4B6DA

Structure of the atypical c1 domain of mgcracgap
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
60
structure length
60
Chain Sequence
GPLGSMRLHDFVSKTVIKPESCVPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Signaling protein
source organism Homo sapiens
publication title Centralspindlin Links the Mitotic Spindle to the Plasma Membrane During Cytokinesis.
pubmed doi rcsb
molecule keywords RAC GTPASE-ACTIVATING PROTEIN 1
total genus 10
structure length 60
sequence length 60
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2012-08-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00130 C1_1 Phorbol esters/diacylglycerol binding domain (C1 domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.20 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 4b6dA00
1KBEA 1XBTA 2JA1A 2FNFX 2ORVA 1XA6A 2ENNA 4UXHA 2QQEA 3UEYA 4FKDA 5FUVA 4L9MA 1PTQA 5FUWA 2ELIA 3BJIA 4UXIA 2YUUA 2WVJA 3CXLA 3UGIA 1PTRA 3UEJA 1W4RA 2QPOA 2UZ3A 1TBNA 3UFFA 4B6DA 3E2IA 1XX6A 3KY9A 2E73A 2J87A 3UGDA 1KBFA 2ORWA 1RFHA 2QQ0A 2GVIA 2ROWA 5FUXA 1FAQA 3UGLA 2ENZA 2B8TA 1R79A 4UXJA 5FUYA 1Y8FA 1FARA 2DB6A 2VRWB 1TBOA 2J9RA
chains in the Genus database with same CATH superfamily
3VDPA 1KMAA 4MPIA 2FNFX 2CWHA 1XA6A 2ENNA 2ORVA 3UEYA 1CT4I 1DS2I 1UVGA 2SGQI 1TIHA 5EX3A 3TOAA 1V1IA 3TO9A 1IY5A 1SGRI 2OVOA 1CT2I 2E5RA 1K7VA 4B6DA 3E2IA 3KY9A 2ROWA 2GVIA 1WGTA 1BUSA 3TO7A 4DNCA 1TBQR 1M8BA 1W3SA 1HDLA 1K7UA 2SGEI 2W0TA 3SGBI 2B8TA 2X52A 1R79A 1VDDA 3E59A 5EX0A 2CWGA 5JHWC 1CE3A 1FARA 5CCMA 1CSOI 3R5CA 2V53A 1TURA 3R5DA 2NU4I 3FSYA 2V1CA 1KBEA 1TOTA 2JW6A 2DKVA 4E1PA 1CGJI 2SGPI 1WKXA 2K9HA 1V1HA 2QQEA 4FKDA 5DAEA 1UHAA 2RIJA 2YUUA 3OXFA 3GOXA 1M8CA 2GKVA 1HEVA 3UEJA 1AN1I 2KMQA 1HJAI 1LR9A 2ODDA 2OD1A 1MT1A 4WP4A 1W4RA 2QPOA 3SEKC 2XRCA 1CHOI 1IY6A 4OVOA 1SGEI 2KMRA 3OXGA 2RC4A 3UGDA 2J87A 1KBFA 2BUSA 2CWFA 3RU0A 5HI7A 5FUXA 1OVOA 2JYYA 2SGDI 2N52A 2NU3I 1SGNI 1H0ZA 1OYVI 1SGYI 1Y1CA 3QAHA 4UXJA 2NU2I 1P9GA 5FUYA 1NUBA 1TUSA 1OMTA 2JZMA 4SGBI 3UOEA 1Y8FA 3FC3A 2ARPF 1Q9BA 2VRWB 1TBOA 2SGFI 3TJQA 2J9RA 3PDNA 2WCYA 1TBRR 4E1RA 1S20A 1U5KA 1XBTA 2DIPA 3MEKA 3QWPA 4UXHA 3TOBA 5FUWA 5E3PA 1OMUA 1PTQA 2ELIA 3BJIA 1Y1BA 1K7TA 2N1AB 3CXLA 2GKTI 2JXDA 2KMPA 4UXIA 9WGAA 1PTRA 1UUCA 1NXUA 4GI3C 1MJAA 3VE5A 5J8CA 1SGPI 2UZ3A 2CJSC 3OL0A 2OU2A 1XX6A 3HH2C 1BMOA 2E73A 2NU1I 4JCVE 3R5BA 2YQPA 1FYBA 2KMOA 1WTJA 3TO6A 1PPFI 2N17A 3UGLA 4AMLA 2UVOA 