4B6DA

Structure of the atypical c1 domain of mgcracgap
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
60
structure length
60
Chain Sequence
GPLGSMRLHDFVSKTVIKPESCVPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Centralspindlin Links the Mitotic Spindle to the Plasma Membrane During Cytokinesis.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords RAC GTPASE-ACTIVATING PROTEIN 1
total genus 10
structure length 60
sequence length 60
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2012-08-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00130 C1_1 Phorbol esters/diacylglycerol binding domain (C1 domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.20 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 4b6dA00
2UZ3A 4L9MA 2GVIA 1XX6A 1KBEA 1KBFA 1XA6A 2WVJA 3UGIA 5FUWA 2J87A 3UFFA 1RFHA 1R79A 2JA1A 3UEJA 2QQ0A 2YUUA 2ELIA 2J9RA 3E2IA 1PTRA 5FUYA 1W4RA 5FUVA 3KY9A 2ROWA 1Y8FA 2VRWB 1TBOA 2ORWA 4UXHA 1FAQA 1TBNA 2E73A 4UXIA 5FUXA 2ENNA 2B8TA 2QPOA 4FKDA 3CXLA 3UGLA 1FARA 1XBTA 2ENZA 4B6DA 3BJIA 3UEYA 2ORVA 4UXJA 3UGDA 2FNFX 2QQEA 1PTQA 2DB6A
chains in the Genus database with same CATH superfamily
2NU4I 4L9MA 3B4VC 1WKXA 1XA6A 2OD1A 3D00A 2V53A 5DAEA 3UFFA 2CWGA 3FC3A 1P9ZA 2JA1A 2SGDI 3UEJA 2Y0MA 2LEOA 3E2IA 1VDDA 2QQDA 4DNCA 3OL0A 1X4SA 2XRCA 1M8BA 5E3PA 1W4RA 4E1PA 1BMOA 2N1AB 5HQ8A 2BUSA 1BUSA 3KY9A 2V1CA 1K7TA 2VRWB 1TBOA 1AN1I 2ORWA 1SGPI 4UXHA 1IY5A 1SGEI 1UHAA 4UXIA 2L8EA 2B8TA 1YTPA 1S20A 2ODDA 2NU1I 3QAHA 3CXLA 3UOEA 2N17A 2JW6A 2SGPI 3R5BA 2JZMA 2GIVA 3BJIA 1HEVA 1SGNI 1LR9A 2OVOA 3TO9A 2QQEA 1PJUA 1KBEA 1Y1CA 1ULMA 1TOTA 2F3CI 2GVIA 2RC4A 3VE5A 1LR8A 3TO7A 1KBFA 1ULKA 2SGEI 4AMLA 3E59A 2DKVA 2J87A 1R0RI 5FUWA 1R79A 3QWPA 3VDUA 1MJ9A 1K7VA 1FYBA 1V1IA 2DIPA 2QQ0A 2ELIA 2CJSC 1NUBA 2J9RA 2M5XA 3OXLA 2KMPA 3SGBI 5FUYA 2NU2I 1CGII 5CCMA 1CSOI 1DS3I 1UUCA 1CT2I 1SGYI 3PDNA 2ENNA 3SEKC 1CE3A 2JYYA 1U5KA 3TO6A 1MT1A 2OU2A 4FKDA 3UGLA 1IY6A 1OYVI 1WGTA 3HH2C 3MEKA 4OVOA 2KMQA 4B6DA 1NXUA 2ORVA 3FSYA 3UGDA 2FNFX 1KMAA 3SGQI 1PTQA 1PCEA 4MPIA 2N52A 3VDPA 1P9GA 2LUYA 2UVOA 1ULNA 5CCLA 1TBRR 1HDLA 2P6AC 2GKTI 2X52A 2JXDA 1YU6C 1CT4I 1Q9BA 1RFHA 2CWHA 3R5AA 7WGAA 3TOAA 2CWFA 2L7XA 2QQCA 1CT0I 3RU0A 1UVGA 1PTRA 1CGJI 2SGFI 1N13A 2B0UC 5FUVA 1MJAA 1TGSI 1OVOA 1WTJA 2ROWA 1Y8FA 2E5RA 4WP4A 1IW4A 1FAQA 3OVOA 1TUSA 5HI7A 1LR7A 1DS2I 2E73A 5FUXA 5JHWC 1Z2IA 1Z7KB 5J8CA 1K7UA 2QPOA 