2P2MA

Acetyl-coa synthetase, r194a mutation
Total Genus 221
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
221
sequence length
643
structure length
638
Chain Sequence
HKHAIPANIADRCLINPEQYETKYKQSINDPDTFWGEQGKILDWITPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDTSQSKHISYRELHRDVCRFANTLLDLGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPEAVAGRIIDSSSRLVITADEGVRAGASIPLKKNVDDALKNPNVTSVEHVIVLKRTGSDIDWQEGRDLWWRDLIEKASPEHQPEAMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYAATTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVPNWPTPARMCQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINPEAWEWYWKKIGKEKCPVVDTWWQTETGGFMITPLPGAIELKAGSATRPFFGVQPALVDNEGHPQEGATEGNLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHAIKGQAIYAYVTLNHGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTSNTLADPGVVEKLLEEKQA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Acetyl-coenzyme A synthetase
publication title Biochemical and Crystallographic Analysis of Substrate Binding and Conformational Changes in Acetyl-CoA Synthetase.
pubmed doi rcsb
source organism Salmonella typhimurium
molecule tags Ligase
total genus 221
structure length 638
sequence length 643
chains with identical sequence B
ec nomenclature ec 6.2.1.1: Acetate--CoA ligase.
pdb deposition date 2007-03-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00501 AMP-binding AMP-binding enzyme
A PF13193 AMP-binding_C AMP-binding enzyme C-terminal domain
A PF16177 ACAS_N Acetyl-coenzyme A synthetase N-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.300.30 Alpha Beta 2-Layer Sandwich GMP Synthetase; Chain A, domain 3 GMP Synthetase; Chain A, domain 3 2p2mA02