2ENZA 4A24A 1SGQI 2F3CI 2LUYA 2M5XA 2OZUA 1ULNA 1ULKA 3D00A 1HPTA 7WGAA 1X4SA 1YU6C 2PQ8A 2WGCA 2JA1A 1X74A 2L8EA 1DS3I 1CT0I 2L7XA 1MJ9A 2P6AC 5FUVA 4L9MA 1TGSI 2WVJA 1Z7KB 1PJUA 2GKRI 2KCXA 1WGCA 1MJBA 3R5AA 2QQCA 5E3RA 1SGDI 5J8FA 3OVOA 4HGUA 1R0RI 1TBNA 3UFFA 3UGIA 5CCLA 1PCEA 3VDUA 1YTPA 1Z2IA 1RFHA 2ORWA 2QQ0A 1CGII 2LB7A 2B0UC 1LR8A 3B4VC 3QTLD 5E3QA 1IW4A 3FSXA 1LR7A 1FAQA 1ULMA 2V1CC 2LEOA 5HQ8A 2N71A 1FY7A 3OXLA 1N13A 1UVFA 2X3TA 3SGQI 2NU0I 2A20A 2Y0MA 2DB6A 2ERWA 2QQDA 2GIVA 1P9ZA
chains in the Genus database with same CATH topology
3VDPA 1KMAA 2FNFX 2ORVA 1XA6A 2ENNA 3UEYA 1CT4I 1DS2I 1UVGA 2SGQI 1TIHA 5EX3A 1V1IA 1IY5A 1SGRI 2OVOA 1CT2I 2E5RA 4B6DA 3E2IA 3KY9A 2ROWA 2GVIA 1BUSA 1TBQR 1M8BA 1W3SA 1HDLA 2SGEI 2W0TA 3SGBI 2B8TA 1R79A 1VDDA 3E59A 5EX0A 1CE3A 5JHWC 1FARA 5CCMA 1CSOI 2V53A 1TURA 2NU4I 2V1CA 1KBEA 1TOTA 2JW6A 4E1PA 1CGJI 2SGPI 2K9HA 2QQEA 1V1HA 4FKDA 5DAEA 2YUUA 3GOXA 1M8CA 2GKVA 3UEJA 1AN1I 2KMQA 1HJAI 1LR9A 2ODDA 2OD1A 1MT1A 1W4RA 2QPOA 3SEKC 2XRCA 1CHOI 1IY6A 4OVOA 1SGEI 2KMRA 3OXGA 3UGDA 2J87A 1KBFA 2BUSA 3RU0A 5HI7A 5FUXA 1OVOA 2JYYA 2SGDI 2N52A 2NU3I 1SGNI 1H0ZA 1OYVI 1SGYI 1Y1CA 4UXJA 2NU2I 5FUYA 1NUBA 1TUSA 1OMTA 2JZMA 4SGBI 1Y8FA 3FC3A 2ARPF 2VRWB 1TBOA 2SGFI 3TJQA 2J9RA 3PDNA 2WCYA 1TBRR 4E1RA 1U5KA 1XBTA 2DIPA 3MEKA 3QWPA 4UXHA 5FUWA 3UGIA 1OMUA 1PTQA 2ELIA 3BJIA 1Y1BA 3OXFA 2N1AB 3CXLA 2GKTI 2JXDA 2KMPA 4UXIA 1PTRA 1UUCA 4GI3C 3VE5A 1SGPI 2UZ3A 2CJSC 3OL0A 1XX6A 3HH2C 1BMOA 2E73A 2NU1I 4JCVE 1FYBA 2YQPA 2KMOA 1PPFI 2N17A 3UGLA 2ENZA 4A24A 1SGQI 2F3CI 2LUYA 2M5XA 3D00A 1HPTA 1YU6C 1X4SA 2JA1A 1X74A 2L8EA 1DS3I 1CT0I 2L7XA 2P6AC 5FUVA 4L9MA 1TGSI 2WVJA 1Z7KB 1PJUA 2GKRI 2KCXA 2QQCA 1SGDI 3OVOA 4HGUA 1R0RI 1TBNA 3UFFA 5CCLA 1PCEA 3VDUA 1YTPA 2ORWA 1RFHA 2QQ0A 1CGII 3B4VC 2B0UC 1LR8A 3QTLD 1IW4A 1FAQA 1LR7A 2V1CC 2LEOA 5HQ8A 2N71A 3OXLA 1N13A 1UVFA 3SGQI 2NU0I 2A20A 2DB6A 2ERWA 2QQDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KBE A;  1XBT A;  2JA1 A;  2FNF X;  2ORV A;  1XA6 A;  2ENN A;  4UXH A;  2QQE A;  3UEY A;  4FKD A;  5FUV A;  4L9M A;  1PTQ A;  5FUW A;  2ELI A;  3BJI A;  4UXI A;  2YUU A;  2WVJ A;  3CXL A;  3UGI A;  1PTR A;  3UEJ A;  1W4R A;  2QPO A;  2UZ3 A;  1TBN A;  3UFF A;  4B6D A;  3E2I A;  1XX6 A;  3KY9 A;  2E73 A;  2J87 A;  3UGD A;  1KBF A;  2ORW A;  1RFH A;  2QQ0 A;  2GVI A;  2ROW A;  5FUX A;  1FAQ A;  3UGL A;  2ENZ A;  2B8T A;  1R79 A;  4UXJ A;  5FUY A;  1Y8F A;  1FAR A;  2DB6 A;  2VRW B;  1TBO A;  2J9R A; 
