4FKDA

Identification of the activator binding residues in the second cysteine-rich regulatory domain of protein kinase c theta
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
65
structure length
65
Chain Sequence
GSRRASVGSHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRCQTKVANLCEFIVTD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of the Activator Binding Residues in the Second Cysteine-Rich Regulatory Domain of Protein Kinase C Theta.
pubmed doi rcsb
molecule tags Transferase
source organism Mus musculus
molecule keywords Protein kinase C theta type
total genus 11
structure length 65
sequence length 65
ec nomenclature ec 2.7.11.13: Protein kinase C.
pdb deposition date 2012-06-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.20 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 4fkdA01
4UXHA 2VRWB 2FNFX 3BJIA 5FUVA 1W4RA 2GVIA 4UXJA 2J9RA 5FUYA 3UGLA 3UGIA 2QQEA 2WVJA 2ENZA 1TBOA 4UXIA 3UFFA 1PTQA 1XA6A 1XX6A 5FUWA 1PTRA 4B6DA 2B8TA 1R79A 3UGDA 1XBTA 1KBFA 1RFHA 2E73A 3KY9A 3UEJA 2JA1A 1TBNA 2QPOA 3CXLA 2ORVA 3UEYA 2J87A 3E2IA 2ENNA 2ROWA 2DB6A 2ELIA 2ORWA 4L9MA 5FUXA 1FAQA 2UZ3A 1FARA 4FKDA 1Y8FA 1KBEA 2YUUA 2QQ0A
chains in the Genus database with same CATH superfamily
1LR8A 3QWPA 7WGAA 1VDDA 3SGBI 1CHOI 1TGSI 2CWFA 1LR7A 2GVIA 2SGPI 5FUYA 1MJAA 3RU0A 2LB7A 3D00A 2KCXA 1PTQA 3SEKC 1PCEA 2M5XA 1XA6A 2OD1A 2W0TA 5FUWA 1Z7KB 1M8BA 2WCYA 2GKVA 1K7UA 1UHAA 1SGDI 2JYYA 5EX0A 1KBFA 1FY7A 2NU2I 2PQ8A 2JXDA 3HH2C 1IW4A 1W3SA 1UUCA 3E2IA 2ENNA 2ROWA 2SGQI 3OXLA 5HI7A 4L9MA 3TOBA 2JW6A 3E59A 3VE5A 2UZ3A 1FARA 4FKDA 1KBEA 2YUUA 3FSYA 1KMAA 2N71A 3TJQA 1ULMA 4UXHA 1DS3I 2ODDA 1TBQR 1HJAI 1ULKA 2UVOA 3MEKA 1TBRR 2N52A 2DKVA 5FUVA 1SGQI 1HDLA 1MJ9A 1R0RI 3UGLA 1OMTA 5E3QA 2WVJA 3SGQI 2V53A 1TBOA 2YQPA 3R5AA 2GKTI 3UFFA 4AMLA 1UVGA 1XX6A 3OXFA 1TIHA 1LR9A 1CT0I 1SGRI 1PTRA 1X74A 1YTPA 1DS2I 1IY6A 1R79A 1WTJA 3UGDA 1XBTA 1K7TA 4A24A 4DNCA 1TURA 1IY5A 9WGAA 1OMUA 5JHWC 5E3RA 2ORVA 2ERWA 3UEYA 2SGDI 2J87A 3OXGA 2WGCA 1CT2I 2ORWA 1P9ZA 2OVOA 4GI3C 1P9GA 2N1AB 2ARPF 2X52A 2QQ0A 3GOXA 1SGEI 2P6AC 2VRWB 1AN1I 2FNFX 2A20A 1S20A 1X4SA 3BJIA 3R5BA 4UXJA 2V1CA 4JCVE 2E5RA 2B0UC 1CT4I 3TO9A 3UGIA 2ENZA 2DIPA 2SGEI 3QTLD 2CJSC 1N13A 2GKRI 3QAHA 1V1HA 1Y1BA 2NU1I 2Y0MA 4MPIA 2B8TA 2N17A 1U5KA 1WGCA 2NU3I 1BUSA 3R5CA 3VDUA 3TOAA 2E73A 3KY9A 3UEJA 2L8EA 2BUSA 2V1CC 2QPOA 4E1RA 1WGTA 2L7XA 1CE3A 3PDNA 3FSXA 2OZUA 3R5DA 1FYBA 