1XSZA

The structure of ralf
Total Genus 129
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
129
sequence length
356
structure length
356
Chain Sequence
GASHPEIEKAQREIIEAFNAKPKNGINKIKEICEQYKISPNEEIAEFFHQQRKNLDLEAVGDYLSSPEAENQQVLKAFTSQMNFNGQSFVEGLRTFLKTFKLPGEAQKIDRLVQSFSGAYFQQNPDVVSNADAAYLLAFQTIMLNTDLHNPSIPEKNKMTVDGLKRNLRGGNNGGDFDAKFLEELYSEIKAKPFELNFVKTSPGYELTSTTLNKDSTFKKLDSFLHSTDVNINTVFPGIGDNVKTTVDQPKSWLSFFTGYKGTITLTDNKTSAQATIQVYTPNIFSKWLFGEQPRVIIQPGQTKESIDLAAKAAADFSSPVKNFKATYDYEVGDLIKAYDNQKKLITIERNLALKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of RalF, an ADP-ribosylation factor guanine nucleotide exchange factor from Legionella pneumophila, reveals the presence of a cap over the active site
pubmed doi rcsb
molecule tags Signaling protein
source organism Legionella pneumophila
molecule keywords guanine nucleotide exchange protein
total genus 129
structure length 356
sequence length 356
chains with identical sequence B
ec nomenclature
pdb deposition date 2004-10-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01369 Sec7 Sec7 domain
A PF18248 RalF_SCD RalF C-terminal Sec-7 capping domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.20 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin V; domain 1 1xszA01
1.10.1000.11 Mainly Alpha Orthogonal Bundle Arf Nucleotide-binding Site Opener; domain 2 Arf Nucleotide-binding Site Opener,domain 2 1xszA02
3.30.310.140 Alpha Beta 2-Layer Sandwich TATA-Binding Protein sec7 domains 1xszA03
2R09A 1RE0B 4L5MA 4C7PA 3L8NA 4D7QA 1R8QE 4OIYA 4A4PA 1PBVA 4JMIA 3LTLA 1BC9A 4JMOA 1R8ME 4C0AA 2R0DA 1R8SE 1S9DE 1XSZA 3SWVA 4JXHA 1XT0B 4JWLA 4D7RA 1KU1A 4Z21A
chains in the Genus database with same CATH superfamily
2IE7A 1PZDA 1YTBA 1YQKA 1AEIA 1YQMA 3OLPA 3ANYA 1WJWA 2JOIA 5IYCP 1NVPA 1KFQA 2NLVA 2IV9A 1R8SE 2D0BA 2FKMX 1N39A 1R4XA 3I0WA 3VN5A 2QRDA 3HS9A 1M5Q1 1HM6A 1W80A 3EAYA 1W3WA 3ULXA 2NWVA 3KTUA 3AJCA 2HYVA 3EIKA 1XT0B 1E42A 2NOBA 2DKCA 1ANNA 4IL8A 2OOXA 4EVFA 3HJLA 4MDUA 1BC1A 2NVMA 3ENCA 2NOZA 1UPTB 1XJLA 1NGMA 1R4AE 1C4GA 2NOLA 1QTSA 1HVFA 1UL7A 4JXHA 5HSHA 2DKDA 2HL9A 1N00A 1KY6A 2HYUA 4EAKA 