#chains in the Genus database with same CATH topology
 3VDP A;  1KMA A;  4MPI A;  2FNF X;  2CWH A;  1XA6 A;  2ENN A;  2ORV A;  3UEY A;  1CT4 I;  1DS2 I;  1UVG A;  2SGQ I;  1TIH A;  5EX3 A;  3TOA A;  1V1I A;  3TO9 A;  1IY5 A;  1SGR I;  2OVO A;  1CT2 I;  2E5R A;  1K7V A;  4B6D A;  3E2I A;  3KY9 A;  2ROW A;  2GVI A;  1WGT A;  1BUS A;  3TO7 A;  4DNC A;  1TBQ R;  1M8B A;  1W3S A;  1HDL A;  1K7U A;  2SGE I;  2W0T A;  3SGB I;  2B8T A;  2X52 A;  1R79 A;  1VDD A;  3E59 A;  5EX0 A;  2CWG A;  5JHW C;  1CE3 A;  1FAR A;  5CCM A;  1CSO I;  3R5C A;  2V53 A;  1TUR A;  3R5D A;  2NU4 I;  3FSY A;  2V1C A;  1KBE A;  1TOT A;  2JW6 A;  2DKV A;  4E1P A;  1CGJ I;  2SGP I;  1WKX A;  2K9H A;  1V1H A;  2QQE A;  4FKD A;  5DAE A;  1UHA A;  2RIJ A;  2YUU A;  3OXF A;  3GOX A;  1M8C A;  2GKV A;  1HEV A;  3UEJ A;  1AN1 I;  2KMQ A;  1HJA I;  1LR9 A;  2ODD A;  2OD1 A;  1MT1 A;  4WP4 A;  1W4R A;  2QPO A;  3SEK C;  2XRC A;  1CHO I;  1IY6 A;  4OVO A;  1SGE I;  2KMR A;  3OXG A;  2RC4 A;  3UGD A;  2J87 A;  1KBF A;  2BUS A;  2CWF A;  3RU0 A;  5HI7 A;  5FUX A;  1OVO A;  2JYY A;  2SGD I;  2N52 A;  2NU3 I;  1SGN I;  1H0Z A;  1OYV I;  1SGY I;  1Y1C A;  3QAH A;  4UXJ A;  2NU2 I;  1P9G A;  5FUY A;  1NUB A;  1TUS A;  1OMT A;  2JZM A;  4SGB I;  3UOE A;  1Y8F A;  3FC3 A;  2ARP F;  1Q9B A;  2VRW B;  1TBO A;  2SGF I;  3TJQ A;  2J9R A;  3PDN A;  2WCY A;  1TBR R;  4E1R A;  1S20 A;  1U5K A;  1XBT A;  2DIP A;  3MEK A;  3QWP A;  4UXH A;  3TOB A;  5FUW A;  5E3P A;  1OMU A;  1PTQ A;  2ELI A;  3BJI A;  1Y1B A;  1K7T A;  2N1A B;  3CXL A;  2GKT I;  2JXD A;  2KMP A;  4UXI A;  9WGA A;  1PTR A;  1UUC A;  1NXU A;  4GI3 C;  1MJA A;  3VE5 A;  5J8C A;  1SGP I;  2UZ3 A;  2CJS C;  3OL0 A;  2OU2 A;  1XX6 A;  3HH2 C;  1BMO A;  2E73 A;  2NU1 I;  4JCV E;  3R5B A;  2YQP A;  1FYB A;  2KMO A;  1WTJ A;  3TO6 A;  1PPF I;  2N17 A;  3UGL A;  4AML A;  2UVO A;  2ENZ A;  4A24 A;  1SGQ I;  2F3C I;  2LUY A;  2M5X A;  2OZU A;  1ULN A;  1ULK A;  3D00 A;  1HPT A;  7WGA A;  1X4S A;  1YU6 C;  2PQ8 A;  2WGC A;  2JA1 A;  1X74 A;  2L8E A;  1DS3 I;  1CT0 I;  2L7X A;  1MJ9 A;  2P6A C;  5FUV A;  4L9M A;  1TGS I;  2WVJ A;  1Z7K B;  1PJU A;  2GKR I;  2KCX A;  1WGC A;  1MJB A;  3R5A A;  2QQC A;  5E3R A;  1SGD I;  5J8F A;  3OVO A;  4HGU A;  1R0R I;  1TBN A;  3UFF A;  3UGI A;  5CCL A;  1PCE A;  3VDU A;  1YTP A;  1Z2I A;  1RFH A;  2ORW A;  2QQ0 A;  1CGI I;  2LB7 A;  2B0U C;  1LR8 A;  3B4V C;  3QTL D;  5E3Q A;  1IW4 A;  3FSX A;  1LR7 A;  1FAQ A;  1ULM A;  2V1C C;  2LEO A;  5HQ8 A;  2N71 A;  1FY7 A;  3OXL A;  1N13 A;  1UVF A;  2X3T A;  3SGQ I;  2NU0 I;  2A20 A;  2Y0M A;  2DB6 A;  2ERW A;  2QQD A;  2GIV A;  1P9Z A; 
