3OL0A

Crystal structure of monofoil-4p homo-trimer: de novo designed monomer trefoil-fold sub-domain which forms homo-trimer assembly
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
43
structure length
43
Chain Sequence
HHHPVLLKSTETGQYLRINPDGTVDGTRDRSDPHIQFQISPEG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Experimental support for the evolution of symmetric protein architecture from a simple peptide motif.
pubmed doi rcsb
molecule tags De novo protein
source organism Synthetic construct
molecule keywords de novo designed monomer trefoil-fold sub-domain which forms
total genus 5
structure length 43
sequence length 43
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2010-08-25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.260 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 3ol0A00
3OL0A
chains in the Genus database with same CATH superfamily
1KBEA 3TJQA 1FAQA 2DKVA 1K7VA 1LR7A 1TIHA 1WGCA 2ODDA 2RC4A 2WCYA 3KY9A 1WTJA 3TO6A 4WP4A 1PTQA 2ERWA 2V1CC 5HI7A 1KMAA 3UEJA 1V1HA 1R0RI 2KMRA 1HPTA 2OU2A 2NU2I 1FYBA 1UHAA 2GKRI 2N17A 3R5BA 5FUYA 2KCXA 1CGJI 2JA1A 2OZUA 4DNCA 5FUVA 3BJIA 3UGIA 1PCEA 1PJUA 2SGQI 1PPFI 1H0ZA 4AMLA 1OMTA 3QTLD 3QWPA 4A24A 3HH2C 2KMOA 3R5DA 3TOBA 1HDLA 2FNFX 2YQPA 1SGEI 2ARPF 5HQ8A 5J8FA 2GIVA 2OD1A 5CCMA 1CE3A 4UXIA 1IY5A 2K9HA 9WGAA 1M8BA 2ORWA 1W4RA 2Y0MA 2L7XA 1TBRR 3E59A 5EX0A 1Y8FA 1P9ZA 2X52A 3TOAA 1PTRA 1BMOA 2X3TA 1SGYI 1X4SA 2SGPI 4SGBI 5JHWC 1DS3I 1UVGA 1LR8A 1SGDI 1LR9A 4GI3C 2NU1I 2E5RA 2OVOA 7WGAA 4OVOA 1M8CA 3B4VC 1V1IA 4B6DA 2UZ3A 2JW6A 2B8TA 1YTPA 2DIPA 1MJ9A 2V53A 3UEYA 1OMUA 1RFHA 1S20A 4HGUA 2N71A 1FARA 1CSOI 1XBTA 3CXLA 3OL0A 1Y1BA 1Z7KB 3SEKC 1CHOI 2V1CA 1BUSA 2JYYA 2QPOA 3FSXA 3PDNA 4L9MA 1CT2I 3SGQI 3UOEA 1Y1CA 4FKDA 4E1RA 1SGQI 2P6AC 3VDPA 2VRWB 2BUSA 2KMQA 2ENZA 2J9RA 2SGFI 2JXDA 1ULMA 3VE5A 2W0TA 3TO9A 3FC3A 1Q9BA 1TBQR 2JZMA 4E1PA 2CWHA 5E3RA 2LEOA 1TURA 3SGBI 2QQ0A 1KBFA 2ELIA 3GOXA 3OVOA 1N13A 2A20A 1OYVI 3QAHA 3UGLA 5CCLA 1K7UA 2M5XA 3VDUA 1ULKA 2QQEA 2SGDI 1MT1A 2F3CI 1XA6A 1YU6C 2LB7A 1XX6A 1R79A 1CGII 3R5CA 2NU3I 2L8EA 1K7TA 2NU4I 1P9GA 2UVOA 3MEKA 1SGRI 3FSYA 1MJAA 1CT4I 1OVOA 1W3SA 1WGTA 1X74A 2B0UC 1TBOA 4UXJA 5DAEA 1CT0I 1VDDA 2XRCA 