3UEYA

Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase cdelta
Total Genus 10
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
65
structure length
65
Chain Sequence
GSRRASVGSHRFKVFNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCEFIVTD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta
pubmed doi rcsb
molecule tags Metal binding protein
source organism Mus musculus
molecule keywords Protein kinase C delta type
total genus 10
structure length 65
sequence length 65
chains with identical sequence B
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2011-10-31
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.20 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 3ueyA01
2J9RA 1W4RA 2YUUA 3BJIA 3UEJA 2QQEA 2ENZA 1FARA 1TBOA 2ROWA 2QQ0A 2QPOA 4B6DA 1KBFA 2ORVA 2ENNA 1RFHA 2VRWB 3E2IA 4UXJA 1R79A 4UXHA 5FUWA 5FUXA 3UGDA 3CXLA 5FUYA 2ELIA 2GVIA 2WVJA 2UZ3A 1XBTA 1KBEA 2JA1A 4L9MA 3UFFA 4FKDA 3UGIA 2E73A 3UEYA 3KY9A 2ORWA 5FUVA 1XX6A 1Y8FA 2DB6A 1TBNA 1PTRA 2J87A 2FNFX 4UXIA 1XA6A 3UGLA 2B8TA 1PTQA 1FAQA
chains in the Genus database with same CATH superfamily
1DS3I 2SGFI 3TJQA 2GKTI 2SGQI 1PJUA 1TBOA 1Y1BA 1V1HA 1MJAA 1ULNA 3VDUA 2CWHA 3R5BA 3OL0A 3SGQI 2ENNA 2V1CC 1YU6C 3PDNA 2A20A 2RC4A 4UXJA 1X4SA 2ARPF 5CCMA 1IW4A 2XRCA 2X52A 3B4VC 1K7TA 1SGQI 2JA1A 2WCYA 3UGIA 2WGCA 1P9GA 2M5XA 9WGAA 4DNCA 3KY9A 1CT4I 1X74A 1PPFI 1XX6A 2KMPA 2LEOA 5EX3A 1LR8A 2KMRA 1M8BA 1SGEI 2OU2A 3QTLD 1ULKA 1ULMA 1KMAA 2NU3I 1SGRI 2SGPI 1HPTA 2GKRI 2V1CA 2L7XA 3R5AA 1IY5A 1OVOA 3GOXA 1MJBA 2F3CI 5DAEA 2JW6A 4SGBI 1Z2IA 2GKVA 4E1PA 1W4RA 2PQ8A 1CHOI 2QQEA 4HGUA 1TGSI 1AN1I 3VDPA 2QPOA 2JXDA 4GI3C 2NU4I 2NU2I 1WGCA 2E5RA 2ORVA 5E3RA 4B6DA 1KBFA 1S20A 1Z7KB 2X3TA 2N52A 2KMQA 4UXHA 1SGNI 1Y1CA 2DIPA 3UGDA 3R5DA 2B0UC 1TBRR 3FC3A 2GVIA 5JHWC 5HI7A 2SGDI 2CWGA 1CE3A 2OZUA 1LR7A 1K7VA 2CWFA 3UEYA 2DKVA 1CT2I 2ORWA 2QQCA 5FUVA 1V1IA 1NXUA 1W3SA 1YTPA 2CJSC 2JYYA 2NU0I 2RIJA 3D00A 1VDDA 3HH2C 3SEKC 4AMLA 5J8FA 2ERWA 4UXIA 1DS2I 2V53A 3R5CA 5J8CA 1SGPI 2B8TA 1PTQA 1TURA 3QWPA 2J9RA 2SGEI 3OXGA 3SGBI 1TIHA 2ODDA 1HEVA 1K7UA 2QQDA 1FARA 2LB7A 2ROWA 2QQ0A 1FY7A 1SGYI 1HJAI 1BMOA 1UVFA 2VRWB 1RFHA 2W0TA 3E2IA 1TBQR 3E59A 1R79A 3UOEA 5FUWA 1H0ZA 2OVOA 1N13A 1R0RI 5FUYA 2ELIA 2WVJA 3VE5A 1P9ZA 1NUBA 3UFFA 1XBTA 1CGJI 1TUSA 1U5KA 2JZMA 1OYVI 2E73A 3OVOA 1TBNA 1FYBA 1UUCA 1M8CA 2L8EA 1CGII 2NU1I 