3UGLA

Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase c delta
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
65
structure length
65
Chain Sequence
GSRRASVGSHRFKVYNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCEFIVTD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta
pubmed doi rcsb
molecule tags Metal binding protein
source organism Mus musculus
molecule keywords Proteine kinase C delta type
total genus 11
structure length 65
sequence length 65
chains with identical sequence B
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2011-11-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.20 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 3uglA01
3BJIA 3UEYA 3UGIA 2VRWB 1TBNA 2E73A 2JA1A 4B6DA 2QQ0A 5FUWA 1RFHA 4UXHA 2QPOA 2J9RA 2J87A 4UXJA 1W4RA 2ENZA 2YUUA 2B8TA 2ORVA 2ROWA 4UXIA 2UZ3A 3KY9A 2GVIA 1Y8FA 3E2IA 4FKDA 5FUYA 3UGDA 2QQEA 2DB6A 2ELIA 2ORWA 3UEJA 1XBTA 4L9MA 5FUXA 3UGLA 5FUVA 3CXLA 3UFFA 1KBFA 1KBEA 1XA6A 1FARA 1PTRA 1XX6A 2FNFX 1TBOA 1PTQA 2ENNA 1R79A 2WVJA 1FAQA
chains in the Genus database with same CATH superfamily
3BJIA 3UEYA 2RIJA 2CJSC 2VRWB 4WP4A 3TJQA 3RU0A 1X74A 2ODDA 1HPTA 2F3CI 2N17A 4B6DA 5EX3A 4E1PA 2NU4I 3R5DA 1P9ZA 2QPOA 1P9GA 4UXJA 2DKVA 1ULNA 1LR9A 2JW6A 1Q9BA 1N13A 2ROWA 5J8CA 1TOTA 3B4VC 1H0ZA 2GVIA 3OXGA 1UVFA 3VDUA 2OD1A 1X4SA 1OMUA 2WCYA 1M8CA 2DB6A 1K7UA 2OZUA 2CWHA 4DNCA 3VDPA 2DIPA 2JZMA 1CT0I 3QTLD 2BUSA 1R0RI 5E3PA 5FUXA 2CWGA 2CWFA 2NU1I 3CXLA 3D00A 3QWPA 1KBEA 1WKXA 1XX6A 2NU0I 3OL0A 4JCVE 1PCEA 1SGEI 1Z7KB 2E5RA 2Y0MA 2LB7A 1WTJA 1FYBA 2GIVA 1W4RA 2SGQI 1SGYI 1NUBA 2JYYA 2M5XA 5HQ8A 3OVOA 3UGIA 1K7VA 2KMOA 3TO9A 1IY6A 2JA1A 4MPIA 3PDNA 2J9RA 5HI7A 3FC3A 1CT4I 1TGSI 2N52A 1UVGA 3SGQI 3TO6A 2QQCA 2K9HA 3E2IA 3TOBA 2W0TA 1Y1BA 2KMPA 2P6AC 3E59A 3UEJA 3VE5A 1V1IA 4L9MA 5J8FA 2LUYA 3UGLA 1XA6A 1PTRA 1W3SA 2GKTI 2V1CA 3FSXA 3GOXA 2ENNA 2GKVA 2N71A 1ULKA 2KMRA 2XRCA 2YQPA 1SGDI 3UOEA 2JXDA 1KMAA 1TBRR 1CSOI 1MJ9A 2GKRI 1M8BA 1YTPA 2E73A 4SGBI 5CCMA 2X3TA 1IW4A 1TIHA 1UUCA 2QQ0A 1RFHA 1UHAA 4UXHA 1V1HA 2WGCA 5DAEA 2X52A 2B8TA 2ORVA 2V1CC 4UXIA 2UZ3A 1SGNI 3QAHA 2KMQA 1OMTA 2QQEA 1TURA 2ORWA 3R5CA 1Y1CA 2SGEI 2N1AB 2SGFI 4OVOA 1LR8A 1OYVI 1HDLA 1ULMA 1SGQI 5FUVA 5EX0A 3R5BA 3UFFA 2OU2A 7WGAA 5CCLA 1FARA 1BUSA 1PPFI 5E3RA 1TBOA 1DS3I 1MT1A 1CGII 1AN1I 2B0UC 3HH2C 1R79A 3OXFA 3SEKC 5JHWC 1FAQA 2OVOA 3SGBI 1PJUA 4HGUA 