1FN7A 5AN4A 1DIZA 1YTFA 4C0AA 1CDWA 1QN8A 2H5AX 3C04A 1KFIA 3OSEA 1T6AA 4EAJA 1MP9A 4L5MA 4D7QA 3L8NA 3RPJA 1BC3A 2NOHA 2HKPA 4RODB 3D7QA 4X9PA 3OCIA 1BO9A 2OOYA 3DPTA 1LWVA 1QN4A 1JFIC 3CWUA 2V9JA 3CVSA 1KYDA 1QC7A 3BKQX 1KYFA 1PBVA 1HAKA 1D3UA 4KN7X 2V92A 2VJ0A 3UW2A 2Y8LA 4Q2SA 4MDVA 1QN3A 1AVHA 2NOIA 2HL8A 1P5GX 1TBAB 1I4AA 2QLVA 5IYDP 1N41A 1PVSA 4C7PA 2G30A 4ROEB 1ALAA 2QR1A 1PCMX 1SAVA 1HVGA 1BCWA 3I3WA 3ABRA 1AISA 4MRQA 4WXAA 2H0MA 4EVHA 3T4NA 1B9KA 2HZMA 1VOLB 1QNAA 1BCZA 1LWWA 2MJ7A 2ZOCA 1Q8DA 1QN5A 3OC3C 2V8QA 1K2YX 1MCXA 3RSMA 1EUVA 1G5NA 4Q11A 1QN9A 1QNCA 1S9DE 2HSNA 1PCJX 4PY5A 4JK1X 2O3OA 3SOHB 1M3QA 2YH5A 2I5WA 3N89A 1J3MA 1JDYA 2ZHJA 1LXTA 1Q9UA 2ZHIA 3TDHA 1VKLA 4EAGA 2Y8QA 3SNSA 1QNEA 1QTPA 1HVEA 1PCZA 1N3CA 3ABQA 1P5DX 1N42A 3HS8A 1BCYA 2IV8A 2DKAA 1NH2A 1R8QE 1M9IA 3ABOA 1YQRA 3TE5A 2VXGA 5BMNA 1R8ME 2Z0FA 2ZFDB 2JHJA 1YQLA 2F7LA 4KMUX 3OSTA 1VOKA 1N44A 1N3AA 1K35A 3OSMA 3I0XA 2NOEA 2LAEA 1HVDA 1RE0B 1V5SA 1TBPA 4FQ0C 2RANA 2NOFA 3D4VA 3USYA 4EALA 1C1KA 3DPUA 4HJHA 5KL0A 1W7BA 3AO0A 4EJYA 4KN4X 1KU1A 4Z21A 2JPIA 2R09A 2D0AA 2PWWA 3PMGA 2D0CA 3ASMA 2IE6A 3OGDA 2HYWA 1HU0A 3CWTA 2XHIA 2IICA 3OH6A 5JMVD 1M3HA 3USWA 1UT7A 1VTLE 1EBMA 3CVTA 4CFFA 2EHBD 2Q4CA 1A8AA 3NA5A 2YA3A 1W45A 1WQAA 4WX8A 1DK5A 4ROCB 2H0LA 3LTLA 2JHNA 2II2A 2R5XA 1TUOA 1BC9A 5EPCA 2R0DA 3CWAA 2K6XA 5F9CA 3CWSA 1AVCA 1XSZA 3ABSA 3KRMA 2FGTA 1AVRA 1VTOA 1UT4A 2QRCA 5BMPA 4A4PA 1YJ0A 2Z8UA 3ENOC 3TW5A 3CW7A 1YCNA 4JMOA 4I8OA 2XO3A 4QG5A 3IH7A 1ANXA 1MPGA 3OH9A 4WZSD 3BRXA 4JWLA 3F10A 1BC0A 2FKFA 4TPSA 1ANWA 2H0KA 4DULA 1AOWA 1YIIA 1YGMA 1AXNA 4JMIA 1AIIA 1A8BA 1DM5A 4HREA 3PDKA 1LWYA 1KO9A 2MZ8A 4EAIA 3SWVA 1C47A 4B0AA 4BJUA 4FHRB 5JN5A 2QREA 4EJZA 2FUVA 2HZSA 4OIYA 1TGHA 1RM1A 2H4LX 2OY9A 1KY7A 1KYUA 1C9BB 3F0ZA 1LKVX 2QEZA 5IYBP 1QN7A 1QN6A 1QNBA 3H1ZA 4D7RA 2XO2A
chains in the Genus database with same CATH topology