2FNFX 2YQPA 7WGAA 1XA6A 3UGLA 1HDLA 2GIVA 1IY6A 1LR9A 1WKXA 3TO6A 2KCXA 2P6AC 5HQ8A 4WP4A 4A24A 2N71A 1OMUA 2UVOA 2YUUA 3BJIA 3RU0A 3UEJA 2ENZA 2BUSA 3TO9A 2KMOA 1CT0I 5CCLA 2LUYA 5FUXA 3TOAA 2N17A 3CXLA 1CSOI 3TOBA 1Q9BA 2OD1A 1SGDI 3MEKA 5E3PA 2N1AB 2UZ3A 4JCVE 1KBEA 4L9MA 1PCEA 1TOTA 4MPIA 1UVGA 4FKDA 5EX0A 4E1RA 1WGTA 5E3QA 4OVOA 1WTJA 1Y8FA 2DB6A 3TO7A 1PTRA 3FSXA 2J87A 1UHAA 3OXLA 3OXFA 2K9HA 1MT1A 3QAHA 1MJ9A 1OMTA 3FSYA 1BUSA 1FAQA 2Y0MA
chains in the Genus database with same CATH topology
1DS3I 2SGFI 3TJQA 2GKTI 2SGQI 1PJUA 1TBOA 1Y1BA 1V1HA 3VDUA 3SGQI 3OL0A 3FC3A 2ENNA 2V1CC 1YU6C 3PDNA 2A20A 4UXJA 5CCMA 1X4SA 2ARPF 1IW4A 2XRCA 3B4VC 1SGQI 2JA1A 2WCYA 3UGIA 2M5XA 3KY9A 1CT4I 1X74A 1PPFI 1XX6A 2KMPA 2LEOA 5EX3A 1LR8A 2KMRA 1M8BA 1SGEI 3QTLD 1KMAA 2NU3I 1SGRI 2SGPI 1HPTA 2GKRI 2V1CA 2L7XA 1IY5A 1OVOA 3GOXA 5DAEA 2F3CI 2JW6A 4SGBI 2GKVA 4E1PA 1W4RA 1CHOI 2QQEA 4HGUA 1TGSI 1AN1I 3VDPA 2QPOA 2JXDA 4GI3C 2NU4I 2NU2I 2ORVA 2E5RA 4B6DA 1KBFA 1Z7KB 2N52A 2KMQA 4UXHA 1SGNI 1Y1CA 2DIPA 3UGDA 2B0UC 1TBRR 2GVIA 5JHWC 5HI7A 2SGDI 1CE3A 1LR7A 3UEYA 1CT2I 2ORWA 2QQCA 5FUVA 1V1IA 1W3SA 1YTPA 2CJSC 2JYYA 2NU0I 3D00A 3HH2C 1VDDA 3SEKC 2ERWA 4UXIA 1DS2I 2V53A 2B8TA 1SGPI 1PTQA 1TURA 3QWPA 2J9RA 2SGEI 3OXGA 3SGBI 1TIHA 2ODDA 2QQDA 1FARA 2ROWA 2QQ0A 1SGYI 1HJAI 1BMOA 1UVFA 2VRWB 1RFHA 2W0TA 3E2IA 1TBQR 3E59A 1R79A 5FUWA 1H0ZA 2OVOA 1N13A 1R0RI 5FUYA 2ELIA 2WVJA 3VE5A 1NUBA 3UFFA 1XBTA 1CGJI 1TUSA 1U5KA 2JZMA 1OYVI 2E73A 3OVOA 1TBNA 1FYBA 1UUCA 1M8CA 2L8EA 1CGII 2NU1I 2FNFX 2YQPA 1XA6A 3UGLA 1HDLA 1IY6A 1LR9A 2KCXA 2P6AC 5HQ8A 4A24A 2N71A 1OMUA 2YUUA 3BJIA 3RU0A 3UEJA 2ENZA 2BUSA 2KMOA 1CT0I 5CCLA 2LUYA 5FUXA 2N17A 3CXLA 1CSOI 2OD1A 1SGDI 3MEKA 2N1AB 2UZ3A 4JCVE 1KBEA 4L9MA 1PCEA 1TOTA 5EX0A 1UVGA 4FKDA 4E1RA 4OVOA 1Y8FA 2DB6A 1PTRA 3OXLA 2J87A 3OXFA 2K9HA 1MT1A 1OMTA 1BUSA 1FAQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J9R A;  1W4R A;  2YUU A;  3BJI A;  3UEJ A;  2QQE A;  2ENZ A;  1FAR A;  1TBO A;  2ROW A;  2QQ0 A;  2QPO A;  4B6D A;  1KBF A;  2ORV A;  2ENN A;  1RFH A;  2VRW B;  3E2I A;  4UXJ A;  1R79 A;  4UXH A;  5FUW A;  5FUX A;  3UGD A;  3CXL A;  5FUY A;  2ELI A;  2GVI A;  2WVJ A;  2UZ3 A;  1XBT A;  1KBE A;  2JA1 A;  4L9M A;  3UFF A;  4FKD A;  3UGI A;  2E73 A;  3UEY A;  3KY9 A;  2ORW A;  5FUV A;  1XX6 A;  1Y8F A;  2DB6 A;  1TBN A;  1PTR A;  2J87 A;  2FNF X;  4UXI A;  1XA6 A;  3UGL A;  2B8T A;  1PTQ A;  1FAQ A; 
