3UEYA

Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase cdelta
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
65
structure length
65
Chain Sequence
GSRRASVGSHRFKVFNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCEFIVTD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta
pubmed doi rcsb
molecule tags Metal binding protein
source organism Mus musculus
molecule keywords Protein kinase C delta type
total genus 10
structure length 65
sequence length 65
chains with identical sequence B
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2011-10-31
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.20 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 3ueyA01
2DB6A 5FUXA 3KY9A 2FNFX 4UXHA 3E2IA 1KBFA 1PTRA 2ELIA 3UEJA 1R79A 2QPOA 3UGLA 1Y8FA 2J87A 2B8TA 5FUYA 4B6DA 2ROWA 3CXLA 4UXIA 2ORWA 4FKDA 1TBNA 4UXJA 1XBTA 3UGIA 2ENZA 2GVIA 2UZ3A 5FUWA 4L9MA 1FARA 5FUVA 3UEYA 1FAQA 2ORVA 2QQ0A 1RFHA 1TBOA 2E73A 2ENNA 2J9RA 3UGDA 2QQEA 1PTQA 1XA6A 2JA1A 2VRWB 3UFFA 1KBEA 1W4RA 3BJIA 1XX6A 2WVJA 2YUUA
chains in the Genus database with same CATH superfamily
3R5AA 2DB6A 3TO6A 1OYVI 1CT2I 2B0UC 1WTJA 2F3CI 1V1IA 2QQDA 5EX3A 7WGAA 1K7VA 2JXDA 3VDPA 3TO9A 2SGQI 9WGAA 3UGLA 3R5BA 1PJUA 2B8TA 5J8CA 2ROWA 1TBRR 1CGII 1LR8A 1BMOA 2K9HA 3PDNA 2GIVA 4FKDA 5E3QA 2JZMA 2DKVA 2LUYA 2JW6A 2UZ3A 2N17A 1SGRI 2V1CA 3UEYA 2RC4A 2ERWA 2QQ0A 1OMTA 1X74A 1Y1BA 3UGDA 1UVGA 3MEKA 1UUCA 1MJBA 1HJAI 3RU0A 2NU4I 5E3PA 1TURA 5FUVA 4E1RA 1FY7A 1NXUA 1ULNA 1K7UA 3KY9A 2FNFX 4UXHA 5FUXA 5EX0A 3TO7A 1KBFA 1PCEA 2ELIA 1OVOA 3TJQA 1R79A 2V53A 2WCYA 1U5KA 1Y8FA 2X3TA 2CWHA 1CT4I 1X4SA 3CXLA 3OXFA 3SGQI 4UXIA 2NU0I 1CSOI 3VDUA 1WGTA 1LR9A 1P9GA 1XBTA 4UXJA 1KMAA 1ULMA 2GVIA 3R5CA 2PQ8A 2GKTI 5FUWA 1HEVA 1P9ZA 2L7XA 4L9MA 1FARA 1LR7A 2ORVA 1RFHA 2V1CC 2A20A 3OXGA 1ULKA 2GKRI 4WP4A 1H0ZA 4SGBI 4AMLA 2P6AC 1Y1CA 2L8EA 2J9RA 5CCLA 2QQEA 1S20A 1SGDI 2VRWB 3UFFA 4DNCA 1TOTA 3BJIA 1XX6A 1MJAA 1Q9BA 2KMRA 1UVFA 2ARPF 1CE3A 4HGUA 2N1AB 1SGPI 1N13A 1TBQR 2KMQA 1Z7KB 3UEJA 2OVOA 1DS2I 3QAHA 3VE5A 2RIJA 2M5XA 1M8CA 1M8BA 2J87A 3QTLD 1AN1I 1TIHA 5HQ8A 1IW4A 2KMOA 3R5DA 1MJ9A 2X52A 4JCVE 4MPIA 2ORWA 2NU2I 2BUSA 2ODDA 3FSYA 2SGFI 2OU2A 3B4VC 1TBNA 4GI3C 5E3RA 1SGNI 2NU1I 3UGIA 2YQPA 3SGBI 1PPFI 2W0TA 2UVOA 2OZUA 2OD1A 2Y0MA 1YU6C 2E73A 1SGQI 1NUBA 3HH2C 1XA6A 2JA1A 2WGCA 3GOXA 1IY5A 1TUSA 2JYYA 1W4RA 1Z2IA 2NU3I 1R0RI 2WVJA 