4B6DA

Structure of the atypical c1 domain of mgcracgap
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
60
structure length
60
Chain Sequence
GPLGSMRLHDFVSKTVIKPESCVPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Centralspindlin Links the Mitotic Spindle to the Plasma Membrane During Cytokinesis.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords RAC GTPASE-ACTIVATING PROTEIN 1
total genus 10
structure length 60
sequence length 60
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2012-08-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00130 C1_1 Phorbol esters/diacylglycerol binding domain (C1 domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.20 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 4b6dA00
1R79A 5FUVA 3UGIA 2B8TA 2ENNA 2J9RA 2ROWA 4L9MA 2DB6A 3BJIA 1XA6A 1KBEA 2ORVA 2ENZA 3KY9A 4UXHA 1RFHA 1FAQA 2ELIA 4UXJA 5FUYA 1Y8FA 3UEYA 1FARA 2ORWA 2FNFX 1PTQA 4FKDA 3E2IA 3UGDA 2QQ0A 2QQEA 1XX6A 1KBFA 1PTRA 2J87A 3UEJA 1XBTA 3UFFA 2GVIA 2UZ3A 5FUWA 2VRWB 3CXLA 2YUUA 4UXIA 2WVJA 1TBOA 1TBNA 1W4RA 2JA1A 2E73A 3UGLA 5FUXA 2QPOA 4B6DA
chains in the Genus database with same CATH superfamily
2JXDA 1IY6A 1CT4I 1SGYI 2X3TA 2LB7A 3OXLA 4A24A 2ARPF 2LUYA 4L9MA 1IW4A 1UVFA 2WGCA 2NU0I 4DNCA 4UXHA 3OXGA 2ELIA 3R5AA 4UXJA 2SGQI 2CWFA 2W0TA 2GIVA 3OVOA 1X4SA 7WGAA 1Q9BA 2F3CI 1FARA 2JZMA 1TUSA 1H0ZA 1P9GA 2DIPA 2LEOA 2Y0MA 1PTQA 1TBQR 2KMOA 2KMQA 2SGEI 1PTRA 1SGPI 1TURA 2XRCA 3UEJA 2V1CA 1NUBA 1WGTA 1KBFA 1CGII 1HJAI 2N17A 2ERWA 3TOBA 2VRWB 1YU6C 2SGFI 3VDPA 2WVJA 2NU4I 2V1CC 4AMLA 2JA1A 1OMUA 5E3QA 4B6DA 5CCLA 1KMAA 1LR9A 5FUVA 4JCVE 2B8TA 1ULNA 1WGCA 2NU1I 2J9RA 2ROWA 1BMOA 1FY7A 3VDUA 5E3PA 1XA6A 1KBEA 1CSOI 1SGQI 2ENZA 3KY9A 3R5DA 5EX3A 4SGBI 3SGQI 1MT1A 1TGSI 1LR7A 1CE3A 1SGRI 1X74A 4E1RA 5FUYA 3R5CA 1K7TA 1Y8FA 2CJSC 2KMRA 3TOAA 2GKVA 3UEYA 2N1AB 1HDLA 2KCXA 5J8FA 1DS2I 2B0UC 1PJUA 2KMPA 2E5RA 2JYYA 2QQEA 1LR8A 1SGDI 3D00A 3RU0A 2J87A 1XBTA 2GVIA 1MJAA 1UVGA 2YUUA 1TIHA 2SGDI 1M8CA 3CXLA 3PDNA 1CGJI 1TBNA 1W4RA 5CCMA 1VDDA 4FKDA 1MJBA 1Y1BA 2CWHA 2OU2A 4MPIA 3TO9A 3UGLA 1S20A 1R79A 5E3RA 2ENNA 1W3SA 2JW6A 2GKTI 2SGPI 2ORVA 5EX0A 5DAEA 3VE5A 1U5KA 1V1HA 1ULMA 1IY5A 1HPTA 1TOTA 4OVOA 1Y1CA 2M5XA 1TBRR 3UOEA 1OMTA 1ULKA 1Z7KB 1OVOA 2OVOA 2N52A 2QQDA 2NU2I 3OXFA 4GI3C 3SGBI 1K7VA 1PPFI 3OL0A 3E2IA 1K7UA 4UXIA 2CWGA 3UGDA 9WGAA 2RC4A 1YTPA 2A20A 2UZ3A 5HI7A 1CT2I 1R0RI 1UUCA 