4WP4A 2DB6A 2ELIA 2SGFI 1CGJI 3B4VC 2KMRA 1HEVA 1Y8FA 1SGPI 3UOEA 1OVOA 2GIVA 5J8FA 2K9HA 1V1IA 3TO7A 1NXUA 2LEOA 3OL0A 1W4RA 5E3PA 2J9RA 3FC3A 4SGBI 1WKXA 3OVOA 1CGII 1Q9BA 2JZMA 2LUYA 1HPTA 1TUSA 2CWGA 2QQCA 2QQEA 4UXIA 5CCMA 5CCLA 1M8CA 2X3TA 5DAEA 2RIJA 1MJBA 1TOTA 1K7VA 1MT1A 1YU6C 4B6DA 1SGNI 1OYVI 1UVFA 1Y1CA 1PJUA 1H0ZA 1RFHA 2KMOA 2NU4I 1Z2IA 4OVOA 1PPFI 2F3CI 2JA1A 2KMQA 1CSOI 1TBNA 2NU0I 3CXLA 4HGUA 3VDPA 4E1PA 5HQ8A 2KMPA 2OU2A 2QQDA 1FAQA 2RC4A 1NUBA 5FUXA 5EX3A 1BMOA 1ULNA 3TO6A 5J8CA 2CWHA 1SGYI 2XRCA
chains in the Genus database with same CATH topology
1LR8A 3QWPA 1VDDA 3SGBI 1CHOI 1TGSI 1LR7A 2GVIA 2SGPI 5FUYA 3RU0A 3D00A 2KCXA 1PTQA 3SEKC 1PCEA 2M5XA 1XA6A 2OD1A 2W0TA 5FUWA 1Z7KB 1M8BA 2WCYA 2GKVA 2JYYA 1SGDI 5EX0A 1KBFA 2NU2I 2JXDA 3HH2C 1IW4A 1W3SA 1UUCA 3E2IA 2ENNA 2ROWA 2SGQI 3OXLA 5HI7A 4L9MA 3VE5A 2JW6A 3E59A 2UZ3A 1FARA 4FKDA 1KBEA 2YUUA 1KMAA 2N71A 3TJQA 4UXHA 1DS3I 2ODDA 1TBQR 1HJAI 3MEKA 1TBRR 2N52A 5FUVA 1SGQI 1HDLA 1R0RI 3UGLA 1OMTA 3SGQI 2WVJA 2V53A 1TBOA 2YQPA 2GKTI 3UFFA 1UVGA 1XX6A 3OXFA 1TIHA 1LR9A 1CT0I 1SGRI 1PTRA 1X74A 1YTPA 1DS2I 1IY6A 1R79A 3UGDA 1XBTA 4A24A 1TURA 5JHWC 1OMUA 2ORVA 2ERWA 3UEYA 2SGDI 2J87A 3OXGA 1CT2I 2ORWA 2OVOA 4GI3C 2N1AB 2ARPF 2QQ0A 3GOXA 1SGEI 2P6AC 2VRWB 1AN1I 2FNFX 2A20A 1X4SA 3BJIA 4UXJA 2V1CA 4JCVE 2E5RA 2B0UC 1CT4I 3UGIA 2ENZA 2DIPA 2SGEI 3QTLD 2CJSC 1N13A 2GKRI 1V1HA 1Y1BA 2NU1I 2B8TA 2N17A 1U5KA 2NU3I 1BUSA 3VDUA 2E73A 3KY9A 3UEJA 2L8EA 2BUSA 2V1CC 2QPOA 4E1RA 2L7XA 1CE3A 3PDNA 1FYBA 2DB6A 2ELIA 2SGFI 1CGJI 3B4VC 2KMRA 1Y8FA 1SGPI 1OVOA 2K9HA 1V1IA 2LEOA 3OL0A 1W4RA 2J9RA 3FC3A 4SGBI 3OVOA 1CGII 1IY5A 2JZMA 2LUYA 1HPTA 1TUSA 2QQCA 2QQEA 5CCMA 4UXIA 5CCLA 1M8CA 5DAEA 1YU6C 1MT1A 1TOTA 4B6DA 1SGNI 1OYVI 1UVFA 1Y1CA 1PJUA 1H0ZA 1RFHA 2KMOA 2NU4I 4OVOA 1PPFI 2F3CI 2JA1A 2KMQA 1CSOI 1TBNA 2NU0I 3CXLA 4HGUA 3VDPA 4E1PA 5HQ8A 2KMPA 2QQDA 1FAQA 1NUBA 5FUXA 5EX3A 1BMOA 1SGYI 2XRCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UXH A;  2VRW B;  2FNF X;  3BJI A;  5FUV A;  1W4R A;  2GVI A;  4UXJ A;  2J9R A;  5FUY A;  3UGL A;  3UGI A;  2QQE A;  2WVJ A;  2ENZ A;  1TBO A;  4UXI A;  3UFF A;  1PTQ A;  1XA6 A;  1XX6 A;  5FUW A;  1PTR A;  4B6D A;  2B8T A;  1R79 A;  3UGD A;  1XBT A;  1KBF A;  1RFH A;  2E73 A;  3KY9 A;  3UEJ A;  2JA1 A;  1TBN A;  2QPO A;  3CXL A;  2ORV A;  3UEY A;  2J87 A;  3E2I A;  2ENN A;  2ROW A;  2DB6 A;  2ELI A;  2ORW A;  4L9M A;  5FUX A;  1FAQ A;  2UZ3 A;  1FAR A;  4FKD A;  1Y8F A;  1KBE A;  2YUU A;  2QQ0 A; 