1YTPA 2SGEI 1WGCA 3OXLA 1K7TA 5HI7A 2SGDI 3OVOA 2LEOA 2CWGA 3E2IA 3UOEA 2N52A 1PTRA 2XRCA 2SGPI 2N71A 2KCXA 2QPOA 3QWPA 2CWFA 3D00A 3FC3A 1BUSA 3TOAA 3OL0A 1W3SA 5FUYA 4B6DA 4OVOA 1CHOI 5JHWC 2GKVA 1FYBA 1IY6A 5CCMA 1V1HA 1OMUA 1HDLA 5J8FA 1SGEI 2ENZA 1CGJI 1DS3I 2QQCA 2CJSC 3TOBA 2E5RA 1FAQA 1TBOA 1WKXA 1SGYI 2LB7A 1UHAA 2ENNA 1VDDA 3SEKC 1MT1A 1HPTA 4E1PA 1PTQA 1CT0I 2DIPA 3E59A 1KBEA 1TGSI 4A24A 3FSXA 5DAEA 2YUUA 2KMPA
chains in the Genus database with same CATH topology
2DB6A 1OYVI 1CT2I 2B0UC 5EX3A 2F3CI 1V1IA 2QQDA 3VDPA 2JXDA 2SGQI 3UGLA 1PJUA 2B8TA 2ROWA 1TBRR 1CGII 1LR8A 1BMOA 2K9HA 3PDNA 4FKDA 2JZMA 2LUYA 2JW6A 2UZ3A 2N17A 1SGRI 2V1CA 3UEYA 2ERWA 2QQ0A 1OMTA 1X74A 1Y1BA 3UGDA 1UVGA 3MEKA 1UUCA 1HJAI 3RU0A 2NU4I 1TURA 5FUVA 4E1RA 5FUXA 3KY9A 2FNFX 4UXHA 5EX0A 1KBFA 1PCEA 2ELIA 1OVOA 3TJQA 1R79A 2V53A 2WCYA 1U5KA 1Y8FA 1CT4I 1X4SA 3CXLA 3OXFA 3SGQI 4UXIA 2NU0I 1CSOI 3VDUA 1LR9A 4UXJA 1XBTA 1KMAA 2GVIA 2GKTI 5FUWA 4L9MA 2L7XA 1FARA 1LR7A 2ORVA 1RFHA 2V1CC 2A20A 3OXGA 2GKRI 1H0ZA 4SGBI 2P6AC 1Y1CA 2L8EA 2J9RA 5CCLA 2QQEA 1SGDI 2VRWB 3UFFA 1TOTA 3BJIA 1XX6A 2KMRA 1UVFA 2ARPF 1CE3A 4HGUA 2N1AB 1SGPI 1N13A 1TBQR 2KMQA 1Z7KB 3UEJA 2OVOA 1DS2I 3VE5A 2M5XA 1M8CA 1M8BA 2J87A 3QTLD 1AN1I 1TIHA 5HQ8A 1IW4A 2KMOA 4JCVE 2ORWA 2NU2I 2BUSA 2ODDA 2SGFI 4GI3C 3B4VC 1TBNA 1SGNI 2NU1I 3UGIA 2YQPA 3SGBI 1PPFI 2W0TA 2OD1A 1YU6C 2E73A 1SGQI 1NUBA 3HH2C 1XA6A 2JA1A 3GOXA 1IY5A 1TUSA 2JYYA 1W4RA 2NU3I 1R0RI 2WVJA 1YTPA 2SGEI 3OXLA 5HI7A 2SGDI 3OVOA 2LEOA 3E2IA 2N52A 1PTRA 2XRCA 2SGPI 2N71A 2KCXA 2QPOA 3QWPA 3FC3A 3D00A 1BUSA 1IY6A 3OL0A 1W3SA 5FUYA 4B6DA 4OVOA 1CHOI 5JHWC 2GKVA 1FYBA 5CCMA 1V1HA 1OMUA 1HDLA 1SGEI 2ENZA 1CGJI 1DS3I 2QQCA 2CJSC 2E5RA 1FAQA 1TBOA 1SGYI 2ENNA 1VDDA 3SEKC 1MT1A 1HPTA 4E1PA 1PTQA 1CT0I 2DIPA 3E59A 1KBEA 1TGSI 4A24A 5DAEA 2YUUA 2KMPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DB6 A;  5FUX A;  3KY9 A;  2FNF X;  4UXH A;  3E2I A;  1KBF A;  1PTR A;  2ELI A;  3UEJ A;  1R79 A;  2QPO A;  3UGL A;  1Y8F A;  2J87 A;  2B8T A;  5FUY A;  4B6D A;  2ROW A;  3CXL A;  4UXI A;  2ORW A;  4FKD A;  1TBN A;  4UXJ A;  1XBT A;  3UGI A;  2ENZ A;  2GVI A;  2UZ3 A;  5FUW A;  4L9M A;  1FAR A;  5FUV A;  3UEY A;  1FAQ A;  2ORV A;  2QQ0 A;  1RFH A;  1TBO A;  2E73 A;  2ENN A;  2J9R A;  3UGD A;  2QQE A;  1PTQ A;  1XA6 A;  2JA1 A;  2VRW B;  3UFF A;  1KBE A;  1W4R A;  3BJI A;  1XX6 A;  2WVJ A;  2YUU A; 
