3OL0A

Crystal structure of monofoil-4p homo-trimer: de novo designed monomer trefoil-fold sub-domain which forms homo-trimer assembly
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
43
structure length
43
Chain Sequence
HHHPVLLKSTETGQYLRINPDGTVDGTRDRSDPHIQFQISPEG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Experimental support for the evolution of symmetric protein architecture from a simple peptide motif.
pubmed doi rcsb
molecule tags De novo protein
source organism Synthetic construct
molecule keywords de novo designed monomer trefoil-fold sub-domain which forms
total genus 5
structure length 43
sequence length 43
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2010-08-25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.260 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 3ol0A00
3OL0A
chains in the Genus database with same CATH superfamily
2LUYA 5EX0A 5DAEA 2CWHA 3TJQA 2W0TA 1MJ9A 1PTRA 4HGUA 1SGEI 5FUWA 1FAQA 1SGQI 2BUSA 3R5CA 2V53A 1N13A 2DIPA 3D00A 2M5XA 1TURA 1PCEA 4WP4A 3UEJA 5CCMA 1DS2I 2NU3I 2V1CA 3TO6A 2ARPF 2KMQA 2WCYA 1CT0I 1LR9A 2A20A 2ELIA 1TBRR 2CJSC 1NXUA 2N1AB 2UVOA 1PJUA 5E3QA 2DB6A 2SGQI 2J87A 2GIVA 3FSXA 2SGEI 1TBNA 3UGLA 1PPFI 2KMOA 2E73A 1MJAA 1PTQA 2KMPA 2ORWA 4FKDA 4UXIA 3SEKC 3RU0A 5HI7A 2ENNA 1TUSA 5J8FA 3KY9A 3VDUA 5CCLA 2RIJA 4SGBI 3OXLA 2OVOA 1XBTA 3OXFA 3QWPA 1M8CA 1LR8A 2JXDA 4UXJA 5JHWC 1VDDA 2P6AC 1X4SA 1TBOA 2V1CC 1WGTA 1TIHA 1ULMA 2DKVA 4UXHA 1MJBA 1UVGA 5FUYA 3MEKA 1TGSI 2ODDA 1P9GA 1CE3A 1R79A 2GVIA 1YU6C 2ROWA 1V1HA 1OVOA 1CT4I 2QQDA 1U5KA 1S20A 3R5DA 1BMOA 1OMTA 4MPIA 2WVJA 2F3CI 1HPTA 2K9HA 1Y8FA 1P9ZA 2N17A 1FY7A 1LR7A 2N71A 4JCVE 3OL0A 5HQ8A 1Y1BA 2LEOA 1HJAI 2CWGA 1W4RA 1SGRI 3B4VC 3UOEA 3FSYA 2JZMA 1Z2IA 1W3SA 2PQ8A 2VRWB 1UVFA 2OU2A 3OVOA 1CGJI 3UGDA 1TBQR 2SGDI 1NUBA 2ORVA 2ERWA 2Y0MA 3QAHA 3UFFA 1UHAA 1UUCA 1X74A 2OZUA 2JA1A 3OXGA 2X3TA 2JYYA 1Y1CA 2RC4A 3PDNA 4DNCA 7WGAA 1TOTA 3E59A 1V1IA 3QTLD 5E3PA 2NU4I 1XX6A 1OMUA 2LB7A 1SGDI 1H0ZA 2E5RA 4E1RA 2L8EA 2ENZA 2QQ0A 1WTJA 2YUUA 2QPOA 4OVOA 3TOBA 2X52A 3VE5A 3VDPA 3R5BA 2SGPI 1FARA 2WGCA 1IY5A 1DS3I 1SGPI 4A24A 1BUSA 1YTPA 3TO7A 4L9MA 2L7XA 3CXLA 5FUXA 2NU1I 2OD1A 2FNFX 5E3RA 3SGBI 4AMLA 5J8CA 