2BUSA 3E59A 4E1PA 2V53A 1FYBA 2N71A 2OD1A 3UFFA 3FC3A 2QPOA 2P6AC 3QWPA 1BUSA 1PCEA 2YQPA 3SEKC 3TO6A 2RIJA 2OZUA 3UGIA 1OYVI 1CT0I 1P9ZA 2DKVA 1CHOI 2DB6A 3BJIA 2K9HA 2WCYA 5J8CA 1RFHA 1SGEI 2L7XA 3TJQA 1FAQA 2L8EA 2ODDA 3MEKA 3B4VC 3QAHA 2UVOA 5JHWC 1HEVA 3QTLD 5HQ8A 1N13A 1AN1I 2QQCA 2ORWA 2FNFX 2X52A 1SGNI 3FSXA 2PQ8A 1UHAA 2QQ0A 2NU3I 1XX6A 1NXUA 2GKRI 5FUWA 3TO7A 1WTJA 4WP4A 1V1IA 1WKXA 1Z2IA 1DS3I 1TBOA 1MJ9A 3FSYA 3R5BA 2E73A 3HH2C 4HGUA 3GOXA 1M8BA 5FUXA
chains in the Genus database with same CATH topology
2JXDA 1IY6A 1CT4I 1SGYI 3OXLA 4A24A 2ARPF 2LUYA 4L9MA 1UVFA 2NU0I 4UXHA 3OXGA 2ELIA 4UXJA 2SGQI 2W0TA 3OVOA 1X4SA 2F3CI 1FARA 2JZMA 1TUSA 1H0ZA 2DIPA 2LEOA 1PTQA 1TBQR 2KMOA 2KMQA 2SGEI 1PTRA 1SGPI 1TURA 2XRCA 3UEJA 2V1CA 1NUBA 1KBFA 1CGII 1HJAI 2N17A 2ERWA 2VRWB 1YU6C 2SGFI 3VDPA 2WVJA 2NU4I 2V1CC 2JA1A 1OMUA 4B6DA 5CCLA 1KMAA 1LR9A 5FUVA 4JCVE 2B8TA 2NU1I 2J9RA 2ROWA 1BMOA 3VDUA 1XA6A 1KBEA 1CSOI 1SGQI 2ENZA 3KY9A 5EX3A 1CE3A 4SGBI 3SGQI 1MT1A 1TGSI 1LR7A 1SGRI 1X74A 4E1RA 5FUYA 2CJSC 1Y8FA 2KMRA 2GKVA 3UEYA 2N1AB 1HDLA 2KCXA 1DS2I 2B0UC 1PJUA 2KMPA 2E5RA 2JYYA 2QQEA 1LR8A 1SGDI 3D00A 3RU0A 2J87A 1XBTA 2GVIA 1UVGA 2YUUA 1TIHA 2SGDI 1M8CA 3CXLA 3PDNA 1CGJI 1TBNA 1W4RA 5CCMA 1VDDA 4FKDA 1IW4A 1Y1BA 3UGLA 1R79A 2ENNA 1W3SA 2JW6A 2GKTI 2SGPI 2ORVA 5EX0A 5DAEA 3VE5A 1U5KA 1V1HA 1IY5A 1HPTA 1TOTA 4OVOA 1Y1CA 2M5XA 1TBRR 1OMTA 1Z7KB 2OVOA 1OVOA 3OXFA 2N52A 2QQDA 2NU2I 4GI3C 3SGBI 1PPFI 3OL0A 3E2IA 3UGDA 1YTPA 2A20A 2UZ3A 5HI7A 1CT2I 1R0RI 1UUCA 2BUSA 3E59A 4E1PA 2V53A 1FYBA 2N71A 2OD1A 3UFFA 3FC3A 2QPOA 2P6AC 3QWPA 1BUSA 1PCEA 2YQPA 3SEKC 3UGIA 1OYVI 1CT0I 1CHOI 2DB6A 3BJIA 2K9HA 2WCYA 1RFHA 1SGEI 2L7XA 3TJQA 1FAQA 2L8EA 2ODDA 3MEKA 3B4VC 5JHWC 3QTLD 5HQ8A 1N13A 1AN1I 2QQCA 2ORWA 2FNFX 1SGNI 2QQ0A 2NU3I 1XX6A 2GKRI 5FUWA 1V1IA 4UXIA 4HGUA 1DS3I 1TBOA 3GOXA 2E73A 3HH2C 1M8BA 5FUXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R79 A;  5FUV A;  3UGI A;  2B8T A;  2ENN A;  2J9R A;  2ROW A;  4L9M A;  2DB6 A;  3BJI A;  1XA6 A;  1KBE A;  2ORV A;  2ENZ A;  3KY9 A;  4UXH A;  1RFH A;  1FAQ A;  2ELI A;  4UXJ A;  5FUY A;  1Y8F A;  3UEY A;  1FAR A;  2ORW A;  2FNF X;  1PTQ A;  4FKD A;  3E2I A;  3UGD A;  2QQ0 A;  2QQE A;  1XX6 A;  1KBF A;  1PTR A;  2J87 A;  3UEJ A;  1XBT A;  3UFF A;  2GVI A;  2UZ3 A;  5FUW A;  2VRW B;  3CXL A;  2YUU A;  4UXI A;  2WVJ A;  1TBO A;  1TBN A;  1W4R A;  2JA1 A;  2E73 A;  3UGL A;  5FUX A;  2QPO A;  4B6D A; 