2NU0I 2PQ8A 1IW4A 2GKVA 1ULNA 1TBNA 3UGDA 1HEVA 2YUUA 1U5KA 2SGEI 3OXLA 4UXHA 1TUSA 2GKTI 1SGPI 2QQCA 2QQDA 2ORVA 3R5AA 4JCVE 2CWGA 2J87A 2KMPA 2N1AB 5FUWA 1UVFA 2N52A 2E73A 3UFFA 3RU0A 2GVIA 3OXGA 2RIJA 1NUBA 1WKXA 1TOTA 5E3PA 5EX3A 5J8CA 2DB6A 1FY7A 1AN1I 2WGCA 4MPIA 5FUXA 3TO7A 2ENNA 2ROWA 3D00A 1SGNI 2CWFA 1UUCA 1Z2IA 1HJAI 1DS2I 5E3QA 3OXFA 1MJBA 1IY6A 2CJSC 2WVJA 1NXUA 1TGSI 2LUYA 3E2IA
chains in the Genus database with same CATH topology
1KBEA 3TJQA 1FAQA 1LR7A 1TIHA 2ODDA 2WCYA 3KY9A 1PTQA 2ERWA 2V1CC 5HI7A 1KMAA 3UEJA 1V1HA 1R0RI 2KMRA 1HPTA 2NU2I 1FYBA 2N17A 2GKRI 5FUYA 2KCXA 1CGJI 2JA1A 5FUVA 3BJIA 3UGIA 1PCEA 1PJUA 2SGQI 1PPFI 1H0ZA 1OMTA 3QTLD 3QWPA 4A24A 3HH2C 2KMOA 1HDLA 2FNFX 2YQPA 1SGEI 2ARPF 5HQ8A 1CE3A 2OD1A 5CCMA 4UXIA 1IY5A 2K9HA 1M8BA 2ORWA 1W4RA 5EX0A 2L7XA 1TBRR 3E59A 1Y8FA 1PTRA 1BMOA 1SGYI 1X4SA 2SGPI 4SGBI 5JHWC 1DS3I 1UVGA 1LR8A 1SGDI 1LR9A 4GI3C 2NU1I 2E5RA 2OVOA 4OVOA 1M8CA 3B4VC 1V1IA 4B6DA 2UZ3A 2JW6A 2B8TA 1YTPA 2DIPA 2V53A 3UEYA 1OMUA 1RFHA 4HGUA 2N71A 1FARA 1CSOI 1XBTA 3CXLA 3OL0A 1Y1BA 1Z7KB 3SEKC 1CHOI 2V1CA 1BUSA 2JYYA 2QPOA 3SGQI 3PDNA 4L9MA 1CT2I 4E1RA 1Y1CA 4FKDA 1SGQI 2P6AC 3VDPA 2VRWB 2BUSA 2KMQA 2ENZA 2J9RA 2SGFI 2JXDA 3VE5A 2W0TA 3FC3A 1TBQR 2JZMA 4E1PA 2LEOA 1TURA 3SGBI 2QQ0A 1KBFA 2ELIA 3GOXA 3OVOA 1N13A 2A20A 1OYVI 3UGLA 5CCLA 2M5XA 3VDUA 2QQEA 2SGDI 1MT1A 2F3CI 1XA6A 1YU6C 1XX6A 1R79A 1CGII 2NU3I 2L8EA 2NU4I 3MEKA 1SGRI 4UXJA 1OVOA 1CT4I 1W3SA 1X74A 2B0UC 5DAEA 1TBOA 1CT0I 1VDDA 2XRCA 2NU0I 1IW4A 2GKVA 1TBNA 3UGDA 2YUUA 1U5KA 2SGEI 3OXLA 4UXHA 1TUSA 2GKTI 1SGPI 2QQCA 2QQDA 2ORVA 4JCVE 2J87A 2KMPA 5FUWA 2N1AB 1UVFA 2N52A 2E73A 3UFFA 3RU0A 2GVIA 3OXGA 1NUBA 1TOTA 5EX3A 2DB6A 1AN1I 5FUXA 2ENNA 2ROWA 3D00A 1SGNI 1UUCA 1HJAI 1DS2I 3OXFA 1IY6A 2CJSC 2WVJA 1TGSI 2LUYA 3E2IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OL0 A; 
#chains in the Genus database with same CATH topology