#chains in the Genus database with same CATH topology
 3R5A A;  2DB6 A;  3TO6 A;  1OYV I;  1CT2 I;  2B0U C;  1WTJ A;  2F3C I;  1V1I A;  2QQD A;  5EX3 A;  7WGA A;  1K7V A;  2JXD A;  3VDP A;  3TO9 A;  2SGQ I;  9WGA A;  3UGL A;  3R5B A;  1PJU A;  2B8T A;  5J8C A;  2ROW A;  1TBR R;  1CGI I;  1LR8 A;  1BMO A;  2K9H A;  3PDN A;  2GIV A;  4FKD A;  5E3Q A;  2JZM A;  2DKV A;  2LUY A;  2JW6 A;  2UZ3 A;  2N17 A;  1SGR I;  2V1C A;  3UEY A;  2RC4 A;  2ERW A;  2QQ0 A;  1OMT A;  1X74 A;  1Y1B A;  3UGD A;  1UVG A;  3MEK A;  1UUC A;  1MJB A;  1HJA I;  3RU0 A;  2NU4 I;  5E3P A;  1TUR A;  5FUV A;  4E1R A;  1FY7 A;  1NXU A;  1ULN A;  1K7U A;  3KY9 A;  2FNF X;  4UXH A;  5FUX A;  5EX0 A;  3TO7 A;  1KBF A;  1PCE A;  2ELI A;  1OVO A;  3TJQ A;  1R79 A;  2V53 A;  2WCY A;  1U5K A;  1Y8F A;  2X3T A;  2CWH A;  1CT4 I;  1X4S A;  3CXL A;  3OXF A;  3SGQ I;  4UXI A;  2NU0 I;  1CSO I;  3VDU A;  1WGT A;  1LR9 A;  1P9G A;  1XBT A;  4UXJ A;  1KMA A;  1ULM A;  2GVI A;  3R5C A;  2PQ8 A;  2GKT I;  5FUW A;  1HEV A;  1P9Z A;  2L7X A;  4L9M A;  1FAR A;  1LR7 A;  2ORV A;  1RFH A;  2V1C C;  2A20 A;  3OXG A;  1ULK A;  2GKR I;  4WP4 A;  1H0Z A;  4SGB I;  4AML A;  2P6A C;  1Y1C A;  2L8E A;  2J9R A;  5CCL A;  2QQE A;  1S20 A;  1SGD I;  2VRW B;  3UFF A;  4DNC A;  1TOT A;  3BJI A;  1XX6 A;  1MJA A;  1Q9B A;  2KMR A;  1UVF A;  2ARP F;  1CE3 A;  4HGU A;  2N1A B;  1SGP I;  1N13 A;  1TBQ R;  2KMQ A;  1Z7K B;  3UEJ A;  2OVO A;  1DS2 I;  3QAH A;  3VE5 A;  2RIJ A;  2M5X A;  1M8C A;  1M8B A;  2J87 A;  3QTL D;  1AN1 I;  1TIH A;  5HQ8 A;  1IW4 A;  2KMO A;  3R5D A;  1MJ9 A;  2X52 A;  4JCV E;  4MPI A;  2ORW A;  2NU2 I;  2BUS A;  2ODD A;  3FSY A;  2SGF I;  2OU2 A;  3B4V C;  1TBN A;  4GI3 C;  5E3R A;  1SGN I;  2NU1 I;  3UGI A;  2YQP A;  3SGB I;  1PPF I;  2W0T A;  2UVO A;  2OZU A;  2OD1 A;  2Y0M A;  1YU6 C;  2E73 A;  1SGQ I;  1NUB A;  3HH2 C;  1XA6 A;  2JA1 A;  2WGC A;  3GOX A;  1IY5 A;  1TUS A;  2JYY A;  1W4R A;  1Z2I A;  2NU3 I;  1R0R I;  2WVJ A;  1YTP A;  2SGE I;  1WGC A;  3OXL A;  1K7T A;  5HI7 A;  2SGD I;  3OVO A;  2LEO A;  2CWG A;  3E2I A;  3UOE A;  2N52 A;  1PTR A;  2XRC A;  2SGP I;  2N71 A;  2KCX A;  2QPO A;  3QWP A;  2CWF A;  3D00 A;  3FC3 A;  1BUS A;  3TOA A;  3OL0 A;  1W3S A;  5FUY A;  4B6D A;  4OVO A;  1CHO I;  5JHW C;  2GKV A;  1FYB A;  1IY6 A;  5CCM A;  1V1H A;  1OMU A;  1HDL A;  5J8F A;  1SGE I;  2ENZ A;  1CGJ I;  1DS3 I;  2QQC A;  2CJS C;  3TOB A;  2E5R A;  1FAQ A;  1TBO A;  1WKX A;  1SGY I;  2LB7 A;  1UHA A;  2ENN A;  1VDD A;  3SEK C;  1MT1 A;  1HPT A;  4E1P A;  1PTQ A;  1CT0 I;  2DIP A;  3E59 A;  1KBE A;  1TGS I;  4A24 A;  3FSX A;  5DAE A;  2YUU A;  2KMP A; 
