3UGLA

Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase c delta
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
65
structure length
65
Chain Sequence
GSRRASVGSHRFKVYNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCEFIVTD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta
pubmed doi rcsb
molecule tags Metal binding protein
source organism Mus musculus
molecule keywords Proteine kinase C delta type
total genus 11
structure length 65
sequence length 65
chains with identical sequence B
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2011-11-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.20 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 3uglA01
1KBFA 2JA1A 2QPOA 3CXLA 3UGIA 3KY9A 1XA6A 1R79A 2J87A 1XBTA 1FARA 2B8TA 2QQEA 5FUVA 2GVIA 1RFHA 2ORWA 2ENZA 2UZ3A 3UEJA 1XX6A 3UGLA 4UXHA 1W4RA 2ORVA 3BJIA 2ROWA 4UXIA 2ELIA 1PTRA 5FUXA 4FKDA 1KBEA 1TBNA 2QQ0A 4UXJA 2YUUA 5FUYA 2E73A 1FAQA 1Y8FA 2J9RA 2WVJA 4B6DA 3UEYA 3E2IA 5FUWA 3UFFA 3UGDA 1TBOA 2DB6A 2ENNA 4L9MA 2VRWB 2FNFX 1PTQA
chains in the Genus database with same CATH superfamily
2A20A 2N1AB 4WP4A 2LB7A 5J8FA 3GOXA 1FYBA 1X4SA 2W0TA 1TGSI 2KMRA 3TO7A 1U5KA 1H0ZA 1KMAA 2V1CA 2GVIA 3PDNA 1R0RI 2GKRI 4UXHA 2SGPI 3R5BA 5EX0A 5CCLA 1TURA 2N52A 2ROWA 5CCMA 2CJSC 3RU0A 3SGQI 3TOAA 2X3TA 3TOBA 2KMQA 2CWFA 2NU1I 1UVFA 2L8EA 5EX3A 2J9RA 1BMOA 2JW6A 2M5XA 3UEYA 2KCXA 3R5CA 1S20A 2QQCA 5E3RA 2DB6A 2KMPA 1SGPI 1W3SA 2ENNA 2ERWA 1Q9BA 2V53A 3HH2C 2FNFX 4SGBI 1YU6C 1KBFA 1TBRR 2QPOA 1YTPA 3QAHA 3KY9A 1V1IA 1XA6A 2L7XA 4MPIA 2RIJA 2B8TA 2NU4I 2PQ8A 3OXFA 2QQEA 1OMTA 2LUYA 1CSOI 3TO6A 2GKVA 1M8BA 4DNCA 1K7TA 1RFHA 1HJAI 2ENZA 2E5RA 1XX6A 1CE3A 1W4RA 2BUSA 3OXLA 1OVOA 2WGCA 2WCYA 1PTRA 4E1PA 4FKDA 2B0UC 4AMLA 1SGDI 3MEKA 1P9GA 1TIHA 2X52A 1CGII 1K7UA 1LR8A 2E73A 9WGAA 1FAQA 1NXUA 1PJUA 1Y8FA 3SEKC 3VDUA 1PPFI 1LR7A 1Z7KB 1P9ZA 2CWHA 2UVOA 3FSXA 4L9MA 3R5DA 2CWGA 2NU3I 3OXGA 3UEJA 1CT4I 1PCEA 1IY6A 1SGQI 2SGDI 2OD1A 5DAEA 1WKXA 3FSYA 2QQDA 2SGEI 2NU0I 2OU2A 2J87A 4OVOA 2YQPA 1WGTA 1FARA 2F3CI 4E1RA 3D00A 5FUVA 2UZ3A 3E59A 5J8CA 1CGJI 3UGLA 1N13A 1FY7A 2ARPF 1CT2I 1IY5A 1UUCA 2Y0MA 1TUSA 3VDPA 4UXIA 3UGDA 2OVOA 2P6AC 1KBEA 1ULKA 1DS2I 2YUUA 1OMUA 1MJBA 5FUYA 1LR9A 4JCVE 1SGEI 2K9HA 1OYVI 1HEVA 2DKVA 1ULMA 2JYYA 3VE5A 2WVJA 5FUWA 1SGYI 3SGBI 5E3PA 1M8CA 1AN1I 1Y1CA 2VRWB 4HGUA 2XRCA 2JA1A 7WGAA 3OVOA 1MT1A 3CXLA 3QWPA 