3UGLA

Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase c delta
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
65
structure length
65
Chain Sequence
GSRRASVGSHRFKVYNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCEFIVTD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta
pubmed doi rcsb
molecule tags Metal binding protein
source organism Mus musculus
molecule keywords Proteine kinase C delta type
total genus 11
structure length 65
sequence length 65
chains with identical sequence B
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2011-11-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.20 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 3uglA01
2ENNA 2WVJA 1XA6A 1FARA 3CXLA 4B6DA 2UZ3A 3KY9A 4UXJA 1W4RA 1FAQA 2ENZA 1Y8FA 2ROWA 4UXIA 3UGLA 3UEJA 1XBTA 1XX6A 2ELIA 2VRWB 5FUVA 2J87A 4UXHA 5FUYA 4L9MA 3UEYA 3UGDA 2YUUA 5FUXA 1TBOA 1TBNA 3UFFA 1PTRA 3UGIA 1KBEA 2ORWA 1KBFA 2FNFX 4FKDA 2E73A 2QQ0A 3E2IA 2QPOA 2ORVA 2GVIA 1R79A 2QQEA 2B8TA 3BJIA 2J9RA 1PTQA 2DB6A 2JA1A 1RFHA 5FUWA
chains in the Genus database with same CATH superfamily
1HPTA 5DAEA 2LB7A 2Y0MA 1IY5A 2K9HA 1FARA 1CSOI 1NUBA 3RU0A 2KMRA 4OVOA 1PCEA 1OYVI 3R5AA 2WGCA 2GKTI 2ODDA 2ROWA 5E3RA 3SGBI 3UGLA 1CE3A 2LUYA 1XX6A 2V1CC 1DS2I 1DS3I 1FY7A 1BMOA 2VRWB 1PPFI 1H0ZA 4UXHA 3TOAA 2V53A 2CJSC 5CCLA 1U5KA 1SGDI 3QWPA 3SGQI 2E5RA 3TO6A 2KMQA 2ORWA 1TOTA 3E2IA 1LR8A 2NU3I 1WGTA 2QQDA 2QQEA 3VE5A 5J8FA 1PJUA 2SGDI 4DNCA 2DKVA 4AMLA 1K7UA 2DIPA 1CT2I 2RC4A 2KCXA 3MEKA 1BUSA 1RFHA 2JXDA 1K7TA 3OXGA 2WVJA 1XA6A 1NXUA 2NU2I 2L8EA 1SGEI 4UXJA 1M8BA 1WKXA 1W4RA 2JZMA 1K7VA 1UVGA 2GKRI 2LEOA 2OVOA 2ENZA 4E1RA 1X4SA 1UUCA 2QQCA 5HQ8A 1TUSA 2M5XA 1SGPI 4UXIA 4A24A 3UEJA 2ERWA 3QTLD 4GI3C 1TURA 1Q9BA 1OMUA 1TGSI 1UHAA 1UVFA 2WCYA 3TO7A 1CHOI 2YUUA 5FUXA 1V1HA 1R0RI 4SGBI 1YTPA 2P6AC 3B4VC 3FSXA 1WGCA 2F3CI 3QAHA 3UFFA 1CT4I 1KBEA 1P9GA 3HH2C 1KBFA 1M8CA 1N13A 2GVIA 1R79A 2CWHA 3UOEA 1Y1BA 1CGJI 3GOXA 1KMAA 1YU6C 2J9RA 1Z2IA 2NU4I 1HJAI 3R5BA 2N1AB 3OL0A 1MJAA 2SGFI 2SGPI 3OVOA 4MPIA 1AN1I 1SGYI 3R5CA 3PDNA 1S20A 1P9ZA 1HEVA 4B6DA 1Y8FA 3TO9A 2X52A 2PQ8A 3FC3A 1OMTA 2CWGA 1MJ9A 3FSYA 2N52A 2OZUA 1TIHA 5FUVA 4JCVE 1FYBA 1ULKA 1HDLA 2BUSA 3OXLA 2A20A 4L9MA 4WP4A 3UGDA 9WGAA 1TBOA 1CT0I 1LR9A 5E3PA 5EX0A 2KMPA 1SGRI 5JHWC 3UGIA 5J8CA 2L7XA 2OU2A 4FKDA 1TBRR 2JW6A 2QPOA 2V1CA 5HI7A 2KMOA 1LR7A 1SGNI 3E59A 2SGQI 