2NU0I 9WGAA 2W0TA 1OMUA 1Y1BA 5E3QA 5J8FA 2NU3I 1SGDI 2GKVA 3GOXA 1FARA 1UVFA 2GKRI 1H0ZA 3UEYA 4UXJA 1SGQI 2ARPF 4HGUA 1MJBA 4JCVE 1FY7A 2WCYA 4E1RA 1HJAI 2DB6A 2UZ3A 1CHOI 1OMTA 1XX6A 2KMOA 3FSXA 1WGCA 2A20A 1TBQR 5EX0A 2WVJA 3UGIA 4SGBI 3R5CA 2ERWA 1V1HA 2YUUA 5E3RA 3TOBA 1PPFI 2X3TA 3TJQA 2RIJA 2K9HA 1TIHA 5EX3A 1X74A 2PQ8A 3OXFA 1TBNA 4A24A 1TURA 2LB7A 2V1CC 3QTLD 4GI3C 3OXGA 2KCXA 1SGRI 2WGCA 2YQPA 1XBTA 1M8CA 2ENZA 2KMRA 1W3SA 2N71A 2SGQI 2OZUA 3R5DA 1HPTA
chains in the Genus database with same CATH topology
2NU4I 4L9MA 3B4VC 1XA6A 2OD1A 3D00A 2V53A 5DAEA 3UFFA 3FC3A 2JA1A 2SGDI 3UEJA 2LEOA 3E2IA 1VDDA 2QQDA 3OL0A 1X4SA 2XRCA 1M8BA 1W4RA 4E1PA 1BMOA 2N1AB 5HQ8A 2BUSA 1BUSA 3KY9A 2V1CA 1IY5A 2VRWB 1TBOA 1AN1I 2ORWA 1SGPI 4UXHA 1SGEI 4UXIA 2L8EA 2B8TA 1YTPA 2ODDA 2NU1I 3CXLA 2N17A 2JW6A 2SGPI 2JZMA 3BJIA 1SGNI 1LR9A 2OVOA 2QQEA 1Y1CA 1KBEA 1PJUA 2F3CI 1TOTA 2GVIA 3VE5A 1LR8A 1KBFA 2SGEI 3E59A 5FUWA 2J87A 1R0RI 3VDUA 1R79A 3QWPA 1FYBA 1V1IA 2DIPA 2QQ0A 2ELIA 2CJSC 1NUBA 2J9RA 2M5XA 3OXLA 2KMPA 3SGBI 5FUYA 2NU2I 1CGII 5CCMA 1CSOI 1DS3I 1UUCA 1CT2I 1SGYI 3PDNA 2ENNA 3SEKC 1CE3A 2JYYA 1U5KA 1MT1A 4FKDA 3UGLA 1IY6A 1OYVI 3HH2C 3MEKA 4OVOA 2KMQA 4B6DA 2ORVA 3UGDA 2FNFX 1KMAA 3SGQI 1PTQA 1PCEA 2N52A 3VDPA 2LUYA 5CCLA 1TBRR 1HDLA 2P6AC 2GKTI 2JXDA 1YU6C 1CT4I 1RFHA 2L7XA 2QQCA 1CT0I 3RU0A 1UVGA 1PTRA 1CGJI 2SGFI 1N13A 2B0UC 5FUVA 1TGSI 1OVOA 2ROWA 1IW4A 1Y8FA 2E5RA 1FAQA 3OVOA 1TUSA 5HI7A 1LR7A 1DS2I 2E73A 5FUXA 5JHWC 1Z7KB 2QPOA 2NU0I 2W0TA 1OMUA 1Y1BA 2NU3I 1SGDI 2GKVA 3GOXA 1FARA 1UVFA 2GKRI 1H0ZA 3UEYA 4UXJA 1SGQI 2ARPF 4HGUA 4JCVE 2WCYA 4E1RA 1HJAI 2DB6A 2UZ3A 1CHOI 1OMTA 1XX6A 2KMOA 5EX0A 2A20A 1TBQR 2WVJA 3UGIA 4SGBI 2ERWA 1V1HA 2YUUA 1PPFI 3TJQA 2K9HA 1TIHA 5EX3A 1X74A 3OXFA 1TBNA 4A24A 1TURA 2V1CC 3QTLD 4GI3C 3OXGA 2KCXA 1SGRI 2YQPA 1XBTA 1M8CA 2ENZA 2KMRA 1W3SA 2N71A 2SGQI 1HPTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2UZ3 A;  4L9M A;  2GVI A;  1XX6 A;  1KBE A;  1KBF A;  1XA6 A;  2WVJ A;  3UGI A;  5FUW A;  2J87 A;  3UFF A;  1RFH A;  1R79 A;  2JA1 A;  3UEJ A;  2QQ0 A;  2YUU A;  2ELI A;  2J9R A;  3E2I A;  1PTR A;  5FUY A;  1W4R A;  5FUV A;  3KY9 A;  2ROW A;  1Y8F A;  2VRW B;  1TBO A;  2ORW A;  4UXH A;  1FAQ A;  1TBN A;  2E73 A;  4UXI A;  5FUX A;  2ENN A;  2B8T A;  2QPO A;  4FKD A;  3CXL A;  3UGL A;  1FAR A;  1XBT A;  2ENZ A;  4B6D A;  3BJI A;  3UEY A;  2ORV A;  4UXJ A;  3UGD A;  2FNF X;  2QQE A;  1PTQ A;  2DB6 A; 