3UGIA 4A24A 3FC3A 1R79A 2OZUA 1XBTA 1MJ9A 2GIVA 1NUBA 3TJQA 1Y1BA 1WTJA 5HI7A 2JXDA 1UHAA 1UVGA 1WGCA 2N17A 3UOEA 5HQ8A 5JHWC 1Z2IA 2ORWA 1HPTA 1IW4A 1X74A 3OL0A 1TBQR 2SGQI 1DS3I 2ORVA 3BJIA 1VDDA 2SGFI 1HDLA 1MJAA 2ELIA 3B4VC 5FUXA 3TO9A 1BUSA 1TOTA 1V1HA 2KMOA 1TBNA 2QQ0A 4UXJA 3R5AA 1SGNI 2ODDA 5E3QA 2NU2I 3QTLD 2DIPA 1CHOI 4B6DA 4GI3C 3E2IA 1K7VA 1SGRI 2RC4A 2GKTI 2LEOA 1TBOA 2N71A 2V1CC 3UFFA 1CT0I 1ULNA 1PTQA 2JZMA
chains in the Genus database with same CATH topology
2A20A 2N1AB 3GOXA 1FYBA 1X4SA 2W0TA 1TGSI 2KMRA 1KMAA 1U5KA 1H0ZA 2V1CA 2GVIA 3PDNA 1R0RI 2GKRI 4UXHA 2SGPI 5EX0A 5CCLA 1TURA 2N52A 2ROWA 5CCMA 2CJSC 3RU0A 3SGQI 2KMQA 2NU1I 1UVFA 2L8EA 5EX3A 2J9RA 1BMOA 2JW6A 2M5XA 3UEYA 2KCXA 2QQCA 3UGDA 2DB6A 2KMPA 1SGPI 1W3SA 2ENNA 2ERWA 2V53A 3HH2C 4SGBI 2FNFX 1YU6C 1KBFA 1TBRR 2QPOA 1YTPA 3KY9A 1V1IA 1XA6A 2L7XA 2B8TA 2NU4I 3OXFA 2QQEA 1OMTA 2LUYA 1CSOI 2GKVA 1M8BA 1RFHA 1HJAI 2ENZA 2E5RA 1XX6A 1CE3A 1W4RA 2BUSA 3OXLA 1OVOA 2WCYA 1PTRA 4E1PA 4FKDA 2B0UC 1SGDI 3MEKA 1TIHA 1CGII 1LR8A 2E73A 1FAQA 1PJUA 1Y8FA 3SEKC 3VDUA 1PPFI 1LR7A 1Z7KB 4L9MA 1IY6A 2NU3I 3OXGA 3UEJA 1CT4I 1PCEA 1SGQI 2SGDI 2OD1A 5DAEA 2QQDA 2SGEI 2NU0I 4OVOA 2J87A 2YQPA 1FARA 2F3CI 4E1RA 3D00A 5FUVA 2UZ3A 3E59A 1CGJI 3UGLA 1N13A 2ARPF 1CT2I 1IY5A 1UUCA 1TUSA 3VDPA 4UXIA 2OVOA 2P6AC 1KBEA 1DS2I 2YUUA 1OMUA 5FUYA 1LR9A 4JCVE 1SGEI 2K9HA 1OYVI 2JYYA 3VE5A 2WVJA 5FUWA 1SGYI 3SGBI 1Y1CA 1M8CA 1AN1I 2VRWB 4HGUA 2XRCA 2JA1A 3OVOA 1MT1A 3CXLA 3QWPA 3UGIA 4A24A 3FC3A 1R79A 1XBTA 1NUBA 3TJQA 1Y1BA 5HI7A 2JXDA 1UVGA 2N17A 5HQ8A 5JHWC 1IW4A 2ORWA 1HPTA 1X74A 3OL0A 1TBQR 2SGQI 1DS3I 2ORVA 3BJIA 1VDDA 2SGFI 1HDLA 2ELIA 3B4VC 5FUXA 1BUSA 1TOTA 1V1HA 2KMOA 1TBNA 2QQ0A 4UXJA 1SGNI 2ODDA 2NU2I 3QTLD 2DIPA 1CHOI 4B6DA 4GI3C 3E2IA 1SGRI 2GKTI 2LEOA 1TBOA 2N71A 2V1CC 3UFFA 1CT0I 1PTQA 2JZMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KBF A;  2JA1 A;  2QPO A;  3CXL A;  3UGI A;  3KY9 A;  1XA6 A;  1R79 A;  2J87 A;  1XBT A;  1FAR A;  2B8T A;  2QQE A;  5FUV A;  2GVI A;  1RFH A;  2ORW A;  2ENZ A;  2UZ3 A;  3UEJ A;  1XX6 A;  3UGL A;  4UXH A;  1W4R A;  2ORV A;  3BJI A;  2ROW A;  4UXI A;  2ELI A;  1PTR A;  5FUX A;  4FKD A;  1KBE A;  1TBN A;  2QQ0 A;  4UXJ A;  2YUU A;  5FUY A;  2E73 A;  1FAQ A;  1Y8F A;  2J9R A;  2WVJ A;  4B6D A;  3UEY A;  3E2I A;  5FUW A;  3UFF A;  3UGD A;  1TBO A;  2DB6 A;  2ENN A;  4L9M A;  2VRW B;  2FNF X;  1PTQ A; 