#chains in the Genus database with same CATH topology
 1LR8 A;  3QWP A;  7WGA A;  1VDD A;  3SGB I;  1CHO I;  1TGS I;  2CWF A;  1LR7 A;  2GVI A;  2SGP I;  5FUY A;  1MJA A;  3RU0 A;  2LB7 A;  3D00 A;  2KCX A;  1PTQ A;  3SEK C;  1PCE A;  2M5X A;  1XA6 A;  2OD1 A;  2W0T A;  5FUW A;  1Z7K B;  1M8B A;  2WCY A;  2GKV A;  1K7U A;  1UHA A;  1SGD I;  2JYY A;  5EX0 A;  1KBF A;  1FY7 A;  2NU2 I;  2PQ8 A;  2JXD A;  3HH2 C;  1IW4 A;  1W3S A;  1UUC A;  3E2I A;  2ENN A;  2ROW A;  2SGQ I;  3OXL A;  5HI7 A;  4L9M A;  3TOB A;  2JW6 A;  3E59 A;  3VE5 A;  2UZ3 A;  1FAR A;  4FKD A;  1KBE A;  2YUU A;  3FSY A;  1KMA A;  2N71 A;  3TJQ A;  1ULM A;  4UXH A;  1DS3 I;  2ODD A;  1TBQ R;  1HJA I;  1ULK A;  2UVO A;  3MEK A;  1TBR R;  2N52 A;  2DKV A;  5FUV A;  1SGQ I;  1HDL A;  1MJ9 A;  1R0R I;  3UGL A;  1OMT A;  5E3Q A;  2WVJ A;  3SGQ I;  2V53 A;  1TBO A;  2YQP A;  3R5A A;  2GKT I;  3UFF A;  4AML A;  1UVG A;  1XX6 A;  3OXF A;  1TIH A;  1LR9 A;  1CT0 I;  1SGR I;  1PTR A;  1X74 A;  1YTP A;  1DS2 I;  1IY6 A;  1R79 A;  1WTJ A;  3UGD A;  1XBT A;  1K7T A;  4A24 A;  4DNC A;  1TUR A;  1IY5 A;  9WGA A;  1OMU A;  5JHW C;  5E3R A;  2ORV A;  2ERW A;  3UEY A;  2SGD I;  2J87 A;  3OXG A;  2WGC A;  1CT2 I;  2ORW A;  1P9Z A;  2OVO A;  4GI3 C;  1P9G A;  2N1A B;  2ARP F;  2X52 A;  2QQ0 A;  3GOX A;  1SGE I;  2P6A C;  2VRW B;  1AN1 I;  2FNF X;  2A20 A;  1S20 A;  1X4S A;  3BJI A;  3R5B A;  4UXJ A;  2V1C A;  4JCV E;  2E5R A;  2B0U C;  1CT4 I;  3TO9 A;  3UGI A;  2ENZ A;  2DIP A;  2SGE I;  3QTL D;  2CJS C;  1N13 A;  2GKR I;  3QAH A;  1V1H A;  1Y1B A;  2NU1 I;  2Y0M A;  4MPI A;  2B8T A;  2N17 A;  1U5K A;  1WGC A;  2NU3 I;  1BUS A;  3R5C A;  3VDU A;  3TOA A;  2E73 A;  3KY9 A;  3UEJ A;  2L8E A;  2BUS A;  2V1C C;  2QPO A;  4E1R A;  1WGT A;  2L7X A;  1CE3 A;  3PDN A;  3FSX A;  2OZU A;  3R5D A;  1FYB A;  4WP4 A;  2DB6 A;  2ELI A;  2SGF I;  1CGJ I;  3B4V C;  2KMR A;  1HEV A;  1Y8F A;  1SGP I;  3UOE A;  1OVO A;  2GIV A;  5J8F A;  2K9H A;  1V1I A;  3TO7 A;  1NXU A;  2LEO A;  3OL0 A;  1W4R A;  5E3P A;  2J9R A;  3FC3 A;  4SGB I;  1WKX A;  3OVO A;  1CGI I;  1Q9B A;  2JZM A;  2LUY A;  1HPT A;  1TUS A;  2CWG A;  2QQC A;  2QQE A;  4UXI A;  5CCM A;  5CCL A;  1M8C A;  2X3T A;  5DAE A;  2RIJ A;  1MJB A;  1TOT A;  1K7V A;  1MT1 A;  1YU6 C;  4B6D A;  1SGN I;  1OYV I;  1UVF A;  1Y1C A;  1PJU A;  1H0Z A;  1RFH A;  2KMO A;  2NU4 I;  1Z2I A;  4OVO A;  1PPF I;  2F3C I;  2JA1 A;  2KMQ A;  1CSO I;  1TBN A;  2NU0 I;  3CXL A;  4HGU A;  3VDP A;  4E1P A;  5HQ8 A;  2KMP A;  2OU2 A;  2QQD A;  1FAQ A;  2RC4 A;  1NUB A;  5FUX A;  5EX3 A;  1BMO A;  1ULN A;  3TO6 A;  5J8C A;  2CWH A;  1SGY I;  2XRC A; 