#chains in the Genus database with same CATH topology
 2NU4 I;  4L9M A;  3B4V C;  1WKX A;  1XA6 A;  2OD1 A;  3D00 A;  2V53 A;  5DAE A;  3UFF A;  2CWG A;  3FC3 A;  1P9Z A;  2JA1 A;  2SGD I;  3UEJ A;  2Y0M A;  2LEO A;  3E2I A;  1VDD A;  2QQD A;  4DNC A;  3OL0 A;  1X4S A;  2XRC A;  1M8B A;  5E3P A;  1W4R A;  4E1P A;  1BMO A;  2N1A B;  5HQ8 A;  2BUS A;  1BUS A;  3KY9 A;  2V1C A;  1K7T A;  2VRW B;  1TBO A;  1AN1 I;  2ORW A;  1SGP I;  4UXH A;  1IY5 A;  1SGE I;  1UHA A;  4UXI A;  2L8E A;  2B8T A;  1YTP A;  1S20 A;  2ODD A;  2NU1 I;  3QAH A;  3CXL A;  3UOE A;  2N17 A;  2JW6 A;  2SGP I;  3R5B A;  2JZM A;  2GIV A;  3BJI A;  1HEV A;  1SGN I;  1LR9 A;  2OVO A;  3TO9 A;  2QQE A;  1PJU A;  1KBE A;  1Y1C A;  1ULM A;  1TOT A;  2F3C I;  2GVI A;  2RC4 A;  3VE5 A;  1LR8 A;  3TO7 A;  1KBF A;  1ULK A;  2SGE I;  4AML A;  3E59 A;  2DKV A;  2J87 A;  1R0R I;  5FUW A;  1R79 A;  3QWP A;  3VDU A;  1MJ9 A;  1K7V A;  1FYB A;  1V1I A;  2DIP A;  2QQ0 A;  2ELI A;  2CJS C;  1NUB A;  2J9R A;  2M5X A;  3OXL A;  2KMP A;  3SGB I;  5FUY A;  2NU2 I;  1CGI I;  5CCM A;  1CSO I;  1DS3 I;  1UUC A;  1CT2 I;  1SGY I;  3PDN A;  2ENN A;  3SEK C;  1CE3 A;  2JYY A;  1U5K A;  3TO6 A;  1MT1 A;  2OU2 A;  4FKD A;  3UGL A;  1IY6 A;  1OYV I;  1WGT A;  3HH2 C;  3MEK A;  4OVO A;  2KMQ A;  4B6D A;  1NXU A;  2ORV A;  3FSY A;  3UGD A;  2FNF X;  1KMA A;  3SGQ I;  1PTQ A;  1PCE A;  4MPI A;  2N52 A;  3VDP A;  1P9G A;  2LUY A;  2UVO A;  1ULN A;  5CCL A;  1TBR R;  1HDL A;  2P6A C;  2GKT I;  2X52 A;  2JXD A;  1YU6 C;  1CT4 I;  1Q9B A;  1RFH A;  2CWH A;  3R5A A;  7WGA A;  3TOA A;  2CWF A;  2L7X A;  2QQC A;  1CT0 I;  3RU0 A;  1UVG A;  1PTR A;  1CGJ I;  2SGF I;  1N13 A;  2B0U C;  5FUV A;  1MJA A;  1TGS I;  1OVO A;  1WTJ A;  2ROW A;  1Y8F A;  2E5R A;  4WP4 A;  1IW4 A;  1FAQ A;  3OVO A;  1TUS A;  5HI7 A;  1LR7 A;  1DS2 I;  2E73 A;  5FUX A;  5JHW C;  1Z2I A;  1Z7K B;  5J8C A;  1K7U A;  2QPO A;  2NU0 I;  9WGA A;  2W0T A;  1OMU A;  1Y1B A;  5E3Q A;  5J8F A;  2NU3 I;  1SGD I;  2GKV A;  3GOX A;  1FAR A;  1UVF A;  2GKR I;  1H0Z A;  3UEY A;  4UXJ A;  1SGQ I;  2ARP F;  4HGU A;  1MJB A;  4JCV E;  1FY7 A;  2WCY A;  4E1R A;  1HJA I;  2DB6 A;  2UZ3 A;  1CHO I;  1OMT A;  1XX6 A;  2KMO A;  3FSX A;  1WGC A;  2A20 A;  1TBQ R;  5EX0 A;  2WVJ A;  3UGI A;  4SGB I;  3R5C A;  2ERW A;  1V1H A;  2YUU A;  5E3R A;  3TOB A;  1PPF I;  2X3T A;  3TJQ A;  2RIJ A;  2K9H A;  1TIH A;  5EX3 A;  1X74 A;  2PQ8 A;  3OXF A;  1TBN A;  4A24 A;  1TUR A;  2LB7 A;  2V1C C;  3QTL D;  4GI3 C;  3OXG A;  2KCX A;  1SGR I;  2WGC A;  2YQP A;  1XBT A;  1M8C A;  2ENZ A;  2KMR A;  1W3S A;  2N71 A;  2SGQ I;  2OZU A;  3R5D A;  1HPT A; 
