4B6DA

Structure of the atypical c1 domain of mgcracgap
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
60
structure length
60
Chain Sequence
GPLGSMRLHDFVSKTVIKPESCVPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Centralspindlin Links the Mitotic Spindle to the Plasma Membrane During Cytokinesis.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords RAC GTPASE-ACTIVATING PROTEIN 1
total genus 10
structure length 60
sequence length 60
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2012-08-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00130 C1_1 Phorbol esters/diacylglycerol binding domain (C1 domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.20 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 4b6dA00
2E73A 1PTRA 3UGDA 3BJIA 1XBTA 2ROWA 1FAQA 4FKDA 1XX6A 4B6DA 2QPOA 2QQ0A 1PTQA 2JA1A 3UGIA 1TBOA 2ENNA 2FNFX 4L9MA 5FUYA 2ELIA 5FUVA 2QQEA 2GVIA 1W4RA 3UFFA 2YUUA 4UXJA 3UGLA 2J87A 1FARA 3UEJA 3KY9A 2ENZA 2ORVA 2DB6A 3E2IA 2UZ3A 1XA6A 1KBEA 1R79A 2B8TA 2ORWA 2VRWB 2WVJA 1TBNA 3CXLA 4UXHA 5FUWA 4UXIA 3UEYA 5FUXA 1KBFA 1RFHA 1Y8FA 2J9RA
chains in the Genus database with same CATH superfamily
2E73A 3UGDA 3TOAA 3OXGA 1XBTA 1SGYI 2N1AB 2OZUA 2ROWA 3OVOA 1CGJI 2CWHA 1U5KA 1PPFI 4A24A 4B6DA 5J8CA 2W0TA 4AMLA 2L8EA 2CJSC 1WTJA 5CCMA 1NUBA 3UGIA 2GKRI 1KMAA 1SGNI 2ENNA 1H0ZA 5J8FA 1BUSA 4L9MA 1WGTA 1SGEI 2LUYA 1AN1I 2RIJA 2GVIA 3MEKA 1W4RA 1K7VA 1K7UA 1UHAA 2X52A 2OVOA 2CWFA 3R5BA 1CT0I 1DS3I 3TO6A 5E3QA 1Z7KB 1S20A 2LEOA 1R79A 2WVJA 2ORWA 3CXLA 3OXLA 1V1IA 2L7XA 5EX3A 3SGBI 4UXIA 1HJAI 5FUXA 3UEYA 1RFHA 2E5RA 3VDUA 2GKVA 3E59A 3UOEA 1TOTA 1LR9A 3BJIA 2SGPI 3QWPA 2NU2I 1TBRR 1WGCA 2QPOA 3VDPA 1M8BA 2WGCA 1SGPI 2V1CA 1CGII 2SGEI 4E1RA 3TO7A 2XRCA 2SGQI 2ODDA 1N13A 1ULMA 1LR8A 1TBQR 1X4SA 5HI7A 2N71A 5DAEA 5FUVA 3TJQA 4WP4A 1TIHA 1BMOA 1R0RI 1SGDI 1OMUA 3UFFA 1TGSI 2RC4A 2YUUA 1V1HA 2SGFI 2P6AC 1UUCA 3UGLA 2J87A 1FARA 1VDDA 2X3TA 5E3PA 3UEJA 2WCYA 2KMPA 2ENZA 3RU0A 5EX0A 1ULKA 1CHOI 3SEKC 1XA6A 2B8TA 1TURA 1SGQI 1TBNA 3TO9A 7WGAA 1Z2IA 2OU2A 2NU0I 4HGUA 1KBFA 2OD1A 1PTQA 1Y8FA 2KCXA 2V53A 1PCEA 2Y0MA 3HH2C 1PTRA 1UVFA 1WKXA 1Y1BA 4JCVE 1XX6A 1FAQA 4GI3C 2QQDA 3OXFA 2JA1A 4MPIA 1P9GA 2YQPA 1K7TA 2LB7A 1TBOA 2DIPA 3QTLD 1IY5A 2FNFX 2V1CC 2N52A 3D00A 1LR7A 2ERWA 2JXDA 3R5DA 3SGQI 4OVOA 2UVOA 5E3RA 1CSOI 1HPTA 3PDNA 2M5XA 9WGAA 4SGBI 4UXJA 2KMQA 2F3CI 4DNCA 3FSYA 3KY9A 3E2IA 3R5AA 