 1KBE A;  3TJQ A;  1FAQ A;  2DKV A;  1K7V A;  1LR7 A;  1TIH A;  1WGC A;  2ODD A;  2RC4 A;  2WCY A;  3KY9 A;  1WTJ A;  3TO6 A;  4WP4 A;  1PTQ A;  2ERW A;  2V1C C;  5HI7 A;  1KMA A;  3UEJ A;  1V1H A;  1R0R I;  2KMR A;  1HPT A;  2OU2 A;  2NU2 I;  1FYB A;  1UHA A;  2GKR I;  2N17 A;  3R5B A;  5FUY A;  2KCX A;  1CGJ I;  2JA1 A;  2OZU A;  4DNC A;  5FUV A;  3BJI A;  3UGI A;  1PCE A;  1PJU A;  2SGQ I;  1PPF I;  1H0Z A;  4AML A;  1OMT A;  3QTL D;  3QWP A;  4A24 A;  3HH2 C;  2KMO A;  3R5D A;  3TOB A;  1HDL A;  2FNF X;  2YQP A;  1SGE I;  2ARP F;  5HQ8 A;  5J8F A;  2GIV A;  2OD1 A;  5CCM A;  1CE3 A;  4UXI A;  1IY5 A;  2K9H A;  9WGA A;  1M8B A;  2ORW A;  1W4R A;  2Y0M A;  2L7X A;  1TBR R;  3E59 A;  5EX0 A;  1Y8F A;  1P9Z A;  2X52 A;  3TOA A;  1PTR A;  1BMO A;  2X3T A;  1SGY I;  1X4S A;  2SGP I;  4SGB I;  5JHW C;  1DS3 I;  1UVG A;  1LR8 A;  1SGD I;  1LR9 A;  4GI3 C;  2NU1 I;  2E5R A;  2OVO A;  7WGA A;  4OVO A;  1M8C A;  3B4V C;  1V1I A;  4B6D A;  2UZ3 A;  2JW6 A;  2B8T A;  1YTP A;  2DIP A;  1MJ9 A;  2V53 A;  3UEY A;  1OMU A;  1RFH A;  1S20 A;  4HGU A;  2N71 A;  1FAR A;  1CSO I;  1XBT A;  3CXL A;  3OL0 A;  1Y1B A;  1Z7K B;  3SEK C;  1CHO I;  2V1C A;  1BUS A;  2JYY A;  2QPO A;  3FSX A;  3PDN A;  4L9M A;  1CT2 I;  3SGQ I;  3UOE A;  1Y1C A;  4FKD A;  4E1R A;  1SGQ I;  2P6A C;  3VDP A;  2VRW B;  2BUS A;  2KMQ A;  2ENZ A;  2J9R A;  2SGF I;  2JXD A;  1ULM A;  3VE5 A;  2W0T A;  3TO9 A;  3FC3 A;  1Q9B A;  1TBQ R;  2JZM A;  4E1P A;  2CWH A;  5E3R A;  2LEO A;  1TUR A;  3SGB I;  2QQ0 A;  1KBF A;  2ELI A;  3GOX A;  3OVO A;  1N13 A;  2A20 A;  1OYV I;  3QAH A;  3UGL A;  5CCL A;  1K7U A;  2M5X A;  3VDU A;  1ULK A;  2QQE A;  2SGD I;  1MT1 A;  2F3C I;  1XA6 A;  1YU6 C;  2LB7 A;  1XX6 A;  1R79 A;  1CGI I;  3R5C A;  2NU3 I;  2L8E A;  1K7T A;  2NU4 I;  1P9G A;  2UVO A;  3MEK A;  1SGR I;  3FSY A;  1MJA A;  1CT4 I;  1OVO A;  1W3S A;  1WGT A;  1X74 A;  2B0U C;  1TBO A;  4UXJ A;  5DAE A;  1CT0 I;  1VDD A;  2XRC A;  2NU0 I;  2PQ8 A;  1IW4 A;  2GKV A;  1ULN A;  1TBN A;  3UGD A;  1HEV A;  2YUU A;  1U5K A;  2SGE I;  3OXL A;  4UXH A;  1TUS A;  2GKT I;  1SGP I;  2QQC A;  2QQD A;  2ORV A;  3R5A A;  4JCV E;  2CWG A;  2J87 A;  2KMP A;  2N1A B;  5FUW A;  1UVF A;  2N52 A;  2E73 A;  3UFF A;  3RU0 A;  2GVI A;  3OXG A;  2RIJ A;  1NUB A;  1WKX A;  1TOT A;  5E3P A;  5EX3 A;  5J8C A;  2DB6 A;  1FY7 A;  1AN1 I;  2WGC A;  4MPI A;  5FUX A;  3TO7 A;  2ENN A;  2ROW A;  3D00 A;  1SGN I;  2CWF A;  1UUC A;  1Z2I A;  1HJA I;  1DS2 I;  5E3Q A;  3OXF A;  1MJB A;  1IY6 A;  2CJS C;  2WVJ A;  1NXU A;  1TGS I;  2LUY A;  3E2I A; 