#chains in the Genus database with same CATH topology
 1DS3 I;  2SGF I;  3TJQ A;  2GKT I;  2SGQ I;  1PJU A;  1TBO A;  1Y1B A;  1V1H A;  1MJA A;  1ULN A;  3VDU A;  2CWH A;  3R5B A;  3OL0 A;  3SGQ I;  2ENN A;  2V1C C;  1YU6 C;  3PDN A;  2A20 A;  2RC4 A;  4UXJ A;  1X4S A;  2ARP F;  5CCM A;  1IW4 A;  2XRC A;  2X52 A;  3B4V C;  1K7T A;  1SGQ I;  2JA1 A;  2WCY A;  3UGI A;  2WGC A;  1P9G A;  2M5X A;  9WGA A;  4DNC A;  3KY9 A;  1CT4 I;  1X74 A;  1PPF I;  1XX6 A;  2KMP A;  2LEO A;  5EX3 A;  1LR8 A;  2KMR A;  1M8B A;  1SGE I;  2OU2 A;  3QTL D;  1ULK A;  1ULM A;  1KMA A;  2NU3 I;  1SGR I;  2SGP I;  1HPT A;  2GKR I;  2V1C A;  2L7X A;  3R5A A;  1IY5 A;  1OVO A;  3GOX A;  1MJB A;  2F3C I;  5DAE A;  2JW6 A;  4SGB I;  1Z2I A;  2GKV A;  4E1P A;  1W4R A;  2PQ8 A;  1CHO I;  2QQE A;  4HGU A;  1TGS I;  1AN1 I;  3VDP A;  2QPO A;  2JXD A;  4GI3 C;  2NU4 I;  2NU2 I;  1WGC A;  2E5R A;  2ORV A;  5E3R A;  4B6D A;  1KBF A;  1S20 A;  1Z7K B;  2X3T A;  2N52 A;  2KMQ A;  4UXH A;  1SGN I;  1Y1C A;  2DIP A;  3UGD A;  3R5D A;  2B0U C;  1TBR R;  3FC3 A;  2GVI A;  5JHW C;  5HI7 A;  2SGD I;  2CWG A;  1CE3 A;  2OZU A;  1LR7 A;  1K7V A;  2CWF A;  3UEY A;  2DKV A;  1CT2 I;  2ORW A;  2QQC A;  5FUV A;  1V1I A;  1NXU A;  1W3S A;  1YTP A;  2CJS C;  2JYY A;  2NU0 I;  2RIJ A;  3D00 A;  1VDD A;  3HH2 C;  3SEK C;  4AML A;  5J8F A;  2ERW A;  4UXI A;  1DS2 I;  2V53 A;  3R5C A;  5J8C A;  1SGP I;  2B8T A;  1PTQ A;  1TUR A;  3QWP A;  2J9R A;  2SGE I;  3OXG A;  3SGB I;  1TIH A;  2ODD A;  1HEV A;  1K7U A;  2QQD A;  1FAR A;  2LB7 A;  2ROW A;  2QQ0 A;  1FY7 A;  1SGY I;  1HJA I;  1BMO A;  1UVF A;  2VRW B;  1RFH A;  2W0T A;  3E2I A;  1TBQ R;  3E59 A;  1R79 A;  3UOE A;  5FUW A;  1H0Z A;  2OVO A;  1N13 A;  1R0R I;  5FUY A;  2ELI A;  2WVJ A;  3VE5 A;  1P9Z A;  1NUB A;  3UFF A;  1XBT A;  1CGJ I;  1TUS A;  1U5K A;  2JZM A;  1OYV I;  2E73 A;  3OVO A;  1TBN A;  1FYB A;  1UUC A;  1M8C A;  2L8E A;  1CGI I;  2NU1 I;  2FNF X;  2YQP A;  7WGA A;  1XA6 A;  3UGL A;  1HDL A;  2GIV A;  1IY6 A;  1LR9 A;  1WKX A;  3TO6 A;  2KCX A;  2P6A C;  5HQ8 A;  4WP4 A;  4A24 A;  2N71 A;  1OMU A;  2UVO A;  2YUU A;  3BJI A;  3RU0 A;  3UEJ A;  2ENZ A;  2BUS A;  3TO9 A;  2KMO A;  1CT0 I;  5CCL A;  2LUY A;  5FUX A;  3TOA A;  2N17 A;  3CXL A;  1CSO I;  3TOB A;  1Q9B A;  2OD1 A;  1SGD I;  3MEK A;  5E3P A;  2N1A B;  2UZ3 A;  4JCV E;  1KBE A;  4L9M A;  1PCE A;  1TOT A;  4MPI A;  1UVG A;  4FKD A;  5EX0 A;  4E1R A;  1WGT A;  5E3Q A;  4OVO A;  1WTJ A;  1Y8F A;  2DB6 A;  3TO7 A;  1PTR A;  3FSX A;  2J87 A;  1UHA A;  3OXL A;  3OXF A;  2K9H A;  1MT1 A;  3QAH A;  1MJ9 A;  1OMT A;  3FSY A;  1BUS A;  1FAQ A;  2Y0M A; 