1IW4A 2SGEI 1PTQA 3VDUA 3TJQA 1Z7KB 2GIVA 1TBQR 3OXFA 5FUWA 3SEKC 2CWFA 2JYYA 2X3TA 2ENNA 2NU1I 4E1PA 1V1IA 2N17A 3CXLA 2UZ3A 3KY9A 1FAQA 1MJBA 4HGUA 1Y1CA 2W0TA 1W3SA 1WTJA 2GKVA 1X74A 3TOBA 2YQPA 1XBTA 1ULMA 2ELIA 5E3QA 5EX3A 3D00A 1OVOA 2J87A 1ULNA 5FUYA 3UEYA 1CGII 1TBNA 7WGAA 2N71A 2RIJA 1PTRA 2NU0I 2XRCA 1SGQI 2FNFX 2E73A 2QQ0A 1IY6A 2ORVA 2B0UC 1VDDA 2OD1A 2B8TA 2UVOA 3BJIA 2ARPF 2DB6A 2JA1A 5CCMA 1MT1A 3R5DA 3VDPA
chains in the Genus database with same CATH topology
1HPTA 5DAEA 1IY5A 2K9HA 1FARA 1CSOI 1NUBA 3RU0A 2KMRA 4OVOA 1PCEA 1OYVI 2GKTI 2ODDA 2ROWA 3SGBI 1CE3A 3UGLA 2LUYA 1XX6A 2V1CC 1DS2I 1DS3I 1BMOA 2VRWB 1H0ZA 1PPFI 4UXHA 2V53A 2CJSC 5CCLA 1U5KA 1SGDI 3QWPA 3SGQI 2E5RA 2KMQA 2ORWA 1TOTA 3E2IA 1LR8A 2NU3I 2QQDA 2QQEA 3VE5A 1PJUA 2SGDI 2DIPA 1BUSA 1CT2I 3MEKA 2KCXA 1RFHA 2JXDA 3OXGA 2WVJA 1XA6A 2NU2I 2L8EA 1SGEI 4UXJA 1M8BA 2JZMA 1W4RA 2LEOA 2OVOA 1UVGA 2GKRI 4E1RA 2ENZA 1X4SA 1UUCA 2QQCA 5HQ8A 1TUSA 2M5XA 1SGPI 4UXIA 4A24A 3UEJA 2ERWA 3QTLD 4GI3C 1TURA 1UVFA 1OMUA 1TGSI 2WCYA 1CHOI 2YUUA 5FUXA 1V1HA 1R0RI 4SGBI 1YTPA 2P6AC 3B4VC 2F3CI 3UFFA 1CT4I 1KBEA 3HH2C 1KBFA 1M8CA 1N13A 2GVIA 1R79A 3GOXA 1KMAA 1Y1BA 1CGJI 1YU6C 2J9RA 2NU4I 1HJAI 2N1AB 3OL0A 2SGFI 2SGPI 3OVOA 1AN1I 1SGYI 3PDNA 4B6DA 1Y8FA 3FC3A 1OMTA 2N52A 1TIHA 5FUVA 4JCVE 1FYBA 1HDLA 2BUSA 3OXLA 2A20A 4L9MA 3UGDA 1TBOA 1CT0I 1LR9A 5EX0A 2KMPA 1SGRI 5JHWC 3UGIA 2L7XA 4FKDA 1TBRR 2JW6A 2QPOA 2V1CA 5HI7A 2KMOA 1LR7A 1SGNI 3E59A 2SGQI 1IW4A 2SGEI 1PTQA 3VDUA 3TJQA 1Z7KB 3OXFA 1TBQR 5FUWA 3SEKC 2JYYA 2ENNA 2NU1I 4E1PA 1V1IA 2N17A 3CXLA 2UZ3A 3KY9A 1FAQA 4HGUA 1Y1CA 2W0TA 1W3SA 2GKVA 1X74A 2YQPA 1XBTA 2ELIA 5EX3A 3D00A 1OVOA 2J87A 5FUYA 3UEYA 1CGII 1TBNA 2N71A 1PTRA 2NU0I 2XRCA 1SGQI 2FNFX 2E73A 2QQ0A 1IY6A 2ORVA 2B0UC 1VDDA 2OD1A 2B8TA 3BJIA 2ARPF 2DB6A 2JA1A 5CCMA 1MT1A 3VDPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ENN A;  2WVJ A;  1XA6 A;  1FAR A;  3CXL A;  4B6D A;  2UZ3 A;  3KY9 A;  4UXJ A;  1W4R A;  1FAQ A;  2ENZ A;  1Y8F A;  2ROW A;  4UXI A;  3UGL A;  3UEJ A;  1XBT A;  1XX6 A;  2ELI A;  2VRW B;  5FUV A;  2J87 A;  4UXH A;  5FUY A;  4L9M A;  3UEY A;  3UGD A;  2YUU A;  5FUX A;  1TBO A;  1TBN A;  3UFF A;  1PTR A;  3UGI A;  1KBE A;  2ORW A;  1KBF A;  2FNF X;  4FKD A;  2E73 A;  2QQ0 A;  3E2I A;  2QPO A;  2ORV A;  2GVI A;  1R79 A;  2QQE A;  2B8T A;  3BJI A;  2J9R A;  1PTQ A;  2DB6 A;  2JA1 A;  1RFH A;  5FUW A; 