3B4VC 3R5CA 3FSXA 5HQ8A 2VRWB 1ULNA 1TUSA 5FUWA 2JYYA 2BUSA 1CT2I 2NU1I 2QQCA 1MJAA 3TOBA 2PQ8A 2SGDI 4FKDA 1UVGA 5JHWC 1MT1A 2A20A 2JZMA 1OMTA 1X74A 1IY6A 2QQ0A 2JW6A 1M8CA 2N17A 1Y1CA 1SGRI 2K9HA 2KMRA 3GOXA 1Q9BA 1OYVI 2NU4I 1MJ9A 1IW4A 1DS2I 1P9ZA 2GKTI 2KMOA 2NU3I 5FUYA 2ARPF 1MJBA 2DKVA 2ELIA 3QAHA 3FC3A 2QQEA 1OVOA 4E1PA 1FYBA 2B0UC 1PJUA 5CCLA 2CWGA 2GIVA 1FY7A 2ORVA 2DB6A 1CE3A 1W3SA 2UZ3A 3VE5A 1KBEA 1CT4I 1YTPA 3OL0A 4UXHA 1NXUA 1HDLA 1HEVA 1YU6C 2J9RA
chains in the Genus database with same CATH topology
2E73A 3UGDA 3OXGA 1XBTA 1SGYI 2N1AB 2ROWA 3OVOA 4A24A 1CGJI 1U5KA 1PPFI 4B6DA 2W0TA 2L8EA 2CJSC 5CCMA 1NUBA 3UGIA 2GKRI 1KMAA 1SGNI 2ENNA 1H0ZA 1BUSA 4L9MA 1SGEI 2LUYA 1AN1I 2GVIA 3MEKA 1W4RA 2OVOA 1CT0I 1DS3I 1Z7KB 2WVJA 2LEOA 1R79A 2ORWA 3CXLA 3OXLA 1V1IA 2L7XA 5EX3A 3SGBI 4UXIA 1HJAI 5FUXA 3UEYA 1RFHA 2E5RA 3VDUA 2GKVA 3E59A 1TOTA 1LR9A 3BJIA 2SGPI 3QWPA 2NU2I 1TBRR 2QPOA 3VDPA 1M8BA 1SGPI 2V1CA 1CGII 2SGEI 4E1RA 2XRCA 2SGQI 2ODDA 1N13A 1LR8A 1TBQR 1X4SA 5HI7A 2N71A 5DAEA 5FUVA 3TJQA 1TIHA 1BMOA 1R0RI 1SGDI 1OMUA 3UFFA 1TGSI 2YUUA 1V1HA 2SGFI 2P6AC 1UUCA 3UGLA 2J87A 1FARA 1VDDA 3UEJA 2WCYA 2KMPA 2ENZA 3RU0A 5EX0A 1CHOI 3SEKC 1XA6A 2B8TA 1TURA 1SGQI 1TBNA 2NU0I 4HGUA 1KBFA 2OD1A 1Y8FA 1PTQA 2KCXA 2V53A 1PCEA 3HH2C 1PTRA 1UVFA 1Y1BA 4JCVE 1XX6A 1FAQA 4GI3C 2QQDA 3OXFA 2JA1A 2YQPA 1TBOA 2DIPA 3QTLD 1IY5A 2FNFX 2V1CC 2N52A 3D00A 1LR7A 2ERWA 2JXDA 3SGQI 4OVOA 1CSOI 1HPTA 3PDNA 2M5XA 4SGBI 4UXJA 2KMQA 2F3CI 3KY9A 3E2IA 3B4VC 5HQ8A 2VRWB 1TUSA 5FUWA 2JYYA 2BUSA 1CT2I 2NU1I 2QQCA 2SGDI 4FKDA 1UVGA 5JHWC 1MT1A 2A20A 2JZMA 1OMTA 1X74A 1IY6A 2QQ0A 2JW6A 1M8CA 2N17A 1Y1CA 1SGRI 2K9HA 2KMRA 3GOXA 1OYVI 2NU4I 1IW4A 1DS2I 2GKTI 2KMOA 2NU3I 5FUYA 2ARPF 2ELIA 3FC3A 2QQEA 1OVOA 4E1PA 1FYBA 2B0UC 1PJUA 5CCLA 2ORVA 2DB6A 1CE3A 1W3SA 2UZ3A 3VE5A 1KBEA 1CT4I 1YTPA 3OL0A 4UXHA 1HDLA 1YU6C 2J9RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E73 A;  1PTR A;  3UGD A;  3BJI A;  1XBT A;  2ROW A;  1FAQ A;  4FKD A;  1XX6 A;  4B6D A;  2QPO A;  2QQ0 A;  1PTQ A;  2JA1 A;  3UGI A;  1TBO A;  2ENN A;  2FNF X;  4L9M A;  5FUY A;  2ELI A;  5FUV A;  2QQE A;  2GVI A;  1W4R A;  3UFF A;  2YUU A;  4UXJ A;  3UGL A;  2J87 A;  1FAR A;  3UEJ A;  3KY9 A;  2ENZ A;  2ORV A;  2DB6 A;  3E2I A;  2UZ3 A;  1XA6 A;  1KBE A;  1R79 A;  2B8T A;  2ORW A;  2VRW B;  2WVJ A;  1TBN A;  3CXL A;  4UXH A;  5FUW A;  4UXI A;  3UEY A;  5FUX A;  1KBF A;  1RFH A;  1Y8F A;  2J9R A; 