#chains in the Genus database with same CATH homology
 1KBE A;  3TJQ A;  1FAQ A;  1LR7 A;  1TIH A;  2ODD A;  2WCY A;  3KY9 A;  1PTQ A;  2ERW A;  2V1C C;  5HI7 A;  1KMA A;  3UEJ A;  1V1H A;  1R0R I;  2KMR A;  1HPT A;  2NU2 I;  1FYB A;  2N17 A;  2GKR I;  5FUY A;  2KCX A;  1CGJ I;  2JA1 A;  5FUV A;  3BJI A;  3UGI A;  1PCE A;  1PJU A;  2SGQ I;  1PPF I;  1H0Z A;  1OMT A;  3QTL D;  3QWP A;  4A24 A;  3HH2 C;  2KMO A;  1HDL A;  2FNF X;  2YQP A;  1SGE I;  2ARP F;  5HQ8 A;  1CE3 A;  2OD1 A;  5CCM A;  4UXI A;  1IY5 A;  2K9H A;  1M8B A;  2ORW A;  1W4R A;  5EX0 A;  2L7X A;  1TBR R;  3E59 A;  1Y8F A;  1PTR A;  1BMO A;  1SGY I;  1X4S A;  2SGP I;  4SGB I;  5JHW C;  1DS3 I;  1UVG A;  1LR8 A;  1SGD I;  1LR9 A;  4GI3 C;  2NU1 I;  2E5R A;  2OVO A;  4OVO A;  1M8C A;  3B4V C;  1V1I A;  4B6D A;  2UZ3 A;  2JW6 A;  2B8T A;  1YTP A;  2DIP A;  2V53 A;  3UEY A;  1OMU A;  1RFH A;  4HGU A;  2N71 A;  1FAR A;  1CSO I;  1XBT A;  3CXL A;  3OL0 A;  1Y1B A;  1Z7K B;  3SEK C;  1CHO I;  2V1C A;  1BUS A;  2JYY A;  2QPO A;  3SGQ I;  3PDN A;  4L9M A;  1CT2 I;  4E1R A;  1Y1C A;  4FKD A;  1SGQ I;  2P6A C;  3VDP A;  2VRW B;  2BUS A;  2KMQ A;  2ENZ A;  2J9R A;  2SGF I;  2JXD A;  3VE5 A;  2W0T A;  3FC3 A;  1TBQ R;  2JZM A;  4E1P A;  2LEO A;  1TUR A;  3SGB I;  2QQ0 A;  1KBF A;  2ELI A;  3GOX A;  3OVO A;  1N13 A;  2A20 A;  1OYV I;  3UGL A;  5CCL A;  2M5X A;  3VDU A;  2QQE A;  2SGD I;  1MT1 A;  2F3C I;  1XA6 A;  1YU6 C;  1XX6 A;  1R79 A;  1CGI I;  2NU3 I;  2L8E A;  2NU4 I;  3MEK A;  1SGR I;  4UXJ A;  1OVO A;  1CT4 I;  1W3S A;  1X74 A;  2B0U C;  5DAE A;  1TBO A;  1CT0 I;  1VDD A;  2XRC A;  2NU0 I;  1IW4 A;  2GKV A;  1TBN A;  3UGD A;  2YUU A;  1U5K A;  2SGE I;  3OXL A;  4UXH A;  1TUS A;  2GKT I;  1SGP I;  2QQC A;  2QQD A;  2ORV A;  4JCV E;  2J87 A;  2KMP A;  5FUW A;  2N1A B;  1UVF A;  2N52 A;  2E73 A;  3UFF A;  3RU0 A;  2GVI A;  3OXG A;  1NUB A;  1TOT A;  5EX3 A;  2DB6 A;  1AN1 I;  5FUX A;  2ENN A;  2ROW A;  3D00 A;  1SGN I;  1UUC A;  1HJA I;  1DS2 I;  3OXF A;  1IY6 A;  2CJS C;  2WVJ A;  1TGS I;  2LUY A;  3E2I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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