#chains in the Genus database with same CATH homology
 1DS3 I;  2SGF I;  3TJQ A;  2GKT I;  2SGQ I;  1PJU A;  1TBO A;  1Y1B A;  1V1H A;  3VDU A;  3SGQ I;  3OL0 A;  3FC3 A;  2ENN A;  2V1C C;  1YU6 C;  3PDN A;  2A20 A;  4UXJ A;  5CCM A;  1X4S A;  2ARP F;  1IW4 A;  2XRC A;  3B4V C;  1SGQ I;  2JA1 A;  2WCY A;  3UGI A;  2M5X A;  3KY9 A;  1CT4 I;  1X74 A;  1PPF I;  1XX6 A;  2KMP A;  2LEO A;  5EX3 A;  1LR8 A;  2KMR A;  1M8B A;  1SGE I;  3QTL D;  1KMA A;  2NU3 I;  1SGR I;  2SGP I;  1HPT A;  2GKR I;  2V1C A;  2L7X A;  1IY5 A;  1OVO A;  3GOX A;  5DAE A;  2F3C I;  2JW6 A;  4SGB I;  2GKV A;  4E1P A;  1W4R A;  1CHO I;  2QQE A;  4HGU A;  1TGS I;  1AN1 I;  3VDP A;  2QPO A;  2JXD A;  4GI3 C;  2NU4 I;  2NU2 I;  2ORV A;  2E5R A;  4B6D A;  1KBF A;  1Z7K B;  2N52 A;  2KMQ A;  4UXH A;  1SGN I;  1Y1C A;  2DIP A;  3UGD A;  2B0U C;  1TBR R;  2GVI A;  5JHW C;  5HI7 A;  2SGD I;  1CE3 A;  1LR7 A;  3UEY A;  1CT2 I;  2ORW A;  2QQC A;  5FUV A;  1V1I A;  1W3S A;  1YTP A;  2CJS C;  2JYY A;  2NU0 I;  3D00 A;  3HH2 C;  1VDD A;  3SEK C;  2ERW A;  4UXI A;  1DS2 I;  2V53 A;  2B8T A;  1SGP I;  1PTQ A;  1TUR A;  3QWP A;  2J9R A;  2SGE I;  3OXG A;  3SGB I;  1TIH A;  2ODD A;  2QQD A;  1FAR A;  2ROW A;  2QQ0 A;  1SGY I;  1HJA I;  1BMO A;  1UVF A;  2VRW B;  1RFH A;  2W0T A;  3E2I A;  1TBQ R;  3E59 A;  1R79 A;  5FUW A;  1H0Z A;  2OVO A;  1N13 A;  1R0R I;  5FUY A;  2ELI A;  2WVJ A;  3VE5 A;  1NUB A;  3UFF A;  1XBT A;  1CGJ I;  1TUS A;  1U5K A;  2JZM A;  1OYV I;  2E73 A;  3OVO A;  1TBN A;  1FYB A;  1UUC A;  1M8C A;  2L8E A;  1CGI I;  2NU1 I;  2FNF X;  2YQP A;  1XA6 A;  3UGL A;  1HDL A;  1IY6 A;  1LR9 A;  2KCX A;  2P6A C;  5HQ8 A;  4A24 A;  2N71 A;  1OMU A;  2YUU A;  3BJI A;  3RU0 A;  3UEJ A;  2ENZ A;  2BUS A;  2KMO A;  1CT0 I;  5CCL A;  2LUY A;  5FUX A;  2N17 A;  3CXL A;  1CSO I;  2OD1 A;  1SGD I;  3MEK A;  2N1A B;  2UZ3 A;  4JCV E;  1KBE A;  4L9M A;  1PCE A;  1TOT A;  5EX0 A;  1UVG A;  4FKD A;  4E1R A;  4OVO A;  1Y8F A;  2DB6 A;  1PTR A;  3OXL A;  2J87 A;  3OXF A;  2K9H A;  1MT1 A;  1OMT A;  1BUS A;  1FAQ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...