2VZEA 4R1LA 5KYVA 4FUTA 1RY2A 4GS5A 4GXQA 3E7WA 5KEIA 4EATA 1LCIA 5KYTA 2WD9A 2P2BA 4G37A 4D56A 3G7SA 4RM2A 2Y4OA 4D4IA 5JRHA 4R0MA 3RG2A 2D1SA 4RMNA 1MD9A 5BSRA 1T5HX 3VNRA 2Y27A 1MDFA 1PG4A 2P2MA 2V7BA 4PZPA 4ISBA 3EQ6A 3IPLA 3L8CA 4D4GA 4ZJZA 1T5DX 4D57A 4RM3A 1YJ7A 4FUQA 5GTDA 3C5EA 2VSQA 5BSVA 5BURA 4DG9A 3ETCA 3NYQA 3R44A 4RLQA 5BSTA 5K85A 3DLPX 3GPCA 3CW9A 3A9UA 2P2JA 2D1TA 3B7WA 4IR7A 1PG3A 2P2QA 4OXIA 3LAXA 1BA3A 4WV3A 4GXRA 5IFIA 5BSWA 3A9VA 2P20A 4U5YD 4R1MA 4RLFA 2P2FA 4IZ6A 3VNSA 2D1QA 3FCCA 2QVZX 3VNQA 3DHVA 4RVNA 3PBKA 1ULTA 5BUSA 5BUQA 3DAYA 3E7XA 3LGXA 5K8FA 3LNVA 4RVOA 3NI2A 5E7QA 5DV9A 2D1RA 4DG8A 2Y4NA 1MDBA 2QVXX 3CW8X 4OYCA 5BSMA 4G36A 3KXWA 5BSUA 3FCEA 2QVYX 3NYRA 2QW0X 1AMUA
chains in the Genus database with same CATH superfamily
3TQIA 3CQ2A 1K0RA 1FJGC 1HH2P 4DR7C 4EATA 2ZZNA 4DV7C 5LCIA 3TR3A 4GKKC 4D56A 4FTFA 2E8FA 1N2FA 2ASBA 1P4EC 3RG2A 1WH9A 1ZB8A 5AE1A 2E0GA 2ONFA 4JM1A 1O90A 2HJGA 2P2MA 1XHJA 4LFCC 1RG9A 4ISBA 4LF4C 4JI7C 1T5DX 1MXCA 1MKYA 2P02A 4LE5A 4X64C 2OPLA 4DV5C 5BSVA 3T1YC 3NYQA 4JI0C 5K85A 5H9UA 2EGTA 4PUIA 2OPLB 2D1TA 4IR7A 4PROC 4JV5C 4LF6C 4JI5C 1WF3A 4LF8C 1BA3A 1XMOC 4WV3A 5BSWA 3IMLA 4JYAC 2MCQA 4U5YD 2VQFC 4ZLPA 3S82A 4I9GA 5A2QD 4IZ6A 5T8SA 3OTOC 4MTNA 1J5EC 2QVZX 2CU6A 3PBKA 1ULTA 3AF5A 5BR8C 3LGXA 3RV2A 3LNVA 1UWDA 4K0KC 1XNQC 2PT7G 5E7QA 4DCVA 1V26A 5A1IA 4DG8A 2Y4NA 1PU1A 1MDBA 2QVXX 4DR1C 3CW8X 5BSUA 4L4QA 2QVYX 4DV4C 4LFBC 1XS3A 2VZEA 4R1LA 2BH1X 4FUTA 4B3TC 4WS9A 2DPLA 4DV2C 5KYTA 4DR4C 1P4EA 2YWCA 2M5OA 2OO4A 4D4IA 1O92A 2DYJA 1T5HX 3VNRA 1MDFA 1KKGA 2MMAB 1I94C 2UUAC 4YHHC 4DUYC 2CY1A 3NPDA 2VQEC 4DV1C 4D4GA 1FLOA 4D57A 3R9XA 3CJEA 2UXBC 4RM3A 5A19A 1YJ7A 3C5EA 2D7VA 3ETCA 5BSTA 4DCTA 5T8TA 2ATWA 3DLPX 4KTTA 4JI4C 3A9UA 2D28C 2P2JA 1IBLC 1V60A 4PHTA 3LAXA 5ADZA 1IB8A 3I07A 2P20A 4R1MA 4RLFA 3J80D 2KZ0A 4G1IA 5LMNC 2D1QA 2JNVA 1XRCA 4PUHA 2YWBA 3FCCA 4HPVA 4RVNA 2E8CA 4DR5C 1ZB9A 5K8FA 1HR0C 4XX2A 4LFAC 2NCLA 2F4VC 3EERA 3SO4A 4TPSB 4GKJC 1HNWC 3FCEA 3CQ3A 2QW0X 1AMUA 2E5LC 4DV0C 3AF6A 3UOWA 1QWIA 3L95X 2HHHC 2KDNA 1RY2A 4GXQA 3E7WA 3GKUA 2CXCA 2WD9A 4G37A 4L2ZA 4K0BA 4RM2A 1WCJA 2Y4OA 4OX9C 2ZM6C 4DR2C 4RMNA 3GR0A 1MD9A 1VLAA 5BSRA 2PROA 4NXMC 1TH5A 1PG4A 1MXAA 4JI1C 2V7BA 3UX2A 4KTVA 3I08A 3IPLA 3UZ0A 4ZJZA 3AY0A 3T1HC 1HNZC 4DUZC 