#chains in the Genus database with same CATH homology
 2NU4 I;  4L9M A;  3B4V C;  1XA6 A;  2OD1 A;  3D00 A;  2V53 A;  5DAE A;  3UFF A;  3FC3 A;  2JA1 A;  2SGD I;  3UEJ A;  2LEO A;  3E2I A;  1VDD A;  2QQD A;  3OL0 A;  1X4S A;  2XRC A;  1M8B A;  1W4R A;  4E1P A;  1BMO A;  2N1A B;  5HQ8 A;  2BUS A;  1BUS A;  3KY9 A;  2V1C A;  1IY5 A;  2VRW B;  1TBO A;  1AN1 I;  2ORW A;  1SGP I;  4UXH A;  1SGE I;  4UXI A;  2L8E A;  2B8T A;  1YTP A;  2ODD A;  2NU1 I;  3CXL A;  2N17 A;  2JW6 A;  2SGP I;  2JZM A;  3BJI A;  1SGN I;  1LR9 A;  2OVO A;  2QQE A;  1Y1C A;  1KBE A;  1PJU A;  2F3C I;  1TOT A;  2GVI A;  3VE5 A;  1LR8 A;  1KBF A;  2SGE I;  3E59 A;  5FUW A;  2J87 A;  1R0R I;  3VDU A;  1R79 A;  3QWP A;  1FYB A;  1V1I A;  2DIP A;  2QQ0 A;  2ELI A;  2CJS C;  1NUB A;  2J9R A;  2M5X A;  3OXL A;  2KMP A;  3SGB I;  5FUY A;  2NU2 I;  1CGI I;  5CCM A;  1CSO I;  1DS3 I;  1UUC A;  1CT2 I;  1SGY I;  3PDN A;  2ENN A;  3SEK C;  1CE3 A;  2JYY A;  1U5K A;  1MT1 A;  4FKD A;  3UGL A;  1IY6 A;  1OYV I;  3HH2 C;  3MEK A;  4OVO A;  2KMQ A;  4B6D A;  2ORV A;  3UGD A;  2FNF X;  1KMA A;  3SGQ I;  1PTQ A;  1PCE A;  2N52 A;  3VDP A;  2LUY A;  5CCL A;  1TBR R;  1HDL A;  2P6A C;  2GKT I;  2JXD A;  1YU6 C;  1CT4 I;  1RFH A;  2L7X A;  2QQC A;  1CT0 I;  3RU0 A;  1UVG A;  1PTR A;  1CGJ I;  2SGF I;  1N13 A;  2B0U C;  5FUV A;  1TGS I;  1OVO A;  2ROW A;  1IW4 A;  1Y8F A;  2E5R A;  1FAQ A;  3OVO A;  1TUS A;  5HI7 A;  1LR7 A;  1DS2 I;  2E73 A;  5FUX A;  5JHW C;  1Z7K B;  2QPO A;  2NU0 I;  2W0T A;  1OMU A;  1Y1B A;  2NU3 I;  1SGD I;  2GKV A;  3GOX A;  1FAR A;  1UVF A;  2GKR I;  1H0Z A;  3UEY A;  4UXJ A;  1SGQ I;  2ARP F;  4HGU A;  4JCV E;  2WCY A;  4E1R A;  1HJA I;  2DB6 A;  2UZ3 A;  1CHO I;  1OMT A;  1XX6 A;  2KMO A;  5EX0 A;  2A20 A;  1TBQ R;  2WVJ A;  3UGI A;  4SGB I;  2ERW A;  1V1H A;  2YUU A;  1PPF I;  3TJQ A;  2K9H A;  1TIH A;  5EX3 A;  1X74 A;  3OXF A;  1TBN A;  4A24 A;  1TUR A;  2V1C C;  3QTL D;  4GI3 C;  3OXG A;  2KCX A;  1SGR I;  2YQP A;  1XBT A;  1M8C A;  2ENZ A;  2KMR A;  1W3S A;  2N71 A;  2SGQ I;  1HPT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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