3PDN A;  1SGR I;  3E59 A;  2SGQ I;  1N13 A;  1KMA A;  2JA1 A;  2J9R A;  1TUR A;  1CGJ I;  1TGS I;  4B6D A;  2GKR I;  1TBO A;  2E73 A;  1HJA I;  2QQ0 A;  2QQE A;  4JCV E;  5CCL A;  5FUW A;  3BJI A;  2ARP F;  3UFF A;  4UXH A;  5FUY A;  3TJQ A;  1H0Z A;  2P6A C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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