2YCBA 4MH4A 4FUQA 3O2EA 5GTDA 5BURA 1N34C 3R44A 4AQYC 1IBKC 4I9FA 1NY8A 3B7WA 3A4IA 4BC9A 3LNOA 1NYEA 4OXIA 2BJOA 4ODJA 5IFIA 3A9VA 4X66C 3ETOA 3GR1A 2KZFA 1PA4A 1N33C 3PROC 2P2FA 1GPMA 3K6RA 5A1GA 4NXNC 3DHVA 4JI6C 5BUQA 1O9TA 3E7XA 4DV3C 5CZVA 4BCAA 1XNRC 3NI2A 4JI3C 5AE3A 1VEHA 4DCUA 3N2QA 2UUCC 2D1RA 1ML8A 2UUBC 4B3MC 1EGAA 3A25A 4OYCA 5BSMA 3PESA 4B3SC 2AYAA 1IBMC 3NYRA 2D27A 2UXDC 2YX1A 4DCSA 5FLXD 3TDEA 4DR6C 2MM9A 1HNXC 4NOZA 4PUGA 5KYVA 3IEUA 4GS5A 4BBYA 1M6XC 5KEIA 1LCIA 1O93A 2P2BA 2M5HA 3G7SA 2JMPA 5JRHA 4YY3C 4R0MA 5LMUC 4X62C 2D1SA 2UXCC 1XRBA 5CZXA 4DR3C 2Y27A 4JI2C 1P7LA 2OBVA 4L7IA 2QL8A 4PZPA 4LF9C 1XMQC 3EQ6A 3L8CA 5IT9D 2E8EA 4NDNA 2VSQA 3J81D 2PN2A 4B3RC 4DG9A 4RLQA 3R9WA 2DHMA 4BC7A 3JAMD 2UU9C 3H2TA 3GPCA 3CW9A 1PG3A 2P2QA 2XR1A 3UX3A 4DV6C 4BSZA 4GXRA 1LQLA 1N36C 1XRAA 1N32C 5IWAC 3VNSA 3VNQA 5AE2A 3N54B 5BUSA 2E7GA 3DAYA 2Z51A 4LF7C 4RVOA 1L2FA 1V25A 2WP0C 3A26A 1USPA 5DV9A 3CQ1A 3IEVA 1QM4A 1UKKA 2ZZMA 1JOSA 1FUGA 4LF5C 4G36A 3KXWA 3UEBA 4JI8C 3TUFA 1USPB 1MXBA 4KHPC 4X65C 3LUSA 1M6XA
chains in the Genus database with same CATH topology
3TQIA 1K0RA 1FJGC 1HH2P 4DR7C 4EATA 4DV7C 4GKKC 4D56A 4FTFA 2E8FA 1N2FA 2ASBA 3RG2A 1WH9A 1ZB8A 5AE1A 2E0GA 2ONFA 4JM1A 1O90A 2HJGA 2P2MA 4LFCC 1RG9A 4ISBA 4LF4C 4JI7C 1T5DX 1MXCA 1MKYA 2P02A 4LE5A 4X64C 2OPLA 4DV5C 5BSVA 3T1YC 3NYQA 4JI0C 5K85A 5H9UA 2EGTA 2OPLB 2D1TA 4IR7A 4PROC 4JV5C 4LF6C 4JI5C 1WF3A 4LF8C 1BA3A 1XMOC 4WV3A 5BSWA 3IMLA 4JYAC 4U5YD 2VQFC 4ZLPA 3S82A 4I9GA 5A2QD 4IZ6A 5T8SA 3OTOC 4MTNA 1J5EC 2QVZX 3PBKA 1ULTA 3AF5A 5BR8C 3LGXA 3RV2A 3LNVA 4K0KC 1XNQC 2PT7G 5E7QA 4DCVA 1V26A 5A1IA 4DG8A 2Y4NA 1MDBA 2QVXX 4DR1C 3CW8X 5BSUA 4L4QA 2QVYX 4DV4C 4LFBC 2VZEA 4R1LA 2BH1X 4FUTA 4B3TC 4WS9A 2DPLA 4DV2C 5KYTA 4DR4C 2YWCA 2OO4A 4D4IA 1O92A 2DYJA 1T5HX 3VNRA 1MDFA 1KKGA 1I94C 2UUAC 4YHHC 4DUYC 2CY1A 3NPDA 2VQEC 4DV1C 4D4GA 4D57A 3R9XA 3CJEA 2UXBC 4RM3A 5A19A 1YJ7A 3C5EA 2D7VA 3ETCA 5BSTA 4DCTA 5T8TA 2ATWA 3DLPX 4KTTA 4JI4C 3A9UA 2D28C 2P2JA 1IBLC 