5E3QA 1CE3A 1SGPI 2L7XA 2PQ8A 2QQDA 3FSYA 1TBNA 2RC4A 1VDDA 3MEKA 4AMLA 1HJAI 4GI3C 5FUWA 1FY7A 2V53A 1SGRI 1YU6C 1S20A 2ERWA 1K7TA 2J87A 2ENZA 2KCXA 2UVOA 2YUUA 1HEVA 2ARPF 3KY9A 1WGTA 4A24A 1LR7A 1OVOA 1Y8FA 2L8EA 1WGCA 4FKDA 5FUYA 3UGDA 1CHOI 1IY5A 1Z2IA 2ELIA 2NU3I 1MJAA 2LEOA 2NU2I 4E1RA 1DS2I 3TOAA 1XBTA 1MJBA 2SGDI 3R5AA 2SGPI 1BMOA 1KBFA 1NXUA 2A20A 2FNFX 1TBQR 3OXLA 1CT2I 1TUSA 3TO7A 9WGAA 1PTQA 1CGJI 2WVJA 1U5KA
chains in the Genus database with same CATH topology
3BJIA 3UEYA 2CJSC 2VRWB 3TJQA 3RU0A 1X74A 2ODDA 1HPTA 2F3CI 2N17A 4B6DA 5EX3A 4E1PA 2NU4I 2QPOA 4UXJA 1LR9A 2JW6A 1H0ZA 1N13A 2ROWA 1TOTA 3B4VC 2GVIA 3OXGA 1UVFA 3VDUA 2OD1A 1X4SA 1OMUA 2WCYA 1M8CA 2DB6A 3VDPA 2DIPA 2JZMA 1CT0I 3QTLD 2BUSA 1R0RI 5FUXA 2NU1I 3CXLA 3D00A 3QWPA 1KBEA 1XX6A 2NU0I 3OL0A 4JCVE 1PCEA 1SGEI 1Z7KB 2E5RA 1FYBA 1W4RA 2SGQI 1SGYI 1NUBA 2JYYA 2M5XA 5HQ8A 3OVOA 3UGIA 2KMOA 1IY6A 2JA1A 3PDNA 2J9RA 5HI7A 3FC3A 1CT4I 1TGSI 2N52A 1UVGA 3SGQI 2QQCA 2K9HA 3E2IA 2W0TA 1Y1BA 2KMPA 2P6AC 3E59A 3UEJA 3VE5A 1V1IA 4L9MA 2LUYA 3UGLA 1XA6A 1PTRA 1W3SA 2GKTI 2V1CA 3GOXA 2ENNA 2GKVA 2N71A 2KMRA 2XRCA 2YQPA 1SGDI 2JXDA 1KMAA 1TBRR 1CSOI 2GKRI 1M8BA 1YTPA 2E73A 4SGBI 5CCMA 1IW4A 1TIHA 1UUCA 2QQ0A 1RFHA 4UXHA 1V1HA 5DAEA 2B8TA 2ORVA 2V1CC 4UXIA 2UZ3A 1SGNI 2KMQA 1OMTA 2QQEA 1TURA 2ORWA 1Y1CA 2SGEI 2N1AB 2SGFI 4OVOA 1LR8A 1OYVI 1HDLA 1SGQI 5FUVA 5EX0A 3UFFA 1BUSA 5CCLA 1FARA 1PPFI 1TBOA 1DS3I 1MT1A 2B0UC 1AN1I 1CGII 3HH2C 1R79A 3OXFA 3SEKC 5JHWC 1FAQA 2OVOA 3SGBI 1PJUA 4HGUA 1CE3A 1SGPI 2L7XA 2QQDA 1TBNA 1VDDA 3MEKA 1HJAI 4GI3C 5FUWA 2V53A 1SGRI 1YU6C 2ERWA 2J87A 2KCXA 2ENZA 2YUUA 2ARPF 3KY9A 4A24A 1LR7A 1OVOA 1Y8FA 2L8EA 4FKDA 5FUYA 3UGDA 1IY5A 1CHOI 2ELIA 2NU3I 2LEOA 2NU2I 4E1RA 1DS2I 1XBTA 2SGDI 1KBFA 2SGPI 1BMOA 2A20A 2FNFX 1TBQR 3OXLA 1CT2I 1TUSA 1PTQA 1CGJI 2WVJA 1U5KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BJI A;  3UEY A;  3UGI A;  2VRW B;  1TBN A;  2E73 A;  2JA1 A;  4B6D A;  2QQ0 A;  5FUW A;  1RFH A;  4UXH A;  2QPO A;  2J9R A;  2J87 A;  4UXJ A;  1W4R A;  2ENZ A;  2YUU A;  2B8T A;  2ORV A;  2ROW A;  4UXI A;  2UZ3 A;  3KY9 A;  2GVI A;  1Y8F A;  3E2I A;  4FKD A;  5FUY A;  3UGD A;  2QQE A;  2DB6 A;  2ELI A;  2ORW A;  3UEJ A;  1XBT A;  4L9M A;  5FUX A;  3UGL A;  5FUV A;  3CXL A;  3UFF A;  1KBF A;  1KBE A;  1XA6 A;  1FAR A;  1PTR A;  1XX6 A;  2FNF X;  1TBO A;  1PTQ A;  2ENN A;  1R79 A;  2WVJ A;  1FAQ A; 