#chains in the Genus database with same CATH topology
 1HPT A;  5DAE A;  2LB7 A;  2Y0M A;  1IY5 A;  2K9H A;  1FAR A;  1CSO I;  1NUB A;  3RU0 A;  2KMR A;  4OVO A;  1PCE A;  1OYV I;  3R5A A;  2WGC A;  2GKT I;  2ODD A;  2ROW A;  5E3R A;  3SGB I;  3UGL A;  1CE3 A;  2LUY A;  1XX6 A;  2V1C C;  1DS2 I;  1DS3 I;  1FY7 A;  1BMO A;  2VRW B;  1PPF I;  1H0Z A;  4UXH A;  3TOA A;  2V53 A;  2CJS C;  5CCL A;  1U5K A;  1SGD I;  3QWP A;  3SGQ I;  2E5R A;  3TO6 A;  2KMQ A;  2ORW A;  1TOT A;  3E2I A;  1LR8 A;  2NU3 I;  1WGT A;  2QQD A;  2QQE A;  3VE5 A;  5J8F A;  1PJU A;  2SGD I;  4DNC A;  2DKV A;  4AML A;  1K7U A;  2DIP A;  1CT2 I;  2RC4 A;  2KCX A;  3MEK A;  1BUS A;  1RFH A;  2JXD A;  1K7T A;  3OXG A;  2WVJ A;  1XA6 A;  1NXU A;  2NU2 I;  2L8E A;  1SGE I;  4UXJ A;  1M8B A;  1WKX A;  1W4R A;  2JZM A;  1K7V A;  1UVG A;  2GKR I;  2LEO A;  2OVO A;  2ENZ A;  4E1R A;  1X4S A;  1UUC A;  2QQC A;  5HQ8 A;  1TUS A;  2M5X A;  1SGP I;  4UXI A;  4A24 A;  3UEJ A;  2ERW A;  3QTL D;  4GI3 C;  1TUR A;  1Q9B A;  1OMU A;  1TGS I;  1UHA A;  1UVF A;  2WCY A;  3TO7 A;  1CHO I;  2YUU A;  5FUX A;  1V1H A;  1R0R I;  4SGB I;  1YTP A;  2P6A C;  3B4V C;  3FSX A;  1WGC A;  2F3C I;  3QAH A;  3UFF A;  1CT4 I;  1KBE A;  1P9G A;  3HH2 C;  1KBF A;  1M8C A;  1N13 A;  2GVI A;  1R79 A;  2CWH A;  3UOE A;  1Y1B A;  1CGJ I;  3GOX A;  1KMA A;  1YU6 C;  2J9R A;  1Z2I A;  2NU4 I;  1HJA I;  3R5B A;  2N1A B;  3OL0 A;  1MJA A;  2SGF I;  2SGP I;  3OVO A;  4MPI A;  1AN1 I;  1SGY I;  3R5C A;  3PDN A;  1S20 A;  1P9Z A;  1HEV A;  4B6D A;  1Y8F A;  3TO9 A;  2X52 A;  2PQ8 A;  3FC3 A;  1OMT A;  2CWG A;  1MJ9 A;  3FSY A;  2N52 A;  2OZU A;  1TIH A;  5FUV A;  4JCV E;  1FYB A;  1ULK A;  1HDL A;  2BUS A;  3OXL A;  2A20 A;  4L9M A;  4WP4 A;  3UGD A;  9WGA A;  1TBO A;  1CT0 I;  1LR9 A;  5E3P A;  5EX0 A;  2KMP A;  1SGR I;  5JHW C;  3UGI A;  5J8C A;  2L7X A;  2OU2 A;  4FKD A;  1TBR R;  2JW6 A;  2QPO A;  2V1C A;  5HI7 A;  2KMO A;  1LR7 A;  1SGN I;  3E59 A;  2SGQ I;  1IW4 A;  2SGE I;  1PTQ A;  3VDU A;  3TJQ A;  1Z7K B;  2GIV A;  1TBQ R;  3OXF A;  5FUW A;  3SEK C;  2CWF A;  2JYY A;  2X3T A;  2ENN A;  2NU1 I;  4E1P A;  1V1I A;  2N17 A;  3CXL A;  2UZ3 A;  3KY9 A;  1FAQ A;  1MJB A;  4HGU A;  1Y1C A;  2W0T A;  1W3S A;  1WTJ A;  2GKV A;  1X74 A;  3TOB A;  2YQP A;  1XBT A;  1ULM A;  2ELI A;  5E3Q A;  5EX3 A;  3D00 A;  1OVO A;  2J87 A;  1ULN A;  5FUY A;  3UEY A;  1CGI I;  1TBN A;  7WGA A;  2N71 A;  2RIJ A;  1PTR A;  2NU0 I;  2XRC A;  1SGQ I;  2FNF X;  2E73 A;  2QQ0 A;  1IY6 A;  2ORV A;  2B0U C;  1VDD A;  2OD1 A;  2B8T A;  2UVO A;  3BJI A;  2ARP F;  2DB6 A;  2JA1 A;  5CCM A;  1MT1 A;  3R5D A;  3VDP A; 