4PHTA 3LAXA 5ADZA 3I07A 2P20A 4R1MA 4RLFA 3J80D 4G1IA 5LMNC 2D1QA 1XRCA 2YWBA 3FCCA 4HPVA 4RVNA 2E8CA 4DR5C 1ZB9A 5K8FA 1HR0C 4XX2A 4LFAC 2F4VC 3EERA 3SO4A 4TPSB 4GKJC 1HNWC 3FCEA 2QW0X 1AMUA 2E5LC 4DV0C 3AF6A 3UOWA 1QWIA 3L95X 2HHHC 1RY2A 4GXQA 3E7WA 3GKUA 2CXCA 2WD9A 4G37A 4L2ZA 4K0BA 4RM2A 2Y4OA 4OX9C 2ZM6C 4DR2C 4RMNA 3GR0A 1MD9A 1VLAA 5BSRA 2PROA 4NXMC 1PG4A 1MXAA 4JI1C 2V7BA 4KTVA 3I08A 3IPLA 3UZ0A 4ZJZA 3T1HC 1HNZC 4DUZC 2YCBA 4MH4A 4FUQA 5GTDA 5BURA 1N34C 3R44A 4AQYC 1IBKC 4I9FA 3B7WA 3A4IA 4BC9A 1NYEA 4OXIA 2BJOA 4ODJA 5IFIA 3A9VA 4X66C 3ETOA 3GR1A 2KZFA 1PA4A 1N33C 3PROC 2P2FA 1GPMA 5A1GA 4NXNC 3DHVA 4JI6C 5BUQA 1O9TA 3E7XA 4DV3C 5CZVA 4BCAA 1XNRC 3NI2A 4JI3C 5AE3A 4DCUA 3N2QA 2UUCC 2D1RA 1ML8A 2UUBC 4B3MC 1EGAA 4OYCA 5BSMA 3PESA 4B3SC 2AYAA 1IBMC 3NYRA 2D27A 2UXDC 4DCSA 5FLXD 3TDEA 4DR6C 1HNXC 4NOZA 5KYVA 3IEUA 4GS5A 4BBYA 5KEIA 1LCIA 1O93A 2P2BA 3G7SA 2JMPA 5JRHA 4YY3C 4R0MA 5LMUC 4X62C 2D1SA 2UXCC 1XRBA 5CZXA 4DR3C 2Y27A 4JI2C 1P7LA 2OBVA 4L7IA 2QL8A 4PZPA 4LF9C 1XMQC 3EQ6A 3L8CA 5IT9D 2E8EA 4NDNA 2VSQA 3J81D 2PN2A 4B3RC 4DG9A 4RLQA 3R9WA 4BC7A 3JAMD 2UU9C 3H2TA 3GPCA 3CW9A 1PG3A 2P2QA 2XR1A 4DV6C 4BSZA 4GXRA 1LQLA 1N36C 1XRAA 1N32C 5IWAC 3VNSA 3VNQA 5AE2A 3N54B 5BUSA 2E7GA 3DAYA 4LF7C 4RVOA 1L2FA 1V25A 2WP0C 1USPA 5DV9A 3IEVA 1QM4A 1UKKA 1JOSA 1FUGA 4LF5C 4G36A 3KXWA 4JI8C 3TUFA 1USPB 1MXBA 4KHPC 4X65C 3LUSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VZE A;  4R1L A;  5KYV A;  4FUT A;  1RY2 A;  4GS5 A;  4GXQ A;  3E7W A;  5KEI A;  4EAT A;  1LCI A;  5KYT A;  2WD9 A;  2P2B A;  4G37 A;  4D56 A;  3G7S A;  4RM2 A;  2Y4O A;  4D4I A;  5JRH A;  4R0M A;  3RG2 A;  2D1S A;  4RMN A;  1MD9 A;  5BSR A;  1T5H X;  3VNR A;  2Y27 A;  1MDF A;  1PG4 A;  2P2M A;  2V7B A;  4PZP A;  4ISB A;  3EQ6 A;  3IPL A;  3L8C A;  4D4G A;  4ZJZ A;  1T5D X;  4D57 A;  4RM3 A;  1YJ7 A;  4FUQ A;  5GTD A;  3C5E A;  2VSQ A;  5BSV A;  5BUR A;  4DG9 A;  3ETC A;  3NYQ A;  3R44 A;  4RLQ A;  5BST A;  5K85 A;  3DLP X;  3GPC A;  3CW9 A;  