#chains in the Genus database with same CATH topology
 3BJI A;  3UEY A;  2RIJ A;  2CJS C;  2VRW B;  4WP4 A;  3TJQ A;  3RU0 A;  1X74 A;  2ODD A;  1HPT A;  2F3C I;  2N17 A;  4B6D A;  5EX3 A;  4E1P A;  2NU4 I;  3R5D A;  1P9Z A;  2QPO A;  1P9G A;  4UXJ A;  2DKV A;  1ULN A;  1LR9 A;  2JW6 A;  1Q9B A;  1N13 A;  2ROW A;  5J8C A;  1TOT A;  3B4V C;  1H0Z A;  2GVI A;  3OXG A;  1UVF A;  3VDU A;  2OD1 A;  1X4S A;  1OMU A;  2WCY A;  1M8C A;  2DB6 A;  1K7U A;  2OZU A;  2CWH A;  4DNC A;  3VDP A;  2DIP A;  2JZM A;  1CT0 I;  3QTL D;  2BUS A;  1R0R I;  5E3P A;  5FUX A;  2CWG A;  2CWF A;  2NU1 I;  3CXL A;  3D00 A;  3QWP A;  1KBE A;  1WKX A;  1XX6 A;  2NU0 I;  3OL0 A;  4JCV E;  1PCE A;  1SGE I;  1Z7K B;  2E5R A;  2Y0M A;  2LB7 A;  1WTJ A;  1FYB A;  2GIV A;  1W4R A;  2SGQ I;  1SGY I;  1NUB A;  2JYY A;  2M5X A;  5HQ8 A;  3OVO A;  3UGI A;  1K7V A;  2KMO A;  3TO9 A;  1IY6 A;  2JA1 A;  4MPI A;  3PDN A;  2J9R A;  5HI7 A;  3FC3 A;  1CT4 I;  1TGS I;  2N52 A;  1UVG A;  3SGQ I;  3TO6 A;  2QQC A;  2K9H A;  3E2I A;  3TOB A;  2W0T A;  1Y1B A;  2KMP A;  2P6A C;  3E59 A;  3UEJ A;  3VE5 A;  1V1I A;  4L9M A;  5J8F A;  2LUY A;  3UGL A;  1XA6 A;  1PTR A;  1W3S A;  2GKT I;  2V1C A;  3FSX A;  3GOX A;  2ENN A;  2GKV A;  2N71 A;  1ULK A;  2KMR A;  2XRC A;  2YQP A;  1SGD I;  3UOE A;  2JXD A;  1KMA A;  1TBR R;  1CSO I;  1MJ9 A;  2GKR I;  1M8B A;  1YTP A;  2E73 A;  4SGB I;  5CCM A;  2X3T A;  1IW4 A;  1TIH A;  1UUC A;  2QQ0 A;  1RFH A;  1UHA A;  4UXH A;  1V1H A;  2WGC A;  5DAE A;  2X52 A;  2B8T A;  2ORV A;  2V1C C;  4UXI A;  2UZ3 A;  1SGN I;  3QAH A;  2KMQ A;  1OMT A;  2QQE A;  1TUR A;  2ORW A;  3R5C A;  1Y1C A;  2SGE I;  2N1A B;  2SGF I;  4OVO A;  1LR8 A;  1OYV I;  1HDL A;  1ULM A;  1SGQ I;  5FUV A;  5EX0 A;  3R5B A;  3UFF A;  2OU2 A;  7WGA A;  5CCL A;  1FAR A;  1BUS A;  1PPF I;  5E3R A;  1TBO A;  1DS3 I;  1MT1 A;  1CGI I;  1AN1 I;  2B0U C;  3HH2 C;  1R79 A;  3OXF A;  3SEK C;  5JHW C;  1FAQ A;  2OVO A;  3SGB I;  1PJU A;  4HGU A;  5E3Q A;  1CE3 A;  1SGP I;  2L7X A;  2PQ8 A;  2QQD A;  3FSY A;  1TBN A;  2RC4 A;  1VDD A;  3MEK A;  4AML A;  1HJA I;  4GI3 C;  5FUW A;  1FY7 A;  2V53 A;  1SGR I;  1YU6 C;  1S20 A;  2ERW A;  1K7T A;  2J87 A;  2ENZ A;  2KCX A;  2UVO A;  2YUU A;  1HEV A;  2ARP F;  3KY9 A;  1WGT A;  4A24 A;  1LR7 A;  1OVO A;  1Y8F A;  2L8E A;  1WGC A;  4FKD A;  5FUY A;  3UGD A;  1CHO I;  1IY5 A;  1Z2I A;  2ELI A;  2NU3 I;  1MJA A;  2LEO A;  2NU2 I;  4E1R A;  1DS2 I;  3TOA A;  1XBT A;  1MJB A;  2SGD I;  3R5A A;  2SGP I;  1BMO A;  1KBF A;  1NXU A;  2A20 A;  2FNF X;  1TBQ R;  3OXL A;  1CT2 I;  1TUS A;  3TO7 A;  9WGA A;  1PTQ A;  1CGJ I;  2WVJ A;  1U5K A; 