#chains in the Genus database with same CATH homology
 2DB6 A;  1OYV I;  1CT2 I;  2B0U C;  5EX3 A;  2F3C I;  1V1I A;  2QQD A;  3VDP A;  2JXD A;  2SGQ I;  3UGL A;  1PJU A;  2B8T A;  2ROW A;  1TBR R;  1CGI I;  1LR8 A;  1BMO A;  2K9H A;  3PDN A;  4FKD A;  2JZM A;  2LUY A;  2JW6 A;  2UZ3 A;  2N17 A;  1SGR I;  2V1C A;  3UEY A;  2ERW A;  2QQ0 A;  1OMT A;  1X74 A;  1Y1B A;  3UGD A;  1UVG A;  3MEK A;  1UUC A;  1HJA I;  3RU0 A;  2NU4 I;  1TUR A;  5FUV A;  4E1R A;  5FUX A;  3KY9 A;  2FNF X;  4UXH A;  5EX0 A;  1KBF A;  1PCE A;  2ELI A;  1OVO A;  3TJQ A;  1R79 A;  2V53 A;  2WCY A;  1U5K A;  1Y8F A;  1CT4 I;  1X4S A;  3CXL A;  3OXF A;  3SGQ I;  4UXI A;  2NU0 I;  1CSO I;  3VDU A;  1LR9 A;  4UXJ A;  1XBT A;  1KMA A;  2GVI A;  2GKT I;  5FUW A;  4L9M A;  2L7X A;  1FAR A;  1LR7 A;  2ORV A;  1RFH A;  2V1C C;  2A20 A;  3OXG A;  2GKR I;  1H0Z A;  4SGB I;  2P6A C;  1Y1C A;  2L8E A;  2J9R A;  5CCL A;  2QQE A;  1SGD I;  2VRW B;  3UFF A;  1TOT A;  3BJI A;  1XX6 A;  2KMR A;  1UVF A;  2ARP F;  1CE3 A;  4HGU A;  2N1A B;  1SGP I;  1N13 A;  1TBQ R;  2KMQ A;  1Z7K B;  3UEJ A;  2OVO A;  1DS2 I;  3VE5 A;  2M5X A;  1M8C A;  1M8B A;  2J87 A;  3QTL D;  1AN1 I;  1TIH A;  5HQ8 A;  1IW4 A;  2KMO A;  4JCV E;  2ORW A;  2NU2 I;  2BUS A;  2ODD A;  2SGF I;  4GI3 C;  3B4V C;  1TBN A;  1SGN I;  2NU1 I;  3UGI A;  2YQP A;  3SGB I;  1PPF I;  2W0T A;  2OD1 A;  1YU6 C;  2E73 A;  1SGQ I;  1NUB A;  3HH2 C;  1XA6 A;  2JA1 A;  3GOX A;  1IY5 A;  1TUS A;  2JYY A;  1W4R A;  2NU3 I;  1R0R I;  2WVJ A;  1YTP A;  2SGE I;  3OXL A;  5HI7 A;  2SGD I;  3OVO A;  2LEO A;  3E2I A;  2N52 A;  1PTR A;  2XRC A;  2SGP I;  2N71 A;  2KCX A;  2QPO A;  3QWP A;  3FC3 A;  3D00 A;  1BUS A;  1IY6 A;  3OL0 A;  1W3S A;  5FUY A;  4B6D A;  4OVO A;  1CHO I;  5JHW C;  2GKV A;  1FYB A;  5CCM A;  1V1H A;  1OMU A;  1HDL A;  1SGE I;  2ENZ A;  1CGJ I;  1DS3 I;  2QQC A;  2CJS C;  2E5R A;  1FAQ A;  1TBO A;  1SGY I;  2ENN A;  1VDD A;  3SEK C;  1MT1 A;  1HPT A;  4E1P A;  1PTQ A;  1CT0 I;  2DIP A;  3E59 A;  1KBE A;  1TGS I;  4A24 A;  5DAE A;  2YUU A;  2KMP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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