3A9U A;  2P2J A;  2D1T A;  3B7W A;  4IR7 A;  1PG3 A;  2P2Q A;  4OXI A;  3LAX A;  1BA3 A;  4WV3 A;  4GXR A;  5IFI A;  5BSW A;  3A9V A;  2P20 A;  4U5Y D;  4R1M A;  4RLF A;  2P2F A;  4IZ6 A;  3VNS A;  2D1Q A;  3FCC A;  2QVZ X;  3VNQ A;  3DHV A;  4RVN A;  3PBK A;  1ULT A;  5BUS A;  5BUQ A;  3DAY A;  3E7X A;  3LGX A;  5K8F A;  3LNV A;  4RVO A;  3NI2 A;  5E7Q A;  5DV9 A;  2D1R A;  4DG8 A;  2Y4N A;  1MDB A;  2QVX X;  3CW8 X;  4OYC A;  5BSM A;  4G36 A;  3KXW A;  5BSU A;  3FCE A;  2QVY X;  3NYR A;  2QW0 X;  1AMU A; 
#chains in the Genus database with same CATH topology
 3TQI A;  3CQ2 A;  1K0R A;  1FJG C;  1HH2 P;  4DR7 C;  4EAT A;  2ZZN A;  4DV7 C;  5LCI A;  3TR3 A;  4GKK C;  4D56 A;  4FTF A;  2E8F A;  1N2F A;  2ASB A;  1P4E C;  3RG2 A;  1WH9 A;  1ZB8 A;  5AE1 A;  2E0G A;  2ONF A;  4JM1 A;  1O90 A;  2HJG A;  2P2M A;  1XHJ A;  4LFC C;  1RG9 A;  4ISB A;  4LF4 C;  4JI7 C;  1T5D X;  1MXC A;  1MKY A;  2P02 A;  4LE5 A;  4X64 C;  2OPL A;  4DV5 C;  5BSV A;  3T1Y C;  3NYQ A;  4JI0 C;  5K85 A;  5H9U A;  2EGT A;  4PUI A;  2OPL B;  2D1T A;  4IR7 A;  4PRO C;  4JV5 C;  4LF6 C;  4JI5 C;  1WF3 A;  4LF8 C;  1BA3 A;  1XMO C;  4WV3 A;  5BSW A;  3IML A;  4JYA C;  2MCQ A;  4U5Y D;  2VQF C;  4ZLP A;  3S82 A;  4I9G A;  5A2Q D;  4IZ6 A;  5T8S A;  3OTO C;  4MTN A;  1J5E C;  2QVZ X;  2CU6 A;  3PBK A;  1ULT A;  3AF5 A;  5BR8 C;  3LGX A;  3RV2 A;  3LNV A;  1UWD A;  4K0K C;  1XNQ C;  2PT7 G;  5E7Q A;  4DCV A;  1V26 A;  5A1I A;  4DG8 A;  2Y4N A;  1PU1 A;  1MDB A;  2QVX X;  4DR1 C;  3CW8 X;  5BSU A;  4L4Q A;  2QVY X;  4DV4 C;  4LFB C;  1XS3 A;  2VZE A;  4R1L A;  2BH1 X;  4FUT A;  4B3T C;  4WS9 A;  2DPL A;  4DV2 C;  5KYT A;  4DR4 C;  1P4E A;  2YWC A;  2M5O A;  2OO4 A;  4D4I A;  1O92 A;  2DYJ A;  1T5H X;  3VNR A;  1MDF A;  1KKG A;  2MMA B;  1I94 C;  2UUA C;  4YHH C;  4DUY C;  2CY1 A;  3NPD A;  2VQE C;  4DV1 C;  4D4G A;  1FLO A;  4D57 A;  3R9X A;  3CJE A;  2UXB C;  4RM3 A;  5A19 A;  1YJ7 A;  3C5E A;  2D7V A;  3ETC A;  5BST A;  4DCT A;  5T8T A;  2ATW