1CHOI 2YQPA 3FC3A 1KBFA 3TO9A 4E1PA 1Z7KB 1AN1I 2KMRA 1OYVI 3SGQI 1R0RI 3UEYA 1ULKA 2N52A 2JW6A 2KCXA 3GOXA 1CGII 4GI3C 1Q9BA 1K7UA 1MT1A 1HEVA 2GKVA 1SGYI 1RFHA 1WGCA 1WKXA 2NU2I 2SGFI 1SGNI 1KBEA 2B0UC 2NU0I 3UGIA 2GKRI 2CWFA 2GKTI 5FUVA 2XRCA 1HDLA 1K7VA 1IY6A 1CT2I 1KMAA 2UZ3A 3TOAA 1IW4A 3BJIA 2J9RA 2QQEA 3E2IA 4B6DA 9WGAA 1K7TA 5EX3A 1ULNA 2B8TA 1CSOI 3HH2C 1M8BA 1XA6A 1FYBA 2QQCA 3R5AA
chains in the Genus database with same CATH topology
2LUYA 5EX0A 5DAEA 3TJQA 2W0TA 1PTRA 4HGUA 1SGEI 5FUWA 1FAQA 1SGQI 2BUSA 2V53A 1N13A 2DIPA 3D00A 2M5XA 1TURA 1PCEA 3UEJA 5CCMA 1DS2I 2NU3I 2V1CA 2ARPF 2KMQA 2WCYA 1CT0I 1LR9A 2A20A 2ELIA 1TBRR 2CJSC 2N1AB 3UFFA 5CCLA 1PJUA 2DB6A 2SGQI 2J87A 2SGEI 1TBNA 3UGLA 1PPFI 2KMOA 2E73A 1PTQA 2KMPA 4FKDA 2ORWA 4UXIA 3SEKC 3RU0A 5HI7A 2ENNA 1TUSA 3KY9A 3VDUA 4SGBI 3OXLA 2OVOA 1XBTA 3OXFA 3QWPA 1M8CA 1LR8A 2JXDA 4UXJA 5JHWC 1VDDA 2P6AC 1X4SA 1TBOA 2V1CC 1TIHA 4UXHA 1UVGA 5FUYA 3MEKA 1TGSI 2ODDA 1CE3A 1R79A 2GVIA 1YU6C 2ROWA 1V1HA 1OVOA 1CT4I 2QQDA 1U5KA 1BMOA 1OMTA 2WVJA 2F3CI 1HPTA 2K9HA 1Y8FA 2N71A 2N17A 4JCVE 1LR7A 3OL0A 5HQ8A 1Y1BA 2LEOA 1HJAI 1W4RA 1SGRI 3B4VC 2JZMA 1W3SA 2VRWB 1UVFA 3OVOA 1CGJI 3UGDA 1TBQR 2SGDI 1NUBA 2ORVA 2ERWA 1UUCA 1X74A 2JA1A 3OXGA 2JYYA 1Y1CA 3PDNA 1TOTA 3E59A 1V1IA 3QTLD 2NU4I 1XX6A 1OMUA 1SGDI 1H0ZA 2E5RA 4E1RA 2L8EA 2ENZA 2QQ0A 2YUUA 2QPOA 4OVOA 3VE5A 3VDPA 2SGPI 1FARA 1IY5A 1DS3I 1SGPI 4A24A 1BUSA 1YTPA 4L9MA 2L7XA 3CXLA 5FUXA 2NU1I 2OD1A 2FNFX 3SGBI 1KBFA 1CHOI 2YQPA 3FC3A 4E1PA 1Z7KB 1AN1I 2KMRA 1OYVI 3SGQI 1R0RI 3UEYA 2N52A 2JW6A 2KCXA 3GOXA 1CGII 4GI3C 1MT1A 2GKVA 1SGYI 1RFHA 3UGIA 2NU2I 2SGFI 1SGNI 1KBEA 2B0UC 2NU0I 2GKRI 2GKTI 5FUVA 2XRCA 1HDLA 1IY6A 1CT2I 1KMAA 2UZ3A 1IW4A 3BJIA 2J9RA 2QQEA 3E2IA 4B6DA 5EX3A 2B8TA 3HH2C 1CSOI 1FYBA 1M8BA 1XA6A 2QQCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OL0 A; 
#chains in the Genus database with same CATH topology