#chains in the Genus database with same CATH topology
 2A20 A;  2N1A B;  4WP4 A;  2LB7 A;  5J8F A;  3GOX A;  1FYB A;  1X4S A;  2W0T A;  1TGS I;  2KMR A;  3TO7 A;  1U5K A;  1H0Z A;  1KMA A;  2V1C A;  2GVI A;  3PDN A;  1R0R I;  2GKR I;  4UXH A;  2SGP I;  3R5B A;  5EX0 A;  5CCL A;  1TUR A;  2N52 A;  2ROW A;  5CCM A;  2CJS C;  3RU0 A;  3SGQ I;  3TOA A;  2X3T A;  3TOB A;  2KMQ A;  2CWF A;  2NU1 I;  1UVF A;  2L8E A;  5EX3 A;  2J9R A;  1BMO A;  2JW6 A;  2M5X A;  3UEY A;  2KCX A;  3R5C A;  1S20 A;  2QQC A;  5E3R A;  2DB6 A;  2KMP A;  1SGP I;  1W3S A;  2ENN A;  2ERW A;  1Q9B A;  2V53 A;  3HH2 C;  2FNF X;  4SGB I;  1YU6 C;  1KBF A;  1TBR R;  2QPO A;  1YTP A;  3QAH A;  3KY9 A;  1V1I A;  1XA6 A;  2L7X A;  4MPI A;  2RIJ A;  2B8T A;  2NU4 I;  2PQ8 A;  3OXF A;  2QQE A;  1OMT A;  2LUY A;  1CSO I;  3TO6 A;  2GKV A;  1M8B A;  4DNC A;  1K7T A;  1RFH A;  1HJA I;  2ENZ A;  2E5R A;  1XX6 A;  1CE3 A;  1W4R A;  2BUS A;  3OXL A;  1OVO A;  2WGC A;  2WCY A;  1PTR A;  4E1P A;  4FKD A;  2B0U C;  4AML A;  1SGD I;  3MEK A;  1P9G A;  1TIH A;  2X52 A;  1CGI I;  1K7U A;  1LR8 A;  2E73 A;  9WGA A;  1FAQ A;  1NXU A;  1PJU A;  1Y8F A;  3SEK C;  3VDU A;  1PPF I;  1LR7 A;  1Z7K B;  1P9Z A;  2CWH A;  2UVO A;  3FSX A;  4L9M A;  3R5D A;  2CWG A;  2NU3 I;  3OXG A;  3UEJ A;  1CT4 I;  1PCE A;  1IY6 A;  1SGQ I;  2SGD I;  2OD1 A;  5DAE A;  1WKX A;  3FSY A;  2QQD A;  2SGE I;  2NU0 I;  2OU2 A;  2J87 A;  4OVO A;  2YQP A;  1WGT A;  1FAR A;  2F3C I;  4E1R A;  3D00 A;  5FUV A;  2UZ3 A;  3E59 A;  5J8C A;  1CGJ I;  3UGL A;  1N13 A;  1FY7 A;  2ARP F;  1CT2 I;  1IY5 A;  1UUC A;  2Y0M A;  1TUS A;  3VDP A;  4UXI A;  3UGD A;  2OVO A;  2P6A C;  1KBE A;  1ULK A;  1DS2 I;  2YUU A;  1OMU A;  1MJB A;  5FUY A;  1LR9 A;  4JCV E;  1SGE I;  2K9H A;  1OYV I;  1HEV A;  2DKV A;  1ULM A;  2JYY A;  3VE5 A;  2WVJ A;  5FUW A;  1SGY I;  3SGB I;  5E3P A;  1M8C A;  1AN1 I;  1Y1C A;  2VRW B;  4HGU A;  2XRC A;  2JA1 A;  7WGA A;  3OVO A;  1MT1 A;  3CXL A;  3QWP A;  3UGI A;  4A24 A;  3FC3 A;  1R79 A;  2OZU A;  1XBT A;  1MJ9 A;  2GIV A;  1NUB A;  3TJQ A;  1Y1B A;  1WTJ A;  5HI7 A;  2JXD A;  1UHA A;  1UVG A;  1WGC A;  2N17 A;  3UOE A;  5HQ8 A;  5JHW C;  1Z2I A;  2ORW A;  1HPT A;  1IW4 A;  1X74 A;  3OL0 A;  1TBQ R;  2SGQ I;  1DS3 I;  2ORV A;  3BJI A;  1VDD A;  2SGF I;  1HDL A;  1MJA A;  2ELI A;  3B4V C;  5FUX A;  3TO9 A;  1BUS A;  1TOT A;  1V1H A;  2KMO A;  1TBN A;  2QQ0 A;  4UXJ A;  3R5A A;  1SGN I;  2ODD A;  5E3Q A;  2NU2 I;  3QTL D;  2DIP A;  1CHO I;  4B6D A;  4GI3 C;  3E2I A;  1K7V A;  1SGR I;  2RC4 A;  2GKT I;  2LEO A;  1TBO A;  2N71 A;  2V1C C;  3UFF A;  1CT0 I;  1ULN A;  1PTQ A;  2JZM A; 