#chains in the Genus database with same CATH homology
 1HPT A;  5DAE A;  1IY5 A;  2K9H A;  1FAR A;  1CSO I;  1NUB A;  3RU0 A;  2KMR A;  4OVO A;  1PCE A;  1OYV I;  2GKT I;  2ODD A;  2ROW A;  3SGB I;  1CE3 A;  3UGL A;  2LUY A;  1XX6 A;  2V1C C;  1DS2 I;  1DS3 I;  1BMO A;  2VRW B;  1H0Z A;  1PPF I;  4UXH A;  2V53 A;  2CJS C;  5CCL A;  1U5K A;  1SGD I;  3QWP A;  3SGQ I;  2E5R A;  2KMQ A;  2ORW A;  1TOT A;  3E2I A;  1LR8 A;  2NU3 I;  2QQD A;  2QQE A;  3VE5 A;  1PJU A;  2SGD I;  2DIP A;  1BUS A;  1CT2 I;  3MEK A;  2KCX A;  1RFH A;  2JXD A;  3OXG A;  2WVJ A;  1XA6 A;  2NU2 I;  2L8E A;  1SGE I;  4UXJ A;  1M8B A;  2JZM A;  1W4R A;  2LEO A;  2OVO A;  1UVG A;  2GKR I;  4E1R A;  2ENZ A;  1X4S A;  1UUC A;  2QQC A;  5HQ8 A;  1TUS A;  2M5X A;  1SGP I;  4UXI A;  4A24 A;  3UEJ A;  2ERW A;  3QTL D;  4GI3 C;  1TUR A;  1UVF A;  1OMU A;  1TGS I;  2WCY A;  1CHO I;  2YUU A;  5FUX A;  1V1H A;  1R0R I;  4SGB I;  1YTP A;  2P6A C;  3B4V C;  2F3C I;  3UFF A;  1CT4 I;  1KBE A;  3HH2 C;  1KBF A;  1M8C A;  1N13 A;  2GVI A;  1R79 A;  3GOX A;  1KMA A;  1Y1B A;  1CGJ I;  1YU6 C;  2J9R A;  2NU4 I;  1HJA I;  2N1A B;  3OL0 A;  2SGF I;  2SGP I;  3OVO A;  1AN1 I;  1SGY I;  3PDN A;  4B6D A;  1Y8F A;  3FC3 A;  1OMT A;  2N52 A;  1TIH A;  5FUV A;  4JCV E;  1FYB A;  1HDL A;  2BUS A;  3OXL A;  2A20 A;  4L9M A;  3UGD A;  1TBO A;  1CT0 I;  1LR9 A;  5EX0 A;  2KMP A;  1SGR I;  5JHW C;  3UGI A;  2L7X A;  4FKD A;  1TBR R;  2JW6 A;  2QPO A;  2V1C A;  5HI7 A;  2KMO A;  1LR7 A;  1SGN I;  3E59 A;  2SGQ I;  1IW4 A;  2SGE I;  1PTQ A;  3VDU A;  3TJQ A;  1Z7K B;  3OXF A;  1TBQ R;  5FUW A;  3SEK C;  2JYY A;  2ENN A;  2NU1 I;  4E1P A;  1V1I A;  2N17 A;  3CXL A;  2UZ3 A;  3KY9 A;  1FAQ A;  4HGU A;  1Y1C A;  2W0T A;  1W3S A;  2GKV A;  1X74 A;  2YQP A;  1XBT A;  2ELI A;  5EX3 A;  3D00 A;  1OVO A;  2J87 A;  5FUY A;  3UEY A;  1CGI I;  1TBN A;  2N71 A;  1PTR A;  2NU0 I;  2XRC A;  1SGQ I;  2FNF X;  2E73 A;  2QQ0 A;  1IY6 A;  2ORV A;  2B0U C;  1VDD A;  2OD1 A;  2B8T A;  3BJI A;  2ARP F;  2DB6 A;  2JA1 A;  5CCM A;  1MT1 A;  3VDP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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