#chains in the Genus database with same CATH homology
 3BJI A;  3UEY A;  2CJS C;  2VRW B;  3TJQ A;  3RU0 A;  1X74 A;  2ODD A;  1HPT A;  2F3C I;  2N17 A;  4B6D A;  5EX3 A;  4E1P A;  2NU4 I;  2QPO A;  4UXJ A;  1LR9 A;  2JW6 A;  1H0Z A;  1N13 A;  2ROW A;  1TOT A;  3B4V C;  2GVI A;  3OXG A;  1UVF A;  3VDU A;  2OD1 A;  1X4S A;  1OMU A;  2WCY A;  1M8C A;  2DB6 A;  3VDP A;  2DIP A;  2JZM A;  1CT0 I;  3QTL D;  2BUS A;  1R0R I;  5FUX A;  2NU1 I;  3CXL A;  3D00 A;  3QWP A;  1KBE A;  1XX6 A;  2NU0 I;  3OL0 A;  4JCV E;  1PCE A;  1SGE I;  1Z7K B;  2E5R A;  1FYB A;  1W4R A;  2SGQ I;  1SGY I;  1NUB A;  2JYY A;  2M5X A;  5HQ8 A;  3OVO A;  3UGI A;  2KMO A;  1IY6 A;  2JA1 A;  3PDN A;  2J9R A;  5HI7 A;  3FC3 A;  1CT4 I;  1TGS I;  2N52 A;  1UVG A;  3SGQ I;  2QQC A;  2K9H A;  3E2I A;  2W0T A;  1Y1B A;  2KMP A;  2P6A C;  3E59 A;  3UEJ A;  3VE5 A;  1V1I A;  4L9M A;  2LUY A;  3UGL A;  1XA6 A;  1PTR A;  1W3S A;  2GKT I;  2V1C A;  3GOX A;  2ENN A;  2GKV A;  2N71 A;  2KMR A;  2XRC A;  2YQP A;  1SGD I;  2JXD A;  1KMA A;  1TBR R;  1CSO I;  2GKR I;  1M8B A;  1YTP A;  2E73 A;  4SGB I;  5CCM A;  1IW4 A;  1TIH A;  1UUC A;  2QQ0 A;  1RFH A;  4UXH A;  1V1H A;  5DAE A;  2B8T A;  2ORV A;  2V1C C;  4UXI A;  2UZ3 A;  1SGN I;  2KMQ A;  1OMT A;  2QQE A;  1TUR A;  2ORW A;  1Y1C A;  2SGE I;  2N1A B;  2SGF I;  4OVO A;  1LR8 A;  1OYV I;  1HDL A;  1SGQ I;  5FUV A;  5EX0 A;  3UFF A;  1BUS A;  5CCL A;  1FAR A;  1PPF I;  1TBO A;  1DS3 I;  1MT1 A;  2B0U C;  1AN1 I;  1CGI I;  3HH2 C;  1R79 A;  3OXF A;  3SEK C;  5JHW C;  1FAQ A;  2OVO A;  3SGB I;  1PJU A;  4HGU A;  1CE3 A;  1SGP I;  2L7X A;  2QQD A;  1TBN A;  1VDD A;  3MEK A;  1HJA I;  4GI3 C;  5FUW A;  2V53 A;  1SGR I;  1YU6 C;  2ERW A;  2J87 A;  2KCX A;  2ENZ A;  2YUU A;  2ARP F;  3KY9 A;  4A24 A;  1LR7 A;  1OVO A;  1Y8F A;  2L8E A;  4FKD A;  5FUY A;  3UGD A;  1IY5 A;  1CHO I;  2ELI A;  2NU3 I;  2LEO A;  2NU2 I;  4E1R A;  1DS2 I;  1XBT A;  2SGD I;  1KBF A;  2SGP I;  1BMO A;  2A20 A;  2FNF X;  1TBQ R;  3OXL A;  1CT2 I;  1TUS A;  1PTQ A;  1CGJ I;  2WVJ A;  1U5K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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