#chains in the Genus database with same CATH homology
 2A20 A;  2N1A B;  3GOX A;  1FYB A;  1X4S A;  2W0T A;  1TGS I;  2KMR A;  1KMA A;  1U5K A;  1H0Z A;  2V1C A;  2GVI A;  3PDN A;  1R0R I;  2GKR I;  4UXH A;  2SGP I;  5EX0 A;  5CCL A;  1TUR A;  2N52 A;  2ROW A;  5CCM A;  2CJS C;  3RU0 A;  3SGQ I;  2KMQ A;  2NU1 I;  1UVF A;  2L8E A;  5EX3 A;  2J9R A;  1BMO A;  2JW6 A;  2M5X A;  3UEY A;  2KCX A;  2QQC A;  3UGD A;  2DB6 A;  2KMP A;  1SGP I;  1W3S A;  2ENN A;  2ERW A;  2V53 A;  3HH2 C;  4SGB I;  2FNF X;  1YU6 C;  1KBF A;  1TBR R;  2QPO A;  1YTP A;  3KY9 A;  1V1I A;  1XA6 A;  2L7X A;  2B8T A;  2NU4 I;  3OXF A;  2QQE A;  1OMT A;  2LUY A;  1CSO I;  2GKV A;  1M8B A;  1RFH A;  1HJA I;  2ENZ A;  2E5R A;  1XX6 A;  1CE3 A;  1W4R A;  2BUS A;  3OXL A;  1OVO A;  2WCY A;  1PTR A;  4E1P A;  4FKD A;  2B0U C;  1SGD I;  3MEK A;  1TIH A;  1CGI I;  1LR8 A;  2E73 A;  1FAQ A;  1PJU A;  1Y8F A;  3SEK C;  3VDU A;  1PPF I;  1LR7 A;  1Z7K B;  4L9M A;  1IY6 A;  2NU3 I;  3OXG A;  3UEJ A;  1CT4 I;  1PCE A;  1SGQ I;  2SGD I;  2OD1 A;  5DAE A;  2QQD A;  2SGE I;  2NU0 I;  4OVO A;  2J87 A;  2YQP A;  1FAR A;  2F3C I;  4E1R A;  3D00 A;  5FUV A;  2UZ3 A;  3E59 A;  1CGJ I;  3UGL A;  1N13 A;  2ARP F;  1CT2 I;  1IY5 A;  1UUC A;  1TUS A;  3VDP A;  4UXI A;  2OVO A;  2P6A C;  1KBE A;  1DS2 I;  2YUU A;  1OMU A;  5FUY A;  1LR9 A;  4JCV E;  1SGE I;  2K9H A;  1OYV I;  2JYY A;  3VE5 A;  2WVJ A;  5FUW A;  1SGY I;  3SGB I;  1Y1C A;  1M8C A;  1AN1 I;  2VRW B;  4HGU A;  2XRC A;  2JA1 A;  3OVO A;  1MT1 A;  3CXL A;  3QWP A;  3UGI A;  4A24 A;  3FC3 A;  1R79 A;  1XBT A;  1NUB A;  3TJQ A;  1Y1B A;  5HI7 A;  2JXD A;  1UVG A;  2N17 A;  5HQ8 A;  5JHW C;  1IW4 A;  2ORW A;  1HPT A;  1X74 A;  3OL0 A;  1TBQ R;  2SGQ I;  1DS3 I;  2ORV A;  3BJI A;  1VDD A;  2SGF I;  1HDL A;  2ELI A;  3B4V C;  5FUX A;  1BUS A;  1TOT A;  1V1H A;  2KMO A;  1TBN A;  2QQ0 A;  4UXJ A;  1SGN I;  2ODD A;  2NU2 I;  3QTL D;  2DIP A;  1CHO I;  4B6D A;  4GI3 C;  3E2I A;  1SGR I;  2GKT I;  2LEO A;  1TBO A;  2N71 A;  2V1C C;  3UFF A;  1CT0 I;  1PTQ A;  2JZM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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