1Q8DA 2R09A 1QC7A 3HJLA 1RE0B 4L5MA 4C7PA 3L8NA 4D7QA 1R8QE 4OIYA 4A4PA 1PBVA 4FQ0C 4JMIA 3TW5A 3LTLA 4KN7X 1BC9A 4JMOA 3USYA 1R8ME 4C0AA 2R0DA 3AJCA 2K6XA 3USWA 1R8SE 1S9DE 2HSNA 1XSZA 4KMUX 3SWVA 1LKVX 4JXHA 1XT0B 4JWLA 4JK1X 4D7RA 4KN4X 1KU1A 4Z21A 4FHRB 3SOHB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R09 A;  1RE0 B;  4L5M A;  4C7P A;  3L8N A;  4D7Q A;  1R8Q E;  4OIY A;  4A4P A;  1PBV A;  4JMI A;  3LTL A;  1BC9 A;  4JMO A;  1R8M E;  4C0A A;  2R0D A;  1R8S E;  1S9D E;  1XSZ A;  3SWV A;  4JXH A;  1XT0 B;  4JWL A;  4D7R A;  1KU1 A;  4Z21 A; 
#chains in the Genus database with same CATH topology
 2IE7 A;  1PZD A;  1YTB A;  1YQK A;  1AEI A;  1YQM A;  3OLP A;  3ANY A;  1WJW A;  2JOI A;  5IYC P;  1NVP A;  1KFQ A;  2NLV A;  2IV9 A;  1R8S E;  2D0B A;  2FKM X;  1N39 A;  1R4X A;  3I0W A;  3VN5 A;  2QRD A;  3HS9 A;  1M5Q 1;  1HM6 A;  1W80 A;  3EAY A;  1W3W A;  3ULX A;  2NWV A;  3KTU A;  3AJC A;  2HYV A;  3EIK A;  1XT0 B;  1E42 A;  2NOB A;  2DKC A;  1ANN A;  4IL8 A;  2OOX A;  4EVF A;  3HJL A;  4MDU A;  1BC1 A;  2NVM A;  3ENC A;  2NOZ A;  1UPT B;  1XJL A;  1NGM A;  1R4A E;  1C4G A;  2NOL A;  1QTS A;  1HVF A;  1UL7 A;  4JXH A;  5HSH A;  2DKD A;  2HL9 A;  1N00 A;  1KY6 A;  2HYU A;  4EAK A;  1FN7 A;  5AN4 A;  1DIZ A;  1YTF A;  4C0A A;  1CDW A;  1QN8 A;  2H5A X;  3C04 A;  1KFI A;  3OSE A;  1T6A A;  4EAJ A;  1MP9 A;  4L5M A;  4D7Q A;  3L8N A;  3RPJ A;  1BC3 A;  2NOH A;  2HKP A;  4ROD B;  3D7Q A;  4X9P A;  3OCI A;  1BO9 A;  2OOY A;  3DPT A;  1LWV A;  1QN4 A;  1JFI C;  3CWU A;  2V9J A;  3CVS A;  1KYD A;  1QC7 A;  3BKQ X;  1KYF A;  1PBV A;  1HAK A;  1D3U A;  4KN7 X;  2V92 A;  2VJ0 A;  3UW2 A;  2Y8L A;  4Q2S A;  4MDV A;  1QN3 A;  1AVH A;  2NOI A;  2HL8 A;  1P5G X;  1TBA B;  1I4A A;  2QLV A;  5IYD P;  1N41 A;  1PVS A;  4C7P A;  2G30 A;  4ROE B;  1ALA A;  2QR1 A;  1PCM X;  1SAV A;  1HVG A;  1BCW A;  3I3W A;  3ABR A;  1AIS A;  4MRQ A;  4WXA A;  2H0M A;  4EVH A;  3T4N A;  1B9K A;  2HZM A;  1VOL B;  1QNA A;  1BCZ A;  1LWW A;  2MJ7 A;  2ZOC A;  1Q8D A;  1QN5 A;  3OC3 C;  2V8Q A;  1K2Y X;  1MCX A;  3RSM A;  1EUV A;  1G5N A;  4Q11 A;  1QN9 A;  1QNC A;  1S9D E;  2HSN A;  1PCJ X;  4PY5 A;  4JK1 X;  2O3O A;  3SOH B;  1M3Q A;  2YH5 A;  2I5W A;  3N89 A;  1J3M A;  1JDY A;  2ZHJ A;  1LXT A;  1Q9U A;  2ZHI A;  3TDH A;  1VKL A;  4EAG A;  2Y8Q A;  3SNS A;  1QNE A;  1QTP A;  1HVE A;  1PCZ A;  1N3C A;  3ABQ A;  1P5D X;  1N42 A;  3HS8 