A;  3DLP X;  4KTT A;  4JI4 C;  3A9U A;  2D28 C;  2P2J A;  1IBL C;  1V60 A;  4PHT A;  3LAX A;  5ADZ A;  1IB8 A;  3I07 A;  2P20 A;  4R1M A;  4RLF A;  3J80 D;  2KZ0 A;  4G1I A;  5LMN C;  2D1Q A;  2JNV A;  1XRC A;  4PUH A;  2YWB A;  3FCC A;  4HPV A;  4RVN A;  2E8C A;  4DR5 C;  1ZB9 A;  5K8F A;  1HR0 C;  4XX2 A;  4LFA C;  2NCL A;  2F4V C;  3EER A;  3SO4 A;  4TPS B;  4GKJ C;  1HNW C;  3FCE A;  3CQ3 A;  2QW0 X;  1AMU A;  2E5L C;  4DV0 C;  3AF6 A;  3UOW A;  1QWI A;  3L95 X;  2HHH C;  2KDN A;  1RY2 A;  4GXQ A;  3E7W A;  3GKU A;  2CXC A;  2WD9 A;  4G37 A;  4L2Z A;  4K0B A;  4RM2 A;  1WCJ A;  2Y4O A;  4OX9 C;  2ZM6 C;  4DR2 C;  4RMN A;  3GR0 A;  1MD9 A;  1VLA A;  5BSR A;  2PRO A;  4NXM C;  1TH5 A;  1PG4 A;  1MXA A;  4JI1 C;  2V7B A;  3UX2 A;  4KTV A;  3I08 A;  3IPL A;  3UZ0 A;  4ZJZ A;  3AY0 A;  3T1H C;  1HNZ C;  4DUZ C;  2YCB A;  4MH4 A;  4FUQ A;  3O2E A;  5GTD A;  5BUR A;  1N34 C;  3R44 A;  4AQY C;  1IBK C;  4I9F A;  1NY8 A;  3B7W A;  3A4I A;  4BC9 A;  3LNO A;  1NYE A;  4OXI A;  2BJO A;  4ODJ A;  5IFI A;  3A9V A;  4X66 C;  3ETO A;  3GR1 A;  2KZF A;  1PA4 A;  1N33 C;  3PRO C;  2P2F A;  1GPM A;  3K6R A;  5A1G A;  4NXN C;  3DHV A;  4JI6 C;  5BUQ A;  1O9T A;  3E7X A;  4DV3 C;  5CZV A;  4BCA A;  1XNR C;  3NI2 A;  4JI3 C;  5AE3 A;  1VEH A;  4DCU A;  3N2Q A;  2UUC C;  2D1R A;  1ML8 A;  2UUB C;  4B3M C;  1EGA A;  3A25 A;  4OYC A;  5BSM A;  3PES A;  4B3S C;  2AYA A;  1IBM C;  3NYR A;  2D27 A;  2UXD C;  2YX1 A;  4DCS A;  5FLX D;  3TDE A;  4DR6 C;  2MM9 A;  1HNX C;  4NOZ A;  4PUG A;  5KYV A;  3IEU A;  4GS5 A;  4BBY A;  1M6X C;  5KEI A;  1LCI A;  1O93 A;  2P2B A;  2M5H A;  3G7S A;  2JMP A;  5JRH A;  4YY3 C;  4R0M A;  5LMU C;  4X62 C;  2D1S A;  2UXC C;  1XRB A;  5CZX A;  4DR3 C;  2Y27 A;  4JI2 C;  1P7L A;  2OBV A;  4L7I A;  2QL8 A;  4PZP A;  4LF9 C;  1XMQ C;  3EQ6 A;  3L8C A;  5IT9 D;  2E8E A;  4NDN A;  2VSQ A;  3J81 D;  2PN2 A;  4B3R C;  4DG9 A;  4RLQ A;  3R9W A;  2DHM A;  4BC7 A;  3JAM D;  2UU9 C;  3H2T A;  3GPC A;  3CW9 A;  1PG3 