 2LUY A;  5EX0 A;  5DAE A;  2CWH A;  3TJQ A;  2W0T A;  1MJ9 A;  1PTR A;  4HGU A;  1SGE I;  5FUW A;  1FAQ A;  1SGQ I;  2BUS A;  3R5C A;  2V53 A;  1N13 A;  2DIP A;  3D00 A;  2M5X A;  1TUR A;  1PCE A;  4WP4 A;  3UEJ A;  5CCM A;  1DS2 I;  2NU3 I;  2V1C A;  3TO6 A;  2ARP F;  2KMQ A;  2WCY A;  1CT0 I;  1LR9 A;  2A20 A;  2ELI A;  1TBR R;  2CJS C;  1NXU A;  2N1A B;  2UVO A;  1PJU A;  5E3Q A;  2DB6 A;  2SGQ I;  2J87 A;  2GIV A;  3FSX A;  2SGE I;  1TBN A;  3UGL A;  1PPF I;  2KMO A;  2E73 A;  1MJA A;  1PTQ A;  2KMP A;  2ORW A;  4FKD A;  4UXI A;  3SEK C;  3RU0 A;  5HI7 A;  2ENN A;  1TUS A;  5J8F A;  3KY9 A;  3VDU A;  5CCL A;  2RIJ A;  4SGB I;  3OXL A;  2OVO A;  1XBT A;  3OXF A;  3QWP A;  1M8C A;  1LR8 A;  2JXD A;  4UXJ A;  5JHW C;  1VDD A;  2P6A C;  1X4S A;  1TBO A;  2V1C C;  1WGT A;  1TIH A;  1ULM A;  2DKV A;  4UXH A;  1MJB A;  1UVG A;  5FUY A;  3MEK A;  1TGS I;  2ODD A;  1P9G A;  1CE3 A;  1R79 A;  2GVI A;  1YU6 C;  2ROW A;  1V1H A;  1OVO A;  1CT4 I;  2QQD A;  1U5K A;  1S20 A;  3R5D A;  1BMO A;  1OMT A;  4MPI A;  2WVJ A;  2F3C I;  1HPT A;  2K9H A;  1Y8F A;  1P9Z A;  2N17 A;  1FY7 A;  1LR7 A;  2N71 A;  4JCV E;  3OL0 A;  5HQ8 A;  1Y1B A;  2LEO A;  1HJA I;  2CWG A;  1W4R A;  1SGR I;  3B4V C;  3UOE A;  3FSY A;  2JZM A;  1Z2I A;  1W3S A;  2PQ8 A;  2VRW B;  1UVF A;  2OU2 A;  3OVO A;  1CGJ I;  3UGD A;  1TBQ R;  2SGD I;  1NUB A;  2ORV A;  2ERW A;  2Y0M A;  3QAH A;  3UFF A;  1UHA A;  1UUC A;  1X74 A;  2OZU A;  2JA1 A;  3OXG A;  2X3T A;  2JYY A;  1Y1C A;  2RC4 A;  3PDN A;  4DNC A;  7WGA A;  1TOT A;  3E59 A;  1V1I A;  3QTL D;  5E3P A;  2NU4 I;  1XX6 A;  1OMU A;  2LB7 A;  1SGD I;  1H0Z A;  2E5R A;  4E1R A;  2L8E A;  2ENZ A;  2QQ0 A;  1WTJ A;  2YUU A;  2QPO A;  4OVO A;  3TOB A;  2X52 A;  3VE5 A;  3VDP A;  3R5B A;  2SGP I;  1FAR A;  2WGC A;  1IY5 A;  1DS3 I;  1SGP I;  4A24 A;  1BUS A;  1YTP A;  3TO7 A;  4L9M A;  2L7X A;  3CXL A;  5FUX A;  2NU1 I;  2OD1 A;  2FNF X;  5E3R A;  3SGB I;  4AML A;  5J8C A;  1CHO I;  2YQP A;  3FC3 A;  1KBF A;  3TO9 A;  4E1P A;  1Z7K B;  1AN1 I;  2KMR A;  1OYV I;  3SGQ I;  1R0R I;  3UEY A;  1ULK A;  2N52 A;  2JW6 A;  2KCX A;  3GOX A;  1CGI I;  4GI3 C;  1Q9B A;  1K7U A;  1MT1 A;  1HEV A;  2GKV A;  1SGY I;  1RFH A;  1WGC A;  1WKX A;  2NU2 I;  2SGF I;  1SGN I;  1KBE A;  2B0U C;  2NU0 I;  3UGI A;  2GKR I;  2CWF A;  2GKT I;  5FUV A;  2XRC A;  1HDL A;  1K7V A;  1IY6 A;  1CT2 I;  1KMA A;  2UZ3 A;  3TOA A;  1IW4 A;  3BJI A;  2J9R A;  2QQE A;  3E2I A;  4B6D A;  9WGA A;  1K7T A;  5EX3 A;  1ULN A;  2B8T A;  1CSO I;  3HH2 C;  1M8B A;  1XA6 A;  1FYB A;  2QQC A;  3R5A A; 