#chains in the Genus database with same CATH topology
 2E73 A;  3UGD A;  3TOA A;  3OXG A;  1XBT A;  1SGY I;  2N1A B;  2OZU A;  2ROW A;  3OVO A;  1CGJ I;  2CWH A;  1U5K A;  1PPF I;  4A24 A;  4B6D A;  5J8C A;  2W0T A;  4AML A;  2L8E A;  2CJS C;  1WTJ A;  5CCM A;  1NUB A;  3UGI A;  2GKR I;  1KMA A;  1SGN I;  2ENN A;  1H0Z A;  5J8F A;  1BUS A;  4L9M A;  1WGT A;  1SGE I;  2LUY A;  1AN1 I;  2RIJ A;  2GVI A;  3MEK A;  1W4R A;  1K7V A;  1K7U A;  1UHA A;  2X52 A;  2OVO A;  2CWF A;  3R5B A;  1CT0 I;  1DS3 I;  3TO6 A;  5E3Q A;  1Z7K B;  1S20 A;  2LEO A;  1R79 A;  2WVJ A;  2ORW A;  3CXL A;  3OXL A;  1V1I A;  2L7X A;  5EX3 A;  3SGB I;  4UXI A;  1HJA I;  5FUX A;  3UEY A;  1RFH A;  2E5R A;  3VDU A;  2GKV A;  3E59 A;  3UOE A;  1TOT A;  1LR9 A;  3BJI A;  2SGP I;  3QWP A;  2NU2 I;  1TBR R;  1WGC A;  2QPO A;  3VDP A;  1M8B A;  2WGC A;  1SGP I;  2V1C A;  1CGI I;  2SGE I;  4E1R A;  3TO7 A;  2XRC A;  2SGQ I;  2ODD A;  1N13 A;  1ULM A;  1LR8 A;  1TBQ R;  1X4S A;  5HI7 A;  2N71 A;  5DAE A;  5FUV A;  3TJQ A;  4WP4 A;  1TIH A;  1BMO A;  1R0R I;  1SGD I;  1OMU A;  3UFF A;  1TGS I;  2RC4 A;  2YUU A;  1V1H A;  2SGF I;  2P6A C;  1UUC A;  3UGL A;  2J87 A;  1FAR A;  1VDD A;  2X3T A;  5E3P A;  3UEJ A;  2WCY A;  2KMP A;  2ENZ A;  3RU0 A;  5EX0 A;  1ULK A;  1CHO I;  3SEK C;  1XA6 A;  2B8T A;  1TUR A;  1SGQ I;  1TBN A;  3TO9 A;  7WGA A;  1Z2I A;  2OU2 A;  2NU0 I;  4HGU A;  1KBF A;  2OD1 A;  1PTQ A;  1Y8F A;  2KCX A;  2V53 A;  1PCE A;  2Y0M A;  3HH2 C;  1PTR A;  1UVF A;  1WKX A;  1Y1B A;  4JCV E;  1XX6 A;  1FAQ A;  4GI3 C;  2QQD A;  3OXF A;  2JA1 A;  4MPI A;  1P9G A;  2YQP A;  1K7T A;  2LB7 A;  1TBO A;  2DIP A;  3QTL D;  1IY5 A;  2FNF X;  2V1C C;  2N52 A;  3D00 A;  1LR7 A;  2ERW A;  2JXD A;  3R5D A;  3SGQ I;  4OVO A;  2UVO A;  5E3R A;  1CSO I;  1HPT A;  3PDN A;  2M5X A;  9WGA A;  4SGB I;  4UXJ A;  2KMQ A;  2F3C I;  4DNC A;  3FSY A;  3KY9 A;  3E2I A;  3R5A A;  3B4V C;  3R5C A;  3FSX A;  5HQ8 A;  2VRW B;  1ULN A;  1TUS A;  5FUW A;  2JYY A;  2BUS A;  1CT2 I;  2NU1 I;  2QQC A;  1MJA A;  3TOB A;  2PQ8 A;  2SGD I;  4FKD A;  1UVG A;  5JHW C;  1MT1 A;  2A20 A;  2JZM A;  1OMT A;  1X74 A;  1IY6 A;  2QQ0 A;  2JW6 A;  1M8C A;  2N17 A;  1Y1C A;  1SGR I;  2K9H A;  2KMR A;  3GOX A;  1Q9B A;  1OYV I;  2NU4 I;  1MJ9 A;  1IW4 A;  1DS2 I;  1P9Z A;  2GKT I;  2KMO A;  2NU3 I;  5FUY A;  2ARP F;  1MJB A;  2DKV A;  2ELI A;  3QAH A;  3FC3 A;  2QQE A;  1OVO A;  4E1P A;  1FYB A;  2B0U C;  1PJU A;  5CCL A;  2CWG A;  2GIV A;  1FY7 A;  2ORV A;  2DB6 A;  1CE3 A;  1W3S A;  2UZ3 A;  3VE5 A;  1KBE A;  1CT4 I;  1YTP A;  3OL0 A;  4UXH A;  1NXU A;  1HDL A;  1HEV A;  1YU6 C;  2J9R A; 