#chains in the Genus database with same CATH homology
 3VDP A;  1KMA A;  2FNF X;  2ORV A;  1XA6 A;  2ENN A;  3UEY A;  1CT4 I;  1DS2 I;  1UVG A;  2SGQ I;  1TIH A;  5EX3 A;  1V1I A;  1IY5 A;  1SGR I;  2OVO A;  1CT2 I;  2E5R A;  4B6D A;  3E2I A;  3KY9 A;  2ROW A;  2GVI A;  1BUS A;  1TBQ R;  1M8B A;  1W3S A;  1HDL A;  2SGE I;  2W0T A;  3SGB I;  2B8T A;  1R79 A;  1VDD A;  3E59 A;  5EX0 A;  1CE3 A;  5JHW C;  1FAR A;  5CCM A;  1CSO I;  2V53 A;  1TUR A;  2NU4 I;  2V1C A;  1KBE A;  1TOT A;  2JW6 A;  4E1P A;  1CGJ I;  2SGP I;  2K9H A;  2QQE A;  1V1H A;  4FKD A;  5DAE A;  2YUU A;  3GOX A;  1M8C A;  2GKV A;  3UEJ A;  1AN1 I;  2KMQ A;  1HJA I;  1LR9 A;  2ODD A;  2OD1 A;  1MT1 A;  1W4R A;  2QPO A;  3SEK C;  2XRC A;  1CHO I;  1IY6 A;  4OVO A;  1SGE I;  2KMR A;  3OXG A;  3UGD A;  2J87 A;  1KBF A;  2BUS A;  3RU0 A;  5HI7 A;  5FUX A;  1OVO A;  2JYY A;  2SGD I;  2N52 A;  2NU3 I;  1SGN I;  1H0Z A;  1OYV I;  1SGY I;  1Y1C A;  4UXJ A;  2NU2 I;  5FUY A;  1NUB A;  1TUS A;  1OMT A;  2JZM A;  4SGB I;  1Y8F A;  3FC3 A;  2ARP F;  2VRW B;  1TBO A;  2SGF I;  3TJQ A;  2J9R A;  3PDN A;  2WCY A;  1TBR R;  4E1R A;  1U5K A;  1XBT A;  2DIP A;  3MEK A;  3QWP A;  4UXH A;  5FUW A;  3UGI A;  1OMU A;  1PTQ A;  2ELI A;  3BJI A;  1Y1B A;  3OXF A;  2N1A B;  3CXL A;  2GKT I;  2JXD A;  2KMP A;  4UXI A;  1PTR A;  1UUC A;  4GI3 C;  3VE5 A;  1SGP I;  2UZ3 A;  2CJS C;  3OL0 A;  1XX6 A;  3HH2 C;  1BMO A;  2E73 A;  2NU1 I;  4JCV E;  1FYB A;  2YQP A;  2KMO A;  1PPF I;  2N17 A;  3UGL A;  2ENZ A;  4A24 A;  1SGQ I;  2F3C I;  2LUY A;  2M5X A;  3D00 A;  1HPT A;  1YU6 C;  1X4S A;  2JA1 A;  1X74 A;  2L8E A;  1DS3 I;  1CT0 I;  2L7X A;  2P6A C;  5FUV A;  4L9M A;  1TGS I;  2WVJ A;  1Z7K B;  1PJU A;  2GKR I;  2KCX A;  2QQC A;  1SGD I;  3OVO A;  4HGU A;  1R0R I;  1TBN A;  3UFF A;  5CCL A;  1PCE A;  3VDU A;  1YTP A;  2ORW A;  1RFH A;  2QQ0 A;  1CGI I;  3B4V C;  2B0U C;  1LR8 A;  3QTL D;  1IW4 A;  1FAQ A;  1LR7 A;  2V1C C;  2LEO A;  5HQ8 A;  2N71 A;  3OXL A;  1N13 A;  1UVF A;  3SGQ I;  2NU0 I;  2A20 A;  2DB6 A;  2ERW A;  2QQD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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