#chains in the Genus database with same CATH homology
 2LUY A;  5EX0 A;  5DAE A;  3TJQ A;  2W0T A;  1PTR A;  4HGU A;  1SGE I;  5FUW A;  1FAQ A;  1SGQ I;  2BUS A;  2V53 A;  1N13 A;  2DIP A;  3D00 A;  2M5X A;  1TUR A;  1PCE A;  3UEJ A;  5CCM A;  1DS2 I;  2NU3 I;  2V1C A;  2ARP F;  2KMQ A;  2WCY A;  1CT0 I;  1LR9 A;  2A20 A;  2ELI A;  1TBR R;  2CJS C;  2N1A B;  3UFF A;  5CCL A;  1PJU A;  2DB6 A;  2SGQ I;  2J87 A;  2SGE I;  1TBN A;  3UGL A;  1PPF I;  2KMO A;  2E73 A;  1PTQ A;  2KMP A;  4FKD A;  2ORW A;  4UXI A;  3SEK C;  3RU0 A;  5HI7 A;  2ENN A;  1TUS A;  3KY9 A;  3VDU A;  4SGB I;  3OXL A;  2OVO A;  1XBT A;  3OXF A;  3QWP A;  1M8C A;  1LR8 A;  2JXD A;  4UXJ A;  5JHW C;  1VDD A;  2P6A C;  1X4S A;  1TBO A;  2V1C C;  1TIH A;  4UXH A;  1UVG A;  5FUY A;  3MEK A;  1TGS I;  2ODD A;  1CE3 A;  1R79 A;  2GVI A;  1YU6 C;  2ROW A;  1V1H A;  1OVO A;  1CT4 I;  2QQD A;  1U5K A;  1BMO A;  1OMT A;  2WVJ A;  2F3C I;  1HPT A;  2K9H A;  1Y8F A;  2N71 A;  2N17 A;  4JCV E;  1LR7 A;  3OL0 A;  5HQ8 A;  1Y1B A;  2LEO A;  1HJA I;  1W4R A;  1SGR I;  3B4V C;  2JZM A;  1W3S A;  2VRW B;  1UVF A;  3OVO A;  1CGJ I;  3UGD A;  1TBQ R;  2SGD I;  1NUB A;  2ORV A;  2ERW A;  1UUC A;  1X74 A;  2JA1 A;  3OXG A;  2JYY A;  1Y1C A;  3PDN A;  1TOT A;  3E59 A;  1V1I A;  3QTL D;  2NU4 I;  1XX6 A;  1OMU A;  1SGD I;  1H0Z A;  2E5R A;  4E1R A;  2L8E A;  2ENZ A;  2QQ0 A;  2YUU A;  2QPO A;  4OVO A;  3VE5 A;  3VDP A;  2SGP I;  1FAR A;  1IY5 A;  1DS3 I;  1SGP I;  4A24 A;  1BUS A;  1YTP A;  4L9M A;  2L7X A;  3CXL A;  5FUX A;  2NU1 I;  2OD1 A;  2FNF X;  3SGB I;  1KBF A;  1CHO I;  2YQP A;  3FC3 A;  4E1P A;  1Z7K B;  1AN1 I;  2KMR A;  1OYV I;  3SGQ I;  1R0R I;  3UEY A;  2N52 A;  2JW6 A;  2KCX A;  3GOX A;  1CGI I;  4GI3 C;  1MT1 A;  2GKV A;  1SGY I;  1RFH A;  3UGI A;  2NU2 I;  2SGF I;  1SGN I;  1KBE A;  2B0U C;  2NU0 I;  2GKR I;  2GKT I;  5FUV A;  2XRC A;  1HDL A;  1IY6 A;  1CT2 I;  1KMA A;  2UZ3 A;  1IW4 A;  3BJI A;  2J9R A;  2QQE A;  3E2I A;  4B6D A;  5EX3 A;  2B8T A;  3HH2 C;  1CSO I;  1FYB A;  1M8B A;  1XA6 A;  2QQC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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