#chains in the Genus database with same CATH homology
 2E73 A;  3UGD A;  3OXG A;  1XBT A;  1SGY I;  2N1A B;  2ROW A;  3OVO A;  4A24 A;  1CGJ I;  1U5K A;  1PPF I;  4B6D A;  2W0T A;  2L8E A;  2CJS C;  5CCM A;  1NUB A;  3UGI A;  2GKR I;  1KMA A;  1SGN I;  2ENN A;  1H0Z A;  1BUS A;  4L9M A;  1SGE I;  2LUY A;  1AN1 I;  2GVI A;  3MEK A;  1W4R A;  2OVO A;  1CT0 I;  1DS3 I;  1Z7K B;  2WVJ A;  2LEO A;  1R79 A;  2ORW A;  3CXL A;  3OXL A;  1V1I A;  2L7X A;  5EX3 A;  3SGB I;  4UXI A;  1HJA I;  5FUX A;  3UEY A;  1RFH A;  2E5R A;  3VDU A;  2GKV A;  3E59 A;  1TOT A;  1LR9 A;  3BJI A;  2SGP I;  3QWP A;  2NU2 I;  1TBR R;  2QPO A;  3VDP A;  1M8B A;  1SGP I;  2V1C A;  1CGI I;  2SGE I;  4E1R A;  2XRC A;  2SGQ I;  2ODD A;  1N13 A;  1LR8 A;  1TBQ R;  1X4S A;  5HI7 A;  2N71 A;  5DAE A;  5FUV A;  3TJQ A;  1TIH A;  1BMO A;  1R0R I;  1SGD I;  1OMU A;  3UFF A;  1TGS I;  2YUU A;  1V1H A;  2SGF I;  2P6A C;  1UUC A;  3UGL A;  2J87 A;  1FAR A;  1VDD A;  3UEJ A;  2WCY A;  2KMP A;  2ENZ A;  3RU0 A;  5EX0 A;  1CHO I;  3SEK C;  1XA6 A;  2B8T A;  1TUR A;  1SGQ I;  1TBN A;  2NU0 I;  4HGU A;  1KBF A;  2OD1 A;  1Y8F A;  1PTQ A;  2KCX A;  2V53 A;  1PCE A;  3HH2 C;  1PTR A;  1UVF A;  1Y1B A;  4JCV E;  1XX6 A;  1FAQ A;  4GI3 C;  2QQD A;  3OXF A;  2JA1 A;  2YQP A;  1TBO A;  2DIP A;  3QTL D;  1IY5 A;  2FNF X;  2V1C C;  2N52 A;  3D00 A;  1LR7 A;  2ERW A;  2JXD A;  3SGQ I;  4OVO A;  1CSO I;  1HPT A;  3PDN A;  2M5X A;  4SGB I;  4UXJ A;  2KMQ A;  2F3C I;  3KY9 A;  3E2I A;  3B4V C;  5HQ8 A;  2VRW B;  1TUS A;  5FUW A;  2JYY A;  2BUS A;  1CT2 I;  2NU1 I;  2QQC A;  2SGD I;  4FKD A;  1UVG A;  5JHW C;  1MT1 A;  2A20 A;  2JZM A;  1OMT A;  1X74 A;  1IY6 A;  2QQ0 A;  2JW6 A;  1M8C A;  2N17 A;  1Y1C A;  1SGR I;  2K9H A;  2KMR A;  3GOX A;  1OYV I;  2NU4 I;  1IW4 A;  1DS2 I;  2GKT I;  2KMO A;  2NU3 I;  5FUY A;  2ARP F;  2ELI A;  3FC3 A;  2QQE A;  1OVO A;  4E1P A;  1FYB A;  2B0U C;  1PJU A;  5CCL A;  2ORV A;  2DB6 A;  1CE3 A;  1W3S A;  2UZ3 A;  3VE5 A;  1KBE A;  1CT4 I;  1YTP A;  3OL0 A;  4UXH A;  1HDL A;  1YU6 C;  2J9R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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