A;  2P2Q A;  2XR1 A;  3UX3 A;  4DV6 C;  4BSZ A;  4GXR A;  1LQL A;  1N36 C;  1XRA A;  1N32 C;  5IWA C;  3VNS A;  3VNQ A;  5AE2 A;  3N54 B;  5BUS A;  2E7G A;  3DAY A;  2Z51 A;  4LF7 C;  4RVO A;  1L2F A;  1V25 A;  2WP0 C;  3A26 A;  1USP A;  5DV9 A;  3CQ1 A;  3IEV A;  1QM4 A;  1UKK A;  2ZZM A;  1JOS A;  1FUG A;  4LF5 C;  4G36 A;  3KXW A;  3UEB A;  4JI8 C;  3TUF A;  1USP B;  1MXB A;  4KHP C;  4X65 C;  3LUS A;  1M6X A; 
#chains in the Genus database with same CATH homology
 3TQI A;  1K0R A;  1FJG C;  1HH2 P;  4DR7 C;  4EAT A;  4DV7 C;  4GKK C;  4D56 A;  4FTF A;  2E8F A;  1N2F A;  2ASB A;  3RG2 A;  1WH9 A;  1ZB8 A;  5AE1 A;  2E0G A;  2ONF A;  4JM1 A;  1O90 A;  2HJG A;  2P2M A;  4LFC C;  1RG9 A;  4ISB A;  4LF4 C;  4JI7 C;  1T5D X;  1MXC A;  1MKY A;  2P02 A;  4LE5 A;  4X64 C;  2OPL A;  4DV5 C;  5BSV A;  3T1Y C;  3NYQ A;  4JI0 C;  5K85 A;  5H9U A;  2EGT A;  2OPL B;  2D1T A;  4IR7 A;  4PRO C;  4JV5 C;  4LF6 C;  4JI5 C;  1WF3 A;  4LF8 C;  1BA3 A;  1XMO C;  4WV3 A;  5BSW A;  3IML A;  4JYA C;  4U5Y D;  2VQF C;  4ZLP A;  3S82 A;  4I9G A;  5A2Q D;  4IZ6 A;  5T8S A;  3OTO C;  4MTN A;  1J5E C;  2QVZ X;  3PBK A;  1ULT A;  3AF5 A;  5BR8 C;  3LGX A;  3RV2 A;  3LNV A;  4K0K C;  1XNQ C;  2PT7 G;  5E7Q A;  4DCV A;  1V26 A;  5A1I A;  4DG8 A;  2Y4N A;  1MDB A;  2QVX X;  4DR1 C;  3CW8 X;  5BSU A;  4L4Q A;  2QVY X;  4DV4 C;  4LFB C;  2VZE A;  4R1L A;  2BH1 X;  4FUT A;  4B3T C;  4WS9 A;  2DPL A;  4DV2 C;  5KYT A;  4DR4 C;  2YWC A;  2OO4 A;  4D4I A;  1O92 A;  2DYJ A;  1T5H X;  3VNR A;  1MDF A;  1KKG A;  1I94 C;  2UUA C;  4YHH C;  4DUY C;  2CY1 A;  3NPD A;  2VQE C;  4DV1 C;  4D4G A;  4D57 A;  3R9X A;  3CJE A;  2UXB C;  4RM3 A;  5A19 A;  1YJ7 A;  3C5E A;  2D7V A;  3ETC A;  5BST A;  4DCT A;  5T8T A;  2ATW A;  3DLP X;  4KTT A;  4JI4 C;  3A9U A;  2D28 C;  2P2J A;  1IBL C;  4PHT A;  3LAX A;  5ADZ A;  3I07 A;  2P20 A;  4R1M A;  4RLF A;  3J80 D;  4G1I A;  5LMN C;  2D1Q A;  1XRC A;  2YWB A;  3FCC A;  4HPV A;  4RVN A;  2E8C A;  4DR5 C;  1ZB9 A;  5K8F