#chains in the Genus database with same CATH homology
 1LR8 A;  3QWP A;  1VDD A;  3SGB I;  1CHO I;  1TGS I;  1LR7 A;  2GVI A;  2SGP I;  5FUY A;  3RU0 A;  3D00 A;  2KCX A;  1PTQ A;  3SEK C;  1PCE A;  2M5X A;  1XA6 A;  2OD1 A;  2W0T A;  5FUW A;  1Z7K B;  1M8B A;  2WCY A;  2GKV A;  2JYY A;  1SGD I;  5EX0 A;  1KBF A;  2NU2 I;  2JXD A;  3HH2 C;  1IW4 A;  1W3S A;  1UUC A;  3E2I A;  2ENN A;  2ROW A;  2SGQ I;  3OXL A;  5HI7 A;  4L9M A;  3VE5 A;  2JW6 A;  3E59 A;  2UZ3 A;  1FAR A;  4FKD A;  1KBE A;  2YUU A;  1KMA A;  2N71 A;  3TJQ A;  4UXH A;  1DS3 I;  2ODD A;  1TBQ R;  1HJA I;  3MEK A;  1TBR R;  2N52 A;  5FUV A;  1SGQ I;  1HDL A;  1R0R I;  3UGL A;  1OMT A;  3SGQ I;  2WVJ A;  2V53 A;  1TBO A;  2YQP A;  2GKT I;  3UFF A;  1UVG A;  1XX6 A;  3OXF A;  1TIH A;  1LR9 A;  1CT0 I;  1SGR I;  1PTR A;  1X74 A;  1YTP A;  1DS2 I;  1IY6 A;  1R79 A;  3UGD A;  1XBT A;  4A24 A;  1TUR A;  5JHW C;  1OMU A;  2ORV A;  2ERW A;  3UEY A;  2SGD I;  2J87 A;  3OXG A;  1CT2 I;  2ORW A;  2OVO A;  4GI3 C;  2N1A B;  2ARP F;  2QQ0 A;  3GOX A;  1SGE I;  2P6A C;  2VRW B;  1AN1 I;  2FNF X;  2A20 A;  1X4S A;  3BJI A;  4UXJ A;  2V1C A;  4JCV E;  2E5R A;  2B0U C;  1CT4 I;  3UGI A;  2ENZ A;  2DIP A;  2SGE I;  3QTL D;  2CJS C;  1N13 A;  2GKR I;  1V1H A;  1Y1B A;  2NU1 I;  2B8T A;  2N17 A;  1U5K A;  2NU3 I;  1BUS A;  3VDU A;  2E73 A;  3KY9 A;  3UEJ A;  2L8E A;  2BUS A;  2V1C C;  2QPO A;  4E1R A;  2L7X A;  1CE3 A;  3PDN A;  1FYB A;  2DB6 A;  2ELI A;  2SGF I;  1CGJ I;  3B4V C;  2KMR A;  1Y8F A;  1SGP I;  1OVO A;  2K9H A;  1V1I A;  2LEO A;  3OL0 A;  1W4R A;  2J9R A;  3FC3 A;  4SGB I;  3OVO A;  1CGI I;  1IY5 A;  2JZM A;  2LUY A;  1HPT A;  1TUS A;  2QQC A;  2QQE A;  5CCM A;  4UXI A;  5CCL A;  1M8C A;  5DAE A;  1YU6 C;  1MT1 A;  1TOT A;  4B6D A;  1SGN I;  1OYV I;  1UVF A;  1Y1C A;  1PJU A;  1H0Z A;  1RFH A;  2KMO A;  2NU4 I;  4OVO A;  1PPF I;  2F3C I;  2JA1 A;  2KMQ A;  1CSO I;  1TBN A;  2NU0 I;  3CXL A;  4HGU A;  3VDP A;  4E1P A;  5HQ8 A;  2KMP A;  2QQD A;  1FAQ A;  1NUB A;  5FUX A;  5EX3 A;  1BMO A;  1SGY I;  2XRC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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