#chains in the Genus database with same CATH topology
 2JXD A;  1IY6 A;  1CT4 I;  1SGY I;  2X3T A;  2LB7 A;  3OXL A;  4A24 A;  2ARP F;  2LUY A;  4L9M A;  1IW4 A;  1UVF A;  2WGC A;  2NU0 I;  4DNC A;  4UXH A;  3OXG A;  2ELI A;  3R5A A;  4UXJ A;  2SGQ I;  2CWF A;  2W0T A;  2GIV A;  3OVO A;  1X4S A;  7WGA A;  1Q9B A;  2F3C I;  1FAR A;  2JZM A;  1TUS A;  1H0Z A;  1P9G A;  2DIP A;  2LEO A;  2Y0M A;  1PTQ A;  1TBQ R;  2KMO A;  2KMQ A;  2SGE I;  1PTR A;  1SGP I;  1TUR A;  2XRC A;  3UEJ A;  2V1C A;  1NUB A;  1WGT A;  1KBF A;  1CGI I;  1HJA I;  2N17 A;  2ERW A;  3TOB A;  2VRW B;  1YU6 C;  2SGF I;  3VDP A;  2WVJ A;  2NU4 I;  2V1C C;  4AML A;  2JA1 A;  1OMU A;  5E3Q A;  4B6D A;  5CCL A;  1KMA A;  1LR9 A;  5FUV A;  4JCV E;  2B8T A;  1ULN A;  1WGC A;  2NU1 I;  2J9R A;  2ROW A;  1BMO A;  1FY7 A;  3VDU A;  5E3P A;  1XA6 A;  1KBE A;  1CSO I;  1SGQ I;  2ENZ A;  3KY9 A;  3R5D A;  5EX3 A;  4SGB I;  3SGQ I;  1MT1 A;  1TGS I;  1LR7 A;  1CE3 A;  1SGR I;  1X74 A;  4E1R A;  5FUY A;  3R5C A;  1K7T A;  1Y8F A;  2CJS C;  2KMR A;  3TOA A;  2GKV A;  3UEY A;  2N1A B;  1HDL A;  2KCX A;  5J8F A;  1DS2 I;  2B0U C;  1PJU A;  2KMP A;  2E5R A;  2JYY A;  2QQE A;  1LR8 A;  1SGD I;  3D00 A;  3RU0 A;  2J87 A;  1XBT A;  2GVI A;  1MJA A;  1UVG A;  2YUU A;  1TIH A;  2SGD I;  1M8C A;  3CXL A;  3PDN A;  1CGJ I;  1TBN A;  1W4R A;  5CCM A;  1VDD A;  4FKD A;  1MJB A;  1Y1B A;  2CWH A;  2OU2 A;  4MPI A;  3TO9 A;  3UGL A;  1S20 A;  1R79 A;  5E3R A;  2ENN A;  1W3S A;  2JW6 A;  2GKT I;  2SGP I;  2ORV A;  5EX0 A;  5DAE A;  3VE5 A;  1U5K A;  1V1H A;  1ULM A;  1IY5 A;  1HPT A;  1TOT A;  4OVO A;  1Y1C A;  2M5X A;  1TBR R;  3UOE A;  1OMT A;  1ULK A;  1Z7K B;  1OVO A;  2OVO A;  2N52 A;  2QQD A;  2NU2 I;  3OXF A;  4GI3 C;  3SGB I;  1K7V A;  1PPF I;  3OL0 A;  3E2I A;  1K7U A;  4UXI A;  2CWG A;  3UGD A;  9WGA A;  2RC4 A;  1YTP A;  2A20 A;  2UZ3 A;  5HI7 A;  1CT2 I;  1R0R I;  1UUC A;  2BUS A;  3E59 A;  4E1P A;  2V53 A;  1FYB A;  2N71 A;  2OD1 A;  3UFF A;  3FC3 A;  2QPO A;  2P6A C;  3QWP A;  1BUS A;  1PCE A;  2YQP A;  3SEK C;  3TO6 A;  2RIJ A;  2OZU A;  3UGI A;  1OYV I;  1CT0 I;  1P9Z A;  2DKV A;  1CHO I;  2DB6 A;  3BJI A;  2K9H A;  2WCY A;  5J8C A;  1RFH A;  1SGE I;  2L7X A;  3TJQ A;  1FAQ A;  2L8E A;  2ODD A;  3MEK A;  3B4V C;  3QAH A;  2UVO A;  5JHW C;  1HEV A;  3QTL D;  5HQ8 A;  1N13 A;  1AN1 I;  2QQC A;  2ORW A;  2FNF X;  2X52 A;  1SGN I;  3FSX A;  2PQ8 A;  1UHA A;  2QQ0 A;  2NU3 I;  1XX6 A;  1NXU A;  2GKR I;  5FUW A;  3TO7 A;  1WTJ A;  4WP4 A;  1V1I A;  1WKX A;  1Z2I A;  1DS3 I;  1TBO A;  1MJ9 A;  3FSY A;  3R5B A;  2E73 A;  3HH2 C;  4HGU A;  3GOX A;  1M8B A;  5FUX A; 