A;  1HR0 C;  4XX2 A;  4LFA C;  2F4V C;  3EER A;  3SO4 A;  4TPS B;  4GKJ C;  1HNW C;  3FCE A;  2QW0 X;  1AMU A;  2E5L C;  4DV0 C;  3AF6 A;  3UOW A;  1QWI A;  3L95 X;  2HHH C;  1RY2 A;  4GXQ A;  3E7W A;  3GKU A;  2CXC A;  2WD9 A;  4G37 A;  4L2Z A;  4K0B A;  4RM2 A;  2Y4O A;  4OX9 C;  2ZM6 C;  4DR2 C;  4RMN A;  3GR0 A;  1MD9 A;  1VLA A;  5BSR A;  2PRO A;  4NXM C;  1PG4 A;  1MXA A;  4JI1 C;  2V7B A;  4KTV A;  3I08 A;  3IPL A;  3UZ0 A;  4ZJZ A;  3T1H C;  1HNZ C;  4DUZ C;  2YCB A;  4MH4 A;  4FUQ A;  5GTD A;  5BUR A;  1N34 C;  3R44 A;  4AQY C;  1IBK C;  4I9F A;  3B7W A;  3A4I A;  4BC9 A;  1NYE A;  4OXI A;  2BJO A;  4ODJ A;  5IFI A;  3A9V A;  4X66 C;  3ETO A;  3GR1 A;  2KZF A;  1PA4 A;  1N33 C;  3PRO C;  2P2F A;  1GPM A;  5A1G A;  4NXN C;  3DHV A;  4JI6 C;  5BUQ A;  1O9T A;  3E7X A;  4DV3 C;  5CZV A;  4BCA A;  1XNR C;  3NI2 A;  4JI3 C;  5AE3 A;  4DCU A;  3N2Q A;  2UUC C;  2D1R A;  1ML8 A;  2UUB C;  4B3M C;  1EGA A;  4OYC A;  5BSM A;  3PES A;  4B3S C;  2AYA A;  1IBM C;  3NYR A;  2D27 A;  2UXD C;  4DCS A;  5FLX D;  3TDE A;  4DR6 C;  1HNX C;  4NOZ A;  5KYV A;  3IEU A;  4GS5 A;  4BBY A;  5KEI A;  1LCI A;  1O93 A;  2P2B A;  3G7S A;  2JMP A;  5JRH A;  4YY3 C;  4R0M A;  5LMU C;  4X62 C;  2D1S A;  2UXC C;  1XRB A;  5CZX A;  4DR3 C;  2Y27 A;  4JI2 C;  1P7L A;  2OBV A;  4L7I A;  2QL8 A;  4PZP A;  4LF9 C;  1XMQ C;  3EQ6 A;  3L8C A;  5IT9 D;  2E8E A;  4NDN A;  2VSQ A;  3J81 D;  2PN2 A;  4B3R C;  4DG9 A;  4RLQ A;  3R9W A;  4BC7 A;  3JAM D;  2UU9 C;  3H2T A;  3GPC A;  3CW9 A;  1PG3 A;  2P2Q A;  2XR1 A;  4DV6 C;  4BSZ A;  4GXR A;  1LQL A;  1N36 C;  1XRA A;  1N32 C;  5IWA C;  3VNS A;  3VNQ A;  5AE2 A;  3N54 B;  5BUS A;  2E7G A;  3DAY A;  4LF7 C;  4RVO A;  1L2F A;  1V25 A;  2WP0 C;  1USP A;  5DV9 A;  3IEV A;  1QM4 A;  1UKK A;  1JOS A;  1FUG A;  4LF5 C;  4G36 A;  3KXW A;  4JI8 C;  3TUF A;  1USP B;  1MXB A;  4KHP C;  4X65 C;  3LUS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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