A;  1BCY A;  2IV8 A;  2DKA A;  1NH2 A;  1R8Q E;  1M9I A;  3ABO A;  1YQR A;  3TE5 A;  2VXG A;  5BMN A;  1R8M E;  2Z0F A;  2ZFD B;  2JHJ A;  1YQL A;  2F7L A;  4KMU X;  3OST A;  1VOK A;  1N44 A;  1N3A A;  1K35 A;  3OSM A;  3I0X A;  2NOE A;  2LAE A;  1HVD A;  1RE0 B;  1V5S A;  1TBP A;  4FQ0 C;  2RAN A;  2NOF A;  3D4V A;  3USY A;  4EAL A;  1C1K A;  3DPU A;  4HJH A;  5KL0 A;  1W7B A;  3AO0 A;  4EJY A;  4KN4 X;  1KU1 A;  4Z21 A;  2JPI A;  2R09 A;  2D0A A;  2PWW A;  3PMG A;  2D0C A;  3ASM A;  2IE6 A;  3OGD A;  2HYW A;  1HU0 A;  3CWT A;  2XHI A;  2IIC A;  3OH6 A;  5JMV D;  1M3H A;  3USW A;  1UT7 A;  1VTL E;  1EBM A;  3CVT A;  4CFF A;  2EHB D;  2Q4C A;  1A8A A;  3NA5 A;  2YA3 A;  1W45 A;  1WQA A;  4WX8 A;  1DK5 A;  4ROC B;  2H0L A;  3LTL A;  2JHN A;  2II2 A;  2R5X A;  1TUO A;  1BC9 A;  5EPC A;  2R0D A;  3CWA A;  2K6X A;  5F9C A;  3CWS A;  1AVC A;  1XSZ A;  3ABS A;  3KRM A;  2FGT A;  1AVR A;  1VTO A;  1UT4 A;  2QRC A;  5BMP A;  4A4P A;  1YJ0 A;  2Z8U A;  3ENO C;  3TW5 A;  3CW7 A;  1YCN A;  4JMO A;  4I8O A;  2XO3 A;  4QG5 A;  3IH7 A;  1ANX A;  1MPG A;  3OH9 A;  4WZS D;  3BRX A;  4JWL A;  3F10 A;  1BC0 A;  2FKF A;  4TPS A;  1ANW A;  2H0K A;  4DUL A;  1AOW A;  1YII A;  1YGM A;  1AXN A;  4JMI A;  1AII A;  1A8B A;  1DM5 A;  4HRE A;  3PDK A;  1LWY A;  1KO9 A;  2MZ8 A;  4EAI A;  3SWV A;  1C47 A;  4B0A A;  4BJU A;  4FHR B;  5JN5 A;  2QRE A;  4EJZ A;  2FUV A;  2HZS A;  4OIY A;  1TGH A;  1RM1 A;  2H4L X;  2OY9 A;  1KY7 A;  1KYU A;  1C9B B;  3F0Z A;  1LKV X;  2QEZ A;  5IYB P;  1QN7 A;  1QN6 A;  1QNB A;  3H1Z A;  4D7R A;  2XO2 A; 
#chains in the Genus database with same CATH homology
 1Q8D A;  2R09 A;  1QC7 A;  3HJL A;  1RE0 B;  4L5M A;  4C7P A;  3L8N A;  4D7Q A;  1R8Q E;  4OIY A;  4A4P A;  1PBV A;  4FQ0 C;  4JMI A;  3TW5 A;  3LTL A;  4KN7 X;  1BC9 A;  4JMO A;  3USY A;  1R8M E;  4C0A A;  2R0D A;  3AJC A;  2K6X A;  3USW A;  1R8S E;  1S9D E;  2HSN A;  1XSZ A;  4KMU X;  3SWV A;  1LKV X;  4JXH A;  1XT0 B;  4JWL A;  4JK1 X;  4D7R A;  4KN4 X;  1KU1 A;  4Z21 A;  4FHR B;  3SOH B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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