#chains in the Genus database with same CATH homology
 2JXD A;  1IY6 A;  1CT4 I;  1SGY I;  3OXL A;  4A24 A;  2ARP F;  2LUY A;  4L9M A;  1UVF A;  2NU0 I;  4UXH A;  3OXG A;  2ELI A;  4UXJ A;  2SGQ I;  2W0T A;  3OVO A;  1X4S A;  2F3C I;  1FAR A;  2JZM A;  1TUS A;  1H0Z A;  2DIP A;  2LEO A;  1PTQ A;  1TBQ R;  2KMO A;  2KMQ A;  2SGE I;  1PTR A;  1SGP I;  1TUR A;  2XRC A;  3UEJ A;  2V1C A;  1NUB A;  1KBF A;  1CGI I;  1HJA I;  2N17 A;  2ERW A;  2VRW B;  1YU6 C;  2SGF I;  3VDP A;  2WVJ A;  2NU4 I;  2V1C C;  2JA1 A;  1OMU A;  4B6D A;  5CCL A;  1KMA A;  1LR9 A;  5FUV A;  4JCV E;  2B8T A;  2NU1 I;  2J9R A;  2ROW A;  1BMO A;  3VDU A;  1XA6 A;  1KBE A;  1CSO I;  1SGQ I;  2ENZ A;  3KY9 A;  5EX3 A;  1CE3 A;  4SGB I;  3SGQ I;  1MT1 A;  1TGS I;  1LR7 A;  1SGR I;  1X74 A;  4E1R A;  5FUY A;  2CJS C;  1Y8F A;  2KMR A;  2GKV A;  3UEY A;  2N1A B;  1HDL A;  2KCX A;  1DS2 I;  2B0U C;  1PJU A;  2KMP A;  2E5R A;  2JYY A;  2QQE A;  1LR8 A;  1SGD I;  3D00 A;  3RU0 A;  2J87 A;  1XBT A;  2GVI A;  1UVG A;  2YUU A;  1TIH A;  2SGD I;  1M8C A;  3CXL A;  3PDN A;  1CGJ I;  1TBN A;  1W4R A;  5CCM A;  1VDD A;  4FKD A;  1IW4 A;  1Y1B A;  3UGL A;  1R79 A;  2ENN A;  1W3S A;  2JW6 A;  2GKT I;  2SGP I;  2ORV A;  5EX0 A;  5DAE A;  3VE5 A;  1U5K A;  1V1H A;  1IY5 A;  1HPT A;  1TOT A;  4OVO A;  1Y1C A;  2M5X A;  1TBR R;  1OMT A;  1Z7K B;  2OVO A;  1OVO A;  3OXF A;  2N52 A;  2QQD A;  2NU2 I;  4GI3 C;  3SGB I;  1PPF I;  3OL0 A;  3E2I A;  3UGD A;  1YTP A;  2A20 A;  2UZ3 A;  5HI7 A;  1CT2 I;  1R0R I;  1UUC A;  2BUS A;  3E59 A;  4E1P A;  2V53 A;  1FYB A;  2N71 A;  2OD1 A;  3UFF A;  3FC3 A;  2QPO A;  2P6A C;  3QWP A;  1BUS A;  1PCE A;  2YQP A;  3SEK C;  3UGI A;  1OYV I;  1CT0 I;  1CHO I;  2DB6 A;  3BJI A;  2K9H A;  2WCY A;  1RFH A;  1SGE I;  2L7X A;  3TJQ A;  1FAQ A;  2L8E A;  2ODD A;  3MEK A;  3B4V C;  5JHW C;  3QTL D;  5HQ8 A;  1N13 A;  1AN1 I;  2QQC A;  2ORW A;  2FNF X;  1SGN I;  2QQ0 A;  2NU3 I;  1XX6 A;  2GKR I;  5FUW A;  1V1I A;  4UXI A;  4HGU A;  1DS3 I;  1TBO A;  3GOX A;  2E73 A;  3HH2 C;  1M8B A;  5FUX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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